Search Results
Results 201 - 250 of 1304
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Holmqvist Marika - - 2010
OBJECTIVE: to evaluate how much education midwives in Sweden have undertaken to help them assess alcohol intake during pregnancy, and what tools they use to identify women who may be at risk of drinking during pregnancy. DESIGN: a national survey was conducted in March 2006, using a questionnaire constructed by ...
Bowen Scott E - - 2009
Toluene is a commonly abused organic solvent. Inhalant abusers are increasingly women in their prime childbearing years. Children born to mothers who abused solvents during pregnancy may exhibit characteristics of a "fetal solvent syndrome" which may include dysmorphic features. This study examined the teratological effects of an abuse pattern of ...
Summers Brooke L - - 2009
BACKGROUND: We have previously demonstrated that ethanol teratogenicity is associated with metallothionein-induced fetal zinc (Zn) deficiency, and that maternal subcutaneous Zn treatment given with ethanol in early pregnancy prevents fetal abnormalities and spatial memory impairments in mice. Here we investigated whether dietary Zn supplementation throughout pregnancy can also prevent ethanol-related ...
Chiodo Lisa M - - 2009
BACKGROUND: Fetal Alcohol Spectrum Disorders (FASDs), including Fetal Alcohol Syndrome, continue to be high-incidence developmental disorders. Detection of patterns of maternal drinking that place fetuses at risk for these disorders is critical to diagnosis, treatment, and prevention, but is challenging and often insufficient during pregnancy. Various screens and measures have ...
de Mos M - - 2009
OBJECTIVE: Since complex regional pain syndrome (CRPS) shows a clear female predominance, we investigated the association between the cumulative as well as current exposure to estrogens, and CRPS. METHODS: A population-based case-control study was conducted in the Integrated Primary Care Information (IPCI) project in the Netherlands. Cases were identified from ...
Dwarkanath Pratibha - - 2009
In recent years there is growing interest on the role of long chain omega-3 polyunsaturated fatty acids (omega-3 LC-PUFA) in pregnancy and the growth and development of the offspring. We aim to characterize and provide baseline data on the intake of LCPUFA (omega-3 and omega-6) in a prospective cohort of ...
Gareri Joey - - 2009
BACKGROUND: Mediators of susceptibility to alcohol-related toxicity in the prenatal environment are relatively unknown. The placenta has been proposed as a potential source of variability in the fetal environment, primarily through its significant metabolic capabilities. Meconium is a toxicological matrix unique to the developing fetus that offers an opportunity to ...
Reynolds Ben C - - 2009
Although the adverse effects of cocaine use in pregnancy are well recognised, we believe this case highlights the importance of considering the route of administration, and suggests the possibility of multifocal damage relating to intravenous use. A Caucasian female baby of 29-weeks' gestation was spontaneously delivered and subsequently developed multi-organ ...
Pichini Simona - - 2009
BACKGROUND: In recent years, fatty acid ethyl esters (FAEEs) in meconium emerged as reliable, direct biological markers for establishing gestational ethanol exposure. Among the minor nonoxidative products of ethanol metabolism, there are ethyl glucuronide (EtG) and ethyl sulfate (EtS). OBJECTIVES: The aim of the study was to analyse meconium specimens ...
Pola?ska Kinga - - 2009
OBJECTIVES: Exposures during prenatal period have implications for pregnancy outcome as well as for children's health, morbidity and mortality. Prospective cohort study design allows for the identification of exposures that may influence pregnancy outcome and children's health, verification of such exposures by biomarker measurements and notification of any changes in ...
Reynolds Ben C - - 2009
Although the adverse effects of cocaine use in pregnancy are well recognised, we believe this case highlights the importance of considering the route of administration, and suggests the possibility of multifocal damage relating to intravenous use. A Caucasian female baby of 29-weeks' gestation was spontaneously delivered and subsequently developed multi-organ ...
Wyszynski Diego F - - 2009
Pregnancy exposure registries systematically evaluate pregnancies and outcomes exposed to a medicinal compound or device during the gestational period. Historically, such programs partner an academic institution with one or more pharmaceutical companies or are run solely by a pharmaceutical company. However, other examples abound. This article describes what a pregnancy ...
Armstrong Mary Anne - - 2009
This clinical trial compared two brief alcohol use interventions in prenatal clinics: Early Start (ES), a substance-abuse screening and treatment program integrated with prenatal care focused on abstention (n=298), and Early Start Plus (ESP), adding a computerized drink-size assessment tool and intervention focused on drinking less (n=266). Controls were untreated ...
Raymond Neil - - 2009
There is uncertainty as to whether there is a safe threshold for drinking alcohol during pregnancy. We explored pregnant women's attitudes towards drinking alcohol in pregnancy and their attitudes towards sources of information about drinking in pregnancy following recent changes in UK government guidance. A qualitative study involving individual, semi-structured ...
Tsukahara Shinji - - 2009
The goal of our study was to determine if toluene affected the synthesis and secretion of testosterone in fetal rats. Dams were exposed to atmospheres that contained 0.09 ppm, 0.9 ppm or 9 ppm of toluene for 90 min/day from gestational days (GDs) 14.5 to 18.5 via nasal inhalation. Fetal ...
Ratnapalan Savithiri - - 2008
Exposure to ionizing radiation can be a source of anxiety for many pregnant women and their health care providers. An awareness of the radiation doses delivered by different techniques and the acceptable exposure thresholds can help both patients and practitioners. We describe exposure to radiodiagnostic procedures during pregnancy and suggest ...
Sen Jaydip - - 2008
Twelve districts of the state of West Bengal, India are affected by arsenic (As) and millions of individuals are consuming As-contaminated groundwater. The probable adverse effects of As on pregnancy outcome (stillbirth and miscarriage) are yet to be properly studied. The present investigation is an attempt to understand the effects ...
Mortimer Kathleen - - 2008
Observations on the association between exposure to common outdoor air pollutants and allergic sensitization have not been consistent. Little research has been done on the effects of prenatal exposure or the effect among asthmatics. The association between prenatal and early-life exposures and outdoor air pollutants with allergic sensitization was examined ...
Alati Rosa R School of Population Health, University of Queensland, Herston, Queensland, 4006 Australia. - - 2008
This study aims to test the hypothesis that moderate maternal alcohol and tobacco use in pregnancy is associated with intelligent quotient (IQ) scores in childhood through intrauterine mechanisms. We conducted parental-offspring comparisons between the associations of tobacco and alcohol consumption with child's IQ in the Avon Longitudinal Study of Parents ...
Fiore Marco - - 2009
Ethanol exposure during pregnancy is one of the major causes of mental retardation in western countries by inducing fetal-alcohol-like-syndromes. Red wine is known to contain ethanol but also compounds with putative antioxidant properties. It has also been shown that nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) are ...
Grant Therese M - - 2009
OBJECTIVE: We examined trends in rates of self-reported pregnancy alcohol use among women in western Washington. STUDY DESIGN: Between 1989 and 2004, we conducted 3 studies in western Washington State on problems that are associated with maternal prenatal alcohol or drug abuse (n = 12,526). To determine study eligibility, we ...
Gospe Sidney M SM - - 2009
While there is evidence that human perinatal exposure to environmental tobacco smoke (ETS) can result in an increased risk of respiratory disorders and sudden infant death syndrome, evidence linking ETS exposure to neurodevelopmental handicaps is suggestive but less compelling. We previously noted that postnatal ETS exposure, rather than prenatal exposure, ...
Suh Young Ju - - 2009
PURPOSE: We conducted this study to determine if the preterm risks due to PM(10) exposure vary with the exposure periods during pregnancy. This study was also conducted to estimate the different effects of PM(10) exposure on preterm birth by exposure periods using the extended Cox model with PM(10) exposure as ...
Hubicka Beata - - 2008
The prevalence and types of crime offences, as well as predictors of relapse, among drivers suspected of driving under influence (DUI) were investigated. A total of 1830 Swedish DUI drivers responded to the Alcohol Use Disorders Identification Test--AUDIT. Information about previous DUI offences, other traffic offences along with other types ...
Roberts Susan Sinclair - - 2008
Ribavirin, used in combination with an interferon, is used for the treatment of chronic hepatitis C. Ribavirin is a Federal Drug Administration Pregnancy Category X product, indicating that its use is contraindicated in women who are pregnant. The package insert also states that ribavirin is contraindicated in men whose partners ...
Zammit Sonia L - - 2008
OBJECTIVE: This study had two aims: (1) to examine pregnant women's alcohol consumption across time from prepregnancy until childbirth and (2) to explore whether prepregnancy drinking and intention to drink predict prenatal alcohol consumption while controlling for relevant demographic variables. METHODS: At 17-21 weeks, 248 pregnant women completed questions about ...
Yokota Satoshi - - 2009
Diesel exhaust (DE) is composed of particles and gaseous compounds. It has been reported that DE causes pulmonary and cardiovascular disease. We have previously reported that fetal exposure to DE had deleterious effects to the reproductive system of mice offspring. However, there is still little known about the effects of ...
Spohr Hans-Ludwig - - 2008
The present review describes the different variants of Fetal Alcohol Spectrum Disorders (FASD) as a consequence of maternal alcohol abuse during pregnancy. According to international findings, some 3000 to 4000 affected newborns may be expected annually in Germany. Detection of these individuals in clinical practice is insufficient. Selective review of ...
Torres-Sanchez Luisa - - 2008
Anogenital distance (AGD) at birth is regarded as a useful measurement that reflects the prenatal androgenic status in rodents. However, the impact of xenoantiandrogens on human development is largely unknown. The aim of this study was to evaluate the potential antiandrogenic impact of prenatal DDT metabolites (p,p'-DDE and p,p'-DDT) exposure ...
Sharpe Tanya T - - 2008
OBJECTIVES: Poor women of childbearing age who use crack, cocaine, marijuana, and heroin may be at risk for having an alcohol-exposed pregnancy because of concurrent alcohol use. Women who use illicit drugs may not know the harmful effects of fetal alcohol exposure. Fetal alcohol exposure is a leading cause of ...
Nicolaïdis Stylianos - - 2008
Epigenetic influences on the fetus's genotype have been shown to occur during intrauterine life. Experimentally imposed extracellular dehydration in pregnant rats (a model for human hyponatremia caused by gravidic vomiting) brings about a dramatic enhancement of salt appetite not only in the dam, but also in offspring when they reach ...
Hughes Suzanne C - - 2009
OBJECTIVE: This study compared pregnant Latinas' report of alcohol use for the 3-month period before pregnancy recognition with two different methods of data collection, in an attempt to identify opportunities for improved screening. METHODS: Data were collected for 53 pregnant Latinas who have ever drunk alcohol and who were receiving ...
Tenkku Leigh E - - 2009
OBJECTIVE: The purpose of this study was to investigate the likelihood that women of different racial and ethnic groups would reduce their alcohol consumption during pregnancy. METHODS: Data came from 22 states participating in the Pregnancy Risk Assessment Monitoring System from 2001 to 2005. After stratifying the sample by preconception ...
Ettinger Adrienne S - - 2009
Prenatal lead exposure is associated with deficits in fetal growth and neurodevelopment. Calcium supplementation may attenuate fetal exposure by inhibiting mobilization of maternal bone lead and/or intestinal absorption of ingested lead. Our goal was to evaluate the effect of 1,200 mg dietary calcium supplementation on maternal blood lead levels during ...
Collier Alex - - 2008
We observed a slight drop in the growth of Xenopus laevis and Pseudacris triseriata larvae following acute exposure (24-48 h) during egg development to three concentrations of TCDD (0.3, 3.0, 30.0 mug/l). Our exposure protocol was modeled on a previous investigation that was designed to mimic the effects of maternal ...
Stillerman Karen Perry - - 2008
To better understand the science linking environmental contaminants exposures with adverse pregnancy outcomes, we reviewed the relevant epidemiologic literature. We searched PubMed (primarily 1995-2006) using the key word combinations for select environmental exposures and pregnancy outcomes. Environmental tobacco smoke is a risk factor for reduced birth weight and preterm delivery. ...
McMurray M S - - 2008
Gestational cocaine treatment results in significantly increased maternal aggression towards an intruder by postpartum day six, while acute postpartum treatment dose dependently decreases maternal aggressive (MA) behavior. Both increased and decreased aggression in the cocaine-treated dams are correlated with either decreased or increased levels of oxytocin in the amygdala, respectively. ...
Ramlau-Hansen C H - - 2008
BACKGROUND: A few studies have investigated the association between male caffeine consumption in adult life and semen quality with conflicting results, but so far no studies have explored the effect of prenatal coffee exposure. We studied the association between prenatal coffee and current caffeine exposure and semen quality and levels ...
Signore Caroline - - 2008
The precise pathway by which alcohol causes the characteristic features of fetal alcohol spectrum disorders is unknown. Proposed mechanisms for fetal injury from maternal alcohol use include cellular damage from oxidative stress and impaired fetal oxygenation related to maternal systemic vasoconstriction. Our objective was to compare the levels of urinary ...
Williams Megan K - - 2008
Widespread residential pesticide use throughout the United States has resulted in ubiquitous, low-level pesticide exposure. The mix of active pesticide ingredients is changing in response to 2000-2001 regulations restricting use of the organophosphorus insecticides chlorpyrifos and diazinon. We aimed to determine the impact of U.S. Environmental Protection Agency regulations on ...
Inoue Osamu - - 2008
This study was initiated to evaluate o-cresol and benzylmercapturic acid in urine in comparison with other biomarkers, as tools to estimate the intensity of occupational exposure to toluene at low levels. In total, 108 solvent exposed workers (engaged in tape production) and 17 non-exposed controls (all men) participated in the ...
Ege Markus Johannes - - 2008
BACKGROUND: Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school age. OBJECTIVE: We sought to evaluate the effects of maternal exposure to animal sheds and other farm-related exposures during pregnancy on cord blood IgE ...
Ang Ghee Soon - - 2008
Mycophenolate mofetil (MMF) is an immunosuppressive agent that has now been recognized as teratogenic in humans. A pattern of malformations from in utero exposure to MMF has recently been described, and includes cleft lip and palate, microtia and atresia of the external auditory canal. We present a nulliparous mother who ...
Plichart Matthieu - - 2008
Parental smoking and maternal alcohol and caffeinated beverage consumption are prevalent exposures which may play a role, either directly or through their influence on metabolism, in the aetiology of childhood malignant central nervous system (CNS) tumours. The hypothesis was investigated in the Epidemiological Study on childhood Cancer and Leukemia ESCALE ...
Lederman Sally Ann - - 2008
This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at term in lower Manhattan after 11 September 2001, ...
Tamaki Tetsuo - - 2008
OBJECTIVE: This study was conducted to clarify the prevalence of alcohol consumption among pregnant women in Japan and its associated factors. METHOD: 344 institutions participated in the survey which was conducted in February 2006. Each subject was requested to fill out a self-administered anonymous questionnaire. Factors associated with alcohol consumption ...
Alati Rosa - - 2008
BACKGROUND: It is unclear whether fetal alcohol exposure contributes to alcohol use in adolescence. In this study, we examine the association between maternal alcohol use in pregnancy and adolescents' drinking patterns at age 14. METHODS: The association of maternal alcohol exposure with early drinking was examined in 4363 adolescents taking ...
Dovydaitis Tiffany - - 2008
Evidence supports the benefits of fish consumption during pregnancy, primarily because of the effects of n-3 polyunsaturated fatty acids on the neurodevelopment of the fetus. Many fish may also be potent sources of methylmercury and polychlorinated biphenol exposure, which have been shown to have severe negative impacts on both the ...
Taylor William J - - 2008
Methotrexate (MTX) toxicity in psoriatic disease was the focus of discussion at the 2007 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). Plenary presentations and results of a Web-based opinion survey of rheumatologists and dermatologists from GRAPPA, and others from New Zealand, Australia, ...
Alvarez Martha Lucio - - 2008
This qualitative descriptive research aimed to analyze pregnancy dynamics, experienced by a group of women who, at the time, were at most 19 years old, and identify the role attributed to the consumption of alcohol in such dynamics. The research was developed with a group of 20 students from the ...
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