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McKechnie Anne Chevalier AC University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA - - 2014
Using a cross-sectional, grounded dimensional analysis study design, we collected demographic and health information and conducted telephone interviews with 37 expectant parents of 26 fetuses within 25 families. We describe a theoretical model with a core process of preparing heart and mind for becoming a parent following a diagnosis of ...
Ekin Atalay A Department of Perinatology, Izmir Tepecik Training and Research Hospital, Izmir, - - 2014
Abstract Objective: Our purpose was to determine whether singleton pregnancies complicated by preterm premature rupture of membranes (PPROM) and oligohydramnios are at an increased risk of having maternal and neonatal morbidity. Methods: We performed a retrospective analysis of 389 women with PPROM between 24 and 34 weeks of gestation in ...
Malvasi Antonio A Santa Maria Hospital, Gynecology and Obstetric, Via A. De Ferraris 18-D, Bari, 70124 - - 2014
Abstract Asynclitism is also defined as the "oblique malpresentation of the fetal head in labor". Asynclitism clinical diagnosis, during vaginal examination, may be difficult, it may case failure of labor progress and the use of operative or cesarean delivery. We reviewed all literature about asynclitism, by performing an extensive electronic ...
Bayerl Doris S DS Department of Behavioural and Molecular Neurobiology, University of Regensburg, Regensburg, - - 2014
Maternal behaviour in rodents is mediated by the central oxytocin and vasopressin systems, among others. The role of vasopressin, acting via the V1a receptor (V1aR), on maternal care and maternal aggression has recently been described. However, a potential involvement of the V1b receptor (V1bR) in maternal behaviour has only been ...
Sharp Gemma C GC MRC Centre for Reproductive Health, University of Edinburgh Queen's Medical Research Centre, Edinburgh, UK, EH16 - - 2014
Fetal assessment following preterm prelabour rupture of membranes (PPROM) may result in earlier delivery due to earlier detection of fetal compromise. However, early delivery may not always be in the fetal or maternal interest, and the effectiveness of different fetal assessment methods in improving neonatal and maternal outcomes is uncertain. ...
Pacheco Luis D LD *Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine †Department of Anesthesiology, Division of Surgical Critical Care, The University of Texas Medical Branch at Galveston, Galveston, - - 2014
Myocardial infarction complicating pregnancy is an important cause of maternal morbidity and mortality. The coexistence of obesity, diabetes, chronic hypertension, and delayed age at pregnancy is expected to increase the prevalence of myocardial infarction during pregnancy. Timely treatment in the form of percutaneous coronary intervention has dramatically improved outcomes. Early ...
Shi Xiaolin X Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, - - 2014
Noninvasive prenatal testing (NIPT) by massively parallel sequencing (MPS) of the circulating cell free fetal (cff) DNA during the second trimester of pregnancy is now a frontline test for detecting common fetal chromosomal abnormalities. However, the availability of an earlier test result in the first trimester would enable better clinical ...
Ovaere Céline C Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, - - 2014
Introduction: We review the characteristics and prenatal choices of patients recently evaluated for neural tube defects (NTD) at two tertiary units. The prenatal diagnosis of NTD allows parents to consider all prenatal options. In selected cases of spina bifida aperta this also includes fetal surgery, which we started offering after ...
Shechter-Maor G G Department of OBGYN, Meir Medical Center, Kfar Saba, - - 2014
Objective:Compare mechanical and pharmacological ripening for patients with oligohydramnios at term.Study design:Fifty-two patients with oligohydramnios ⩽5 cm and Bishop score ⩽6 were randomized for labor induction with a vaginal insert containing 10 mg timed-release dinoprostone (PGE2) or double-balloon catheter. The primary outcome was time from induction to active labor. Time to labor, ...
Yamasato Kelly K Department of Obstetrics, Gynecology, and Women's Health, University of Hawaii John A Burns School of Medicine, 1319 Punahou Street, #824, Honolulu, HI, 96826, USA, - - 2014
The purpose of this study was to assess induction rates, maternal, and neonatal outcomes following adoption of a policy prohibiting elective inductions at less than 39 weeks gestation and inductions between 39 and 41 weeks with an unfavorable cervix. A retrospective cohort study of all deliveries greater than or equal to 37 weeks ...
Adler E E Department of Pathology, Montefiore Medical Center, Bronx, NY, USA. Electronic address: - - 2014
Trophoblast inclusions (TIs) are often found in placentas of genetically abnormal gestations. Although best documented in placentas from molar pregnancies and chromosomal aneuploidy, TIs are also associated with more subtle genetic abnormalities, and possibly autism. Less than 3% of non-aneuploid, non-accreta placentas have TIs. We hypothesize that placental genetics may ...
Dahlstrom Jane E JE 1Department of Anatomical Pathology, ACT Pathology, Canberra Hospital 2ANU Medical School, Canberra 3Department of Endocrinology, Canberra Hospital 4Department of Obstetrics and Gynaecology, Calvary Hospital 5John James Medical Centre, Deakin, - - 2014
A 26-year-old Indian lady G2P0 presented at 33 weeks gestation complaining of itch. Liver function tests revealed an elevated alkaline phosphatase (ALKP) of 2983 U/L (normal range 20-110) which on fractionation was a placental or placental-like isoenzyme. All other investigations, including fetal ultrasound, were normal. Labour was induced at 37 weeks ...
Cheung Annie N Y AN Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong - - 2014
Extensive use of ultrasound in early pregnancy has given rise to increased diagnostic dilemma, particularly the differential diagnosis of early complete mole, partial mole and abnormal nonmolar villous lesions. The rare entities of placental mesenchymal dysplasia, twin pregnancy with one complete mole further pose problems. Overdiagnosis of hydatidiform mole in ...
Faye-Petersen Ona Marie OM Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, - - 2014
There is mounting evidence that several placental pathologic entities associated with fetal intrauterine growth restriction and poor and recurrent pregnancy outcomes reflect disruption of mechanisms of immune tolerance normally operative during pregnancy. This presentation update will include an overview studies that have yielded evidence of the role of alloimmune mechanisms, ...
Petukhova N L NL ART Clinic "Test-tube babies" , Moscow , - - 2014
Abstract This study of infertile women prior in vitro fertilization (IVF) is focused at the genetic and acquired thrombophilia before the IVF program, the identification of the frequency of occurrence of thrombophilia in them, the impact of thrombophilia of the offensive, the course and outcome of pregnancies, to improve the ...
Glasier Anna A Department of Obstetrics and Gynaecology, University of Edinburgh , Edinburgh , Scotland - - 2014
Abstract Unintended pregnancy is an important public health problem worldwide. Unwanted pregnancies may end in induced abortion (legal or illegal, safe or unsafe) or in childbirth. In many parts of the world both can be life threatening. Even where both are safe, abortion is distressing for all concerned while unwanted ...
Cohen J J Department of Gynecology and Obstetrics, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris Université Pierre et Marie Curie Paris 6, France - - - 2014
The main objective was to confirm with modern tools the former assertion that there is a vascular resistance gradient along the umbilical cord. We performed a prospective observational study in a population of women with third trimester monofetal and uncomplicated pregnancies during two months. Pulsatility Index and Resistance Index were ...
Visentin Silvia S Department of Woman's and Child's Health, Maternal-Fetal Medicine Unit, University of Padua School of Medicine, Padua, Italy (S.V., F.G., D.T., V.Z., G.A., E.C.); and Clinic of Obstetrics and Gynecology, Department of Experimental Clinical and Medical Sciences, University of Udine, Udine, Italy - - 2014
To investigate whether antenatal recognition of small-for-gestational-age (SGA) fetuses with normal maternal and fetal Doppler values delivered after 34 weeks' gestation is associated with changes in the risk of adverse maternal and neonatal outcomes. In this retrospective study, we included 313 singleton SGA fetuses and 313 appropriate-for-gestational-age control fetuses born ...
Bromley Bryann B Diagnostic Ultrasound Associates, PC, Boston, Massachusetts USA (B.B., T.D.S., Y.G., B.R.B.); Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts USA (B.B., B.R.B.); Departments of Obstetrics and Gynecology (B.B., T.D.S., Y.G., R.S.N., B.R.B.) and Radiology (B.B., T.D.S., B.R.B.), Brigham and Women's Hospital, Boston, Massachusetts USA; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts USA (J.L.); and Harvard Vanguard Medical Associates, Boston Massachusetts USA (R.S.N.). - - 2014
The purpose of this study was to evaluate the importance of second-trimester "soft markers" for trisomy 21 after an 11- to 14-week aneuploidy screening scan. We conducted a retrospective cohort study of consecutive patients referred for measurement of the nuchal translucency (NT) as part of a screening protocol for aneuploidy. ...
Bromley Bryann B Diagnostic Ultrasound Associates, PC, Boston, Massachusetts USA (B.B., T.D.S., Y.G., B.R.B.); Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts USA (B.B., B.R.B.); Departments of Obstetrics and Gynecology (B.B., T.D.S., S.N., Y.G., B.R.B.) and Radiology (B.B., T.D.S., B.R.B.), Brigham and Women's Hospital, Boston, Massachusetts USA; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts USA (J.L.); and Harvard Vanguard Medical Associates, Boston, Massachusetts USA (R.S.N.). - - 2014
The purpose of this study was to determine whether first-trimester aneuploidy screening sonography initially performed by credentialed sonographers was useful for detecting fetal anomalies between 11 and 14 weeks' gestation. We conducted a retrospective cohort study of consecutive patients referred to a private ultrasound facility between January 1, 2008, and ...
Ugurlucan Funda Gungor FG Istanbul University Istanbul Medical School, Department of Obstetrics and Gynecology, Istanbul, - - 2014
To evaluate the feasibility of umbilical cord scanning during the second-trimester sonographic examination, we looked at the method of scanning, the findings, and the time spent. Five hundred forty-nine singleton pregnancies were evaluated at 18-23 weeks' menstrual age with two-dimensional sonography (US). Color Doppler US was used when needed. The ...
Matinnia Nasrin N Department of Community Health, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia, - - 2014
Pregnancy- and childbirth-related fears are common psychological concerns and the primary reasons for requesting caesarean section (CS). We aimed to examine the content of maternal fear and the associated demographic factors in a sample of Iranian primigravidae. A randomly selected sample of primigravidae (n = 342) was recruited in four health care ...
Croft Adam P AP Department of Renal Immunobiology, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, - - 2014
Pregnancy in patients with anti-neutrophil cytoplasm antibody-associated vasculitis is reportedly associated with a high risk of fetal and maternal complications. Here we describe the outcome of pregnancies in patients with granulomatosis with polyangiitis and microscopic polyangiitis at five centers in the United Kingdom using a retrospective case review of all ...
Wassenaar Trudy M TM Molecular Microbiology and Consultants, Zotzenheim, - - 2014
Novel findings in microbiology question the long-standing paradigm that a healthy pregnancy implies a sterile uterus. It now seems that the placenta is frequently colonized with bacteria, and a placental microbiome has been identified. Recent literature findings are summarized here, and an attempt is made to separate pathological bacterial presence ...
Hudeček Robert R Department of Obstetrics and Gynaecology, Masaryk University and University Hospital Brno , Brno, Czech Republic - - 2014
Background: An ectopic pregnancy within a Cesarean scar represents a rare type of extrauterine pregnancy in which the fertilized egg nidates in the myometrium of the uterine wall within a scar left from a previous Cesarean delivery. An unrecognized growing Cesarian scar pregnancy may result in uterine rupture, uncontrollable metrorrhagia, ...
Rab Attila A Telki Hospital, Telki, - - 2014
Abstract Objective: The gene expression of transforming growth factor beta-1 (TGF-β1) in human placental samples obtained from pregnancies with small for gestational age fetuses (SGA) was compared to those of normal pregnancies. Methods: In 2011 placental samples from 101 pregnancies with SGA and from 140 normal pregnancies were obtained for ...
Sun Libo - - 2014
Neonatal mortality reduction in China over past two decades was reported from nationwide sampling surveys, however, how high risk pregnancy affected neonatal outcome is unknown. The objective of this study was to explore relations of pregnancy complications and neonatal outcomes from a regional birth population. In a prospective, cross-sectional survey ...
Payne Matthew S - - 2014
This study tested if second trimester amniotic fluid cytokine levels, Ureaplasma sp. colonisation and sexual activity predict preterm birth and explain the differential preterm birth rates in Chinese compared to Australian women. Amniotic fluid was collected by amniocentesis (Chinese 480, Australian 492). Cytokines were measured by multiplex assay and Ureaplasma ...
Shin Jung-A JA Department of Anatomy, School of Medicine, Ewha Womans University, Seoul, - - 2014
Background: Normal fetal development requires adequate folate levels during pregnancy. Although folate metabolic enzymes have important roles in the maintenance of normal fetal development, the location of folate metabolic enzymes, methionine synthase (MTR) and 5,10-methylenetetrahydrofolate reductase (MTHFR), has not been previously examined. Methods: We investigated the expression of MTR and ...
Li Jian J Department of Clinical Medicine, Medical college of Hunan Normal University, Changsha 410006, - - 2014
Background/Aims: Diabetes is well-known to influence endothelial function. Endothelial function and blood flow regulation might be different in diabetic and non-diabetic pregnancy. However, the impact of umbilical blood flow regulation in gestational diabetes on fetal development is unknown so far. Methods: In a prospective birth cohort study, we analyzed the ...
Al-Gubory Kaïs H - - 2014
Abstract Oxidative stress is associated with decreased female fertility and adversely affects prenatal development. Mammalian cells have developed a network of enzymatic and non-enzymatic antioxidant defence systems to prevent oxidative stress. Little attention has been paid to the antioxidative pathways in placentas of normal and disturbed pregnancies, leaving a gap ...
Shamsa A A Department of Obstetrics and Gynaecology, Westmead Hospital , Westmead, NSW , - - 2014
The aim of this study was to review the incidence, indication, management and complications of peripartum hysterectomy (PH) in a tertiary level hospital over a decade. A retrospective review of all cases of PH performed at Westmead Hospital, Western Sydney, 2003-2012, was undertaken. PH was defined as hysterectomy performed after ...
Liorni Ilaria I CNR Consiglio Nazionale delle Ricerche, Istituto di Elettronica e di Ingegneria dell'Informazione e delle Telecomunicazioni IEIIT (CNR National Research Council of Italy, Institute of Electronics, Computer and Telecommunication Engineering), Piazza Leonardo da Vinci, Milano, Italy; Dipartimento di Elettronica, Informazione e Bioingegneria DEIB (Department of Electronics, Information and Bioengineering), Politecnico di Milano, Piazza Leonardo da Vinci, Milano, - - 2014
In this paper, fetal exposure to uniform magnetic fields (MF) with different polarizations is quantified at 50 Hz. Numerical computations were performed on high-resolution pregnant models at 3, 7, and 9 months of gestational age (GA), that distinguish a high number of fetal tissues. Fetal whole-body and tissue-specific induced electric fields ...
Sung Joyce F JF Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Colorado Denver, Aurora, - - 2014
Objective To determine whether hyperglycemic excursions detected by continuous glucose monitoring (CGM) correlate with birth weight percentile and other pregnancy outcomes, and whether CGM correlates better with these outcomes than a single glucose value from a 1-hour glucose challenge test (GCT). Study Design This was a prospective observational study of 55 pregnant ...
Shreffler Karina M KM Department of Human Development and Family Science, Oklahoma State University, 700 N. Greenwood Ave., Tulsa, OK, 74106, USA, - - 2014
How stable are women's pregnancy intentions across their reproductive lifespans? Are there demographic, social, or attitudinal characteristics that are associated with differing pregnancy intentions patterns? Patterns of intendedness across pregnancies were examined using a sample of 3,110 women ages 25-45 who have been pregnant at least twice from the National ...
Sananès Nicolas N Department of fetal medicine, Strasbourg teaching hospital, - - 2014
Abstract Objective: The monkey model is the best model to investigate some physiological response to the fetal transitory tracheal occlusion but it has never been described in macaca monkeys. The aim of this study was to evaluate the feasibility of fetal endoscopic tracheal occlusion (FETO) in a non-human primate model. ...
Aviram Amir A Rabin Medical Center, Helen Schneider Hospital for Women , Petah Tikva , Israel - - 2014
Abstract Objective: We aimed to evaluate whether pre-recognition of small for gestational age (SGA) at late preterm or term pregnancies, has an impact on pregnancy outcome. Methods: Retrospective analysis of SGA newborns, stratified to those with suspected or unsuspected IUGR according the sonographic estimated fetal weight (EFW), below the 10th ...
Titapant Vitaya V Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
The aim of this study was to explore the effects of prenatal fetal diagnoses of non-lethal anomalies on the psychological well-being of pregnant women throughout their pregnancy. Fifty-five pregnant women were asked to complete a questionnaire (the Spielberger State-Trait Anxiety Inventory) to assess their anxiety levels at multiple follow-up visits. ...
Kagan K O KO Department of Obstetrics and Gynaecology, University of Tuebingen, - - 2014
Purpose: To examine combined first trimester screening (FTS), noninvasive prenatal testing (NIPT) and a two-step policy that combines FTS and NIPT in screening for aneuploidy. Materials and Methods: Retrospective study involving 21 052 pregnancies where FTS was performed at the Praxis Praenatal.de in Duesseldorf, Germany. In each case, the sum risk ...
Pala H G HG Division of Perinatology, Department of Obstetrics and Gynecology, Celal Bayar University School of Medicine , Manisa , - - 2014
The aim of this study is to evaluate the relationship between three-dimensional (3D) ultrasound measurements of placenta at 11-13(6) weeks' gestation and maternal serum levels of pregnancy associated plasma protein-A (PAPP-A), free beta human chorionic gonadotrophin (fβhCG), Doppler parameters in early pregnancy. This prospective study consisted of 334 singleton pregnancies ...
Chang Abraham A Stanford Health Care, Palo Alto, CA, - - 2014
Systematically review the literature assessing outcomes of acute myeloid leukemia (AML) treatment during pregnancy. A Pubmed literature search (January 1969 to June 2014) for articles written about AML and pregnancy, and bibliographies/citations of previously published reviews. Articles written in the English language that administered active AML chemotherapy during pregnancy were ...
Stocker L J LJ University of Southampton, Faculty of Medicine, Academic Unit of Human Development and Health, - - 2014
To investigate the incidence of congenital lung malformations over the past 19 years. Congenital lung malformations (CLM) are a heterogeneous group of lung abnormalities. The antenatal diagnosis is important for fetal and neonatal management but there have been no studies examining whether the reported incidence of this abnormality is constant. ...
Fruscalzo A A Clinic of Obstetrics and Gynecology, DISM, AOU, "SM della Misericordia'" of Udine, P.le SM della Misericordia 15, 33100, Udine, Italy, - - 2014
Retinol (ROH) is an essential micronutrient required for normal fetal development and an essential molecule for antioxidant processes. To investigate the putative role of ROH as a marker of preeclampsia in early second trimester amniotic fluid (AF). Case-control study comparing the concentration of ROH and other antioxidants such as uric ...
Chen Lei-Shih LS Department of Health and Kinesiology, Texas A&M University, College Station, - - 2014
In the United States, prenatal genetic testing (PGT) for Autism Spectrum Disorders (ASD) is currently available via clinical genetic services. Such testing may inform parents about their unborn child's risk for ASD, prepare parents for the birth of an affected infant, and allow them to arrange for early interventions. Although ...
Quezada Maria Soledad MS Harris Birthright Research Centre for Fetal Medicine, King's College, London, - - 2014
To examine the performance of cell-free (cf)DNA testing for trisomies 21, 18 and 13 in a general population at 10-11 weeks' gestation. In 2,905 singleton pregnancies prospective screening for trisomies was performed by chromosome-selective sequencing of cfDNA in maternal blood at 10-11 weeks and by the combined test at 11-13 ...
Macdonald-Wallis Corrie C aMRC Integrative Epidemiology Unit at the University of Bristol bSchool of Social and Community Medicine, University of Bristol, Bristol cCentre for Statistical Methodology dDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London eSchool of Medicine, University of Glasgow, Glasgow, - - 2014
Pregnancy is a period of considerable change in blood pressure, with an early pregnancy decrease followed by a late pregnancy rise. High blood pressure in pregnancy is associated with adverse perinatal outcomes for the mother and offspring. We aimed to define normal ranges of blood pressure across gestation. We used ...
Dumitrescu Adina A Department of Obstetrics, Gynecology and Reproductive Sciences (GWA, EDA), Center for Studies in Reproduction, University of Maryland School of Medicine, Baltimore, MD, 21201 and Departments of Obstetrics and Gynecology and Physiological Sciences (AD, GJP), Eastern Virginia Medical School, Norfolk, VA, - - 2014
We have previously shown that estrogen selectively suppresses growth of the fetal zone of the baboon fetal adrenal cortex, which produces the C19-steroid precursors, e.g. dehydroepiandrosterone sulfate (DHAS), that are aromatized to estrogen within the placenta. In the present study, we determined whether fetal adrenal expression of cell cycle regulators ...
Girardi G G 1] MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK [2] Lupus Research Unit, The Rayne Institute, King's College London St Thomas' Hospital, London, - - 2014
In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of complement activation in placenta and foetal brain in vivo in utero. Using this method, we found that anti-complement C3-targeted ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles bind within the inflamed placenta and foetal brain cortical ...
Rada Cara C CC Washington - - 2014
Proper placental perfusion is essential for fetal exchange of oxygen, nutrients, and waste with the maternal circulation. Impairment of utero-placental vascular function can lead to pregnancy complications, including preeclampsia and intrauterine growth restriction. Potassium channels have been recognized as regulators of vascular proliferation, angiogenesis, and secretion of vasoactive factors, and ...
Freud Lindsay R LR Department of Cardiology, Boston Children's Hospital, Harvard Medical - - 2014
To better understand the natural history and spectrum of fetal aortic stenosis (AS), we aimed to 1) determine the prenatal diagnosis rate of neonates with critical AS and a biventricular (BV) outcome; and 2) describe the findings at fetal echocardiography in prenatally diagnosed patients. A multi-center, retrospective study was performed ...
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