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Floreani Annarosa - - 2013
Acute hepatitis C is a rare event in pregnancy. The most common scenario is chronic hepatitis C virus (HCV) infection in pregnancy. During pregnancy in women with chronic HCV infection a significant reduction in mean alanine aminotransferase levels has been reported, with a rebound during the postpartum period. In few ...
Honegger Jonathan R JR 1] The Center for Vaccines and Immunity, Nationwide Children's Hospital, Columbus, Ohio, USA. [2] Department of Pediatrics, The Ohio State University School of Medicine, Columbus, Ohio, - - 2013
Globally, about 1% of pregnant women are persistently infected with the hepatitis C virus (HCV). Mother-to-child transmission of HCV occurs in 3-5% of pregnancies and accounts for most new childhood infections. HCV-specific CD8(+) cytotoxic T lymphocytes (CTLs) are vital in the clearance of acute HCV infections, but in the 60-80% ...
Howland Robert H - - 2013
The newly approved drug Diclegis(®), indicated for the treatment of nausea and vomiting associated with pregnancy, has a very interesting background story going back more than 50 years, in which science, celebrity individuals, the media, and the courts crossed paths. The story illustrates how concepts of truth, evidence, objectivity, and ...
Nzila Alexis - - 2013
Malaria remains the leading cause of mortality and morbidity in children under the age of 5 years and pregnant women. To counterbalance the malaria burden in pregnancy, an intermittent preventive treatment strategy has been developed. This is based on the use of the antifolate sulfadoxine/pyrimethamine, taken at specified intervals during ...
Bring Hanna Stormdal - - 2013
To compare causes of stillbirth in preterm and term pregnancies. Cohort study. All delivery wards in Stockholm, 1998-2009. Stillbirths from singleton pregnancies of gestational age ≥ 22(+0) (n=1089) extracted from a web-based database including all stillbirths in the major Stockholm area since 1998. The parents of the stillborns were all ...
Ransy Doris Gladys - - 2013
Coreceptor switch from CCR5 to CXCR4 is associated with HIV disease progression. To document the evolution of coreceptor tropism during pregnancy, a longitudinal study of envelope gene sequences was performed in a group of pregnant women infected with HIV-1 of clade B (n=10) or non-B (n=9). PCR amplification of the ...
Siega-Riz Anna Maria - - 2013
The impact of the obesity epidemic on women of childbearing age has been of particular concern in recent years as a result of studies linking maternal weight status to long-term adverse outcomes for obese mothers and their offspring. The US Institute of Medicine developed new gestational weight gain guidelines based ...
Brutus Laurent - - 2013
Plasmodium vivax is a major cause of illness in areas with low transmission of malaria in Latin America, Asia, and the Horn of Africa. However, pregnancy-associated malaria remains poorly characterized in such areas. Using a hospital-based survey of women giving birth and an antenatal survey, we assessed the prevalence rates ...
Sahu L L Department of Obstetrics and Gynecology, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, - - 2013
Endemic in major parts of Africa and Middle East, Schistosoma haematobium is a common cause of recurrent urogenital infections and obstetric complications such as spontaneous abortions, ectopic pregnancies, and low birth weight babies. The involvement of fallopian tubes is not rare in endemic areas and may predispose to ectopic pregnancy ...
Bielanski A - - 2013
This study deals with the potential for the introduction of infectious agents through the use of animal-derived products. The efficacy of a recombinant bovine trypsin (RBTr) as a replacement for porcine pancreatic trypsin and a disinfectant for bovine herpesvirus-1 (BHV-1)-infected embryos was investigated according to the sanitary guidelines of the ...
Chandelia Sudha - - 2013
Congenital malaria is a rare disease both in endemic and non-endemic areas. It is seldom suspected due to its rarity and the fact that its signs and symptoms may be similar to those with neonatal sepsis. Furthermore, clues such as a history of maternal travel to an endemic area during ...
Capretti Maria Grazia - - 2013
The effectiveness of Toxoplasma gondii (Tg) screening during pregnancy in areas with a low prevalence of the infection is debated.We investigate the Tg-serological status and the rate of primary infection in a cohort of pregnant women and the rate of Congenital Toxoplasmosis among their infants during a three-year period in ...
Agudelo Olga - - 2013
The frequency of pregnancy-associated malaria is increasingly being documented in American countries. In Colombia, with higher frequency of Plasmodium vivax over Plasmodium falciparum infection, recent reports confirmed gestational malaria as a serious public health problem. Thick smear examination is the gold standard to diagnose malaria in endemic settings, but in ...
Bopegamage Shubhada - - 2013
The role of viral infections in preterm prelabor rupture of the membranes (PPROM) is not established. Studies on the presence of viral genomes in the amniotic fluid (AF) collected in pregnancies complicated by PPROM show contradictory outcomes. To investigate AF samples of PPROM pregnancies for the presence of viral genomes. ...
Li Min - - 2013
Abstract Objective To evaluate the association between maternal influenza and congenital heart defects (CHDs), and whether the use of traditional Chinese medicine (TCM) or Western medicine (antibiotics, antipyretic-analgesic drugs) modified this association. Method We analysed 294 fetuses with CHDs and 416 control fetuses without any abnormalities identified from February 2010 ...
Norum Jan - - 2013
It is challenging to obtain high quality obstetric care in a sparsely populated area. In the subarctic region of Norway, significant distances, weather conditions and seasonable darkness have called for a decentralized care model. We aimed to explore the quality of this care. A retrospective study employing data (2009--11) from ...
Bruner David I - - 2013
While complete molar pregnancies are rare, they are wrought with a host of potential complications to include invasive gestational trophoblastic neoplasia. Persistent gestational trophoblastic disease following molar pregnancy is a potentially fatal complication that must be recognized early and treated aggressively for both immediate and long-term recovery. We present the ...
Burke Kerry Anne - - 2013
Malaria is the tropical disease most commonly imported into the United Kingdom (UK) and it can have serious consequences if left untreated in pregnancy (1). Misdiagnosis and treatment delay are the most commonly given reasons for malarial deaths in Europe (2) and there are currently no guidelines addressing the recognition ...
Obieche Anthonia O - - 2013
Background: Prompt and effective case management is one of the control measures for malaria during pregnancy. The objective of the study was to assess treatment patterns of presumed cases of malaria during pregnancy in a Nigerian tertiary health care facility. Methods: A cross-sectional study involving immediate postpartum women admitted to ...
Hoffman Risa M RM *Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA; †Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA; and ‡National Vaccine Program Office/Office of the Assistant Secretary for Health/Office of the Secretary/Department of Health and Human Services, Washington, - - 2013
Women who use antiretroviral therapy (ART) solely for the prevention of mother-to-child transmission of HIV discontinue postpartum. We hypothesized that women discontinuing ART by 6 weeks postpartum ("discontinuers") would have elevated postpartum inflammatory biomarker levels relative to women remaining on ART postpartum ("continuers"). Data from HIV-infected pregnant women enrolled in ...
Rowe Jared H - - 2013
Pregnancy in placental mammals offers exceptional comprehensive benefits of in utero protection, nutrition, and elimination of metabolic waste for the developing fetus. However, these advantages also require durable strategies to mitigate maternal rejection of fetal tissue expressing foreign paternal antigens. Since the initial postulate of expanded maternal immune tolerance by ...
Lassen Jonathan - - 2013
Because parvovirus B19 infection in pregnancy has been associated with infant morbidity and mortality in case reports and after intrauterine transfusion, we tested the population-based association using serum and hospital data of high quality. We established a cohort of 113 228 children born to women tested for parvovirus B19 infection ...
Than Nwe Ni - - 2013
Abnormalities of liver function (notably rise in alkaline phosphatase and fall in serum albumin) are common in normal pregnancy, whereas rise in serum bilirubin and aminotransferase suggest either exacerbation of underlying pre-existing liver disease, liver disease related to pregnancy or liver disease unrelated to pregnancy. Pregnant women appear to have ...
Conde-Ferráez Laura - - 2013
To investigate if HPV cervical infection is associated with spontaneous abortion in a Mexican population. Case control study including 281 women from two Social Security Hospitals in Merida, Mexico. Cases were women with spontaneous abortion attending for curettage, and controls were pregnant women at term who attended for delivery. HPV ...
Piñeros Juan Gabriel - - 2013
In malaria-endemic regions of Latin America, little is known about malaria in pregnancy. To characterize the clinical and laboratory findings of maternal infection, we evaluated 166 cases of pregnant women infected with Plasmodium spp. in a prospective study conducted in northwestern Colombia during 2005-2006. A total of 89.8% (149 of ...
Mineo Shoichiro S Department of Infectious Diseases, Kyorin University School of Medicine, Tokyo, - - 2013
Pregnant women are highly susceptible to malaria infection because of their low immunity and are at increased risk of maternal illness or death, in addition to spontaneous abortion, stillbirth, premature delivery, and low birth weight. However, the detailed pathogenesis of maternal malaria remains unclear. In this study, we evaluated a ...
Konstantinov Sergey R - - 2013
Pregnancy has a beneficial influence on the course of certain autoimmune diseases such as inflammatory bowel disease (IBD). It was recently reported that during pregnancy the microbiome undergoes profound changes that are associated with host physiological and immunological adaptations. Here we propose that microbiome remodeling during pregnancy is an active ...
Belbis G - - 2013
During the incursion of bluetongue virus (BTV) serotype 8 in Europe, an increase in the number of abortions in ruminants was observed. Transplacental transmission of BTV-8 in cattle and sheep, with subsequent foetal infection, is a feature of this specific bluetongue serotype. In this study, BTV-8 ability to cross the ...
Barnea Eytan R - - 2013
Pregnancy and autoimmune disorders (ADs) coexist in a delicate balance. Whereas women are disproportionately affected by ADs - frequently occurring during reproductive years - the disease often improves during pregnancy, unless severe. However, when ADs are at an advanced stage, both mother and fetus can be severely affected. Maternal AD ...
Elston Carly A - - 2013
In the absence of systematic studies in pregnant and lactating women, recommendations for the treatment of infections during pregnancy are based on animal studies, accumulated evidence from clinical use and case reports, as well as published consensus statements and expert opinion. This article examines the evidence basis for the treatment ...
Waight Maria T - - 2013
The aims of the study were to determine the prevalence of sexually transmitted diseases during pregnancy (STDs/P) in Louisiana, the association of maternal characteristics with STDs/P, and the association of STDs/P with low birth weight and preterm birth. STDs surveillance data from 2006-2009 were linked with 2007-2009 birth certificate data. ...
Bajwa Sukhwinder Kaur SK Department of Obstetrics and Gynaecology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab, - - 2013
Pyrexia can be extremely threatening during the normal progression of pregnancy if it occurs during the early phase of gestation as compared to the latter half of pregnancy. The degree of temperature rise, stage of pregnancy, and duration of the underlying illness are the important determinants for the outcome of ...
Moussiliou Azizath - - 2013
BACKGROUND: Despite widespread parasite resistance to sulphadoxine-pyrimethamine (SP) its use for intermittent preventative treatment during pregnancy remains the policy in Benin and throughout most of sub-Saharan Africa. METHODS: In a prospective study, 982 pregnant women were recruited in Benin and followed until delivery. The prevalence of point mutations in the ...
Ahlin Kristina - - 2013
OBJECTIVE:: To investigate the link between infection-related risk factors for cerebral palsy subtypes in children born at term. METHODS:: A case-control study was performed in a population-based series of children with cerebral palsy born at term (n=309) matched with a control group (n=618). The cases were divided into cerebral palsy ...
Leli C - - 2013
Aim: Candida infection is one of the main causes of vulvovaginitis. The experience of symptoms of vulvovaginitis during pregnancy changes in relation to clinical, behavioral, and demographic factors. Candidiasis is associated with an increased risk of delivery complications. In some studies pregnant women are found more symptomatic than non-pregnant women, ...
Parsons Jessica - - 2013
This article exposes the need for support for midwives, to ensure that they are equipped to meet the needs of deaf parents to be. It uncovers research which demonstrates the urgent need for an increase in awareness, education and resources; and the reasons that deaf people have higher rates of ...
Tsikouras Panagiotis - - 2013
Abstract Presentation of uterine prolapse is a rare event in a pregnant woman, which can be pre-existent or else manifest in the course of pregnancy. Complications resulting from prolapse of the uterus in pregnancy vary from minor cervical infection to spontaneous abortion, and include preterm labor and maternal and fetal ...
Cha Agnes - - 2013
The use of raltegravir (RAL) is not preferred to prevent perinatal transmission in pregnancy due to lack of safety and pharmacokinetic data in this population. Data have been limited to few case reports of patients who present for treatment late in pregnancy, have multidrug resistance, or have poor adherence, requiring ...
Wagner N - - 2013
Abstract Introduction Human Cytomegalovirus (CMV) infection during pregnancy is the most frequent viral cause of intrauterine infection and responsible for various cerebral and other ultrasound abnormalities of the fetus. It is the leading infectious cause of mental retardation and sensorineural deafness in affected newborns and infants. We present three cases ...
Pan Calvin Q - - 2013
The management of chronic hepatitis B (CHB) during pregnancy remains a challenge and involves various aspects of maternal-fetal care. Despite the standard immunoprophylaxis, a significant portion of infants born to highly viremic mothers remain infected with hepatitis B virus (HBV). Emerging data suggest that antiviral therapy in the third trimester ...
Thackeray Rosemary - - 2013
Congenital cytomegalovirus (CMV) is the leading cause of birth defects and developmental delays in the United States. However, only 13-22 % of women in the United States have heard of CMV. This research assessed (1) the quantity and accuracy of CMV information included on pregnancy-related websites and reference books, and (2) ...
De Beaudrap Pierre - - 2013
BACKGROUND: Malaria in pregnancy (MiP) is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. Because MiP is a complex phenomenon and malaria epidemiology is rapidly changing, additional evidence is still required to understand how best to control malaria. This study ...
Ata N - - 2013
Tularemia is a zoonotic infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. Although F. tularensis has been recognized as a human pathogen for a century, there are few reports regarding the occurrence of tularemia in pregnant women and its effect on the fetus; only seven ...
Zaietta Gabriel A - - 2013
Blastomycosis rarely presents in pregnancy. Pregnancy is a state of partial immunodeficiency that predisposes to blastomyces infection, especially in endemic areas. Blastomycosis in pregnancy has been reported in a few female patients and their offspring. We are reporting a 32-year-old pregnant patient at 34 weeks of gestation who presented with ...
Carr Shannon - - 2013
Adolescents may be ideal candidates for intrauterine device (IUD) use, given high rates of unintended pregnancy and less successful use of short-acting contraceptive methods. Concerns about elevated risks of pelvic inflammatory disease in adolescents, with the consequences of infertility, ectopic pregnancy, and pelvic pain, prevent many clinicians from inserting IUDs ...
Lehnen Harald - - 2013
The epidemic increase of type 2 diabetes and obesity in developed countries cannot be explained by overnutrition, physical inactivity and/or genetic factors alone. Epidemiologic evidence suggests that an adverse intrauterine environment, in particular a shortage or excess of nutrients is associated with increased risks for many complex diseases later in ...
Murphy Vanessa E - - 2013
ABSTRACT BACKGROUND: Respiratory viral infections are common in pregnancy, but their health impact, especially in asthma is unknown. The objective of the study was to assess the frequency, severity and consequences of respiratory viral infection in pregnancy in women with and without asthma. METHODS: In this prospective cohort study, common ...
Morgan Jamie - - 2013
Maternal sepsis is relatively common. Most of these infections are the result of tissue damage during labor and delivery and physiologic changes normally occurring during pregnancy. These infections, whether directly pregnancy-related or simply aggravated by normal pregnancy physiology, ultimately have the potential to progress to severe sepsis and septic shock. ...
Youssef Dima - - 2013
Blastomycosis rarely presents in pregnancy. Pregnancy is a state of partial immunodeficiency that predisposes to blastomyces infection, especially in endemic areas. Blastomycosis in pregnancy has been reported in a few female patients and their offspring. We are reporting a 32-year-old pregnant patient at 34 weeks of gestation who presented with ...
Silasi Michelle - - 2013
A role for microbial invasion leading to inflammation in the amniotic cavity and subsequent pre-term delivery has been well established. For years, the role of viral infections in pregnancy has been minimized and thought of as harmless, with a few exceptions. Recent evidence now encourages us to expand our thinking ...
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