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Rassouli M M Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, - - 2011
SUMMARYToxoplasma gondii, an obligatory intracellular protozoan parasite, is one of the causative agents of ovine abortion, as reported in many countries. Different techniques are being used to detect this pathogen in infected ovine fetuses. One of the most sensitive and specific diagnostic techniques is Nested-PCR amplification of the B1 target ...
Akhtar Mohammad Irfan - - 2011
Acute aortic dissection in pregnancy is a serious situation, because rapid and appropriate surgical decision making is required to save the life of both mother and baby. Aortic dissection is rare in young women but is likely during pregnancy (third trimester) secondary to the hyperdynamic and hypervolaemic circulatory state associated ...
Stubbs Benjamin Michael - - 2011
Gastrointestinal stromal tumour (GIST) in pregnancy is rare. There have been only three previously reported cases, all of which have been diagnosed on postoperative histology. The authors present the first case of a preoperatively diagnosed GIST arising in a 31-year-old pregnant woman. With a suspected diagnosis, the patient was managed ...
Vranes Mile - - 2011
In the current article, 3 cases of aortic aneurysm and dissection in pregnant patients with Marfan's syndrome are reported. It is well known that pregnancy is a risk factor for the development of aortic aneurysm and dissection in women with Marfan's syndrome since it is shown that dissection can develop ...
Navada H Mahesha HM Department of Obstetrics and Gynaecology, Father Muller Medical College, Mangalore, Karnataka 565002, - - 2011
Chronic pelvic inflammatory disease (PID) in the form of peritoneal abscess during pregnancy is almost unheard entity. Early and antenatal diagnosis may be difficult or may be revealed only during caesarean section. We report a case of peritoneal abscess secondary to pelvic inflammatory disease incidentally found at repeat caesarean section. ...
Bansal Jyoti J College of Dental Sciences and Research, Maharishi Markandeshwar University, Mullana, - - 2011
Preterm birth is the leading perinatal problem with subsequent morbidity and mortality in developed as well as developing nations. Among the various possible environmental, genetic, demographic, psychosocial and obstetric risk factors responsible for premature labor, poor oral health with periodontal infection has also emerged as a potential and modifiable risk ...
Coyral-Castel S - - 2010
Recently, one Quantitative Trait Locus (QTL) of female fertility located on Bos Taurus chromosome 3 (BTA3), QTL-F-Fert-BTA3, has been identified in Holstein breed. It is implied in the success rate after the first AI (AI1) in cow. The failure of pregnancy can be due to several factors involved in the ...
Boldorini Renzo - - 2010
Given the conflicting results of the few published studies, the aim of this retrospective molecular-based study of 10 aborted fetuses that underwent complete autopsy and 10 placentas was carried out to determine whether BK polyomavirus (BKV) can be transmitted transplacentally. The interruption of pregnancy was due to a miscarriage (five ...
Boldorini Renzo - - 2010
Given the conflicting results of the few published studies, the aim of this retrospective molecular-based study of 10 aborted fetuses that underwent complete autopsy and 10 placentas was carried out to determine whether BK polyomavirus (BKV) can be transmitted transplacentally. The interruption of pregnancy was due to a miscarriage (five ...
Toti Paolo - - 2011
 Histopathological chorioamnionitis (HCA) is caused by microbial-driven infiltration of leukocytes to the maternal-fetal interface resulting in adverse neonatal outcomes in a subset of pregnancies. The role of placental villus macrophages (i.e. Hofbauer cells, HBCs) in the pathophysiology of HCA is unelucidated.  The number of HBCs in human term placental villi ...
Henrich W - - 2011
Placenta increta is a rare event in pregnancy, but is associated with serious maternal morbidity and mortality due to life threatening hemorrhage. The incidence has increased due to high Cesarean rates. We describe a case of placenta previa increta in a dichorionic twin pregnancy, which was successfully treated conservatively, to ...
Sroczynski Tomasz - - 2010
During pregnancy, especially during its third trimester, most pregnant women reported respiratory discomfort (dyspnea), despite the absence of previously coexisting respiratory illnesses. The aim of this study was to determine the reason for this discomfort. The study included 24 women examined before and after childbirth. Evaluation of respiratory complains was ...
Jacques Suzanne M - - 2011
ABSTRACT We report 51 placentas diagnosed with eosinophilic/T-cell chorionic vasculitis (E/TCV), an unusual form of chorionic vasculitis characterized by an infiltrate composed predominantly of CD3+ T cells and eosinophils. The placentas were all 3rd trimester, with 48 (94.1%) being term. Forty-seven (92.2%) were singleton placentas, and the remaining 4 were ...
Carter Anthony M - - 2011
It is now possible to view human placentation in an evolutionary context because advances in molecular phylogenetics provide a reliable scenario for the evolution of mammals. Perhaps the most striking finding is the uniqueness of human placenta. The lower primates have non-invasive placentae and even tarsiers and New World monkeys ...
- - 2010
We sought to review the risks of placenta accreta, increta, and percreta, and provide guidance regarding interventions to improve maternal outcomes when abnormal placental implantation occurs. Relevant documents were identified through a search of the English-language literature for publications including ≥1 of the key words "accreta" or "increta" or "percreta" ...
Uusküla Liis - - 2011
Increased epigenetic variability in the placenta may have evolved in response to its role in mediating the conflicting demands of the mother and fetus. One essential guardian of early pregnancy maintenance is the placental hormone human chorionic gonadotropin (HCG). Among the four primate-specific duplicate HCGβ-coding genes, chorionic gonadotropin-β8 (CGB8) and ...
Burton G J - - 2011
Deportation of syncytial sprouts into the maternal circulation during early pregnancy is a well-accepted phenomenon. Whether the process continues throughout pregnancy has been more contentious. This study aimed to resolve the question through the study of serial sections derived from 5 normal term placentas. In each case, sprouts containing euchromatic ...
Traeder J - - 2010
Chronic histiocytic intervillositis of the placenta (CHI) is a rare and poorly understood pathology which may occur in all trimesters. The most conspicuous feature is a histiocytic infiltration of the intervillous space without involvement of the villous parenchyma. In this report on CHI, we re-evaluate a series of four cases ...
Nadir Yona - - 2010
Heparanase is an endo-β-D-glucuronidase dominantly involved in cell invasion, tumor angiogenesis and metastasis. Recently, we demonstrated increased levels of heparanase, tissue factor pathway inhibitor (TFPI)-2 and vascular endothelial growth factor (VEGF)-A in early miscarriages (Nadir et al., Thromb Res, 2010). Herein, we investigated the role of heparanase in third trimester ...
Yu Mei - - 2010
To summarize our experiences in the diagnosis and treatment of placenta accreta in the second trimester of pregnancy. We retrospectively analyzed the clinical data of 31 patients were admitted to Peking Union Medical College Hospital with placenta accreta in the second trimester of pregnancy from January 2002 to January 2010. ...
Robinson Barrett K - - 2010
OBJECTIVE: To compare strategies for the timing of delivery in individuals with placenta previa and ultrasonographic evidence of placenta accreta, and to determine the optimal gestational age at which to deliver individuals. METHODS: A decision tree was designed comparing nine strategies for delivery timing in an individual with placenta previa ...
Soni S - - 2010
With 2 figures and 2 tables SUMMARY: Apoptosis plays a central role in organ development, homeostasis and immune defence in multicellular organisms and is strictly controlled in part by members of Bcl-2 family. The Bcl-2 is a pro-survival molecule identified through its involvement in B-cell lymphomas. The aim of the ...
Sentilhes Loïc - - 2010
The aim of this study was to estimate the fertility and pregnancy outcomes after successful conservative treatment for placenta accreta. This retrospective national multicenter study included women with a history of conservative management for placenta accreta in French university hospitals from 1993 through 2007. Success of conservative treatment was defined ...
Amash Alaa - - 2010
Interleukin-6 (IL-6) is one of the main proinflammatory mediators of hypertension and endothelial dysfunction in preeclampsia. In this study, we investigated the capacity of the preeclamptic placenta to secrete IL-6 and the effect of magnesium sulfate (MgSO(4)) on it. Placentas from normotensive (37-40 weeks) and preeclamptic (36-40 weeks) pregnancies were ...
Tomas Sandra Zekic - - 2010
To investigate histopathologic findings, placental diameters and characteristics of syncytial knots in the placentas from idiopathic intrauterine growth retardation (IUGR) pregnancies, and to compare them with a normal birth weight group. Based on strict eligibility criteria, this prospective case-control study included 52 term placentas from idiopathic IUGR pregnancies and 69 ...
Zhu Xueqiong - - 2010
Aquaporins are a family of membrane-bound water channel proteins that regulate the flow of water across a variety of biological membranes. The expression of aquaporin 8 and aquaporin 9 has been demonstrated in human chorioamniotic membrane and placenta. But their roles in the pathophysiology of polyhydramnios are unclear. To study ...
Masumoto Akio - - 2010
It has been reported that prolactin (PRL) is cleaved to 14 or 16 kDa fragments by cathepsin D in vitro and in vivo, and that such fragments exhibit antiangiogenic and proapoptotic properties. The aim of this study was to investigate the relationship between pregnancy induced hypertension (PIH) and the placental ...
Akiyama Shizuko - - 2010
Maternal circadian information has been reported to play an important role in fetal physiology and development. Hormones and nutrition have been mainly investigated as circadian cues from mother to fetus. However, the influences of circadian properties of the pregnant reproductive organs on fetuses have not been fully investigated. To gain ...
Rosenberg Tom - - 2011
To investigate risk factors and pregnancy outcome of patients with placenta previa. A population-based study comparing all singleton pregnancies of women with and without placenta previa was conducted. Stratified analysis using multiple logistic regression models was performed to control for confounders. During the study period, there were 185,476 deliveries, of ...
Fokina Valentina M VM Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555-0587, - - 2011
We sought to determine whether gestational age affects the transplacental transfer and metabolism of buprenorphine (BUP). Transfer of BUP (10 ng/mL) and its [ (3)H]-isotope was determined across placentas of 30 to 34 weeks of gestation utilizing the technique of dual perfusion of placental lobule. Concentration of the drug in ...
TAKESHITA Ai - - 2010
The complement system is thought to be precisely regulated during pregnancy. We have examined specific gene profiles in mouse placentas causing spontaneous abortion and found notable up-regulation of adipsin, a complement activating factor. The aim of the present study was to determine the basic kinetics and localization of adipsin in ...
Takahashi Hironori - - 2010
Uterine artery embolization (UAE) is becoming a common treatment for symptomatic leiomyoma. Several pregnancies following UAE have been reported. However, reports are still limited and the risk of complications remains unknown. A primigravida conceived after UAE for leiomyoma. She delivered spontaneously at 34 weeks plus 2 days after premature rupture ...
Hossain Nazli - - 2010
OBJECTIVE: To determine the risk factors in pregnancies complicated with abruptio placenta METHODS: Case-control study. The study was conducted at department of Obstetrics and Gynecology Unit 3, Civil Hospital, Dow University of Health Sciences Karachi. The study period was from January to December 2008. All pregnant women who were diagnosed ...
Takeshita Ai - - 2010
Placental complement has the potential to induce autologous embryo injury. We have previously found a significant elevation of adipsin, an activating factor of the alternative complement pathway, in mouse placentas from spontaneous abortions. The present study was aimed to evaluate regulation of the alternative complement pathway in placentas of mouse ...
Brubel R - - 2010
Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuropeptide with survival-promoting actions, has been observed in endocrine organs and is thought to play a role in reproductive functions, including pregnancy. PACAP occurs in two forms, 27 and 38 amino acid residues, with PACAP38 being the predominant form in human tissues. In the ...
Saleemuddin Aasia - - 2010
Abstract Fetal thrombotic vasculopathy (FTV) is a placental lesion characterized by regionally distributed avascular villi and is often accompanied by upstream thrombosis in placental fetal vessels. Previous studies, using preselected populations, have shown associations of this lesion with adverse neurodevelopmental outcomes and potentially obstructive lesions of the umbilical cord. We ...
Madan Ichchha - - 2010
Idiopathic vaginal bleeding, a common complication of pregnancy, increases the risk of small-for-gestational age (SGA) neonate, preeclampsia and preterm delivery and can be the only clinical manifestation of intra-amniotic infection and/or inflammation (IAI). Placenta previa is thought to be protective against ascending intrauterine infection, yet an excess of histologic chorioamnionitis ...
Uzelac P S - - 2010
Whether the placenta contributes to some of the abnormal hormonal profiles in gestational diabetes mellitus (GDM) pregnancies and whether GDM affects placental endocrine signaling pathways are yet to be established. The objective of this study was to investigate differences in the expression of the placental steroid and peptide hormone synthesis-related ...
Balakrishnan B - - 2010
OBJECTIVE: To study transplacental transfer and biotransformation of genistein in the human placenta. STUDY DESIGN AND OUTCOMES: Human placentae obtained from healthy term singleton pregnancies were utilised in a dual re-circulating model of ex-vivo placental perfusion. Four placentae were perfused for 180min following addition of genistein (10ng/mL) to the maternal ...
Balakrishnan Biju - - 2010
OBJECTIVE: The objective of the investigation was to study placental transfer and conjugation of bisphenol A (BPA) across the human placenta. STUDY DESIGN: Human placentae obtained from healthy term singleton pregnancies were utilized in a dual recirculating model of ex vivo placental perfusion. Seven placentae were perfused with BPA (10 ...
Maltepe Emin E Department of Pediatrics, Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, 513 Parnassus Ave. HSE-1401, Box 1346, San Francisco, CA 94143-1346, USA. - - 2010
The placenta provides critical transport functions between the maternal and fetal circulations during intrauterine development. Formation of this interface relies on coordinated interactions among transcriptional, epigenetic, and environmental factors. Here we describe these mechanisms in the context of the differentiation of placental cells (trophoblasts) and synthesize current knowledge about how ...
Jiang Yi-zhou - - 2010
The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, mediates many biological processes, including fetal development. In this study, we examined AhR protein expression in human placentas from normal (N) and severe preeclamptic (sPE) pregnancies, as well as human fetal tissues from the second trimester of pregnancy, using immunohistochemistry and/or ...
Swieca A - - 2010
During pregnancy the activity of AMP-deaminase in developing human placenta gradually decreases, being in homogenates of mature, term placenta (approximately 40 week of gestation) one fourth to one third of that in homogenates of immature (approximately 25 week of gestation) organ. The gradual decrease of activity correlates inversely with the ...
Beagley J C - - 2010
Retained fetal membranes (RFM) in cattle have adverse effects on fertility and production. Understanding the pathophysiology and causes of RFM is important for managing this disease. The hormonal processes that lead to normal placental separation are multifactorial and begin before parturition. A variety of risk factors, including early or induced ...
Oyinloye Olalekan I - - 2010
The purpose of this study was to assess the risk of persistence of transverse lie detected earlier in pregnancy and associated predisposing factors using follow-up ultrasound (US). A longitudinal study was carried out from January 2004 to august 2004 at Federal Medical centre, Lokoja, Nigeria. All singleton pregnancies, with ultrasound ...
Bouwman M G - - 2010
There are only a few reports on the histology of placental tissue of pregnancies from mothers with Fabry disease. Fabry disease is a lysosomal disorder caused by alpha-galactosidase A deficiency. Extensive glycosphingolipid (GSL) accumulation in fetal and maternal placenta tissue obtained from a Fabry mother and her affected male newborn ...
Dembinski Jörg - - 2010
Importance of the field: Parvovirus B19 (B19V) infection in utero causing fetal anemia and non-immune hydrops fetalis (NIHF) is a potentially life-threatening event for the fetus. Postexpositional non-invasive diagnosis is based on maternal IgG/IgM response and detection of viral genome in maternal blood. Serologic testing directs prenatal follow-up. Fetal infection ...
Hull Andrew D - - 2010
Placenta accreta is the abnormal adherence of the placenta to the uterine wall. Where placenta accreta is present, the failure of the placenta to separate normally from the uterus after delivery is accompanied by severe postpartum hemorrhage. The best outcomes in placenta accreta are in prenatally diagnosed electively delivered cases. ...
Haas Dorothea - - 2010
Holoprosencephaly (HPE) is the most common structural malformation of the developing forebrain in humans. The HPE phenotype is extremely variable and the etiology is heterogeneous. Among a variety of embryological toxins that can induce HPE, inhibitors, and other pertubations of cholesterol biosynthesis have been shown to be important factors, most ...
Provansal Magali - - 2010
OBJECTIVE: To determine the fertility and obstetric outcomes after conservative management of placenta accreta. METHODS: A retrospective observational cohort study of all identified cases of placenta accreta from 1993 to 2007 in 2 tertiary university hospitals in France. For patients treated conservatively, maternal and fetal morbidity, reproductive function, fertility, and ...
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