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Glover Vivette V Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, W12 0NN, London, UK, - - 2015
Many prospective studies have shown that if a mother is depressed, anxious or stressed while pregnant, this increases the risk for her child having a wide range of adverse outcomes including emotional problems, symptoms of attention deficit hyperactivity disorder (ADHD) or impaired cognitive development. Although genetics and postnatal care clearly ...
King Suzanne S Department of Psychiatry, McGill University, Montreal, QC, Canada, - - 2015
Animal studies of prenatal maternal stress permit random assignment of pregnant animals to stress and no-stress groups, and allow total control of the type, severity, and timing of the stressor in utero. Human studies have obvious constraints that make the use of experimental methods nearly impossible. Studying pregnant women who ...
Gatzke Noah N Noah Gatzke is an emergency Nurse Practitioner at Health Sciences Centre, Adult ER, Winnipeg, MB. Laura Johnson is an instructor at the University of Manitoba, Faculty of Nursing, and a Nurse Practitioner Health Sciences Center Adult Emergency, Winnipeg, - - 2014
: Ectopic pregnancy (EP) is a leading cause of maternal morbidity and mortality. Rates of EP have declined, yet ethnic, socioeconomic, and age-related disparities persist. Improved ultrasound resolution, the use of emergency transvaginal ultrasounds, and improved lab sensitivity have enabled earlier diagnosis, which could further improve outcomes for patients with ...
Green Sarah B SB Sarah B. Green, Pharm.D., is Postgraduate Year 1 Pharmacy Practice Resident, WakeMed Health and Hospitals, Raleigh, NC; at the time of writing she was Intern, Drug Information, Department of Pharmacy, University of North Carolina Hospitals (UNCH), Chapel Hill. Ashley L. Pappas, Pharm.D., BCPS, is Pharmacy Specialist, Drug Information, Department of Pharmacy, UNCH. - - 2014
A review of case reports and other published data on fetal and neonatal outcomes associated with maternal use of bisphosphonate medications is presented. Bisphosphonates can persist in the bone matrix for years, even after therapy is discontinued, potentially resulting in fetal bisphosphonate exposure during pregnancy. Adverse effects of bisphosphonates on ...
Baska-Vincze Boglárka B Szent István University Equine Department and Clinic, Faculty of Veterinary Science Dóra major H-2225 Üllő - - 2014
In the equine practice, attempts have been made to examine the fetus in the second and third trimester of pregnancy but all of the available methods have limitations. Until now, transabdominal ultrasonography has been regarded as the most informative examination. This method allows us to measure fetal heart rate, fetal ...
Matsui Doreen D Department of Paediatrics and Medicine, Children's Hospital, London Health Sciences Centre, Child Health Research Institute, University of Western Ontario, 800 Commissioners Road East, London, ON, N6A 5W9, Canada, - - 2014
Pregnant women with illness require efficacious and safe drug therapy during pregnancy; however, their treatment is often hindered by a lack of information regarding the use of medications during pregnancy. Ethical challenges are encountered in conducting drug trials in pregnant women, who are often excluded from participation due to fear ...
Kamei Koichi K Department of Nephrology and Rheumatology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, - - 2014
Fetal anemia is caused by Rhesus (RhD) sensitization as a result of RhD incompatibility during pregnancy. The severe form of this disease can cause hydrops fetalis leading to intrauterine death. We experienced a highly sensitized 39-year-old woman with B Rh-negative blood. She had a history of three induced abortions and ...
Maso G G Department of Obstetrics and Gynaecology, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste (Italy) - - - 2014
Electronic fetal monitoring (EFM) has been introduced in the obstetrics practice as a test to identify the first signs of fetal deterioration, allowing a prompt intervention to reduce neonatal morbidity and mortality. However, results from clinical trials fail to demonstrate a clear benefit with the use of EFM. No decrease ...
Dubova E A EA V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, the Ministry of Health of the Russian Federation, Moscow, Russia, - - 2014
Placental levels of caspase 1, 8, and 10 were studied by the immunohistochemical method in full-term spontaneous and induced pregnancies. The levels of these caspases in the placental terminal villi were significantly higher in induced pregnancy. The changes were more marked after intracytoplasmatic injection of spermatozoa.
Artunc Ulkumen B B Division of Perinatology, Department of Obstetrics and Gynecology, Celal Bayar University School of Medicine , Manisa , - - 2014
We aimed to evaluate the volumetric and echogenic alterations in placentas between the intrauterine growth restriction (IUGR) and normal pregnancies using three-dimensional ultrasound and virtual organ computer-aided analysis (VOCAL) software. This case-control prospective study consisted of 48 singleton pregnancies complicated by IUGR and 60 healthy singleton pregnancies matched for maternal ...
Tantrakul Visasiri - - 2014
Evaluation of Berlin and Stop-Bang questionnaires in detecting obstructive sleep apnea (OSA) across trimesters of pregnancy. Pregnant women from a high-risk pregnancy clinic were recruited to complete sleep evaluations including Berlin and Stop-Bang Questionnaires. Overnight testing with Watch-PAT200 for diagnosis of OSA (cutoff point of apnea-hypopnea index ≥5 events/h) was ...
El-Dakdoky Mai Helmy MH Zoology Department, Women College for Arts, Science and Education, Ain Shams University, 1 Asmaa Fahmey St., Heliopolis, Cairo 11757, - - 2014
Abstract Mefloquine (MQ) is a potent effective antimalarial drug against multiple drug-resistant Plasmodium falciparum. All agree that MQ can be given safely during the second and third trimesters. However, there is very limited information on the drug safety during the first trimester. The aim of the present work was to ...
Patel Jignesh P - - 2014
BackgroundIt is well accepted that the gravid state is hypercoagulable and a significant cause of both maternal morbidity and mortality in the Western world. Although thrombin generation is reported to be increased in pregnant women, uncertainty exists on the pattern of thrombin generation change during this time. The aim of ...
Walsh Judi - - 2014
BackgroundMaternal-fetal relationships have been associated with psychosocial outcomes for women and children, but there has been a lack of conceptual clarity about the nature of the maternal relationship with the unborn child, and inconsistent findings assessing its predictors. We proposed and tested a model whereby maternal-fetal relationship quality was predicted ...
Frasch Martin G MG Department of Obstetrics and Gynecology and Department of Neuroscience, CHU Sainte-Justine Research Centre, University of Montreal, Montreal, Quebec, - - 2014
Fetal monitoring during labour currently fails to accurately detect acidemia. We developed a method to assess the multidimensional properties of fetal heart rate variability (fHRV) from trans-abdominal fetal electrocardiogram (fECG) during labour. We aimed to assess this novel bioinformatics approach for correlation between fHRV and neonatal pH or base excess ...
Cutts Diana B DB Department of Pediatrics, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN, 55415, USA, - - 2014
Evaluate homelessness during pregnancy as a unique, time-dependent risk factor for adverse birth outcomes. 9,995 mothers of children <48 months old surveyed at emergency departments and primary care clinics in five US cities. Mothers were classified as either homeless during pregnancy with the index child, homeless only after the index child's ...
Thrift Aaron P AP Population Health, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. - - 2014
To assess whether the effect of pre-pregnancy overweight or obesity on maternal complications and perinatal outcomes is modified by Indigenous status. Population-based study using de-identified aggregate data on pregnancies resulting in singleton births from Indigenous (n = 13 582) and non-Indigenous (n = 241 270) women from the Queensland Perinatal Data Collection, 1 July 2007 to ...
Vigeh Mohsen M a Department of Hazard Assessment , National Institute of Occupational Safety and Health , Kawasaki , - - 2014
To clarify the relationship of prenatal arsenic exposure to hemoglobin concentrations and anemia during pregnancy, a longitudinal study was conducted of 364 participants during early pregnancy from October 2006 to March 2011 in Tehran, Iran. Maternal whole blood (taken between 8-12 and 20-24 weeks of gestation, and at delivery) and umbilical ...
Khan Raheela N RN Division of Medical Sciences & Graduate Entry Medicine, School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Uttoxeter Road, Derby DE22 3DT, UK - - 2014
When the normal progression of pregnancy is threatened, inflammatory processes are often amplified in order to minimize detrimental effects and eliminate noxious agents. Inflammasomes are unique, intracellular, multiprotein assemblies that enable caspase-1 mediated proteolytic processing of the proinflammatory cytokine interleukin-1β, levels of which are elevated in some forms of preterm ...
Wu Xin X Hunan Engineering and Research Center of Animal and Poultry Science, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, 410125, Changsha, China, - - 2014
The present review focuses on the physiological functions of glutamate-glutamine exchange involving placental amino acid transport and umbilical amino acid uptake in mammals (particularly in sows), with special emphasis on the associated regulating mechanisms. Glutamate plus glutamine are among the most abundant and the most utilized amino acids in fetus ...
Egloff Matthieu M Service d'Histologie-Embryologie-Cytogénétique, Hôpital Necker-Enfants Malades, Paris, - - 2014
Ultrasound examination performed on a 36-year-old woman at 33 weeks of gestation showed the presence of isolated and bilateral ventriculomegaly in the fetus. Array-based comparative genomic hybridization (array-CGH) performed on uncultured amniocytes at 35 weeks of gestation revealed a 17q21.31 microdeletion. After genetic counseling, the pregnancy was terminated at 37 ...
Duffett Lisa L Thrombosis Program, Division of Hematology, Department of Medicine, University of Ottawa, Ottawa, ON, - - 2014
Placenta-mediated pregnancy complications, including preeclampsia, placental abruption, intrauterine growth restriction/small for gestational age and recurrent or late pregnancy loss, affect over 5% of pregnancies and can result in significant maternal and perinatal morbidity and mortality. These complications have been suggested to at least partly arise from placental insufficiency, possibly as ...
Prefumo Federico F Maternal-Fetal Medicine Unit, Department of Obstetrics and Gynaecology, University of Brescia, - - 2014
To describe the natural history of monoamniotic twin pregnancies in contemporary practice. Cohort study of monochorionic monoamniotic twin pregnancies with two live fetuses diagnosed at less than 16 weeks and prospectively followed up between 2004 and 2013. A systematic review of the literature using Medline, Embase and Scopus, to determine the ...
Mitchell Lisa M LM Department of Anthropology, University of Victoria. - - 2014
Some North American hospitals now offer parents the opportunity to see, hold, and photograph fetal remains after pregnancy loss. I explore the social, material, and interpretive strategies mobilized to create this fetal visibility after second trimester-induced abortion for fetal anomaly. My analysis examines both the discursive framing of fetal remains ...
Garg Amit X AX The authors' affiliations are provided in the - - 2014
Background Young women wishing to become living kidney donors frequently ask whether nephrectomy will affect their future pregnancies. Methods We conducted a retrospective cohort study of living kidney donors involving 85 women (131 pregnancies after cohort entry) who were matched in a 1:6 ratio with 510 healthy nondonors from the ...
Nunes Carla C CHLN - Hospital Universitário de Santa Maria, Departamento / Clínica Universitária de Obstetrícia e Ginecologia, Avenida Professor Egas Moniz, 1649-035 Lisboa, Portugal, Lisboa, - - 2014
Abstract Introduction: Fetal body tumors are rare, but the ability to diagnose them has improved over recent years. Most masses discovered in the chest results from fetal bronchopulmonary malformations, such as congenital cystic adenomatoid malformation and bronchopulmonary sequestration. Congenital cystic adenomatoid malformation and bronchopulmonary sequestration have a reported incidence of ...
Kesmodel Us U Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, - - 2014
To examine the effects of pre-pregnancy alcohol drinking on child neuropsychological functioning. Prospective follow-up study. 154 women and their children sampled from the Danish National Birth Cohort. Participants were sampled based on maternal alcohol consumption before pregnancy. At 5 years of age, the children were tested with the Wechsler Preschool and ...
Kieler H H Department of Medicine Solna, Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, - - 2014
To assess whether the use of selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, mirtazapine, venlafaxine or other antidepressants is associated with late elective termination of pregnancy. Case-control study using data from national registers. Denmark, Finland, and Norway during the period 1996-2007. A total of 14 902 women were included as cases ...
Bhorat I E IE Department of Obstetrics and Gynaecology, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Durban, Kwa-Zulu Natal, South - - 2014
To determine the fetal modified myocardial performance index (Mod-MPI) and E-wave/A-wave peak velocities (E/A ratio) in deteriorating grades of intrauterine growth restriction (IUGR) and its link to adverse outcomes defined as perinatal death, hypoxic ischaemic encephalopathy, neonatal resuscitation, neonatal cord pH <7.15, intraventricular haemorrhage and bronchopulmonary dysplasia. Forty three pregnant ...
Richardson A A Nurture Fertility, The East Midlands Fertility Clinic, Nottingham, NG10 5QG, UK; Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham, NG7 2UH, - - 2014
To evaluate the diagnostic accuracy of ultrasound in confirming intrauterine pregnancy location prior to development of the yolk sac. The systematic review was conducted in accordance with PRISMA and registered with PROSPERO. We searched MEDLINE, Embase and the Cochrane Library for citations. Studies were selected in a two-stage process and ...
Brown Nicole N Mater Centre for Maternal Fetal Medicine, Mater Mothers' Hospital, South Brisbane, Queensland, 4101, - - 2014
The aim of this study was to investigate the prenatal ultrasound features that were associated with intrapartum fetal distress in fetuses with gastroschisis. This was a retrospective observational study of all cases of gastroschisis referred to and delivering at the Mater Mothers' Hospital in Brisbane, Australia. Maternal demographics, prenatal ultrasound ...
Kaya Barış B Department of Obstetrics and Gynaecology, Near East University, North Cyprus, - - 2014
Preeclampsia is a pregnancy-specific disease with the increased risk of maternal morbidity and mortality. It is characterised by placental vascular dysfunction. Despite the numerous studies on preeclampsia, studies evaluating proliferation of villous trophoblasts in preeclamptic placentas are limited. Ki67 is a proliferation marker that expresses in the nuclei of proliferating ...
Rabie Nader N University of Arkansas for Medical Sciences, Obstetrics and Gynecology, 4301 W. Markham St. #518, Little Rock, 72205 United - - 2014
Abstract Objective Describe a novel system of coordinating the identification and management of fetal anomalies in a rural state, where there is a large proportion of impoverished and Medicaid eligible patients, and centralization of the majority of tertiary care resources. Methods The Arkansas Fetal Diagnosis and Management program was initiated ...
Fahey Jenifer O - - 2014
The ongoing and well-documented debate about the value of electronic fetal monitoring has focused primarily on the fact that most variant fetal heart rate (FHR) patterns are poor predictors of fetal acid-base status. Most recently, much of this attention has been focused on the implications for clinical management of FHR ...
Mei-Dan Elad - - 2014
Abstract Objective: To evaluate a possible dose-response relationship between active maternal smoking during pregnancy and adverse perinatal outcome. Design: Retrospective cohort study. Setting: Population-based in Montreal, Quebec, Canada. Population: Women who gave birth to a liveborn or stillborn infant during the period of January 2001 to December 2007. Methods: Active ...
Johansen Rie Laurine Rosenthal RL Section of Social Medicine, Department of Public Health, University of Copenhagen, Copenhagen, - - 2014
The use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy has been associated with miscarriage, but the association may be biased by maternal mental illness, lifestyle and exposure misclassification. A register study on all pregnancies in Denmark between 1996 and 2009 was conducted using individualised data from the Danish National ...
Madazli R R Department of Obstetrics and Gynecology, Cerrahpaşa Medical Faculty, Istanbul University , Istanbul , - - 2014
The aim of this study was to describe maternal and fetal characteristics associated with intrahepatic cholestasis of pregnancy (ICP) and to determine clinical and biochemical predictors of fetal complications. A total of 89 singleton pregnancies with ICP were analysed, retrospectively. All data concerning laboratory results, symptom onset time, treatment response, ...
Vesterinen Hanna M HM UCSF Program on Reproductive Health and the - - 2014
Abstract Objective: Glomerular filtration rate (GFR) may influence concentrations of biomarkers of exposure and their etiologic significance in observational studies of associations between environmental contaminants and fetal growth. It is unknown whether the size of a developing fetus affects maternal GFR such that a small fetus leads to reduced plasma ...
Vandenbroucke Tineke T KU Leuven - University of Leuven, Department of Oncology , Herestraat 49, B-3000 Leuven , Belgium +32 16 34 42 52 ; +32 16 34 42 05 ; - - 2014
Introduction: The treatment of cancer during pregnancy is challenging because of the involvement of two individuals and the necessity of a multidisciplinary approach. An important concern is the potential impact of chemotherapy on the developing fetus. Areas covered: The authors review the available literature on neonatal and long-term outcome of ...
Unger Holger W HW Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia; Walter and Eliza Hall Institute (WEHI), Parkville, Australia; Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea; Department of Obstetrics and Gynaecology, University of Papua New Guinea, Port Moresby, Papua New Guinea; Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; Barcelona Centre for International Health Research (CRESIB), Barcelona, - - 2014
We conducted a prospective longitudinal study of fetal size in rural Papua New Guinea (PNG) involving 439 ultrasound-dated singleton pregnancies with no obvious risk factors for growth restriction. Sonographically estimated fetal weights (EFWs; N = 788) and birth weights (N = 376) were included in a second-order polynomial regression model ...
Børdahl Per E PE Department of Obstetrics and Gynecology, Haukeland University Hospitals/University of Bergen, Bergen, - - 2014
Christian Kielland (1871-1941) designed his forceps to facilitate delivery from the mid-pelvis in cases of malrotation: occipito-transverse and occipito-posterior positions of the fetal head. It was also used for high transverse arrest, today a certain indication for cesarean section. From the very beginning there were professional objections to the use ...
Catalano R A RA School of Public Health, University of California Berkeley, Berkeley, California, - - 2014
Human conception cohorts in gestation during stressful times reportedly yield lower ratios of male to female live births than do other conception cohorts. Much literature attributes this phenomenon to spontaneous abortion of less fit male fetuses. Controversy remains, however, as to whether stressful times make males fetuses less fit ("Shifting ...
Jensen Morten Søndergaard MS From the aDepartment of Pediatrics, Regional Hospital of Randers; bPerinatal Epidemiology Research Unit, Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark; cSchool of Bioscience, University of Nottingham, United Kingdom; dDanish Center for Neonatal Screening, Department of Clinical Biochemistry and Immunology, Statens Serum Institute, Copenhagen, Denmark; eDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden; fDepartment of Occupational and Environmental Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark; gReproductive Endocrinology, Leibniz Institute for Farm Animal Biology, Dummerstorf, Germany; and hDanish Ramazzini Center, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, - - 2014
Prenatal exposure to phthalates may pose a threat to human male reproduction. However, additional knowledge about the in vivo effect in humans is needed, and reported associations with genital abnormalities are inconclusive. We aimed to study prenatal di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) exposure in relation to cryptorchidism, hypospadias, ...
Savas Nurten N Nurten Savas, Department of Gastroenterology, Baskent Universitesi Hastanesi, 06990 Istanbul, - - 2014
Gastrointestinal endoscopy has a major diagnostic and therapeutic role in most gastrointestinal disorders; however, limited information is available about clinical efficacy and safety in pregnant patients. The major risks of endoscopy during pregnancy include potential harm to the fetus because of hypoxia, premature labor, trauma and teratogenesis. In some cases, ...
Avent Neil D ND Plymouth University Peninsula Schools of Medicine and Dentistry, Portland Square Building, Drake Circus, Plymouth, PL4 8AA, - - 2014
Incompatibility of red cell and platelet antigens can lead to maternal alloimmunization causing hemolytic disease of the fetus & newborn and fetal neonatal alloimmune thrombocytopenia respectively. As the molecular background of these polymorphisms emerged, prenatal testing using initially fetal DNA obtained from invasively obtained amniotic fluid or chorionic villus was ...
van Klink Jeanine M M JM Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The - - 2014
To evaluate the incidence, type and severity of cerebral injury in the surviving monochorionic co-twin after single fetal demise. We included all monochorionic pregnancies with single fetal demise evaluated at our center between 2002 and 2013. We recorded perinatal characteristics, neonatal outcome and presence of cerebral injury on neuroimaging in ...
Payne Janet M - - 2014
BackgroundMidwives are an influential profession and a key group in informing women about alcohol consumption in pregnancy and its consequences. There are no current quantitative Australian data on midwives¿ knowledge, attitudes and practice in relation to alcohol consumption during pregnancy and Fetal Alcohol Spectrum Disorder. We aimed to reduce this ...
Lo Jamie O JO Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, - - 2014
Abstract Objective: We examined the morbidities from delivery at earlier gestational ages versus intrauterine fetal demise (IUFD) for women with intrahepatic cholestasis of pregnancy (ICP) to determine the optimal gestational age for delivery. Methods: A decision-analytic model was created to compare delivery at 35 through 38 weeks gestation for different ...
Furnica R M RM Department of Endocrinology, Université catholique de Louvain, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, - - 2014
Isolated hypothyroxinemia (IH) is defined as a thyroxine level in the lower 5th (severe IH) or 10th percentile (mild IH) of the pregnancy-related reference range and a normal TSH. The etiology of IH remains unknown. This review aims to evaluate the biochemical criteria used to define IH in different published ...
Vrecenak Jesse D JD Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia Pa., - - 2014
Background: The outcomes of prenatally diagnosed lung lesions in the context of multigestational pregnancies are unknown. Methods: Of 960 fetal lung lesion cases evaluated at a single tertiary center over 16 years, 30 occurred in multigestational pregnancies. We reviewed this series to aid in prenatal counseling of affected families and ...
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