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Gaillard R R 1] The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands [2] Department of Pediatrics, Erasmus Medical Center, Rotterdam, The Netherlands [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, The - - 2014
BackgroundExcessive gestational weight gain seems to be associated with offspring cardio-metabolic risk factors. Little is known about critical periods of gestational weight gain. We examined the associations of maternal weight gain in different periods of pregnancy with childhood cardio-metabolic risk factors.MethodsIn a population-based prospective cohort study from early-pregnancy onwards among ...
Genc Mine M Department of Obstetrics and Gynecology, Şifa University School of Medicine, Fevzipaşa Bulvarı No:172/2, 35240, Basmane/Izmir, Turkey, - - 2014
The aim of the present study is to determine the potential risk factors for adenomyosis and to investigate its relationship with accompanying gynecological pathologies and clinical characteristics. This study is a retrospective analysis of 945 patients who underwent hysterectomy between May 2005 and January 2013 at the Sifa University Medical ...
Kovacs Christopher S CS Faculty of Medicine - Endocrinology, Memorial University of Newfoundland, St. John's, Newfoundland, - - 2014
To describe our current state of knowledge about the pathophysiology, incidence, and treatment of osteoporosis that presents during pregnancy, puerperium, and lactation. When vertebral fractures occur in pregnant or lactating women, it is usually unknown whether the skeleton was normal before pregnancy. Maternal adaptations increase bone resorption modestly during pregnancy ...
Welten M M The Generation R Study Group, Erasmus Medical Center, Rotterdam, The - - 2014
To assess whether variations in maternal haemoglobin levels during pregnancy are associated with cardio-metabolic risk factors in school age children. Population-based prospective cohort study. Rotterdam, The Netherlands, 2002-2012. Mothers and children (n = 5002) participating in the Generation R Study. We obtained maternal haemoglobin levels during early pregnancy (median gestational age 14.6 weeks ...
Chiou Wen-Ko WK Department of Industrial Design, Chang Gung University, Kweishan, Taoyuan, Taiwan, - - 2014
In this study, a time-series approach was used to measure women's feet to accurately analyze changes in foot size and body mass during pregnancy. One-hundred women who were pregnant for the first time were asked to respond to questions on subjective complaints of foot discomfort listed in a questionnaire. Among ...
Rosenfeld Charles R CR University of Texas Southwestern Medical School - - 2014
Mechanisms regulating uteroplacental blood flow (UPBF) in pregnancy remain unclear, but likely involve several integrated signaling systems. Endothelium-derived nitric oxide (NO) is considered an important contributor, but the extent of involvement is unclear. Bolus intra-arterial infusions of L-nitro-arginine methyl ester (L-NAME) modestly decrease ovine basal UPBF; however, the doses and ...
Kumar Pradeep - - 2014
Ruminant placentas synthesize pregnancy-associated glycoproteins (PAGs) during pregnancy, which serve as biomarkers of pregnancy. The present study was conducted to verify, whether PAGs are expressed in buffalo placenta by using lectin-based affinity chromatography and peptide mass finger printing (PMF). Fetal cotyledonary tissues were collected from gravid uteri procured from slaughtered ...
Rosso Mićo - - 2014
The case report describes a 29-year-old nulliparous woman that was admitted at the Department of Gynecology and Obstetrics of the Clinical Hospital Osijek complaining of mild abdominal pain without vaginal discharge. The patient's menstrual cycle was irregular, from 30-45 days. An ultrasound examination showed suspicion of an ectopic pregnancy with ...
Tayyar Ahmet A Harris Birthright Research Centre of Fetal Medicine, King's College Hospital, London, - - 2014
Objective: To assess risk for preeclampsia (PE) based on maternal characteristics, mean arterial pressure (MAP) and uterine artery pulsatility index (Ut-PI) at 30-33 weeks' gestation. Methods: Screening study in singleton pregnancies including 2,140 that subsequently developed PE and 83,615 that were unaffected by PE, gestational hypertension or delivery of small-for-gestational-age ...
Gallo Dahiana D Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, - - 2014
Objectives: To assess the performance of screening for preeclampsia (PE) by mean arterial pressure (MAP) at 11-13 and at 20-24 weeks' gestation. Methods: MAP was measured at 11-13 and 20-24 weeks in 17,383 singleton pregnancies, including 70 with early PE, requiring delivery <34 weeks' gestation, 143 with preterm PE, delivering ...
Lelic Melisa - - 2014
Sideropenic anemia is a common pregnancy disorder. Depending on severity, maternal anemia can significantly influence morphometric characteristic of placental tissue, pregnancy course and outcome. to estimate if maternal anemia a) results with significant placental changes; b) influence on newborn weight, length and vitality. Research included 100 women and their newborns, ...
Khalil Asma - - 2013
The aim of this study was to investigate the longitudinal changes in uterine artery mean pulsatility index (Ut-PI) and mean arterial pressure (MAP) in women who subsequently develop preeclampsia (PE) and gestational hypertension (GH). This was a prospective longitudinal study in singleton pregnancies identified by screening at 11(+0) -13(+6)  weeks' ...
Díaz-Guerrero L - - 2013
Objective: The aims of this study were to determine (a) whether the normal pericallosal vascular map can be visualized using color Doppler ultrasonography in normal fetuses in the first trimester of pregnancy and (b) whether an abnormal pericallosal artery (PA) vascular map can be observed in fetuses with corpus callosum ...
Bauer Ashley J AJ Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, - - 2013
Preeclampsia is a pregnancy-specific condition characterized by an imbalance of circulating angiogenic factors and new-onset hypertension. Although current treatment options are limited, recent studies suggest that pravastatin may improve angiogenic profile and reduce blood pressure in preeclampsia. We hypothesized pravastatin would restore angiogenic balance and reduce mean arterial pressure (MAP) ...
Lupton Samantha J - - 2013
The microvasculature plays an important role in regulating cardiovascular changes in pregnancy, but changes in microvasculature have been difficult to document in vivo. This study objectively quantifies changes in the maternal retinal arteriolar and venular caliber over the course of healthy pregnancy. Healthy pregnant women (n=53) were recruited from Royal ...
Kuc Sylwia - - 2013
In a previous study, we have described the predictive value of first-trimester Pregnancy-Associated Plasma Protein-A (PAPP-A), free β-subunit of human Chorionic Gonadotropin (fβ-hCG), Placental Growth Factor (PlGF) and A Disintegrin And Metalloprotease 12 (ADAM12) for early onset preeclampsia (EO-PE; delivery <34 weeks). The objective of the current study was to ...
Prajapati Saloni R SR Department of Obstetrics and Gynaecology, SSG Hospital, Government Medical College, Aanandpura, Baroda, 390001 India ; Satyanarayan Bunglows, Opp. Vardhman Complex, Subhanpura, Baroda, 390023 - - 2013
To determine the clinical value of uterine artery Doppler Pulsatility index (PI) at 22-24 + 6 weeks scan and importance of maternal history and mean arterial pressure (MAP) in the prediction of pre-eclampsia. This was a prospective screening study of 200 women with singleton pregnancy. Maternal history and blood pressure were recorded, and ...
Lateef Aisha - - 2012
Systemic lupus erythematosus (SLE) is an autoantibody-mediated systemic autoimmune disease, predominantly affecting young females. Pregnancy is increasingly common in the setting of SLE, as survival and quality of life of patients improve. Although live births can be achieved in the most cases, pregnancy in patients with SLE remains a high-risk ...
Baruselli Ps - - 2012
Over the last several decades, a number of therapies have been developed that manipulate ovarian follicle growth to improve oocyte quality and conception rates in cattle. Various strategies have been proposed to improve the responses to reproductive biotechnologies following timed artificial insemination (TAI), superovulation (SOV) or ovum pickup (OPU) programmes. ...
Enzensberger Christian - - 2012
Premature constriction or closure of the ductus arteriosus can occur during fetal life. It is a rare phenomenon and has been described secondary to medication or structural lesions or as idiopathic constriction. Premature closure of the ductus arteriosus can lead to progressive right heart dysfunction with tricuspid regurgitation, congestive heart ...
Berger-Kulemann V - - 2012
BACKGROUND AND PURPOSE:The quality of spectroscopic studies may be limited because of unrestricted fetal movement. Sedation is recommended to avoid motion artefacts. However, sedation involves side effects. The aim of this study was to assess the feasibility and quality of brain (1)H-MR spectroscopy in unsedated fetuses and to evaluate whether ...
Salihagić Kadić Aida - - 2012
More than 99% of the human neocortex is fashioned during intrauterine life, resulting in the fascinating diversity of fetal functions and activities. The objective of this review is to present the most significant neurodevelopmental events, as well as new findings about prenatal motor and sensory development.
Vo Thin - - 2012
Adverse events in utero can be critical in determining quality of life and overall health. It is estimated that up to 50 % of metabolic syndrome diseases can be linked to an adverse fetal environment. However, the mechanisms linking impaired fetal development to these adult diseases remain elusive. This review uncovers ...
Bencaiova Gabriela - - 2012
To assess the prevalence of decreased iron stores and anemia in pregnant women. To determine whether the risk factors: socio-demographic background, age, BMI, and parity are associated with abnormal hemoglobin concentrations and/or abnormal iron status. A longitudinal study was carried out at the Department of Obstetrics, University Hospital of Zurich ...
Hussain Rubina - - 2012
Unintended pregnancy and unsafe abortion are common in Kenya, leading to high levels unplanned births and avoidable maternal injury and death. Until recently, abortion was only legally permissible to save the life of a woman, but a new constitution adopted in 2010 includes language that makes abortion available to protect ...
Robinson Barrett K - - 2012
OBJECTIVE: The purpose of this study was to compare strategies for delivery timing of uncomplicated monochorionic diamniotic twin pregnancies. STUDY DESIGN: A decision tree compared 9 strategies that included scheduled delivery between 32 and 38 weeks' gestation, with or without confirmation of fetal lung maturity. Outcomes in the model included ...
Steins Bisschop Charlotte N - - 2012
This systematic review aims to determine if there are evidence-based recommendations for the optimal mode of delivery for non-cephalic presenting first- and/or second twins. We investigated the impact of the mode of delivery on neonatal outcome for twin deliveries with (1) the first twin (twin A) in non-cephalic presentation, (2) ...
Johnstone-Ayliffe Carina - - 2012
Objective. To review the procedure-related complication rates following fetal blood sampling and intrauterine red cell transfusion for anaemic fetuses at a single tertiary center. Design. A retrospective study of 114 intrauterine transfusions. Setting. A single tertiary referral fetal medicine center at Queen Charlotte's and Chelsea Hospital, Imperial College London, London, ...
Aldabe Daniela - - 2012
The present systematic review assessed the level of evidence for the association between relaxin levels and pregnancy-related pelvic girdle pain (PPGP) during pregnancy. PRISMA guidelines were followed to conduct this systematic review. Electronic search was carried out using six different databases. Observational cohorts, cross-sectional or case-control studies focused on the ...
Foote A K - - 2012
Significant progress has been made in understanding and monitoring the causes of equine abortion over past decades. However, not all in utero pathology results in abortion. It has long been recognised that some in utero pathology, such as twinning or chronic placentitis, can result in the birth of live but ...
Foote A K - - 2012
Significant progress has been made in understanding and monitoring the causes of equine abortion over past decades. However, not all in utero pathology results in abortion. It has long been recognised that some in utero pathology, such as twinning or chronic placentitis, can result in the birth of live but ...
Benson Michael D - - 2012
Background/Aims: To test the hypothesis that obstetrical disseminated intravascular coagulopathy results from an excessive leakage of fetal material into the maternal circulation. Methods: All peripartum hysterectomy cases for hemorrhage at two suburban Illinois hospitals over 10 years were included. Intravascular presence of fetal material was determined by two pathologists blinded ...
Falcón B J - - 2012
Spontaneous pregnancy loss is often associated with aberrant maternal inflammation and systemic coagulopathies. However, the role of inflammation in the development of obstetric coagulopathies is poorly understood. Further, questions remain as to whether systemic coagulopathies are linked to placental haemostatic alterations, and whether these local alterations contribute to a negative ...
Demir B - - 2012
To assess the effect of isolated teratozoospermia with a normal sperm count and total motility by means of the fertilization rates, embryo quality and clinical pregnancy rate only in ICSI cycles. We retrospectively analyzed the records of patients who underwent ICSI at Hacettepe University, Faculty of Medicine, Department of Obstetrics ...
Greuter Marjolein J E - - 2012
Diabetes during pregnancy can lead to severe risks for both mother and fetus when it is not managed properly. The use of rigorously developed guidelines with a robust implementation process can have a positive influence on the management of diabetes during pregnancy. This study aims to compare recommendations and assess ...
Sueldo Carolina M - - 2011
Untreated hydrosalpinx is known to decrease in vitro fertilization success. We report on 4 patients with hydrosalpinx for whom fresh transfers of 11 good quality embryos did not produce a pregnancy; however, frozen blastocyst transfers in natural cycles resulted in several successful pregnancies, with an implantation rate of 60% (9/15 ...
Wu Linda L-Y - - 2011
Obesity can have detrimental effects on pregnancy rates in natural conceptions and also in women undergoing IVF or intracytoplasmic sperm injection (ICSI). This review summarises the most recent clinical literature investigating whether obesity impacts oocyte quality and early embryo growth. In other tissues, obesity leads to lipotoxicity responses including endoplasmic ...
Mourelo Mónica - - 2011
The maternal and perinatal fetal prognosis of preeclampsia depends on the gestational age of the fetus at onset, the severity of the disease, the quality of care, and the presence of pre-existent medical conditions. One of the uncommon effects of severe preeclampsia on the eye is sudden loss of vision. ...
Sidorov Evgeny V - - 2011
Ischemic infarcts and hemorrhages are uncommon but dangerous complications of pregnancy. Their etiology is related to physiological changes during pregnancy. The majority of strokes are seen in the third trimester and postpartum and are etiologically related to three conditions: reversible cerebral vasoconstriction syndrome, preeclampsia/eclampsia and cerebral venous thrombosis. The first ...
Juan-Sallés Carles - - 2011
Localized, myocardial toxoplasmosis contributed to the death of a female ring-tailed lemur (Lemur catta) 1 week after the delivery of 4 stillborn offspring with disseminated toxoplasmosis; the diagnosis was obtained by histopathology and immunohistochemistry in all 5 lemurs. Varying degrees of placentitis and placental edema with intralesional Toxoplasma gondii immunolabeling ...
Chen H - - 2011
AIM: The aim of this study is to assess the changes in coagulation, thrombosis, anticoagulation, and fibrinolysis during early pregnancy. METHODS: One hundred and five pregnant women with monozygotic pregnancies between 10 and 12 weeks gestation were randomly enrolled as the study group, and another 82 non-pregnant women were selected as ...
Laflamme Elise M - - 2011
Iron-deficiency anemia is often under-diagnosed in developing countries, specifically in pregnant populations in regions of high altitude. Hemoglobin levels are not consistently adjusted for elevation, and therefore many anemic patients are left undiagnosed. The purpose of this study was to incorporate current parameters for diagnosing anemia in pregnancy at high ...
Koo Hwa Seon - - 2011
Peritoneal pregnancy is an implantation in the peritoneal cavity exclusive of tubal, ovarian, or intra-ligamentary implantations. This is a rare obstetric complication with high maternal mortality and even higher perinatal mortality, and secondary type was most common. Risk factors for peritoneal pregnancy are previous history of extrauterine pregnancy or tubal ...
Tate Jessica J Wake Forest University Baptist Medical Center Stroke Center, Women's Health Center of Excellence, Wake Forest University Health Sciences, Winston Salem, NC 27157, - - 2011
Stroke, the sudden onset of brain dysfunction from a vascular cause, is one of the most common causes of long-term disability. Although rare during childbearing years, stroke is even more devastating when it occurs in a young woman trying to start a family. Pregnancy and the postpartum period are associated ...
Matsubara Shigeki - - 2011
Headache in late pregnancy is warning of the presence of severe and/or lethal disorders. Here, we present a case of Vogt-Koyanagi-Harada disease (VKH), in which headache was the preceding and predominant symptom. At 37 weeks of pregnancy, a Japanese 1-para woman with an uneventful pregnancy complained of severe headache and then ...
Sammaritano Lisa R - - 2010
Pregnancy, whether normal or complicated, induces change in nearly every system of the body. Because most rheumatologic disorders are multisystemic and often affect young women, it may be difficult to differentiate pregnancy-related change from new onset or exacerbation of rheumatic disease. Familiarity with common manifestations of pregnancy is important in ...
Almeida Carlos - - 2010
Myasthenia gravis is an autoimmune neuromuscular disease, usually affecting women in the second and third decades. The course is unpredictable during pregnancy and puerperium. Myasthenia gravis can cause major interference in labour and partum and exacerbations of the disease frequently occur. The aim of this series of cases is to ...
Han Y W - - 2011
Studies on the link between periodontal disease and adverse pregnancy outcome have gone through several phases. The epidemiological studies predominantly support a positive association between these wide-affecting diseases. During the intervention phase, a few small-scale, single-center studies reported improvement of birth outcome following periodontal treatment, whereas the large-scale multi-center studies ...
Boronat Mauro - - 2011
Background. Ketoconazole is the most widely used medical treatment for Cushing's syndrome, but, because of its potential to cause birth defects, it is not recommended during pregnancy. Specifically, due to its antiandrogenic effects, ketoconazole entails theoretical risks of interfering with the development of external genitalia in male fetuses. Case. A pregnancy was ...
Tanous David - - 2010
OBJECTIVES: The objectives of this study were to examine: 1) B-type natriuretic peptide (BNP) response to pregnancy in women with heart disease; and 2) the relationship between BNP levels and adverse maternal cardiac events during pregnancy. BACKGROUND: Pregnancy imposes a hemodynamic stress on the heart. BNP might be a useful ...
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