Search Results
Results 451 - 500 of 828
< 5 6 7 8 9 10 11 12 13 14 15 >
Hooper S B - - 1995
1. During fetal life the lung develops as a liquid-filled organ. This liquid is produced by the fetal lung and leaves via the trachea from where it is either swallowed or enters the amniotic sac. Fetal lung liquid plays a crucial role in the growth and development of the lungs ...
Van Winter J T JT Department of Obstetrics and Gynecology, Mayo Clinic Rochester, MN - - 1995
Lung cancer during pregnancy is rare. Herein we describe a case of metastatic cancer of the lung in a 36-year-old pregnant patient whose initial complaint was pain in the left thigh. Management of this neoplasm during pregnancy depends on the gestational age of the fetus and the potential operability of ...
Hata T - - 1995
Growth of the fetal lung has been monitored by left lung area (LLA), right lung area (RLA), and total lung area (TLA) from 14 to 41 weeks menstrual age in 116 normal Japanese fetuses. Growth of the fetal heart and chest has also been monitored by heart area (HA) and ...
Chen C M - - 1995
We have asked whether the function of a bovine source surfactant frequently used clinically (Survanta) could be enhanced after exposure to the very preterm lung when the surfactant was subsequently tested in vivo in preterm surfactant-deficient rabbits. We also evaluated whether there would be effects resulting from fetal treatment with ...
van den Steen P - - 1995
In studying epithelio-stromal interactions in the neonatal hamster lung, basal centrioles, basal cilia and open-ring centrioles attracted our attention. The same structures are also found in bronchiolar epithelium of a 3-week-old fawn-hooded rat, indicating that they are not specific phenomena of hamster lung. Although cells with basal centrioles are not ...
Dudkiewicz J - - 1995
The aim of the study was to investigate the effect of L-thyroxine on prenatal lung maturation. Forty pregnant women with indications to preterm delivery were divided into two subgroups: A--30 patients suffering from insulin dependent diabetes mellitus, B--10 patients with other pathology of pregnancy. 500 micrograms L-thyroxine "Henning" was injected ...
Bourbon J R - - 1995
Pulmonary surfactant is a lipoprotein complex produced by type II pneumocytes that lines and stabilizes alveoli. Surfactant-specific proteins are early markers of the embryonic lung. Precursors of type II pneumocytes appear to be committed early and are able to pursue their differentiation program in a relatively autonomous way. Despite this ...
Harding R - - 1995
This paper reviews recent evidence from epidemiological, follow-up and experimental studies that sub-optimal conditions during gestation can cause alterations in respiratory function that persist during postnatal life. Several studies indicate that placental insufficiency, which can be associated with fetal substrate deprivation, hypoxia and low birthweight, may be followed by evidence ...
Dong J T - - 1995
The effects of sodium arsenite (As) and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on epithelia of human fetal trachea and bronchiolar epithelia of human fetal lung were studied by using organ-cultured explants. In epithelium of human fetal trachea, 34 microM MNNG induced hyperplasia, metaplasia, and dysplasia; 1 microM As induced hyperplasia; and 3-9 microM ...
Nakakuki S - - 1994
According to the fundamental structure of the bronchial ramification of the mammalian lung proposed by the present author [5, 6], the lung of the striped dolphin (Stenella coeruleo-albus) consists of the cranial and caudal lobes on either side. Both lobes are united to form a single one. The middle and ...
Ford W D - - 1994
Despite improvements in surgical techniques, the results of open fetal surgery to correct congenital diaphragmatic hernia have been disappointing. Hysterotomy induces preterm labour and, where there is a large volume of liver in the fetal chest, reduction of the liver into the abdomen induces immediate fetal death. Less invasive techniques, ...
Scott R J - - 1994
Chorioamnionitis is a frequent finding in the placenta in second-trimester premature labor. Seventy-six archival perinatal and fetal autopsies between 15 and 28 weeks of gestation with a morphologic diagnosis of chorioamnionitis were reviewed. Of the 76 cases, 52 (68%) had inflammatory cells in the lungs, which is higher than the ...
deMello D E - - 1994
Thyroid hormones influence fetal and neonatal lung growth and maturation. However, the effect of naturally occurring, genetically determined hypo- or hyperthyroidism on fetal or neonatal lung maturation has not been examined. In the hyt/hyt mouse, primary hypothyroidism, which is characterized by a high serum TSH concentration, is transmitted as an ...
Chinayon P - - 1994
A successful pregnancy outcome in a patient with previous heart-lung transplantation is reported. A 22-year-old primigravid woman received heart-lung transplantation for Eisenmenger's ASD and conceived 22 months postoperatively. She had been continuously treated with cyclosporine, azathioprine and prednisone during pregnancy. Her antenatal course was uneventful. At 39 weeks' gestation, she ...
Das R M - - 1994
Trichloroethylene (TCE) has previously been shown, in adult mouse lung, to alter the distribution of phospholipid associated with the pulmonary surfactant and to affect the activity of phospholipase A2, an enzyme involved in synthesis of the surfactant. However there are no data available on the effects of maternal exposure to ...
Gibbs G W - - 1994
The membrane filter (MF) method for evaluating asbestos fibre concentrations was introduced in the 1960s. Before that time the midget impinger (MI) was used in North America, while the long running (LRTP) and regular thermal precipitator (TP) were used in the U.K. All studies from which estimates of long-term health ...
Pelosi MA - - 1994
This presentation describes the successful laparoscopic removal of an interstitial ectopic pregnancy. Interstitial pregnancy is rare (2%-4% of tubal pregnancies). Due to its location, rupture usually results in hemorrhagic shock. Current treatments include cornual resection, hysterectomy, local injection of potassium chloride or methotrexate, and systemic methotrexate. The laparoscopic treatment of ...
Matcher S J - - 1994
We describe a simple technique for non-invasively determining the absolute concentration of deoxyhaemoglobin (Hb) in living tissue using near infrared spectroscopy (NIRS). The technique uses second-differential spectroscopy to determine the relative concentration of Hb to tissue water by fitting of the spectral features of these two chromophores in the 710 ...
Murotsuki J - - 1994
A case of type III congenital cystic adenomatoid malformation of the lung was successfully diagnosed prenatally by fetal lung biopsy. We performed this procedure at 22 weeks of gestation, using a biopsy gun system under ultrasound guidance. The pregnancy was undisturbed by the procedure but as the condition was incompatible ...
Rotschild A - - 1994
Two major factors can interfere with normal development of the fetal lungs: mechanical constriction resulting in decreased intrathoracic space and reduced or absent fetal breathing movements. We report a unique case in which both factors contribute to the development of lethal pulmonary hypoplasia. This full-term neonate had an isolated unilateral ...
Baker P N - - 1994
OBJECTIVE: To measure fetal lung volume by echo-planar magnetic resonance imaging (MRI). METHODS: Twenty singleton pregnancies were scanned on one occasion each using echo-planar imaging, a form of MRI. Cases of fetal growth restriction and macrosomia were excluded from the study. RESULTS: Lung volumes increased with gestational age from 21 ...
Tabor B L - - 1994
The relationship between cortisol infusion and time of fetal catheterization on postnatal lung function of prematurely delivered lambs was investigated with the hypothesis that the intervention of catheterization would alter fetal responsiveness to the maturational effects of corticosteroids. Fetal catheterization was performed on d 117 or on d 122 of ...
Puranik B M - - 1994
The study deals with evaluation of pulmonary function status in fifty normal pregnant women tested monthly. The parameters studied were Vital Capacity (VC) Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1st second (FEV1) using Vitalograph Spirometer; tidal volume (VT), inspiratory capacity (IC) and expiratory reserve volume (ERV) using ...
Pairon J C - - 1994
Exposure to asbestos was evaluated in 131 patients with pleural malignant mesothelioma in the Paris area between 1986 and 1992 using data from a detailed specific questionnaire and light microscopy analysis of the retention of asbestos bodies in bronchoalveolar lavage fluid or lung tissue. Probable or definite exposure to significant ...
Etches P C - - 1994
Severe fetal hydrops associated with cystic adenomatoid malformation of the lung inexplicably resolved spontaneously at 33-34 weeks' gestation. Following postnatal resection of the lesion which was of the macrocystic variety, the infant's respiratory status deteriorated, requiring 1 week of complicated support with extracorporeal membrane oxygenation. The baby survived and was ...
Kyle P M - - 1994
Fetal pulmonary malformations comprise a rare but often lethal group of congenital anomalies. Until recently, diagnosis and therapy were directed postnatally and therefore some cases of fetal compromise were inevitably missed. We present 2 cases in which intermittent thoracentesis of fetal cystic lung malformations resulted in a successful outcome. Intrauterine ...
DiFiore J W - - 1994
Infants with congenital diaphragmatic hernia (DH) and profound pulmonary hypoplasia are currently unsalvageable. The authors previously demonstrated that tracheal ligation (TL) accelerates fetal lung growth and reverses the pulmonary hypoplasia of fetal nephrectomy. The purpose of this study was to determine if the pulmonary hypoplasia of experimental DH could be ...
Sutliff K S - - 1994
Esophageal atresia and tracheoesophageal fistula, common malformations of the respiratory and digestive tracts, are of unsettled pathogenesis. Part of the difficulty in understanding these abnormalities arises from the uncertainties about the normal developmental processes in the region. This study examined the development and fate of the tracheoesophageal septum. Normal human ...
Botha A S AS Department of Paediatrics and Child Health, University of Natal, - - 1994
Home nebulisers are extensively used in the ambulatory treatment of chronic chest conditions. This study compares the intrapulmonary deposition of aerosol generated by 6 different models of electrical home nebuliser in healthy male volunteers. Deposition was quantified by measurement of the radio-activity over the right lung during nebulisation of 3 ...
Das R M - - 1994
Mercury ingested from dietary sources has potent neurotoxic and teratogenic effects. Initial studies have shown that mercury may also affect fetal lung development. Since these pulmonary effects may play a role in subsequent neonatal morbidity and mortality due to compromising of the development of the lung, mercury effects in fetal ...
Shigeta H - - 1993
Epidermal growth factor (EGF) immunoreactivity, EGF binding activity, and their ontogenic changes were investigated in placenta, amnion, and various organs of mouse fetus and neonate. EGF immunoreactivity was detected in all organs examined such as fetal and neonatal liver, brain, lung, intestine, placenta, and amnion. The fetal tissues having relatively ...
Diekman M A - - 1993
From 2 to 4.5 months of age, 80 crossbred gilts were reared in a conventional grower unit where they were naturally exposed to mycoplasmal and bacterial pathogens that cause pneumonia and atrophic rhinitis. At 4.5 months of age, gilts were moved to environmentally regulated rooms (4.9 x 7.3 m) and ...
Miller A A - - 1993
Our aim was to determine the role of fetal breathing movements (FBM) in the maintenance of fetal lung liquid volume. Experiments were performed in 14 chronically catheterized fetal sheep. FBM were selectively abolished for 48 h by the infusion of tetrodotoxin (TTX) onto the phrenic nerves of five fetuses. Lung ...
van den Besselaar A M - - 1993
A multi-center study of the three W.H.O. international reference preparations (IRP) for thromboplastin has been performed. The main purpose of the study was the determination of the mean international sensitivity index (ISI) of a proposed replacement IRP for thromboplastin, rabbit, plain. Twenty laboratories in Europe, North America, and Australasia participated ...
Barker P M - - 1993
Throughout gestation, fetal lung is filled with liquid secreted by the pulmonary epithelium. Factors responsible for secretion and for induction of liquid absorption by postnatal lung are poorly understood. We studied effects of "fetal" (3% O2-8% CO2) and "postnatal" (21% O2-5% CO2) gas tensions and of low hormone concentrations [media ...
Cudd T A - - 1993
We hypothesized that fetal lung contains and releases immunoreactive (ir) adrenocorticotropin (ACTH). Fetal sheep lung (89-145 days gestation, n = 13) irACTH content was 4,100 +/- 672 (SE) pg/g lung wet wt compared with 5,425 +/- 1,403 (SE) pg/g in adults (n = 5) when measured by radioimmunoassay (RIA). irACTH ...
Arahuetes R M - - 1993
Previous studies have shown that the increase of the enzymatic antioxidant defense that takes place in the fetal rat lung at the end of gestation can be accelerated by the synthetic glucocorticoid dexamethasone and diminished by metyrapone, a blocker of glucocorticoid synthesis. Since it is known that the fetal adrenal ...
Kuroki M - - 1993
Two molecular species of nonspecific cross-reacting antigens, NCA-90 and NCA-50 with mol. wts. of 90,000 and 50,000, respectively, were effectively extracted with phosphatidylinositol-specific phospholipase C (PI-PLC) from human lung tissues, followed by extraction with perchloric acid, immunoaffinity chromatography with anti-NCA adsorbent, and gel filtration on a TSK G3000SW column. The ...
Harding R - - 1993
Fetal breathing movements (FBM) are considered necessary for normal growth and structural maturation of the fetal lung, but the underlying mechanisms are unclear. The small fluctuations in lung dimensions caused by FBM have been proposed as a stimulus to lung growth, but it is equally possible that FBM act by ...
Hu J - - 1993
Corticostatin-I (CSI) is the most potent of the corticostatic peptides isolated from rabbit lungs and neutrophils. CSI was localized in cells by immunohistochemistry using highly specific polyclonal antisera raised against the synthetic peptide. Western blot showed a single 4-kilodalton band, indicating that the antibody employed was specific for CSI in ...
Adzick N S - - 1993
We reviewed our experience with fetal therapy for congenital cystic adenomatoid malformation of the lung (CCAM) at the University of California, San Francisco Fetal Treatment Center. Fetuses with life-threatening CCAM were selected for prenatal treatment according to predetermined guidelines, including the gestational age of the fetus, the size of the ...
Raja M A - - 1993
The case history of a 27 year old male ex-intravenous drug user who presented with haemoptysis and indistinct lung shadowing is reviewed. During a 3 week period of investigation his lung shadowing increased dramatically and it became apparent that he had metastases from chorionic gonadotropin-producing testis cancer which had undergone ...
Maritz G S - - 1993
The aim of the present study was to establish whether ascorbic acid supplementation (1 mg/kg/body mass/day) during pregnancy and lactation will prevent the effect of maternal nicotine exposure (1 mg/kg/body weight/day) on neonatal lung carbohydrate, DNA and protein metabolism. The data show that the adult lung ascorbic acid content was ...
Verhulst J - - 1993
The human lung shows permanent retention of certain features (such as the absence of an infracardiac lobe, or the subdivision of the lobes in lobules) found in most mammal fetuses or youngsters. This phenomenon seems to be in line with the fetalization theory of Louis Bolk, who considered man as ...
O'Brodovich H - - 1993
Because immature, in contrast to mature, fetal lungs have ineffective Na transport, we wished to determine the ontogeny of Na(+)-K(+)-ATPase expression in fetal distal lung epithelium (FDLE). FDLE and fibroblasts (FLF) from 17- to 22-day gestational age fetal rats (term = 22 days) were grown in primary culture. Northern and ...
Peterson B T - - 1993
An accurate and reproducible measure of solute concentration of lung epithelial lining fluid (ELF) by bronchoalveolar lavage would be valuable in lung research and in patient care. Measurements of the albumin/total protein ratio in a previously proposed rewash lavage procedure showed that albumin enters the lavage fluid. Therefore, the rewash ...
Adzick N S - - 1993
Prenatal detection and serial sonographic study of fetuses with lung lesions now make it possible to define the natural history of these lesions, determine the pathophysiologic features that affect clinical outcome, and formulate management based on prognosis. The prenatal diagnostic hallmarks and natural history of congenital cystic adenomatoid malformation of ...
Yasui S - - 1993
To clarify the precise role of epidermal growth factor (EGF) on fetal lung development, rabbit anti-mouse EGF (anti-mEGF) antiserum was administered to pregnant mice from days 10 to 17 during late gestation. Control mice were administered either normal rabbit serum (NRS) or physiological saline (PS). Serum EGF was not detected ...
Warren S E - - 1993
A 32-year-old woman, 12 weeks pregnant, presented with bilateral spontaneous pneumothorax that did not heal with tube thoracostomy. At right and left thoracotomy, lymphangiomyomatosis of the lung was found and treated by pleurodesis. Lymphangiomyomatosis has been infrequently reported in the surgical literature, even though it may befall the thoracic surgeon ...
Wu F F - - 1993
In order to elucidate the effects of corticosteroids on fetal hearts during midtrimester, pregnant rats were injected with a daily dose of betamethasone (1 mg/kg) from the 12th day through the 17th day of pregnancy. The fetal cardiovascular and pulmonary systems were studied on the 21st day of pregnancy (term). ...
< 5 6 7 8 9 10 11 12 13 14 15 >