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Fernandez Michael - - 2013
The mechanical integrity of the uterine cervix is critical for a pregnancy to successfully reach full term. It must be strong to retain the fetus throughout gestation and then undergo a remodeling and softening process before labor for delivery of the fetus. It is believed that cervical insufficiency (CI), a ...
Matlow J N - - 2013
INTRODUCTION: Alcohol consumption during pregnancy can lead to Fetal Alcohol Spectrum Disorder (FASD), and because maternal self-reports are often unreliable, biomarkers of alcohol use are sometimes necessary to accurately determine fetal risk. Ethyl glucuronide (EtG), a direct metabolite of ethanol, has been detected in the meconium of infants born to ...
Rosefort Audrey - - 2013
Abstract Chorioangioma is the most common benign vascular placental tumor. It is often small and has no clinical significance. Large chorioangiomata are rarer and can lead to fetal or maternal complications. Chorangiomatosis or chorioangomatosis is even rarer and is defined as a focal or multifocal proliferation of placental capillaries permeating ...
van Poppel Mireille Nm - - 2013
OBJECTIVE: Chemerin is a novel adipokine implicated in inflammation and obesity. We hypothesized that fetal chemerin would be elevated in gestational diabetes mellitus (GDM) and correlate with fetal and maternal adiposity. DESIGN: Observational, longitudinal study SUBJECTS AND MEASUREMENTS: Fetal chemerin was measured separately in arterial and venous cord blood of ...
Bebbere Daniela - - 2013
The insulin-like growth factor 2 receptor (IGF2R) is essential for prenatal growth regulation and shows gene dosage effects on fetal weight that can be affected by in-vitro embryo culture. Imprinted maternal expression of murine Igf2r is well documented for all fetal tissues excluding brain, but polymorphic imprinting and biallelic expression ...
Justice Tiffany - - 2013
There are multiple clinical situations where cryopreservation of sperm is required including sperm banking prior to chemotherapy or radiation treatment for cancer, donor sperm for couples without a male partner, and various etiologies of male factor infertility. Bunge and Sherman presented the first pregnancy resulting from the thawing of cryopreserved ...
Critchell Karon - - 2013
This chapter describes the method used for serial sectioning and soft tissue examination of the Bouin's fixed fetus (mainly whole rat and or mouse fetuses or rabbit fetal heads) for the assessment of developmental and structural abnormalities. Fetuses are examined externally, together with the internal structures of the head as ...
Huang Xiao - - 2013
Physiological pregnancy is associated with an increase in lipids from the first to the third trimester. This is a highly regulated response to satisfy energy and membrane demands of the developing fetus. Pregnancy disorders, such as pre-eclampsia, are associated with a dysregulation of lipid metabolism manifesting in increased maternal plasma ...
Friis Camilla M - - 2013
In the nonpregnant population, there is extensive evidence of a systemic low-grade inflammatory status in relation to excess adipose tissue. Less is known about the relation during pregnancy. Our main objective was therefore to explore the effect of pregnancy on adiposity-related systemic inflammation. This study is a longitudinal cohort study ...
Hori Hiroko - - 2013
When cerebral infarction develops during pregnancy, treatment without adverse effects must be considered not only for the mother but also for the fetus. Because pregnant women were excluded from many clinical trials, clear treatment guidance for them is not shown in the package inserts or guidelines of many drugs. We ...
Uzair Sheikh - - 2013
A 28-year-old woman who was 6 months postpartum following her second pregnancy presented with a history of painful protrusion and weakness of her abdominal wall musculature. Despite having had physiotherapy there was no improvement in muscle strength. MRI scan of her abdominal wall was performed which showed significant diastasis of ...
Fanos Vassilios - - 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, cord blood, placenta, urine, and vaginal secretions. All ...
Straughen J K - - 2013
Differences in body fat distribution contribute to the metabolic abnormalities associated with overweight and obesity; however, such differences have not been adequately explored during pregnancy. Our aim was to compare longitudinal trends in maternal abdominal adipose tissue deposition during pregnancy in overweight/obese compared with normal weight women. Pregnant women, classified ...
Wang Z Z Department of Gynecology, Nanshan Affiliated Hospital of Guangdong Medical College, Shenzhen, China. - - 2013
This work aimed to introduce a new surgical operation for cesarean scar pregnancy (CSP). Transvaginal removal of ectopic pregnancy tissue and repair of a uterine defect were performed in 17 CSP patients. The new surgical operation was performed successfully in all cases. The new surgery operation is safe, effective, and ...
Kemfang Jean Dupont Ngowa JD Obstetrics and Gynecology Unit, Yaounde General Hospital, P.O. Box 5408, Yaounde, Cameroon ; Department of Obstetrics and Gynecology, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, P.O. Box 1364, Yaounde, - - 2013
Klippel Trenaunay syndrome (KTS) is a rare congenital disease characterized by a triad of cutaneous hemangioma, varicose veins and bone or soft tissue hypertrophy. Cases of pregnancy complicated by KTS are rare. There is an increased risk of thrombo-embolic disease and hemorrhage during pregnancy. Both obstetric and anesthetic management of ...
Fouelifack Florent Ymele FY Obstetrics and Gynecology Unit of the Yaounde Central Hospital, - - 2013
Ovarian pregnancy is very rare and to our knowledge, no case has been reported in Cameroon. We herein report a case at the Yaounde Central Hospital. It is the case of a 29 years old woman who consulted in emergency for left pelvic pain at 9 weeks of pregnancy. The ...
Muminhodzic Lejla L Department of Gynaecology and Obstetrics, University Clinical Centre Tuzla, Bosnia and - - 2013
This study aimed at investigating ultrasonographic features of partial hydatidiform mole to establish a proper diagnosis. This was a retrospective study of 70 pregnancies which were divided into two groups: group I--35 pregnant women with a molar pregnancy diagnosed in the first trimester; group II--35 pregnant women with physiological pregnancy ...
Zhang Z - - 2012
Construction of tissue microarray (TMA) to validate the very large number of molecular targets of gene microarray data may provide a high throughput approach in preeclampsia study. However, the intricate structure of the placenta has limited this technique's application. In this study, 80 preeclampsia and 58 normal placental specimens were ...
Badir Sabrina - - 2012
An in-vivo measurement procedure is presented to characterize the mechanical behavior of human uterine cervix during pregnancy. Based on the aspiration method, a new instrument was developed to provide an inherently safe and easy-to-use mechanical testing technique. Initial measurements were performed on non-pregnant women to develop an appropriate measurement protocol. ...
Eborn D R - - 2012
Two experiments were conducted over 3 yr to determine pregnancy rates in beef heifers after a timed artificial insemination (AI) in response to the 7-11 Synch protocol. In Exp. 1, 179 heifers were either fed melengestrol acetate (MGA; 7-11 Synch) or given an intravaginal progesterone (P4)-releasing insert (CIDR; 7-11 CIDR) ...
Sun Mary Y - - 2013
Fetal growth restriction is reported to be associated with impaired placental iron transport. Transferrin receptor (TfR) is a major placental iron transporter in humans but has not been studied in sheep. TfR is regulated by both iron and nitric oxide (NO), the molecule produced by endothelial nitric oxide synthase (eNOS). ...
Rajabi Babak - - 2012
ABSTRACT:: Urothelial carcinoma of the bladder with choriocarcinomatous features is a rare presentation among genitourinary cancers. In this study, the case of a 42-year-old woman who presented with menstrual irregularity and positive urine and serum beta-human chorionic gonadotropin tests is presented. Pelvic ultrasound showed no intrauterine pregnancy. Laparoscopy and hysteroscopy ...
Palacios-Jaraquemada José M - - 2012
In the past decade, the incidence of placenta praevia and placenta accreta has increased and seems to be associated with induced labour, termination of pregnancy, caesarean section and pregnancy at older age. These factors imply some degree of tissue damage, which can modify the decidualisation process, and produce excessive vascular ...
Argañaraz Martin Eduardo - - 2012
Members of TGF-β superfamily play a major role in the endometrial changes involved in the establishment and maintenance of pregnancy. Their deregulated expression and action could lead to absolute or partial failure of embryo implantation. Nonetheless, the precise function and mechanism of many of these cytokines remain unclear. Nodal, a ...
Sheng Guojun - - 2012
The transfer of nutrients from the mother through the chorioallantoic placenta meets the nutritional needs of the embryo during human prenatal development. Although all amniotes start with a similar "tool kit" of extraembryonic tissues, an enormous diversity of extraembryonic tissue formation has evolved to accommodate embryological and physiological constraints unique ...
Parker Rex A RA - - 2012
Because of its lack of ionizing radiation and excellent soft-tissue contrast, magnetic resonance (MR) imaging is being increasingly used in the evaluation of acute abdominal pain in the pregnant patient. Roughly 2% of all pregnancies are ectopic. Although ectopic pregnancy is usually diagnosed on the basis of a combination of ...
Hall Natalie H - - 2012
A rescued female manatee was observed expelling a fetal bone from the vulva. The manatee was anesthetized and diagnosed with uterine retention of a fetal skeleton by ultrasound and hysteroscopy. Episiotomy was performed to gain manual access to the vagina and uterus for removal of the skeleton. Second intention healing ...
Heidar Zahra - - 2012
Tubal ectopic hydatidiform mole is an uncommon but very important complication of pregnancy. The clinical manifestation is the same as ectopic pregnancy and in all of the cases management was the same as tubal ectopic pregnancy. We present a case of tubal ectopic pregnancy that after laparotomy and salpingectomy, pathologic ...
Zhang Peng - - 2012
We present an unusual case of an unstable pelvic fracture during pregnancy period, who suffered fetal death and splenic rupture simultaneously which developed massive delayed hemorrhage in abdomen. When considering potential causes of fetal death, direct trauma to the uterus, placenta, or fetus was not associated with a higher fetal ...
Hunt Beverley J - - 2012
In order to identify the cause of maternal deaths due to thrombotic thrombocytopenic purpura (TTP) and identify future preventative measures we retrospectively reviewed all maternal deaths due to TTP in London from 2003 to 2008 that were confirmed on post-mortem examination. There were three maternal deaths due to sudden cardiac ...
Derrick Matthew - - 2012
Background:Fetal hypoxia-ischemia results in significant morbidity and mortality. Little is known about the timing of death in human stillbirths. The vulnerability of the fetus varies with age at the time of insult but it is unknown what happens to the timing of fetal death in relation to a fetal insult. ...
Deveer Rüya - - 2012
The objective of this study is to evaluate fetal and maternal outcomes of twin pregnancies with intrauterine single fetal death. In 13 cases, intrauterine death of one fetus was found during the first trimester; in 25 cases, it was found after the first trimester. Obstetric complications and fibrinogen levels were ...
Findik Rahime Bedir - - 2012
The aim of this study was to determine the relationship between urinary incontinence (UI) and parameters such as pregnancy, mode of delivery and other factors. The study was based on a questionnaire administered to 761 patients. After their age, menopausal status, number of pregnancies, number of deliveries and history of ...
Franchitto Nicolas - - 2012
  Amniotic fluid embolism (AFE) continues to be one of the most feared complications of pregnancy. A healthy 32-year-old woman died during delivery after a normal 39-week third pregnancy. The family filed a complaint with a criminal court as the causes of death appeared unclear. No risk factor associated with ...
Gomes Manuel C - - 2012
Abstract INTRODUCTION: Maternal mortality is a public health issue,internationally considered an indicator of women's status in society, indirectly translating access to health facilities. However, it is difficult to measure and is usually underestimated by official records. METHODS: Maternal deaths missed by the official statistics in Portugal between 2001 and 2006 ...
- - 2012
Ectopic pregnancy occurs when a fertilized ovum implants on any tissue other than the endometrial lining of the uterus. Approximately 1%-2% of pregnancies in the United States are ectopic; however, these pregnancies account for 3%-4% of pregnancy-related deaths. The ectopic pregnancy mortality ratio in the United States decreased from 1.15 ...
Ritchie J - - 2012
Background and objectives: Pregnancies in women with systemic lupus erythematosus (SLE) and lupus nephritis are considered high-risk due to high rates of maternal and fetal complications. However, there has not been a formal analysis addressing the issue of maternal deaths in these women. The aim of this study was to ...
Ganyaglo Gabriel Y K - - 2012
A 6-year (2004-2009) review of maternal deaths is presented to establish particular trends at the eastern regional hospital (1 of 10 regional hospitals in Ghana). There were a total of 191 maternal deaths over the period, with a total of 19,965 live births, giving a maternal mortality ratio of 957 ...
Mehrotra Seema - - 2012
Herein, we present a case of tubal choriocarcinoma which was diagnosed initially as chronic ectopic pregnancy. During laparotomy we noticed a haemorrhagic friable mass in the left flank, adherent to the bowel. Left-sided salpingoopherectomy was performed. Serum β HCG (human chorionic gonadotropin) levels performed in the postoperative period were elevated. ...
Woderska Aleksandra - - 2012
Maternal brain death during pregnancy is an exceptional case when somatic support might be continued despite diagnosed death. There are only a few cases of maternal brain death during pregnancy reported in the literature and detailed data regarding the frequency of such cases are lacking. The case of a 40-year-old ...
Lotufo Fátima Aparecida - - 2012
The World Health Organization has recommended investigating near-misses as a benchmark practice for monitoring maternal healthcare and has standardized the criteria for diagnosis. We aimed to study maternal morbidity and mortality among women admitted to a general intensive care unit during pregnancy or in the postpartum period, using the new ...
Pasternak Björn - - 2012
To investigate whether an adjuvanted pandemic A/H1N1 2009 influenza vaccine in pregnancy was associated with an increased risk of fetal death. Nationwide register based cohort study. Denmark. All clinically recognised singleton pregnancies that ended between November 2009 and September 2010. Individual level data on exposure to an inactivated AS03 pandemic ...
Bouquet de Jolinière Jean J Department of Gynecology, Fribourg Hospital Fribourg, - - 2012
Recent findings strongly promoted the hypothesis that common pelvic gynecological diseases including endometriosis and ovarian neoplasia may develop de novo from ectopic endometrial-like glands and/or embryonic epithelial remnants. To verify the frequency, the anatomical localization and the phenotype of misplaced endometrial tissue along the fetal female reproductive tract, histological and ...
Aliyu Muktar H - - 2011
The purpose of this study was to examine the association between prenatal alcohol consumption and the occurrence of placental abruption and placenta previa in a population-based sample. We used linked birth data files to conduct a retrospective cohort study of singleton deliveries in the state of Missouri during the period ...
Wilson Andrea L - - 2011
To assess the fertility and pregnancy experiences of rural Malawian women living with obstetric fistula and following surgical repair of fistula. Fertility histories were collected via in-depth interviews with women identified in 2007 as having obstetric fistula and with their family members. Of the 32 affected women interviewed, 17 (53.1%) ...
Adén Ulrika - - 2011
World-wide, many fetuses and infants are exposed to methylxanthines via maternal consumption of coffee and other beverages containing these substances. Methylxanthines (caffeine, theophylline and aminophylline) are also commonly used as a medication for apnea of prematurity.The metabolism of methylxanthines is impaired in pregnant women, fetuses and neonates, leading to accumulating ...
Aye Christina Yi Ling CY Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Aylesbury, UK. - - 2011
While infantile myofibromatosis is the most common mesenchymal tumour of infancy, only around 300 cases have been reported. The authors report a 33-year-old para 1 with an uncomplicated, dichorionic diamniotic twin pregnancy who was diagnosed with an intrauterine death of one twin at 36+5 weeks gestation. At caesarean section, a ...
Tanha Fatemeh Davari FD Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, - - 2011
Hydatidiform moles are abnormal gestations characterized by the presence of hydropic changes affecting some or all of the placental villi. Hydatidiform moles arise as a result of the fertilization of an abnormal ovum. In this report, the patient was a 29 year old Asian woman who had induction of ovulation ...
Shaw Palma - - 2011
The effect of radiation on the fetus has been derived primarily from animal studies and human exposures to diagnostic and therapeutic radiation as well as atomic bomb exposure. Given the variety of sources, there is controversy over the dose of radiation in addition to the other environmental conditions that surrounded ...
Bloom Michael S - - 2010
Maternal exposure to high concentrations of inorganic arsenic (iAs) in naturally contaminated drinking groundwater sources has been associated with an increased risk for the spontaneous loss of clinically recognized pregnancies in several epidemiologic studies. Whereas a large worldwide population depends on drinking groundwater sources with high levels of iAs contamination, ...
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