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Results 301 - 350 of 1081
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Radunovic Nebojsa N Faculty of Medicine, University of Belgrade , Belgrade , Serbia - - 2014
Abstract Objective: To measure fetal and maternal plasma homocysteine (Hcy) concentrations in uncomplicated pregnancies. Methods: Paired maternal venous and fetal umbilical cord blood (n = 81) samples were evaluated for plasma Hcy and vitamin B12 levels, in addition to eight neonatal umbilical cord blood samples obtained immediately following delivery. Results: Both fetal ...
Kacerovsky Marian M Biomedical Research Center, University Hospital Hradec Kralove , Hradec Kralove , Czech Republic - - 2014
Abstract Objective: To determine amniotic fluid total antioxidant capacity (TAC), ferric-reducing antioxidant power (FRAP) and thiobarbituric acid-reacting substances (TBARS), markers of oxidative stress, in pregnancies complicated by preterm prelabor rupture of membranes (pPROM) and their correlation to microbial invasion of the amniotic cavity (MIAC) and/or histological chorioamnionitis (HCA). Methods: One-hundred ...
Svensson Elisabeth E From the aDepartment of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University, Denmark; bResearch Triangle Institute, Research Triangle Park, NC; and cDepartment of Epidemiology, Boston University School of Public Health, Boston, - - 2014
Prenatal termination of pregnancy may underestimate risks or cause bias in epidemiological studies of birth defects if such studies measure only defects diagnosed postnatally. We aimed to estimate the proportion of all fetuses with birth defects terminated in the second trimester of pregnancy-overall and for specific defects. The study comprised ...
Salihu Hamisu M HM Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL; 13201 Bruce B. Downs Blvd., MDC56, Tampa, FL, USA 33612; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL; 2 Tampa General Circle, 6th Floor, Tampa, FL, USA 33606. Electronic address: - - 2014
We sought to investigate whether maternal smoking during pregnancy affects telomere length of the fetus. Pregnant women were recruited upon hospital admission at delivery. A self-report questionnaire and salivary cotinine test were used to confirm tobacco exposure. Neonatal umbilical cord blood samples were collected and genomic DNA was isolated from ...
Verspyck Eric E Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France. Electronic address: - - 2014
To compare maternal outcomes after transection and after avoiding incision of the anterior placenta previa during cesarean delivery. In a retrospective study, records were reviewed for women who had anterior placenta previa and delivered by cesarean after 24weeks of pregnancy at a tertiary center in Rouen, France. During period A ...
Lurie Samuel S Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: - - 2014
To compare maternal outcomes when cesarean sections were performed in the second stage of labor to those performed in the first stage of labor by indication for the operation. This is a retrospective cohort (n=383) of term parturient women who underwent primary cesarean section during active labor. Cases were drawn ...
van Veelen G A GA Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht, Utrecht, The - - 2014
To determine the association between levator hiatal dimensions using transperineal ultrasound in women during their first pregnancy and mode of delivery, stratified for the indication for intervention. In this prospective observational study, 280 nulliparous pregnant women were invited for transperineal ultrasound examination at 12 weeks' gestation and 36 weeks' gestation. ...
Ruano Rodrigo R Department of Obstetrics and Gynecology, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Fetal Center - Texas Children's Hospital Pavilion for Women, Houston, Texas, United - - 2014
To evaluate the efficacy of fetal intervention (fetal cystoscopy and vesico-amniotic shunt) in the treatment of severe lower urinary obstruction (LUTO). This is a retrospective study of a cohort of 111 fetuses with severe LUTO in two centers between January 1990 and August 2013. Fetuses were divided into 3 groups: ...
Li Na N Department of Obstetrics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, - - 2014
To assess the role of the placental arterial Doppler examination at 23-24 gestational weeks for predicting adverse perinatal outcome in high-risk pregnancies. Retrospective register study. Skåne University Hospital in Malmö. 645 women with high-risk pregnancies, without fetal malformations or chromosomal abnormalities. Methods: Placental (uterine and umbilical artery) Doppler ultrasound examination ...
Hillman Sarah C SC College of Women's and Children's Health & School of Clinical and Experimental Medicine, College of Medicine and Dentistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Fetal Medicine Centre, Birmingham Women's Foundation Trust, Edgbaston, Birmingham, - - 2014
Structural fetal anomalies identified on prenatal ultrasound occur in 3% of pregnancies and a genetic diagnosis can help inform the pregnancy management and future reproductive decisions. The science behind prenatal genetic diagnostics is moving at a rapid pace. Conventional G-band karyotyping is being replaced by chromosome microarray analysis (CMA), which ...
Watts D Heather DH 1Office of the Global AIDS Coordinator, U.S. Department of State, Washington, DC, 2University of Southern California School of Medicine, Department of Obstetrics and Gynecology, Los Angeles, CA, 3University of California, San Diego School of Medicine and Skaggs School of Pharmacy & Pharmaceutical Sciences, San Diego, CA, 4Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA, 5Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, 6Department of Clinical Pharmacy, Drug Research Unit, University of California, San Francisco, San Francisco, CA, 7HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, RS, Brazil, 8Boston Children's Hospital and Harvard Medical School, Boston, MA, 9Social and Scientific Systems, Inc, Silver Spring, MD, 10NIAID, Bethesda, MD, 11Boston University School of Medicine, Boston, - - 2014
We evaluated the pharmacokinetics (pk) of raltegravir in HIV-infected women during pregnancy and postpartum. IMPAACT 1026s is an on-going prospective study of antiretroviral pk during pregnancy (NCT00042289). Women receiving 400 mg raltegravir twice daily in combination antiretroviral therapy had intensive steady state 12-hour pk profiles performed during pregnancy and at ...
Bradford Billie - - 2014
Maternal perception of decreased fetal movements is a specific indicator of fetal compromise, notably in the context of poor fetal growth. There is currently no agreed numerical definition of decreased fetal movements, with the subjective perception of a decrease on the part of the mother being the most significant definition ...
Kemp Matthew W MW School of Women's and Infants' Health, The University of Western Australia, Perth, Western Australia, Australia. - - 2014
Treatment of intrauterine infection is likely key to preventing a significant proportion of preterm deliveries before 32 weeks' gestation. Azithromycin (AZ) may be an effective antimicrobial in pregnancy; however, few gestation-appropriate data are available to inform the design of AZ-based treatment regimens in early pregnancy. We aimed to determine whether ...
Rohilla Minakshi M Department of Obstetrics and Gynecology, PGIMER, Chandigarh (U.T.), 160012, India, - - 2014
Fetal destructive operation is a vanishing art today. In an era of increasing cesarean deliveries it has become a historic event. Incidence of destructive operation has varied from various Indian hospitals 0.09-0.28 %. Evisceration is one of the rarest of all destructive operations, performed in cases of cephalopelvic disproportion with large ...
Sheikh Mahdi - - 2014
Maternal counting of fetal movement is a popular and valuable screening tool of fetal wellbeing, however it is still not known what percentage of healthy pregnant women who gave birth to healthy term newborns had experienced decreased fetal movements during gestation and what maternal and fetal factors are associated with ...
Jang Y D YD Department of Animal and Food Sciences, University of Kentucky, Lexington - - 2014
To investigate the effect of intrauterine positions on fetal growth throughout gestation, data from a total of 65 gilts (n = 784 fetuses) that were slaughtered at assigned days of gestation (d 43, 58, 73, 91, 101, and 108) on a project to evaluate fetal mineral deposition were used. Placenta ...
Franco D J DJ Department of Agriculture, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta T6G 2P5, - - 2014
Amino acid requirements of sows may change from early to late gestation due to the accelerated growth of products of conception conceptus after d 70 of pregnancy. The objective of this study was to determine the Trp requirement, Phe kinetics and energy expenditure in early (d 35 to 53) and ...
Yang Hyun H Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of - - 2014
Preeclampsia is a pregnancy-specific disorder characterized by de novo development of concurrent hypertension, proteinuria, and placental oxidative stress. During the last trimester of gestation, maternal-to-fetal transport of minerals is dramatically increased and becomes tightly mediated by ion channels that are highly permeable to various divalent cations, such as Ca(2+) , ...
Skråstad Ragnhild Bergene RB Department of Laboratory Medicine Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; National Center for Fetal Medicine, Department of Obstetrics and Gynecology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, - - 2014
To investigate the prediction of preeclampsia and gestational hypertension with the use of maternal characteristics, mean arterial pressure (MAP), uterine artery pulsatility index (UtAPI), pregnancy-associated plasma protein-A (PAPP-A) and placental growth factor (PlGF) at gestational weeks 11-13 in a Scandinavian population with a medium to high beforehand risk for developing ...
Lee Bang Hyun BH Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National - - 2014
More than 75% of pregnant women consume drinks containing caffeine such as coffee, tea, and soft drinks (1) Although many studies have reported that caffeine induces miscarriage, congenital malformations, fetal growth retardation, or preterm birth, studies examining the mechanism by which caffeine functions during pregnancy have been rarely reported. Serum ...
Wang Li-Qin LQ Nursing Department, Xi'an Medical College, - - 2014
To examine the expression of CD200 and its receptor (CD200R) in human chorionic villi during the first trimester of normal pregnancy and early spontaneous abortion (ESA). Prospective study. Expression of CD200 and CD200R in the chorionic villi was determined using SP immunohistochemistry, confocal laser scanning microscopy and real-time PCR. 35 ...
Visser Gerard H A GH Department of Obstetrics, University Medical Center, Utrecht, The Netherlands. Electronic address: - - 2014
Pregnancy in women with diabetes remains complicated despite improvements in glucose control. This seems mainly due to the fact that normoglycemia is still outside of reach. Congenital malformations are already significantly increased in the case of HbA1c values of 2-4SD above the mean, and fetal macrosomia is increasing in incidence. ...
Pillar Nir N Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, - - 2014
Great obstetrical syndromes is a collective name for several complications of pregnancy that affect >15% of pregnancies. They may confer adverse pregnancy outcomes and maternal and fetal morbidity, and require close medical monitoring and treatment. The etiology, pathogenesis, and outcome of these syndromes are obscure in the majority of cases. ...
Hod Moshe M Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel. Electronic address: - - 2014
Maternal-fetal medicine (MFM) is a multidisciplinary subspecialty dedicated to optimization of pregnancy and perinatal outcomes. MFM utilizes novel technologies for diagnostics and treatments in order to optimize obstetrical care and pregnancy outcome. Although defined as maternal and fetal medicine, originally aiming to equally address fetal and/or maternal issues, in reality ...
Solt Ido I Division of Maternal-Fetal Medicine Service, Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel; The Rappaport Faculty of Medicine, Technion, Haifa, Israel. Electronic address: - - 2014
The emergence of the concept of the microbiome, together with the development of molecular-based techniques, particularly polymerase chain reaction (PCR) amplification using the 16S ribosomal RNA (rRNA) gene, has dramatically increased the detection of microorganisms, the number of known species, and the understanding of bacterial communities that are relevant to ...
Dessì Angelica A Neonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, Azienda Ospedaliera Universitaria, University of Cagliari, SS 554 09042, Cagliari, Italy. Electronic address: - - 2014
Gestational diabetes mellitus, intrauterine growth restriction, and preeclamptic toxemia are common pregnancy complications that can have detrimental effects on morbidity and mortality of the mother and fetus as well as long-term health outcomes. Although they are distinct conditions, they may occur together and are often considered together as they share ...
Murugappan Gayathree G Department of Reproductive Endocrinology and Infertility, Stanford Hospital & Clinics, Stanford, California. Electronic address: - - 2014
To demonstrate a technique for separation of miscarriage tissue from maternal decidua to reduce maternal cell contamination for chromosome analysis. Retrospective. University-based infertility center. Not applicable. Retrospective collection of de-identified images and video from manual vacuum aspiration (MVA) performed after first-trimester pregnancy losses. This project was exempt from institutional review ...
Koren Gideon G Motherisk Program, The Hospital for Sick Children and University of - - 2014
Presently, 97.7 % of prescriptions for the treatment of nausea and vomiting in pregnancy (NVP) in the USA are with medications not labeled for use in pregnancy, not indicated for NVP, and not classified as safe in pregnancy by the FDA. The use of ondansetron for NVP has increased from ...
Chang Kenneth Tou-En KT Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore; Duke-NUS Graduate Medical School, Singapore. Electronic address: - - 2014
Formal examination of the placenta may provide valuable information to the clinicians, family, and court of law in cases of adverse pregnancy outcome when litigation is initiated. Placental examination contributes towards the identification of specific intrinsic or secondary placental lesions, and understanding the nature of the intrauterine environment. This article ...
Gardosi J J Perinatal Institute, Birmingham B15 3BU, UK. Electronic address: - - 2014
Most stillbirths used to be categorized as 'unexplained' and were considered, by implication, unavoidable. Recent evidence indicates that they represent a combined challenge for public health and for clinical services. Independent case reviews have found that many deaths are associated with a failure to recognize risk factors and to afford ...
Gabbay-Benziv Rinat R Department of Obstetrics, Gynaecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; Beilinson Hospital for Women, Rabin Medical Centre, PetachTikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Gestational diabetes mellitus (GDM)-associated fetal and neonatal adverse outcome results from the metabolic milieu projected on the fetus via the placental interface. Therefore, it can be considered to be one of the great obstetrical syndromes. Placentas from GDM pregnancies differ from nondiabetic pregnancies by an increased placental to fetal ratio ...
Oberbeck Nina N MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, - - 2014
Maternal metabolism provides essential nutrients to enable embryonic development. However, both mother and embryo produce reactive metabolites that can damage DNA. Here we discover how the embryo is protected from these genotoxins. Pregnant mice lacking Aldh2, a key enzyme that detoxifies reactive aldehydes, cannot support the development of embryos lacking the Fanconi anemia ...
Thuring Ann A Department of Clinical Sciences Lund, Obstetrics and Gynecology, Lund University, Lund, - - 2014
Analysis of umbilical artery flow velocity waveforms characterized by pulsatility index (PI) is used to evaluate fetoplacental circulation in high-risk pregnancies. However, an experienced sonographer may be able to further differentiate between various timbres of Doppler audio signals. Recently, we have developed a method for objective audio signal characterization; the ...
Desoye Gernot G Department of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria. Electronic address: - - 2014
Recent studies have established that the neonate born to a pregnancy with maternal diabetes or obesity ('diabesity') is characterized by increased fat accumulation. The neonatal fat is the result of triglyceride synthesis and deposition stimulated by elevated fetal insulin levels combined with insulin's mitogenic activity directly stimulating the growth of ...
Willis Kent K Our Lady of the Lake Regional Medical Center, Baton Rouge, LA, USA. Electronic address: - - 2014
The global obesity epidemic is changing the face of maternal-fetal medicine. One in five women is obese at time of conception, and increasing numbers of parturients have undergone bariatric surgery. Recent publication of large, population-based studies and comparison studies of preoperative and post-operative pregnancies have highlighted new risks and benefits ...
Aaronson Jaime J Division of Obstetric Anesthesiology, Department of Anesthesiology, Columbia University, 630 W 168th St, P & S Box 46, New York, NY, - - 2014
The scope of obstetric anesthesia practice ranges far beyond the delivery of care to women for vaginal and cesarean deliveries. Increasingly, obstetric anesthesiologists are involved in the management of anesthetics for new procedures and for new indications. Anesthesia is frequently needed for maternal procedures, as well as fetal procedures, and ...
Zhou F F Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan 610041, - - 2014
Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse pregnancy outcomes. Fetal distress in ICP is an acute process, and the abnormal expression of placental local vasodilatory factors play an essential role. Urocortin (UCN) exhibits a powerful concentration-dependent vasodilatation effect in the utero-placental-fetal unit. Our study ...
Liat Salzer S Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Obesity is a rising global epidemic. Obesity during pregnancy is associated with increased maternal and fetal risks, which is inversely correlated with the severity level of obesity. Other comorbidities are common (diabetes mellitus, hypertensive disorders, etc.) and contribute to an even increased risk. Maternal obesity during pregnancy contributes also to ...
Papachatzi Eleni - - 2014
Abstract Objective: Pre- or early-pregnancy obesity carries significant health implications. This retrospective cohort study investigates the association between pre- or early-pregnancy body mass index (BMI) and the risk of fetal and neonatal death in pregnancies implicated by obesity in a Mediterranean country. Study design: Data on pregnancies delivered during 2003-2008 ...
Gizzo Salvatore - - 2014
Abstract One of the most frequent causes of maternal and perinatal morbidity is represented by hypertensive disorders during pregnancy. Women at high risk must be subjected to a more intensive antenatal surveillance and prophylactic treatments. Many genetic risk factors, clinical features and biomarkers have been proposed but none of these ...
Seidmann L L Institute of Pathology, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany. Electronic address: - - 2014
Idiopathic immaturity is one of the main reasons for latent placental insufficiency and antenatal hypoxia. Postnatal identification of the immature placental phenotype may help early stratification of a heterogeneous population of newborns and individually identify risk of disease in the immediate postnatal life. The aim of the study was to ...
Munnangi S S Department of Pharmaceutical Sciences, St. John's University, Queens, NY, - - 2014
In an effort to improve prenatal screening for Trisomy 21, we evaluated pregnancy associated plasma protein-A2 (PAPP-A2) as a potential novel second trimester biomarker for Trisomy 21. Trisomy 21 and normal control mid-trimester placental samples were subjected to quantitative rt PCR analysis of seven genes we had previously found to ...
Coscia Lisa A LA National Transplantation Pregnancy Registry (NTPR), Gift of Life Institute, 401 N. 3rd Street, Philadelphia, PA 19123, USA. Electronic address: - - 2014
Successful pregnancies have been reported in all types of solid-organ transplant recipients on a variety of immunosuppressive regimens. Immunosuppression is essential to maintain the transplanted organ and maternal health, thus the safety of these medications continues to be studied. This article reviews information in the literature and data from the ...
Yao Youli - - 2014
Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream effects on endocrine, metabolic and behavioural manifestations of PTB possibly via microRNA (miRNA) regulation. Pregnant dams ...
Junaid T O TO Maternal and Fetal Health Research Centre, Institute of Human Development, Manchester Academic Health Science Centre, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, University of Manchester, Manchester M13 9WL, UK. Electronic address: - - 2014
Placental functional impairment in pregnancies with fetal growth restriction (FGR) can arise from fetoplacental vascular abnormalities. We aimed to compare the micro and macrovasculature of placentas from normal pregnancies with those showing late onset FGR. Placental arterial casts (n = 12 normal, 6 FGR) were prepared. Chorionic arterial number and inter-branch length ...
Simják Patrik - - 2014
Abstract Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder of pregnancy. Diagnosis is based on the clinical picture, particularly the presence of pruritus with a deterioration of liver function tests, and typically elevated serum levels of total bile acids. ICP manifests in the second half of pregnancy, ...
Iciek R R Department of Obstetrics and Women's Diseases, Poznan University of Medical Sciences, Poznan, Poland. - - 2014
Type 1 diabetes mellitus (T1DM) is still associated with increased risk of severe maternal and foetal complications but their pathomechanism remains unclear. we investigated the possible role of placental vascular endothelial growth factor (VEGF) and VEGF single nucleotide polymorphisms (SNP) in foetal development in T1DM pregnancies. Sixty seven pregnant women ...
Cetković Aleksandar - - 2014
Pregnancies complicated with antiphospholipd syndrome are associated with the increased perinatal mortality and morbidity. The aim of this study was to assess perinatal outcome in pregnancies with primary antiphospholipd syndrome. This prospective study evaluated perinatal outcome in 25 pregnant women with antiphospholipid syndrome. After establishing vital pregnancy all the patients ...
Aydogan P P Department of Obstetrics and Gynecology, Isparta Maternity Hospital, Isparta, Turkey. - - 2014
The underlying inflammation of endometrium may impede normal implantation of placenta during pregnancy. Our objective is to show cervical colonization of ureaplasma and/or mycoplasma as a marker of endometritis in pregnancies complicated with placenta previa that can be a risk factor for placenta accreta and peripartum hemorrhage. Cervical cultures for ...
Toptas Tayfun - - 2014
No systematic empirical research exists addressing the question of optimal pregnancy termination method in second trimester pregnancies. The purpose of this study was to determine the efficacy and safety of intravaginal misoprostol and extraamniotic Foley catheter combination for second trimester pregnancy termination. A single center observational study was conducted in ...
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