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Kobayashi Tomoko T Department of Obstetrics and Gynecology, Wakayama Medical University, Wakayama, - - 2014
Acute fatty liver of pregnancy (AFLP) is a devastating disorder of the maternal liver in the third trimester. Recent studies have demonstrated an association between AFLP and fetal fatty acid oxidation disorders. Here, we report a case of AFLP caused by fetal mitochondrial trifunctional protein (TFP) deficiency. A 21-year-old parous ...
Tain You-Lin YL - - 2014
Nitric oxide (NO) deficiency induced by the NO synthase (NOS) inhibitor N(G)-nitro-L-arginine-methyl ester (L-NAME) resulted in hypertension. L-citrulline (CIT) can be converted to L-arginine to generate NO. We examined whether maternal CIT supplementation can prevent L-NAME-induced programmed hypertension. Pregnant Sprague-Dawley rats were assigned to four groups: control, L-NAME, control + ...
Huhta James J aPerinatal Cardiology, All Children's Hospital, John Hopkins Medicine, Baltimore, Maryland bDepartment of Pediatrics, USF School of Medicine, Tampa, Florida, - - 2014
Provide a rationale for attempting prevention of congenital heart defects (CHDs). Prevention of neural-tube defects can be achieved with preconceptional use of folic acid. Extrapolating results from animal studies to human pregnancy shows that folate deficiency as well as one-time exposure to environmental factors in the first 2 to 3 ...
Ozias Marlies K MK a Department of Dietetics and Nutrition , University of Kansas Medical Center , Kansas City , Kansas (M.K.O., E.H.K., D.N.C., S.A.S., S.E.C.), and Department of Psychology , University of Kansas , Lawrence , Kansas - - 2014
Objective: The objective of this longitudinal study was to determine what typical vitamin D predictors influence the change in vitamin D status from mid-pregnancy to birth. Methods: Plasma 25-hydroxyvitamin D [25(OH)D] was determined at mid-pregnancy (8-20 weeks gestation) and following birth (n = 193). Usual predictors of vitamin D status ...
Wei Shu Qin SQ Department of Obstetrics and Gynecology, Saint-Justine Hospital, University of Montreal, Montreal, Quebec, - - 2014
This article presents an overview of the most recent scientific evidence of the role of maternal vitamin D on pregnancy outcomes, with a particular emphasis on those articles in the English-language literature published between 1 January 2013 and 1 July 2014 in PubMed. Low levels of vitamin D status, as ...
Fabris Alberta A IVI-Madrid, Rey Juan Carlos University, Madrid, - - 2014
To investigate the correlation between total and bioavailable serum 25-OH vitamin D and the pregnancy rate in recipients of donated oocytes. Retrospective study. University-affiliated private IVF center. A total of 267 patients who were referred to our clinic for oocyte donation from June 2013 to December 2013. Serum analysis of vitamin ...
Reichetzeder Christoph C Institute of Nutritional Science, University of Potsdam, Potsdam-Rehbrücke, - - 2014
Background/Aims: Cardiovascular disease partially originates from poor environmental and nutritional conditions in early life. Lack of micronutrients like 25 hydroxy vitamin D3 (25OHD) during pregnancy may be an important treatable causal factor. The present study explored the effect of maternal 25OHD deficiency on the offspring. Methods: We performed a prospective ...
Parisi Francesca F Department of Mother and Child, Luigi Sacco University Hospital, Milan, - - 2014
Background: As nutritional deficiencies are known to lead to adverse pregnancy outcomes, a woman's nutritional status should be assessed preconceptionally with the goal of optimizing maternal, fetal and infant health. Worldwide micronutrient intakes do not fit pregnancy requirements, so that their supplementation is recommended from the beginning of pregnancy in ...
Salam Rehana A RA Center of Excellence in Women and Child Health, Aga Khan University, Karachi, - - 2014
Background: Malnutrition, including micronutrient deficiencies, remains one of the major public health challenges, particularly in low-to-middle-income countries. Micronutrient deficiencies affect people of all ages, but its effects appear more devastating in pregnant women and children. Poor maternal nutrition contributes to at least 20% of maternal deaths and increases the probability ...
Ugwu E O EO Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, - - 2014
Background: Anemia in pregnancy is highly prevalent among antenatal clinic attendees in Enugu, Nigeria despite the practice of routine iron supplementation in pregnancy. The major problem with iron supplementation in pregnancy is compliance, and this may be a potential driver to the persistent high prevalence of anemia in this population. ...
- - 2014
Pregnancy increases the demand for vitamins, including vitamin D. Data on effects of vitamin D deficiency for pregnant woman and fetus available in Poland are scarce. The aim of this study was to evaluate vitamin D3 concentration in pregnant women and its influence on pregnancy course, health of pregnant women ...
Torres-Sánchez Luisa L Center for Population Health Research, National Institute of Public Health, Av. Universidad 655, Col. Sta María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico, - - 2014
In this study, we evaluated the effects of dietary intake of vitamin B12 and folate during pregnancy and their interactions with maternal polymorphism of MTHFR (677C>T; 1298A>C) on intrauterine development. Anthropometric parameters were obtained from 231 newborns that belong to a prospective birth cohort in Morelos, Mexico. Maternal dietary intake ...
Wilgen Urs U Pathology Queensland, Department of Chemical Pathology, Royal Brisbane and Women's Hospital, Herston Road, Herston 4029, Queensland, Australia; University of Queensland, School of Medicine, Brisbane, St Lucia 4072, Queensland, Australia. Electronic address: - - 2014
Point-of-care testing for β-hCG has been widely advocated to allow rapid diagnosis/exclusion of pregnancy in the emergency department. A quantitative blood β-hCG assay has the additional benefit of being able to monitor the viability of pregnancy, using serial measurements, to determine the appropriate expected increase in β-hCG levels over time ...
So Jane J Stony Brook University Hospital, Stony Brook, - - 2014
Preeclampsia occurs in 6-8% of pregnancies and is the second leading cause of maternal mortality in the United States. Preeclampsia is associated with HELLP (Hemolysis, Elevated Liver enzymes and Low Platelet count) syndrome and it has become a common practice to evaluate for the syndrome with laboratory testing in all ...
Mor Amir A Maimonides Medical Center, Brooklyn, - - 2014
Meconium-stained amniotic fluid occurs in approximately 12% of all pregnancies. Although most pregnancies with meconium-stained amniotic fluid end with no fetal or neonatal complications, there is still a significant number that result in immediate life-threatening complications to the neonate such as meconium aspiration syndrome. Meconium aspiration syndrome still poses a ...
Balssa Frédéric F Laboratoire des Courses Hippiques, 15 rue de Paradis, 91370 Verrières le Buisson, France. Electronic address: - - 2014
5(10)-estrene-3β,17α-diol is an essential reference material for doping analysis in horse-racing laboratories. It is used to detect misuse, for doping purpose, of the pregnancy status in the mare. Its stereoselective synthesis from 17β-estradiol-3-methyl ether (prepared from estrone or 17β-estradiol) was performed in four steps: (1) Mitsunobu inversion of the 17β-alcohol; ...
Panda Akhila Kumar AK Department of Neurology, Institute of Human Behaviour and Allied Sciences, Delhi, - - 2014
Parry-Romberg syndrome (PRS) with hemimasticatory spasm (HMS) is quite an uncommon overlapping phenomenon which very often mimics jaw closing dystonia. A previously healthy 35-year-old female, during her 5(th) month of pregnancy started developing intermittent unilateral painful spasms of jaw while conversation, clinching of teeth, or eating, which led to frequent ...
Morton Susan B - - 2014
To describe iron status at birth in a population sample of children. Cord blood samples were obtained at birth from 131 infants enrolled in the cohort study Growing Up in New Zealand. Cord blood serum ferritin (SF) and haemoglobin (Hb) concentrations were measured and associations of SF and Hb with ...
Macdonald Mary Ellen ME Faculty of Dentistry, McGill University, Montréal, - - 2014
For 25 years, Inuit midwives have provided perinatal and newborn care for about 90% of the pregnancies in northwestern Quebec. Patients in this region continue to have high rates of preventable nutritional deficiencies. The objective of this study was to explore the perceptions of professional midwives and students about what ...
Park Sunmin S Department of Food & Nutrition, Hoseo - - 2014
The association between vitamin D deficiency in the first trimester and GDM development remains controversial in various ethnicities. We prospectively assessed whether pregnant women with vitamin D deficiency during early pregnancy had an increased likelihood of GDM development or poor fetal growth or pregnancy outcomes compared to those with sufficient ...
Gür Esra Bahar EB Department of Obstetrics and Gynecology, Şifa University Faculty of Medicine, İzmir, - - 2014
The aim of this study was to determine the prevalence and the predictive factors of vitamin D deficiency in pregnancy and the compliance with "The National Vitamin D Support Program" at Turkey's easternmost and westernmost provinces. Lifestyles of women at 24-28 weeks of pregnancy were assessed using a questionnaire form, ...
Burke Rachel M RM Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd. NE, Atlanta, GA 30322, USA. - - 2014
Iron deficiency is a global problem across the life course, but infants and their mothers are especially vulnerable to both the development and the consequences of iron deficiency. Maternal iron deficiency during pregnancy can predispose offspring to the development of iron deficiency during infancy, with potentially lifelong sequelae. This review ...
Bestwick Jonathan P JP Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, - - 2013
Thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentrations vary during pregnancy and conventional units can vary between laboratories. Reference ranges are widely quoted but are arbitrary and do not allow for inter-laboratory differences or gestational age. We therefore explored using multiples of the median (MoM) values to overcome these ...
Ziebe Søren - - 2013
Morphometric and morphokinetic approaches toward embryo quality assessment have for many years been difficult due to technical limitations. Today, with improvements in laboratory techniques and subsequent quality, we have a better understanding of the morphometric and kinetics of embryo development. Fertility clinics are moving from "sensing" embryo quality to measuring ...
Bliddal Sofie - - 2013
Correct interpretation of thyroid status during pregnancy is vital to secure fetal development. Pregnancy-related changes in maternal thyroid status necessitate use of gestational-age-specific reference ranges. We investigated between-laboratory reproducibility of thyroid reference ranges in pregnant women. Comparison of two longitudinal prospective cohort studies including 255 (cohort 1) and 101 (cohort ...
Garla Vishnu V Department of Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington WV, USA. - - 2013
A 31 year old woman who was 16 weeks pregnant was admitted because of headache, blurred vision, excessive weight gain, and hirsutism. Laboratory tests showed low adrenocorticotropic hormone (ACTH) and elevated serum and urinary cortisol. Magnetic resonance imaging showed a left adrenal mass. Left adrenalectomy was done, and histopathology showed ...
Teng Weiping W Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang, - - 2013
Hypothyroidism is the most common pregnancy-related thyroid disorder, affecting 3-5% of all pregnant women. Subclinical hypothyroidism is more common than is overt hypothyroidism, and is usually defined as a serum thyroid-stimulating hormone (TSH) concentration greater than the pregnancy-specific reference range for each laboratory value, or by serum TSH concentrations greater ...
Gadgil Meghana D - - 2013
Abstract Objective: Bariatric surgery can reduce the risk of obesity-related complications of pregnancy, but may cause essential nutrient deficiencies. To assess adherence to laboratory testing guidelines, we examined frequency of testing for and diagnosis of deficiency during preconception and pregnancy using claims data in women with a delivery and bariatric ...
Mehlhaff Krista M - - 2013
Brodifacoum, a superwarfarin, is a common household agent used for rodenticides. We present a case of maternal brodifacoum ingestion that resulted in neonatal death. A 19-year-old primigravid woman presented at 32 weeks of gestation with spontaneous mucosal bleeding. Her fetus showed evidence of acidosis on external fetal monitoring. Laboratory values ...
Gawron Lori M - - 2013
Context.-Management of second-trimester intrauterine fetal demise via dilation and evacuation results in nonintact specimens for pathologic examination. Surgical pathology examination is often mandated; however, evidence on expected findings and specimen evaluation guidelines are lacking. Objectives.-To assess pathologic findings of nonintact, second-trimester fetal demise specimens, through comparison of anatomic abnormalities identified ...
Tomlinson Mathew - - 2013
Reports on the influence of semen parameters on natural or assisted pregnancy are contradictory, suggesting that the many confounding variables which contribute to outcome have not been taken into account. However, it is possible to derive some consensus for both natural and assisted conception by focussing on studies which use ...
Nelson David B - - 2013
Our aim was to provide a description of clinical and laboratory finding: pregnancy outcomes in women with acute fatty liver of pregnancy (AFLP). We also characterize the duration of recovery of multiorgan system dysfunction that begins after delivery. All women who were admitted to Parkland Hospital with AFLP were identified; ...
De Neubourg D D Department of Obstetrics and Gynaecology, LUFC, University Hospitals Leuven, Leuven, - - 2013
What is the effect of a legal limitation of the number of embryos that can be transferred in an assisted reproductive technology (ART) cycle on the multiple delivery rate? The Belgian national register shows that the introduction of reimbursement of ART laboratory costs in July 2003, and the imposition of ...
Belvini D - - 2013
This article describes prenatal diagnosis (PND) of haemophilia B (HB) within the framework of Italian haemophilia centres and genetics laboratories. The study details the experience from six haemophilia genetic centres (three in the North, one in the Centre and two in the South of Italy) and summarizes the different techniques ...
Africa Charlene Wj - - 2013
Introduction: Bacterial vaginosis (BV) has been associated with pelvic inflammatory disease, adverse pregnancy outcomes, increased susceptibility to sexually transmitted infections and infertility. Diagnosis of BV should be rapid, reliable and safe. This is especially vital in pregnant women where intervention may be necessary for the well-being of both the mother ...
Lovrencić Marijana Vucić - - 2013
An increasing prevalence of gestational diabetes has become a very challenging task in prenatal care worldwide. International Association of Diabetes and Pregnancy Study Groups (IADPSG) has recently issued recommendations on the diagnosis and classification of hyperglycaemia in pregnancy. These recommendations, the first to provide harmonised, evidence-based criteria for the diagnosis ...
Hinrichs Katrin - - 2012
This paper reviews current equine assisted reproduction techniques. Embryo transfer is the most common equine ART, but is still limited by the inability to superovulate mares effectively. Immature oocytes may be recovered by transvaginal ultrasound-guided aspiration of immature follicles, or from ovaries postmortem, and can be effectively matured in vitro. ...
Dias Monike L - - 2012
BACKGROUND: High homology of GH with placental GH (pGH) and hPL frequently resulted in falsely high GH levels in competitive immunoassays during pregnancy. However, in immunometric assays, falsely high or low GH levels can result from GH-like molecules binding to both or only one monoclonal antibody. Since our GH-IFMA assay ...
Basavaraju Anuradha - - 2012
Pregnancy gingivitis is a major oral infection. Periodontium acts as a reservoir of inflammatory mediators and sub gingival biofilms of bacteria. To evaluate the anaerobic oral microbial flora in pregnant women before delivery and after delivery by comparing them with control group. The study group included fifteen cases of pregnant ...
Bubonja-Sonje Marina - - 2012
Abstract Background: Listeria monocytogenes usually causes mild maternal illness, but can be devastating to the fetus. Case: Listeriosis in a pregnant patient successfully treated with empiric antibiotic therapy is described. After induced delivery, despite severe placental infection, a healthy infant was born. Additionally, archived placental specimens with similar pathological manifestation ...
Ema Makoto - - 2012
Historical control data on rabbit prenatal developmental toxicity studies, performed between 1994-2010, were obtained from 20 laboratories, including 11 pharmaceutical and chemical companies and nine contract laboratories, in Japan. In this paper, data were incorporated from a laboratory if the information was based on 10 studies or more. Japanese White ...
Ghartey Jeny P - - 2012
Genital tract secretions exhibit bactericidal activity against Escherichia coli. We hypothesized that this defense may be modulated during pregnancy. Secretions were collected by vaginal swab from 70 pregnant women (35-37 weeks' gestation) and 35 nonpregnant controls. We mixed E coli with swab eluants or control buffer and colonies enumerated to ...
Hawa Nadim - - 2012
The safety of laparoscopic management of adnexal masses in pregnancy has been documented. Herein we report laparoscopic removal during pregnancy of a cystically degenerated leiomyoma of the sigmoid colon, which had been mistaken for an adnexal mass. When smooth muscle gastrointestinal tumors are observed, it is important that they be ...
Draçini Xh - - 2012
Introduction. Acute intestinal obstruction in pregnancy is a rare, but life-threatening complication associated with high fetal and maternal mortality. Case report. A 20-year old gravida presented with a 24 hour history of several episodes of vomiting, complete constipation and severe crampy abdominal pain. The patient was admitted with the diagnosis ...
Giorgakis E E Royal London Hospital , Barts and The London NHS Trust, London, - - 2012
Endometriosis is a common disorder in women of reproductive age. A rare localization is the appendix, which, in most cases, is an incidental finding during appendectomies. The incidence of symptomatic appendiceal endometriosis or endometrial appendicitis might be increased in pregnancy. Moreover, endometrial appendicitis in pregnancy is more likely to present ...
Tam Teresa - - 2012
Abstract Objective: The purpose of the study is to evaluate the incidence of women with prior GBS genital colonization who have recolonization in subsequent pregnancies. Methods: This is a retrospective, cohort study of patients with a prior GBS genital colonization in pregnancy and a subsequent pregnancy with a recorded GBS ...
Chung Judith H - - 2012
: Fetal epignathus, a teratoma arising from the oropharynx that may be lethal, can be diagnosed prenatally. : A 29-year-old woman, gravida 1, was evaluated for an elevated alpha-fetoprotein level. Imaging evaluation revealed a fetal epignathus without intracranial extension. Preterm labor necessitated delivery at 27 5/7 weeks of gestation with ...
Mortimer R H - - 2012
CONTEXT: The thyroid hormone and retinol binding protein transthyretin (TTR) is synthesised by human trophoblasts. Polarised JEG-3 choriocarcinoma cells grown in bicameral chambers secrete TTR predominantly apically but also basally and these cells and human trophoblasts also take up TTR suggesting that there may be a placental TTR shuttle that ...
Bosco Cleofina - - 2012
AIMS: To examine the causes of variability in the effect of maternal drinking on the foetus, with particular reference to the pattern, frequency and duration of the period of drinking, differences in maternal, foetal and placental metabolism of ethanol/acetaldehyde, and genetic factors. METHODS: Narrative review of published studies of the ...
Mitchell R T RT Medical Research Council/University of Edinburgh Centre for Reproductive Health, The Queen's Medical Research Institute, Edinburgh Royal Hospital for Sick Children, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland, United Kingdom. - - 2012
Phthalates are ubiquitous environmental chemicals. Fetal exposure to certain phthalates [e.g. di-n-butyl phthalate (DBP)] causes masculinization disorders in rats, raising concern for similar effects in humans. We investigated whether DBP exposure impairs steroidogenesis by the human fetal testis. The aim of the study was to determine effects of DBP exposure ...
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