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Results 401 - 450 of 472
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Vost D A - - 1978
A series of 100 successive amniocenteses performed on rural patients with high-risk pregnancies is described. The shake test was found to correlate well with gestational age as well as with fetal lung maturity, a practical point of importance in areas without facilities for estimating the lecithin/sphingomyelin (L/S) ratio. While the ...
van Bogaert L J - - 1978
A series of 52 placentas from the 36th week of gestation up to post-maturity was studied. The amniotic epithelium was studied with special regard to the morphological signs of maturation known to occur during this period. The results of the dating were compared with the presumed clinical age of the ...
O'Grady J P - - 1978
A mature lowland gorilla (Gorilla gorilla) in the Los Angeles Zoo had destroyed 3 successive infants. To avoid a recurrence, active intervention was instituted during its 4th pregnancy. The period of gestation was estimated by physical examination, radiography, and amniocentesis. Intrauterine growth was followed by serial ultrasonographic cephalometry. When fetal ...
Gunston K D - - 1978
The amniotic fluid of 250 patients in the third trimester of pregnancy was examined for surfactant content by means of the bubble test and total phospholipid estimation. No evidence was found that intra-uterine growth retardation accelerates pulmonary maturity in the fetus, and the finding of early pulmonary maturity does not ...
Robertson E G - - 1978
Maturity studies are reported on 204 women with high-risk pregnancies. Estimates of fetal maturity were made prenatally by the use of ultrasonic measurements, the lecithin/sphingomyelin (L/S) ratio, and a gestational index based on amniotic fluid creatinine, urea nitrogen, and cytology. These estimates were compared with the neonatal pediatric estimate of ...
Railsback K P - - 1978
The literature suggests that the presence of cellular debris and sediment in amniotic fluid samples may alter the value of the lecithin/sphingomyelin (L/S) ratios, with a loss of as much as 75 percent of the surface-active lecithin1 and consequently a marked change in the L/S ratio. We wish to report ...
Curbelo V - - 1978
Although increased concentrations of total lecithin in amniotic fluid allow prenatal assessment of fetal lung maturation, it has become clear that routine use of the L/S index may lead to a substantial number of inaccurate predictions. Since disaturated lecithin (DL) is a more specific marker of pulmonary surfactant than total ...
Hutchins C J - - 1978
The estriol/creatinine ratio was determined in a first morning urine sample in 1808 pregnancies in the 32nd week of gestation. The ratio obtained correlated closely with birthweight and showed a linear increase with percentile birthweight group. There was a 25-fold increase in perinatal mortality in those pregnancies with a ratio ...
Murphy B E - - 1978
While recent studies suggest that cortisol plays a role in lung maturation, conflicting reports have recently appeared relating cortisol in amniotic fluid to indices of lung maturation. the variation in the levels and differences in correlation appear to be due to differences in methodology, principally with respect to cross-reactivity in ...
Hertz R H - - 1978
Reliable knowledge of the duration of pregnancy prior to birth is often of crucial importance in making obstetric care decisions. Laboratory methods for estimating fetal maturity have received considerable attention, but the usefulness of historical information has only rarely been addressed. In order to examine the value of clinical estimators ...
Leader L - - 1978
A successful outcome of haemodialysis in a pregnant patient with chronic glomerulonephritis is reported. After a stable period of 9 years, pregnancy resulted in a definite deterioration of renal function. The importance of establishing biological maturity in preference to gestational maturity is stressed.
Newell-Morris L - - 1978
The appearance of the secondary centers of ossification was investigated in hand and foot radiographs of 112 fetal and neonatal Macaca nemestrina and a maturational index calculated using a scoring system that differentiated between the initial and later stages of ossification. Cumulative incremental curves of skeletal maturation, constructed by plotting ...
Woodman D D - - 1978
Amniotic fluid lecithin to sphingomyelin ratio (L/S) and adrenaline concentration, noradrenaline concentration, and noradrenaline to adrenaline ratio (NA/A) were measured in 50 normal women late in pregnancy. Between gestation weeks 37 and 43 the maturity-linked increase in L/S ratio was accompanied by similar increases in NA/A ratio and noradrenaline but ...
Hindson J C - - 1978
Measurements of factors involved in the degree of traction exerted during obstetric cases were carried out. Bovine material force was approximately 150 lbs. Maximum manual effort would be approximately four times this and mechanical traction would be at least 50 per cent higher again. A workable maternal fetal ratio was ...
Tchobroutsky C - - 1978
A total of 228 determinations of L/S ratios were performed in 132 insulin-dependent diabetic pregnancies. A declining L/S ratio was observed in 6 per cent of the cases without adverse effects on the fetus. No significant difference in the percentage of mature L/S ratios by weeks of pregnancy was found ...
Kotas R V - - 1978
Intra-amniotic betamethasone (6 mg.) given to six immature fetal baboons, at four and again at three days prior to delivery by cesarean section, between 147 and 158 days' gestation (term = 180 days), significantly increased the amniotic fluid lecithin/sphingomyelin (L/S) ratio. At delivery, treated animal lungs were more mature in ...
Ramzy I - - 1978
A cross sectional retrospective study of 400 cases of amniocentesis was performed to evaluate the reliability of using fetal fat staining cells as a method for assessment of fetal age and maturity. A sharp rise in the percentage of these cells in amniotic fluid occurred after 37 weeks of gestation ...
Mashiach S - - 1978
Following preliminary results in animal studies demonstrating that thyroxine (T4) injected directly into the fetus or the amniotic sac is capable of enhancing fetal lung maturity, a trial of thyroxine treatment in mean was carried out. Two hundred micrograms of T4 were injected intra-amniotically in eight women with high-risk pregnancies ...
Peleg D - - 1978
The role of fetal adrenals in the maturation of fetal lungs is not clear as yet. The anencephalic baby, with rudimentary adrenal glands, may be considered an excellent model for the study of this subject. The maturation of fetal lungs was determined in 3 anencephalic monsters and in 2 microencephalic ...
Spellacy W N - - 1978
Fetal head biparietal (BP) measurements by ultrasonic techniques and amniotic fluid lecithin-sphingomyelin (L/S) ratios were simultaneously determined (within 2 days) on 84 occasions in 72 women. Using the criteria for maturity of an L/S ratio of 2.0 or more or a BP measurement of 9.0 cm or more, there was ...
Cherayil G D - - 1977
Lecithin/sphingomyelin ratio (L/S ratio) in amniotic fluid has gained wide clinical acceptance as an index of fetal lung maturity. We determined L/S ratios of amniotic fluids centrifuged at various "g-forces." Our studies demonstrate that the L/S ratio value is highly dependent on the g-force used to prepare the fluid. We ...
Gosselin L - - 1977
Treatment of human amniotic fluid lipids dissolved in a chloroform/methanol (9:1, v/v) mixture by batchwise addition of diethylaminoethyl cellulose in a dry state proved to be an easy and rapid procedure for the removal of the acidic phospholipids which may interfere in the photodensitometric evaluation of the lecithin: spingomyelin ratio ...
Johnson L W - - 1977
The presence of fetal lung surfactant in amniotic fluid is indicative that fetal lungs are sufficiently mature for delivery without subsequent respiratory distress. However, current methods for detecting surfactant fail to positively distinguish saturated phosphatidylcholine (primarily dipalmitoyl phosphatidlycholine) from the many similar phosphatidylcholines also present in amniotic fluid. As a ...
Weinstein D - - 1977
Amniocenteses were performed in 73 pregnant women for maturity assessment in cases of high risk pregnancies, pregnancies of unknown gestational age and before an elective cesarean section. The evaluation of fetal maturity was based on: 1) foam test; 2)amniotic fluid cytology; 3)creatinine concentration; 4) fetography and 5) clinical criteria. The ...
Masood S - - 1977
Sixty samples of amniotic fluid were analyzed for their surfactant level by measuring the lecithin-spingomyelin ratio and performing the "shake" test. Cytologic examination of the sediment was also performed using Nile blue sulfate staining. The lecithin-sphingomyelin ratio was found to be the best method to predict fetal maturity and assess ...
Gabbe S G - - 1977
The amniotic fluid lecithin/sphingomyelin (L/S) ratio was determined in 182 pregnancies complicated by Classes B and C diabetes and in 28 patients with Classes D, F, and R diabetes. These data were retrospectively correlated with the occurrence of the respiratory distress syndrome (RDS) or hyaline membrane disease (HMD). Only four ...
Goldkrand J W - - 1977
The surface tension (ST)-lowering properties of an amniotic fluid lipid extract can provide a rapid and reliable means of predicting pulmonary maturity. One hundred and eleven samples from 91 patients were analyzed. A surface tension of less than 56 dynes per centimeter at 120 microliter of extract and less than ...
Whittle M J - - 1977
Serial samples of amniotic fluid were taken from 48 patients during labour. The lecithin/sphingomyelin (L/S) ratio was estimated and found to rise in 52 per cent, remain almost unchanged in 33 per cent and fall in 15 per cent. The rate of rise in the L/S ratio seemed inversely related ...
Spellacy W N - - 1977
Transabdominal amniocenteses were performed on both sacs of 14 sets of twins. In each instance one sac was marked with methylene blue to correctly identify the fluids. The lecithin/sphingomyelin ratio was determined on each fluid, and the correlation coefficient between the two sets of fluids was 0.86. There was no ...
Yaffe H - - 1977
THe thromboplastic activity of amniotic fluid was correlated with the lecithin sphingomyelin (L/S) ratio in 59 pregnancies. It was shown that the thromboplastic activity and the L/S ratio in amniotic fluid had a coefficient of correlation of r = --0-73 (P less than 0-004). The thromboplastic activity was estimated by ...
Gewolb I H - - 1977
Amniotic fluid cortisol (AFC) levels were measured in 76 normal and 67 high-risk human pregnancies. When compared to normal gestations, diabetic pregnancies were found to be associated with lower AFC levels, while toxemic, early Rh-sensitized, and other stressed pregnancies had higher mean cortisol values. Serially followed normal and high-risk pregnancies ...
Gewolb I H - - 1977
Amniotic fluid cortisol concentration was compared with lecithin/sphingomyelin ratio, gestational age, and eventual birth-weight in a large series of normal and high-risk human pregnancies in an effort to determine whether cortisol could be used as a reliable indicator of fetal maturity. It appears that when used alone amniotic fluid cortisol ...
Caritis S N - - 1977
Betamethasone was administered to six rhesus-sensitized pregnant women carrying seven fetuses in an attempt to accelerate fetal pulmonary maturation. A reduction in optical density of amniotic fluid at 450 mmu was observed in all cases following steroid therapy; however, only minimal changes were noted in the lecithin-sphingomyelin ratio. The implications ...
Morrison J C - - 1977
The efficacy of correlating the L/S ratio in the amniotic fluid with fetal lung maturity has been substantiated in normal pregnancies. In gestations complicated by fetomaternal diseases, however, the assay is less reliable. This study involves 555 pregnancies in which there was a significant maternal, fetal, or placental disorder. The ...
Harrison R F - - 1977
The reliability of eight methods for estimating gestational age in the third trimester of pregnancy has been assessed in patients with fetuses of known maturity. Late ultrasound cephalometry, amniotic fluid creatinine estimations and lecithin/sphingomyelin ratio were found to be significantly more reliable than the other five methods. The mean of ...
Skjaeraasen J - - 1977
In a material of 144 samples of amniotic fluid from the last trimester, creatinine concentration, lecithin/sphingomyelin (L/S) ration and their correlation, have been examined. Amniotic fluid creatinine concentration (a.f.c.) increased gradually through the last trimester up to 39 weeks (273-279 days p.m.) with median values of 2 mg/100 ml at ...
Akhter M S - - 1977
The amniotic fluid study of 80 samples from 40 patients, obtained by amniocentesis between 28 and 40 weeks of pregnancy, was carried out. It was noted that L/S (Lecithin/Sphingomyelin) ratio was significantly different at 36-38 weeks of pregnancy when compared with values in pregnancies of less than 36 weeks gestation ...
Morrison J C - - 1977
The lecithin-sphingomyelin (L/S) ratio is acknowledged to be superior to most procedures for predictinf fetal lung maturity in normal pregnancy. In complicated gestations, however, errors have been reported. This study involves 686 normal gestations and 389 pregnancies complicated by fetomaternal diseases. The L/S ratio, creatinine level, and percent of fat-staining ...
Schneider H - - 1976
The ultrastructure of neuroglial fatty metamorphosis (GFM) has been investigated in the telencephalic white matter of 12 premature and mature infants (gestational age 22-40 weeks; survival 0-96 days). GFM was found in all cases apart from a 22-week-old fetus, and involves predominantly astrocytic cells (68.8%), then glioblasts (43.5%), but only ...
Liggins G C - - 1976
In various organs in fetal animals, maturation is inducible by corticosteroids and delayed by hypophysectomy. A surge of corticosteroid in the fetal circulation preceding parturition may cause rapid organ maturation and enhanced viability. Since this phase of accelerated maturation is linked to the parturitional mechanisms, the changes can be termed ...
Fabro S - - 1976
The chief obstetrical problems encountered today in the prenatal evaluation of the high-risk fetus are presented. Advantages and pitfalls or recent techniques utilized in the management of the high-risk pregnancy are discussed. They include: a prenatal scoring system for identifying the high-risk population; examination of the karyotype of cells in ...
Suganuma T - - 1976
The action of Taka-amylase A from Asp. oryzae was studied quantitatively by the product analysis method using unlabeled maltotriose and maltotriose labeled at the reducing end as substrates. It was found that the ratio of the unlabeled products, maltose (G2) and glucose (G1) exceeded unity, and that the ratio of ...
Tan S Y - - 1976
A specific and thoroughly validated competitive protein binding radioassay has been developed for the measurement of unconjugated cortisol in human amniotic fluid. Cortisol levels rose throughout normal gestation from 8.6 +/- 0.8 ng/ml at less than 20 weeks to 19.8 +/- 1.5 ng/ml at 30-40 weeks. Levels were significantly higher ...
Hallman M - - 1976
The minor phospholipids in amniotic fluid from normal pregnancies were correlated with the well-established index of lung maturity, the lecithin/sphingomyelin (L/S) ratio. When the L/S ratio was less than 1.0, the acidic phospholippids phosphatidylglycerol (PG) and phosphatidylinositol (PI) were absent or low in concentration (0.0 to 2.5 per cent of ...
Doran T A - - 1976
Amniotic fluid creatinine, percentage of lipid-positive cells, and L/S ratio were determined on 285 samples from normal pregnancies and 222 samples from abnormal pregnancy states (Rh isoimmunization, diabetes, hypertensive disorders, intrauterine growth retardation, and hydramnios). In normal pregnancy the coefficient of correlation between true gestational age and estimated period of ...
Yedgar S - - 1976
Mixed dispersions of the nonionic detergent Triton X-100 and sphingomyelin were used as substrate for sphingomyelinase of rat brain. The dependence of the rate of hydrolysis on the concentration of sphingomyelin was measured in two ways: at a fixed concentration of Triton X-100 or at varying concentrations of this detergent, ...
Epstein M F - - 1976
The amniotic fluid lecithin/sphingomyelin (L/S) ratio in normal rhesus monkey pregnancies exhibits a distribution through the latter half of gestation similar to that seen in human pregnancies. Changes in the synthesis and concentration of lecithin in the fetal lung, measured both in vitro and in vivo, are paralleled by changes ...
Sims C D - - 1976
The lecithin/sphingomyelin (L/S) ratio has been estimated in the amniotic fluid from 20 patients with a twin pregnancy. The values in each pair of amniotic fluids were closely related. If amniotic fluid from one sac only is available, it is suggested that a ratio of 2-5:1 is taken as the ...
Krieglsteiner P - - 1976
118 samples of amniotic fluid were taken from 102 patients in the 25th to the 43th week of pregnancy by amniotomy or by transabdominal amniocentesis. 76 samples were obtained from patients with normal pregnancies without evidence for either induction or retardation of lung maturity; they served to establish normal values. ...
Löfstrand T - - 1976
176 samples of amniotic fluid were obtained by abdominal amniocentesis from 69 women with complicated pregnancies (toxemia, diabetes mellitus or rhesus isoimmunization) in the 27th-43rd week of pregnancy. The concentration of creatinine (172 cases), the ratio of lecithin/sphingomyelin (L/S-ratio, 155 cases) and phospholipid phosphorus (155 cases) were determined and related ...
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