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Hu Hui H Department of Epidemiology, College of Public Health and Health Professions, University of - - 2014
Hypertensive disorders of pregnancy (HDP, including gestational hypertension, preeclampsia, and eclampsia) have a substantial public health impact. Maternal exposure to high levels of air pollution may trigger HDP, but this association remains unclear. The objective of our report is to assess and quantify the association between maternal exposures to criteria ...
Jensen Et E National Institutes of Health, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, - - 2014
To evaluate whether hormonal contraceptives, used before or in early pregnancy, confer increased risk of preterm birth or reduced fetal growth. Population-based cohort study conducted by the Norwegian Institute of Public Health (Mother and Child Cohort Study, 1998-2008) with linkage to the Norwegian Prescription Registry and to the Medical Birth ...
Paterno Mary T - - 2014
To develop and test a comprehensive tool for measuring women's attitudes toward the possibility of becoming pregnant. Cross-sectional mixed methods study. Two obstetric/gynecologic (OB/GYN) clinics and one family planning clinic in Baltimore, Maryland. One-hundred thirty (130) nonpregnant, primarily African American women (84%) age 18 to 29. Participants completed a computer-based ...
Bloom Michael S - - 2014
Previous work suggests an increased risk for spontaneous pregnancy loss linked to high levels of inorganic arsenic (iAs) in drinking water sources (>10 mug/L). However, there has been little focus to date on the impact of low-moderate levels of iAs in drinking water (<10 mug/L). To address this data gap ...
Brandlistuen Ragnhild Eek RE Division of Mental Health, Norwegian Institute of Public Health, Oslo, Norway; Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, - - 2014
In a letter to the editor of Basic & Clinical Pharmacology & Toxicology, Per Damkier et al.(1) criticise recent studies linking paracetamol exposure in pregnancy with adverse neurodevelopmental outcomes. They state that the recent findings on associations between prolonged prenatal paracetamol exposure and adverse child developmental outcomes rely primarily on questionnaire-based ...
Dayan Natalie N Division of General Internal Medicine, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, - - 2014
Overweight and obese women may be heavy users of in vitro fertilization (IVF) owing to obesity-related oligo-anovulation. The higher doses of gonadotropins required to achieve pregnancy in obese women may contribute to impaired placentation and the development of preeclampsia. This study was designed to assess the combined effect of high ...
Crawford Giselle G Homerton Fertility Centre, Homerton University Hospital, London E96SR, - - 2014
There is a growing body of evidence surrounding the role played by seminal plasma in human implantation. Seminal fluid contains several proteins that interact with cervical and uterine epithelial cells inducing active immune tolerance. We sought to answer the study question: Does exposure to seminal plasma improve pregnancy outcomes in ...
Padula Amy M AM Stanford University, School of Medicine, Department of Pediatrics, Stanford, CA, - - 2014
Preterm birth is an important marker of health and has a prevalence of 12-13% in the U.S. Polycyclic aromatic hydrocarbons (PAHs) are a group of organic contaminants that form during the incomplete combustion of hydrocarbons, such as coal, diesel and gasoline. Studies suggest that exposure to PAHs during pregnancy is ...
Gy Rffy Zsuzsa - - 2014
There is a worldwide rising tendency of women deciding to become physicians; hence, one of the most remarkable fields of investigation is the wellbeing of female doctors. The aim of this study was to describe female physicians' reproductive health in Hungary and to explore the potential correlation between their reproductive ...
Kalugina Alla Stanislavovna AS Department of Women's Reproductive Health, North-Western State Medical University named after I.I.Mechnikov , St. Petersburg , Russia Federation - - 2014
Abstract The aim of this study was to compare the efficacy when using vitrified and fresh eggs depending on the applied controlled ovarian stimulation protocols in egg donation programs. Study results showed that the controlled ovarian stimulation protocol does not affect the outcome of IVF/ICSI. Vitrification provided survival and pregnancy ...
Gibbins Kj K University of Utah Health Sciences Center and Intermountain Healthcare Salt Lake City, UT, USA - - 2014
The presence of antiphospholipid antibodies is considered a risk factor for pre-eclampsia. Two meta-analyses and a number of case-control and cohort studies have found associations between pre-eclampsia and lupus anticoagulant, anticardiolipin, and/or anti-β2 glycoprotein I. However, existing literature is inconsistent, with varying severity of pre-eclampsia phenotype examined, differing aPL titer ...
Erez Azulay Carmit C Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, - - 2014
Abstract Objective: To investigate the association between anemia during pregnancy and subsequent future maternal cardiovascular morbidity and mortality. Methods: A retrospective cohort study was conducted, comparing women with and without anemia during pregnancy. Deliveries occurred during 1988-1998 and had followed for more than a decade. Incidence of long-term cardiovascular morbidity ...
Diesel J C JC Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, - - 2014
We examined the association between gestational weight gain (GWG) and offspring obesity at age 36 months. Mother-infant dyads (n = 609) were followed from a first study visit (mean [standard deviation]: 18.8 [2.7] weeks gestation) to 36 months postpartum. Total GWG over the entire pregnancy was defined as excessive or non-excessive according ...
Leibson Tom T 1Clinical fellow, Clinical pharmacology and Motherisk program 2Clinical pharmacology and toxicology resident, University of Toronto 3Department of Clinical pharmacology and toxicology, Hospital for Sick - - 2014
This TDM Journal Club aims to appraise the manuscript published by Munoz et al., (2014) and to debate its ability to inform clinical practice. The phase 1-2, randomized (ratio 2:1) double-blind controlled trial conducted by the authors from 2008 to 2012 included 48 pregnant women aged 18 to 45 years ...
Barrett Helen L - - 2014
Elevated maternal triglycerides have been associated with adverse pregnancy outcomes including an increased risk of preeclampsia and macrosomia. A valid triglyceride meter would allow the examination of maternal postprandial triglycerides in a systematic manner. A non-fasting venous and two capillary measurements (using the Roche Accutrend(R) Plus meter) of triglycerides were ...
Chudal Roshan R Department of Child Psychiatry, University of Turku, Turku, Finland. Electronic address: - - 2014
Prenatal smoking exposure affects fetal growth and development and is associated with increased risk of various neurodevelopmental disorders. Only one previous study has examined the association between maternal smoking during pregnancy and the risk of bipolar disorder (BPD). In this nested case control study derived from all singleton live births ...
Lim Soo Soo SS KPJ Penang Specialist Hospital, Seberang Jaya, Penang, - - 2014
The prevalence of hemorrhoids among pregnant women is high in late pregnancy. This study was to evaluate the efficacy between drug treatment with Procort (topical hydrocortisone cream 1%) and mechanical treatment with a Hai's Perianal Support (HPS) toilet seat device in managing symptomatic hemorrhoids during the third trimester of pregnancy. ...
Fisher Mandy M Health Canada, Ottawa, ON, - - 2014
Phthalates and bisphenol A (BPA) are high production volume and ubiquitous chemicals that are quickly metabolized in the body. Traditionally, studies have relied on single spot urine analyses to assess exposure; ignoring variability in concentrations throughout a day or over a longer period of time. We compared BPA and phthalate ...
Hui Amy Leung - - 2014
The objectives of this study were to assess the efficacy of lifestyle intervention on gestational weight gain in pregnant women with normal and above normal body mass index (BMI) in a randomized controlled trial. A total of 116 pregnant women (<20 weeks of pregnancy) without diabetes were enrolled and 113 ...
Falkegård Marit M Women's Health and Perinatology Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT- The Arctic University of Norway, - - 2014
To investigate the validity of self-reported information about hypertensive disorders in previous pregnancies among women participating in the 4(th) survey of the Tromsø Study. Retrospective cohort study with case-control design. Parous women participating in the 4(th) survey of the Tromsø Study. Medical records including partograms of 200 randomly selected women ...
Gammill Hilary S HS 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Obstetrics & Gynecology, University of Washington, Seattle, WA, - - 2014
Maternal-fetal cell exchange during pregnancy results in acquisition of microchimerism, which can durably persist in both recipients. Naturally acquired microchimerism may impact maternal-fetal interaction in pregnancy. We conducted studies to ask whether microchimerism that a woman acquired from her own mother is detectable before or during pregnancy in women with ...
Robledo-Aceves Mireya M Centro de Registro e Investigación sobre Anomalías Congénitas (CRIAC), Servicio de Genética y Unidad de Citogenética, División de Pediatría, Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, Jalisco, - - 2014
Mexico is recognized as a country with a high prevalence of gastroschisis, although the cause of this remains unclear. We define the prevalence and potential risk factors for gastroschisis in a public hospital from West México. A case-control study was conducted among 270 newborns, including 90 patients with nonsyndromic gastroschisis ...
Schmidt Rebecca J - - 2014
Iron deficiency affects 40%-50% of pregnancies. Iron is critical for early neurodevelopmental processes that are dysregulated in autism spectrum disorder (ASD). We examined maternal iron intake in relation to ASD risk in California-born children enrolled in a population-based case-control study (the Childhood Autism Risks from Genetics and the Environment (CHARGE) ...
Chen Ling-Wei - - 2014
BackgroundConsiderable controversy exists regarding the relation between maternal caffeine intake during pregnancy and risk of low birth weight (birth weight <2,500 g). We aim to assess this association using a systematic review and dose¿response meta-analysis of prospective studies.MethodsPotential articles were identified by searching MEDLINE and SCOPUS databases through 17 July 2013. ...
Kantsø Bjørn B Microbiological Diagnostics and Virology, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen, Denmark. Electronic address: - - 2014
The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to ...
Sabolovic Rudman Senka S Department of Gynecology and Obstetrics, University Hospital Sisters of Mercy, Zagreb, - - 2014
To determine platelet serotonin (5-HT) concentrations and genotype and allele frequencies of serotonergic type 2A receptor gene (HTR2A) and 5-HT transporter gene (SLC6A4) in women with pre-eclampsia, gestational hypertension without proteinuria (PIH) and in control normotensive pregnant women. The study included 96 control women, 131 women with PIH and 84 ...
van Dorp Wendy W Department of Gynaecology and Obstetrics, Division Reproductive Medicine, Erasmus MC-University Medical Centre Rotterdam, s'Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands; Department of Paediatric Oncology/Haematology, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands. Electronic address: - - 2014
To evaluate the maternal and neonatal outcome of non-anonymous oocyte donation compared to in vitro fertilization. Study design We compared 84 oocyte donation pregnancies with a 251 matched in vitro fertilization cohort. Maternal and neonatal outcomes were retrieved from a nationwide perinatal registry. Oocyte donation and in vitro fertilization pregnancies ...
Yeung Edwina H EH From the Epidemiology Branch (E.H.Y., J.L.M., C.Z., T.M., P.M.) and Biostatistics and Bioinformatics Branch (A.L.) in the Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD; Glotech, Inc, Rockville, MD (Z.L.); and Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.Y.T.). - - 2014
Copeptin, a surrogate biomarker of vasopressin, has been associated with renal function decline and may serve as a useful early biomarker for preeclampsia. We measured serum copeptin using samples collected longitudinally during pregnancy among unaffected controls (n=136) and cases of preeclampsia (n=169), gestational diabetes mellitus (n=92), gestational hypertension (n=101), and ...
Franck Ulrich U Helmholtz Centre for Environmental Research - UFZ, Core Facility 'Studies', Leipzig. - - 2014
Redecoration of dwellings is a common behavior of expecting parents. Former studies gave evidence that early childhood exposure to volatile organic compounds (VOC) resulting from renovation activities may increase the risk for wheeze in infants. The aim of the present study was to evaluate the impact of prenatal exposure on ...
Wöber Martina M Kinderwunschzentrum Goldenes Kreuz, Vienna, - - 2014
In azoospermia processing of the TESE material often results in a sample of reduced purity. This prospective study was set up to clarify whether a combination of enzymatic digestion, density gradient centrifugation and stimulation of motility (where indicated) is a feasible option in TESE patients. A total of 63 samples ...
Rubio Irene I Instituto Universitario IVI Valencia, University of Valencia, Valencia, - - 2014
To determine whether incubation in the integrated EmbryoScope time-lapse monitoring system (TMS) and selection supported by the use of a multivariable morphokinetic model improve reproductive outcomes in comparison with incubation in a standard incubator (SI) embryo culture and selection based exclusively on morphology. Prospective, randomized, double-blinded, controlled study. University-affiliated private ...
Huang Tianhua T Genetics Program, North York General Hospital, Toronto, Ontario, - - 2014
To assess the concentration of first and second trimester maternal serum markers in pregnancies with a vanishing twin. This is a retrospective case-control study of pregnancies screened for Down syndrome at one Ontario centre. Singleton pregnancies with ultrasound evidence of a vanishing twin were identified and each was matched with ...
Cândido da Silva Ageo Mário - - 2014
Although studies have shown an association between air pollutants from anthropogenic sources and pregnancy outcomes, little is known regarding the association between low birth weight (LBW) and exposure to emissions of biomass burning. This population-based retrospective cohort study assessed the effect of exposure to particulate matter and carbon monoxide (CO) ...
Gerosa Maria M University of Milan, Ospedale Gaetano Pini, Division of Rheumatology, Department of Clinical Sciences and Community Health , via Pini 9, 20122 Milan , Italy +390258296719 ; +390258296315 ; - - 2014
Introduction: In the past two decades, the number of women with autoimmune and inflammatory diseases experiencing a pregnancy has significantly increased in parallel with the enormous advances in the diagnosis and management of these disorders. However, information regarding the safety of immunosuppressive agents comes from case reports and case series ...
Andersen Jon Trærup JT Laboratory of Clinical Pharmacology, Copenhagen University Hospital Rigshospitalet, the Department of Clinical Pharmacology, Bispebjerg Hospital, the Mental Health Centre Copenhagen, and the Faculty of Health Sciences, University of Copenhagen, Copenhagen, - - 2014
To investigate whether exposure to selective serotonin reuptake inhibitors (SSRIs) in early pregnancy is associated with miscarriage. This was a nationwide cohort study identifying all registered pregnancies in Denmark from 1997 to 2010. All births were identified using the Medical Birth Registry, and all records of induced abortion or miscarriage ...
Francis Jenny J Department of Pediatrics, Division of Adolescent Medicine, Mount Sinai Adolescent Health Center, New York, New York. Electronic address: - - 2014
To examine the association between symptoms of depression and ambivalence about pregnancy in an inner-city adolescent female population. This study analyzed data from 220 urban minority adolescent females (ages, 15-19 years) presenting for contraceptive initiation in a comprehensive, free-of-cost, adolescent health center in New York City. Cross-sectional baseline data were examined ...
Vitorino Carvalho Anaïs A A Vitorino Carvalho, UMR 1198 BDR, INRA, Jouy-en-Josas, 78350, - - 2014
In mammals, Suppressor Of Cytokine Signalling (CISH, SOCS1 to SOCS7) factors control signalling pathways involved in the regulation of numerous physiological processes including pregnancy. In order to gain new insights into the biological functions of SOCS in the endometrium, a comprehensive analysis of SOCS gene expression was carried out in ...
Greenwood Darren C DC Division of Epidemiology and Biostatistics, School of Medicine, University of Leeds, Leeds, LS2 9JT, UK, - - 2014
Caffeine is commonly consumed during pregnancy, crosses the placenta, with fetal serum concentrations similar to the mother's, but studies of birth outcome show conflicting findings. We systematically searched Medline and Embase for relevant publications. We conducted meta-analysis of dose-response curves for associations between caffeine intake and spontaneous abortion, stillbirth, preterm ...
Jimenez-Solem Espen E Laboratory of Clinical Pharmacology, Rigshospitalet Department of Clinical Pharmacology, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark. - - 2014
Pharmacological treatment during pregnancy has been a huge challenge since the establishment of thalidomide´s teratogenicity in the early sixties. Analyses of possible risks associated with drug intake during pregnancy are not possible by performing randomized trials, and interspecies extrapolation is challenging. The best available method is through epidemiological studies. During ...
Smy Laura - - 2014
A healthy woman with mild to moderate asthma came to my clinic today after learning that she was pregnant. She inquired about continuing her inhaled corticosteroid (ICS) medication and whether there would be any risks to her unborn child if she were to do so. What would you advise? Given ...
Stanford Joseph B JB Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, - - 2014
The Creighton Model FertilityCare System (CrMS) teaches women to identify days when intercourse is likely to result in pregnancy. We sought to assess the impact of the CrMS on time to pregnancy (TTP), via per-cycle pregnancy rates (fecundability). We conducted a parallel randomised trial at the University of Utah School ...
Bakker Marloes M Department of Public and Occupational Health and EMGO Institute for Health and Care Research, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The - - 2014
The aim of this study was to investigate which prepartum determinants contribute to the development of postpartum (PP) fatigue among working women in the Netherlands. A prospective cohort study in 15 Dutch companies was conducted to measure different potential predictors using self-administrated questionnaires at baseline and at 30weeks of pregnancy. ...
Zhu Xiaoxia X Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, - - 2014
A growing body of evidence has investigated the association between maternal exposure to PM2.5 (particulate matter with aerodynamic diameter 2.5 μm) during pregnancy and adverse pregnancy outcomes. However, the results of those studies are not consistent. To synthetically quantify the relationship between maternal exposure to PM2.5 during pregnancy and pregnancy outcomes ...
Yazdy Mahsa M MM From the Slone Epidemiology Center, Boston University, Boston, - - 2014
Selective serotonin-reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. Previous studies have suggested that SSRIs may increase the risk of birth defects, including clubfoot. Using data from a population-based case-control study, we evaluated whether SSRI use increased the risk of clubfoot. Mothers were interviewed within 1 year after delivery ...
Park Young-Sun - - 2014
Abstract Aim: To examine how complex and irregular fetal heart rate (FHR) dynamics differ between fetuses of normal pregnancies and those of pregnancies complicated by maternal anemia (MA), and to place this in the context of high-risk pregnancies. Methods: Our study population consisted of 97 pregnant women affected by MA, ...
Parr M H MH Animal & Grassland Research & Innovation Centre, Teagasc, Mellows Campus, Athenry, Co. Galway, Ireland; School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, - - 2014
One of the main determining factors of pregnancy per artificial insemination (P/AI) is an optimum concentration of progesterone (P4) in the early luteal phase. This study examined the effects of P4 supplementation on P/AI in lactating Holstein-Friesian cows. A total of 453 cows in 8 spring-calving herds were used in ...
Larsen Ann Dyreborg AD National Research Centre for the Working Environment, Lersoe Parkallé 105, DK-2100 Copenhagen, Denmark. - - 2014
Few epidemiological studies have studied maternal stress exposure during pregnancy and odds of asthma and atopic dermatitis (AD) among offspring, and none have extended the focus to psychosocial job strain. The aim of this study was to assess the association between maternal job strain during pregnancy and asthma as well ...
Awwad J J Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, - - 2014
To determine whether 17 alpha-hydroxyprogesterone caproate (17OHPC) prolongs gestation beyond 37 weeks of gestation (primary outcome) and reduces neonatal morbidity (secondary outcome) in twin pregnancy. Randomised controlled double-blind clinical trial. Tertiary-care university medical centre. Unselected women with twin pregnancies. Participants received weekly injections of 250 mg 17OHPC (n = 194) or placebo (n = 94), from ...
Tandberg A A Department of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen, Norway; Department of Global Public Health and Primary Care, University of Bergen, Bergen, - - 2014
To examine the risk of pre-eclampsia (PE) in women conceiving after assisted reproductive technologies (ART). Potential confounding from maternal age, long intervals between births, new partner and smoking were evaluated. Population-based cohort study with data from the Medical Birth Registry of Norway. A total of 501 766 mothers with offspring from ...
Were Edwin O EO aDepartment of Reproductive Health, Moi University, Eldoret, Kenya bDepartment of Global Health, University of Washington, Seattle, Washington, USA cCentre for Clinical Research dCentre for Microbiology Research, Kenya Medical Research Institute eDepartment of Obstetrics and Gynecology, Kenyatta National Hospital, Nairobi, Kenya fDepartment of Medicine gDepartment of Epidemiology hDepartment of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA. *Members of the Partners PrEP Study Team are listed in the Acknowledgements - - 2014
There is a paucity of data on the effect of antiretroviral medications on male fertility. Couples affected by HIV-1 often have fertility intentions, and antiretroviral medications, as both treatment of HIV-1-infected persons and pre-exposure prophylaxis (PrEP) for uninfected persons, are part of peri-conception risk reduction. Within a randomized, placebo-controlled trial ...
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