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Results 151 - 200 of 1218
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Horowitz Kari M KM University of Connecticut Health Center, Department of Maternal-Fetal Medicine, Farmington, - - 2014
Abstract Objective: The purpose of this study was to identify risk factors before or during labor to predict primary cesarean delivery for non-reassuring fetal heart tracing in cases of fetal growth restriction undergoing a trial of labor. Study Design: We reviewed charts of all patients with singleton, non-anomalous fetuses found ...
Nadif Raja R Maternal and Fetal Health Research Centre, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, - - 2014
Mice heterozygous for a signalling-deficient leptin receptor (Leprdb/+(db/+)) are widely used as a model of gestational diabetes that results in poor fetal outcomes. This study investigated the importance of fetal genotype (db/+) relative to abnormal maternal metabolism for placental function and therefore fetal growth and offspring health. Wild type (wt) ...
Nelson David B DB 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at - - 2014
Abstract Objective: To examine fetal malformations in mother-infant pairs with and without pregnancy-related hypertension. Methods: This was an observational, population-based study of women delivering a singleton at our hospital. Specific fetal malformations identified in women with gestational hypertension or preeclampsia were compared to those without pregnancy-related hypertension. Women with chronic ...
Ivey Tesa L TL Department of Obstetrics and Gynecology, University of Arkansas for the Medical Sciences, Little Rock, Arkansas, - - 2014
This study was undertaken to determine whether antenatal care can be achieved in women with at-risk pregnancies residing in rural areas with limited access to antenatal care and maternal fetal medicine (MFM) specialists. Over a period of 15 months, 156 women with high-risk pregnancies (diabetes, hypertensive disorders, suspected fetal anomalies, prior ...
Tong Van T VT Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, - - 2014
Evidence of bias of self-reported smoking cessation during pregnancy is reported in high-income countries but not elsewhere. We sought to evaluate self-reported smoking cessation during pregnancy using biochemical verification and to compare characteristics of women with and without biochemically-confirmed cessation in Argentina and Uruguay. In a cross-sectional study from October ...
Hou Lei - - 2014
BackgroundThe association between fetal gender and pregnancy outcomes has been thoroughly demonstrated in western populations. However, this association has not been thoroughly documented in China. The primary objective of the present study is to determine whether the association of adverse pregnancy and labour outcomes with male fetuses applies to the ...
Slopen Natalie N Department of Epidemiology and Biostatistics, University of Maryland College Park, School of Public Health, College Park, United States. Electronic address: - - 2014
Children exposed to social adversity carry a greater risk of poor physical and mental health into adulthood. This increased risk is thought to be due, in part, to inflammatory processes associated with early adversity that contribute to the etiology of many adult illnesses. The current study asks whether aspects of ...
Deveneau Nicolette E NE Department of Obstetrics and Gynecology, Froedtert Medical College Lab Building, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: - - 2014
To determine whether there is a difference in ongoing pregnancy rates (PRs) between patients undergoing IUI with strict sperm morphology ≤4% compared with >4% on initial semen analysis. Retrospective chart review with multivariate analysis. Academic outpatient reproductive center. A total of 408 couples with male and/or female factor infertility and ...
Jackson Sherri S Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, - - 2014
To determine whether there are differences in adverse pregnancy outcomes in very advanced maternal age (vAMA) women who conceived with assisted reproductive technologies (ART) compared with spontaneous conceptions. Retrospective cohort study. Academic tertiary care medical center. A total of 472 women aged ≥45 years who delivered at one institution. Mode of ...
Akaishi R R Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, - - 2014
Autophagy has not been studied extensively in the human placenta. This study was performed to determine whether autophagy is increased in the placentas of women with hypertensive disorders in pregnancy compared to normotensive pregnancies. LC3-II and p62 protein expression were examined by quantitative Western blotting analysis in 40 placentas from ...
Guillaume Anne A CMCO Schiltigheim Department of Gynaecology & Obstetrics, Hôpitaux Universitaires de Strasbourg, 67098 Strasbourg Cedex, - - 2014
Abstract Objective: The aim of this study was to assess the benefit of umbilical cord drainage through cord blood collection (CBC) for the prevention of post-partum haemorrhage (PPH). Methods: This is a retrospective cohort study based on data collected prospectively including all vaginal delivery of singletons pregnancies after 37 weeks ...
Su Emily J EJ Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine and/or Division of Reproductive Science in Medicine, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Context: Fetal growth restriction with abnormal umbilical artery Doppler velocimetry (FGRadv), reflective of elevated fetoplacental vascular resistance, is associated with increased risks of fetal morbidity and mortality even in comparison to growth-restricted fetuses with normal placental blood flow. One major cause of this abnormally elevated fetoplacental vascular resistance is the ...
Dreux Sophie S Biochimie-Hormonologie, CHU Robert Debré, AP-HP, Paris, - - 2014
To analyze the contribution of biochemistry and cytology of fetal ascites fluid to the etiological diagnosis of ascites after ultrasonographic scan, maternal blood sampling and fetal karyotyping. Retrospective study of 100 consecutive cases of non-immune fetal ascites in which ascites fluid was sampled. All women underwent referral ultrasound scan and ...
Pichini Simona S Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanitá, Rome, Italy. Electronic address: - - 2014
Synthetic cathinones have been markedly present in the Spanish drug market in recent years. These substances can be easily obtained in "smart shops", smoke shops, gas stations and web sites where they can be bought and received anonymously avoiding normal law controls. For the first time we present a case ...
Padula Amy M AM Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA. Electronic address: - - 2014
To evaluate associations between traffic-related air pollution during pregnancy and preterm birth in births in four counties in California during years 2000 to 2006. We used logistic regression to examine the association between the highest quartile of ambient air pollutants (carbon monoxide, nitrogen dioxide, particulate matter <10 and 2.5 μm) and ...
Xu Xin-Jie XJ Neuroscience Research Institute, Peking University, Beijing, PR China; Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, PR China; Key Laboratory for Neuroscience, Ministry of Education/National Health and Family Planning Commission, Peking University, Beijing, PR - - 2014
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by persistent impairment in social communication and social interaction. Recent studies revealed that environmental factors, especially the intrauterine developmental environment, played important roles in the development of ASD. It is hypothesized that maternal hyperandrogenism during pregnancy may increase the susceptibility of ...
Weilin Chen C Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing 100730, China. Electronic address: - - 2014
To investigate the efficacy and safety of transabdominal ultrasound-guided suction curettage alone in endogenous cesarean scar pregnancy (CSP). From 2009 to 2013, 21 women with endogenous CSP who had no other therapy underwent suction curettage alone guided with transabdominal ultrasound. All patients were successfully treated with suction curettage alone. No ...
Schwartz Paul J PJ Cincinnati Psychoanalytic Institute, Cincinnati, OH, USA. Electronic address: - - 2014
The season of birth risk factor for schizophrenia exerts a pervasive effect on the global population, particularly at northerly latitudes. The winter infection hypothesis and the low vitamin D hypothesis are both compelling but lack conclusive clinical data. The present work develops a maternal-fetal chronobiological hypothesis for this season of ...
Mazzariol Fernanda S FS Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine. Electronic address: - - 2014
Ultrasound is the primary imaging modality used in the evaluation of first-trimester vaginal bleeding and pelvic pain. This article will summarize the ultrasound findings in normal first-trimester pregnancy, failed pregnancy, ectopic pregnancy, subchorionic hemorrhage, retained products of conception, and gestational trophoblastic disease. Mastery of the spectrum of sonographic findings in ...
Mannion Aisling A Clinical Psychology Unit, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom. Electronic address: - - 2014
This study investigated whether psychotic-like experiences (PLEs) are prevalent amongst women in pregnancy and/or in the early postnatal phase, and whether the predictors identified in the literature for non-puerperal psychosis apply in a general sample of perinatal women. 101 women in their third trimester of pregnancy completed questionnaire measures of ...
Cheek Bradley B Laboratory, Children's Hospital of New Orleans, New Orelans, LA, - - 2014
Eosinophilic T-cell chorionic vasculitis (E/TCV) is composed of eosinophils and T-lymphocytes originating within chorionic vessels, radiating toward the intervillous space and away from the amnion in a fashion different from the fetal vascular response seen in amnionitis. Clinical significance and risk factors are not well established. We report four pregnancies ...
Bakacak Murat M Department of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaraş, - - 2014
Abstract Objective: To investigate the relationship between fetal birth weight and maternal hemoglobin concentrations in different trimesters. Methods: This prospective cross-sectional study comprised 329 women, monitored and delivered between January 2013 and January 2014 in our clinic. Hemoglobin concentrations in all trimesters and all birth weights of the newborns were ...
Bręborowicz Grzegorz H GH Department of Perinatology and Gynecology Poznań University of Medical - - 2014
Abstract Vasa previa is a rare condition in which unsupported by the placenta, umbilical cord blood vessels runs within the placental membranes between internal os of the cervix and presenting part of the fetus. We report an antenatal diagnostic procedure and management of a patient with low-lying placenta and velamentous ...
Edvardsson Kristina - - 2014
Obstetric ultrasound has come to play a significant role in obstetrics since its introduction in clinical care. Today, most pregnant women in the developed world are exposed to obstetric ultrasound examinations, and there is no doubt that the advantages of obstetric ultrasound technique have led to improvements in pregnancy outcomes. ...
Ashley-Martin Jillian - - 2014
Obesity and type-2 diabetes are on the rise and in utero exposure to environmental contaminants is a suspected contributing factor. Our objective was to examine associations between prenatal exposure to potential endocrine disrupting chemicals and markers of fetal metabolic dysfunction. The Maternal-Infant Research on Environmental Chemicals Study (MIREC) recruited 2001 ...
Barry Sinead C SC Department of Obstetrics and Gynecology, Galway University Hospital, National University of Ireland Galway, Newcastle Road, Galway, - - 2014
There are currently limited data describing the natural history and outcome for fetal trisomy 13 diagnosed prenatally. The aim of this study was to evaluate the fetal and neonatal outcome for pregnancies with an established prenatal diagnosis of fetal trisomy 13, and a parental decision for continuation of the pregnancy. ...
Gross Noa N Reproductive Endocrinology and Genetics Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel; Ultrasound Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel; The Hebrew University School of Medicine, Jerusalem, - - 2014
The aim of this study was to characterize the fetal phenotype of a cohort of individuals with confirmed diagnoses of Prader-Willi syndrome (PWS), a severe multi-system genetic disorder, diagnosed by a specific methylation test. We interviewed mothers of 106 individuals with PWS to obtain information about the pregnancy of their ...
Zhang Lillian Y LY Clinical and Population Perinatal Health Research, Kolling Institute of Medical Research, University Department of Obstetrics and Gynaecology, Royal North Shore Hospital, St Leonards, New South Wales, - - 2014
American evidence suggests women are not well informed about the optimal duration of pregnancy or the earliest time for safe birth. Similar evidence does not exist in Australia. To explore pregnant women's beliefs about the duration of pregnancy and the earliest time for safe birth, and to compare the results ...
Roberts Sarah C M SC Advancing New Standards in Reproductive Health (ANSIRH) Program, University of California, San Francisco, Oakland, - - 2014
There is little information about pregnancy-related changes in alcohol use and factors contributing to changes among women with unwanted pregnancies. This study describes changes in alcohol use from before pregnancy recognition to during pregnancy and identifies important predictors of alcohol use severity among women with unwanted pregnancies. Data are from ...
Rifouna M S MS Department of Obstetrics and Gynecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Center, Rotterdam, 3000 CA, The - - 2014
Are first trimester trophoblast volume (TV) and placental bed vascular volume (PBVV) different in IVF or IVF/ICSI pregnancies in comparison with spontaneously conceived pregnancies? Any possible abnormal placentation in IVF or IVF/ICSI pregnancies in comparison with spontaneously conceived pregnancies is not detected by a difference in PBVV or TV at ...
Coleman Beverly G BG Division of Abdominal Imaging, Radiology Department, Hospital of the University of Pennsylvania, Philadelphia, Pa., - - 2014
Myelomeningocele (MMC) is one of the most devastating, nonlethal congenital anomalies worldwide. The live birth prevalence of MMC changed dramatically in the 1980s with the introduction of maternal serum screening and the widespread use of prenatal ultrasound imaging. The high-resolution ultrasound affordable today with state-of-the-art equipment allows us to make ...
Dudley Jessica S JS School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, NSW, 2006, - - 2014
Attachment of the blastocyst and formation of the placenta during pregnancy is dependent on structural and cellular changes occurring in the uterine epithelium and in particular to the plasma membrane of these uterine cells. Desmosome expression decreases during pregnancy in eutherians and some squamates, presumably allowing for remodeling of the ...
Fan Xiujun - - 2014
There is strong evidence that overproduction of soluble fms-like tyrosine kinase-1 (sFLT1) in the placenta is a major cause of vascular dysfunction in preeclampsia through sFLT1-dependent antagonism of VEGF. However, the cause of placental sFLT1 upregulation is not known. Here we demonstrated that in women with preeclampsia, sFLT1 is upregulated ...
Adamson S Lee - - 2014
Preeclampsia, a life-threatening complication of human pregnancy, has a spectrum of clinical signs and is likely caused by an array of pathological mechanisms. However, elevated levels of soluble fms-like tyrosine kinase-1 (sFLT1) in the placenta and in the maternal circulation has emerged as a common finding in women with preeclampsia ...
Avcı Muhittin Eftal ME Tepecik Training and Research Hospital, Department of Perinatology, Yenişehir, Izmir, - - 2014
Abstract Objective: Obesity is critically important to maternal and fetal health during the perinatal period. We have detected an increasing prevalence of maternal obesity in recent years and investigated its complications during pregnancy. Methods: A total of 931 pregnant females were investigated between March 2012 and March 2013. The patients ...
Gomez-Lopez Nardhy N Department of Obstetrics and Gynecology, Perinatology Research Branch, Wayne State University, Detroit, MI, - - 2014
Is increased leukocyte chemotactic activity (CA) from gestational tissues necessary for term or preterm labor in guinea pigs? Tissue extracts were prepared from pregnant guinea pig decidua-myometrium, cervix, fetal membranes (amniochorion), and placenta during early third trimester (n = 8), term not in labor (TNL, n = 5), and term spontaneous labor (TL, n = 6), ...
Shang H H Departments of Obstetrics and Division of Experimental Obstetrics, Study Group in Perinatal Programming, Charité Campus Virchow, Berlin, Germany Department of Obstetrics and Gynecology, Hangzhou First People's Hospital, Hangzhou, - - 2014
The effects of endogenous cortisol on binucleate cells (BNCs), which promote fetal growth, may be mediated by glucocorticoid receptors (GRs), and exposure to dexamethasone (DEX) in early pregnancy stages of placental development might modify this response. In this article, we have investigated the expression of GR as a determinant of ...
Goldacre A D AD Nuffield Department of Population Health, University of Oxford, Oxford, - - 2014
Historically, many women with intellectual disability (ID) did not have children. However, a few decades ago it became more common for women with ID to give birth. Our aim was to compare the completed pregnancies of mothers with ID with other completed pregnancies in a large, defined population. We used ...
Namazy Jennifer J Scripps Clinic, La Jolla, Calif. Electronic address: - - 2014
For many asthma medications, pregnancy safety data remains insufficient. The omalizumab pregnancy registry, EXPECT, evaluates maternal, pregnancy, and infant outcomes after exposure to omalizumab, including incidence of congenital anomalies. EXPECT is a prospective, observational study of pregnant women exposed to ≥1 dose of omalizumab within 8 weeks prior to conception ...
Zheng Wei W Department of Health Sciences, Interdisciplinary Graduate School of Medicine and Engineering, University of - - 2014
Background: Smoking during pregnancy is related to fetal constraint and accelerated postnatal growth. However, the pathways between these factors have not been clarified. Pathway analyses that link these factors can help us better understand the mechanisms involved in this association. Therefore, this study aimed to examine pathways between maternal smoking ...
Fang Shih-Wen SW Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Chiayi, Taiwan, - - 2014
Objective: To evaluate the ability of second-trimester placental volume and vascular indices to predict small-for-gestational-age (SGA) birth weight pregnancies. Material and Methods: Women with singleton pregnancies were prospectively evaluated at 17-20 weeks of gestation. Second-trimester placental volume and vascular indices were obtained and calculated using volume organ computer-aided analysis and ...
Khalil Asma A AA Fetal Medicine Unit, St. George's Hospital, St. George's University of London, London, United Kingdom. Electronic address: - - 2014
We sought to evaluate the association between fetal cerebroplacental ratio (CPR) and intrapartum fetal compromise and admission to the neonatal unit (NNU) in term pregnancies. This was a retrospective cohort study in a single tertiary referral center over a 14-year period from 2000 through 2013. The umbilical artery pulsatility index, ...
Aiken Abigail R AR Office of Population Research, Princeton University, Princeton, - - 2014
We sought to determine the factors associated with selection of rotational instrumental vs cesarean delivery to manage persistent fetal malposition, and to assess differences in adverse neonatal and maternal outcomes following delivery by rotational instruments vs cesarean delivery. We conducted a retrospective cohort study over a 5-year period in a ...
Rac Martha W F MW Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: - - 2014
We sought to apply a standardized evaluation of ultrasound parameters for the prediction of placental invasion in a high-risk population. This was a retrospective review of gravidas with ≥1 prior cesarean delivery who received an ultrasound diagnosis of placenta previa or low-lying placenta in the third trimester at our institution ...
Zhu Jinliang J Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, No. 49 North Huayuan Road, 100191, Haidian District, Beijing, - - 2014
Embryo quality is associated with successful implantation and live births. Our retrospective study was carried out to determine whether or not cleavage stage embryo quality affects the miscarriage rate, pregnancy complications and neonatal outcomes of singletons conceived with assisted reproduction technology. The current study included 11,721 In Vitro Fertilization-Embryo Transfer ...
Hernandez-Andrade E E Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University / Hutzel Women's Hospital, Detroit, Michigan,USA - - - 2014
Early dating of pregnancy by ultrasound measurements is necessary to establish the adequate fetal growth. Customized or individualized estimation of fetal growth is probably a better option than population based curves to identify fetuses at a higher risk of perinatal complications. Biological maternal markers and placental evaluation might contribute in ...
Girsen A I AI Department of Obstetrics and Gynecology, Lucile Packard Children's Hospital at Stanford University, Stanford, CA, - - 2014
Objective:The aim of this study was to investigate the effect of maternal magnesium sulfate (MgSO4) exposure for eclampsia prophylaxis on neonatal intensive care unit (NICU) admission rates for term newborns.Study Design:A secondary analysis of the Maternal-Fetal Medicine Unit Network Cesarean Registry, including primary and repeat cesarean deliveries, and failed and ...
Lassance Luciana L Department of Reproductive Biology, Center for Reproductive Health, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH - - 2014
Context: Low concentrations of estradiol and progesterone are hallmarks of adverse pregnancy outcomes as is maternal obesity. During pregnancy, placental cholesterol is the sole source of sex steroids. Cholesterol trafficking is the limiting step in sex steroid biosynthesis and is mainly mediated by the translocator protein (TSPO), present in the ...
Wainstock Tamar T Department of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer- Sheva 84105, - - 2014
Abstract Prenatal maternal stress is associated with pregnancy complications, poor fetal development and poor birth outcomes. Fetal sex has also been shown to affect the course of pregnancy and its outcomes. The aim of this study was to evaluate whether fetal sex modifies the association between continuous exposure to life-threatening ...
Papanna Ramesha R Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Fetal Center at Children's Memorial Hermann Hospital, UT Health- The University of Texas Medical School at Houston, - - 2014
To determine the risk faxtors for spontaneous preterm delivery (sPTD) or preterm premature rupture of membranes <34 weeks gestation after fetoscopic laser surgery for twin-twin transfusion syndrome (TTTS) and to identify the optimal threshold for pre-operative cervical length (CL). Secondary analysis of prospectively collected data from 449 patients from 3 fetal ...
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