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Alcalay M - - 1992
Adult polycystic kidney disease is an inherited disease that is transmitted as an autosomal dominant trait. The clinical manifestations, which develop during the third or fourth decade of life, usually do not affect women during childbearing age and thus do not affect fertility or pregnancy outcome. The patient presented here ...
Verwilghen J - - 1992
A 30-year-old woman with a 12-year history of palindromic rheumatism without progression to chronic arthritis experienced pronounced reduction of arthritic symptoms during both of her 2 pregnancies with, on each occasion, symptoms recurring 3 months after delivery. This is the first reported case suggesting an ameliorating effect of pregnancy on ...
Barth R A - - 1992
Autosomal recessive polycystic kidney disease is frequently diagnosed in utero by obstetric ultrasonography. We report a case in which there were varying outcomes of this disorder in three affected fetuses in a family. Recognition of variable expression within one family is important when parents are considering termination of a pregnancy ...
Happle R - - 1992
BACKGROUND: Restrictive dermopathy is an autosomal recessive phenotype characterized by universal tautness of skin resulting in fetal akinesia and death during the neonatal period. The clinical signs and symptoms of this uncommon disease are described in two brothers, and evidence is provided that fetal biopsy specimens obtained during the 20th ...
Morton M R - - 1992
A case of inflammatory bowel disease (IBD) presenting in pregnancy is described. Despite previous reports of severe fulminating disease in this type of patient, this woman did well with an uncomplicated course; she responded to standard medical therapy and there were no fetal complications. IBD should not be a contraindication ...
Nelson J L - - 1992
Pregnancy outcome before disease onset was evaluated for women with rheumatoid arthritis (RA) and control women as part of a prospective case-control study of newly diagnosed RA. An analysis of women who were ever gravid revealed no statistically significant difference in any adverse pregnancy outcome between RA cases (n = ...
Kirkland C J - - 1992
Many women with congenital heart disease can successfully tolerate the profound hemodynamic changes associated with pregnancy and birth with a collaborative team approach to management of their disease. This article provides a discussion of the interaction between pregnancy and congenital heart disease (including left-to-right shunts, obstructive lesions, and cyanotic defects), ...
Chuah S Y - - 1992
Patients with cyanotic congenital heart disease who have obstruction proximal to the pulmonary arteries and, hence, do not develop pulmonary hypertension, can go through pregnancy successfully, if the pregnancy and delivery are adequately cared for, with possible complications in mind. We report a successful pregnancy in a woman with congenital ...
Robinson T W - - 1992
Pregnancy in a renal homograft recipient resulted in an emergency cesarean section at 32 weeks' gestation secondary to maternal small bowel obstruction with necrotic bowel and subsequent intestinal perforation. The 1814 gm female product of this pregnancy had a moderate degree of in utero asphyxia, which subsequently, based on radiologic ...
Aso T - - 1992
Takayasu arteritis is a non-specific chronic inflammatory vascular disease of unknown etiology. Since the incidence of this disease in the child-bearing years is relatively high, the management of pregnancies with this disease is of great importance in clinical obstetrics. This study is aimed at discussing the maternal management and obstetrical ...
Pozaic S - - 1992
Previously considered a pediatric disorder, cystic fibrosis (CF) is becoming a more common complication of pregnancy as these patients have increasing life expectancies. CF produces profound physiologic alterations in major organ systems. These alterations augment the physiologic changes of pregnancy. Perinatal nurses can meet the complex needs of these patients ...
Hopkinson N D - - 1992
AIMS: To determine the effect of pregnancy on C4d concentrations and to assess whether C4d remains a useful disease activity marker in the management of connective tissue diseases during pregnancy. METHODS: Plasma C3, C4, and C4d concentrations were measured in 83 women at various stages of normal pregnancy and compared ...
Ozoh J O - - 1992
We present the third case of hepatoma in pregnancy to be reported in an African. Despite the high incidence of hepatoma in the male population, hepatoma complicating pregnancy is very rare in this environment. Death usually occurs within one year of onset of symptoms. The clinical features during pregnancy do ...
Matsumura A - - 1992
To evaluate the influence of pregnancy on the morbid condition of Takayasu arteritis, we summarized the clinical data and pregnant courses of 18 patients with Takayasu arteritis and a total of 22 deliveries. We followed C-reactive protein (CRP) scores in 16 of 18 patients (20 of 22 deliveries) to ascertain ...
Lew S Q - - 1992
Peritoneal dialysis is the preferred form of dialysis during pregnancy because it is continuous and lacks the wide variation in chemistries, weight and blood pressure, and avoids the use of anticoagulation necessary during hemodialysis. This is a case report of a successful vaginal delivery of a 35 week healthy baby ...
Bernardi S - - 1991
The influence of pregnancy on the relapse rate (number of relapses per person per year) in MS was analysed for 52 women who had a pregnancy during the disease. The relapse rate was lower during the pregnancy-year (9 months of pregnancy and 6 months immediately post partum) than the non-pregnancy ...
Doherty M - - 1991
Inorganic pyrophosphate (PPi) levels were estimated by radiometric assay in urine and in synovial fluid (SF) from asymptomatic, nonarthritic knees of patients with untreated metabolic disease and normal controls. SF PPi was significantly elevated in patients with hyperparathyroidism (mean +/- SEM 19 +/- 3 microM; n = 9), hemochromatosis (23 ...
Nagura Y - - 1991
Various effects on renal function and factors which tend to cause aggravation in pregnancy and delivery in patients with renal diseases have been described previously. In the present study, the authors undertook personal and telephone inquiries to patients with renal insufficiency due to aggravated renal dysfunction occurring during the course ...
Greer I A - - 1991
OBJECTIVE: To review the obstetric and gynaecological problems in women with congenital coagulopathies. DESIGN: Retrospective review. SETTING: Regional Adult Haemophilia Unit, Glasgow Royal Infirmary. SUBJECTS: All women in contact with the Unit over a period of 30 years, comprising eight with von Willebrand's disease, 18 obligate carriers of haemophilia A ...
Ostensen M - - 1991
The present investigation was undertaken to study the relationship between pregnancy and juvenile rheumatoid arthritis (JRA), with regard to possible reactivation of the disease, complications at delivery, and postpartum complications. Data on 76 pregnancies in 51 JRA patients were collected retrospectively. Comparison of pre-pregnancy disease activity with the course during ...
Soong Y K - - 1991
Infertility and amenorrhea are reported in most cases of Wilson's disease. In this report, we describe a case of Wilson's disease with pancytopenia and liver cirrhosis for over 4 years, without any specific treatment. After 2 years of D-penicillamine therapy, the patient became pregnant and delivered a liver mature female ...
Saade G - - 1991
Bernard-Soulier Syndrome is a rare autosomal recessive bleeding disorder characterized by a normal or low platelets count, the presence of giant platelets, and a prolonged bleeding time. Only five pregnant patients with this disease have been previously reported. Most of the complications seem to occur in the intrapartum or postpartum ...
Bloom A L AL Department of Haematology, University Hospital of Wales, Cardiff, United - - 1991
The physiologic mechanisms that influence plasma levels of von Willebrand factor (vWF) are poorly understood but include race, blood group, age, pregnancy, exercise, and adrenergic and neurohumoral stimuli. Inherited abnormalities in von Willebrand's disease (vWD) are associated with a defect of the vWF gene on chromosome 12, but in some ...
Vrins A - - 1991
A retrospective of 69 bronchoalveolar lavages (BAL) on horses was done to investigate the relationship between bronchoalveolar cell types and clinical signs in horses with small airway disease. Horses were grouped according to clinical findings. The groups were as follows: I. cough only (n = 14), II. cough with mucopurulent ...
McLigeyo S O - - 1991
In a 6 year period (1984-1989) we have had the opportunity to take care of five patients who had nephrotic syndrome and became pregnant. Four of them had mesangial proliferative glomerulonephritis while one had focal segmental glomerulosclerosis. Four of the pregnancies went to term while one was terminated at 34 ...
Schorr-Lesnick B - - 1991
Severe liver diseases occur in less than 0.1% of pregnancies. Accurate diagnosis and appropriate therapy are essential to the health and survival of both the mother and fetus. Because of their low incidence and the fact that most pregnant women are cared for primarily by their obstetricians, gastroenterologists only infrequently ...
Lee W - - 1991
Peripartum cardiomyopathy is an important cause for idiopathic heart failure associated with pregnancy. Current evidence suggests a potential role for myocarditis in the pathogenesis of this disease. About 3% to 4% of these patients present before delivery. Another group of patients with prior history of this disease request information about ...
Everson G T - - 1991
The gallbladder should be viewed as a hormonally responsive organ whose normal physiology may be altered by conditions ranging from intestinal disease to pregnancy. Disorders or conditions characterized by altered gallbladder motility predispose persons to gallstone formation. Recent studies of gallbladder sludge and the gallbladder motility of gallstone patients suggest ...
Jungers P - - 1991
Whether or not pregnancy adversely affects the natural course of underlying primary renal disease, and whether fetal outcome is influenced by the type of renal disease per se are controversial issues. We retrospectively analyzed the fetal and maternal outcome in 148 women with various, biopsy-proven histological types of primary chronic ...
Sibai B M - - 1991
Medical disorders, including hypertensive diseases, may exist prior to pregnancy (eg, connective tissue diseases, chronic hypertension, thyroid disease) or may manifest themselves for the first time during pregnancy (eg, gestational diabetes, gestational hypertension). The outcome for a particular pregnancy will depend on the nature of the disease, the severity of ...
Ishii N - - 1991
Dermatomyositis is a rare disease complicating pregnancy. We treated a patient in whom two pregnancies were complicated by dermatomyositis. In the first of the two gestations, a mild form of the disease arose in the last trimester. In the second gestation, the disease was inactive following treatment with 0.3 mg/kg/day ...
Macnicol A M - - 1991
The availability of methods for early accurate identification of individuals at risk of developing adult polycystic kidney disease (ADPKD) has raised a number of important clinical problems. As part of a project on clinical and genetic aspects of ADPKD, we have assessed the knowledge and attitudes of patients and their ...
Angelico M - - 1990
Biliary sludge has been for many years a poorly defined entity, usually with low amplitude, nonshadowing echoes within the most dependent part of the gallbladder, which shift under the influence of postural changes. From a sonographic point of view, the detection of sludge implies the coexistence of small-sized, solid components ...
Wong D J - - 1990
The clinical course of malignant melanoma in pregnancy has been a subject of controversy, but current evidence indicates that it is similar to the clinical course in non-pregnant patients. Early detection and biopsy of localized disease is crucial because early treatment provides an excellent prognosis. Surgical excision is the primary ...
Sit K H - - 1990
On resolving the ascertainment biases of the observed data in the geometric continuum vaffected-1 x P(sibship), where 0 less than v----infinity, four published ascertainments of rheumatic fever show excellent conformation with Mendelian recessive segregation, even in multiplex sibships. In two surveys in which ascertainment bias is near or a little ...
Bellamy N - - 1990
A 25-year-old patient presented at 14 weeks of her 3rd pregnancy with chondritis affecting the cartilaginous portion of her right ear. The clinical syndrome of recurrent chondritis, scleritis, iritis and arthritis supported a diagnosis of relapsing polychondritis. Fetal and maternal outcomes were favorable despite steroid dependent active disease during the ...
Baird D D - - 1990
The reproductive histories of 177 women with Crohn's disease and 84 women with ulcerative colitis were compared with those of healthy control subjects. Inflammatory bowel disease was associated with reduced fertility as measured by number of pregnancies, but measures of childlessness, infertility, fecundability, and methods of birth control suggested that ...
Shimoni Y - - 1990
Familial Mediterranean Fever (FMF) is an inherited disease, closely following the pattern of autosomal recessive inheritance. Amyloidosis is the most severe complication of the disease. The prevalence of pregnancy loss in women with FMF is considered to be high. There is no information to support the possibility of increase risk ...
Woolfson K - - 1990
Seventy-eight pregnancies in 50 patients were reviewed to evaluate the effects of Crohn's disease on the outcome of pregnancy and the influence of the pregnancy on the course of Crohn's disease. Overall, 21 pregnancies (27 percent) had abnormal outcomes including spontaneous abortions (9), infants small for gestational age (6), premature ...
Yu C P - - 1990
Letterer-Siwe disease is a rare proliferative disorder of the Langerhans cells, usually encountered inpatients under the age of 3 years. We present an unusual case of intrauterine fetal death at the 28th gestational week associated with generalized papular skin eruptions and systemic histiocytic infiltrates characteristic of Letterer-Siwe disease. Histopathologic features ...
Patton D E - - 1990
Cyanotic heart disease has major implications for maternal and fetal well-being during pregnancy. This article reports six patients with cyanotic congenital heart disease recently managed at our institutions. Although the maternal condition deteriorated to some extent during each pregnancy, it was the fetal condition that ultimately dictated delivery in each ...
Cunningham F G - - 1990
During the 18-year period from 1971 through 1988, 37 women whose pregnancies were complicated by moderate or severe renal insufficiency were managed at Parkland Memorial Hospital. Common maternal complications included anemia, chronic hypertension, and preeclampsia. Perinatal complications included midpregnancy losses and low birth weight from preterm delivery, fetal growth retardation, ...
Alstead E M - - 1990
Although azathioprine has been reported to be safe during pregnancy in renal transplant recipients and patients with systemic lupus erythematosus, opinions vary whether it should be continued in pregnancy in inflammatory bowel disease. A retrospective analysis of the outcome of 16 pregnancies in 14 women receiving azathioprine for inflammatory bowel ...
Valster F A - - 1990
In this report, a patient with known von Willebrand's disease is presented with severe thrombocytopenia developing during pregnancy, which at first was believed to be caused by immune thrombocytopenic purpura. For several reasons this first diagnosis had to be rejected, but subtyping of von Willebrand's disease pointed out that the ...
Avilés A - - 1990
Chemotherapy and obstetric care of 16 pregnant patients with non-Hodgkin's lymphoma are reported in this paper. All patients received chemotherapy during the various trimesters of pregnancy, including 8 cases during the first trimester, and there was no evidence of congenital malformations in any offspring. Fifteen babies are alive, healthy, and ...
Dudley D J - - 1990
Patients with rheumatic diseases who become pregnant are justifiably categorized as having high-risk pregnancies. Utilizing a multidisciplinary approach, including perinatologists, rheumatologists and anaesthetists, successful pregnancies have become the rule rather than the exception. However, women with rheumatic disease are particularly prone to develop serious obstetric problems which often result in ...
Crow J P - - 1990
Although echinococcal disease of the liver is common in some parts of the world, it is rarely seen in the United States. Even from endemic areas, few reports deal with its treatment during pregnancy. A 25 year old 18 week pregnant Italian woman presented with pruritus and right upper quadrant ...
Katz W E - - 1990
A 35-year-old white woman had recurrent episodes of adult onset Still's disease after 2 successive pregnancies. The second episode was characterized by an erythematous, macular rash, arthritis, fevers and hepatic dysfunction which occurred 2 months postpartum. The recurrent illness after pregnancy suggests that adult onset Still's disease may be influenced ...
Sutton R - - 1990
A retrospective review of 227 consecutive breast cancer patients who were 35 years of age or younger and who had been given doxorubicin-containing adjuvant chemotherapy was conducted to determine the frequency of pregnancy and its effect on the clinical course of the disease. Also, the status of the newborn was ...
Helman N S - - 1990
Sickle cell disease combined with pregnancy provides a challenge for the caregivers. A thorough understanding of the normals of both pregnancy and sickle cell disease, along with continuing assessment and astute observational skills, will allow the attending nurses to provide appropriate care to the patient. A pregnancy, labor, and delivery ...
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