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Kuzmin A A Rostov Scientific Research Institute of Obstetrics and Pediatrics, Ministry of Health of the Russian Federation , Rostov-on-Don , - - 2014
Abstract Study objective: Tubal factor accounts for 25-30% of cases of female infertility. Laparoscopy "Gold Standard" for tubal evaluation. However, it is known that during the initial infection of the fallopian tube mucosal damage occurs, a condition which plays a decisive role in reproduction. In this prospective randomized study, 468 ...
Wong Lf L Department of Obstetrics and Gynecology, University of Utah, USA Intermountain Healthcare, USA - - 2014
Evidence from basic science studies supports a causative relationship between antiphospholipid antibodies (aPL) and recurrent early miscarriage (REM) (prior to 10 weeks of gestation). However, human studies have not consistently found a relationship between aPL and REM. Members of the Obstetric Task Force of the 14th International Congress on Antiphospholipid ...
Wang Min M Reproductive Medical Center, International Peace Maternity and Child Health Hospital Affiliated, Shanghai Jiaotong University, Shanghai, People's Republic of - - 2014
To investigate how effectively density gradient centrifugation (DGC) improves sperm nuclear integrity and to determine whether the sperm chromatin dispersion (SCD) test of sperm nuclear integrity in native or DGC-treated semen can predict the outcome of assisted reproductive technology (ART) in couples undergoing intracytoplasmic sperm injection (ICSI). The DNA integrity ...
Li Yi Y Reproductive Medicine Research Center, Memorial Hospital of Sun Yat-Sen University, 107 Yan-Jiang-Xi Road, Guangzhou, 510120, People's Republic of - - 2014
To explore the optimal timing for hCG triggering by investigating the impact of different proportion of dominant follicles on the oocyte developmental competence. One hundred ninety-eight infertile women were divided into three groups according to the proportion of dominant follicles on hCG day: (1) low: <15 % (n = 66); (2) middle: 15-27 % ...
Czech-Szczapa Barbara B Department of Preventive Medicine, Poznan University of Medical Sciences (PUMS), ul.Smoluchowskiego 11, Poznan, - - 2014
Abstract Objective: The aim of the study was to assess disordered eating attitudes and other related factors in mothers of newborns requiring Neonatal Intensive Care Unit (NICU) admission compared to those of mothers who delivered healthy infants. Methods: An anonymous self-report study conducted among 199 mothers of newborns hospitalized in ...
Zheng Yu Y Reproductive Medicine Center, Tongji Medicine College, Tongji Hospital, Huazhong University of Science and Technology , Wuhan , - - 2014
Abstract The aim of this retrospective cohort study was to investigate which preparation method is optimal for frozen-thawed embryo transfer (FET) treatment. Analyses were performed on 3160 FET cycles, including 654 cycles with a natural cycle (NC) protocol and 2506 cycles with an artificial cycle (AC) protocol. The primary outcome ...
Liang Pei-Yan PY School of Chemical Biology & Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen, China; Shenzhen Key Laboratory of Reproductive Immunology for Peri-implantation, Fertility Center, Shenzhen Zhongshan Urology Hospital, Shenzhen, China; Shenzhen Zhongshan Institute for Reproduction and Genetics, Shenzhen, - - 2014
To investigate alterations of circulating lymphocyte subsets in women undergoing controlled ovarian stimulation (COS) and survey their relations with pregnancy outcome. Fifty-one women were included in this study, of which 24 women were successfully pregnant in the index IVF cycle (the successful pregnancy group, sPG) and 27 women failed to ...
Adekola Henry H Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland and Detroit, Michigan, - - 2014
Abstract Objective: Endocan, a dermatan sulphate proteoglycan produced by endothelial cells, is considered a biomarker for endothelial cell activation/dysfunction. Preeclampsia (PE) is characterized by systemic vascular inflammation, and endothelial cell activation/ dysfunction. Therefore, the objectives of this study were to determine if: 1) plasma endocan concentrations in PE differ from ...
Hattori Hiromitsu H Kyono ART Clinic, Mitsui-Seimei, Sendai Honcho Bl, 3F, 1-1-1 Honcho, Aoba-ku, Sendai, Miyagi, 980-0014, - - 2014
To examine the impact on development of derived embryos from smooth endoplasmic reticulum clusters (SERC) in human metaphase II (MII) oocytes. Retrospective analysis at Kyono ART Clinic. Comparison of embryological development, pregnancy, live birth and fetal malformation between oocytes with SERC (the SERC(+) group) and those without (the SERC(-) group) ...
Yeung Tracy Wing Yee TW Department of Obstetrics & Gynecology, The University of Hong Kong, Hong Kong - - 2014
Does endometrial injury in the cycle preceding ovarian stimulation for in vitro fertilization (IVF) improve the ongoing pregnancy rate in unselected subfertile women? Endometrial injury induced by endometrial aspiration in the preceding cycle does not improve the ongoing pregnancy rate in unselected subfertile women undergoing IVF. Implantation failure remains one ...
Järvelä Ilkka Y IY Department of Obstetrics and Gynaecology, Oulu University Hospital, PO Box 5000, 90014 Oulu, Finland - - 2014
Are there differences in estrogen and progesterone secretion in singleton pregnancies, up to Week 11, between spontaneous pregnancies, after controlled ovarian hyperstimulation and fresh embryo transfer (COH + ET) and after frozen embryo transfer in a spontaneous cycle (FET)? Serum progesterone and estradiol (E2) concentrations after COH + ET were ...
Cheng Han-Tsung HT Trauma and Emergency Center, China Medical University Hospital, Taichung, Taiwan, ROC, - - 2014
Laparoscopic appendectomy (LA) is the standard treatment of acute appendicitis for the general population; however, there is still some doubt regarding its safety for pregnant patients. Therefore, the purpose of this study is to investigate and compare the maternal outcome of pregnant patients with acute appendicitis following either an open ...
Kasai Junko J Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, Yokohama, - - 2014
To investigate the clinical features of gestational thrombocytopenia (GT) difficult to differentiate from immune thrombocytopenia (ITP) during pregnancy. The January 2000-December 2012 hospital database was analyzed to identify women with ITP or GT (after excluding other possible causes of thrombocytopenia) among those first noted to have platelet counts of less ...
Hill Alexandria J - - 2014
Abstract Objective: The objective of this study was to reproduce and validate the association of group B streptococcus (GBS) colonization resulting in early-term birth (370/7-386/7 weeks' gestation) and lower birth weight, reported in African-American and Caucasian populations, in a Hispanic cohort. Methods: GBS status of women 18-40 years of age ...
Ebrahimi Neda N Motherisk Program, Division of Pharmacology and Toxicology, The Hospital for Sick Children, Canada/University of Toronto, Leslie Dan Faculty of Pharmacy, Canada - - 2014
Safety data on first-trimester natalizumab exposure are scarce, as natalizumab is usually withdrawn three months before pregnancy. The objective of this paper is to investigate the fetal safety of exposure to natalizumab (Tysabri(®)) during the first trimester of pregnancy using disease-matched (DM) and healthy control (HC) comparison groups. A total ...
Safari Somayyeh S Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Bouali Ave, Safaeiyeh, Yazd, - - 2014
The aim was to investigate assisted reproductive technology (ART) outcomes after routine use of EmbryoGlue(®) as a human embryo transfer (ET) medium with high concentration of hyaluronan (HA, hyaluronic acid). A cohort of total 229 patients was retrospectively enrolled for the present study. They were subjected for embryo transfer on ...
Matsuki Yuko Y Center of Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development , Tokyo , - - 2014
Objective. To clarify the clinical significance of antiphospholipid antibody (aPL) profile in patients with obstetric antiphospholipid syndrome (APS). Methods. Clinical records of 13 pregnant patients (15 pregnancies) with obstetrical APS were reviewed over 10 years. Patients who met the Sapporo Criteria fully were studied, whereas those with only early pregnancy ...
Park Yong-Seog YS Laboratory of Reproductive Medicine, Department of Urology, Department of Obstetrics and Gynecology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, 100-380, Republic of Korea, - - 2014
To evaluate the viability of frozen embryos generated by intracytoplasmic sperm injection (ICSI) with frozen testicular spermatozoa. A total of 68 fresh embryo transfer (ET) cycles and 85 subsequent frozen-thawed ET (FET) cycles were grouped according to the source of spermatozoa: fresh testicular spermatozoa (TESE) or frozen-thawed testicular spermatozoa (t-TESE). ...
Kodama Michiko M Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, - - 2014
Malignant germ cell tumors (MGCT) are a rare type of ovarian cancer with poorly understood behavior during pregnancy. This systematic review evaluated feto-maternal outcomes and management patterns of 102 ovarian MGCT-complicated pregnancies identified in PubMed/MEDLINE. Mean age was 25.8. The most common histology type was dysgerminoma (38.2%) followed by yolk ...
Ding Xiaoyan X Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, - - 2014
Preeclampsia (PE) is a multifactorial pregnancy complication. Maternal underlying condition and adverse factors both influence the pathogenesis of PE. Abnormal lipid metabolism as a maternal underlying disease may participate in the occurrence and development of PE. This study aimed to observe the effects of adverse factors on PE-like symptoms of ...
Cooper Sue S Division of Primary Care, University of Nottingham, Nottingham, - - 2014
Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would increase smoking cessation in pregnancy without adversely affecting infants. To compare (1) at delivery, the clinical effectiveness ...
Bianco Carlo C Department of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, - - 2014
Computer-based digital image analysis of tissue samples shows promise both to reduce the subjectivity of traditional manual tissue assessments and potentially to shorten the time required to analyze each sample. The present study used digital image analysis to investigate the histomorphometric parameters and fractal complexity of the equine placenta from ...
Dong Zhe Z Reproductive Medicine Center, Guangzhou Women and Children's Medical Center, No. 9, Jinsui Road, Guangzhou 510623, Guangdong, People's Republic of - - 2014
To compare the reproductive outcomes of frozen-thawed embryo transfer (FET) in nature cycle utilizing monitoring ovulation regimen (MOR) and monitoring progesterone (P) level regimen (MPR). A retrospective analysis of records of 224 women who received FET procedures. MPR was used in 60.3% (135/224) of cycles and MOR in 39.7% (89/224) ...
Vigneswaran Trisha V TV Department of Congenital Heart Disease, Evelina London Children's Hospital, Guy's & St Thomas' Hospitals, Westminster Bridge Road, London SE1 7EH, UK. Electronic address: - - 2014
Transplacental flecainide is an established therapy for fetal supraventricular tachycardia (SVT) but there is a paucity of data regarding the dose-response relationship. The aim of this study was to investigate the relationship between maternal flecainide concentrations, arrhythmia control and adverse fetal effects in fetal SVT. Fetuses with SVT treated with ...
Ardalić Daniela D Narodni Front Clinic of Gynecology and Obstetrics, Belgrade, - - 2014
As a physiological condition closely linked with increased susceptibility to oxidative stress, pregnancy can be further compromised by cigarette smoking. Inadequate nutrition and reduced intake of antioxidants can also disrupt the prooxidant/antioxidant relationship and contribute to oxidative stress. Increased oxidative stress during pregnancy may be involved in several complications of pregnancy, ...
Brzychczy-W Och Monika M Department of Bacteriology, Microbial Ecology and Parasitology, Chair of Microbiology, Jagiellonian University Medical College, Krakow, - - 2014
The main objective of the study was to compare the qualitative and quantitative composition of vaginal and rectal flora in GBS-positive (n=15) and GBS-negative (n=27) pregnant women examined in three subsequent trimesters of their pregnancy. Study samples consisted of vaginal and rectal smears and urine samples. GBS numbers were determined ...
Eleje George Uchenna - - 2014
The elderly primigravida is defined as a woman who goes into pregnancy for the first time at the age of 35 years or older. Progressively, this has become more common in our contemporary society and traditionally such pregnancy is regarded as high risk. This was to determine and compare the ...
Yassaee Fakhrolmolouk F Genomic Research Center, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran ; Infertility and Reproductive Health Research center, Taleghani Hospital, Department of Obstetrics and Gynecology, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Threatened abortion is a common complication of pregnancy. In order to prevent miscarriage in the cases with threatened abortion, this study was conducted to determine whether progesterone suppository is effective in allowing pregnancy to proceed beyond week 20 in women with threatened abortion. This single-blind clinical trial study was done ...
Gao LvFen L Department of Gynecology and Obstetrics, The First Affiliated Hospital of Jinan University, Guangzhou, - - 2014
To assess the efficacy of uterine artery embolization (UAE) combined with dilation and curettage (D&C) within 24hours for the treatment of a cesarean scar pregnancy (CSP), compared with methotrexate and D&C. A retrospective cohort study of 119 women with CSP was conducted at two tertiary hospitals in Guangzhou and Shenzhen, ...
Sun Bo B Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University, Henan, - - 2014
To evaluate basal testosterone (T) levels in women undergoing in vitro fertilization (IVF) cycles and examine the association between basal T levels and ovarian response or IVF pregnancy outcome. We retrospectively analyzed 1413 infertile Chinese women undergoing their first IVF treatment at our institution's reproductive center from March 2011 to ...
Huen I I Centre for Imaging Sciences, University of Manchester, Manchester, UK; The University of Manchester Biomedical Imaging Institute, University of Manchester, Manchester, - - 2014
Magnetic resonance imaging allows the noninvasive observation of Po2 changes between air breathing and oxygen breathing through quantification of the magnetic longitudinal relaxation time T1 . Changes in Po2 are proportional to changes in the longitudinal relaxation rate ΔR1 (where ΔR1  = 1/T1oxygen  - 1/T1air ). Knowledge of this response could inform ...
Shukla Praveen - - 2014
The mechanisms underlying developmental programming are poorly understood but may be associated with adaptations by the fetus in response to changes in maternal environment during pregnancy. We hypothesized that maternal nutrient restriction during pregnancy alters vasodilator responses in fetal coronary arteries. Pregnant ewes were fed a control (100% NRC) or ...
Kumar Ashok A Department of Obstetrics & Gynecology, Maulana Azad Medical College & Lok Nayak Hospital, 13 B, DDA Flats, Ber Sarai, New Delhi, 110016 - - 2014
There are many etiological factors responsible for recurrent abortions. However, no explanation can be identified in approximately 40-50 % of women with recurrent miscarriage (RM). Several studies demonstrated that successful pregnancy is dependant on shifting of maternal immune response from (proinflammatory) Th1 toward (anti-inflammatory) Th2 phenotypes. It was suggested that unexplained ...
Aune Dagfinn D From the aDepartment of Preventive Cardiology, Oslo University Hospital Ullevål, Oslo, Norway; bDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; cDepartment of Epidemiology and Biostatistics, Imperial College, London, United Kingdom; dDepartment of Pediatric Research, Rikshospitalet, Oslo University Hospital, University of Oslo, Oslo, Norway; eSection of obstetrics, Division of Obstetrics and Gynaecology, Rikshospitalet, Oslo University Hospital, Oslo, Norway; and fDepartment of Health Promotion and Education, Loma Linda University, Loma Linda, - - 2014
Physical activity has been hypothesized to reduce the risk of preeclampsia, but epidemiologic studies have not shown consistent results. Therefore, we conducted a systematic review and dose-response meta-analysis of epidemiologic studies. PubMed, Embase, and Ovid databases were searched for case-control and cohort studies of physical activity and preeclampsia up to ...
Seckin Berna - - 2014
To investigate the effect of luteal phase support with vaginal progesterone on pregnancy rates of the gonadotropin-stimulated intrauterine insemination (IUI) cycles in patients with unexplained infertility with regard tofollicular growth. A total of 149 patients with unexplained infertility who underwent 166 recombinant follicle stimulated hormone--stimulated IUI cycles were prospectively randomized ...
Siristatidis Charalampos C Assisted Reproduction Unit, 3rd Department of Obstetrics and Gynecology, University of Athens, Rimini 1, Chaidari, 12642 Athens, Greece. Electronic address: - - 2014
In this report, we propose an intervention capable of improving IVF outcomes in subfertile women with poor ovarian response. This intervention derives from anecdotal data and observations in our daily practice, but most importantly from trials on experimental models and subfertile women with Polycystic Ovarian Syndrome (PCOS). Our hypothesis suggests ...
McDaniel Ian - - 2014
This article considers the objection to abortion that a woman who voluntarily engages in sexual activity is responsible for her fetus and so cannot have an abortion. The conclusion argued for is that the conceptions of responsibility that can ground the objection that are considered do not necessitate a requirement ...
Revelli Alberto A Physiopathology of Reproduction and IVF Unit, Department of Surgical Sciences, University of Torino, St. Anna Hospital, via Ventimiglia 3, 10126, Torino, Italy, - - 2014
This large prospective, randomized study was designed to compare the "mild" protocol with clomiphene citrate, low-dose gonadotropins and a GnRH-antagonist (CC/Gn/GnRH-ant protocol) with the "long" protocol with a GnRH-agonist and high-dose Gn for the controlled ovarian hyperstimulation (COH) of patients with expected poor ovarian responsiveness undergoing IVF. A total of ...
Chau Anthony A aDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston Massachusetts, USA bDepartment of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada cDepartment of Anesthesia, Faculty of Medicine, Harvard Medical School, Boston, Maassachusetts, - - 2014
In many labor and delivery units, the obstetric anesthesiologist is often responsible for managing and stabilizing the acutely septic parturient. The management of maternal sepsis has been summarized previously; this study will focus on the implications of maternal sepsis on the fetus, and ways to optimize fetal outcomes. Although the ...
Verdonk Koen K *Department of Internal Medicine, Division of Vascular Medicine and Pharmacology, Erasmus MC, Rotterdam, The - - 2014
Pregnancy demands major changes of the cardiovascular system, and this involves, among others, activation of the RAAS (renin-angiotensin-aldosterone system), allowing an aldosterone-dependent increase in volume. Remarkably, a relative resistance to the pressor response of AngII (angiotensin II) develops simultaneously to prevent the increase in blood pressure that would normally accompany ...
Proisy Maïa M 1 Department of Imaging, CHU de Rennes-Hôpital Sud, Rennes, - - 2014
OBJECTIVE. This article provides an overview of the typical appearance of biomechanical and physiologic changes in pregnancy and an update on related pathophysiology. Conditions occurring during the childbearing, delivery and postpartum periods will be reported separately. CONCLUSION. Pregnancy causes biomechanical and physiologic changes that may be responsible for a wide ...
Manikandan K K Department of Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, - - 2014
Frusemide use in pregnancy is generally restricted to patients with cardiac decompensation. In the past, maternal administration of oral frusemide had been tried to identify non-functioning fetal kidneys by utilizing the diuretic effect of frusemide on the fetal kidneys. We report a case of primigravida with severe mitral stenosis presenting ...
Mascarenhas Mariano M Reproductive Medicine Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, - - 2014
The overwhelming numbers of twins following assisted reproductive technology (ART) are dichorionic twins, but monochorionic twins account for around 0.9% of post ART pregnancies. The data for post ART-monochorionic pregnancy outcomes are scarce due to the rarity of this condition. Hence, we evaluated the obstetric outcomes of monochorionic and dichorionic ...
Sunkara Sesh Kamal SK King's College London, London, - - 2014
Is there a relationship between ovarian reserve, quantified as ovarian response to stimulation, and miscarriage rate following IVF treatment? There is a strong association between the number of oocytes retrieved and miscarriage rate following IVF treatment, with the miscarriage rate decreasing with an increasing number of oocytes and then levelling ...
Trakakis Eftihios E Third Department of Obstetrics and Gynecology, University of Athens Medical School, Attikon General University Hospital , Athens , Greece - - 2014
Abstract We aim to present the first case of a pregnancy achieved by administering sildenafil (Viagra) to a woman not responding to controlled ovarian hyperstimulation (COH) with the sole use of gonadotropins. A 37-year-old woman underwent COH, as part of an intracytoplasmic sperm injection (ICSI) cycle, with the combination of ...
Kutlusoy Fatma F Department of Obstetrics & Gynecology, Gazi University School of Medicine , Ankara , Turkey - - 2014
Abstract In this study, our objective was to determine the effect of adding estradiol hemihydrate (E2) to progestin (P) for luteal phase support on pregnancy outcome in in vitro fertilization (IVF) cycles with poor response to gonadotropins. Ninety-five women with poor ovarian response who underwent controlled ovarian hyperstimulation (COH) with ...
Hochmeister Sonja S Medical University Graz, Department of Neurology, Graz, - - 2014
Neurofascin was recently reported as a target for axopathic autoantibodies in patients with multiple sclerosis (MS), a response that will exacerbate axonal pathology and disease severity in an animal model of multiple sclerosis. As transplacental transfer of maternal autoantibodies can permanently damage the developing nervous system we investigated whether intrauterine ...
Whitaker-Azmitia Patricia M PM Department of Psychology, Stony Brook University, Stony Brook, NY 11794, United States. Electronic address: - - 2014
Studies show increased autism risk among children born to mothers experiencing obstetrical complications. Although this is usually interpreted as suggesting that the obstetrical complications could be causing autism, it is possible that a single factor could be responsible for both complications and autism. We hypothesized that low levels of the ...
Schleger Franziska F a fMEG Center , University of Tübingen , Tübingen , - - 2014
Numerosity discrimination has been demonstrated in newborns, but not in fetuses. Fetal magnetoencephalography allows non-invasive investigation of neural responses in neonates and fetuses. During an oddball paradigm with auditory sequences differing in numerosity, evoked responses were recorded and mismatch responses were quantified as an indicator for auditory discrimination. Thirty pregnant ...
Guzmán-Gutiérrez Enrique E Group of Research and Innovation in Vascular Health, Facultad de Ciencias de la Salud, Universidad San Sebastian Concepción, Chile ; Facultad de Ciencias de la Salud, Universidad San Sebastián Concepción, - - 2014
Synthesis of thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3), in the human fetus starts from 17 to 19th weeks of gestation. Despite the majority of normal pregnant women reaching adequate levels of circulating thyroid hormones, in some cases, women with normal pregnancies have low level of free T4 during first ...
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