Search Results
Results 251 - 300 of 1304
< 1 2 3 4 5 6 7 8 9 10 11 >
Gray Stephen P - - 2008
Maternal alcohol consumption during pregnancy can affect fetal development, but little is known about the effects on the developing kidney. Our objectives were to determine the effects of repeated ethanol exposure during the latter half of gestation on glomerular (nephron) number and expression of key genes involved in renal development ...
Aliyu Muktar H - - 2008
The purpose of this study is to investigate the association between maternal alcohol intake in pregnancy and the occurrence of early stillbirth using a retrospective cohort analysis of singleton births in Missouri that occurred in the period 1989 through 1997 (N=655,979). We used Cox proportional hazards regression to generate adjusted ...
Pueta Mariana - - 2008
Ethanol experiences, during late gestation as well as during nursing, modify the behavioral dynamics of the dam/pup dyad, and leads to heightened ethanol intake in the offspring. This study focuses on: a) behavioral and metabolic changes in intoxicated dams with previous exposure to ethanol during pregnancy and b) infantile consumption ...
Strain J J - - 2008
Fish consumption during gestation can provide the fetus with long-chain polyunsaturated fatty acids (LCPUFA) and other nutrients essential for growth and development of the brain. However, fish consumption also exposes the fetus to the neurotoxicant, methyl mercury (MeHg). We studied the association between these fetal exposures and early child development ...
Mayock Dennis E - - 2008
Fetal alcohol syndrome is a leading cause of mental retardation, but mechanisms of alcohol-associated brain damage remain elusive. Chronic alcohol exposure attenuates fetal and neonatal hypoxic cerebral vasodilation in sheep. We therefore hypothesized that alcohol could alter development of cerebrovascular responses to adenosine, a putative mediator of hypoxic cerebral vasodilation. ...
Hotham Elizabeth - - 2008
BACKGROUND: Australian substance use data do not demonstrate pregnancy-related changes or distinguish between pregnant and lactating women. AIMS: To determine such changes by antenatal patients at two South Australian public hospitals accounting for 35% of the state's births. METHODS: In 2005-2006, all first visit antenatal women at the two hospitals ...
Elliott Elizabeth J - - 2008
New draft alcohol guidelines for Australia state that, for pregnant women and women planning pregnancy, 'no drinking is the safest option'. One of the best known adverse effects of alcohol exposure on the fetus is the fetal alcohol syndrome. Others include alcohol-related birth defects, alcohol-related neurodevelopmental disorders and increased risks ...
Schneider Miriam - - 2008
During puberty, neuronal maturation of the brain, which began during perinatal development, is completed such that the behavioral potential of the adult organism can be fully achieved. These maturational events and processes of reorganization are needed for the occurrence of adult behavioral performance but simultaneously render the organism highly susceptible ...
Bailey Beth A - - 2008
Pregnancy alcohol consumption has been linked to poor birth outcomes and long-term developmental problems. Despite this, a significant number of women drink during pregnancy. Although most prenatal care providers are asking women about alcohol use, validated screening tools are infrequently employed. Research has demonstrated that currently available screening methods and ...
Coyne Katherine L - - 2008
BACKGROUND: Fetal alcohol syndrome (FAS) has been identified as a major cause of impairment to normal physical and intellectual development among Indigenous children in Far North Queensland; however, little is known of the pregnancy characteristics of mothers of those children diagnosed with FAS or of interventions that might assist in ...
Kuykendall Jim R - - 2009
DNA-protein cross-links (DPXs) in fish erythrocytes represent a potential biomarker for exposure to metal cations, such as hexavalent chromium (Cr[VI]) and divalent nickel (Ni[II]). Species-specific sensitivities to DPX formation were studied by coexposure of juvenile specimens of rainbow trout, hybrid bluegill, and channel catfish to waterborne metals, such as Cr(VI) ...
Lee Young Joo - - 2008
Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels ...
Kvigne Valborg L - - 2008
INTRODUCTION: The purpose of the study was to compare three sequential pregnancies of American Indian women who have children with FAS or children with incomplete FAS with women who did not have children with FAS. METHODS: Two retrospective case-control studies were conducted of Northern Plains American Indian children with fetal ...
Gaworecki Kristen M - - 2008
Environmental contaminants, including pharmaceuticals, can alter behavior and possibly impact population and community structures. One important behavior that could be impacted is the ability to capture prey. We hypothesized that sublethal fluoxetine exposure may lead to feeding behavior abnormalities in hybrid striped bass (Morone saxatilis x M. chrysops). Fluoxetine is ...
MacLehose Richard F - - 2008
BACKGROUND: Laboratory evidence suggests tap water disinfection by-products (DBPs) could have an effect very early in pregnancy, typically before clinical detectability. Undetected early losses would be expected to increase the reported number of cycles to clinical pregnancy. METHODS: We investigated the association between specific DBPs (trihalomethanes, haloacetic acids, brominated-trihalomethanes, brominated-haloacetic ...
Nowakowski Richard S - - 2008
Widespread radiation is a threat unique to the modern world. A recent report reveals that sub-clinical damage to human foetuses between 8 and 25 weeks of gestation can result in cognitive deficits still manifest 16-18 years after birth. These previously unrecognised, long-term effects are apparently produced by a relatively short ...
Gul Ahmet - - 2008
OBJECTIVE: We aimed to evaluate perinatal outcome of seven pregnancies with twin reserve arterial perfusion sequence. MATERIALS AND METHODS: The study group included seven cases of acardiac twins. Out of seven acardiac twins, two cases were in follow-up without any interventions. We performed four alcohol ablation and one bipolar coagulation. ...
Livingston Michael - - 2008
AIMS: A large number of studies have found links between alcohol outlet densities and assault rates in local areas. This study tests a variety of specifications of this link, focusing in particular on the possibility of a non-linear relationship. DESIGN: Cross-sectional data on police-recorded assaults during high alcohol hours, liquor ...
Garcia-Algar Oscar - - 2008
The prevalence of gestational ethanol exposure and subsequent fetal exposure has been assessed in a cohort of mother-infant dyads in a Mediterranean city (Barcelona, Spain) by meconium analysis of fatty acid ethyl esters (FAEEs) after showing in this population a high prevalence of meconium opiates (8.7%), cocaine (4.4%), and cannabis ...
Datta Susmita - - 2008
Fetal Alcohol Syndrome (FAS), a severe consequence of the Fetal Alcohol Spectrum Disorders, is associated with craniofacial defects, mental retardation, and stunted growth. Previous studies in C57BL/6J and C57BL/6N mice provide evidence that alcohol-induced pathogenesis follows early changes in gene expression within specific molecular pathways in the embryonic headfold. Whereas ...
de Chazeron Ingrid - - 2008
BACKGROUND: Although it is well known that France has a cultural history of alcohol use, no recent French data on alcohol consumption during pregnancy in a large sample are available. METHODS: To determine the alcohol consumption patterns among pregnant women in France, we analyzed data from a 1-year multicenter self-survey. ...
Nettleton Rosemary T - - 2008
This study uses a neonatal guinea pig model to compare the effects of in utero methadone or morphine exposure upon breathing control. We hypothesize that in utero methadone exposure will result in similar respiratory disturbances to those seen in morphine exposed neonates, but that the onset will be slower and ...
May Philip A - - 2008
OBJECTIVES: This is a third exploration of risk factors for the two most severe forms of fetal alcohol spectrum disorders (FASD), fetal alcohol syndrome (FAS) and Partial FAS (PFAS), in a South African community with the highest reported prevalence of FAS in the world. METHODS: In a case control design, ...
Ethen Mary K - - 2009
OBJECTIVES: To determine the prevalence, patterns, and predictors of alcohol consumption prior to and during various intervals of pregnancy in the U.S. METHODS: Alcohol-related, pregnancy-related, and demographic data were derived from computer-assisted telephone interviews with 4,088 randomly selected control mothers from the National Birth Defects Prevention Study who delivered live ...
Strandberg-Larsen Katrine - - 2008
OBJECTIVE: To examine whether the frequency and timing of binge drinking episodes (intake of five or more drinks on one occasion) during the first 16 weeks of pregnancy increase the risk of fetal death. METHODS: The study is based upon data from 89,201 women who were enrolled in the Danish ...
Chan Sunny Sun-Kin - - 2008
Magnolia officinalis is a commonly used traditional Chinese medicine for treating gastrointestinal disorders. HPLC quantification analysis revealed that magnolol and honokiol were the most abundant constituents of M. officinalis extracts, with their contents in the ethanol extract being the highest, the water extract the least and the 50 % ethanol ...
Cuzon Verginia C - - 2008
Consumption of alcohol (ethanol) during pregnancy can lead to developmental defects in the offspring, the most devastating being the constellation of symptoms collectively referred to as fetal alcohol syndrome (FAS). In the brain, a hallmark of FAS is abnormal cerebral cortical morphology consistent with insult during corticogenesis. Here, we report ...
Smith George Davey - - 2008
The influence of factors acting during the intrauterine period on health outcomes of offspring is of considerable research and public health interest. There are, however, methodological challenges in establishing robust causal links, because exposures often act many decades before outcomes of interest, may act before it is evident that women ...
Littner Yoav - - 2008
Specific fatty acid ethyl esters (FAEE) in meconium of newborns have been shown to correlate with maternal ethanol exposure. An animal model is needed to assess the validity of this biomarker. We hypothesized that the pregnant/fetal sheep is a feasible animal model for validating FAEE as a biomarker of prenatal ...
Peiris-John Roshini J - - 2008
Despite their widespread and longstanding use for the public good, organophosphate (OP) pesticides have led to many adverse effects on human health. Environmental exposure to OPs and adverse reproductive outcomes in men and women working on or living near farms are increasingly reported worldwide. The aim of the current review ...
Abate Paula - - 2008
Near-term fetuses of different mammalian species, including humans, exhibit functional sensory and learning capabilities. The neurobiological literature indicates that the unborn organism processes sensory stimuli present in the amniotic fluid, retains this information for considerable amounts of time, and is also capable of associating such stimuli with biologically relevant events. ...
Lenkowski Jenny R - - 2008
Exposure to anthropogenic chemicals during development can disrupt the morphogenesis of organ systems. Use of the herbicide atrazine has been debated in recent years because of its implicated, but poorly characterized, effects on vertebrates. Previous studies primarily examined the effects of atrazine exposure during metamorphosis or early developmental stages of ...
Rocha E Silva Ingrid Ramos - - 2008
OBJECTIVE: To examine whether there is an association between fetal and/or placental weight and exposure to ambient levels of air pollution in mice. DESIGN: Chronic experiments on mice that were exposed to polluted vs. clean air. SETTING: Environmental exposure to atmospheric pollution. ANIMAL(S): Female Swiss mice (n = 70) were ...
Kvigne Valborg L - - 2008
INTRODUCTION: Characteristics of Northern Plains American Indian maternal grandmothers who had grandchildren with fetal alcohol syndrome (FAS) or incomplete FAS are described to more effectively prevent fetal FAS and alcohol use during pregnancy. METHODS: Study 1 had 27 maternal grandmothers who had grandchildren with FAS and Study 2 had 18 ...
Gijsen Violette - - 2008
A recent study published from the University College London suggests that children of women who were light drinkers during pregnancy demonstrate better cognitive outcome at three years of age when compared to children of abstinent women based on data from the UK Millennium Cohort Study. Unfortunately, methodological pitfalls and limited ...
Al-Ardhi Fatma Mohammed Mahfoodh - - 2008
The benefits of fish consumption have been known to be the prevention of certain heart disease, neurological disorders and a very important role in fetal brain development. However there has been, in the past, certain doubts on whether fish should be classified as a beneficial meat source as part of ...
Huang Yi-Chen - - 2008
One seven-year-old aboriginal boy visited our outpatient department for survey of study difficulty. The physical examination revealed microcephaly, broad depressed nasal bridge, thin upper lip, smooth philtrum, epicanthal folds and clinodactyly. He also had mild mental retardation and abnormal findings on brain MRI. His mother had confirmed daily alcoholic consumption ...
Strandberg-Larsen Katrine - - 2008
BACKGROUND: Consumption of high doses of alcohol on a single occasion (binge drinking) may harm the developing foetus and pregnant women are advised to avoid binge drinking while pregnant. We present characteristics of Danish women who binge drank in the pre-and post recognised part of their pregnancy. METHODS: During the ...
Nilsen Per - - 2008
OBJECTIVE: To investigate alcohol intake during pregnancy among women, to assess health cares providers' advice to the women and the relative importance of different factors on changes in the women's drinking. DESIGN: Questionnaire study. SETTING: Linkoping, Sweden. POPULATION: A total number of 1,533 women registered at a maternity health care ...
Yamamoto Yuko - - 2008
BACKGROUND: In order to clarify the alcohol consumption status of pregnant women in Japan and the characteristics of pregnant women who abstained from alcohol after their pregnancy had been confirmed, a nationwide questionnaire-based study of alcohol consumption behavior was performed. We also examined the factors associated with alcohol consumption during ...
Savitz David A - - 2008
BACKGROUND: Coffee and caffeine have been inconsistently found to be associated with increased risk of clinical miscarriage-a potentially important association given the high prevalence of exposure. METHODS: Women were recruited before or early in pregnancy and interviewed regarding sources of caffeine, including assessment of changes over the perinatal period. We ...
Patel Prakash K - - 2008
To study the profile of reported fetal death cases and describe the circumstances under which these deaths occurred. This is a retrospective case series study of 154 fetal deaths that occurred in the entire Dhahira region health institutions during a 5 year period (January 2000 and December 2004). The fetal ...
Bobo Janet Kay - - 2007
To prevent fetal alcohol syndrome, some social drinkers who may become pregnant need more than a brief caution, but they can be difficult to detect in clinical settings. National Longitudinal Survey of Youth data from 754 women who completed up to four alcohol history interviews during their college-age years (18-21), ...
Górny RafaƂ L - - 2007
The effects of microwave radiation on viability of fungal and actinomycetal spores growing on agar (medium optimal for growth) as well as on wooden panel and drywall (common building construction/finishing materials) were studied. All materials were incubated at high (97-99%) and low (32-33%) relative humidity to mimic "wet" and "dry" ...
Campero Melina - - 2007
Biomarkers are widely used to assess pesticide stress, but their ecological relevance and exposure time dependent sensitivity is still heavily debated. We studied both aspects in larvae of the damselfly Coenagrion puella, comparing the impact of low doses of atrazine, carbaryl, and endosulfan on two key biomarkers (acetylcholinesterase [AChE] activity ...
Henderson Jane - - 2007
The effects of binge-drinking during pregnancy on the fetus and child have been an increasing concern for clinicians and policy-makers. This study reviews the available evidence from human observational studies. Systematic review of observational studies. Population: Pregnant women or women who are trying to become pregnant. A computerised search strategy ...
Unal Dilek - - 2008
Physcia semipinnata was exposed to UV-A (352nm) and visible light (210, 800 and 2000mW/cm2) for 30min, 1, 2, 24, and 48h to seek the alterations in the PSII photosynthetic quantum yield, in response to radiation. Chlorophyll a fluorescence did not influence exposure to light, 210, 800 and 2000mW/cm2. Significant alterations ...
Sugawara Norio - - 2008
Methylmercury (MeHg) and polychlorinated biphenyls (PCBs) are environmental pollutants that cause neurobehavioral deficits in humans. Because exposures to MeHg and PCBs occur through fish consumption, it is necessary to clarify the effects of the interaction of the two pollutants. Therefore, we investigated the effects of perinatal exposure to MeHg and ...
Micklesfield L K - - 2007
BACKGROUND: The influence of early life factors on the bone mineral density of children has been identified, however the contribution of these determinants may vary. AIM: The study investigated determinants of bone mineral content (BMC) in South African children of mixed ancestral origin. SUBJECTS AND METHODS: Early life data including ...
D'Onofrio Brian M - - 2007
CONTEXT: Existing research on the neurobehavioral consequences of prenatal alcohol exposure (PAE) has not adequately accounted for genetic and environmental confounds. OBJECTIVE: To examine the association between PAE and offspring externalizing problems in a large representative sample of families in the United States using measured covariates and a quasi-experimental design ...
< 1 2 3 4 5 6 7 8 9 10 11 >