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Vogt M M Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum - - 2014
Purpose: Tissue Doppler imaging (TDI) allows the noninvasive quantification of global and regional myocardial function. Since there are changing loading conditions during pregnancy, this study aimed to determine maternal myocardial adaptation in normal pregnancy with TDI and tracking of the heart cycle. Patients and Methods: 106 pregnant women, mean age ...
Widen E M EM 1] New York Obesity Nutrition Research Center, St. Luke's-Roosevelt Hospital, New York, NY, USA [2] Institute of Human Nutrition and Department of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, USA [3] Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, - - 2014
Prevalence of overweight and obesity has risen in the United States over the past few decades. Concurrent with this rise in obesity has been an increase in pregravid body mass index and gestational weight gain affecting maternal body composition changes in pregnancy. During pregnancy, many of the assumptions inherent in ...
Johnson Mary Lynn ML M Johnson, Animal Sciences, North Dakota State University, Fargo, 58108, United - - 2014
Scrapie in sheep is spread laterally by placental transmission of an infectious misfolded form (PrPSc) of a normal prion protein (PrPC) used as a template in PrPSc formation. We hypothesized that PrPC would be expressed in uterine and placental tissues and estradiol-17B (E2) would affect uterine PrPC expression. PrPC expression ...
Mathur Nidhee N Department of Obstetrics and Gynecology, University of Chicago Recurrent Pregnancy Loss Program, University of Chicago, Chicago, - - 2014
To assess the utility of comparative genomic hybridization (CGH) and reflex microsatellite analysis (MSA) for chromosome analysis of preserved miscarriage tissue. Observational study. Academic recurrent pregnancy loss program. Patients with recurrent early pregnancy loss, defined as two or more miscarriages at <10 weeks, and at least one preserved miscarriage specimen sent ...
Parsley Laura M LM School of Zoology, University of Tasmania, Sandy Bay Campus, Private Bag 5, 7000 Tasmania, Australia. Electronic address: - - 2014
Aromatase is a key regulator of circulating testosterone (T) and 17-β-oestradiol (E2), two steroids which are critical to the development, maintenance and function of reproductive tissues. The role of aromatase in sexual differentiation in oviparous (egg-laying) reptiles is well understood, yet has never been explored in viviparous (live-bearing) reptiles. As ...
Ebrahimi Mahbod - - 2014
Ovarian pregnancy is a rare form of extra uterine pregnancy. Serous cyst adenoma is a benign variant of epithelial cell tumors of ovary. The coexistence of a cyst adenoma with an ovarian pregnancy in the same ovary is extremely rare. Some studies suggested that infertility or ovulation-inducing drugs can be ...
Huda Shahzya S SS Women and Children's Unit, Forth Valley Royal Hospital, Larbert, United - - 2014
Obesity increases preeclampsia risk, and maternal dyslipidemia may result from exaggerated adipocyte lipolysis. We compared adipocyte function in preeclampsia with healthy pregnancy to establish whether there is increased lipolysis. Subcutaneous and visceral adipose tissue biopsies were collected at caesarean section from healthy (n=31) and preeclampsia (n=13) mothers. Lipolysis in response ...
Kudesia Rashmi - - 2014
Determination of fetal aneuploidy is central to evaluation of recurrent pregnancy loss (RPL). However, obtaining this information at the time of a miscarriage is not always possible or may not have been ordered. Here we report on "rescue karyotyping", wherein DNA extracted from archived paraffin-embedded pregnancy loss tissue from a ...
Idilman Ilkay S IS Department of Radiology, Faculty of Medicine, Hacettepe University, Ankara, - - 2014
Renal angiomyolipoma is a hamartomatous, benign tumor composed of blood vessels, fatty tissue and smooth muscle cells, and is often detected incidentally. It can also be associated with the tuberous-sclerosis complex (TSC). Pregnancy and use of oral contraceptives are known to be associated with an increased risk of tumoral rupture ...
Klibanov Olga M OM Wingate University School of Pharmacy, Wingate, NC, - - 2014
To report a case of infective panniculitis in a morbidly obese, pregnant woman, which was successfully treated with daptomycin. A 34-year-old, 27-week pregnant, morbidly obese woman with a history of skin/soft-tissue infections and diabetes mellitus, presented with panniculitis. Initial treatment with β-lactam antibiotics did not result in clinical improvement. Methicillin-resistant ...
Nafziger Elizabeth E Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, - - 2014
Nuchal translucency (NT) is a hypo-echoic region of subcutaneous fluid accumulation in the posterior neck at the level of the cervical spine between the skin and soft tissues found at 10-14 weeks gestation. This ultrasound finding is important because increased NT measurements place the fetus at increased risk for chromosomal ...
Yao Wang W Department of Mechanical Engineering, Columbia University, New York, NY, - - 2014
The human cervix is an important mechanical barrier in pregnancy which must withstand the compressive and tensile forces generated from the growing fetus. Premature cervical shortening resulting from premature cervical remodeling and alterations of cervical material properties are known to increase a woman׳s risk of preterm birth (PTB). To understand ...
Amusquivar Encarnacíón E Faculties of Pharmacy and Medicine, Universidad San Pablo CEU, Ctra. Boadilla del Monte km 5.3, 28668, Madrid, - - 2014
Dietary trans-fatty acids (t-FA) during pregnancy have adverse effects on growth and development. To determine the effect of dietary t-FA during just the first half of pregnancy, rats were given a diet containing 8 % hydrogenated peanut oil and 2 % olive oil (PO) and compared to rats given a diet containing ...
Stasinopoulou Marianna M Laboratory of Animal Facilities, Centre of Experimental Surgery, Biomedical Research Foundation Academy of Athens, Athens, - - 2014
Researchers sometimes face difficulties in the diagnosis of pregnancy and assessment of embryonic development. Ultrasonography (US) is a non-invasive imaging method with minimal side effects on the subjects or operators. It provides real-time evaluation of the physiology of rapidly moving structures (i.e., heart) and facilitates evaluation of fetal tissue development. ...
Polyzou Electra N EN 3rd Department of Obstetrics and Gynecology, University of Athens, Medical School, Athens, - - 2014
Current knowledge on the participation of angiopoietin-2 (Ang-2) in the inflammatory process and on the importance of bacterial endotoxins (LPS) in the induction of preterm delivery (PTD) led us to investigate the role of Ang-2/LPS interplay in the pathogenesis of PTD. At a first stage, Ang-2 was measured at the ...
Bakkour Sonia S Blood Systems Research Institute; San Francisco, CA - - 2014
Although pregnancy-associated microchimerism is known to exist in humans, the clinical significance remains unclear. Fetal microchimerism has been documented in rhesus monkeys, but the trafficking and persistence of maternal cells in the monkey fetus and infant have not been fully explored. To investigate the frequency of maternal microchimerism in the ...
Ota Hajime H Department of Obstetrics and Gynecology, Hadano Red Cross Hospital, Kanagawa, - - 2014
A 23-year-old woman, gravida 1, para 1, was transferred to our hospital with acute lower abdominal pain and vital signs consistent with shock. Her urine concentration of human chorionic gonadotrophin was 8000 mIU/mL. Transvaginal ultrasound revealed an echo-free space with mosaic echo pattern in the right adnexal area and no ...
Todhunter K H KH School of Agriculture and Food Sciences, The University of Queensland, Gatton, Queensland, - - 2014
Pregnant mares were experimentally exposed to whole caterpillar or exoskeleton of the Processionary caterpillar (Ochrogaster lunifer) via gavage. Tissues were collected from resulting abortions and near or full-term pregnancies consisting of 13 aborted fetuses, 3 fetuses from treated euthanized mares, membranes of 5 foals, and organs from 3 foals. Three ...
Beriot Mathilde - - 2014
This paper describes the isolation and characterization of pregnancy-associated glycoproteins (PAG) from fetal cotyledonary tissue (FCT) and maternal caruncular tissue (MCT) collected from fallow deer (Dama dama) pregnant females. Proteins issued from FCT and MCT were submitted to affinity chromatographies by using Vicia villosa agarose (VVA) or anti-bovine PAG-2 (R#438) ...
Khan Nazoora N Department of Pathology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, - - 2014
Mature cystic teratomas are benign ovarian neoplasms which account for around 95% of all ovarian germ cell tumours and contain tissues derived from two or three embryonic germ layers. These tumours are frequently diagnosed in women of reproductive age group and can result in fetomaternal distress if concurrent pregnancy occurs. ...
Wester-Rosenlöf Lena L Department of Infection Medicine, Lund University, Lund, - - 2014
Preeclampsia (PE) is a serious pregnancy complication that manifests as hypertension and proteinuria after the 20(th) gestation week. Previously, fetal hemoglobin (HbF) has been identified as a plausible causative factor. Cell-free Hb and its degradation products are known to cause oxidative stress and tissue damage, typical of the PE placenta. ...
Lozoya Teresa T Hospital Universitario La Fe, Valencia, - - 2014
Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the potential role of this molecular hub in the pathogenesis of ectopic gestation. Seventeen patients suffering from tubal ...
Nikolaou Marinos M 0000-0001-9414-0634 Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, - - 2014
Necrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28 weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremity pain and high fever the last 72 hours. During ...
Chen Ling L Nanjing Maternal and Child Health Hospital of Nanjing Medical University, Nanjing, China; Institute of Pediatrics, Nanjing Medical University, Nanjing, - - 2014
This study assessed the growth trends and reference ranges of the ultrasound parameters, fetal abdominal subcutaneous tissue thickness (ASTT) and subscapular subcutaneous tissue thickness (SSTT), in the last two trimesters of normal pregnancy in a Chinese population. We recruited 744 healthy women with singleton pregnancies. The ASTT and SSTT were ...
Morelli M M Unit of Obstetrics and Gynaecology, Department of Experimental and Clinical Medicine, 'Magna Graecia' University-Catanzaro, - - 2013
The molecular aspects involved in human implantation include many elements that were first discovered due to their role in cancer cell metastasis. Periostin, a cell adhesion protein that allows the maintenance of cancer stem cells, may influence implantation. The objective of this experimental case-control study was to investigate tissue and ...
Staff A C AC Department of Obstetrics, Oslo University Hospital, Ullevål, Norway; Department of Gynaecology, Oslo University Hospital, Ullevål, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address: - - 2013
The decidua basalis is one of the frontiers between placenta and mother. Its spiral arteries ensure that the placenta and fetus have adequate access to the maternal circulation, without compromising maternal health. Normally this requires a tightly regulated collaboration between tissues of genetically different individuals. But like all frontiers it ...
von Holstein I C C IC BioArCh, Departments of Archaeology and Chemistry, University of York, Heslington, York, YO10 5DD, - - 2013
A variety of metabolic, dietary and climatic influences on isotopic variation have been established in mammalian hair. The relevance of these factors to collagen isotopic composition is unknown, but would be of great interest to zooarchaeological analyses of faunal skeletal tissue. The relationships between carbon (δ(13) C), nitrogen (δ(15) N), ...
Kasher-Meron Michal - - 2013
Abstract Objectives: Chemerin, a novel adipocytokine, has been implicated in major metabolic and inflammatory processes. Study aims were to determine whether circulating maternal chemerin concentration (1) differs between pregnant and non-pregnant women, (2) changes as a function of gestational age, and (3) correlates with maternal insulin resistance. In addition, we ...
Ateka-Barrutia Oier - - 2013
Connective tissue diseases (CTD) include a variety of chronic multisystem disorders with a high percentage of autoimmune conditions. Many of these conditions affect women of childbearing age and, therefore, pregnancy poses an important challenge for doctors looking after such women. Knowledge of medication safety, the effect of pregnancy on such ...
Chen Chih-Ping CP Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Department of Biotechnology, Asia University, Taichung, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; Institute of Clinical and Community Health Nursing, National Yang-Ming University, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address: - - 2013
To present female pseudohermaphroditism in a prenatally diagnosed cloacal malformation. A 29-year-old, primigravid woman referred for counseling at 17 weeks of gestation because of oligohydramnios and an intra-abdominal cyst in the fetus. The woman was not exposed to any virilizing agent during this pregnancy. She did not undergo any assisted ...
Pérez-Medina Tirso - - 2013
To describe the feasibility of office hysteroscopy in patients with pregnancy-related problems such as retained trophoblastic tissue, persistent molar tissue, pregnancy with in situ IUD, isthmocele, embryoscopy and osseous metaplasia. Retrospective cohort chart review on the utility of hysteroscopy in 273 patients with pregnancy-related problems. Classification: Canadian Task Classification Force ...
Gao Ya - - 2013
Non-invasive prenatal testing (NIPT) at 13(+2) week of a 42-years-old mother with combined risk of Down syndrome 1/70 revealed high risk of trisomy X (XXX). Amniocentesis performed after positive ultrasound scan at 16(th) week revealed karyotype 48,XXX, +18 , indicating a false negative NIPT result of trisomy 18(T18). Further karyotyping ...
Mundangepfupfu Tichaendepi - - 2013
Hydatidiform mole (molar pregnancy) is a benign tumor of placental trophoblastic cells, which release human chorionic gonadotropin (hCG). Several case reports have described complete hydatidiform moles with false-negative urine qualitative hCG tests. These negative pregnancy tests have been attributed to the hook effect. We report an unusual presentation of a ...
Kane Andrew D AD Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, United - - 2013
Fetal brain hypoxic injury remains a concern in high-risk delivery. There is significant clinical interest in agents that may diminish neuronal damage during birth asphyxia, such as in allopurinol, an inhibitor of the prooxidant enzyme xanthine oxidase. Here, we established in a rodent model the capacity of allopurinol to be ...
Anderson Cindy M - - 2013
Background: Preeclampsia contributes significantly to pregnancy-associated morbidity and mortality as well as future risk of cardiovascular disease in mother and offspring, and preeclampsia in offspring. The lack of reliable methods for early detection limits the opportunities for prevention, diagnosis, and timely treatment.Purpose: The purpose of this study was to explore ...
Hayes Emily K - - 2013
Maternal obesity is associated with an increased risk of a number of pregnancy complications, including fetal demise, which may be linked to impaired placental development as a result of altered trophoblast invasion and vessel remodeling. Therefore, we examined these parameters in pregnant rats fed a control (normal weight) or high ...
Avi Harlev - - 2013
Abstract OBJECTIVE: To examine if, as in obesity, pregnancies complicated by gestational diabetes mellitus (GDM) exhibit increased macrophage infiltration and activated MAP-kinases in omental adipose tissue. Paired omental (OM) and abdominal subcutaneous (SC) fat samples were collected from 11 GDM and 20 normal pregnancies during cesarean delivery. Tissues were stained ...
Nanovskaya Tatiana N TN Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, - - 2013
The objective of the study was to determine the bidirectional transfer of pravastatin across the dually perfused term human placental lobule and its distribution between the tissue and maternal and fetal circuits. The transfer of pravastatin was determined in the maternal-to-fetal (n = 11) and fetal-to-maternal (n = 10) directions. Pravastatin was ...
Zajicek Michal - - 2013
To evaluate fetal secondary palate in fetuses at 12 to 16 weeks' gestation by three-dimensional ultrasound (3DUS). Between June 2006 and July 2008, volumes of palate were prospectively acquired in fetuses at gestational age of 12-16 weeks. Acquisition was performed when the fetus was facing the transducer with head extended at an ...
Kwon Eun Ji - - 2013
: Polymorphic eruption of pregnancy (PEP), formerly known as pruritic urticarial papules and plaques of pregnancy, is a dermatosis of pregnancy that must be distinguished from pemphigoid gestationis (PG). Although this differential diagnosis may be possible on routine histology, an additional biopsy for direct immunofluorescence (DIF) is often needed. Recent ...
Torricelli Michela - - 2013
Abstract Objective: The aim of this study was to investigate the rate of the different Histological Chorioamnionitis (HCA) grade in relation to the gestational age in term and preterm delivery. Methods: 392 women with singleton pregnancy with spontaneous onset of labor either prematurely or at term, with histologic diagnosis of ...
Kivelio A - - 2013
Iatrogenic preterm prelabour rupture of fetal membranes (iPPROM) remains the main complication after invasive interventions into the intrauterine cavity. The aim of this study was to evaluate the sealing capability and tissue interaction of mussel-mimetic tissue adhesive (mussel glue) in comparison to fibrin glue on punctured fetal membranes in vivo. ...
Sakamoto Mineshi - - 2013
The role of the placenta was assessed by comparing the profiles of methylmercury (MeHg), inorganic mercury (I-Hg), lead (Pb), cadmium (Cd), selenium (Se), zinc (Zn), and copper (Cu) in freeze-dried chorionic tissue of the placenta and umbilical cord tissue. The significance of the placenta and cord tissue as predictors of ...
George R B RB Department of Women's and Obstetric Anesthesia, IWK Health Centre, Halifax, Nova Scotia, Canada; Department of Anesthesiology, Pain Management, and Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: - - 2013
The microcirculation is responsible for distribution of blood within tissues, delivery of oxygen and other nutrients, and regulation of blood pressure. The objective of this study was to compare the sublingual microcirculation of pregnant participants to that of comparable non-pregnant volunteers. Two groups of participants were recruited: a group of ...
Stern C J - - 2013
Ovarian tissue cryopreservation and transplantation is a form of fertility preservation offered to young women at high risk of losing ovarian function after cancer treatment. While there have been successful births resulting from orthotopic site grafts, we report the first case of an ongoing pregnancy from a heterotopic graft in ...
Taweevisit Mana - - 2013
Abstract The distribution of lipid in the fetal adrenal cortex is reported to correlate with the duration of hypoxia and degree of fetal stress. The original studies were based on Oil Red O staining, requiring frozen tissue that is often not available. To investigate the reliability of these observations, the ...
Garrod A - - 2013
We assessed whether placental morphology is affected by placental storage before fixation. Fresh tissue from uncomplicated pregnancies (n = 10) was fixed immediately and further samples were stored dry, in PBS or culture medium for 24, 48 or 72 h at 4 °C. Placental morphology quantified using image analysis software found no difference in ...
Sivakumar K - - 2013
Context and Objective:Obesity in pregnancy is associated with increased risks of obesity in the offspring. We investigated the relationship between obesity in pregnancy and circulating maternal and fetal levels of adipose tissue-derived factors adipsin and acylation stimulating protein (ASP) in lean and obese mothers.Design:Paired peripheral and cord blood samples were ...
Osol George - - 2013
Remodeling of the maternal uterine vasculature during pregnancy is a unique cardiovascular process that occurs in the adult and results in significant structural and functional changes in large and small arteries and veins, and in the creation of the placenta - a new fetomaternal vascular organ. This expansive, hypertrophic process ...
Sinai Talaulikar Vikram - - 2013
The human embryo-maternal interface in the first trimester of pregnancy is an area of extensive tissue remodeling. Because collagen is the most abundant constituent of the extracellular matrix of the placental bed, successful invasion must involve its rapid turnover. We compared the nature and distribution of collagen fibrils in decidua ...
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