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Dahlstrom Jane E JE 1Department of Anatomical Pathology, ACT Pathology, Canberra Hospital 2ANU Medical School, Canberra 3Department of Endocrinology, Canberra Hospital 4Department of Obstetrics and Gynaecology, Calvary Hospital 5John James Medical Centre, Deakin, - - 2014
A 26-year-old Indian lady G2P0 presented at 33 weeks gestation complaining of itch. Liver function tests revealed an elevated alkaline phosphatase (ALKP) of 2983 U/L (normal range 20-110) which on fractionation was a placental or placental-like isoenzyme. All other investigations, including fetal ultrasound, were normal. Labour was induced at 37 weeks ...
Cheung Annie N Y AN Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong - - 2014
Extensive use of ultrasound in early pregnancy has given rise to increased diagnostic dilemma, particularly the differential diagnosis of early complete mole, partial mole and abnormal nonmolar villous lesions. The rare entities of placental mesenchymal dysplasia, twin pregnancy with one complete mole further pose problems. Overdiagnosis of hydatidiform mole in ...
Faye-Petersen Ona Marie OM Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, - - 2014
There is mounting evidence that several placental pathologic entities associated with fetal intrauterine growth restriction and poor and recurrent pregnancy outcomes reflect disruption of mechanisms of immune tolerance normally operative during pregnancy. This presentation update will include an overview studies that have yielded evidence of the role of alloimmune mechanisms, ...
Petukhova N L NL ART Clinic "Test-tube babies" , Moscow , - - 2014
Abstract This study of infertile women prior in vitro fertilization (IVF) is focused at the genetic and acquired thrombophilia before the IVF program, the identification of the frequency of occurrence of thrombophilia in them, the impact of thrombophilia of the offensive, the course and outcome of pregnancies, to improve the ...
Skreden Marianne M 1Department of Public Health,Sports and Nutrition,University of Agder,PO Box 422,4604 - - 2014
To describe changes in consumption of different types of beverages from pre-pregnancy to early pregnancy, and to examine associations with maternal age, educational level and BMI. Cross-sectional design. Participants answered an FFQ at inclusion into a randomized controlled trial, the Fit for Delivery (FFD) trial, in median gestational week 15 ...
Uribe Mari Carmen MC Laboratorio de Biología de la Reproducción, Departamento de Biología Comparada, Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, México, DF, - - 2014
Intraluminal gestation, as it occurs in viviparous goodeids, allows a wide diversity of embryo-maternal metabolic exchanges. The branchial placenta occurs in embryos developing in intraluminal gestation when ovarian folds enter through the operculum, into the branchial chamber. The maternal ovarian folds may extend to the embryonic pharyngeal cavity. A branchial ...
Unterscheider Julia J Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Dublin, - - 2014
Objective This study aims to compare recommendations from recently published national clinical guidelines for pregnancies complicated by fetal growth restriction (FGR). Materials and Methods Clinical guidelines informing best practice management of pregnancies with FGR issued by the American Congress of Obstetricians and Gynecologists, the Society of Obstetricians and Gynaecologists of Canada and ...
Chanprapaph Pharuhas - - 2014
Abstract Background: Multiple first trimester aneuploidy sonomarkers have been introduced recently. Objective: To evaluate the efficacy of first trimester sonomarkers in fetal aneuploidy detection without serum markers. Methods: There were entirely 280 fetuses with 11-13+6 weeks' gestation (crown-rump -length between 45-84 mm) enrolled to assess nuchal translucency thickness (NT), nasal ...
Gore Andrea C AC Division of Pharmacology & Toxicology, University of Texas at Austin, Austin, TX - - 2014
The prenatal brain develops under the influence of an ever-changing hormonal milieu that includes endogenous fetal gonadal and adrenal hormones; placental and maternal hormones; and exogenous substances with hormonal activity that can cross the placental barrier. This review discusses the influences of endogenous fetal and maternal hormones on normal brain ...
Mittal Ankita A Department of Obstetrics and Gynecology, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, 124001, Haryana, India, - - 2014
To evaluate the relationship between sonographic measurements of umbilical cord coiling index during late second trimester of pregnancy and perinatal outcome. This prospective study was conducted on two hundred pregnant women with uncomplicated, singleton pregnancy between 20 to 24 weeks of gestation. The antenatal umbilical coiling index (UCI) was calculated by ...
Brahmalakshmy B L BL Department of Obstetrics-Gynecology, Kasturba Medical College and Hospitals (A Constituent of Manipal University), Mangalore, 575001, - - 2014
There is significant increase in proportion of cases with previous cesarean delivery requiring obstetric care. The available literature fails to provide uniform opinion on each woman's characteristics to identify risk of uterine rupture while planning trial of labor after cesarean. To study the association of abnormal lower uterine segment with ...
Rodriguez A A Hospital de Sabadell, Corporació Sanitària Parc Taulí, Institut Universitari ParcTaulí-UAB, Sabadell, Catalonia, Spain; Universitat Autònoma de Barcelona, Campus d'Excelència Internacional Bellaterra, Catalonia, - - 2014
To investigate the association of maternal circulating 25-hydroxyvitamin D3 [25(OH)D3] concentration with pregnancy and birth outcomes. Prospective cohort study. Four geographical areas of Spain, 2003-2008. Of 2382 mother-child pairs participating in the INfancia y Medio Ambiente (INMA) Project. Maternal circulating 25(OH)D3 concentration was measured in pregnancy (mean [SD] 13.5 [2.2] ...
Taura Junki J Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, - - 2014
The effect of 2,3,4,7,8-pentachlorodibenzofuran (PnCDF) on the fetal pituitary-gonad axis was compared with that produced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Wistar rats. Maternal treatment at gestational day (GD)15 with PnCDF and TCDD reduced the fetal expression at GD20 of pituitary luteinizing hormone (LH) and the testicular proteins necessary for steroidogenesis. The ...
Sanz-Salvador Lucía L L Sanz-Salvador, Obstetrics & Gynecology, Fundación para la Investigación Sanitaria y Biomédica (FISABIO), Valencia, - - 2014
Changes in bone density and in bone markers suggest that pregnancy is associated with deterioration of bone mass in the mother. The metabolism of calcium resets to allow the needs imposed by the building of the fetal skeleton. The fetus contributes in the process through the output of regulators from ...
Wong Luchin F LF University of Utah, Department of Obstetrics and Gynecology, Salt Lake City, UT; Intermountain Healthcare, Department of Maternal-Fetal Medicine, Salt Lake City, UT. Electronic address: - - 2014
To determine obstetric and neonatal outcomes of expectantly managed multi-fetal pregnancies complicated by early preterm premature rupture of membranes (PPROM) prior to 26 weeks. A retrospective cohort of all multi-fetal pregnancies complicated by documented PPROM occurring before 26 0/7 weeks and managed expectantly by a single Maternal-Fetal Medicine practice between ...
Hu Wensheng - - 2014
BackgroundPreeclampsia reduces placental expression and activity of 11ß-hydroxysteroid dehydrogenase type 2 (HSD11B2), leading to an increase in fetal glucocordicoids. The latter has been proposed to be associated with low birth weight and high risk of metabolic diseases in later life of the offspring. This investigation aims to delineate the alteration ...
Mhyre Jill M - - 2014
Case reviews of maternal death have revealed a concerning pattern of delay in recognition of hemorrhage, hypertensive crisis, sepsis, venous thromboembolism, and heart failure. Early-warning systems have been proposed to facilitate timely recognition, diagnosis, and treatment for women developing critical illness. A multidisciplinary working group convened by the National Partnership ...
Stanford Kristin I KI Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, - - 2014
The intrauterine environment during pregnancy is a critical factor in the development of diabetes and obesity in offspring. To determine the effects of maternal exercise during pregnancy on the metabolic health of offspring, 6wk old C57BL/6 virgin female mice were fed a chow (21%) or high-fat (60%) diet and divided ...
van der Wijden Carla L CL Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; Department of Gynaecology, Medisch Centrum Jan van Goyen, Amsterdam, The Netherlands. Electronic address: - - 2014
Gaining too much weight in pregnancy poses health risks for mother and child. Eating style has been shown to be related to weight gain in general but the relation to maternal weight gain in pregnancy is unclear. To assess the influence of emotional, external and restraint eating style on maternal ...
Shiva Marzieh M Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, - - 2014
In recent years, the significant increase in multiple pregnancies as a result of assisted reproductive techniques (ART) has introduced the concept of multifetal reduction techniques. However, it is still unclear whether there are significant advantages of using this technique. To compare the outcomes of triplet pregnancies achieved by ART managed ...
Haig David D Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: - - 2014
The evolution of placentas in poeciliid fishes is associated with conception of overlapping litters and male mating strategies becoming more coercive. Sperm competition in ovaries of multiply-inseminated females may favor fertilization of immature eggs during ongoing pregnancies.
Myers Amanda J AJ Director of Nursing and Operations, British Pregnancy Advisory Service, Stratford upon Avon, - - 2014
UK regulations on managing fetal tissue after pregnancy loss, including abortion, are underscored by the concept of 'sensitive disposal'. This involves offering women burial or cremation and, when disposal is by the health care provider, separating fetal tissue from other clinical waste before incineration. We interviewed 23 women who had ...
Heller Rebecca R Clinical Research Fellow, Chalmers Sexual & Reproductive Health Service, Edinburgh, - - 2014
Requests for termination of pregnancy (TOP) at very early gestation (≤6 weeks) can prove challenging for abortion services as the ultrasound feature usually accepted as definitive evidence of an intrauterine pregnancy (IUP), the presence of a yolk sac within a gestational sac, may not yet be evident. In 2011 the Edinburgh ...
Mantzaris Debbie D Genetic Technologies Ltd, Melbourne, - - 2014
Non-invasive methods to assess the fetal genome during pregnancy will provide new opportunities to offer pregnant women a more comprehensive genetic diagnosis of their established fetus. The aim of this study was to determine the presence and frequency of fetal cells in transcervical cell (TCC) mucus samples from pregnant women ...
Triunfo S S BCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Deu), University of Barcelona, Sabino de Arana, 1, 08028, Barcelona, Spain, - - 2014
Maternal malnutrition, ranging from under nutrition to over dietary intake before and in the pregnant state, is worldwide problem with significant consequences, not only for survival and increased risk for acute and chronic diseases both in mother and child, but also for economic productivity of individuals in the societies and ...
Qiao Chong C Department of Obstetrics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, China - - 2014
A human isoform of Collapsin Response Mediator Protein (CRMP) family proteins, CRMP-1, has been identified as a novel invasion suppressor. The aim of this study was to determine CRMP-1 expression pattern in placentas during normal pregnancy and elucidate the clinical significance of CRMP-1 expression in the placentas of women with ...
Papageorghiou Aris T AT Nuffield Department of Obstetrics and Gynaecology, and Oxford Maternal and Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, - - 2014
In 2006, WHO produced international growth standards for infants and children up to age 5 years on the basis of recommendations from a WHO expert committee. Using the same methods and conceptual approach, the Fetal Growth Longitudinal Study (FGLS), part of the INTERGROWTH-21(st) Project, aimed to develop international growth and ...
Morales E E 1] Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Catalonia, Spain [2] Hospital del Mar Medical Research Institute (IMIM), Barcelona, Catalonia, Spain [3] Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain [4] CIBER Epidemiología y Salud Pública (CIBERESP), - - 2014
Background:Maternal vitamin D status during fetal development may influence offspring growth and risk of obesity; however, evidence in humans is limited.Objective:To investigate whether maternal circulating 25-hydroxyvitamin D3 [25(OH)D3] concentration in pregnancy is associated with offspring prenatal and postnatal growth and overweight.Methods:Plasma 25(OH)D3 concentration was measured in pregnant women (median weeks ...
Romero Roberto R Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD and Detroit, MI, - - 2014
Abstract Objective: The objectives of this study were to: 1) determine the amniotic fluid (AF) microbiology of patients with preterm prelabor rupture of membranes (PROM); and 2) examine the relationship between intra-amniotic inflammation with and without microorganisms (sterile inflammation) and adverse pregnancy outcomes in patients with preterm PROM. Methods: AF ...
Gentile Salvatore S Mental Health Center n. 63 Cava de'Tirreni, ASL Salerno, Department of Mental Health , Piazza Galdi, 841013 Cava de' Tirreni, Salerno , Italy +39 089 4455439 ; +39 089 4455440 ; - - 2014
Introduction: Assessment of the metabolic safety of second-generation antipsychotics (SGAs) is mandatory in pregnant women, where the occurrence of metabolic complications and, especially, gestational diabetes mellitus (GDM) may severely impact on pregnancy and fetal outcomes. Areas covered: The aim of this article is to review published data reporting the occurrence ...
Sepulveda W W Fetalmed-Maternal-Fetal Diagnostic Center, Las Condes, Santiago, - - 2014
To describe the sonographic features of fetal cephalocele diagnosed at the time of the first-trimester ultrasound screening for aneuploidy. Retrospective review of cases diagnosed at four Fetal Medicine referral centers. A total of 35 affected fetuses were identified; 33 were from a singleton pregnancy and two from twin pregnancies in ...
Canavan Timothy P TP Magee Women's Hospital-University of Pittsburgh, Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Ultrasound, 300 Halket Street, Pittsburgh, PA, - - 2014
To compare the estimated fetal weight (EFW), abdominal circumference (AC), and femur length (FL), measured on sonographic (US) examinations at 28-34 weeks of gestation to determine the best predictor of macrosomia at birth. We retrospectively evaluated 3,857 consecutive, term, singleton pregnancies. The AC, FL, and EFW were compared with birth ...
Gaskins Audrey J AJ Departments of Nutrition and Epidemiology, Harvard School of Public Health, the Department of Obstetrics, Gynecology and Reproductive Biology, and the Channing Division of Network Medicine and the Connors Center for Women's Health and Gender Biology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Vincent Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, and the Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, - - 2014
To examine prospectively the relationships of prepregnancy body mass index (BMI), BMI at age 18 years, and weight change since age 18 years with risk of fetal loss. Our prospective cohort study included 25,719 pregnancies reported by 17,027 women in the Nurses' Health Study II between 1990 and 2009. In ...
Wenstrom Katharine D KD Women & Infants Hospital of Rhode Island, Warren G. Alpert Medical School of Brown University, Providence, Rhode - - 2014
Since the first human fetal surgery was reported in 1965, several different fetal surgical procedures have been developed and perfected, resulting in significantly improved outcomes for many fetuses. The currently accepted list of fetal conditions for which antenatal surgery is considered include lower urinary tract obstruction, twin-twin transfusion syndrome, myelomeningocele, ...
Mhyre Jill M JM Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas; the Central Jersey Family Health Consortium, Inc., North Brunswick, New Jersey; the Departments of Cardiology and Maternal-Fetal Medicine, University of California, Irvine, Irvine, California; the Department of Reproductive Biology, Case Western Reserve University School of Medicine and the Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, Ohio; the School of Nursing, Vanderbilt University, Nashville, Tennessee; the Department of Obstetrics and Gynecology, Maternal-Fetal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa; the Department of Obstetrics and Gynecology, Rush University Medical Center, Chicago, Illinois; the Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Women's Health, University of Louisville, Louisville, Kentucky; and the Department of Obstetrics & Gynecology, Maternal-Fetal Medicine, Columbia University Medical Center, New York, New - - 2014
Case reviews of maternal death have revealed a concerning pattern of delay in recognition of hemorrhage, hypertensive crisis, sepsis, venous thromboembolism, and heart failure. Early-warning systems have been proposed to facilitate timely recognition, diagnosis, and treatment for women developing critical illness. A multidisciplinary working group convened by the National Partnership ...
Taebi Mahboubeh M Department of Midwifery, Isfahan University of Medical Sciences, Isfahan, - - 2014
Preeclampsia is a major cause of maternal death and morbidity. Body mass index (BMI) predicts an increased risk of developing hypertensive disorders and preeclampsia. However, waist-to-hip ratio (WHR), as a central obesity index, has not been assessed in predicting this disorder in pregnancy. We assumed that WHR might be more ...
Alkandari Farah F Department of Child Health, University of Aberdeen, Aberdeen, - - 2014
Several hypotheses predict that faltering fetal growth is an antecedent for common non-communicable diseases. This is the first systematic review of an emerging literature linking antenatal fetal measurements to postnatal outcomes. Electronic databases (OVID, EMBASE and Google Scholar) and cohort study websites were searched in July 2014. Studies were selected ...
Hughes Ruth C E RC Department of Obstetrics and Gynecology, University of Otago, Christchurch Women's Hospital, Christchurch, New Zealand - - 2014
Pregnant women with undiagnosed diabetes are a high-risk group that may benefit from early intervention. Extrapolating from nonpregnancy data, HbA1c ≥6.5% (48 mmol/mol) is recommended to define diabetes in pregnancy. Our aims were to determine the optimal HbA1c threshold for detecting diabetes in early pregnancy as defined by an early ...
Zhang Chong C Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, - - 2014
The hypothalamic-pituitary-adrenal (HPA) axis is one of the most important neuroendocrine axes and plays an important role in stress defense responses before and after birth. Prenatal exposure to xenobiotics, including environmental toxins (such as smoke, sulfur dioxide and carbon monoxide), drugs (such as synthetic glucocorticoids), and foods and beverage categories ...
Barisic Ingeborg I Children's Hospital Zagreb, University of Zagreb School of Medicine, Zagreb, - - 2014
Meckel-Gruber Syndrome is a rare autosomal recessive lethal ciliopathy characterized by the triad of cystic renal dysplasia, occipital encephalocele and postaxial polydactyly. We present the largest population-based epidemiological study to date using data provided by the European Surveillance of Congenital Anomalies (EUROCAT) network. The study population consisted of 191 cases ...
Al-Amin Ahmed A Department of Perinatal Medicine, Royal Women's Hospital, Melbourne, Victoria, - - 2014
Abstract Objective: To determine the utility of ultrasound in late pregnancy for identifying foetuses with growth disturbances. Methods: This study was designed as a retrospective study of birth weights over a 12 months period at the Royal Hobart Hospital (RHH) and Barwon Health (BH). Data was collected from the discharge ...
Cordina Mark M Maternal Hypertension Unit, King's College - - 2014
Abstract Objective. To examine the relationship between maternal haemoglobin concentration (Hb) at 27-29 weeks' gestation and severity of pre-eclampsia (PE). Methods. This was a retrospective study of maternal Hb at 27-29 week in 497 pregnancies that developed PE and 497 healthy controls with normal pregnancy outcomes. Multiple regression analysis was ...
Zhu JiaYu J Department of Obstetrics and Gynecology, Nanfang Hospital of Southern Medical University, Guangzhou 510515, - - 2014
Trophoblast invasion into the maternal endometrium serves an important function in human pregnancy. Dysregulation of the finely controlled process of trophoblast invasion can result in a wide spectrum of pregnancy abnormalities. We aimed to elucidate the relationship between the expression of matrix metalloproteinases and pregnancy complication. The study group consisted ...
Wender-Ozegowska Ewa E Department of Obstetrics and Women's Diseases, University of Medical Sciences , Poznan , - - 2014
Objectives: To investigate into an association between circulating levels of vascular factors (VF: ACE, eNOS, PlGF and VEGF) and impaired fetal growth measured as a small for gestational age newborn (SGA) in women with gestational hypertension/preeclampsia. Methods: A prospective observational trial in 46 patients in singleton pregnancies. Concentrations of VF ...
Vaiman Daniel D Cochin Institute, U1016 INSERM, UMR8104 CNRS, Paris Descartes University. 24 rue du faubourg St Jacques, 75014 Paris, - - 2014
Recurrent pregnancy loss, defined as a pregnancy failure occurring before 24 weeks of gestation more than two or three times according to most definitions, is a fertility defect encountered in 1-5% of the patients. This defect is of course of multifactorial origin. Among the possible origins of recurrent pregnancy loss ...
Huilaja Laura - - 2014
Gestational pemphigoid (pemphigoid gestationis, PG) is a rare autoimmune skin disorder occurring characteristically during pregnancy. Autoantibodies against placental BP180 (also known as BPAG2 or collagen XVII) cause damage to the skin basement membrane, resulting in severe itching and blistering rash over the body and the extremities. The diagnosis of PG ...
Gupta Simi S From Maternal-Fetal Medicine Associates, PLLC, New York, New York USA (S.G.); and Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, New York University School of Medicine, New York, New York USA (S.G., I.E.T.-T., C.O., J.C., A.M.). - - 2014
Fetal anatomic surveys are difficult to perform on obese patients. However, there are limited data available on methods to improve the rate of complete anatomy scans in these patients. The objective of this study was to determine whether the addition of an early second-trimester fetal anatomy scan improves the rate ...
Hu Maowen M Department of Radiology, University of California, San Francisco, California - - 2014
New early first-trimester diagnostic criteria for nonviable pregnancy recommended by the Society of Radiologists in Ultrasound via a multispecialty consensus panel extended the diagnostic size criteria of crown-rump length from 5 to 7 mm for embryos without a heartbeat and mean sac diameter from 16 to 25 mm for "empty" ...
Liu Dennis B DB Ann and Robert H. Lurie Children's Hospital of Chicago, Department of Urology, Northwestern University Feinberg School of Medicine, 225 East Chicago Avenue, Box 24, Chicago, IL 60611, USA. Electronic address: - - 2014
Antenatal hydronephrosis (ANH) is one of the most frequently detected abnormalities found on routine prenatal ultrasounds, affecting 1% to 4.5% of all pregnancies. Despite its prevalence, there continues to be uncertainty regarding the clinical impact after birth. Prognosis depends on the severity of the dilation. Expectant prenatal management is the ...
OuYang Zhenbo Z Department of Gynecology, Guangdong No. 2 Provincial People's Hospital, Guangzhou, China (Z.O., Y.M., Q.Z.); Department of Obstetrics and Gynecology, Nanfang Hospital of Southern Medical University, Guangzhou, China (Q.Y., Y.Y.); and Department of Obstetrics and Gynecology, Weifang People's Hospital, Weifang, China (Y.X.). - - 2014
Heterotopic cesarean scar pregnancy is a rare, life-threatening form of ectopic pregnancy. To provide information regarding the clinical manifestations, diagnosis, management, and prognosis of this condition, we reviewed all cases reported in the English literature. All literature on heterotopic cesarean scar pregnancy was retrieved by searching the PubMed database and ...
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