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Garg Salil S Command Hospital, Lucknow, India (S.G.); Department of Medicine, Armed Forces Medical College, Pune, India (P.S., V.B.); Department of Cardiology, Ulster Hospital, Belfast, Northern Ireland (D.S.); Ruby Hall Clinic, Grant Medical Foundation, Pune, India (M.D.); and Department of Cardiology, Artemis Health Institute, Gurgaon, India - - 2014
To assess fetal cardiac structure and function and to evaluate the efficacy of routine fetal echocardiography for detection of fetal cardiac abnormalities in women with normal pregnancies and those with gestational diabetes mellitus. In this prospective study, we studied fetal cardiac structure and function in 294 uncomplicated singleton pregnancies and ...
Clur Sally-Ann B SA Department of Pediatric Cardiology of the Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands; The Centre for Congenital Heart Anomalies Amsterdam-Leiden (CAHAL), The - - 2014
Congenital heart defects(CHDs), the most commonly occurring congenital malformations, cause significant mortality and morbidity. With the recognition of early markers for CHD and the development of better ultrasound resolution, interest has turned towards performing a screening anomaly scan, including the heart, together with the nuchal scan. It is also possible, ...
Thathan Nopamas - - 2014
All sonomarkers used to screen for fetal hemoglobin (Hb) Bart's disease need high expertise, preventing them from being widely used. Fetal cardiac diameter to biparietal diameter (C/B) ratio is a simple marker which has never been evaluated for its effectiveness. Therefore, we conducted this study to evaluate the effectiveness of ...
Oztunc Funda F Istanbul University, Cerrahpasa Medical Faculty, Department of Pediatrics, Cardiology Unit, Istanbul, - - 2014
Abstract Objective: To evaluate the incidence, associated cardiac and extracardiac malformations and clinical outcome of fetuses with dextrocardia. Method: A retrospective review of 3,556 fetal echocardiograms between 2000 and 2011 revealed 39 cases of dextrocardia. Dextrocardia was defined as right-sided positioning of the fetal heart. Prenatal and postnatal records of ...
Barreto Enoch Quinderé de Sá EQ Department of Obstetrics, Paulista School of Medicine - Federal University of São Paulo (EPM-UNIFESP), São Paulo-SP, - - 2014
Abstract Objective: To describe a new technique for assessing fetal growth using three-dimensional ultrasonography (3DUS) using the extended imaging virtual organ computer-aided analysis (XI VOCAL) software and its respective reference curves. Methods: We conducted a cross-sectional study on 303 normal singleton pregnancies between their 20th and 34th weeks. To assess ...
Gati Sabiha S St. George's, University of London, London & University Hospital Lewisham, London, United - - 2014
-Patients with heart failure and chronic anemia frequently demonstrate left ventricular (LV) trabeculations which may be compatible with the diagnosis of left ventricular non-compaction (LVNC). We utilized the pregnancy model, which is characterized by reversible increase in cardiac preload and other changes in cardiac function, to assess the development of ...
McNamara H H Tom Bryson Department of Anaesthesia, Liverpool Women's Hospital, Liverpool, UK - - 2014
Cardiac output (CO) monitoring is helpful in the assessment of critically ill pregnant women, but invasive monitors are often unsuitable for use. We aimed to measure agreement between the non-invasive ultrasound cardiac output monitor (USCOM) and three-dimensional transthoracic echocardiography (3D-TTE) in pregnant women. Healthy pregnant women from 25 weeks gestation ...
Redondo-Angulo I I University of Barcelona, School of Biology, Biochemistry and Molecular Biology Dept., Barcelona, - - 2014
Pregnancy is a physiological model of adaptive and reversible heart enlargement. The molecular mechanisms determining physiological, non-pathological, heart enlargement are poorly known. Here we analyzed the role of the transcription factor C/EBPβ in the development of pregnancy-induced cardiac hypertrophy. We used a model of C/EBPβ haploinsufficiency (C/EBPβ+/-) in mice to ...
Pessel Cara C Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W. 168th St, PH-16, New York, NY 10032.. Electronic address: - - 2014
Maternal cardiac disease is a major cause of non-obstetric morbidity and accounts for 10-25% of maternal mortality. Valvular heart disease may result from congenital abnormalities or acquired lesions, some of which may involve more than one valve. Maternal and fetal risks in pregnant patients with valve disease vary according to ...
Simpson Lynn L LL Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th St, PH-16, New York, New York. Electronic address: - - 2014
Heart disease complicates 1-2% of pregnancies, and in preparation for pregnancy, these women should receive comprehensive preconception counseling. Risks to the mother and potential risks to the offspring secondary to the type and severity of maternal cardiac disease, its inheritance pattern, required medical therapy, and palliative or corrective procedures that ...
Levron Jacob J Department of Obstetrics & Gynecology, IVF Unit, ISIDA Women's Hospital , Kiev , Ukraine - - 2014
Abstract Two groups of egg recipients were treated, one in situ (165 patients; 195 cycles) and one after cross-border embryo transportation (340 cycles; 340 cycles) using mobile CO2 incubator. The positive pregnancy rate per cycle was 199/340 (58.6%) and 99/195 (50.7%) in the transportation and the traveling group, respectively (NS). ...
Jhun Katrina M KM 1Department of Pediatrics, Division of Neonatal Medicine, Los Angeles County + University of Southern California, Keck School of Medicine, Los Angeles, CA, - - 2014
We report a case of a giant placental chorioangioma (15.6 cm diameter) complicated by polyhydramnios and severe fetal heart failure. Fetoscopic laser occlusion of a dominant feeding vessel was performed at 29 weeks' gestation and partial devascularization was achieved. In the 33rd week of the pregnancy, the decision was made to ...
Everaert Nele - - 2014
Abstract Objective: We retrospectively compared a protocol using sufentanil and ropivacaine intrathecally with a protocol in which only ropivacaine was administered intrathecally and sufentanil was used epidurally to evaluate whether banning sufentanil from the intrathecal space results in a decreased incidence of adverse fetal heart rate changes. Methods: Some 520 ...
Ugwumadu A A St George's Hospital, London, - - 2014
Original interpretations of fetal heart rate (FHR) patterns equated FHR decelerations with 'fetal distress', requiring expeditious delivery. This simplistic interpretation is still implied in our clinical guidelines despite 40 years of increasing understanding of the behaviour and regulation of the fetal cardiovascular system during labour. The physiological basis of FHR responses ...
Agir Aysen A Department of Cardiology, Faculty of Medicine, Kocaeli - - 2014
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is predominantly a genetically determined heart muscle disorder that is characterized by fibro-fatty replacement of the right ventricular (RV) myocardium.(1)) The clinical spectrum of ARVC may represent from asymptomatic premature ventricular complexes to ventricular tachycardia (VT) and sudden cardiac death (SCD). It is a well-known ...
Lewey Jennifer J Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, - - 2014
Cardiomyopathy during pregnancy is uncommon but potentially catastrophic to maternal health, accounting for up to 11% of maternal deaths. Peripartum cardiomyopathy is diagnosed in women without a history of heart disease 1 month before delivery or within 5 months postpartum. About half of all women will have full myocardial recovery ...
Espinoza Jimmy J Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Hospital Pavilion for Women, Houston, Texas USA (J.E., W.L., M.B.); Department of Obstetrics and Gynecology, William Beaumont Hospital, Royal Oak, Michigan USA (J.E., W.L.); Centro AGB Ultrasonografía, Clínica Sanatorio Aleman, Concepción, Chile (F.V.); Department of Maternal-Fetal Medicine, Institut Clinic de Ginecologia, Obstetricia, i Neonatologia, Hospital Clinic, University of Barcelona, Barcelona, Spain (J.M.M., M.B.); and Department of Obstetrics and Gynecology, University of Rome Tor Vergata, Rome, Italy (G.R.). - - 2014
Accumulating evidence supports a role for 2-dimensional fetal echocardiography in the first trimester of pregnancy for the identification of congenital heart defects. Our objective was to investigate the role of 4-dimensional (4D) sonography in the identification of congenital heart defects between 11 and 15 weeks of pregnancy. This study included ...
Reinhard J J Frauenklinik, St. Marienkrankenhaus Frankfurt, Frankfurt, - - 2014
The objective of this study was to analyze ST segment analyses (STAN) using simultaneous traditional - gold standard invasive (fetal scalp electrode) and newly available non-invasive abdominal fetal electrocardiography (fECG) during delivery.This was a prospective observational study of non-invasive fetal ECG using 5 abdominally sited electrodes (Monica AN24(TM)) against the ...
Lauletta Ana Luisa Fernandes AL Medicine Faculty, University of São Paulo, São Paulo, SP, - - 2014
Objective: the aim of this study was to investigate the patterns of transient FHR accelerations (10 bpm and 15 bpm) in the third trimester of pregnancy, comparing the occurrence of this event before and after the 32nd gestational week. Methods: This is a prospective study comparing the results of the ...
Mahendru Aa A Nottingham University Hospitals NHS Trust, Nottingham, - - 2014
: The incidence of cardiac disease in pregnancy is increasing and cardiac disease remains the leading cause of indirect maternal deaths. Management in pregnancy is highly specialised and requires early diagnosis, referral and multidisciplinary input. The aim of this study was to assess the management and pregnancy in women with ...
Peake L L University of Leicester, Leicester, - - 2014
Advances in management have prolonged the life of many patients with major congenital heart disease (CHD). No national guidelines exist for the counselling of expectant parents with an antenatal diagnosis of a major CHD. All cases of Hypoplastic Left Heart Syndrome (HLHS), Transposition of the Great Arteries (TGA) and Atrio-Ventricular ...
O'Flynn H H North Manchester General Hospital, Pennine Acute NHS Trust, Manchester, - - 2014
Fetal arrhythmias occur in 1-2% of pregnancies, but associated morbidity and mortality is reported in 10%(1). Intravenous magnesium administered in the post natal period is a recognised treatment of fetal ventricular tachycardia(2). We present a case of fetal ectopic beats resolved by correction of abnormal maternal magnesium levels. A 32 ...
Walsh C A CA Fetal Medicine Unit, National Maternity Hospital, Dublin, - - 2014
Objective:To determine the mode of delivery in pregnancies complicated by complex fetal congenital heart disease (CHD).Study Design:Five-year retrospective cohort study at a tertiary fetal medicine center (2007 to 2011). Cases of complex fetal CHD (n=126) were compared with 45 069 non-anomalous singleton infants ⩾500 g to determine rates of emergency intrapartum cesarean ...
Knotts Robert J RJ Department of Medicine, Columbia University Medical Center, 161 Fort Washington Ave, Suite 648, New York, NY - - 2014
As more women with repaired congenital heart disease survive to their reproductive years and many other women are delaying pregnancy until later in life, a rising concern is the risk of cardiac arrhythmias during pregnancy. Naturally occurring cardiovascular changes during pregnancy increase the likelihood that a recurrence of a previously ...
Turitz Amy L AL Division of Maternal-Fetal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 22 W 168th St, PH 16-66, New York, NY - - 2014
While ischemic heart disease in reproductive-age women is rare, cardiac disease is a leading cause of maternal mortality. In turn, coronary artery disease is one of the most common causes of maternal cardiac death. The incidence of coronary artery disease in pregnancy may be rising due to the increasing prevalence ...
Wacker-Gussmann Annette A Department of Neonatology, University Children's Hospital, Tuebingen, - - 2014
Aims Detection and careful stratification of fetal heart rate (FHR) is extremely important in all pregnancies. The most lethal cardiac rhythm disturbances occur during apparently normal pregnancies where FHR and rhythm are regular and within normal or low-normal ranges. These hidden depolarization and repolarization abnormalities, associated with genetic ion channelopathies cannot ...
Maser Raelene E RE Department of Medical Laboratory Sciences, University of Delaware, Newark, DE, USA; Diabetes and Metabolic Research Center, Christiana Care Health System, Newark, DE, USA. Electronic address: - - 2014
The aim of this study was to evaluate the influence of gestational diabetes mellitus (GDM) and positional aortocaval compression on cardiovascular autonomic nervous system (ANS) function in late pregnancy. Pregnant women with (n=31) and without (n=12) GDM were evaluated at 30-35weeks gestation and 2-3months postpartum. Measures of ANS function included ...
Gil E M U EM Department of Diagnostic Imaging, Federal University of Paraná, Curitiba, Paraná, - - 2014
Ultrasonography is a safe and efficient technique for monitoring fetal development and viability. One of the most important and widely used parameters to verify fetal viability is the fetal heart rate (HR). In human medicine, the fetal HR normally oscillates during labor in transient accelerations and decelerations associated with uterine ...
Oian Pål P Women's Health and Perinatology Research Group, University of Tromsø, Department of Obstetrics and Gynecology, University Hospital of Northern Norway, - - 2014
Cardiotocography (CTG) has been recommended for fetal surveillance of high-risk pregnancies in labor in many countries for decades. The test has a high sensitivity, but a low specificity (1), which might have contributed to an increase in cesarean section rate for fetal distress. Therefore, we need a test to identify ...
Wiechec Marcin - - 2014
Abstract Background: Tricuspid regurgitation (TR) is a common sonographic finding during the fetal life. It has been reported in 7% of normal fetuses. It may be associated with aneuploidy and with both cardiac and extracardiac defects. Objectives: In this study, we have looked at the characteristics of fetuses with and ...
Clark John M JM Akron Children's Hospital, Akron, - - 2014
Supraventricular tachycardia is relatively uncommon in pregnancy. Symptomatic arrhythmias create challenges in management during pregnancy. Catheter ablation, the usual curative treatment of choice for supraventricular tachycardia, is often deferred as a result of risks of radiation exposure to the developing fetus. Three-dimensional mapping is a new tool in cardiac electrophysiology, ...
Mastrogiannis Dimitrios S DS Temple University School of Medicine, Philadelphia, - - 2014
In the anomalous fetus, the significance of an abnormal heart rate tracing is not clear because underlying nervous system perturbations may be responsible rather than acidemia. Recently, the National Institute for Child Health and Human Development suggested national nomenclature for fetal heart rate patterns, classified into three categories. The objective ...
Henry Dana D University of California, San Francisco, San Francisco, - - 2014
Maternal cardiac diseases can be severely compromised in the setting of arrhythmias. We compared perinatal outcomes among women with a cardiac arrhythmia with women with other types of cardiac disease. This is a retrospective cohort study of pregnant women with cardiac disease who delivered from 2008 to 2013. Perinatal outcomes ...
Jackson Jessica R JR Sacred Heart Hospital/Florida State OBGYN residency, Pensacola, - - 2014
Prostaglandins play a key role in uterine contractions. Term and preterm myometrium has increased expression of prostaglandin receptors. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the cyclooxygenase receptor and thereby decrease uterine contractions during preterm labor. The NSAID indomethacin has been most extensively studied. Its use has been associated with oligohydramnios and ...
Roche-Kelly Emma E King's College Hospital NHS Foundation Trust, King's College Hospital, London, SE5 9RS, - - 2014
Cardiac disease is the most common cause of death in pregnancy in the UK. Optimal management requires an understanding of the physiological changes of the cardiovascular system during pregnancy, and their impact on existing or developing heart disease. Pregnancy itself is associated with the onset of cardiomyopathy, and a potential ...
Y Shibata S Lecturer, Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital , Tokyo 124-0012, Japan - - 2014
The most serious conditions seen in body stalk anomaly may be the cases which are complicated by ectopia cordis, which is characterized by the abnormal location of the heart outside the thorax. We encountered four cases of body stalk anomaly, which were complicated by ectopia cordis, which were diagnosed in ...
May Linda E LE Division of Surgical Sciences, East Carolina University, Greenville, NC, 27834, USA. Electronic address: - - 2014
Maternal leisure-time physical activity (LTPA) improves cardiac autonomic function in the fetus. The specific physical activity attributes (e.g., mode) that produce this benefit are not well understood. To determine if more time spent performing non-continuous LTPA during pregnancy is significantly associated with lower fetal heart rate (HR) and increased heart ...
Zhou Jiawei J Department of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, Hunan, P.R. - - 2014
The goal of our study was to evaluate the evolution of cardiac findings and assess the pregnancy outcome of fetuses with cardiac asymmetry at mid-gestation. We reviewed all fetuses with cardiac asymmetry at echocardiograms performed at 18-22 weeks of gestation from 2006 through 2013. The data collected included the gestational ...
Fukuda Kenji K Department of Neurosurgery, National Cerebral and Cardiovascular - - 2014
We report two methods of intraoperative fetal heart rate (FHR) monitoring in cases of cerebral arteriovenous malformation surgery during pregnancy. In one case in her third trimester, cardiotocography was used. In another case in her second trimester, ultrasound sonography was used, with a transesophageal echo probe attached to her lower ...
Hersh Sally - - 2014
Electronic fetal heart rate monitoring is the most common form of intrapartal fetal assessment in the United States. Intermittent auscultation of the fetal heart rate is an acceptable option for low-risk laboring women, yet it is underutilized in the hospital setting. Several expert organizations have proposed the use of intermittent ...
Ikeda Sayako S Department of Obstetrics and Gynecology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, - - 2014
The aim of this study was to clarify the association between fetal heart rate (FHR) tracing interpretation levels in the second stage of labor and poor fetal acid-base balance. The database at one tertiary hospital in Nagoya, Japan, was retrospectively reviewed for women with singleton fetuses in cephalic presentation and ...
Tongprasert Fuanglada F Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, - - 2014
The objective of this study was to compare the levels of fetal serum cTnT, representing cardiac injury, and nt-proBNP, representing cardiac volume overload, between fetuses affected and not affected by Hb Bart's disease, as well as between anemic and non-anemic fetuses. One hundred fourteen pregnancies at risk for fetal Hb ...
Herrey Anna S AS Consultant Cardiologist and Honorary Senior Lecturer, UCL, The Heart Hospital, 16-18 Westmoreland Street, London W1G 8PH, UK. Electronic address: - - 2014
Cardiomyopathy encompasses a wide spectrum of heart muscle disease, which can have an impact on the patient's ability to sustain the increased cardiac workload of pregnancy. Pregnancy can also unmask previously unknown cardiomyopathy. The outcome for both mother and baby is often related to the patient's functional class prior to ...
Pike Jodi I JI Children's National Heart Institute, Children's National Medical Center, Washington, - - 2014
Evaluate the utility of early fetal echocardiography in the hands of an experienced fetal cardiology program for detection of congenital heart disease (CHD) in high-risk pregnancies. Review of fetal echocardiograms 12-16 weeks gestation. There were 151 studies in 142 fetuses (mean age 14.5 weeks). Transabdominal imaging was sufficient for 104; transvaginal imaging ...
Windram Jonathan D JD University of Alberta, Mazankowski Heart Institute, Division of Cardiology, University of Alberta Hospital, Edmonton, - - 2014
In women with valvular heart disease, pregnancy-associated cardiovascular changes can contribute to maternal, foetal and neonatal complications. Ideally, a woman with valvular heart disease should receive preconception assessment and counselling from a cardiologist with expertise in pregnancy. For women with moderate- and high-risk valve lesions, appropriate risk stratification and management ...
Mona E Pinto J J Department of Surgery, Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, - - 2014
The uterus plays an essential role in mammalian reproduction and is a target of several hormonal protocols used to improve fertility in cattle. Many studies highlighted the importance of eCG treatment following fixed-time artificial insemination in improving follicular growth, ovulation and pregnancy rates in cattle. Moreover, eCG has been implicated ...
Esin Sertac S Etlik Zubeyde Hanim Women's Health and Teaching Hospital, Department of Perinatology, Ankara, - - 2014
The most common method of antepartum fetal surveillance is the nonstress test (NST). Although it has satisfactory false-negative rates, dubious nonreactive results may challenge the physician. Any method or factor increasing the reactive NST results or shortening the time to attain a reactive test may be considerably useful. Most of ...
Ergin Rahime Nida RN Department of Gynecology and Obstetrics, Bahcesehir University, Istanbul, Turkey (R. Ergin); the Department of Gynecology and Obstetrics, International Hospital, Istanbul, Turkey (Yayla); and the Department of Radiology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey (A. - - 2014
In this report, we describe a rare cause of in utero fetal death, a complex entanglement of the umbilical cord around the fetal neck. At the 16th gestational week of pregnancy, routine fetal ultrasonography showed no fetal heartbeat. Thereafter, the fetus was delivered vaginally in the breech presentation. The neck ...
Senol Utku U Department of Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, - - 2014
Pregnancy is associated with an increased risk of valve thrombosis, hemorrhagic complications, and offspring complications in patients with metallic prosthetic heart valve (MHV). Warfarin treatment is the best regimen against thromboembolic complications, but its use in the first trimester can result in embryopathy. Low molecular weight heparin (LMWH) does not ...
Gevaert Sofie - - 2014
Heart failure is an established predictor of primary cardiac events during pregnancy. Adequate heart failure treatment in pregnant women is hampered by important foetotoxicity of several conventional drugs. Hydralazine with or without long-acting nitrates has been proposed as an alternative for ACE inhibitors or angiotensin receptor blockers. There are no ...
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