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Aune Dagfinn D From the aDepartment of Preventive Cardiology, Oslo University Hospital Ullevål, Oslo, Norway; bDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway; cDepartment of Epidemiology and Biostatistics, Imperial College, London, United Kingdom; dDepartment of Pediatric Research, Rikshospitalet, Oslo University Hospital, University of Oslo, Oslo, Norway; eSection of obstetrics, Division of Obstetrics and Gynaecology, Rikshospitalet, Oslo University Hospital, Oslo, Norway; and fDepartment of Health Promotion and Education, Loma Linda University, Loma Linda, - - 2014
Physical activity has been hypothesized to reduce the risk of preeclampsia, but epidemiologic studies have not shown consistent results. Therefore, we conducted a systematic review and dose-response meta-analysis of epidemiologic studies. PubMed, Embase, and Ovid databases were searched for case-control and cohort studies of physical activity and preeclampsia up to ...
Seckin Berna - - 2014
To investigate the effect of luteal phase support with vaginal progesterone on pregnancy rates of the gonadotropin-stimulated intrauterine insemination (IUI) cycles in patients with unexplained infertility with regard tofollicular growth. A total of 149 patients with unexplained infertility who underwent 166 recombinant follicle stimulated hormone--stimulated IUI cycles were prospectively randomized ...
Siristatidis Charalampos C Assisted Reproduction Unit, 3rd Department of Obstetrics and Gynecology, University of Athens, Rimini 1, Chaidari, 12642 Athens, Greece. Electronic address: - - 2014
In this report, we propose an intervention capable of improving IVF outcomes in subfertile women with poor ovarian response. This intervention derives from anecdotal data and observations in our daily practice, but most importantly from trials on experimental models and subfertile women with Polycystic Ovarian Syndrome (PCOS). Our hypothesis suggests ...
McDaniel Ian - - 2014
This article considers the objection to abortion that a woman who voluntarily engages in sexual activity is responsible for her fetus and so cannot have an abortion. The conclusion argued for is that the conceptions of responsibility that can ground the objection that are considered do not necessitate a requirement ...
Revelli Alberto A Physiopathology of Reproduction and IVF Unit, Department of Surgical Sciences, University of Torino, St. Anna Hospital, via Ventimiglia 3, 10126, Torino, Italy, - - 2014
This large prospective, randomized study was designed to compare the "mild" protocol with clomiphene citrate, low-dose gonadotropins and a GnRH-antagonist (CC/Gn/GnRH-ant protocol) with the "long" protocol with a GnRH-agonist and high-dose Gn for the controlled ovarian hyperstimulation (COH) of patients with expected poor ovarian responsiveness undergoing IVF. A total of ...
Chau Anthony A aDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston Massachusetts, USA bDepartment of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada cDepartment of Anesthesia, Faculty of Medicine, Harvard Medical School, Boston, Maassachusetts, - - 2014
In many labor and delivery units, the obstetric anesthesiologist is often responsible for managing and stabilizing the acutely septic parturient. The management of maternal sepsis has been summarized previously; this study will focus on the implications of maternal sepsis on the fetus, and ways to optimize fetal outcomes. Although the ...
Verdonk Koen K *Department of Internal Medicine, Division of Vascular Medicine and Pharmacology, Erasmus MC, Rotterdam, The - - 2014
Pregnancy demands major changes of the cardiovascular system, and this involves, among others, activation of the RAAS (renin-angiotensin-aldosterone system), allowing an aldosterone-dependent increase in volume. Remarkably, a relative resistance to the pressor response of AngII (angiotensin II) develops simultaneously to prevent the increase in blood pressure that would normally accompany ...
Proisy Maïa M 1 Department of Imaging, CHU de Rennes-Hôpital Sud, Rennes, - - 2014
OBJECTIVE. This article provides an overview of the typical appearance of biomechanical and physiologic changes in pregnancy and an update on related pathophysiology. Conditions occurring during the childbearing, delivery and postpartum periods will be reported separately. CONCLUSION. Pregnancy causes biomechanical and physiologic changes that may be responsible for a wide ...
Manikandan K K Department of Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, - - 2014
Frusemide use in pregnancy is generally restricted to patients with cardiac decompensation. In the past, maternal administration of oral frusemide had been tried to identify non-functioning fetal kidneys by utilizing the diuretic effect of frusemide on the fetal kidneys. We report a case of primigravida with severe mitral stenosis presenting ...
Mascarenhas Mariano M Reproductive Medicine Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, - - 2014
The overwhelming numbers of twins following assisted reproductive technology (ART) are dichorionic twins, but monochorionic twins account for around 0.9% of post ART pregnancies. The data for post ART-monochorionic pregnancy outcomes are scarce due to the rarity of this condition. Hence, we evaluated the obstetric outcomes of monochorionic and dichorionic ...
Saberi Farzaneh F Department of Midwifery, Kashan University of Medical Sciences, Kashan, IR - - 2014
Nausea and vomiting are common and unpleasant complications in pregnancy. Although many alternative therapists support the use of ginger for nausea and vomiting of pregnancy, there is currently insufficient clinical evidence to support its use in this condition. The present study was performed to assess the effectiveness of ginger in ...
Sunkara Sesh Kamal SK King's College London, London, - - 2014
Is there a relationship between ovarian reserve, quantified as ovarian response to stimulation, and miscarriage rate following IVF treatment? There is a strong association between the number of oocytes retrieved and miscarriage rate following IVF treatment, with the miscarriage rate decreasing with an increasing number of oocytes and then levelling ...
Trakakis Eftihios E Third Department of Obstetrics and Gynecology, University of Athens Medical School, Attikon General University Hospital , Athens , Greece - - 2014
Abstract We aim to present the first case of a pregnancy achieved by administering sildenafil (Viagra) to a woman not responding to controlled ovarian hyperstimulation (COH) with the sole use of gonadotropins. A 37-year-old woman underwent COH, as part of an intracytoplasmic sperm injection (ICSI) cycle, with the combination of ...
Kutlusoy Fatma F Department of Obstetrics & Gynecology, Gazi University School of Medicine , Ankara , Turkey - - 2014
Abstract In this study, our objective was to determine the effect of adding estradiol hemihydrate (E2) to progestin (P) for luteal phase support on pregnancy outcome in in vitro fertilization (IVF) cycles with poor response to gonadotropins. Ninety-five women with poor ovarian response who underwent controlled ovarian hyperstimulation (COH) with ...
Hochmeister Sonja S Medical University Graz, Department of Neurology, Graz, - - 2014
Neurofascin was recently reported as a target for axopathic autoantibodies in patients with multiple sclerosis (MS), a response that will exacerbate axonal pathology and disease severity in an animal model of multiple sclerosis. As transplacental transfer of maternal autoantibodies can permanently damage the developing nervous system we investigated whether intrauterine ...
Whitaker-Azmitia Patricia M PM Department of Psychology, Stony Brook University, Stony Brook, NY 11794, United States. Electronic address: - - 2014
Studies show increased autism risk among children born to mothers experiencing obstetrical complications. Although this is usually interpreted as suggesting that the obstetrical complications could be causing autism, it is possible that a single factor could be responsible for both complications and autism. We hypothesized that low levels of the ...
Schleger Franziska F a fMEG Center , University of Tübingen , Tübingen , - - 2014
Numerosity discrimination has been demonstrated in newborns, but not in fetuses. Fetal magnetoencephalography allows non-invasive investigation of neural responses in neonates and fetuses. During an oddball paradigm with auditory sequences differing in numerosity, evoked responses were recorded and mismatch responses were quantified as an indicator for auditory discrimination. Thirty pregnant ...
Guzmán-Gutiérrez Enrique E Group of Research and Innovation in Vascular Health, Facultad de Ciencias de la Salud, Universidad San Sebastian Concepción, Chile ; Facultad de Ciencias de la Salud, Universidad San Sebastián Concepción, - - 2014
Synthesis of thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3), in the human fetus starts from 17 to 19th weeks of gestation. Despite the majority of normal pregnant women reaching adequate levels of circulating thyroid hormones, in some cases, women with normal pregnancies have low level of free T4 during first ...
Myers Dean A DA Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73140, USA, - - 2014
The fetus has the extraordinary capacity to respond to stress during development, which, in a large part, is mediated by the hypothalamo- pituitary-adrenal (HPA) axis. Hypoxia represents a significant risk to fetal homeostasis and can occur in a wide range of settings including maternal smoking, preeclampsia, preterm labor and high ...
Hansen Thomas R TR Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, Colorado State University, 3197 Rampart Road, Fort Collins, CO, 80521, USA, - - 2014
Successful pregnancy includes remodeling and differentiation of the endometrium in response to sex steroid hormones, development of maternal immunotolerance to the implanting embryo, and modification of the local uterine environment by the embryo to suit its own needs. The major signal released by the ruminant conceptus during establishment of pregnancy ...
Yildirim Mehmet Erol ME Department of Urology, Turgut Ozal University, Faculty of Medicine, Ankara 06510, Turkey. - - 2014
Purpose: To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates. Materials and Methods: We examined the data ...
Hafeez Neveen A Abedel - - 2014
Preeclampsia is a multisystem disorder of unknown cause that is unique to human pregnancy affecting about 7-10% of pregnant women. CD4+CD25(bright) regulatory T (Treg) cells have been identified as a principle regulator of tolerance during pregnancy. The aim of this study was to demonstrate the change of peripheral CD4+CD25(bright) regulatory ...
Heidari-Bateni Giv G 0000-0001-5631-0399 Division of Pediatric Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO 63110, - - 2014
Objectives. To report the pharyngeal colonization rate of β-hemolytic streptococci and changes in the value of antistreptolysin O (ASO) and anti-DNase B serology titers during pregnancy. Methods. Healthy pregnant women were recruited and blood was drawn in each trimester. The upper limit of normal (ULN) values for ASO and anti-DNase ...
Zhu Li-Jun LJ Department of Gynecology and Obstetrics, The Fifth Hospital of Shanghai Affiliated to Fudan University Shanghai 200240, - - 2014
This study aimed to investigate changes in the expression levels of reactive oxygen species (ROS), superoxide dismutase (SOD), and hypoxia-inducible factor-1α (HIF-1α) in the trophoblasts of patients who had experienced missed abortions. The missed abortion group included 28 patients with missed abortions. The control group was comprised of 35 women ...
Zhang Shu S Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Jiangsu, - - 2014
In this study, we aimed to determine the provincial population-based seroprevalence in pregnant women and to further explore the association of maternal CMV infection status and adverse pregnancy/neonatal/growth outcomes in Jiangsu, China. In this case-control study, the sera from 527 pregnant women with adverse pregnancy/neonatal outcomes and 496 mothers of ...
Akpınar Funda F Department of In Vitro Fertilization, Etlik Zübeyde Hanım Maternity & Women's Health Teaching Research Hospital, Ankara, - - 2014
To determine if body mass index has an effect on the outcome of in vitro fertilization in patients with polycystic ovary syndrome undergoing controlled ovarian hyperstimulation. The study included 337 cycles. Patients were stratified into the following 3 groups: normal weight, overweight, and obese. The primary outcome measures were response ...
Yalçınkaya Ender E Eurofertil IVF Center, İstanbul, - - 2014
To compare the outcomes of embryos that were given a dynamic score based on a preconstructed embryo scoring model and to analyze whether this model complies with our data. A total of 910 transferred embryos with known implantation data were retrospectively analyzed in this study. All of the embryos were ...
Cuervo Marta M Department of Nutrition, Food Sciences and Physiology, Center for Nutritional Research, University of Navarra, Pamplona 31008, Spain. - - 2014
The nutritional status and lifestyle of women in preconception, pregnancy and lactation determine maternal, fetal and child health. The aim of this cross-sectional study was to evaluate dietary patterns and lifestyles according the perinatal physiological status in a large sample of Spanish women. Community pharmacists that were previously trained to ...
Huang Ying Y Department of Reproductive Center, Navy General Hospital, Fucheng Road, Beijing 100048, China ; Department of Obstetrics and Gynecology, Navy General Hospital, Fucheng Road, Beijing 100048, - - 2014
Background. Polycystic ovarian syndrome (PCOS) women undergoing in vitro fertilization and embryo transfer (IVF-ET) treatment always attain a low cumulative pregnancy rate disaccording with the satisfactory number of oocytes. Objective. We aim to evaluate the status of coagulation and fibrinolytic system in PCOS patients undergoing controlled ovarian hyperstimulation (COH) process. ...
Li Bo B Department of Obstetrics and Gynecology, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, - - 2014
Sperm morphology is the best predictor of fertilization potential, and the critical predictive information for supporting assisted reproductive methods selection. Given its important predictive value and the declining reality of semen quality in recent years, the threshold of normal sperm morphology rate (NSMR) is being constantly corrected and controversial, from ...
Hu Chunxiu C Department of Obstetrics & Gynecology, Affiliated Hospital of The Chinese People's Armed, Police Force Logistics College Tianjin, - - 2014
Evaluate the cause of infertility and impairment of tubal reproductive functions in infertility patients, who suffered tubal pregnancy after conservative treatment, using laparoscopy, hysteroscopic tubal catheterization, and hydrotubation. Seventy-five infertility patients treated for tubal pregnancies were divided into two groups based on past treatment methods of their tubal pregnancies, conservative-medical ...
Han Lei L Department of Obstetrics and Gynecology, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, P.R.China; Department of Obstetrics and Gynecology, the 306th Hospital of the Chinese People's Liberation Army, Beijing, - - 2014
Preeclampsia (PE) is an obstetric disorder with high morbidity and mortality rates but without clear pathogeny. The dysfunction of the blood coagulation-fibrinolysis system is a salient characteristic of PE that varies in severity, and necessitates different treatments. Therefore, it is necessary to find suitable predictors for the onset and severity ...
Palermo Gianpiero D GD The Ronald O. Perelman & Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, New York, New York, United States of - - 2014
Severely compromised spermatogenesis typical of men with virtual azoospermia or non-obstructive azoospermia requires an extreme search for spermatozoa. Our goal was to evaluate the usefulness of a meticulous search carried out in ejaculated or surgically retrieved specimens in achieving pre- and post-implantation embryo development. In a retrospective cohort study carried ...
Tarokhian Batoul B Acquired Immunodeficiency Research Center, Isfahan University of Medical Sciences, Isfahan, - - 2014
Some evidence has shown a relationship between primary human cytomegalovirus (CMV) infection and pregnancy loss. The impact of CMV infection reactivation during pregnancy on adverse pregnancy outcomes is not completely understood. It is proposed that altered immune response, and therefore, recurrence or reactivation of latent CMV infection may relate to ...
Kane Andrew - - 2013
Hypoxia is a common challenge to the fetus, promoting a physiological defence to redistribute blood flow towards the brain and away from peripheral circulations. During acute hypoxia, reactive oxygen species (ROS) interact with nitric oxide (NO) to provide an oxidant tone, which contributes to the mechanisms redistributing the fetal cardiac ...
Stampalija Tamara T Perinatology Research Branch, NICHD/NIH/DHHS , Bethesda, Maryland, and Detroit, Michigan , USA - - 2014
Intra-amniotic infection/inflammation (IAI) is causally linked with spontaneous preterm labor and delivery. The ST2L receptor and its soluble form (sST2) are capable of binding to interleukin (IL)-33, a member of the IL-1 superfamily. Members of this cytokine family have been implicated in the onset of spontaneous preterm labor in the ...
Kacerovsky Marian - - 2013
To determine the influence of microbial invasion of the amniotic cavity and acute histological chorioamnionitis on the intensity of the intraamniotic inflammatory response and neonatal morbidity in preterm prelabor rupture of membranes between 34 and 37 weeks. This study included 99 women with singleton pregnancies complicated by preterm prelabor rupture ...
Musilova Ivana - - 2013
Abstract Objective: To evaluate the intensity of the fetal inflammatory response, characterized by umbilical cord blood IL-6 levels, and neonatal outcome in the preterm prelabor rupture of membrane (PPROM) pregnancies using the pulsatile fetal splenic vein flow pattern. Methods: Women with singleton pregnancies complicated by PPROM at a gestational age ...
Boots Christina E CE University of Chicago, Chicago, Illinois; NorthShore University Health System, Chicago, - - 2013
To evaluate the effects of methotrexate (MTX) on the future fertility of women undergoing IVF by comparing ovarian reserve and ovarian responsiveness in the IVF cycle before and after an ectopic pregnancy (EP) treated with MTX. Retrospective cohort study. Private reproductive endocrinology and infertility practice. Sixty-six women undergoing IVF before ...
Rosenfeld Charles R - - 2013
The uteroplacental vasculature is refractory to α-adrenergic stimulation, and large conductance Ca(2+)-activated K(+) channels (BKCa) may contribute. We examined the effects of uterine artery (UA) BKCa inhibition with tetraethylammonium (TEA) on hemodynamic responses to phenylephrine (PE) at 101 to 117 days and 135 to 147 days of ovine gestation, obtaining ...
Golkari Ali A Department of Dental Public Health , - - 2013
Periodontal disease is considered as a risk factor for poor pregnancy outcomes, including preterm birth and low birth weight. Only few studies have assessed the knowledge and practice behaviours of healthcare providers, concerning oral health during pregnancy, periodontal diseases and their role in adverse pregnancy outcomes. The present study aimed ...
DiPietro Janet A JA Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: - - 2013
The bidirectional nature of mother-child interaction is widely acknowledged during infancy and childhood. Prevailing models during pregnancy focus on unidirectional influences exerted by the pregnant woman on the developing fetus. Prior work has indicated that the fetus also affects the pregnant woman. Our objective was to determine whether a maternal ...
Lee Joonho J Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, Detroit, MI, - - 2013
The human fetus is able to mount a systemic inflammatory response when exposed to microorganisms. This stereotypic response has been termed the 'fetal inflammatory response syndrome' (FIRS), defined as an elevation of fetal plasma interleukin-6 (IL-6). FIRS is frequently observed in patients whose preterm deliveries are associated with intra-amniotic infection, ...
Ghosh Sangita - - 2013
Intra-hepatic cholestasis of pregnancy is a cholestatic disorder characterized by i) pruritus, with onset in the third trimester of pregnancy, without any primary skin lesions, ii) elevated fasting serum bile acids > 10 μmol/L (and elevated serum transaminases), iii) spontaneous relief of signs and symptoms within two to three weeks ...
Voegtline Kristin M - - 2013
Knowledge about prenatal learning has been largely predicated on the observation that newborns appear to recognize the maternal voice. Few studies have examined the process underlying this phenomenon; that is, whether and how the fetus responds to maternal voice in situ. Fetal heart rate and motor activity were recorded at ...
Wyatt Stephanie N - - 2013
This is a qualitative descriptive study evaluating the maternal response after the woman has learned her pregnancy has a poor prognosis via telemedicine rather than in a traditional, face-to-face, consultation method. In general, telemedicine was positively viewed by the participants; however, the experience may be markedly improved by implementing several ...
Brown Stephen D - - 2013
BACKGROUND: To determine (1) whether fetal care paediatric (FCP) and maternal-fetal medicine (MFM) specialists harbour differing attitudes about pregnancy termination for congenital fetal conditions, their perceived responsibilities to pregnant women and fetuses, and the fetus as a patient and (2) whether self-perceived primary responsibilities to fetuses and women and views ...
Goodrich Kara K University of South Carolina, 921 Assembly St., Suite 318, Columbia, SC 29208, USA. - - 2013
African Americans and overweight or obese women are at increased risk for excessive gestational weight gain (GWG) and postpartum weight retention. Interventions are needed to promote healthy GWG in this population; however, research on exercise and nutritional barriers during pregnancy in African American women is limited. The objective of this ...
Hine Kristen - - 2013
Some have challenged Thomson's case of the famous unconscious violinist (UV) by arguing that in cases of consensual sex a woman is partially morally responsible for the existence of a needy fetus; since she is partially responsible she ought to assist the fetus, and so abortion is morally wrong. Call ...
Kahlo Kristina - - 2013
PROBLEM: The immune modulatory effect of heme oxygenase-1 (HO-1) is well documented in studies about sepsis and transplantation. This work evaluates the influence of HO-1 on the innate immune response during pregnancy. METHOD OF STUDY: Human first-trimester trophoblasts derived from normal pregnancies or spontaneous abortions were analyzed for their basal ...
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