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Results 301 - 350 of 975
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Lalevée S S Laboratory for Prenatal Medicine, Department of Biomedicine, University Hospital Basel, Basel CH-4031, - - 2014
Preeclampsia is a severe pregnancy-related disorder and a leading cause of maternal and fetal mortality worldwide. Early identification of patients with an increased risk for preeclampsia is thus one of the most important goals in obstetrics. Here we identify two related human microRNAs as potential biomarkers to detect at-risk pregnancies. ...
Holland Danielle D 0000-0003-4407-6771 Eastern Virginia Medical School, 604 Fairfax Avenue Norfolk, VA 23507, - - 2014
Although incomplete spontaneous abortions are common in early pregnancy, fetal decapitation does not specifically appear in the medical literature as a known complication of spontaneous abortion. We present a rare and unusual case of an incomplete spontaneous abortion occurring at home with the mother presenting to the emergency department (ED) ...
Sachan Rekha R Department of Obstetrics and Gynaecology, King George's Medical University, Lucknow, Uttar Pradesh, - - 2014
Uterine torsion is defined as a rotation of the uterus of more than 45° along its long axis. It is a rare complication during pregnancy; a common cause of torsion can be uterine myoma. Here we describe the case of a 27-year-old G2P1+0 woman at 15 weeks 3 day pregnancy, who presented ...
Chitty Lyn S LS UCL Institute of Child Health, Great Ormond Street Hospital for Children NHS Foundation Trust and University College London Hospitals NHS Foundation Trust, London WC1N 3BH, UK - - 2014
To assess the accuracy of fetal RHD genotyping using cell-free fetal DNA in maternal plasma at different gestational ages. A prospective multicentre cohort study. Seven maternity units in England. RhD negative pregnant women who booked for antenatal care before 24 weeks' gestation. Women who gave consent for fetal RHD genotyping ...
Kacerovsky Marian M Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine in Hradec Kralove, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic; Biomedical Research Center, University Hospital in Hradec Kralove, Hradec Kralove, Czech - - 2014
To determine the association between the presence of oligohydramnios, determined as an amniotic fluid index ≤ 5 cm and the intra-amniotic inflammatory response, fetal inflammatory response and neonatal outcomes in actively managed preterm prelabor rupture of membranes (PPROM). Women with singleton pregnancies complicated by PPROM at a gestational age of ...
Schlütter Jacob Mørup JM Department of Obstetrics and Gynecology, Aarhus University Hospital, Skejby, Aarhus, - - 2014
To identify factors influencing the number of fetal cells in maternal blood. A total of 57 pregnant women at a gestational age of weeks 11-14 were included. The number of fetal cells in maternal blood was assessed in 30 ml of blood using specific markers for both enrichment and subsequent ...
Li Hui H Department of Pathology, West China Second University Hospital, Sichuan University Chengdu, - - 2014
In this paper, we described a placenta with vesicular lesions in a 23-year-old woman (1-gravid) who visited our hospital at 13 weeks of gestation on prenatal routine examination. Ultrasound findings showed multiple vesicular lesions which gradually increased as the pregnancy advanced, and a live normal-appearing fetus which was confirmed of ...
Than Nándor Gábor NG Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S. Department of Health and Human Services , Bethesda, MD, and Detroit, MI , USA ; Department of Obstetrics and Gynecology, Wayne State University School of Medicine , Detroit, MI , USA ; Maternity Private Department, Kútvölgyi Clinical Block, Semmelweis University , Budapest , Hungary ; Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences , Budapest , - - 2014
Galectins are glycan-binding proteins that regulate innate and adaptive immune responses, and some confer maternal-fetal immune tolerance in eutherian mammals. A chromosome 19 cluster of galectins has emerged in anthropoid primates, species with deep placentation and long gestation. Three of the five human cluster galectins are solely expressed in the ...
Marseglia Lucia L Neonatal and Pediatric Intensive Care Unit, Department of Pediatrics, University of Messina, Via Consolare Valeria 1, 98125 Messina, - - 2014
Oxidative stress is worldwide recognized as a fundamental component of the aging, a process that begins before birth. There is a critical balance between free radical generation and antioxidant defenses. Oxidative stress is caused by an imbalance between the production of free radicals and the ability of antioxidant system to ...
Anyfantakis Dimitrios D Primary Health Care Centre of Kissamos, Loulakaki 13, Lentariana, 73134 Chania, Crete, - - 2014
Subcapsular hematoma of the liver represents an unusual clinical phenomenon in the pregnancy and postpartum period with serious complications in terms of fetal and maternal mortality. Here we report a case of a 32-year-old primiparous female at 36 weeks of gestation, admitted to a maternity ward of a private clinic ...
Haumonte Jean Baptiste JB Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Department of Gynecology and Obstetrics, Gynépole Marseille, Hôpital Nord, Chemin des Bourrely, 13915 Marseille, France ; Aix-Marseille Université, UMR 1076 INSERM, Vascular Research Center of Marseille, 3005 Marseille, - - 2014
The major histocompatibility complex class I related chain (MIC) is a stress-inducible protein modulating the function of immune natural killer (NK) cells, a major leukocyte subset involved in proper trophoblast invasion and spiral artery remodeling. Aim of the study was to evaluate whether upregulation of soluble MIC (sMIC) may reflect ...
Morwood Carrington J CJ Mercy Perinatal Research Centre, Mercy Hospital for Women, Heidelberg, Victoria, Australia; Obstetrics, Nutrition and Endocrinology Group, Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, - - 2014
Spontaneous preterm birth is the leading cause of infant death and of neurological disabilities in survivors. A significant proportion of spontaneous preterm births are associated with infection. Infection activates inflammation which induces a cascade of events that leads to myometrial contractions and rupture of fetal membranes. In non-gestational tissues, the ...
Baeza-Loya Selina - - 2014
Electronic cigarettes (e-cigarettes) are nicotine-delivery devices that are increasingly used, especially by young people. Because e-cigarettes lack many of the substances found in regular tobacco, they are often perceived as a safer smoking alternative, especially in high-risk situations such as pregnancy. However, studies suggest that it is exposure to nicotine ...
Welsh Michelle M School of Life Sciences, West Medical Building, University of Glasgow, Glasgow, - - 2014
Sexual differentiation is a tightly regulated series of events which transform the indifferent gonads and genitalia into sex-specific structures. This is driven by hormones produced by the fetal testes, primarily testosterone (T). However, masculinization of each structure does not occur synchronously and, until recently, it was presumed that androgens also ...
Voltolini Chiara C Department of Molecular and Developmental Medicine, University of Siena, Siena, - - 2014
During pregnancy, the maternal brain drives a series of adaptive mechanisms that are fundamental for allowing fetal growth and development, protecting both mother and fetus from adverse programming and timing of parturition. This neuroendocrine concept is even more complex as fetal brain and placenta also participate as regulators of maternal-placental-fetal ...
Bidwell Gene L GL 3rd Department of Neurology, The University of Mississippi Medical Center Jackson, MS, USA ; Department of Biochemistry, The University of Mississippi Medical Center Jackson, MS, - - 2014
The last several decades have seen intensive research into the molecular mechanisms underlying the symptoms of preeclampsia. While the underlying cause of preeclampsia is believed to be defective placental development and resulting placental ischemia, it is only recently that the links between the ischemic placenta and maternal symptomatic manifestation have ...
Epstein Richard A RA Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, - - 2014
In pregnant women with major depression, the overarching goal of treatment is to achieve or maintain maternal euthymia, thus limiting both maternal and fetal exposure to the harmful effects of untreated or incompletely treated depression. However, the absence of uniformly effective therapies with guaranteed obstetric and fetal safety makes the ...
Habbeddine Mohamed M Laboratory of Inflammation, Gestation and Autoimmunity, Jacques Monod Institute, CNRS and University Paris-Diderot, Paris, - - 2014
Despite much interest in the mechanisms regulating fetal-maternal interactions, information on leukocyte populations and major cytokines present in uterus and placenta remains fragmentary. This report presents a detailed and quantitative study of leukocyte populations at the mouse fetal-maternal interface, including a comparison between pregnancies from syngeneic and allogeneic crosses. Our ...
Wang Hua H Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, Anhui, - - 2014
Lipopolysaccharide (LPS) is associated with adverse developmental outcomes including embryonic resorption, fetal death, congenital teratogenesis and fetal growth retardation. Here, we explored the effects of maternal LPS exposure during pregnancy on testicular development, steroidogenesis and spermatogenesis in male offspring. The pregnant mice were intraperitoneally injected with LPS (50 µg/kg) daily ...
Mulligan Alicia C AC Department of Obstetrics and Gynaecology Christchurch Women's Hospital, Canterbury District Health Board, Private Bag 4711, Christchurch, New Zealand. - - 2014
In 2010, the National Screening Unit of the Ministry of Health launched 'Antenatal Screening for Down syndrome and other conditions'. Our aim was to assess the local impact of the new screening process on the number and outcomes of women attending a south island Fetal Medicine Centre. Retrospective audit; two ...
Soh Shu-E SE Saw Swee Hock School of Public Health, National University of Singapore, Singapore, - - 2014
The dramatic emergence of noncommunicable diseases (NCD) in Asia, albeit with ethnic variation, has coincided with the rapid socioeconomic and nutritional transition taking place in the region, with the prevalence of diabetes rising 5-fold in Singapore in less than 4 decades. The Growing Up in Singapore Towards healthy Outcomes (GUSTO) ...
Hayes Louise L Institute of Health and Society, Newcastle University, Newcastle upon Tyne, - - 2014
Obesity in pregnancy is associated with fetal macrosomia, a raised neonatal fat mass and an increased risk of obesity and poor metabolic health in childhood which persists into adulthood. The offspring of obese women are more likely to be obese than the offspring of lean women when they become pregnant ...
Larqué Elvira E Department of Physiology, University of Murcia, Murcia, - - 2014
The functionality of the placenta may affect neonatal adiposity and fetal levels of key nutrients such as long-chain polyunsaturated fatty acids. Fetal macrosomia and its complications may occur even in adequately controlled gestational diabetic (GDM) mothers, suggesting that maternal glycemia is not the only determinant of fetal glycemic status and ...
Strøm Marin M Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, - - 2014
Vitamin D is obtained from dietary sources and synthesized in the skin during exposure to ultraviolet B radiation in sunlight. During pregnancy, vitamin D is transported from mother to fetus through the placenta in the form of 25-hydroxyvitamin D [25(OH)D]. There is evidence that vitamin D influences neuronal differentiation, endocrine ...
Wang Xiaogang X Department of Mathematics and Statistics, York University, Toronto, Ontario, - - 2014
Severe fetal acidemia during labour can result in life-lasting neurological deficits, but the timely detection of this condition is often not possible. This is because the positive predictive value (PPV) of fetal heart rate (FHR) monitoring, the mainstay of fetal health surveillance during labour, to detect concerning fetal acidemia is ...
Glass Leila L Center for Behavioral Teratology, San Diego State University, San Diego, CA, - - 2014
Alcohol consumption during pregnancy can have deleterious consequences for the fetus, including changes in central nervous system development leading to permanent neurologic alterations and cognitive and behavioral deficits. Individuals affected by prenatal alcohol exposure, including those with and without fetal alcohol syndrome, are identified under the umbrella of fetal alcohol ...
Quigley James J Manchester Royal Infirmary, Manchester, - - 2014
We describe a rare but sinister presentation of fatigue and dyspnoea in a 39-year-old woman at 16 weeks gestation. Blood tests and bone marrow aspirate confirmed the diagnosis of multiple myeloma. The patient was managed expectantly during pregnancy with plasma exchange and blood transfusion. The pregnancy continued without event; labour was ...
di Liberto Alexander A Department of Obstetrics and Gynecology, Leverkusen Municipal Hospital, Leverkusen, - - 2014
Serious fetal malformations and/or chromosome aberrations detected by modern diagnostic tools in early pregnancy require discussions on induced abortion with pregnant women. Competent counseling includes prediction of the time needed for the whole abortion process. In an attempt to refine our predictions, we evaluated the impact of 11 medical history ...
Brett Kendra Elizabeth KE Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Rd., Ottawa, ON K1H 8L1, Canada. - - 2014
Appropriate in utero growth is essential for offspring development and is a critical contributor to long-term health. Fetal growth is largely dictated by the availability of nutrients in maternal circulation and the ability of these nutrients to be transported into fetal circulation via the placenta. Substrate flux across placental gradients ...
Johnston Jill E JE Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of - - 2014
Cadmium (Cd) is a ubiquitous environmental contaminant, a known carcinogen, and understudied as a developmental toxicant. In the present study, we examined the relationships between Cd levels during pregnancy and infant birth outcomes in a prospective pregnancy cohort in Durham, North Carolina. The study participants (n = 1027) had a mean Cd ...
Jiang Chuen-Bin CB Department of Pediatrics, Taipei Mackay Memorial Hospital, Taipei, Taiwan; Mackay Junior College of Medicine, Nursing, and Management, Taipei, - - 2014
Mercury (Hg), lead (Pb), cadmium (Cd), and arsenic (As) are recognized neurotoxins in children that particularly affect neurodevelopment and intellectual performance. Based on the hypothesis that the fetal basis of adult disease is fetal toxic exposure that results in adverse outcomes in adulthood, we explored the concentrations of key neurotoxins ...
Huang Ke K Department of Gynecology and Obstetrics, The PLA General Hospitaln Beijing City, - - 2014
Advanced abdominal pregnancy is rare. The low incidence, high misdiagnosis rate, and lack of specific clinical signs and symptoms explain the fact that there are no standard diagnostic and treatment options available for advanced abdominal pregnancy. We managed a case of abdominal pregnancy in a woman who was pregnant for ...
Hichijo Atsuko A 0000-0002-1293-0614 Department of Obstetrics and Gynecology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, - - 2014
Parvovirus B19 is a well-established cause of fetal anemia and nonimmune fetal hydrops in pregnancy. Fetal parvovirus infection can cause severe destruction of erythroid progenitor cells, resulting in fetal anemia, hydrops, and intrauterine death. However, viral myocarditis with subsequent heart failure is another possible mechanism for hydrops formation as viral ...
Dong Yupeng Y Advanced Interdisciplinary Biomedical Engineering, Tohoku University Graduate School of Medicine, Sendai, - - 2014
Ischemic reperfusion (IR) during the perinatal period is a known causative factor of fetal brain damage. So far, both morphologic and histologic evidence has shown that fetal brain damage can be observed only several hours to days after an IR insult has occurred. Therefore, to prevent fetal brain damage under ...
Chang Jen Jen JJ Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, St. Louis, Missouri, United States of - - 2014
To investigate the association between cigarette use during pregnancy and pregnancy-induced hypertension/preeclampsia/eclampsia (PIH) by maternal race/ethnicity and age. This retrospective cohort study was based on the U.S. 2010 natality data. Our study sample included U.S. women who delivered singleton pregnancies between 20 and 44 weeks of gestation without major fetal ...
Saha Soma - - 2014
The aim was to study morphometry, site of umbilical cord insertion and histological changes in placentae of women with gestational diabetes mellitus and compare the results with those of normal pregnancies and observe the perinatal outcome. It was an observational, correlational study of 130 placenta specimens collected from labour room ...
Troyano-Luque Juan J 0000-0002-5160-9583 Department of Obstetrics and Gynecology, Ultrasound and Fetal Medicine Unit, University Hospital of Canary Islands, Ctra. Ofra, s/n, Santa Cruz de Tenerife, 38320 San Cristóbal de La Laguna, - - 2014
The aims of this study were to present and discuss ultrasound findings of prenatal fetal cholelithiasis in two cases with different etiology and evolution. Case 1: a pregnant woman from sub-Saharan Africa, suffering from Lyme disease, was treated with ceftriaxone sodium. Six weeks later, biliary sludge associated with polyhydramnios was ...
Noureldeen Amani F H AF Biochemistry Department, Faculty of Science, King Abdul Aziz University, Jeddah, Saudi Arabia ; Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, - - 2014
Gestational diabetes mellitus (GDM) is a common medical complication associated with pregnancy. The present study evaluates the changes in maternal adipocytokines (leptin, adiponectin, resistin, visfatin and tumor necrosis factor-alpha; TNF-α) in pregnancy complicated with GDM compared to normal pregnancy at 2nd and 3rd trimesters. The study included total number of ...
Farhadifar Fariba F Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran ; Obstetrics and Gynecology, Kurdistan Research Center for Social Determinants of Health, Kurdistan University of Medical Sciences, Sanandaj, - - 2014
Some degree rotation of the gravid uterus in the third trimester of pregnancy is not an abnormal finding. However, extreme uterine torsion of 180° around its cervical junction is a relatively rare event in obstetrical practice. We report here such a case that detected at laparotomy for an emergency cesarean ...
Piccardi Laura - - 2013
Discordant findings have been reported about the change in pregnant women's cognitive test performance. Visuo-spatial abilities, which are crucial in terrestrial/flight navigation, could be influenced by hormonal variations. A 32-yr-old Italian Air Force pilot underwent a 2-D Mental Rotation Task (MRT) and hormonal assessment in the second trimester of pregnancy ...
Stær-Jensen Jette - - 2013
To investigate whether pregnancy affects levator hiatus dimensions and the position and mobility of the bladder neck and the levator ani muscle in nulliparous pregnant women. In the present study, 274 nulliparous pregnant women were examined at 21 weeks and 37 weeks of gestation using three-dimensional and four-dimensional transperineal ultrasonography ...
Borges Kevin Joseph Jerome - - 2013
Pregnancy induced hypertension results from defective trophoblast invasion and increased umbilical artery resistance which in turn results in decreased blood supply to the placenta and hence to the foetus. This arterial resistance varies in different cases of PIH thus causing variable effects on placenta and foetus. The objective of this ...
Kamalifard Mahin M Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, - - 2013
Fetal movement counting is a method used by mother to quantify her baby's movements. However, the optimal number of movements and the ideal duration of counting them have not been recognized. The aim of this study was to determine the diagnostic value of the two common fetal movements counting methods ...
McCrory Jean L - - 2013
Pregnant women experience numerous physical alterations during pregnancy which may place them at an increased risk of falls. The purpose of this study was to examine ground reaction forces (GRFs) during staircase locomotion in pregnant and non-pregnant women. METHODS: Data were collected on 29 pregnant women in their second and ...
Demirhan Osman O Department of Medical Biology and Genetics, Faculty of Medicine, University of Çukurova, Adana, - - 2013
Fetal cells can enter maternal blood during pregnancy but whether they can also cross the blood-brain barrier to enter the maternal brain remains poorly understood. Previous results suggest that fetal cells are summoned to repair damage to the mother's brain. If this is confirmed, it would open up new and ...
Ocal Işil - - 2013
The present study was aimed at determining the effective doses of Dexmedetomidine (Dex) involved in amplitude of contraction-force and frequency of uterine rings in pregnancy terms of rats. All experiments involving animal subjects were carried out with the approval of animal care and use Ethical Committee of Cukurova University. Experiments ...
Zuzek Crystal - - 2013
In this year&#39;s legislative session, lawmakers passed Senate Bill 495, aimed at helping physicians and public health officials reduce the tragic toll of maternal death in the state. It creates the Maternal Mortality and Morbidity Review Task Force under the Texas Department of State Health Services. The task force will ...
Maruthini Deivanayagam D The Leeds Centre for Reproductive Medicine, Seacroft Hospital, Leeds LS14 6UH, - - 2013
We present a case of recurrent ruptured right cornual ectopic pregnancies conceived after IVF. Following the second episode, a sonohysterography was undertaken to identify possible areas of scar weakness that may rupture with uterine distension in a future pregnancy. The scan revealed asymmetrical muscle thickness in the cornual regions, the ...
Ghaffari Firouzeh F Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, - - 2013
The aim of this study was to compare the effects of easy and difficult embryo transfers (ET) on implantation and pregnancy rates. In this prospective study, we analyzed the results of 706 ET procedures over a 12-month period. An easy ET was defined as a transfer that occurred without the ...
Ghajar K - - 2012
Introduction: The purpose of this study was to investigate the effect of pregnancy on orthodontic tooth movement in Wistar rats. Material and Methods: Forty eight female three-month old Wistar rats with an average weight of 250±25 gr were selected and randomly divided into two experimental (pregnant) and control groups (non-pregnant). ...
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