Search Results
Results 51 - 100 of 1293
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Riggin Lauren - - 2013
Fluoxetine is the selective serotonin reuptake inhibitor (SSRI) with the longest clinical use. Published reports regarding its fetal safety are contradictory. We aimed to establish the fetal safety of the drug. We performed a systematic review of the literature, searching PubMed, Medline, and Embase from inception to August 31, 2012, ...
Groeneveld E - - 2013
STUDY QUESTION: Does preconceptionally started low-dose aspirin prevent hypertensive pregnancy complications and preterm delivery in IVF patients? SUMMARY ANSWER: The current data do not support the use of preconceptionally started low-dose aspirin treatment for the prevention of hypertensive pregnancy complications and preterm delivery in IVF women. WHAT IS KNOWN ALREADY: ...
Lashley Eileen E L O - - 2013
PROBLEM: During pregnancy, antibodies are induced that target the paternal human leukocyte antigens of the semi-allogeneic fetus. The level and presence of these antibodies have been reported increased as well as decreased for a variety of pregnancy complications; the clinical relevance and consequences of these antibodies are not very clear. ...
Gil Monica - - 2013
PURPOSE: To determine whether the use of Magnetic Activated Cell Sorting (MACS) as a sperm selection technique improves ART success rates in couples undergoing assisted reproduction treatment. METHODS: Systematic review and meta-analysis of prospective randomized trials. Two reviewers conducted study selection and data extraction independently. RESULTS: Five studies (prospective randomized ...
Sun Xiaoli - - 2013
PURPOSE: To evaluate the effect of MET on ovulation and reproductive outcomes in patients with polycystic ovary syndrome. METHODS: Meta-analysis of available data from randomized controlled trials that examined the ovulation, pregnancy and live birth rate after the administration of clomiphene citrate (CC) or MET alone or combined. RESULTS: The ...
Reif Philipp - - 2013
OBJECTIVE: To evaluate the efficacy of misoprostol in the treatment of missed or incomplete abortion in relation to uterine position. METHODS: In a retrospective cohort study, misoprostol was evaluated as first-line treatment for missed and incomplete abortion before 13 gestational weeks. Between 2009 and 2011, women received 600μg of sublingual ...
Nair Rohini R - - 2013
OBJECTIVE: To study the genetic association between methylenetetrahydrofolate reductase (MTHFR) A1298 polymorphism and recurrent pregnancy loss (RPL). DESIGN: Prospective case-control study, systematic review, and meta-analysis using an electronic database up to July 27, 2012. SETTING: Meta-analysis of four studies on RPL and three studies on spontaneously aborted embryos, including the present ...
Phillips James A S - - 2013
We performed a systematic review and meta-analysis to examine whether a difficult embryo transfer or the presence of blood on the transfer catheter affects assisted reproduction outcomes. We searched the following databases: Cochrane Central Register of Controlled Trials (CENTRAL), Database of Abstracts of Reviews of Effects (DARE), MEDLINE, Embase, PsycINFO, ...
Rupasinghe Madhumani - - 2013
We read Romualdi et al's recent systematic review and meta-analysis of anticoagulant therapy for venous thromboembolism (VTE) during pregnancy (1) with great interest. They conclude that anticoagulant therapy (primarily low molecular weight heparin [LMWH] in > 80% of cases) is safe and effective with a low incidence of antenatal (1.41% ...
Velkeniers B - - 2013
BACKGROUNDPrevious meta-analyses of observational data indicate that pregnant women with subclinical hypothyroidism have an increased risk of adverse pregnancy outcome. Potential benefits of levothyroxine (LT4) supplementation remain unclear, and no systematic review or meta-analysis of trial findings is available in a setting of assisted reproduction technologies (ART).METHODSRelevant trials published until ...
Gomez Gabriela B - - 2013
To perform a systematic review and meta-analysis of reported estimates of adverse pregnancy outcomes among untreated women with syphilis and women without syphilis. PubMed, EMBASE and Cochrane Libraries were searched for literature assessing adverse pregnancy outcomes among untreated women with seroreactivity for infection and non-seroreactive women. Adverse pregnancy outcomes were ...
Nieuwenhuijsen Mark J - - 2013
ABSTRACT: BACKGROUND: Various epidemiological studies have suggested associations between environmental exposures and pregnancy outcomes. Some studies have tempted to combine information from various epidemiological studies using meta-analysis. We aimed to describe the methodologies used in these recent meta-analyses of environmental exposures and pregnancy outcomes. Furthermore, we aimed to report their ...
Wei Shu-Qin - - 2013
Abstract OBJECTIVE: To estimate the associations between maternal vitamin D status and adverse pregnancy outcomes. STUDY DESIGN: We searched electronic databases of the human literature in PubMed, EMBASE and the Cochrane Library up to October, 2012 using the following keywords: 'vitamin D' and 'status' or 'deficiency' or 'insufficiency' and 'pregnancy'. ...
Blumfield Michelle L - - 2013
Micronutrient status during pregnancy influences maternal and fetal health, birth outcomes, and the risk of chronic disease in offspring. Research reporting dietary intake during pregnancy in nationally representative population samples, however, is limited. This review summarizes the micronutrient intakes of pregnant women from developed countries and compares them with relevant ...
Hutson J R - - 2013
Maintaining remission of inflammatory bowel disease (IBD) during pregnancy is critical for positive pregnancy outcomes. Conflicting data exist regarding the association between thiopurine use for IBD treatment in pregnancy and adverse pregnancy outcomes and this meta-analysis aims to clarify this association. A meta-analysis was performed of all original human studies ...
Hawkes Sarah J - - 2013
Despite an increase in the proportion of women who access antenatal care, mother-to-child transmission of syphilis continues to be a consequence of undiagnosed, untreated, or inadequately treated maternal syphilis. We reviewed evidence on the optimal timing of antenatal interventions to prevent mother-to-child transmission of syphilis and its associated adverse outcomes. ...
Yu Zhangbin - - 2013
Overweight/obesity in women of childbearing age is a serious public-health problem. In China, the incidence of maternal overweight/obesity has been increasing. However, there is not a meta-analysis to determine if pre-pregnancy body mass index (BMI) is related to infant birth weight (BW) and offspring overweight/obesity. Three electronic bibliographic databases (MEDLINE, ...
Einarson Thomas R - - 2013
BackgroundNausea and vomiting of pregnancy (NVP) is the most common medical condition during gestation, carrying tremendous health burden, especially for the severe form, hyperemesis gravidarum (HG). The rates of NVP in the USA have not been systematically calculated.ObjectivesTo estimate the rates of NVP and HG in the USA. MethodsA meta-analysis was ...
Einarson Thomas R - - 2013
BackgroundNausea and vomiting of pregnancy (NVP) is the most common medical condition in pregnancy, affecting women worldwide. It is unclear whether its prevalence and severity NVP are variable across different nations and races.PurposeTo summarize global rates of NVP as reported in the literature using meta-analysis. MethodsWe searched Medline, Embase and Cochrane ...
Sukrat Bunyarit - - 2013
Objective. To conduct a systematic review and meta-analysis of hemoglobin effect on the pregnancy outcomes. Methods. We searched MEDLINE and SCOPUS from January 1, 1990 to April 10, 2011. Observational studies addressing association between hemoglobin and adverse pregnancy outcomes were selected. Two reviewers independently extracted data. A mixed logistic regression ...
Valle Rafael F RF Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611-5715, USA. - - 2013
The introduction of hysteroscopy to diagnose and treat intrauterine conditions, specifically to divide the uterine septum, or metroplasty, has replaced the traditional laparotomy approach, and objective results demonstrate its salutary effects in women treated. Hysteroscopic metroplasty averts the implications of major invasive abdominal surgery, with good and satisfactory results in ...
Zagouri Flora - - 2012
Landmark studies have established trastuzumab in the treatment of HER2-positive breast cancer. The present systematic review and meta-analysis aims to synthesize all available data, so as to evaluate the safety of trastuzumab during pregnancy. This study was performed in accordance with the PRISMA guidelines. All studies that examined the safety ...
Molina-Solana R - - 2012
The aim of this study was to investigate the effect of environmental factors, such as tobacco, alcohol and folic acid intake, obesity, stressful events, low blood levels of zinc and fever during pregnancy, on the incidence of cleft lip and/or palate (CL±P). An electronic search was performed in the Cochrane ...
Salmelin Anette - - 2012
Background. Computerized ST analysis of fetal electrocardiography (ECG) combined with cardiotochography (CTG) has been introduced for intrapartum monitoring and is the prevailing method when ST analysis (STAN®) is used. Objective. To assess the evidence that computerized ST analysis during labor reduces the incidence of fetal metabolic acidosis, hypoxic ischemic encephalopathy, ...
Romualdi E - - 2012
Venous thromboembolism (VTE) is one of the most relevant causes of maternal death in industrialized countries. Low molecular weight heparin (LMWH), continued throughout the entire pregnancy and puerperium, is currently the preferred treatment for patients with acute VTE occurred during pregnancy. However, evidences on the efficacy and safety of anticoagulant ...
Hermes Wietske - - 2012
The objective of this study was to perform a systematic review and meta-analysis of studies assessing biochemical cardiovascular risk factors in women with previous hypertensive pregnancy disorders and women with previous normotensive pregnancies. Data were collected from PubMed and EMBASE (from inception to February 28, 2011) supplemented by manual searches ...
Orvieto Raoul - - 2012
The availability of gonadotrophin-releasing hormone (GnRH) antagonists for ovarian stimulation protocols has generated many meta-analyses comparing it to GnRH agonist long protocols. These meta-analyses have yielded conflicting results for pregnancy rate, with a tendency toward a better outcome for GnRH agonists. Recently, a Cochrane review seems to have settled the ...
Roque Matheus - - 2012
OBJECTIVE: To examine the available evidence to assess if cryopreservation of all embryos and subsequent frozen embryo transfer (FET) results in better outcomes compared with fresh transfer. DESIGN: Systematic review and meta-analysis. SETTING: Centers for reproductive care. PATIENT(S): Infertility patient(s). INTERVENTION(S): An exhaustive electronic literature search in MEDLINE, EMBASE, and ...
Wilasrusmee C - - 2012
Laparoscopic appendicectomy has gained wide acceptance as an alternative to open appendicectomy during pregnancy. However, data regarding the safety and optimal surgical approach to appendicitis in pregnancy are still controversial. This was a systematic review and meta-analysis of studies comparing laparoscopic and open appendicectomy in pregnancy identified using PubMed and ...
Salmelin Anette - - 2012
Background: Computerised ST analysis of fetal electrocardiography (ECG) combined with cardiotochography (CTG) has been introduced for intrapartum monitoring and is the prevailing method when ST analysis (STAN®) is used. Objectives: To assess the evidence that computerised ST analysis during labor reduces the incidence of fetal metabolic acidosis, hypoxic ischemic encephalopathy, ...
Seshadri S - - 2012
The effect of heparin on IVF outcome has been widely debated in the literature. A systematic review and meta-analysis of the published literature was conducted to evaluate the effect of heparin treatment on IVF outcome. Searches were conducted on MEDLINE, EMBASE, Cochrane Library and Web of Science and identified 10 ...
Dasanayake Ananda P - - 2012
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: A meta-analysis of randomized controlled trials shows no evidence that periodontal treatment during pregnancy prevents adverse pregnancy outcomes. Baccaglini L. J Am Dent Assoc 2011;142(10):1192-3. REVIEWER: Ananda P. Dasanayake, BDS, MPH, PhD, FACE PURPOSE/QUESTION: To determine whether scaling and root planning performed on pregnant women ...
de Barros Pinheiro Melina - - 2012
Preeclampsia is a multifactorial disease characterized by high blood pressure and proteinuria after the 20th week of pregnancy. Preeclampsia is associated with microvasculature fibrin deposition and maternal organ dysfunction. D-dimer (D-Di) has been used as a marker of production/degradation of fibrin in vivo. D-Di has emerged as a useful diagnostic ...
Seol H J - - 2012
Abdominal pregnancy is extremely rare and can result from the reimplantation of an intrauterine pregnancy after spontaneous uterine rupture. In this report, we present the case of a secondary missed abdominal pregnancy resulting from iatrogenic uterine perforation during dilatation and curettage in an early intrauterine pregnancy and subsequently misdiagnosed as ...
Fekete Katalin - - 2012
The beneficial effect of folic acid supplementation before and shortly after conception is well recognized, whereas the effect of supplementation during the second and third trimesters is controversial and poorly documented. Our aims were to systematically review randomized controlled trials (RCTs) investigating the effect of folate supplementation on birth weight, ...
Wahabi Hayfaa A - - 2012
Pre-gestational diabetes mellitus is associated with increased risk for maternal and fetal adverse outcomes. This systematic review was carried out to evaluate the effectiveness and safety of pre-pregnancy care in improving the rate of congenital malformations and perinatal mortality for women with pre-gestational diabetes mellitus. We searched the following databases, ...
Nikfar Shekoufeh - - 2012
Selective serotonin reuptake inhibitors (SSRIs) are the most frequently used antidepressants during pregnancy. There are conflicting results about their influence on pregnancy outcomes. The goal of this study was to update our previous meta-analysis about pregnancy outcomes following exposure to SSRIs. For this purpose, all relevant databases were searched from ...
Wright Caroline F CF PHG Foundation, 2 Worts Causeway, Cambridge, - - 2012
Cell-free fetal DNA (cffDNA) can be detected in maternal blood during pregnancy, opening the possibility of early non-invasive prenatal diagnosis for a variety of genetic conditions. Since 1997, many studies have examined the accuracy of prenatal fetal sex determination using cffDNA, particularly for pregnancies at risk of an X-linked condition. ...
Klimentopoulou Alexandra - - 2012
Maternal smoking during pregnancy has been often implicated in the development of childhood leukemia with ambiguous results. Hence, we conducted a meta-analysis aiming to summarize current evidence and quantify any tentative impact. We retrieved one cohort (553 leukemias compared to 1,440,542 children), 20 case-control studies and also analyzed the updated ...
Gorog Krisztian - - 2011
Childhood obesity is a worldwide public health concern. Recent studies from high income countries have demonstrated associations between maternal smoking during pregnancy and children's excess body weight. We examine associations between maternal smoking during pregnancy and children's overweight or obesity, in six countries in the less affluent Central/Eastern European region. ...
Eskander Ramez N - - 2011
Leukemia during pregnancy is rare, posing a complex series of questions, including appropriate therapy and maternal counseling. Management of chronic myelocytic leukemia (CML) during pregnancy is limited. Our patient presented at 30 weeks' gestation with anemia, leukocytosis, and a non-productive cough. Polymerase chain reaction performed on a peripheral blood sample confirmed ...
Martin Jovita - - 2011
The concomitant occurrence of pregnancy and chronic myelogenous leukemia is uncommon. We describe the successful management of a 24-year-old woman in the first trimester of her pregnancy with chronic myelogenous leukemia (CML) in the chronic phase, who was on treatment with imatinib, which was stopped by 10(th) week of pregnancy. ...
Scarlata Candace D - - 2011
In 2001, the sudden collapse of the Columbia Basin population of pygmy rabbits prompted the initiation of a captive breeding program to facilitate reintroduction, but reproductive success in captivity has not met expectations. Therefore, the objective of this study was to characterize the reproductive and adrenal endocrinology of this endangered ...
Albiger N M - - 2011
Objective The mechanisms inducing steroidogenesis in primary aldosteronism (PA) remain poorly defined. It was recently demonstrated that some G-protein-coupled receptors are abnormally expressed in aldosterone-producing adenomas (APA). We evaluated the potential role of LH and GNRH receptors (LHR (or LHCGR) and GNRHR) in regulating aldosterone secretion in a patient with ...
Bednarek-Tupikowska Gra┼╝yna - - 2011
Cushing's syndrome (also known as hypercortisolemia) is rare in pregnant women due to the menstrual disturbances and infertility in women with hypercortisolism. A diagnosis of pathological hypercortisolism in pregnant women is often difficult as some symptoms of the disease may be associated with a complicated pregnancy. Hypercortisolemia leads to serious ...
Farage Miranda A - - 2011
The morphology and physiology of both the vulva and vagina undergo characteristic age-related changes over a lifetime. At birth, these tissues exhibit the effects of residual maternal estrogens. During puberty, the vulva and vagina mature under the influence of adrenal and gonadal steroid hormones. During the reproductive years, the vagina ...
Hiroshima Yuki - - 2011
A 31-year-old pregnant woman was diagnosed with chronic-phase chronic myeloid leukemia at gestational week 16. To avoid exposure of the fetus to teratogenic agents, the patient opted for a course of careful observation only for the duration of her pregnancy. We detected 9.1% of BCR-ABL-positive cells in the patient's colostrum ...
Espy Kimberly Andrews - - 2011
Smoking during pregnancy is a persistent public health problem that has been linked to later adverse outcomes. The neonatal period--the first month of life--carries substantial developmental change in regulatory skills and is the period when tobacco metabolites are cleared physiologically. Studies to date mostly have used cross-sectional designs that limit ...
Karaman Kerem - - 2011
Adrenal cysts are rare and are usually discovered incidentally during diagnostic imaging, surgery, or autopsy. Most cystic lesions of the adrenal gland are nonfunctioning and become symptomatic when complicated by rupture, hemorrhage, or infection. A 40-year-old woman presented with a history of gradual-onset pain in her left flank region at ...
Choi Won Jun - - 2011
Cushing's syndrome (CS) in pregnancy may be confused with a complication of pregnancy, such as pre-eclampsia or gestational diabetes. We managed a case of CS in pregnancy that was considered to be severe pre-eclampsia due to uncontrolled hypertension. The fetus was delivered via emergency cesarean section at 31 weeks' gestation ...
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