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Results 101 - 150 of 1218
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Vesterinen Hanna M HM UCSF Program on Reproductive Health and the - - 2014
Abstract Objective: Glomerular filtration rate (GFR) may influence concentrations of biomarkers of exposure and their etiologic significance in observational studies of associations between environmental contaminants and fetal growth. It is unknown whether the size of a developing fetus affects maternal GFR such that a small fetus leads to reduced plasma ...
Vandenbroucke Tineke T KU Leuven - University of Leuven, Department of Oncology , Herestraat 49, B-3000 Leuven , Belgium +32 16 34 42 52 ; +32 16 34 42 05 ; - - 2014
Introduction: The treatment of cancer during pregnancy is challenging because of the involvement of two individuals and the necessity of a multidisciplinary approach. An important concern is the potential impact of chemotherapy on the developing fetus. Areas covered: The authors review the available literature on neonatal and long-term outcome of ...
Unger Holger W HW Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia; Walter and Eliza Hall Institute (WEHI), Parkville, Australia; Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea; Department of Obstetrics and Gynaecology, University of Papua New Guinea, Port Moresby, Papua New Guinea; Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; Barcelona Centre for International Health Research (CRESIB), Barcelona, - - 2014
We conducted a prospective longitudinal study of fetal size in rural Papua New Guinea (PNG) involving 439 ultrasound-dated singleton pregnancies with no obvious risk factors for growth restriction. Sonographically estimated fetal weights (EFWs; N = 788) and birth weights (N = 376) were included in a second-order polynomial regression model ...
Børdahl Per E PE Department of Obstetrics and Gynecology, Haukeland University Hospitals/University of Bergen, Bergen, - - 2014
Christian Kielland (1871-1941) designed his forceps to facilitate delivery from the mid-pelvis in cases of malrotation: occipito-transverse and occipito-posterior positions of the fetal head. It was also used for high transverse arrest, today a certain indication for cesarean section. From the very beginning there were professional objections to the use ...
Catalano R A RA School of Public Health, University of California Berkeley, Berkeley, California, - - 2014
Human conception cohorts in gestation during stressful times reportedly yield lower ratios of male to female live births than do other conception cohorts. Much literature attributes this phenomenon to spontaneous abortion of less fit male fetuses. Controversy remains, however, as to whether stressful times make males fetuses less fit ("Shifting ...
Nieddu S M SM Department of Veterinary Medicine, University of Sassari, Sassari, - - 2014
In vitro embryo production (IVP) and cryopreservation are associated with a high incidence of pregnancy complications and fetal abnormalities that may be linked with alterations of placental development. The amniotic fluid is partly derived from the transport of water and solutes across the placenta and provides the fetus with amino acids ...
Jensen Morten Søndergaard MS From the aDepartment of Pediatrics, Regional Hospital of Randers; bPerinatal Epidemiology Research Unit, Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark; cSchool of Bioscience, University of Nottingham, United Kingdom; dDanish Center for Neonatal Screening, Department of Clinical Biochemistry and Immunology, Statens Serum Institute, Copenhagen, Denmark; eDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden; fDepartment of Occupational and Environmental Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark; gReproductive Endocrinology, Leibniz Institute for Farm Animal Biology, Dummerstorf, Germany; and hDanish Ramazzini Center, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, - - 2014
Prenatal exposure to phthalates may pose a threat to human male reproduction. However, additional knowledge about the in vivo effect in humans is needed, and reported associations with genital abnormalities are inconclusive. We aimed to study prenatal di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) exposure in relation to cryptorchidism, hypospadias, ...
Savas Nurten N Nurten Savas, Department of Gastroenterology, Baskent Universitesi Hastanesi, 06990 Istanbul, - - 2014
Gastrointestinal endoscopy has a major diagnostic and therapeutic role in most gastrointestinal disorders; however, limited information is available about clinical efficacy and safety in pregnant patients. The major risks of endoscopy during pregnancy include potential harm to the fetus because of hypoxia, premature labor, trauma and teratogenesis. In some cases, ...
Avent Neil D ND Plymouth University Peninsula Schools of Medicine and Dentistry, Portland Square Building, Drake Circus, Plymouth, PL4 8AA, - - 2014
Incompatibility of red cell and platelet antigens can lead to maternal alloimmunization causing hemolytic disease of the fetus & newborn and fetal neonatal alloimmune thrombocytopenia respectively. As the molecular background of these polymorphisms emerged, prenatal testing using initially fetal DNA obtained from invasively obtained amniotic fluid or chorionic villus was ...
van Klink Jeanine M M JM Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The - - 2014
To evaluate the incidence, type and severity of cerebral injury in the surviving monochorionic co-twin after single fetal demise. We included all monochorionic pregnancies with single fetal demise evaluated at our center between 2002 and 2013. We recorded perinatal characteristics, neonatal outcome and presence of cerebral injury on neuroimaging in ...
Lee Chae Kwan CK Institute of Environmental and Occupational Medicine & Department of Occupational and Environmental Medicine, College of Medicine, Inje University, Busan 614-735, Republic of Korea. Electronic address: - - 2014
Perfluorooctane sulfuric acid (PFOS) is a persistent organic pollutant, causes fetal growth retardation but the mechanism is still unclear. This study focused on PFOS-induced toxicity such as placental trophoblast cell histopathological changes, endocrine function (i.e., prolactin (PRL)-family hormone production) and subsequent fetal growth retardation in mice. Maternal body weight gain, ...
Payne Janet M - - 2014
BackgroundMidwives are an influential profession and a key group in informing women about alcohol consumption in pregnancy and its consequences. There are no current quantitative Australian data on midwives¿ knowledge, attitudes and practice in relation to alcohol consumption during pregnancy and Fetal Alcohol Spectrum Disorder. We aimed to reduce this ...
Lo Jamie O JO Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, - - 2014
Abstract Objective: We examined the morbidities from delivery at earlier gestational ages versus intrauterine fetal demise (IUFD) for women with intrahepatic cholestasis of pregnancy (ICP) to determine the optimal gestational age for delivery. Methods: A decision-analytic model was created to compare delivery at 35 through 38 weeks gestation for different ...
Furnica R M RM Department of Endocrinology, Université catholique de Louvain, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10, 1200, Brussels, - - 2014
Isolated hypothyroxinemia (IH) is defined as a thyroxine level in the lower 5th (severe IH) or 10th percentile (mild IH) of the pregnancy-related reference range and a normal TSH. The etiology of IH remains unknown. This review aims to evaluate the biochemical criteria used to define IH in different published ...
Vrecenak Jesse D JD Center for Fetal Diagnosis and Treatment, The Children's Hospital of Philadelphia, Philadelphia Pa., - - 2014
Background: The outcomes of prenatally diagnosed lung lesions in the context of multigestational pregnancies are unknown. Methods: Of 960 fetal lung lesion cases evaluated at a single tertiary center over 16 years, 30 occurred in multigestational pregnancies. We reviewed this series to aid in prenatal counseling of affected families and ...
Salles Gil F GF Department of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, - - 2014
The well-known mid-trimester drop in blood pressure (BP) during normal pregnancy was recently questioned. To describe longitudinal changes in BP during healthy pregnancies and to investigate factors associated with no mid-trimester drop in BP. A prospective cohort with 158 healthy pregnant women was followed up in a public health care ...
de Assunção Renata Almeida RA Department of Obstetrics and Gynecology, Hospital das Clínicas, University of Sao Paulo, Brazil, São Paulo, SP, - - 2014
To examine the correlation between fetal myocardial performance index (MPI) and hemoglobin levels. Prospective study involving singleton pregnancies at risk of fetal anemia due to maternal anti-D alloimmune disease. Right and left ventricle MPI were evaluated by ultrasound up to 72 hours before cordocentesis. Zeta-score values for fetal MPI and hemoglobin ...
Simoncic Milanka M Department of Pediatric Surgery and Intensive Care, University Medical Centre Ljubljana, Ljubljana, - - 2014
Mediastinal fetal teratoma can be detected as a mass in the chest during a routine prenatal ultra-sound screening. Because of the pressure on mediastinal structures it can be the cause of non-immune hydrops fetalis and polyhydramnion. The development of hydrops fetalis leads to fetal death or premature delivery in most ...
Milligan Natasha N Maternal-Fetal Medicine Division (Placenta Clinic), Department of Obstetrics & Gynaecology, Mount Sinai Hospital, University of Toronto, Ontario, - - 2014
Abstract Objectives: To determine the most reproducible method for the sonographic measurement of placental length. Methods: A prospective study of women with singleton pregnancies who underwent sonographic measurement of placental dimensions during mid-gestation. Two sonographers independently determined placental length using 3 different approaches (linear, curve-linear and panoramic) and placental thickness. ...
O'Tierney-Ginn Perrie P Center for Reproductive Health, MetroHealth Medical Center, Cleveland, - - 2014
Context: The sensitivity of the placenta to maternal insulin remains controversial. Early pregnancy may be a time of increased placental sensitivity to maternal insulin as insulin receptors are abundant on the syncytiotrophoblast in the first trimester, but are far fewer at term. Hypothesis: Maternal insulin secretory response in early, but ...
Mochimaru Aya A Perinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, - - 2014
The aim of this study was to elucidate the risk of poor pregnancy outcomes in women with adenomyosis by comparing their outcomes to those of women without uterine abnormalities. The subjects were 36 women diagnosed with adenomyosis before pregnancy who were managed at a tertiary care center between January 2002 ...
Ooi Poh Vei PV University Maternity Hospital, Limerick, Republic of - - 2014
Abstract Objective: This study sought to determine whether ultrasound assessment of fetal head circumference (FHC) at the onset of labor can predict the likelihood of operative delivery. Methods: We performed a prospective cohort study of 200 nulliparous women with singleton, cephalic, term pregnancies in an Irish Maternity Hospital. Transabdominal ultrasound ...
Mastrolia Salvatore Andrea SA Department of Obstetrics and Gynecology, Azienda Ospedaliero-Universitaria Policlinico di Bari, School of Medicine, University of Bari "Aldo Moro", Bari, - - 2014
Abstract Fetal goiter is an extremely rare complication of pregnancy, its incidence is 1 in 40 000 deliveries. Antithyroid maternal therapy is responsible for 10-15% of fetal congenital hypothyroidism, and can be considered as the most frequent underlying cause for this condition. The frequency of fetal goiter that is associated ...
Sengpiel Verena - - 2014
BackgroundHealth authorities in numerous countries recommend periconceptional folic acid supplementation to prevent neural tube defects. The objective of this study was to examine the association of dietary folate intake and folic acid supplementation during different periods of pregnancy with the risk of spontaneous preterm delivery (PTD).MethodsThe Norwegian Mother and Child ...
Kosinski Przemyslaw P 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, - - 2014
Normal trophoblast growth is one of the more important stages of early pregnancy that has a deciding factor on its later development and normal outcome. Identifying pregnant women who have a high risk of complications connected to hypertension during pregnancy is currently one of the most important tasks of perinatal ...
Parlier Anna Beth AB From the Center for Research, Division of Family Medicine, and the Department of Obstetrics and Gynecology, Mountain Area Health Education Center, Asheville, North - - 2014
To describe how effectively we provided adequate prenatal care and postpartum contraception to prevent repeat, unintended pregnancies to women using opiates or medication maintenance therapy (MMT) during pregnancy. We conducted a retrospective chart review of 94 women using opiates or MMT during 96 pregnancies while receiving prenatal care in the ...
Lildballe Dorte Launholt DL Klinisk Genetisk Afdeling, Aarhus Universitetshospital, Brendstrupgårdsvej 21 C, 8200 Aarhus N, Denmark. - - 2014
We aimed to determine the diagnostic efficiency of quantitative fluorescence polymerase chain reaction (QF-PCR) in a clinical setting where most of the analyses are performed on chorion villus samples from high-risk pregnancies as determined by combined first-trimester screening. A retrospective study on QF-PCR data from all pregnancies in the Central ...
Kus Martin S MS Medical Department, Submarine Squadron SIX, 9168 Second Street, Suite 202, Norfolk, VA - - 2014
The identification of ectopic pregnancy is the primary concern for pregnant patients with an indeterminate ultrasound (an empty uterus or gestational sac). The absence of free fluid and adnexal masses by ultrasound combined with the absence of ectopic risk factors are used to place women in a "low-risk" category. We ...
Conturso Roberto R Department of Obstetrics and Gynecology, Valduce Hospital, Como, - - 2014
Objective: To assess the sonographic visualization of the pericallosal arteries in normal fetuses at 11-13 weeks of gestation using 3D ultrasound. Methods: We prospectively enrolled women with a singleton pregnancy undergoing ultrasound at 11-13 weeks of gestation. A 3D volume with high-definition power Doppler was acquired starting from the sagittal ...
Tongsong Theera T Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, - - 2014
To estimate the association of cordocentesis with small for gestational age, preterm birth, and low birth weight. A cohort study from a tertiary care center. Pregnant women without medical or obstetric complications and without ultrasonographically evident fetal anomalies scheduled for cordocentesis between 16 and 22 weeks of gestation (predominantly to ...
Lynch Courtney D CD Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine; and the College of Public Health, Division of Epidemiology, The Ohio State University, Columbus, - - 2014
To assess whether prepregnancy body mass index (BMI) is independently associated with the timing of pregnancy recognition and initiation of prenatal care. Data from 2009 to 2010 were obtained from the Centers for Disease Control and Prevention's Pregnancy Risk Assessment Monitoring System. The 30 participating states contacted sampled mothers 2-4 ...
Clark Steven L SL Hospital Corporation of America, Nashville, - - 2014
To examine the gestational age at and day and time of delivery in current U.S. obstetric practice. We examined electronic records from 72 hospitals in 16 states during a 4-month period during 2013. Day of week of delivery, time of day of delivery, and route of delivery were examined in ...
Tuovinen Soile S Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland. Electronic address: - - 2014
Hypertensive pregnancy disorders may affect the fetal developmental milieu and thus hint at mechanisms that link prenatal conditions with later developmental outcomes of the offspring. Here, we systematically review studies that have tested whether maternal pre-eclampsia, gestational hypertension, and hypertensive pregnancy disorders as a single diagnostic entity are associated with ...
Love Rozalyn R Department of Obstetrics and Gynecology, Naval Medical Center, Portsmouth, - - 2014
Introduction Encephalomalacia in a developing fetus is a rare and devastating neurological finding on radiologic imaging. Maternal diabetic ketoacidosis (DKA) can lead to metabolic and vascular derangements which can cause fetal encephalomalacia. Case We report the case of a 27-year-old pregnant woman with White's Class C diabetes mellitus who presented in the ...
Francois Lissa L Department of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, New Brunswick, New - - 2014
Introduction Prenatal counseling with regards to the prognosis of a cerebellar abnormality is hindered not only by the diverse clinical presentations but also by the presence of subtle findings. We present a case of a distinct combination of asymmetric cerebellar hypoplasia secondary to an anterior meningoencephalocele through a clival defect that ...
Ritner Julie A JA Department of Ultrasound, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: - - 2014
Prenatal sonography is routinely used to evaluate fetal biometry and anatomy between 16 and 20 weeks. Ventriculomegaly is easily seen on these routine views and is commonly associated with numerous intracranial anomalies. Although ventriculomegaly can be isolated, it should always prompt a detailed search to evaluate for an underlying cause. Using ...
Doubilet Peter M PM Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02116, USA. Electronic address: - - 2014
Ultrasound is a valuable diagnostic test throughout the first trimester of pregnancy. Early in this trimester, it is used to distinguish between normal intrauterine, failed intrauterine, and ectopic pregnancies. Later it can be used with maternal blood tests to screen for trisomy 21 and other forms of aneuploidy, and in ...
Cantu Jessica J Departments of Obstetrics and Gynecology, the University of Alabama at Birmingham, Birmingham, Alabama; the University of Pittsburgh, Pittsburgh, Pennsylvania; the University of Texas Southwestern Medical Center, Dallas, Texas; the University of Cincinnati, Cincinnati, Ohio; the University of Utah, Salt Lake City, Utah; Columbia University, New York, New York; the University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Case Western Reserve University-MetroHealth Medical Center, Cleveland, Ohio; Northwestern University, Chicago, Illinois; the University of Texas Health Science Center at Houston-Children's Memorial Hermann Hospital, Houston, Texas; The Ohio State University, Columbus, Ohio; Drexel University, Philadelphia, Pennsylvania; the University of Texas Medical Branch, Galveston, Texas; Wayne State University, Detroit, Michigan; the George Washington University Biostatistics Center, Washington, DC; and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, - - 2014
To estimate the frequency of abnormal laboratory test results in pregnancy-associated hypertension and the relationship with pregnancy outcomes. This was a secondary analysis of a multicenter trial of vitamin C and E for prevention of pregnancy-associated hypertension in low-risk nulliparous women. Laboratory abnormalities included: platelets less than 100,000/mm, aspartate aminotransferase ...
Kyvernitakis I I Department of Gynecology and Obstetrics, Philipps-University of Marburg, Marburg , in cooperation with the Clara Angela Foundation, - - 2014
Objective: Patients with a history of one or more conizations have an increased risk of spontaneous preterm birth (SPTB). The aim of this study was to investigate the outcome of pregnancies in patients with a history of conization and early treatment with a cervical pessary. Methods: In this pilot observational ...
Dutman Annemiek Christien AC a University Medical Center Utrecht, - - 2014
Abstract Cases of unexplained intrauterine fetal death (IUFD) can be reduced by full placental examination, with or without autopsy. Determination of the umbilical coiling index (UCI) is considered to be a part of full placental examination. Umbilical hypercoiling (UCI above 0,30 coils/ cm) is associated with IUFD. In a large ...
Figueras Francesc F Fetal and Perinatal Research Centre, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Maternal-Fetal Medicine Department, Hospital Clínic, University of Barcelona, Spain; University of Barcelona, - - 2014
The objective of this study was to develop an integrated model with the best performing criteria to predict adverse outcome in small-for-gestational age (SGA) pregnancies. Cohort of 509 pregnancies with suspected SGA fetus eligible for trial of labor was recruited prospectively, and data on the perinatal outcome recorded. A predictive ...
Romero Stephanie T ST University of Utah School of Medicine, Department of Obstetrics and Gynecology; Intermountain Medical Center, Division of Maternal Fetal - - 2014
Our objective was to characterize the proportion and type of genetic abnormalities in early pregnancy losses at different developmental stages; we hypothesize that these rates will differ. Women with pregnancy loss < 20 weeks gestation (n = 86) were enrolled at the time of diagnosis. Maternal tissue without a fetal component was found in 13 ...
Hromadnikova Ilona I Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, Ruska 87, 100 00, Prague, Czech Republic, - - 2014
The study describes the stress response in the central cotyledon zone of placental tissue and in maternal whole peripheral blood to pregnancy related complications including gestational hypertension (n = 31), preeclampsia w or w/o fetal growth restriction (n = 95), and fetal growth restriction (n = 39) using real-time RT-PCR and genes encoding Hsp27, Hsp60, Hsp70, ...
Karakus Ruhat R Department of Perinatology, Zekai Tahir Burak Women's Health Care, Training and Research Hospital, Ankara, - - 2014
We aimed to evaluate the association of fetal aortic isthmus (AoI) Doppler flow measurements in intrauterine growth-restricted (IUGR) fetuses with fetal outcome. The data presented in this prospective cohort study were obtained from 74 IUGR and 71 appropriate-for-gestational-age (AGA) fetuses of singleton pregnancies with normal medical and obstetric histories that ...
Valente Christine C University of Bristol, UK. Electronic address: - - 2014
A sizeable economics literature explores the effect of prenatal shocks on later health or socioeconomic status. Work in other disciplines, following the seminal contribution of Trivers and Willard (1973), suggests that prenatal shocks may increase fetal loss and reduce the number of boys relative to girls at birth. This has ...
Guang Yang Y Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, - - 2014
The aim of the study described here was to examine the potential of tomography ultrasonography imaging (TUI) in evaluation of the fetal anal sphincter. In this prospective cross-sectional study of the fetal anal sphincter with TUI, 326 singleton pregnancies (mean age = 28 y, range: 22-38 y) were scanned at 19-40 wk of gestation. The ...
Ge Qinyu Q Key Laboratory for Child Development and Learning Science, Ministry of Education, Research Center for Learning Science, Southeast University, Nanjing 2100096, P.R. - - 2015
Macrosomia is associated with problems at birth and has life-long health implications for the infant. The aim of this study was to profile the plasma microRNAs (miRNAs or miRs) and evaluate the potential of circulating miRNAs to predict fetal macrosomia. The expression levels of miRNAs in plasma samples obtained from pregnant ...
Trønnes Håvard H Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Bergen, - - 2014
Maternal asthma has been associated with adverse pregnancy outcomes. Little is known about the influence of other atopic diseases on pregnancy outcomes. We assessed how various maternal atopic diseases might affect preterm birth, stillbirth, and neonatal death. By linking Norwegian national registries, we acquired information on maternal health, socio-demographic factors, ...
Yang Zhang Z Department of Obstetrics and Gynecology, Peking University People's - - 2014
Abstract Objective: To investigate the clinical characteristics, management, maternal and fetal outcomes in pregnant patients with myelodysplastic syndrome (MDS). Method: A retrospective analysis was conducted on 25 pregnant women with MDS between June 1998 and January 2013. The clinical data were summarized. These patients were divided into poor outcome group ...
Freud A A Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, - - 2014
Abstract Objective: To determine the reproductive outcome following hysteroscopic septum resection in women with a septated uterus and a history of spontaneous miscarriages or premature deliveries. Study Design: A retrospective, cohort study investigating reproductive outcomes following septum resection was conducted. Patients who had no other apparent cause for spontaneous miscarriage ...
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