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Kolb Andreas F - - 2012
Development of the mammary gland requires the coordinated action of proteolytic enzymes during two phases of remodelling. Firstly, new ducts and side-branches thereof need to be established during pregnancy to generate an extensive ductal tree allowing the secretion and transport of milk. A second wave of remodelling occurs during mammary ...
Montani Daniela Antunes - - 2012
This research proposed to study the changes in lipid composition in cumulus cells (CCs) from women who achieved pregnancy compared with women who did not, after in vitro fertilization treatment. This approach has the potential to provide novel information on the lipid metabolism of the CCs and as an additional ...
Schneider H - - 2012
BACKGROUND: Pregnancies in women with severe relapsing-remitting multiple sclerosis treated with natalizumab constitute a major challenge, because withdrawal of the drug may cause relapses but continuation might have unknown effects on the infantile immune system. AIMS OF THE STUDY: To identify the impact of maternal natalizumab treatment during pregnancy on ...
Gasparović Vesna Elvedi - - 2012
The purpose of this study was to determine acceptability of the nucleated red blood cells counts (NRBC) as early prognostic parameter for adverse outcome in preterm neonates born from pregnancies complicated with severe preeclampsia. We analysed 77 premature newborns who were born from pregnancies with severe preeclampsia during eight years ...
Eszes N - - 2012
Asthmatic inflammation during pregnancy poses a risk for maternal and fetal morbidities. Circulating T cell immune phenotype is known to correlate with airway inflammation (detectable by fractional concentration of nitric oxide present in exhaled breath (FENO)) in non-pregnant allergic asthmatics. The aim of this study was to assess the relationship ...
Mouawia Hussein - - 2012
This study sought to determine whether a reliable non-invasive prenatal diagnosis (NI-PND) of cystic fibrosis (CF) or spinal muscular atrophy (SMA) can be achieved through analysis of circulating fetal trophoblastic cells (CFTC). The kinetics of CFTC circulation were also studied. CFTC were isolated by isolation by size of epithelial tumour/trophoblastic ...
Silasi Michelle - - 2012
A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical ...
Wieciech Iwona - - 2012
The aim of this study was to determine the immunolocalization and expression of the androgen receptor (AR) in the pig placenta and umbilical cord during pregnancy following exposure to flutamide, a non-steroidal antiandrogen, at its various stages. Pregnant pigs were injected with flutamide at a daily dose of 50mg/kg body ...
Hasanzadeh Malihe - - 2012
Aim:  Considering that Ki-67 is a proliferative marker in molar pregnancies and the possible progression of these kinds of pregnancies to gestational trophoblastic neoplasia (GTN), we decided to evaluate the rate of expression of this marker in patients with uneventful hydatidiform moles and GTN. Moreover, we determined the predictive value ...
Kowalczyk-Zieba Ilona - - 2012
We examined whether the CL is a site for lysophosphatidic acid (LPA) synthesis and/or a target for LPA action in the bovine reproductive tract. LPA concentrations in the CL tissue increased towards the end of the cycle and were stable during early pregnancy. No changes in the expression of LPA ...
Nurani Raisha - - 2012
Objective: To identify the incidence of fetal heart rate (FHR) accelerations in the second stage of labor and the role of fetal electrocardiograph (ECG) in avoiding misidentification of maternal heart rate (MHR) as FHR. Design: Retrospective observational study. Setting: University hospital labor ward, London, UK. Sample: Cardiotocograph (CTG) tracings of ...
Tranquilli Andrea L - - 2012
Abstract Although central to the cardinal movements that lead to the delivery of the fetus, the second stage of labor is often neglected from a cultural and clinical viewpoint. In this phase, acquisition is more difficult, and reading and interpretation may not be the same as in the active first ...
Schwake D - - 2012
Our objective was to examine the feasibility of reverse breech extraction to disengage fetal head from the pelvis at second stage caesarean section (CS). A total of 50 consecutive women with singleton term pregnancies undergoing urgent CS at second stage were retrospectively evaluated. A total of 29 were delivered by ...
de Ziegler Dominique - - 2012
It has been two decades since pregnancies have been obtained through in vitro maturation (IVM) of germinal vesicle-stage oocytes retrieved from non-stimulated ovaries. This technique first offered in PCOS cannot be recommended today in this indication because the results do not match those of regular ART, and new GnRH antagonist and ...
Chandra Surabhi - - 2012
Pregnancy is a state characterized by many physiological hematological changes, which may appear to be pathological in the non-pregnant state. The review highlights most of these changes along with the scientific basis for the same, as per the current knowledge, with a special reference to the red blood and white ...
Papantoniou Nikos - - 2012
Abstract Fetal anemia, mainly due to red cell alloimmunization, is still a significant cause of fetal and neonatal mortality and morbidity. The focus of current clinical research has shifted from an invasive approach to non-invasive management and treatment of affected pregnancies, and the progress in this field is associated with ...
Frey Heather A - - 2012
Objective To estimate maternal, neonatal, and labor outcomes associated with delayed pushing.Study Design A retrospective cohort study of all consecutive women admitted to a single institution in labor at term who reached the second stage of labor. Pregnancies with multiple fetuses or major anomalies were excluded. Delayed pushing was defined ...
Torkildsen Erik A - - 2012
Objective. To examine how well ultrasound assessed occipitoposterior (OP) position or high sagittal (HS) position in primiparous women with a prolonged first stage of labor predicts a vaginal delivery and the duration of labor. Design. Prospective observational study. Setting. Stavanger University Hospital, a secondary referral center in Norway. Population. 105 ...
Piccoli Barbara Giorgina - - 2012
BackgroundChronic kidney disease (CKD) has a high prevalence in pregnancy. In a period of cost constraints, there is the need for identification of the risk pattern and for follow-up.MethodsPatients were staged according to K-DOQI guidelines. The analysis was prospective, January 2000-June 2011. Two hundred and forty-nine pregnancies were observed in ...
Pritchard Stephanie - - 2012
During pregnancy, fetal cells cross into the maternal organs where they reside postpartum. Evidence from multiple laboratories suggests that these microchimeric fetal cells contribute to maternal tissue repair after injury. In mouse models, most injury experiments are performed during pregnancy; however, in a clinical setting most injuries or diseases occur ...
Saadai Payam - - 2012
Maternal-fetal cellular trafficking (MFCT) during pregnancy leads to the presence of maternal cells in the fetus and of fetal cells in the mother. Since this process may be altered in cases of pregnancy complications, we asked whether open fetal surgery leads to changes in microchimerism levels. We analyzed maternal and ...
Reinhard Joscha - - 2012
OBJECTIVE: The objective of this study was to assess the fetal heart rate (FHR) signal quality of non-invasive abdominal fetal electrocardiogram (fECG) in comparison to the Doppler ultrasound cardiotocogram (CTG) during the first and second stage of labour. STUDY DESIGN: This was a prospective observational study of non-invasive fECG using ...
Ouzounian Joseph G - - 2012
The major adaptations of the maternal cardiovascular system that progress throughout gestation may unmask previously unrecognized heart disease and result in significant morbidity and mortality. Most of these changes are almost fully reversed in the weeks and months after delivery. Hemodynamic changes during pregnancy include increased blood volume, cardiac output ...
Valle Marcello - - 2012
The role of cryopreservation in assisted reproductive technology programs has increased within the last years allowing the transfer of a limited number of embryos and the storage of the remaining for future use. The reduction in the number of transferred embryos decreases the frequency of multiple pregnancy rates and of ...
Siniza Swetlana - - 2012
This study provides a contribution to the reconstruction of the eulipotyphlan placental morphotype and also may help resolving a long-standing conflict about the interhaemal barrier in moles. As detailed descriptions of talpid placentation, only available for Talpa europaea and Scalopus aquaticus, led to a controversial debate on the nature of ...
Stout Tae - - 2012
During the past 15 years, embryo transfer (ET) has become increasingly widespread within the sport-horse breeding industry. At present, however, the vast majority (>95%) of horse embryos are transferred fresh or after chilled storage for up to 24 h, whereas cryopreservation is rarely employed despite its obvious potential for simplifying recipient mare ...
Kumtepe Yakup - - 2012
A 36-year-old para 2 woman with Pelvic Organ Prolapse Quantification (POP-Q) stage III anterior prolapse and stress urinary incontinence (SUI) was treated using Polypropylene monofilament anterior vaginal mesh kit. She conceived 3 months after mesh replacement. During pregnancy and after delivery, patient satisfaction was achieved in terms of symptom relief, and ...
Pinborg Anja - - 2012
Worldwide freezing and thawing of embryos has been increasingly used since the first infant was born as a result of this technique in 1984. The use of frozen embryo replacement (FER) currently even exceeds the number of fresh cycles performed in some countries. This article discusses the pros and cons ...
Hanazawa K - - 2012
A novel, minimally invasive, transabdominal embryo collection method (transabdominal method) was developed as an alternative to a standard abdominal incision for embryo collection in the common marmoset. The abdominal incision method was used for 304 flushes using 36 female animals, whereas the transabdominal method was used for 488 flushes using ...
Yoldemir Tevfik - - 2012
Objective: To determine whether older women with a poor response to follicular stimulation achieve pregnancy results that are comparable to those of younger poor responders. Methods: Two hundred five women undergoing in vitro fertilization treatment at the Fertility Unit in the Royal Prince Alfred Hospital in Sydney, Australia were selected ...
Sepulveda Waldo - - 2012
The purpose of this report is to describe the prenatal sonographic findings in fetuses with hydranencephaly diagnosed during the early stages of disease. Four cases with characteristics of hydranencephaly were retrospectively identified from 2 Latin American fetal medicine referral centers. Information on maternal demographics, sonographic findings, antenatal courses, and pregnancy ...
Ishimaru Tomohiro - - 2012
Pregnancy-induced hypertension or pre-eclampsia is a major disorder that may result in serious complications for the mother and fetus. It is characterized from maternal hypertension in late pregnancy and peripheral tissue damage, including kidney, heart and placenta, and the fetus suffers from intrauterine growth retardation (IUGR) and high perinatal mortality. ...
McDonald Birgitte I - - 2012
Abstract Life-history theory predicts that selection will favor optimal levels of parental effort that balance benefits of current reproduction with costs to survival and future reproduction. The optimal level of effort depends on parental traits, offspring traits, and provisioning strategy. Additionally, how these factors influence effort may differ depending on ...
Eftekhar Maryam - - 2012
PURPOSE: The aim of our study was to compare the transfer of embryos that are cryopreserved in cleavage stage after thawing with the transfer of embryos after thawing and culture in sequential media until blastocyst formation. METHODS: In this prospective clinical study, we have evaluated 134 cycles of ART treatment ...
Shi Wenhao - - 2012
OBJECTIVE: To evaluate the safety of vitrification of embryos by comparing the perinatal outcome of vitrified day 3 ETs with fresh cleavage-stage ETs. DESIGN: Retrospective analysis. SETTING: Assisted reproduction center. PATIENT(S): A total of 806 women with 494 infants delivered were included. INTERVENTION(S): Supernumerary embryos and embryos of patients at ...
Sembon S - - 2012
In livestock, parthenogenic embryos are simple to produce, but androgenetic embryos have been successfully produced only in sheep and cows. In the present study, matured porcine oocytes were enucleated by micromanipulation and then fertilized with sperm in vitro, thereby producing porcine androgenetic embryos. Porcine androgenetic embryos, which had only sperm ...
Kovacs Peter - - 2012
OBJECTIVE: Embryo transfer (ET) is an important last step during the process of IVF. Over the years much has been learned about the importance of the details of this procedure including the potential impact of transfer depth on outcome. The objective of our study was to evaluate whether transfer depth ...
Stylianou Christos - - 2012
This study aims to provide a first evaluation of the morphological embryo grading scheme proposed in the British Fertility Society and Association of Clinical Embryologist joint guidelines for elective single embryo transfer. Pregnancy data were obtained from a cohort of patients treated at St. Mary's Hospital in Manchester, UK, between ...
Chen Man-Ling - - 2012
The aim of this study was to investigate simultaneous laparoscopy in endometriotic women with infertility undergoing in vitro fertilization (IVF). Forty-seven infertile patients with endometriosis were enrolled in this retrospective study and underwent IVF cycles in a university affiliated hospital. The chemical pregnancy, clinical pregnancy and live birth rates were statistically ...
McGready Rose R Shoklo Malaria Research Unit, PO Box 46, Mae Sot Tak 63110 Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, - - 2012
To determine if reported lower plasma concentrations of artemisinin derivatives for malaria in pregnancy result from reduced oral bioavailability, expanded volume of distribution or increased clearance. In a sequentially assigned crossover treatment study, pregnant women with uncomplicated falciparum malaria received i.v. artesunate (i.v. ARS) (4mgkg(-1) ) on the first day ...
Opøien Hans Kristian - - 2012
OBJECTIVE: To assess success rates of IVF and intracytoplasmic sperm injection in women with various stages of endometriosis. DESIGN: Retrospective cohort study. SETTING: Reproductive medicine unit in a university hospital. PATIENT(S): Infertile women (n = 2,245) with various stages of endometriosis or tubal factor infertility. INTERVENTION(S): IVF or intracytoplasmic sperm ...
Brenner Benjamin - - 2012
Haematological cancer in pregnancy, although rare, poses a substantial risk to both mother and fetus. Hodgkin's lymphoma is the most common, followed by non-Hodgkin lymphoma and acute leukaemia. Diagnosis of haematological cancers is challenged by an overlap of the disease and gestation-related symptoms and limitations of imaging studies in pregnancy. ...
Morice Philippe - - 2012
Cervical and ovarian cancers are the most common gynaecological cancers diagnosed during pregnancy. In early-stage cervical cancer during the first and at the beginning of the second trimester, the two main considerations for management of the patient are the tumour size (and stage) and nodal staging. MRI and laparoscopic lymphadenectomy ...
Nguyen Cheri P - - 2012
It is not uncommon to encounter situations in which radiologic examinations are necessary for accurate diagnosis and effective treatment of an expectant mother. The potential deleterious health consequences to the developing embryo and fetus from in utero irradiation include fetal death, congenital malformations, growth retardation, and carcinogenic and mutagenic effects. ...
Alvis Jeffrey S - - 2012
Neurologic complications and conditions associated with pregnancy are rare. Frequently, presenting symptoms of neurologic conditions are nonspecific and can overlap with normal symptoms of pregnancy. As a result, clinical assessment can be insufficient to differentiate symptoms of a normal pregnancy from a neurologic disorder. It is imperative that the radiologist ...
Sermondade Nathalie - - 2012
Some patients in IVF programmes repeatedly display an abnormal embryonic development characterized as soon as day 2 post fertilization by a high rate (>60%) of highly fragmented embryos (⩾40% of cytoplasmic fragments) leading to recurrent IVF failures. This study postulated that, for various maternal reasons, some embryos were unable to ...
Dunkel Schetter Christine - - 2012
PURPOSE OF REVIEW: To briefly review results of the latest research on the contributions of depression, anxiety, and stress exposures in pregnancy to adverse maternal and child outcomes, and to direct attention to new findings on pregnancy anxiety, a potent maternal risk factor. RECENT FINDINGS: Anxiety, depression, and stress in ...
Xu Jin - - 2012
PURPOSE OF REVIEW: Acupuncture has a growing clientele during pregnancy, delivery and the puerperium for an ever increasing list of indications. Objective evidence for its benefit is necessary to establish its roles in current practice. RECENT FINDINGS: For many of the current uses, randomized studies when conducted using at least ...
Majithia Raj - - 2012
Symptoms of gastro-oesophageal reflux disease (GORD or GERD) are estimated to occur in 30-50% of pregnancies, with the incidence approaching 80% in some populations. As with many other conditions in pregnancy, medical therapy with pharmaceutical agents is a concern, as the potential teratogenicity of medications is not well known. Although ...
Soede N M - - 2012
Three intermittent suckling (IS) regimes were evaluated for their effects on lactational oestrus and subsequent fertility. Control sows were weaned (CW; n=38) at d 26±2 of lactation. In IS19-7D (n=40) and IS19-14D (n=42) sows, IS started at d 19±1 of lactation and sows were weaned 7 or 14d later. In ...
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