Search Results
Results 501 - 550 of 1331
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Laslo-Baker Dionne - - 2004
BACKGROUND: Many women of reproductive age are employed in industries involving exposure to organic solvents. Animal toxicological studies and human case reports demonstrate that high exposure to solvents causes neurodevelopmental toxicity in exposed offspring. Data from occupationally exposed women and their children are few. OBJECTIVE: To compare the cognitive, language, ...
Saldeen Pia - - 2004
Omega-3 fatty acids (omega-3 FA) are constituents of the membranes of all cells in the body and are precursors of locally produced hormones, eicosanoids, which are important in the prevention and treatment of various diseases, especially in women. Omega-3 FA are of interest in some of the most common conditions ...
Das Utpala G - - 2004
Ethanol intake during pregnancy alters offspring facial morphology. However, significant variation that may be due to genetic diversity in ethanol metabolizing enzymes occurs. The alcohol dehydrogenase 1B*3 (ADH1B*3) allele is protective for offspring developmental outcome after maternal alcohol drinking in pregnancy and may explain the spectrum of facial morphology. Faces ...
Henriksen Tine Brink - - 2004
The authors studied the association between female and male alcohol intakes at the time of conception and the risk of spontaneous abortion, including early pregnancy loss detected by urinary human chorionic gonadotropin. After a nationwide mailing to about 50,000 members of four trade unions in Denmark in 1992-1994, 430 couples ...
Vartazarmian Raphael - - 2005
RATIONALE: Assessment of the benefits versus risks associated with antidepressant use during pregnancy must include an analysis of possible drug effects on fetal development. Human studies indicate that prenatal fluoxetine exposure is associated with adverse neonatal outcomes. Animal modeling may provide useful information concerning possible long-term effects of prenatal fluoxetine ...
Ramskogler Katrin - - 2004
Carbohydrate-deficient transferrin (CDT) has been well established as a marker for high alcohol consumption. As studies concerning the specificity of CDT in patients with liver disease have shown controversial outcomes, efforts to illuminate mechanisms leading to impaired CDT specificity in this patient group cannot yet be considered successful. Evidence of ...
Crow Scott J - - 2004
OBJECTIVE: The current study examined the change in bulimic symptoms as well as alcohol, drug, and tobacco use during pregnancy in subjects with bulimia nervosa. METHOD: A self-report questionnaire was used to collect retrospective data on eating disorder symptoms and substance use during pregnancy from 129 participants in a long-term ...
Berkovitch Matitiahu - - 2004
AIMS: The number of published studies on the use of amoxycillin/clavulanic acid during pregnancy is small and so is the number of pregnancies investigated in those studies. In this study we wished to investigate prospectively the safety of intrauterine exposure to amoxycillin/clavulanic acid in a relatively large cohort of women. ...
Astley Susan J - - 2004
Fetal alcohol syndrome (FAS) is a permanent birth defect syndrome caused by maternal consumption of alcohol during pregnancy. It is characterised by growth deficiency, central nervous system damage/dysfunction, and a unique cluster of minor facial anomalies. To assess the effectiveness of fetal alcohol syndrome prevention efforts, one must be able ...
Hilaire Michelle L - - 2004
OBJECTIVE: To review the literature for treatment of migraine headaches with sumatriptan during pregnancy. DATA SOURCES: Studies and reports were located in International Pharmaceutical Abstracts (1970-September 2003) and MEDLINE (1966-week 3 September 2003). DATA SYNTHESIS: Research has been performed to evaluate the risk of teratogenesis after sumatriptan exposure in pregnant ...
Kuczkowski Krzysztof M - - 2005
Illicit substance use in pregnancy has received significant media attention over the past 25 years. However, far too little attention has been given to the consequences of the use/misuse of social drugs such as tobacco and ethanol, which are by far the most commonly used/misused substances in pregnancy. While the ...
Kahaleh Michel - - 2004
BACKGROUND: Choledocholithiasis during pregnancy increases the risk of morbidity and mortality for both fetus and mother because of cholangitis and pancreatitis. ERCP has been advocated as safe and effective in pregnant women, but fetal radiation exposure is not routinely monitored. The aim of this study was to record fetal exposure ...
Duarte Paulo C - - 2004
OBJECTIVE: To estimate risk of exposure and age at first exposure to Sarcocystis neurona and Neospora hughesi and time to maternal antibody decay in foals. ANIMALS: 484 Thoroughbred and Warmblood foals from 4 farms in California. PROCEDURE: Serum was collected before and after colostrum ingestion and at 3-month intervals thereafter. ...
Snow Diane M - - 2004
Cocaine use during pregnancy is associated with neurobehavioral problems in school-aged children that implicate alterations in attentional processes, potentially due to impairments in the noradrenergic system. We analyzed locus coeruleus (LC) neurite outgrowth characteristics following the administration of a physiologically relevant dose of cocaine (3.0 mg/kg) issued during critical phases ...
Morrissette Joëlle - - 2004
Fish consumption from the Great Lakes and the St. Lawrence River has been decreasing over the last years due to advisories and increased awareness of the presence of several contaminants. Methylmercury (MeHg), a well-established neurotoxicant even at low levels of exposure, bioaccumulates to differing degrees in various fish species and ...
Lawson Christina C - - 2004
OBJECTIVES: The purpose of this prospective study was to examine caffeine consumption and other signals of early pregnancy. STUDY DESIGN: One hundred and five pregnant, nonsmoking, coffee drinkers ages 18-40 were enrolled by the ninth week after their last menstrual period (LMP). Participants kept daily diaries of beverage and caffeine ...
Kok René D - - 2004
In this study the possible adverse effects of in utero exposure to magnetic resonance (MR) conditions at 1.5 Tesla were examined. Thirty-five children between 1 and 3 years of age, and nine children between 8 and 9 years of age, that were exposed to MR during the third trimester of ...
Lowe Sandra A - - 2004
BACKGROUND: The use of X-rays, computed tomography scanning and nuclear medicine imaging in the pregnant woman is a source of great anxiety for the patient, her family and the treating doctor. METHODS: A literature review of appropriate databases, articles and relevant institutional protocols was performed. Data was sought regarding any ...
Barish Robert J - - 2004
During high-altitude flight, the cosmic radiation dose rate in an airliner is greater than it is at ground level. For a casual traveler, the impact on pregnancy from cosmic radiation exposure during flight is trivial. Pregnant frequent flyers, pilots, and flight attendants can, however, receive exposures that exceed current recommended ...
Abel Ernest - - 2004
Maternal alcohol use during pregnancy is associated with a wide range of adverse outcomes for the child. Many women who drink during pregnancy also have male partners who abuse alcohol. Existing data on paternal effects of alcohol abuse during the preconceptual period and at the time of conception are reviewed. ...
Gauthier Theresa W - - 2004
Because chronic alcohol abuse alters immune defenses and increases infection in adults, we tested the hypothesis that maternal alcohol use during pregnancy would increase the risk of sepsis in very low birth weight (VLBW) premature newborns. We performed a case-controlled analysis of VLBW newborns born at Grady Memorial Hospital (Atlanta, ...
Day Nancy L - - 2004
The association between prenatal exposure to alcohol and growth is linear, and effects have been measured at levels of exposure that are considerably below one drink per day. Thus, with respect to growth deficits, there is no safe level of drinking during pregnancy. Alcohol exposure during gestation causes growth deficits ...
Naidoo Sudeshni - - 2004
Foetal Alcohol Syndrome (FAS) consists of multi-system abnormalities and is caused by the excessive intake of alcohol during pregnancy. The teratogenic effect of alcohol on humans has now been established beyond reasonable doubt and FAS is one of the most important human teratogenic conditions known today. Many investigators have catalogued, ...
Kesmodel Ulrik - - 2004
It has been suggested that future research into the adverse effects of binge drinking in pregnancy should take into account the time of binge drinking, and a method has been proposed. In a representative sample of 1,311 pregnant Danish women in 2000, the agreement between two different measures of binge ...
Botha Nicolette - - 2004
Microcystin-LR (MCLR) has been associated with the development of gastrointestinal complaints in people ingesting cyanobacterial bloom contaminated water. The symptoms usually present a day or two after exposure raising questions as to the toxic effects of MCLR on the gastrointestinal tract. This study investigated the apoptotic effect of ip administered ...
Keiver Kathy - - 2004
BACKGROUND: Prenatal ethanol exposure can retard fetal growth and delay skeletal development. Ethanol also impairs maternal calcium (Ca) homeostasis and this impairment could mediate some of ethanol's effects on the fetal skeleton. Our previous studies suggest that the duration of maternal ethanol consumption may be an important factor for determining ...
Behrens Thomas - - 2004
In Europe household appliances are a major source of indoor 50 Hz magnetic field exposure. A number of epidemiological studies have reported associations between leukemia risk and personal use of household appliances. In the "Norddeutsche Leukämie und Lymphomstudie" (NLL), which was conducted in Northern Germany (Schleswig-Holstein and Lower Saxony) between ...
He Na - - 2004
In our previous studies [J. Comp. Neurol. 435 (2001) 263] we demonstrated that rhesus monkeys born to mothers receiving cocaine orally during the period of pregnancy when neurons destined for the cerebral neocortex were generated displayed inappropriate positioning of neocortical neurons, loss of normal neocortical lamination, and reduction in neocortical ...
Burbacher Thomas M - - 2004
Toxicokinetic studies were conducted following daily inhalation exposure to methanol vapor prior to and throughout pregnancy in adult female Macaca fascicularis monkeys. They were part of a larger study to investigate the effects of chronic methanol exposure on maternal reproductive performance and early offspring effects. In a two-cohort study design, ...
Intorre L - - 2004
The safety of azamethiphos (AZA), an organophosphorous insecticide and the active ingredient of Salmosan, was evaluated in the European eel, seabass and rainbow trout. Fish were bathed in 0.1 ppm AZA for a period of 60, 120 or 240 min. After termination of each treatment fish were transferred to clean ...
Gambichler T - - 2004
BACKGROUND: Ultraviolet (UV) lamps used in commercial sunbeds are usually defined as UVA sources. Although it is well accepted that sunbed exposure significantly increases melanin pigmentation, its capacity to induce epidermal thickening is discussed controversially. OBJECTIVES: The aim of this study was to assess non-invasively the effects of repeated sunbed ...
Kuczkowski Krzysztof M - - 2004
PURPOSE: The prevalence of recreational drug abuse among young women, including in pregnancy, has increased markedly over the past two decades. Cocaine remains the drug commonly used for recreational purposes in pregnancy. However, there appears to be an absence of uniform guidelines for obstetric and anesthetic management of pregnant patients ...
Liu Xiu - - 2004
Epidemiological studies have suggested that adverse experiences in utero predispose individuals to neurobehavioral disorders including drug abuse in adulthood. The present study was designed to examine the hypothesis that maternal endotoxin exposure during pregnancy increases ethanol consumption in adult offspring. Pregnant Sprague-Dawley rats were subjected to lippopolysaccharide (LPS, 1.0 mg/kg, ...
Hanke Wojciech - - 2004
The epidemiological studies presented in this paper refer to the association between agricultural occupation of parents and the incidence of infertility, congenital malformations, miscarriage, low birthweight, small-for-gestational-age (SGA) birth, preterm delivery and stillbirth. The results of the analyses showed that employment in agriculture increases the risk of specific morphological abnormalities ...
Freudenmann Roland W - - 2004
This paper reviews the pharmacology and toxicology of 3,4-methylenedioxy-N-ethylamphetamine (MDEA, "eve"). MDEA is a ring-substituted amphetamine (RSA) like MDMA, its well known N-methyl analog. Both have become very popular substances of abuse in the techno- and house-music scene. They can evoke psychomotor stimulation, mild alterations of perception, sensations of closeness ...
Glinianaia Svetlana V - - 2004
BACKGROUND: Research on the potential impact of air pollution on the health of adults and children has grown rapidly over the last decade. Recent studies have suggested that air pollution could also be associated with adverse effects on the developing fetus. This systematic review evaluates the current level of epidemiologic ...
Chang Grace - - 2005
Pregnant women continue to drink despite evidence that prenatal alcohol consumption can negatively affect fetal growth and development. Because no universally safe level of prenatal alcohol use has been established, it is beneficial to identify and modify a woman's prenatal alcohol use early in her pregnancy, particularly as her past ...
Widaman Keith F - - 2003
OBJECTIVE: The primary aims of this study were to model the form of the relation between prenatal exposure to phenylalanine (Phe) and measures of offspring intellectual development and to estimate the developmental relations of maternal demographic, pregnancy-related, and perinatal variables on offspring intelligence during infancy and childhood. METHODS: The participants ...
Anttila Petra - - 2003
BACKGROUND: The detection of excessive alcohol consumption by laboratory methods continues to lack sensitivity and specificity. Recent studies have suggested that diagnostic improvement may be achieved by combining carbohydrate-deficient transferrin (CDT) and gamma-glutamyltransferase (GT) measurements into a marker defined as gamma-CDT. METHODS: We developed a new approach for determining gamma-CDT ...
Tabacova Sonia - - 2003
BACKGROUND: Adverse pregnancy outcomes following the use of angiotensin-converting enzyme (ACE) inhibitors, including enalapril, have been reported in descriptive studies. However, no analytical studies on the relationship between the adverse outcomes and enalapril gestational exposures are available. OBJECTIVES: To explore the association between enalapril exposure and adverse outcomes in pregnancy, ...
Bharti Des - - 2003
Little is known about the effect of inhalation of methanol and other solvents on the pregnancy and the growth of the fetus. We report a preterm male infant who developed cerebral infarcts in utero, leading to large areas of bilateral frontal cortical leukomalacia following chronic maternal inhalation of carburetor-cleaning fluid ...
Tolstrup J S - - 2003
BACKGROUND: Consumption of caffeine and alcohol is suspected to affect pregnancy outcome. Use of both stimulants is widespread and even minor effects on fetal viability are of public health interest. METHODS: We performed a nested case-control study using prospective data from a population-based cohort comprising 11088 women aged 20-29 years. ...
Wurst Friedrich Martin - - 2003
Current biological state markers remain suboptimal with regard to sensitivity and specificity for monitoring recent alcohol consumption in various settings. Furthermore, these biomarkers can be influenced by age, gender and a variety of substances and non-alcohol-associated diseases and do not cover fully the time axis for alcohol intake. Ethyl glucuronide ...
Ken Joyner
this paper, microwave radiation will be regarded as a subset of the radiofrequency (RF) band.) Claims of adverse health effects due to EMR exposure include increased cancer rates, adverse pregnancy outcomes and cataract induction
Kashiwagi Maki - - 2003
BACKGROUND: Maternal cocaine abuse in pregnancy is associated with complications such as intrauterine growth retardation, abruptio placentae, and preterm delivery. CASE: We report what is, to our knowledge, the first published observation of fetal bilateral renal agenesis associated with a vascular disruption syndrome comprising upper limb reduction defect and a ...
Meschke Laurie L - - 2003
Fetal alcohol exposure is a common cause of birth defects and developmental disorders. As many as 1 in 100 children in the United States are believed to be affected by fetal alcohol exposure. Characteristics of fetal alcohol syndrome (FAS) include abnormal facial features, growth impairment, problems with learning, memory, attention ...
Göransson Mona - - 2003
Maternal alcohol consumption is a major health hazard for the fetus. Sweden has an extensive system of public antenatal care clinics, whose mission is to detect and prevent this type of health hazards. However, very few cases of alcohol consumption during pregnancy are detected. The aim of this study was ...
Anton Dan - - 2003
OBJECTIVES: Assessing exposure to physical risk factors during variable noncyclic work can be problematic. The purpose of this study was to modify an existing data reduction method for directly quantifying physical exposures during variable noncyclic work. METHODS: Myoelectric activity of the finger flexors of two groups of workers, heavy equipment ...
Whitehead Nedra - - 2003
Few studies have examined the effect of binge drinking on human fetal growth. The authors studied the effect of binge drinking 3 months before pregnancy and during the last 3 months of pregnancy on small-for-gestational-age (SGA) birth, using data from the Pregnancy Risk Assessment Monitoring System (PRAMS). PRAMS is an ...
Poggi Sarah H - - 2003
OBJECTIVE: Fetal alcohol syndrome (FAS) is the most common nongenetic cause of mental retardation. Peptides NAPVSIPQ (NAP) and SALLRSIPA (SAL), related to activity-dependent neuroprotective protein (ADNP), prevent alcohol-induced damage in a mouse model of FAS. Our objective was to characterize ADNP in this model to relate this protein to the ...
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