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Gomez-Lopez Nardhy N Department of Obstetrics and Gynecology, Perinatology Research Branch, Wayne State University, Detroit, MI, - - 2014
Is increased leukocyte chemotactic activity (CA) from gestational tissues necessary for term or preterm labor in guinea pigs? Tissue extracts were prepared from pregnant guinea pig decidua-myometrium, cervix, fetal membranes (amniochorion), and placenta during early third trimester (n = 8), term not in labor (TNL, n = 5), and term spontaneous labor (TL, n = 6), ...
Shang H H Departments of Obstetrics and Division of Experimental Obstetrics, Study Group in Perinatal Programming, Charité Campus Virchow, Berlin, Germany Department of Obstetrics and Gynecology, Hangzhou First People's Hospital, Hangzhou, - - 2014
The effects of endogenous cortisol on binucleate cells (BNCs), which promote fetal growth, may be mediated by glucocorticoid receptors (GRs), and exposure to dexamethasone (DEX) in early pregnancy stages of placental development might modify this response. In this article, we have investigated the expression of GR as a determinant of ...
Goldacre A D AD Nuffield Department of Population Health, University of Oxford, Oxford, - - 2014
Historically, many women with intellectual disability (ID) did not have children. However, a few decades ago it became more common for women with ID to give birth. Our aim was to compare the completed pregnancies of mothers with ID with other completed pregnancies in a large, defined population. We used ...
Zhu Jinliang J Reproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, No. 49 North Huayuan Road, 100191, Haidian District, Beijing, - - 2014
Embryo quality is associated with successful implantation and live births. Our retrospective study was carried out to determine whether or not cleavage stage embryo quality affects the miscarriage rate, pregnancy complications and neonatal outcomes of singletons conceived with assisted reproduction technology. The current study included 11,721 In Vitro Fertilization-Embryo Transfer ...
Zheng Wei W Department of Health Sciences, Interdisciplinary Graduate School of Medicine and Engineering, University of - - 2014
Background: Smoking during pregnancy is related to fetal constraint and accelerated postnatal growth. However, the pathways between these factors have not been clarified. Pathway analyses that link these factors can help us better understand the mechanisms involved in this association. Therefore, this study aimed to examine pathways between maternal smoking ...
Fang Shih-Wen SW Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Chiayi, Taiwan, - - 2014
Objective: To evaluate the ability of second-trimester placental volume and vascular indices to predict small-for-gestational-age (SGA) birth weight pregnancies. Material and Methods: Women with singleton pregnancies were prospectively evaluated at 17-20 weeks of gestation. Second-trimester placental volume and vascular indices were obtained and calculated using volume organ computer-aided analysis and ...
Hernandez-Andrade E E Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University / Hutzel Women's Hospital, Detroit, Michigan,USA - - - 2014
Early dating of pregnancy by ultrasound measurements is necessary to establish the adequate fetal growth. Customized or individualized estimation of fetal growth is probably a better option than population based curves to identify fetuses at a higher risk of perinatal complications. Biological maternal markers and placental evaluation might contribute in ...
Girsen A I AI Department of Obstetrics and Gynecology, Lucile Packard Children's Hospital at Stanford University, Stanford, CA, - - 2014
Objective:The aim of this study was to investigate the effect of maternal magnesium sulfate (MgSO4) exposure for eclampsia prophylaxis on neonatal intensive care unit (NICU) admission rates for term newborns.Study Design:A secondary analysis of the Maternal-Fetal Medicine Unit Network Cesarean Registry, including primary and repeat cesarean deliveries, and failed and ...
Lassance Luciana L Department of Reproductive Biology, Center for Reproductive Health, MetroHealth Medical Center, 2500 MetroHealth Dr, Cleveland, OH - - 2014
Context: Low concentrations of estradiol and progesterone are hallmarks of adverse pregnancy outcomes as is maternal obesity. During pregnancy, placental cholesterol is the sole source of sex steroids. Cholesterol trafficking is the limiting step in sex steroid biosynthesis and is mainly mediated by the translocator protein (TSPO), present in the ...
Wainstock Tamar T Department of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer- Sheva 84105, - - 2014
Abstract Prenatal maternal stress is associated with pregnancy complications, poor fetal development and poor birth outcomes. Fetal sex has also been shown to affect the course of pregnancy and its outcomes. The aim of this study was to evaluate whether fetal sex modifies the association between continuous exposure to life-threatening ...
Papanna Ramesha R Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Fetal Center at Children's Memorial Hermann Hospital, UT Health- The University of Texas Medical School at Houston, - - 2014
To determine the risk faxtors for spontaneous preterm delivery (sPTD) or preterm premature rupture of membranes <34 weeks gestation after fetoscopic laser surgery for twin-twin transfusion syndrome (TTTS) and to identify the optimal threshold for pre-operative cervical length (CL). Secondary analysis of prospectively collected data from 449 patients from 3 fetal ...
Wade Mark M a Department of Applied Psychology and Human Development , University of Toronto , Toronto , ON , - - 2014
Despite documented effects on fetal brain development, little is currently known about the relationship between maternal pregnancy hypertension and child neuropsychological outcomes. This brief report examined the association between maternal hypertension during pregnancy and children's social cognition and executive functioning when children were 18 months, 3 years, and 4.5 years. A community sample ...
Jeremic Katarina - - 2014
Abstract Aims: The study aim was to evaluate pregnancy outcomes in patients with antiphospholipid syndrome (APS) and to determine which clinical parameters present risk factors for adverse pregnancy outcomes in these patients. Methods: The study included 55 patients with APS treated at the Clinic for Ob/Gyn, Clinical Center of Serbia, ...
Ghi T T Department of Obstetrics and Gynecology, St. Orsola Malpighi University Hospital, Bologna, - - 2014
Abstract Objective: to compare the accuracy of transperineal (TP) ultrasound with transabdominal (TA) approach in the sonographic assessment of fetal occiput position during the second stage of labour. Methods: A series of low-risk women at term attending the labour ward of three university hospitals were prospectively recruited for the purpose ...
He Ping P Department of Obstetrics and Gynecology, Guangzhou Women & Children Medical Center, Guangzhou Medical University , Guangzhou, Guangdong , People's Republic of China - - 2014
Abstract The aim of the present study was to report a 3-year experience on the prenatal control of Hb Bart's (γ4) disease in Mainland China. All pregnancies with fetal Hb Bart's disease were included from January 2011 to December 2013. The main clinical characteristics of the affected pregnancies were reviewed, ...
Gohir Wajiha W Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton - - 2014
Chronic disease risk is inextricably linked to our early life environment where maternal, fetal and childhood factors predict disease risk later in life. Currently, maternal obesity is a key predictor of childhood obesity and metabolic complications in adulthood. Although the mechanisms are unclear, new and emerging evidence points to our ...
Alecsandru D D Department of Immunology and Department of Reproductive Endocrinology and Infertility, Instituto Valenciano de Infertilidad-Madrid, Rey Juan Carlos University (IVI), Madrid, Spain - - 2014
In patients with recurrent miscarriages (RM) or recurrent implantation failure (RIF), does the maternal killer immunoglobulin-like receptor (KIR) haplotype have an impact on live birth rates per cycle after embryo transfer with the patient's own or donated oocytes? After double embryo transfer (DET) in patients with the maternal KIR AA ...
Eindhoven S C SC Division of Obstetrics and Prenatal Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre, Rotterdam, The - - 2014
Is in vitro fertilization treatment with or without intracytoplasmatic sperm injection (IVF/ICSI) associated with changes in first and second trimester embryonic and fetal growth trajectories and birthweight in singleton pregnancies? Embryonic and fetal growth trajectories and birthweight are not significantly different between pregnancies conceived with IVF/ICSI treatment and spontaneously conceived ...
Li Weifeng - - 2014
The incidence of bilateral tubal pregnancy is rising due to the increase of pelvic inflammatory disease and assisted reproductive techniques. Because the clinical manifestations of bilateral tubal pregnancy are not specific, we often ignore inspection of the other fallopian tube when focusing on the lesions, which may cause misdiagnosis. A ...
Schierding William - - 2014
Recent evidence suggests that prolonged pregnancies beyond 42 weeks of gestation (post-term births) are associated with long-term adverse health outcomes in the offspring. There is evidence that post-term birth has not only environmental causes, but also significant heritability, suggesting genetic and/or epigenetic influences interact with environmental cues to affect gestational ...
Ben-Chetrit Eli E Infectious Disease Unit, Shaare Zedek Medical Center, Jerusalem, - - 2014
Travel-related acquisition of schistosomiasis in Africa is well established. Data concerning Schistosoma infection in pregnant travelers are lacking and treatment derives from studies in endemic regions. This study was a retrospective case-series of pregnant patients who were infected with Schistosoma species. Data regarding exposure history, clinical presentation, diagnosis, treatment, and ...
Romano-Keeler Joann J Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, - - 2014
While critical for normal development, the exact timing of establishment of the intestinal microbiome is unknown. For example, although preterm labor and birth have been associated with bacterial colonization of the amniotic cavity and fetal membranes for many years, the prevailing dogma of a sterile intra-uterine environment during normal term ...
Kim Yeon Mee YM Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, - - 2014
Abstract Objective: Acute atherosis is characterized by subendothelial lipid-filled foam cells, fibrinoid necrosis and perivascular lymphocytic infiltration. This lesion is generally confined to non-transformed spiral arteries and is frequently observed in patients with preeclampsia. However, the frequency of acute atherosis in the great obstetrical syndrome is unknown. The purpose of ...
Cleary Kirsten Lawrence KL Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th St, 16-66, New York, NY 10032. Electronic address: - - 2014
Statins (3-hydroxy-3 methyl-glutaryl coenzyme-A reductase inhibitors) are the most commonly prescribed cholesterol-lowering medications due to their efficacy in reducing cardiovascular mortality and morbidities, tolerability, and safety profiles. Based on pathophysiologic similarities between cardiovascular disease and preeclampsia, a common and dangerous complication of pregnancy, there is an increasing interest in studying ...
Patti Simona S Department of Gynecology, Obstetrics and Urology, Sapienza University of Rome, Rome, - - 2014
The autoimmune lymphoproliferative syndrome (ALPS) is a disorder of abnormal lymphocyte survival caused by the dysregulation of the Fas apoptotic pathway. The Fas gene is expressed at the maternal-fetal interface and is involved in the regulation of immune response and implantation. Altered Fas expression may result in altered apoptosis and, ...
Ulubay Mustafa M Department of Obstetrics and Gynecology, Gulhane Military Medical Academy, Ankara, - - 2014
Impetigo herpetiformis (IH) is a very rare type of dermatosis seen in pregnancy. According to the published work, IH during pregnancy is associated with the risk of stillbirth, and obstetric management in such cases is very important. Early recognition is important to reduce both maternal and fetal morbidity. We present ...
Li Yi-Dan YD Department of Ultrasound, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. - - 2014
Fetal cardiac rhabdomyoma is the most common cardiac tumor in fetuses. However, this benign tumor can cause hemodynamic repercussions and intrauterine fetal mortality. The present study reports a case of rare fetal cardiac rhabdomyoma located in the right atrium, accompanied by premature restriction of the foramen ovale and moderate pericardial ...
Mueller N T NT 1] Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA [2] Institute of Human Nutrition and Department of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, - - 2014
Background/Objectives:Cesarean section (CS) and antibiotic use during pregnancy may alter normal maternal-fetal microbiota exchange, thereby contributing to aberrant microbial colonization of the infant gut and increased susceptibility to obesity later in life. We hypothesized that i) maternal use of antibiotics in the second or third trimester of pregnancy and ii) ...
Coleman Alan A Cincinnati Fetal Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA; Division of Pediatric, General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, - - 2014
To evaluate fetal lung growth rate for isolated left-sided CDH using serial MRI-based volumetric measures. Early and late gestational (22-30 and > 30 weeks' gestation) lung volumetry was obtained by fetal MRI in 47 cases of isolated left-sided CDH. At both of these time points, lung volume indices, including total ...
Bevilacqua E E Department of Obstetrics and Gynecology, University Hospital Brugmann, Brussels, - - 2014
To report clinical implementation of cell-free (cf)DNA analysis of maternal blood in screening for trisomies 21, 18 and 13 in twin pregnancies and examine variables that could influence the failure rate of the test. cfDNA testing was performed in 515 twin pregnancies at 10-28 weeks' gestation. Failure rate of the ...
Coccia Maria Elisabetta ME Department of Clinical and Experimental Biomedical Sciences, University of Florence, Florence, Italy - - 2014
To assess the accurate dating of the cessation of pregnancy in patients with recurrent pregnancy loss (RPL) and to evaluate the incidence and recurrence rate of pregnancy losses in similar gestational age. In a retrospective cohort study, couples with history of RPL and availability of precise documentation regarding previous pregnancy ...
Zhou Yan Y Department of Obstetrics and Gynecology, University of California, San Francisco, San Francisco, - - 2014
Successful human pregnancy requires extensive invasion of maternal uterine tissues by the placenta. Invasive extravillous trophoblasts derived from cytotrophoblast progenitors remodel maternal arterioles to promote blood flow to the placenta. In the pregnancy complication preeclampsia, extravillous trophoblasts invasion and vessel remodeling are frequently impaired, likely contributing to fetal underperfusion and ...
Turgal Mert - - 2014
Abstract Objective: Nonimmune hydrops fetalis (NIHF) is one of the most difficult problems related to pregnancy. The aim of this study was to evaluate the etiological analysis as well as the fetal and neonatal outcomes of NIHF. Methods: We reviewed the prenatal sonographic data and postnatal medical records of pregnant ...
Stanescu A D AD "Saint John" Clinical Emergency Hospital, Bucur Maternity, University of Medicine and Pharmacy "Carol Davila", Bucharest, - - 2014
To determine the relationship between idiopathic polyhydramnios and fetal gender in the absence of fetal or maternal abnormalities. This was a retrospective population-based register study. 295 women with singleton pregnancies complicated by idiopathic polyhydramnios (amniotic fluid index (AFI) higher than 24 cm) who were delivered at our institution from January 2002 ...
Li Guang Tai GT Department of Obstetrics and Gynecology, China Meitan General Hospital, No.29 Xibahe Nanli, Chaoyang District, Beijing, 100028, People's Republic of - - 2014
To evaluate the efficacy and safety of a symbol "&" compression suture technique in controlling severe atonic postpartum hemorrhage with placenta previa accreta during cesarean delivery. Nine women with heavy postpartum bleeding from uterine inertia and placenta previa percret, which did not react to conventional initial management protocols, were underwent ...
East Christine E CE School of Nursing and Midwifery/Maternity Services, Monash University/Monash Health, 246 Clayton Road, Clayton, Victoria, Australia, - - 2014
The use of conventional cardiotocographic (CTG) monitoring of fetal well-being during labour is associated with an increased caesarean section rate, compared with intermittent auscultation of the fetal heart rate, resulting in a reduction in neonatal seizures, although no differences in other neonatal outcomes. To improve the sensitivity of this test ...
Malm Mari-Cristin - - 2014
Low maternal awareness of fetal movements is associated with negative birth outcomes. Knowledge regarding pregnant women's compliance with programs of systematic self-assessment of fetal movements is needed. The aim of this study was to investigate women's experiences using two different self-assessment methods for monitoring fetal movements and to determine if ...
Dvela-Levitt Moran M Departments of Medical Neurobiology, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, - - 2014
Ouabain, a steroid present in the circulation and in various tissues, was shown to affect the growth and viability of various cells in culture. To test for the possible influence of this steroid on growth and viability in vivo, we investigated the involvement of maternal circulating ouabain in the regulation ...
McKechnie Anne Chevalier AC University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA - - 2014
Using a cross-sectional, grounded dimensional analysis study design, we collected demographic and health information and conducted telephone interviews with 37 expectant parents of 26 fetuses within 25 families. We describe a theoretical model with a core process of preparing heart and mind for becoming a parent following a diagnosis of ...
Ekin Atalay A Department of Perinatology, Izmir Tepecik Training and Research Hospital, Izmir, - - 2014
Abstract Objective: Our purpose was to determine whether singleton pregnancies complicated by preterm premature rupture of membranes (PPROM) and oligohydramnios are at an increased risk of having maternal and neonatal morbidity. Methods: We performed a retrospective analysis of 389 women with PPROM between 24 and 34 weeks of gestation in ...
Malvasi Antonio A Santa Maria Hospital, Gynecology and Obstetric, Via A. De Ferraris 18-D, Bari, 70124 - - 2014
Abstract Asynclitism is also defined as the "oblique malpresentation of the fetal head in labor". Asynclitism clinical diagnosis, during vaginal examination, may be difficult, it may case failure of labor progress and the use of operative or cesarean delivery. We reviewed all literature about asynclitism, by performing an extensive electronic ...
Bayerl Doris S DS Department of Behavioural and Molecular Neurobiology, University of Regensburg, Regensburg, - - 2014
Maternal behaviour in rodents is mediated by the central oxytocin and vasopressin systems, among others. The role of vasopressin, acting via the V1a receptor (V1aR), on maternal care and maternal aggression has recently been described. However, a potential involvement of the V1b receptor (V1bR) in maternal behaviour has only been ...
Sharp Gemma C GC MRC Centre for Reproductive Health, University of Edinburgh Queen's Medical Research Centre, Edinburgh, UK, EH16 - - 2014
Fetal assessment following preterm prelabour rupture of membranes (PPROM) may result in earlier delivery due to earlier detection of fetal compromise. However, early delivery may not always be in the fetal or maternal interest, and the effectiveness of different fetal assessment methods in improving neonatal and maternal outcomes is uncertain. ...
Pacheco Luis D LD *Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine †Department of Anesthesiology, Division of Surgical Critical Care, The University of Texas Medical Branch at Galveston, Galveston, - - 2014
Myocardial infarction complicating pregnancy is an important cause of maternal morbidity and mortality. The coexistence of obesity, diabetes, chronic hypertension, and delayed age at pregnancy is expected to increase the prevalence of myocardial infarction during pregnancy. Timely treatment in the form of percutaneous coronary intervention has dramatically improved outcomes. Early ...
Shi Xiaolin X Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, - - 2014
Noninvasive prenatal testing (NIPT) by massively parallel sequencing (MPS) of the circulating cell free fetal (cff) DNA during the second trimester of pregnancy is now a frontline test for detecting common fetal chromosomal abnormalities. However, the availability of an earlier test result in the first trimester would enable better clinical ...
Ovaere Céline C Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, - - 2014
Introduction: We review the characteristics and prenatal choices of patients recently evaluated for neural tube defects (NTD) at two tertiary units. The prenatal diagnosis of NTD allows parents to consider all prenatal options. In selected cases of spina bifida aperta this also includes fetal surgery, which we started offering after ...
Shechter-Maor G G Department of OBGYN, Meir Medical Center, Kfar Saba, - - 2014
Objective:Compare mechanical and pharmacological ripening for patients with oligohydramnios at term.Study design:Fifty-two patients with oligohydramnios ⩽5 cm and Bishop score ⩽6 were randomized for labor induction with a vaginal insert containing 10 mg timed-release dinoprostone (PGE2) or double-balloon catheter. The primary outcome was time from induction to active labor. Time to labor, ...
Yamasato Kelly K Department of Obstetrics, Gynecology, and Women's Health, University of Hawaii John A Burns School of Medicine, 1319 Punahou Street, #824, Honolulu, HI, 96826, USA, - - 2014
The purpose of this study was to assess induction rates, maternal, and neonatal outcomes following adoption of a policy prohibiting elective inductions at less than 39 weeks gestation and inductions between 39 and 41 weeks with an unfavorable cervix. A retrospective cohort study of all deliveries greater than or equal to 37 weeks ...
Adler E E Department of Pathology, Montefiore Medical Center, Bronx, NY, USA. Electronic address: - - 2014
Trophoblast inclusions (TIs) are often found in placentas of genetically abnormal gestations. Although best documented in placentas from molar pregnancies and chromosomal aneuploidy, TIs are also associated with more subtle genetic abnormalities, and possibly autism. Less than 3% of non-aneuploid, non-accreta placentas have TIs. We hypothesize that placental genetics may ...
Dahlstrom Jane E JE 1Department of Anatomical Pathology, ACT Pathology, Canberra Hospital 2ANU Medical School, Canberra 3Department of Endocrinology, Canberra Hospital 4Department of Obstetrics and Gynaecology, Calvary Hospital 5John James Medical Centre, Deakin, - - 2014
A 26-year-old Indian lady G2P0 presented at 33 weeks gestation complaining of itch. Liver function tests revealed an elevated alkaline phosphatase (ALKP) of 2983 U/L (normal range 20-110) which on fractionation was a placental or placental-like isoenzyme. All other investigations, including fetal ultrasound, were normal. Labour was induced at 37 weeks ...
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