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Franck Ulrich U Helmholtz Centre for Environmental Research - UFZ, Core Facility 'Studies', Leipzig. - - 2014
Redecoration of dwellings is a common behavior of expecting parents. Former studies gave evidence that early childhood exposure to volatile organic compounds (VOC) resulting from renovation activities may increase the risk for wheeze in infants. The aim of the present study was to evaluate the impact of prenatal exposure on ...
Wöber Martina M Kinderwunschzentrum Goldenes Kreuz, Vienna, - - 2014
In azoospermia processing of the TESE material often results in a sample of reduced purity. This prospective study was set up to clarify whether a combination of enzymatic digestion, density gradient centrifugation and stimulation of motility (where indicated) is a feasible option in TESE patients. A total of 63 samples ...
Rubio Irene I Instituto Universitario IVI Valencia, University of Valencia, Valencia, - - 2014
To determine whether incubation in the integrated EmbryoScope time-lapse monitoring system (TMS) and selection supported by the use of a multivariable morphokinetic model improve reproductive outcomes in comparison with incubation in a standard incubator (SI) embryo culture and selection based exclusively on morphology. Prospective, randomized, double-blinded, controlled study. University-affiliated private ...
Huang Tianhua T Genetics Program, North York General Hospital, Toronto, Ontario, - - 2014
To assess the concentration of first and second trimester maternal serum markers in pregnancies with a vanishing twin. This is a retrospective case-control study of pregnancies screened for Down syndrome at one Ontario centre. Singleton pregnancies with ultrasound evidence of a vanishing twin were identified and each was matched with ...
Cândido da Silva Ageo Mário - - 2014
Although studies have shown an association between air pollutants from anthropogenic sources and pregnancy outcomes, little is known regarding the association between low birth weight (LBW) and exposure to emissions of biomass burning. This population-based retrospective cohort study assessed the effect of exposure to particulate matter and carbon monoxide (CO) ...
Gerosa Maria M University of Milan, Ospedale Gaetano Pini, Division of Rheumatology, Department of Clinical Sciences and Community Health , via Pini 9, 20122 Milan , Italy +390258296719 ; +390258296315 ; - - 2014
Introduction: In the past two decades, the number of women with autoimmune and inflammatory diseases experiencing a pregnancy has significantly increased in parallel with the enormous advances in the diagnosis and management of these disorders. However, information regarding the safety of immunosuppressive agents comes from case reports and case series ...
Andersen Jon Trærup JT Laboratory of Clinical Pharmacology, Copenhagen University Hospital Rigshospitalet, the Department of Clinical Pharmacology, Bispebjerg Hospital, the Mental Health Centre Copenhagen, and the Faculty of Health Sciences, University of Copenhagen, Copenhagen, - - 2014
To investigate whether exposure to selective serotonin reuptake inhibitors (SSRIs) in early pregnancy is associated with miscarriage. This was a nationwide cohort study identifying all registered pregnancies in Denmark from 1997 to 2010. All births were identified using the Medical Birth Registry, and all records of induced abortion or miscarriage ...
Francis Jenny J Department of Pediatrics, Division of Adolescent Medicine, Mount Sinai Adolescent Health Center, New York, New York. Electronic address: - - 2014
To examine the association between symptoms of depression and ambivalence about pregnancy in an inner-city adolescent female population. This study analyzed data from 220 urban minority adolescent females (ages, 15-19 years) presenting for contraceptive initiation in a comprehensive, free-of-cost, adolescent health center in New York City. Cross-sectional baseline data were examined ...
Vitorino Carvalho Anaïs A A Vitorino Carvalho, UMR 1198 BDR, INRA, Jouy-en-Josas, 78350, - - 2014
In mammals, Suppressor Of Cytokine Signalling (CISH, SOCS1 to SOCS7) factors control signalling pathways involved in the regulation of numerous physiological processes including pregnancy. In order to gain new insights into the biological functions of SOCS in the endometrium, a comprehensive analysis of SOCS gene expression was carried out in ...
Greenwood Darren C DC Division of Epidemiology and Biostatistics, School of Medicine, University of Leeds, Leeds, LS2 9JT, UK, - - 2014
Caffeine is commonly consumed during pregnancy, crosses the placenta, with fetal serum concentrations similar to the mother's, but studies of birth outcome show conflicting findings. We systematically searched Medline and Embase for relevant publications. We conducted meta-analysis of dose-response curves for associations between caffeine intake and spontaneous abortion, stillbirth, preterm ...
Jimenez-Solem Espen E Laboratory of Clinical Pharmacology, Rigshospitalet Department of Clinical Pharmacology, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark. - - 2014
Pharmacological treatment during pregnancy has been a huge challenge since the establishment of thalidomide´s teratogenicity in the early sixties. Analyses of possible risks associated with drug intake during pregnancy are not possible by performing randomized trials, and interspecies extrapolation is challenging. The best available method is through epidemiological studies. During ...
Smy Laura - - 2014
A healthy woman with mild to moderate asthma came to my clinic today after learning that she was pregnant. She inquired about continuing her inhaled corticosteroid (ICS) medication and whether there would be any risks to her unborn child if she were to do so. What would you advise? Given ...
Stanford Joseph B JB Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, - - 2014
The Creighton Model FertilityCare System (CrMS) teaches women to identify days when intercourse is likely to result in pregnancy. We sought to assess the impact of the CrMS on time to pregnancy (TTP), via per-cycle pregnancy rates (fecundability). We conducted a parallel randomised trial at the University of Utah School ...
D'Onofrio Brian M BM Indiana University-Bloomington, Department of Psychological and Brain - - 2014
The Developmental Origin of Health and Disease (DOHaD) hypothesis is a broad theoretical framework that emphasizes how early risk factors have a causal influence on psychopathology. Researchers have raised concerns about the causal interpretation of statistical associations between early risk factors and later psychopathology because most existing studies have been ...
Morón-Duarte Lina Sofía LS Centro de Investigaciones en Ciencias de la Salud, Universidad del Rosario, Bogotá, Bogotá, Colombia, - - 2014
To identify risk factors for adolescent pregnancy among female students in Bogotá, Colombia This was a retrospective study of cases and controls matched by age, identified by means of a survey on the sexual behavior of adolescent students in Bogotá (Encuesta sobre el Comportamiento Sexual de los Adolescentes Escolarizados en ...
Bakker Marloes M Department of Public and Occupational Health and EMGO Institute for Health and Care Research, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The - - 2014
The aim of this study was to investigate which prepartum determinants contribute to the development of postpartum (PP) fatigue among working women in the Netherlands. A prospective cohort study in 15 Dutch companies was conducted to measure different potential predictors using self-administrated questionnaires at baseline and at 30weeks of pregnancy. ...
Zhu Xiaoxia X Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, - - 2014
A growing body of evidence has investigated the association between maternal exposure to PM2.5 (particulate matter with aerodynamic diameter 2.5 μm) during pregnancy and adverse pregnancy outcomes. However, the results of those studies are not consistent. To synthetically quantify the relationship between maternal exposure to PM2.5 during pregnancy and pregnancy outcomes ...
Yazdy Mahsa M MM From the Slone Epidemiology Center, Boston University, Boston, - - 2014
Selective serotonin-reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. Previous studies have suggested that SSRIs may increase the risk of birth defects, including clubfoot. Using data from a population-based case-control study, we evaluated whether SSRI use increased the risk of clubfoot. Mothers were interviewed within 1 year after delivery ...
Park Young-Sun - - 2014
Abstract Aim: To examine how complex and irregular fetal heart rate (FHR) dynamics differ between fetuses of normal pregnancies and those of pregnancies complicated by maternal anemia (MA), and to place this in the context of high-risk pregnancies. Methods: Our study population consisted of 97 pregnant women affected by MA, ...
Parr M H MH Animal & Grassland Research & Innovation Centre, Teagasc, Mellows Campus, Athenry, Co. Galway, Ireland; School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, - - 2014
One of the main determining factors of pregnancy per artificial insemination (P/AI) is an optimum concentration of progesterone (P4) in the early luteal phase. This study examined the effects of P4 supplementation on P/AI in lactating Holstein-Friesian cows. A total of 453 cows in 8 spring-calving herds were used in ...
Larsen Ann Dyreborg AD National Research Centre for the Working Environment, Lersoe Parkallé 105, DK-2100 Copenhagen, Denmark. - - 2014
Few epidemiological studies have studied maternal stress exposure during pregnancy and odds of asthma and atopic dermatitis (AD) among offspring, and none have extended the focus to psychosocial job strain. The aim of this study was to assess the association between maternal job strain during pregnancy and asthma as well ...
Awwad J J Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, - - 2014
To determine whether 17 alpha-hydroxyprogesterone caproate (17OHPC) prolongs gestation beyond 37 weeks of gestation (primary outcome) and reduces neonatal morbidity (secondary outcome) in twin pregnancy. Randomised controlled double-blind clinical trial. Tertiary-care university medical centre. Unselected women with twin pregnancies. Participants received weekly injections of 250 mg 17OHPC (n = 194) or placebo (n = 94), from ...
Tandberg A A Department of Gynaecology and Obstetrics, Haukeland University Hospital, Bergen, Norway; Department of Global Public Health and Primary Care, University of Bergen, Bergen, - - 2014
To examine the risk of pre-eclampsia (PE) in women conceiving after assisted reproductive technologies (ART). Potential confounding from maternal age, long intervals between births, new partner and smoking were evaluated. Population-based cohort study with data from the Medical Birth Registry of Norway. A total of 501 766 mothers with offspring from ...
Were Edwin O EO aDepartment of Reproductive Health, Moi University, Eldoret, Kenya bDepartment of Global Health, University of Washington, Seattle, Washington, USA cCentre for Clinical Research dCentre for Microbiology Research, Kenya Medical Research Institute eDepartment of Obstetrics and Gynecology, Kenyatta National Hospital, Nairobi, Kenya fDepartment of Medicine gDepartment of Epidemiology hDepartment of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA. *Members of the Partners PrEP Study Team are listed in the Acknowledgements - - 2014
There is a paucity of data on the effect of antiretroviral medications on male fertility. Couples affected by HIV-1 often have fertility intentions, and antiretroviral medications, as both treatment of HIV-1-infected persons and pre-exposure prophylaxis (PrEP) for uninfected persons, are part of peri-conception risk reduction. Within a randomized, placebo-controlled trial ...
Hiersch Liran L Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Gestational diabetes mellitus (GDM) complicates 3-15% of pregnancies depending upon the geographic location and ethnic groups, and its incidence is estimated to increase even further due to the increasing rates of obesity in the general population and the trend towards advanced maternal age in pregnancy. GDM is associated with adverse ...
Gaskins Audrey J AJ From the Departments of Nutrition (AJG, MWG, and JEC), Epidemiology (AJG, JWR-E, RH, PLW, SAM, and JEC), Environmental Health (RH), and Biostatistics (PLW), Harvard School of Public Health, Boston, MA; the Channing Division of Network Medicine (JWR-E, SAM, and JEC) and Connors Center for Women's Health and Gender Biology (JWR-E), Department of Medicine, and the Department of Obstetrics, Gynecology, and Reproductive Biology (SAM), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; the Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA (MWG); the Department of Obstetrics, Gynecology and Reproductive Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA (AP); and Boston In Vitro Fertilization, Waltham, MA - - 2014
Two previous case-control studies observed associations between specific food groups and risk of miscarriage; however, to our knowledge, no previous studies have investigated dietary patterns and risk of pregnancy loss. We aimed to assess prepregnancy adherence to the alternate Healthy Eating Index 2010 (aHEI-2010), alternate Mediterranean diet (aMED), and Fertility ...
Mills James L JL From the Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development (JLM, RF, AL, and YW), and Genome Technology Branch, National Human Genome Research Institute (LCB), NIH, Bethesda, MD; the Department of Clinical Science, University of Bergen and Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); the Health Research Board of Ireland, Dublin, Ireland (PNK); the University of California, Berkeley, Berkeley, CA (BS); and the Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland - - 2014
Low maternal choline intake and blood concentration may be risk factors for having a child with a neural tube defect (NTD); however, the data are inconsistent. This is an important question to resolve because choline, if taken periconceptionally, might add to the protective effect currently being achieved by folic acid. ...
Sun Yuelian Y Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, - - 2014
Studies on the safety of drugs used during pregnancy are necessary and important but prone to bias. Using cases as their own controls can reduce bias. We used a case-crossover design and a case-time-control design to estimate the risk of congenital malformation (CM) for children born to mothers who redeemed ...
Morrell J M JM Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden. Electronic address: - - 2014
A successful outcome after artificial insemination with cooled semen is dependent on many factors, the sperm quality of the ejaculate being one. Previous studies have shown that spermatozoa with good motility, normal morphology, and good chromatin integrity can be selected by means of colloid centrifugation, particularly single layer centrifugation (SLC) ...
Xiang Lan L Reproductive Medicine Center, The First Affiliated Hospital of Anhui Medical University, Hefei, - - 2014
In this study, the clinical significance of first-trimester intrauterine haematomas (IUH) detected in pregnancies achieved by IVF-embryo transfer (IVF-ET) was evaluated. A retrospective case-control study was designed to compare obstetric and perinatal outcomes of 350 pregnancies with IUH and 350 matched controls without IUH. The incidence of first-trimester IUH detected ...
Wennberg Anna Lena AL Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden; Department of Nursing, Umeå University, Umeå, Sweden. Electronic address: - - 2014
By enhancing maternal nutritional status, midwives can help women lower the risks of pregnancy complications and adverse birth outcomes as well as improve maternal health during pregnancy and in the long run. Dietary counselling is, on the other hand, not reported to be effective. Poor communication and conflicting messages are ...
Nwagha U U Department of Obstetrics and Gynecology, College of Medicine, University of Nigeria, Enugu Campus, Nsukka, Nigeria ; Department of Physiology, Pulmonary Medicine Unit, College of Medicine, University of Nigeria, Enugu Campus, Nsukka, - - 2014
Forced expiratory volume in 6 s (FEV6) and FEV1/FEV6 ratio have traditionally been used as a surrogate for forced vital capacity (FVC) and FEV1/FVC in the assessment of spirometric lung function in nonpregnant subjects. However, the existence of this relationship during pregnancy is yet to be ascertained. The aim of ...
Yousefian Elham E Department of Midwifery, Islamic Azad University Falavarjan Branch, Isfahan, IR - - 2014
Recurrent pregnancy loss (RPL) is a serious problem for pregnancy. There is evidence that vascular complications play a principal role in RPL. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Polymorphisms (C677T, A1298C) of MTHFR gene are associated with decreased MTHFR activity. The aim of this study was ...
Goyal Lajya Devi LD Department of Obstetrics & Gynecology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab - - 2014
The study was carried out to investigate the prevalence, risk factors, and Pregnancy outcome in anti-HCV-positives pregnant women admitted for delivery in the Department of Obstetrics & Gynecology of Guru Gobind Singh Medical College and Hospital, Faridkot between January 2010 and January 2013. Department of obstetrics and Gynaecology of GGS ...
Kurlak Lesia O LO Department of Obstetrics and Gynaecology, School of Medicine, University of Nottingham, City Hospital Nottingham, - - 2014
Discussion continues as to whether de novo hypertension in pregnancy with significant proteinuria (pre-eclampsia; PE) and non-proteinuric new hypertension (gestational hypertension; GH) are parts of the same disease spectrum or represent different conditions. Non-pregnant hypertension, pregnancy and PE are all associated with oxidative stress. We have established a 6 weeks ...
Christofides Nicola J NJ School of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; - - 2014
Although teenage pregnancies in South Africa have declined, the short and longer term health and social consequences are a potential public health concern. This longitudinal study aimed to describe the range of risk and protective factors for incident unwanted and unplanned pregnancies occurring over 2 years of follow-up among a ...
Tehrani Hatave Ghasemi HG Department of Obstetrics and Gynecology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, - - 2014
Studies have shown significant correlation between time to pregnancy (TTP) and pregnancy outcomes. But understanding of these mechanisms may not be facilitated. The aim of this study was to determine the relation between TTP and pregnancy outcome. This study was a case cohort study that was done in Shahid Beheshti ...
Carwile Jenny L - - 2014
Prenatal drinking water exposure to tetrachloroethylene (PCE) has been previously related to intrauterine growth restriction and stillbirth. Pathophysiologic and epidemiologic evidence linking these outcomes to certain other pregnancy complications, including placental abruption, preeclampsia, and small-for-gestational-age (SGA) (i.e., ischemic placental diseases), suggests that PCE exposure may also be associated with these ...
Miyagawa Kazuya K Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, - - 2014
We herein report two cases of pregnant women who had chronic hypertension caused by renovascular hypertension due to multiple intrarenal microaneurysms from unknown causes, who had similar clinical courses. During the first pregnancy, both women developed uncontrollable severe hypertension that finally led to superimposed preeclampsia; however, during the second pregnancy, ...
Jayaprakasan Kannamannadiar K Division of Child Health, Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK Nottingham University Research and Treatment Unit in Reproduction (NURTURE), Queen's Medical Centre, University of Nottingham, Nottingham, UK Derby Fertility Unit, Royal Derby Hospital, Derby, - - 2014
Dehydroepiandrosterone (DHEA) has been proposed to improve pregnancy rates in women with diminished ovarian reserve undergoing in vitro fertilisation (IVF) treatment. However, evidence regarding its efficacy is supported by a limited number of randomised controlled trials (RCTs). This double-blinded RCT aims to measure the effect of DHEA supplementation prior to ...
Zhou Yanfeng Y Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan, P. R. - - 2014
The prevalence of childhood leukemia is increasing rapidly all over the world. However, studies on maternal benzene exposure during pregnancy and childhood acute lymphoblastic leukemia (ALL) have not been systematically assessed. Therefore, we performed a meta-analysis to investigate the association between maternal solvent, paint, petroleum exposure, and smoking during pregnancy ...
Lau Erica Y EY Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, - - 2014
Objectives. To systematically review the evidence from prospective and retrospective cohort studies on the association between gestational weight gain (GWG) and offspring's body weight. Methods. Electronic databases PubMed, Web of Science, CINAHL, and Academic Search Premiere were searched from inception through March 18, 2013. Included studies (n = 23) were ...
Barnado April A Division of Rheumatology, Department of Medicine , Medical University of South Carolina , Charleston, South Carolina , - - 2014
In a study of Gullah African-Americans, we compared pregnancy outcomes before and after systemic lupus erythematosus (SLE) diagnosis to controls to test whether there is a predisease state that negativelyaffects pregnancy outcomes. Cases and controls reporting at least one pregnancy were included. Controls were all Gullah African-American females. We collected ...
Whitfield Thomas T Infectious Diseases, North Manchester General Hospital, University of London, Manchester, - - 2014
Introduction: Despite plasma levels of certain HIV drugs decreasing in the third trimester of pregnancy there is no definitive evidence that therapeutic drug monitoring (TDM) improves HIV control and prevents mother-to-child transmission (MTCT). Indeed "one-off" TDM measurements are thought to poorly correlate with overall drug exposure [1]. We aim to ...
Grarup Pernille A PA Department of Pulmonary Medicine, Hvidovre Hospital, Hvidovre, - - 2014
Asthma and tobacco exposure is common among pregnant women. We investigated the effect of passive and active smoking on asthma control during pregnancy. Prospective observational design. Patients had their asthma control, based on symptoms, use of medication, spirometry, and exhaled nitric oxide [FENO], assessed every four weeks during 2nd and ...
Rosen Hadar - - 2013
Abstract Objective: To evaluate uterine activity during the third stage of labor and compare it to that observed in the second stage of labor. Study Design: Uterine electric activity was prospectively measured using electrical uterine myography (EUM) in 44 women with singleton pregnancy at term during the final 30 minutes ...
Yao Wei - - 2013
Recent advancements in fetal surgery have proven that tracheal occlusion in fetuses with congenital diaphragmatic hernia is an effective way to prevent the occurrence of pulmonary hypoplasia. A novel flexible fetoscope with a parallel mechanism structure of a thumbstick to carry on the fetal tracheal balloon occlusion by the targeting ...
Stanback John J FHI 360 , Research Triangle Park, NC , - - 2013
In many countries, pregnancy tests are not freely available in family planning clinics. As a result, providers sometimes deny services to non-menstruating clients due to uncertainty about pregnancy. Few clients are actually pregnant, yet denied clients run the risk of becoming pregnant, and those sent to pharmacies pay inflated prices ...
Engeland Anders A Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway. - - 2013
We aimed to explore associations between drugs dispensed to the father prior to conception and pregnancy outcomes, such as pre-term birth, perinatal mortality, foetal growth retardation and birth defects. In this cohort study, two population-based registries, the Medical Birth Registry of Norway and the Norwegian Prescription Database, were linked. The ...
Koteff Justin J ViiV Healthcare, Research Triangle Park, North Carolina, - - 2013
Dolutegravir (DTG; S/GSK1349572) is under clinical development as a once daily, unboosted integrase inhibitor for the treatment of HIV infection. The effect of DTG on glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and creatinine clearance (CLcr ) was evaluated in 34 healthy volunteers. Subjects received DTG 50 mg (once ...
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