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Scholl Theresa O - - 2008
In humans, the link between the maternal diet and the outcome of pregnancy is best illustrated by the classic study of wartime famine in Holland. During the famine it is likely that a low food intake reduced the glucose stream from the mother to fetus and gave rise to smaller ...
Schulze Kerry J KJ Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. - - 2008
Although hepcidin, a recently discovered peptide hormone, is considered a major regulator of iron metabolism and anemia in chronic inflammation, its role in anemia during pregnancy has not been characterized. Our objective was to characterize the role of hepcidin in anemia during pregnancy. We examined the relationships between urinary hepcidin, ...
Chen Jianmeng - - 2007
In this study, degradation of methyl tert-butyl ether (MTBE) by resting cells of Methylibium petroleiphilum PM1 was performed in poor nutrition solution, major component of which was MTBE. It was found that the biomass was hard to increase in poor nutrition, and the MTBE degradation activity was enhanced by 4.65-fold ...
Vazirinejad Reza - - 2007
BACKGROUND: Iron-deficiency anemia can have negative consequences for pregnant women. Previous investigations conducted to explore the association between iron-related components of mothers' serum and the outcome of pregnancy have had diverse results. OBJECTIVE: This study aimed to investigate the correlation between ferritin concentration (as the index of stored iron) of ...
Marahatta R - - 2007
Anaemia is the commonest problem in pregnancy in developing countries. It is defined by WHO as haemoglobin level less than 11 grams % in pregnancy. It is divided in to three degree mild degree (9.0-10.9 gm%), moderate degree (7.0-8.9 gm%) and severe degree(< 7.0 gm%). It carries a lot of ...
Mier-Cabrera Jennifer - - 2008
OBJECTIVE: To determine whether vitamins C and E supplementation lowers oxidative stress marker levels and improves pregnancy rate in women with endometriosis. METHODS: Thirty-four women with endometriosis received a bar containing vitamins C and E (343 mg and 84 mg, respectively) or placebo for 6 months. Plasma and peritoneal fluid ...
Ervasti Mari - - 2007
OBJECTIVES: Detection of iron deficiency during pregnancy with hemoglobin (Hb) and serum measurements is insignificant as the measurements may be affected by e.g. hemodilution or accelerated erythropoiesis. This study tests whether cell indices will give a more reliable measure of iron deficiency in pregnant women at term. METHODS: The population ...
Ziaei Saeideh - - 2008
OBJECTIVE: To measure levels of markers of anemia before and after delivery in women who had high hemoglobin levels during the early stage of the second trimester of pregnancy and did not receive iron supplementation during their pregnancies. METHODS: In a randomized, double-blind, placebo-controlled trial 244 women who had a ...
See Angela Wai-Man - - 2008
Vitamin A plays an essential role in vertebrate embryogenesis. In the present study, pregnant vitamin A-deficient (VAD) rats were maintained during early pregnancy on the short half-life vitamin A metabolite, all-trans retinoic acid (atRA), in an amount sufficient to support normal development to E10.5, with a higher level of atRA ...
Maret Wolfgang - - 2008
Risk of diseases of metabolism such as atherosclerosis and adult onset diabetes mellitus is increased by fetal malnutrition. Deficiencies of micronutrients essential for methylation are believed to contribute to the phenomenon in part through epigenetic abnormalities. Zinc is one of the nutrients essential for the epigenome. Because the worldwide prevalence ...
Silvestri Laura - - 2008
The liver peptide hepcidin regulates iron absorption and recycling. Hemojuvelin (HJV) has a key role in hepcidin regulation, and its inactivation causes severe iron overload both in humans and in mice. Membrane HJV (m-HJV) acts as a coreceptor for bone morphogenetic proteins (BMPs), whereas soluble HJV (s-HJV) may down-regulate hepcidin ...
Mavromatidis Georgios - - 2007
Factor XI (FXI) is a procoagulant factor and antifibrinolytic agent, and its absence causes a bleeding tendency. FXI deficiency is autosomal in inheritance, with severe FXI deficiency in homozygotes and partial deficiency in heterozygotes. A 24-year-old primigravida with an uneventful pregnancy and no history of bleeding manifestations was admitted to ...
Hoque, M; ;
Background An estimated 30% of the world's population is affected with anaemia. Anaemia in pregnancy is a leading cause of maternal and perinatal deaths in developing countries. In developing countries, anaemia affects almost two thirds of the pregnant population. It is also estimated that anaemia is responsible for as much ...
Kwak W S - - 2008
A study was conducted to determine the effect of broiler poultry litter (BL) supplementation to spent mushroom substrate (SMS) on its storage and feed-nutritional value improvement. In Exp. 1, the sawdust-based SMS from a king oyster mushroom (Pleurotus eryngii) farm was mixed with BL at 0%, 25%, 50%, 75% and ...
Vergne Sébastien - - 2008
Soya isoflavones, genistein and daidzein, are the focus of numerous studies investigating their potential effects on health and results remain controversial. Bioavailability is clearly a crucial factor influencing their bioefficacy and could explain these discrepancies. This study aimed at assessing: (1) the isoflavone content of sixty-nine European soya-derivative products sold ...
Donnelly Christopher T - - 2007
BACKGROUND: Carnitine deficiency is a potential cause of metabolic crisis during periods of high energy demand or stress. Affected individuals have very low carnitine levels in blood, decreased carnitine transport in fibroblasts, and commonly have mutations in the OCTN2 gene. CASE: We report management through pregnancy and delivery of a ...
Gouado I - - 2007
BACKGROUND: Vitamin A deficiency is a public health problem in Cameroon. Data on the bioavailability of carotenoid in fruits currently consumed in Cameroon are scarce. OBJECTIVE: To assess the systemic levels of carotenoids from mangoes and papaya consumed as juice, fresh or dried slices. METHODS: Two groups of seven healthy ...
Frankenburg Frances Rachel - - 2007
OBJECTIVE: Physicians often check folate and cobalamin levels in patients with schizophrenia and depression. The reasons for this practice are reviewed, as well as implications for treatment. METHOD: The physiology of the one-carbon cycle, involving folate, cobalamin, homocysteine, S-adenosyl-methionine, and methylene tetrahydrofolate reductase (MTHFR) is first reviewed, and then the ...
Dewey Kathryn G - - 2007
This review addresses the question of whether a short birth interval is associated with adverse nutritional outcomes for the mother or the child. Indices of anthropometric status (maternal weight or body mass index; child growth) and micronutrient status (e.g. iron or vitamin A) were included as outcomes. A computerized search ...
Wahed F - - 2007
A cross sectional descriptive type of study was done in 98 women of reproductive age. Among them 25 were in control group of non pregnant women and 73 were pregnant women of 1st, 2nd and 3rd trimester of pregnancy with and without iron supplementation. The period of study was July ...
Zimmermann Michael B - - 2007
CONTEXT: Pregnant women are often iron deficient, and iron deficiency has adverse effects on thyroid metabolism. Impaired maternal thyroid function during pregnancy may cause neurodevelopmental delays in the offspring. OBJECTIVE: Our objective was to investigate whether maternal iron status is a determinant of TSH and/or total T(4) (TT4) concentrations during ...
Luiking Yvette C - - 2007
Arginine supplementation is used in several disease states. In arginine-deficient states, supplementation is a logical choice of therapy. However, the definition of an arginine-deficient state is complex. For example, plasma arginine levels could be within normal range but intracellular arginine levels could be reduced because of membrane transport problems. Lysine ...
Ziaei S - - 2007
OBJECTIVE: To study the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin (Hb) > or = 13.2 g/dl. DESIGN: A randomised, double-blind, placebo-controlled trial. SETTING: Routine health services. POPULATION: Seven hundred and twenty-seven pregnant women with Hb > or = 13.2 g/dl in the early stage ...
Aboujaoude Ramzi - - 2007
BACKGROUND: Pregnancy has been associated with aplastic anemia, but a causal relationship has been questioned. CASE: A case of aplastic anemia was diagnosed during pregnancy and initially mimicked immune-mediated thrombocytopenic purpura. CONCLUSION: Pregnant women with aplastic anemia are at high risk. The severity of the disease and choice of the ...
Forster Della A - - 2009
OBJECTIVE: to explore the use of folic acid and other vitamin supplements before and during pregnancy, including type, dosage and form; who recommended supplement use and for what reason; and women's understanding of why they took folic acid. DESIGN: cross-sectional survey. SETTING: a public tertiary referral hospital in Melbourne, Australia. ...
Krauss-Etschmann Susanne - - 2007
BACKGROUND: Pregnant women usually meet their increased energy needs but do not always meet their increased micronutrient requirements. The supply of both folic acid and docosahexaenoic acid (DHA) has been related to positive pregnancy and infant outcomes. OBJECTIVE: We aimed to assess whether fish-oil (FO) supplementation with or without folate ...
Tunç Tu─čba - - 2007
The occurrence of restless legs syndrome in pregnancy is well known. However, the mechanism of this association is unclear. In this study, we aimed to identify the factors that predispose women to have restless legs syndrome during pregnancy. A total of 146 pregnant women were included in the study. Patients ...
Tamura Tsunenobu - - 2007
BACKGROUND: We report that inadequate vitamin B-6 status of Filipino mothers, assessed by erythrocyte aspartate aminotransferase activity coefficient (EAST-AC), is associated with an increased risk for isolated cleft lip with or without cleft palate (CL/P) in their children. Its association with the status assessed by plasma pyridoxal-5'-phosphate (PLP) concentrations is ...
Rioux France M - - 2007
Iron-deficiency anemia is still prevalent among pregnant women living in industrialized countries such as Canada. To prevent this deficiency, iron supplements (30 mg/d) are routinely prescribed to Canadian pregnant women. Recently, dietary reference intakes for iron have increased from 18 and 23 mg/d during the second and third trimesters, respectively, ...
Schüz Joachim - - 2007
The young age at onset of many cancers in childhood has led to investigations on maternal exposures during pregnancy. Data from a population-based case-control study in Germany (1992-1997) that included 1,867 cases and 2,057 controls was used to investigate this question. Maternal use of vitamin, folate or iron supplementation was ...
Metzgeroth Georgia - - 2007
Zinc protoporphyrin (ZPP) is produced instead of heme as soon as iron support to erythropoiesis becomes insufficient. In iron deficiency the intra-erythrocytic ZPP concentration is increased. The aim of this study was to investigate whether ZPP is influenced by increased iron levels in hereditary hemochromatosis (HE) and is useful in ...
Forges Thierry - - 2007
Folates belong to the vitamin B group and are involved in a large number of biochemical processes, particularly in the metabolism of homocysteine. Dietary or genetically determined folate deficiency leads to mild hyperhomocysteinemia, which has been associated with various pathologies. Molecular mechanisms of homocysteine-induced cellular dysfunction include increased inflammatory cytokine ...
Andersen Henriette S HS Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, - - 2007
Cu and Fe metabolism are known to be linked, but the interactions during pregnancy are less well studied. In the present study we used rats to examine the effect of Cu deficiency during pregnancy on Fe and Cu levels in maternal and fetal tissue and on the gene expression profile ...
Judge Michelle P - - 2007
Within the visual system, docosahexaenoic acid (DHA, 22:6n-3) is an important structural component for retinal photoreceptors and cortical gray matter. There is a marked decrease in neural DHA accumulation in the face of DHA deficiency. DHA is accumulated at an accelerated rate during pregnancy, especially in the third trimester. However, ...
Pérez-López Faustino R - - 2007
Vitamin D is a secosteroid with an endocrine mechanism of action which is sequentially synthesized in humans in the skin, liver and kidneys. The active hormone, 1alpha,25-dihydrocholecalciferol [1,25(OH)2D3], is often considered only in terms of its role in controlling calcium and phosphorus homeostasis. However, cumulative evidence points to the presence ...
Mukhopadhyay Asima - - 2007
In a prospective study of 40 women, mean corpuscular volume (MCV) values in second and third trimesters were compared between women who were iron deficient and those who were iron replete. There was no difference in the two groups. Hence reduced MCV seen in iron deficiency anaemia cannot be relied ...
Eby George A - - 2007
Primary dysmenorrhea, menstrual cramps in otherwise well women, produces mild to debilitating cramping of the uterus. More than half, and by some estimates 90% of all American women experience menstrual cramps during the first several days of menstruation. About one in ten women are unable to perform their normal routine ...
Kearney Susan L - - 2007
Hepcidin, a regulator for iron homeostasis, is induced by inflammation and iron burden and suppressed by anemia and hypoxia. This study was conducted to determine the hepcidin levels in patients with congenital chronic anemias. Forty-nine subjects with anemia, varying degrees of erythropoiesis and iron burden were recruited. Eight children with ...
Parbs Anika - - 2007
The effect of different concentrations of total inorganic carbon (TIC) and flow rates on the reactivity of iron metal with trichloroethylene (TCE) was studied in column experiments to verify whether concentration or mass flux of TIC is the major key parameter for barrier performance. First-order rate coefficients (kobs) for TCE ...
Harvey Linda J - - 2007
BACKGROUND: Women have an increased risk of iron deficiency during pregnancy because of the demands of the developing fetus. Iron supplements are commonly advocated as a prophylactic treatment and are generally taken with meals to reduce side effects, but iron can interfere with the absorption of zinc. OBJECTIVE: The aim ...
Maghbooli Zhila - - 2007
BACKGROUND: Adequate vitamin D concentrations during pregnancy are necessary to neonatal calcium homeostasis, bone maturation and mineralization. The aim of study is to evaluate serum vitamin D concentrations in mothers and their newborns and effect of vitamin D deficiency on pregnancy outcomes. METHODS: 552 pregnant women were recruited from Tehran ...
Hösli Irene - - 2007
There is a rising interest in a balanced and varied women's diet not only preconceptionally but also during pregnancy and in the breastfeeding period in order to reduce fetal, neonatal, and maternal risks. A decreased intake of omega 3-fatty acids (FA) or deficiencies of micronutrients are a global health problem, ...
Tjeertes I F A - - 2007
After admitting a patient to our Neonatal Intensive Care with a severe anemia and an ear malformation, we ruled out any other cause than maternal medication use. Knowing she used mycophenolate mofetil during pregnancy, we looked for related articles. Two articles were found describing ear malformations, but no article was ...
Dim Cyril C - - 2007
More than half of the pregnant women in the world have hemoglobin levels indicative of anemia. Knowledge of the current situation of the condition in our environment is necessary. This knowledge will motivate antenatal caregivers toward early detection and prompt management of anemia in pregnancy. Our aim was to determine ...
Camadoo Laxmi - - 2007
Maternal vitamin D insufficiency is not uncommon. Infants born to mothers who are deficient in vitamin D and or calcium, usually due to cultural modifications in their diets or clothing habits, and in addition are breastfed, are at risk of developing vitamin D deficiency and hypocalcaemia. We present a case ...
Reveiz L - - 2007
Iron deficiency, the most common cause of anaemia in pregnancy worldwide, can be mild, moderate or severe. Severe anaemia can have very serious consequences for mothers and babies, but there is controversy about whether treating mild or moderate anaemia provides more benefit than harm. To assess the effects of different ...
Cotter Paul E - - 2006
Restless legs syndrome (RLS) is a common condition that is frequently unrecognized, misdiagnosed and poorly managed. It is characterized by uncomfortable sensations deep in the legs developing at rest that compel the person to move; symptoms are worst at night and sleep disturbance is common. RLS occurs in 7%-11% of ...
Glenville Marilyn - - 2006
PURPOSE OF REVIEW: This review examines whether nutritional supplements during pregnancy have a role to play in the health of the mother, outcome of pregnancy or health of the baby. It will put into context the increased use of nutritional supplements in pregnancy and whether there is an evidence base ...
Dungarwalla M - - 2007
We describe 11 patients with severe refractory autoimmune cytopenias treated with the anti-CD20 monoclonal antibody rituximab. Six patients had autoimmune neutropenia (AIN), two had pure red cell aplasia (PRCA), one had AIN and autoimmune haemolytic anaemia, one had AIN and immune thrombocytopaenia purpura (ITP) and one had PRCA and ITP. ...
Czeizel Andrew E - - 2006
Two previous Hungarian intervention trials showed that periconceptional folic acid-containing multivitamin supplementation did not change the total (birth + fetal) prevalence of cases with multiple congenital abnormalities (MCAs). However, two US observational studies found an elevated risk for MCAs in the offspring of women who reported periconceptional use of multivitamins ...
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