Search Results
Results 251 - 300 of 1420
< 1 2 3 4 5 6 7 8 9 10 11 >
Moon-Grady Anita - - 2012
BACKGROUND: The aim of this study was to determine the feasibility of performing complete early fetal echocardiography (FE) at <17 weeks of gestation with comparison with standard FE in the midtrimester (17-23 weeks). METHODS: Fetal echocardiograms obtained in pregnancies studied at <17 weeks at the University of California, San Francisco, ...
Pradhan A D - - 2012
Pregnancy and the need for cardiac catheterization poises a unique challenge that requires the balance of risk and benefit both to the mother and the fetus. Fortunately, the need for radiological invasive procedures for cardiac diagnosis has been markedly reduced with the widespread growth in imaging technology using non-ionizing energies ...
Simpson Lynn L - - 2012
The objective of this review was to assess the evidence that supports cesarean delivery for fetal indications. The main fetal reasons for abdominal delivery include abnormal fetal heart rate patterns in labor, malpresentation, fetal macrosomia, multiple gestation, and both functional and structural fetal abnormalities. Although the level of evidence is ...
Dhanardhono T - - 2012
Introduction: Congenital heart defect (CHD) is a significant cause of neonatal and infant mortality. We aimed to evaluate the incidence and pregnancy outcome of foetuses diagnosed with chromosomally normal CHD in KK Women's and Children's Hospital (KKH), Singapore, in 2008-2009. Methods: We reviewed the medical records of pregnant women who ...
Votino C - - 2012
The detailed study of the fetal cardiac anatomy in the first trimester of pregnancy by means of ultrasound is feasible whether using a transvaginal or a transabdominal approach. There is nowadays enough evidence that ultrasound in the first trimester of pregnancy is a safe procedure provided thermal and mechanical indices ...
Janvier Annie - - 2012
Health care professionals (HCPs) may be involved in counselling women after an antenatal diagnosis of various fetal anomalies. Many pregnant women consider termination of pregnancy (TOP) after antenatal diagnosis of various fetal anomalies. Little is known, however, about the attitudes of HCPs regarding TOP for specific antenatal diagnoses. To determine ...
Tunks Robert D - - 2012
OBJECTIVE: The importance of maternal autoantibody levels in congenital heart block and elucidation of maternal factors that may reduce disease burden require further clarification. STUDY DESIGN: Pregnancies complicated by maternal anti-Ro antibodies from 2007 through 2011 were retrospectively reviewed. RESULTS: In all, 33 women were followed up throughout pregnancy. Semiquantitative ...
Erkinaro Tiina - - 2012
OBJECTIVE: We hypothesized that labetalol and pindolol have no detrimental effects on fetal cardiac function and pulmonary hemodynamics when administered for norepinephrine-induced maternal hypertension in a chronic sheep model of increased placental vascular resistance. Specifically, we investigated the effects of labetalol and pindolol on fetal cardiopulmonary responses to acute hypoxemia. ...
Dhiman Niharika - - 2012
A 22-year-old second gravida presented to the antenatal clinic at 28 weeks of gestation with frequent fainting attacks (2-3 episodes/day), palpitations and dyspnea (New York Heart Association Functional Classification II). Her pulse rate was 40 b.p.m. A 12-lead electrocardiogram and 24-h Holter revealed complete heart block. A transvenous permanent pacemaker (ventricular ...
Statile Christopher J - - 2012
Objective: High cardiac output lesions are associated with an increased risk of fetal death due largely to cardiac failure and hydrops fetalis. The cardiovascular profile score (CVPS) has been used to characterize cardiovascular well-being, and related to fetal outcomes inother fetal conditions. We hypothesized that elevated combined cardiac output (CCO) ...
Estensen Mette-Elise - - 2012
Objectives: During pregnancy, the cardiovascular system adapts to the metabolic needs of mother and fetus. The effects of this adaptation on left ventricular (LV) function have not been well documented. The aim of this study was to evaluate LV systolic and diastolic function during normal pregnancy by non-invasive measures of ...
Melchiorre Karen - - 2012
PURPOSE OF REVIEW: To review the published data on maternal cardiac adaptation to pregnancy. RECENT FINDINGS: Normal pregnancy is characterized by significant changes in the cardiovascular system. Studies on systemic arterial system and heart remodelling in pregnancy provide somewhat uniform results. In normal pregnancy, left ventricle mass, cardiac output and ...
Katsuragi Shinji - - 2012
Abstract Objective: To determine whether a rule-based system for fetal heart rate interpretation can result in reduced metabolic acidemia without increasing obstetrical intervention. Methods: Rates of vacuum-assisted delivery and Cesarean sections, and umbilical artery pH and base excess values were determined over a 5-year period in a single hospital with ...
Park Young-Sun - - 2012
BACKGROUND: It has been reported that breech fetuses have inferior neurological outcomes regardless of mode of delivery, raising the possibility that in utero neurological impairment is more frequent in breech fetuses, possibly contributing to malpresentation. AIMS: To assess differences between the cardiovascular autonomic nervous systems (ANSs) of breech and cephalic ...
Frank Jennifer - - 2012
The first symptoms of previously undiagnosed congenital heart disease may become apparent during pregnancy. It is important to recognize structural heart lesions since they require additional monitoring during the prenatal, peripartum, and postpartum periods and are associated with increased maternal and fetal morbidity and mortality. We report a case of ...
Sebastian Vinod A - - 2012
OBJECTIVE: Fetal cardiac surgery is a potential innovative treatment for certain congenital heart defects that have significant mortality and morbidity in utero or after birth, but it has been limited by placental dysfunction after fetal cardiac bypass. We have used the TinyPump device for fetal cardiac bypass in sheep fetuses ...
Ohashi Yuki - - 2012
Abstract Objective: The safe and effective methods of fetal anesthesia/analgesia during ultrasound guided direct fetal procedure is yet to be determined. The authors investigated whether maternal diazepam/fentanyl administration meets this purpose. Methods: The medical/anesthesia records were retrospectively reviewed in cases between 2001 to 2010 at a tertiary perinatal center. Success ...
Tanha Fateme Davari - - 2012
PURPOSES: To evaluate the efficacy of two routes of administration of misoprostol (sublingual and vaginal) for medical termination of second trimester pregnancies. METHODS: One hundred and thirty-four women referred for second trimester termination were enrolled in this randomized clinical trial. They were divided to receive 400 μg every 6 h misoprostol either ...
Serra V - - 2012
Please cite this paper as: Serra V, Perales A, Meseguer J, Parrilla J, Lara C, Bellver J, Grifol R, Alcover I, Sala M, Martínez-Escoriza J, Pellicer A. Increased doses of vaginal progesterone for the prevention of preterm birth in twin pregnancies: a randomised controlled double-blind multicentre trial. BJOG 2012; DOI: ...
Raymond Elizabeth G - - 2012
BACKGROUND: The dose of mifepristone approved by most government agencies for medical abortion is 600 mg. Our aim was to summarize extant data on the effectiveness and safety of regimens using the widely recommended lower mifepristone dose, 200 mg, followed by misoprostol in early pregnancy and to explore potential correlates ...
Endicott S - - 2012
The majority of pregnant women take prescription drugs during their pregnancy. Given the multitude of physiologic changes incumbent in pregnancy, accurate clinical trial data on drugs in pregnancy are crucial. This report summarizes the 264 registered clinical trials in the past two years. With many of these drug trials being ...
Elkayam Uri - - 2012
In 1971, Demakis and colleagues established the term peripartum cardiomyopathy (PPCM) and defined it by criteria based on the clinical profile of their patients. With the recognition that these criteria are arbitrary and that PPCM often presents earlier in pregnancy, the definition of PPCM has been recently updated by a ...
Ye-Lin Y - - 2012
Abdominal electrocardiogram (AECG) recording is a non-invasive method to assess fetal well-being during both pregnancy and delivery. However, AECG recording is contaminated by a series of physiological interferences which make difficult the extraction of morphological and temporal parameters of fetal ECG from the raw signals. In this work, it is ...
Fanelli A - - 2012
Twin pregnancies carry an inherently higher risk than singleton pregnancies due to the increased chances of uterine growth restriction. It is thus desirable to monitor the wellbeing of the fetuses during gestation to detect potentially harmful conditions. The detection of fetal heart rate from the maternal abdominal ECG represents one ...
Fodor Gabor - - 2012
A large proportion of congenital heart diseases (CHD) remain undetected during pregnancy or even after birth. Many of them generate turbulent blood flow, resulting heart murmur. Doppler ultrasound cardiotocography (CTG) is suitable for the assessment of the fetal heart rate and some derived parameters, but it is inadequate for detecting ...
Wallwitz Ulrike - - 2012
Abstract Objective: To describe the development of the integrative capacity of the fetal autonomic nervous system (ANS) accor\xadding to gestational age and emerging behavioral states, assuming that developing integrative ANS functions are reflected in increasing autocorrelation of fetal heart rate and fetal heart rate variability markers. Methods: Magnetocardiograms of 114 ...
Yonkers Kimberly A - - 2012
The objective was to compare the efficacy of motivational enhancement therapy coupled with cognitive behavioral therapy (MET-CBT) to brief advice for treatment of substance use in pregnancy. This was a randomized, parallel, controlled trial that was yoked to prenatal care and delivered at hospital outpatient clinics. We enrolled 168 substance-using ...
O'Brien John M - - 2012
The safety of supplemental progestin therapy during pregnancy reflects whether an agent exclusively promotes or potentially inhibits progestational cellular functions and whether treatment incites a metabolic derangement or other pathophysiology to initiate rare untoward events. No safety signal has been identified from intravaginal administration of natural progesterone from phase III ...
Nishtar A - - 2012
Vasa praevia can cause acute severe fetal haemorrhage prior to or during rupture of the membranes, contributing to perinatal morbidity and mortality. There are no large prospective studies relating to vasa praevia and there is no place for a randomised controlled trial as it would be ethically unjustifiable given the ...
Amitabh Priya - - 2012
Ectopia cordis is a rare congenital anomaly. Congenital anomaly scan can detect it at 18-23 weeks of gestation. Four chamber view of the heart in routine fetal anomaly scans at >18 weeks is the most effective technique to detect CHD prenatally.
Kohls Graciela - - 2012
OBJECTIVE: To investigate the effect of stopping progesterone (P) support at week 5 versus week 8 on ongoing pregnancy rate after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI). DESIGN: Prospective, randomized, controlled trial. SETTING: University-affiliated infertility center. PATIENT(S): A total of 220 patients with intrauterine pregnancy demonstrated by transvaginal ultrasound after ...
da Silva Ana Luisa B - - 2012
OBJECTIVES: To verify non-inferiority of the clinical pregnancy rate of Early hCG administration (leading follicle sizes within 16.0-16.9mm in diameter) compared to Late hCG administration (leading follicle sizes within 18.0-18.9mm in diameter). STUDY DESIGN: Prospective randomized trial. Six hundred and twelve infertile women candidates for intrauterine insemination (IUI) received HP-hMG ...
Goshtasebi A - - 2012
A randomized clinical trial examined the efficiency and tolerability of twice weekly versus daily iron supplementation during pregnancy. A total of 370 pregnant women were randomly assigned to receive either daily or twice weekly iron supplementation during pregnancy. There were no significant differences in initial and delivery haemoglobin and haematocrit ...
la Grange J - - 2012
Objective: To compare efficacy of sterilization reversals by laparotomy versus laparoscopy. Design: Meta-analysis. Search Strategy: Electronic searches were carried out for randomized controlled trials and retrospective and prospective clinical studies. Search engines such as PubMed, Science Direct, Medline and the Cochrane database were made use of. Our restrictions were English ...
Liem Sophie Ms - - 2012
ABSTRACT: The initial sample size calculation in our protocol (Hegeman et al, BMC Pregnancy Childbirth, 2009, 9:44) was based on the expected proportion of 'bad neonatal outcome' in the intervention group (3.9%) and control group (7.2%) and accounts for the fact that the outcomes in children form multiple pregnancies are ...
Consonni Sílvio Roberto - - 2012
Impairment of pelvic organ support has been described in mice with genetic modifications of the proteins involved in elastogenesis, such as lysyl oxidase-like 1 (LOXL1) and fibulin 5. During pregnancy, elastic fiber-enriched pelvic tissues are modified to allow safe delivery. In addition, the mouse pubic symphysis is remodeled in a ...
Comhaire F - - 2012
To compare the clinical efficiency of different modes of treatment of infertile couples and to estimate the possible benefit of nutraceutical food supplementation (NFS), the numbers needed to treat (NNT) was calculated in 4143 infertile couples based on controlled trials in recent literature and personal data. The NNT expresses the ...
Checa Miguel A - - 2012
OBJECTIVE: To assess the efficacy and safety of hCG to induce follicular stimulation. DESIGN: Systematic literature searches of PubMed, EMBASE, CENTRAL, and SciSearch databases. Randomized controlled trials (RCTs) using hCG in early or late follicular phases were included. SETTING: Three reproductive medicine services of gynecology in Spain and two universities. ...
Stanek Jerzy - - 2012
OBJECTIVE: To identify by an inductive statistical analysis mutually similar and clinically relevant clinicoplacental clusters. STUDY DESIGN: Twenty-nine maternofetal and 49 placental variables have been retrospectively analyzed in a 3382 case clinicoplacental database using a hierarchical agglomerative Ward dendrogram and multidimensional scaling. RESULTS: The exploratory cluster analysis identified 9 clinicoplacental ...
Stoch Yonit K - - 2012
An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a ...
Babbar Shilpa - - 2012
The purpose of this review article is to evaluate the peripartum outcomes of yoga during pregnancy, including the postpartum period and lactation. The PubMed database was analyzed from January 1970 to January 2011. We identified five prospective observational studies (n = 575) and three randomized clinical trials (RCTs; n = ...
Sibeko Sengeziwe - - 2012
The distinctive feature of the human immunodeficiency virus (HIV) epidemic in Sub-Saharan Africa is the burden on women, in particular young women of reproductive age. Consequently, most late-phase effectiveness microbicide clinical trials are conducted in sub-Saharan Africa where fertility rates are high. Because late-phase clinical trials are conducted over prolonged ...
Kang Sang Min - - 2012
To compare the clinical outcomes of elective single morula embryo transfer (eSMET) versus elective single blastocyst embryo transfer (eSBET) in selected patients. This study was a retrospective study which analyzed for 271 cycles in women under 37 years of age who are undergoing their first or second trial of in ...
Azim Hatem A HA - - 2012
Only few case reports describe the pregnancy course and outcome of breast cancer patients, who were under treatment with trastuzumab at the time of conception or who have completed trastuzumab therapy before becoming pregnant. The HERA trial is a large phase III randomized clinical trial in which patients with early ...
Canoy James M - - 2012
The imaging changes in the breast associated with pregnancy and the perinatal period may not only deviate from the baseline appearance for each patient, but may also mimic disease or confound evaluation of disease. The hormonal changes can influence a range of disorders, from benign or inflammatory changes to malignant ...
Adzick N Scott - - 2012
The rationale for in utero repair of myelomeningocele (MMC) in the context of pathologic observations, animal models, and outcomes from the initial experience with human fetal MMC repair is presented. This has now culminated in a randomized trial, Management of Myelomeningocele Study, the findings of which are listed. The story ...
Schenone M H - - 2012
Placental abruption is a serious condition that increases perinatal morbidity and mortality. Clinical prevention and treatment options are limited, especially in human preterm deliveries. Knowledge of the mechanisms that keep the placenta in place during pregnancy is critical for developing strategies for the prevention of abruption. Failure of physiological transformation ...
Takci Zennure - - 2012
Tinzaparin sodium is a low molecular weight heparin formed by the enzymatic degradation of porcine unfractionated heparin, and is effective in the prevention and treatment of thromboembolic disease. We report a 31-year-old female patient with a history of recurrent pregnancy loss due to thrombophilia, who developed nail discoloration after 8 ...
Ramsay Gillian - - 2012
Cardiac arrest is a rare occurrence in pregnancy and may be related to obstetric or medical causes. Pregnancy is associated with profound physiologic changes that prepare the gravida for the challenges of labor and delivery, and resuscitation of the pregnant patient needs to take these changes into consideration. Cardiac output ...
Dijkmans Anneke C - - 2012
PURPOSE OF REVIEW: Parvovirus B19 infection is often considered a mild and self-limiting disease of minor clinical importance. This review aims to raise awareness of recently discovered potentially devastating consequences of this infection in pregnancy, and provides updated guidelines on diagnosis and management. RECENT FINDINGS: In contrast to previous beliefs, ...
< 1 2 3 4 5 6 7 8 9 10 11 >