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Jang Y D YD Department of Animal and Food Sciences, University of Kentucky, Lexington - - 2014
To investigate the effect of intrauterine positions on fetal growth throughout gestation, data from a total of 65 gilts (n = 784 fetuses) that were slaughtered at assigned days of gestation (d 43, 58, 73, 91, 101, and 108) on a project to evaluate fetal mineral deposition were used. Placenta ...
Franco D J DJ Department of Agriculture, Food and Nutritional Sciences, University of Alberta, Edmonton, Alberta T6G 2P5, - - 2014
Amino acid requirements of sows may change from early to late gestation due to the accelerated growth of products of conception conceptus after d 70 of pregnancy. The objective of this study was to determine the Trp requirement, Phe kinetics and energy expenditure in early (d 35 to 53) and ...
Yang Hyun H Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of - - 2014
Preeclampsia is a pregnancy-specific disorder characterized by de novo development of concurrent hypertension, proteinuria, and placental oxidative stress. During the last trimester of gestation, maternal-to-fetal transport of minerals is dramatically increased and becomes tightly mediated by ion channels that are highly permeable to various divalent cations, such as Ca(2+) , ...
Skråstad Ragnhild Bergene RB Department of Laboratory Medicine Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; National Center for Fetal Medicine, Department of Obstetrics and Gynecology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, - - 2014
To investigate the prediction of preeclampsia and gestational hypertension with the use of maternal characteristics, mean arterial pressure (MAP), uterine artery pulsatility index (UtAPI), pregnancy-associated plasma protein-A (PAPP-A) and placental growth factor (PlGF) at gestational weeks 11-13 in a Scandinavian population with a medium to high beforehand risk for developing ...
Lee Bang Hyun BH Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National - - 2014
More than 75% of pregnant women consume drinks containing caffeine such as coffee, tea, and soft drinks (1) Although many studies have reported that caffeine induces miscarriage, congenital malformations, fetal growth retardation, or preterm birth, studies examining the mechanism by which caffeine functions during pregnancy have been rarely reported. Serum ...
Wang Li-Qin LQ Nursing Department, Xi'an Medical College, - - 2014
To examine the expression of CD200 and its receptor (CD200R) in human chorionic villi during the first trimester of normal pregnancy and early spontaneous abortion (ESA). Prospective study. Expression of CD200 and CD200R in the chorionic villi was determined using SP immunohistochemistry, confocal laser scanning microscopy and real-time PCR. 35 ...
Visser Gerard H A GH Department of Obstetrics, University Medical Center, Utrecht, The Netherlands. Electronic address: - - 2014
Pregnancy in women with diabetes remains complicated despite improvements in glucose control. This seems mainly due to the fact that normoglycemia is still outside of reach. Congenital malformations are already significantly increased in the case of HbA1c values of 2-4SD above the mean, and fetal macrosomia is increasing in incidence. ...
Pillar Nir N Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, - - 2014
Great obstetrical syndromes is a collective name for several complications of pregnancy that affect >15% of pregnancies. They may confer adverse pregnancy outcomes and maternal and fetal morbidity, and require close medical monitoring and treatment. The etiology, pathogenesis, and outcome of these syndromes are obscure in the majority of cases. ...
Hod Moshe M Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel. Electronic address: - - 2014
Maternal-fetal medicine (MFM) is a multidisciplinary subspecialty dedicated to optimization of pregnancy and perinatal outcomes. MFM utilizes novel technologies for diagnostics and treatments in order to optimize obstetrical care and pregnancy outcome. Although defined as maternal and fetal medicine, originally aiming to equally address fetal and/or maternal issues, in reality ...
Solt Ido I Division of Maternal-Fetal Medicine Service, Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel; The Rappaport Faculty of Medicine, Technion, Haifa, Israel. Electronic address: - - 2014
The emergence of the concept of the microbiome, together with the development of molecular-based techniques, particularly polymerase chain reaction (PCR) amplification using the 16S ribosomal RNA (rRNA) gene, has dramatically increased the detection of microorganisms, the number of known species, and the understanding of bacterial communities that are relevant to ...
Murugappan Gayathree G Department of Reproductive Endocrinology and Infertility, Stanford Hospital & Clinics, Stanford, California. Electronic address: - - 2014
To demonstrate a technique for separation of miscarriage tissue from maternal decidua to reduce maternal cell contamination for chromosome analysis. Retrospective. University-based infertility center. Not applicable. Retrospective collection of de-identified images and video from manual vacuum aspiration (MVA) performed after first-trimester pregnancy losses. This project was exempt from institutional review ...
Koren Gideon G Motherisk Program, The Hospital for Sick Children and University of - - 2014
Presently, 97.7 % of prescriptions for the treatment of nausea and vomiting in pregnancy (NVP) in the USA are with medications not labeled for use in pregnancy, not indicated for NVP, and not classified as safe in pregnancy by the FDA. The use of ondansetron for NVP has increased from ...
Chang Kenneth Tou-En KT Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore; Duke-NUS Graduate Medical School, Singapore. Electronic address: - - 2014
Formal examination of the placenta may provide valuable information to the clinicians, family, and court of law in cases of adverse pregnancy outcome when litigation is initiated. Placental examination contributes towards the identification of specific intrinsic or secondary placental lesions, and understanding the nature of the intrauterine environment. This article ...
Gardosi J J Perinatal Institute, Birmingham B15 3BU, UK. Electronic address: - - 2014
Most stillbirths used to be categorized as 'unexplained' and were considered, by implication, unavoidable. Recent evidence indicates that they represent a combined challenge for public health and for clinical services. Independent case reviews have found that many deaths are associated with a failure to recognize risk factors and to afford ...
Oberbeck Nina N MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, - - 2014
Maternal metabolism provides essential nutrients to enable embryonic development. However, both mother and embryo produce reactive metabolites that can damage DNA. Here we discover how the embryo is protected from these genotoxins. Pregnant mice lacking Aldh2, a key enzyme that detoxifies reactive aldehydes, cannot support the development of embryos lacking the Fanconi anemia ...
Gabbay-Benziv Rinat R Department of Obstetrics, Gynaecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; Beilinson Hospital for Women, Rabin Medical Centre, PetachTikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Gestational diabetes mellitus (GDM)-associated fetal and neonatal adverse outcome results from the metabolic milieu projected on the fetus via the placental interface. Therefore, it can be considered to be one of the great obstetrical syndromes. Placentas from GDM pregnancies differ from nondiabetic pregnancies by an increased placental to fetal ratio ...
Thuring Ann A Department of Clinical Sciences Lund, Obstetrics and Gynecology, Lund University, Lund, - - 2014
Analysis of umbilical artery flow velocity waveforms characterized by pulsatility index (PI) is used to evaluate fetoplacental circulation in high-risk pregnancies. However, an experienced sonographer may be able to further differentiate between various timbres of Doppler audio signals. Recently, we have developed a method for objective audio signal characterization; the ...
Desoye Gernot G Department of Obstetrics and Gynaecology, Medical University of Graz, Graz, Austria. Electronic address: - - 2014
Recent studies have established that the neonate born to a pregnancy with maternal diabetes or obesity ('diabesity') is characterized by increased fat accumulation. The neonatal fat is the result of triglyceride synthesis and deposition stimulated by elevated fetal insulin levels combined with insulin's mitogenic activity directly stimulating the growth of ...
Willis Kent K Our Lady of the Lake Regional Medical Center, Baton Rouge, LA, USA. Electronic address: - - 2014
The global obesity epidemic is changing the face of maternal-fetal medicine. One in five women is obese at time of conception, and increasing numbers of parturients have undergone bariatric surgery. Recent publication of large, population-based studies and comparison studies of preoperative and post-operative pregnancies have highlighted new risks and benefits ...
Aaronson Jaime J Division of Obstetric Anesthesiology, Department of Anesthesiology, Columbia University, 630 W 168th St, P & S Box 46, New York, NY, - - 2014
The scope of obstetric anesthesia practice ranges far beyond the delivery of care to women for vaginal and cesarean deliveries. Increasingly, obstetric anesthesiologists are involved in the management of anesthetics for new procedures and for new indications. Anesthesia is frequently needed for maternal procedures, as well as fetal procedures, and ...
Zhou F F Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan 610041, - - 2014
Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse pregnancy outcomes. Fetal distress in ICP is an acute process, and the abnormal expression of placental local vasodilatory factors play an essential role. Urocortin (UCN) exhibits a powerful concentration-dependent vasodilatation effect in the utero-placental-fetal unit. Our study ...
Liat Salzer S Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Obesity is a rising global epidemic. Obesity during pregnancy is associated with increased maternal and fetal risks, which is inversely correlated with the severity level of obesity. Other comorbidities are common (diabetes mellitus, hypertensive disorders, etc.) and contribute to an even increased risk. Maternal obesity during pregnancy contributes also to ...
Papachatzi Eleni - - 2014
Abstract Objective: Pre- or early-pregnancy obesity carries significant health implications. This retrospective cohort study investigates the association between pre- or early-pregnancy body mass index (BMI) and the risk of fetal and neonatal death in pregnancies implicated by obesity in a Mediterranean country. Study design: Data on pregnancies delivered during 2003-2008 ...
Gizzo Salvatore - - 2014
Abstract One of the most frequent causes of maternal and perinatal morbidity is represented by hypertensive disorders during pregnancy. Women at high risk must be subjected to a more intensive antenatal surveillance and prophylactic treatments. Many genetic risk factors, clinical features and biomarkers have been proposed but none of these ...
Seidmann L L Institute of Pathology, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany. Electronic address: - - 2014
Idiopathic immaturity is one of the main reasons for latent placental insufficiency and antenatal hypoxia. Postnatal identification of the immature placental phenotype may help early stratification of a heterogeneous population of newborns and individually identify risk of disease in the immediate postnatal life. The aim of the study was to ...
Munnangi S S Department of Pharmaceutical Sciences, St. John's University, Queens, NY, - - 2014
In an effort to improve prenatal screening for Trisomy 21, we evaluated pregnancy associated plasma protein-A2 (PAPP-A2) as a potential novel second trimester biomarker for Trisomy 21. Trisomy 21 and normal control mid-trimester placental samples were subjected to quantitative rt PCR analysis of seven genes we had previously found to ...
Coscia Lisa A LA National Transplantation Pregnancy Registry (NTPR), Gift of Life Institute, 401 N. 3rd Street, Philadelphia, PA 19123, USA. Electronic address: - - 2014
Successful pregnancies have been reported in all types of solid-organ transplant recipients on a variety of immunosuppressive regimens. Immunosuppression is essential to maintain the transplanted organ and maternal health, thus the safety of these medications continues to be studied. This article reviews information in the literature and data from the ...
Junaid T O TO Maternal and Fetal Health Research Centre, Institute of Human Development, Manchester Academic Health Science Centre, St Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, University of Manchester, Manchester M13 9WL, UK. Electronic address: - - 2014
Placental functional impairment in pregnancies with fetal growth restriction (FGR) can arise from fetoplacental vascular abnormalities. We aimed to compare the micro and macrovasculature of placentas from normal pregnancies with those showing late onset FGR. Placental arterial casts (n = 12 normal, 6 FGR) were prepared. Chorionic arterial number and inter-branch length ...
Simják Patrik - - 2014
Abstract Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder of pregnancy. Diagnosis is based on the clinical picture, particularly the presence of pruritus with a deterioration of liver function tests, and typically elevated serum levels of total bile acids. ICP manifests in the second half of pregnancy, ...
Iciek R R Department of Obstetrics and Women's Diseases, Poznan University of Medical Sciences, Poznan, Poland. - - 2014
Type 1 diabetes mellitus (T1DM) is still associated with increased risk of severe maternal and foetal complications but their pathomechanism remains unclear. we investigated the possible role of placental vascular endothelial growth factor (VEGF) and VEGF single nucleotide polymorphisms (SNP) in foetal development in T1DM pregnancies. Sixty seven pregnant women ...
Cetković Aleksandar - - 2014
Pregnancies complicated with antiphospholipd syndrome are associated with the increased perinatal mortality and morbidity. The aim of this study was to assess perinatal outcome in pregnancies with primary antiphospholipd syndrome. This prospective study evaluated perinatal outcome in 25 pregnant women with antiphospholipid syndrome. After establishing vital pregnancy all the patients ...
Aydogan P P Department of Obstetrics and Gynecology, Isparta Maternity Hospital, Isparta, Turkey. - - 2014
The underlying inflammation of endometrium may impede normal implantation of placenta during pregnancy. Our objective is to show cervical colonization of ureaplasma and/or mycoplasma as a marker of endometritis in pregnancies complicated with placenta previa that can be a risk factor for placenta accreta and peripartum hemorrhage. Cervical cultures for ...
Toptas Tayfun - - 2014
No systematic empirical research exists addressing the question of optimal pregnancy termination method in second trimester pregnancies. The purpose of this study was to determine the efficacy and safety of intravaginal misoprostol and extraamniotic Foley catheter combination for second trimester pregnancy termination. A single center observational study was conducted in ...
Gielezynska Agata - - 2014
FMH quantification is necessary to calculate an individual dose of prophylactic anti-RhD immunoglobulin and to diagnose fetal anaemia causes. We encountered a healthy woman with a numerous RBCs containing fetal haemoglobin (HbF). To investigate the cause of this sign and the correct evaluation of fetal RBCs in maternal circulation. Patients ...
Liao Pamela P Department of Obstetrics and Gynaecology, University of Toronto, Toronto - - 2014
To determine if fetal macrosomia in the second trimester predicts the onset of gestational diabetes mellitus (GDM) or large for gestational age (LGA) birth weight. We performed a case-control study using data from the Diabetes in Pregnancy Clinic in our tertiary care hospital. Cases were women with GDM requiring insulin ...
McCloskey Conor C Division of Reproductive Health, Clinical Sciences Research Laboratories, Warwick Medical School University of Warwick, Coventry, - - 2014
Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional labour and post-partum haemorrhage. Uterine contractile patterns are controlled by the generation of complex electrical signals at the myometrial smooth muscle plasma membrane. To identify novel targets to treat conditions associated with uterine dysfunction, ...
Stephens Trina V TV Child & Family Research Institute, BC Children's Hospital, Vancouver, British Columbia, Canada; Department of Pediatrics, University of British Columbia, British Columbia, - - 2014
Adequate dietary protein intake throughout pregnancy is essential to ensure healthy fetal development. Insufficient and excessive maternal dietary protein intakes are both associated with intrauterine growth restriction, resulting in low birth weight infants. The aim of this study was to analyze the dietary protein intake patterns of healthy pregnant women ...
Gebuza Grażyna G Department of Obstetric Care Basics, Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, - - 2014
Birth of a baby has a big impact on women's lives. The presence and help of loved ones favours wellbeing, health, coping with difficult situations. The aim of this study was to determine whether women's satisfaction with life changes during pregnancy and after delivery, and to identify correlates of life satisfaction. Life satisfaction was ...
Fatima P P Professor Parveen Fatima, Professor (Infertility), Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, - - 2014
The hydatidiform mole with coexisting fetus is a rare condition. There have been few reports on this condition following ovulation induction and ART. We describe here the clinical features, management and outcome of a case of complete hydatidiform mole with coexisting viable twin fetus following Intra-cytoplasmic sperm injection. A 29 ...
Zastavna D - - 2014
Karyotyping of 366 couples couples (732 individuals) with early recurrent pregnancy losses in anamnesis revealed chromosomal anomalies in 4.09% (30 cases)--within them 2.05% carry reciprocal translocations, in 0.82%--Robertsonian translocations, 0.55% carry numerical and structural gonosomal anomalies and in 0.27%--marker chromosome of unknown origin. The risk of early reproductive losses in ...
Cressman Alex M AM Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto ON; Faculty of Medicine University of Toronto, Toronto - - 2014
Cocaine abuse during pregnancy is a significant public health problem but is infrequently discussed between physicians and patients. The impact of in utero cocaine exposure on pregnancy and the baby has received significant media attention in preceding decades because of fears of teratogenicity, long-term health consequences, and poor cognitive and ...
Grand'Maison Sophie S Department of Internal Medicine, Centre hospitalier de l'Université de Montréal, Montreal - - 2014
The benefits of ursodeoxycholic acid (UDCA) use for treating intra-hepatic cholestasis of pregnancy (ICP) remain uncertain. A 2010 Cochrane Review of randomized control trials was unable to recommend either for or against the use of UDCA in treating ICP. We conducted a meta-analysis of the literature, including both non-randomized studies ...
Ikechebelu Ji J Department of Obstetrics and Gynecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, - - 2014
The incidence of true knot of the umbilical cord is not only very low but it is often undiagnosed antenatally when present despite the availability of prenatal ultrasonography. When the true knot remains tight, it may impede the circulation of the fetus and may result to fetal death in utero ...
Panda Subrat S Department of Obstetrics & Gynecology, North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences (NEIGRIHMS), Meghalaya, - - 2014
Pregnancies with early onset fetal growth restriction have poor perinatal outcome. Sildenafil citrate (PDE -5 inhibitor) as a vasodilator increases utero-placental blood flow and potentiates fetal growth. In this study, a case was examined and Sildenafil was administered for her. It was found that Sildenafil improved the uterine blood flow ...
Moussa Hind N HN Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, The University of Texas Medical School at Houston, 6431 Fannin, Suite 3.430, Houston, TX 77030, - - 2014
Hypertensive disorders are the most common medical complication of pregnancy, with an incidence of 5-10%, and a common cause of maternal mortality in the USA. Incidence of pre-eclampsia has increased by 25% in the past two decades. In addition to being among the lethal triad, there are likely up to ...
Barati Mojgan M Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, - - 2014
Increased impedance to flow in the uterine arteries assessed by value of the Doppler is associated with adverse pregnancy outcomes, especially pre-eclampsia. We investigated the predictive value of a uterine artery Doppler in the identification of adverse pregnancy outcomes such as 'pre-eclampsia' and 'small fetus for gestational age' (SGA). Three ...
Rajagopalan S S Department of Anesthesiology, Baylor College of Medicine, Houston, TX, USA. Electronic address: - - 2014
Acute aortic dissection in pregnant women is a rare but potentially life-threatening event. Our aim was to evaluate maternal and fetal outcomes of acute aortic dissection during pregnancy. We conducted a review of literature of the PubMed database to identify publications related to pregnant women with acute aortic dissections during ...
Arleo Elizabeth Kagan EK New York-Presbyterian/Weill Cornell, New York, NY, USA. Electronic address: - - 2014
The terms "cornual," "interstitial," and "angular" pregnancies are used inconsistently in the literature. Some sources use "interstitial" and "cornual" synonymously, while others reserve "cornual" for gestations in bicornuate or septate uteri; others distinguish interstitial from angular pregnancy, while in practice, many physicians are unfamiliar with the latter designation. This article ...
Yang Jehn-Hsiahn JH Department of Obstetrics and Gynecology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, - - 2014
To propose a novel method of hysteroscopic resection of complete septate uterus with preservation of duplicated cervix. Retrospective study. Classification: Canadian Task Force classification II-3. Tertiary university hospital. Five women with complete septate uterus and cervical duplication, and who also suffered from infertility with or without pregnancy loss. Bougie-guided or ...
de Jesus Guilherme R GR Department of Obstetrics, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: - - 2014
Pregnancy morbidity is one of the clinical manifestations used for classification criteria of antiphospholipid syndrome (APS). During the 14th International Congress on Antiphospholipid Antibodies (aPL), a Task Force with internationally-known experts was created to carry out a critical appraisal of the literature available regarding the association of aPL with obstetric ...
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