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Naguib Ahmad H - - 2010
OBJECTIVE: To determine the safety and efficacy of using misoprostol vaginally for second-trimester abortion in women with a single previous cesarean delivery. METHOD: This prospective observational study was carried out at a university hospital in Egypt with 50 pregnant women with 1 previous cesarean delivery; a gestation of at least ...
Varras M - - 2010
Termination of pregnancy in the second trimester with misoprostol is safe and effective, but there is very limited published experience of its use in women with one or more previous cesarean sections. Uterine rupture might occur when misoprostol and oxytocin are used for pregnancy termination at the second trimester in ...
Dodd Jodie M - - 2010
A woman may need to give birth prior to the spontaneous onset of labour in situations where the fetus has died in utero (also called a stillbirth), or for the termination of pregnancy where the fetus, if born alive would not survive or would have a permanent handicap. Misoprostol is ...
Meir Karen - - 2009
Antenatal presentation of carnitine palmitoyltransferase type II deficiency due to mutations in the CPT2 gene has been rarely reported. We report an Ashkenazi Jewish family with 3 terminated pregnancies for multicystic kidneys and/or hydrocephalus. Fetal autopsy after termination of the couple's 4th pregnancy (sib 2) showed renal parenchyma replaced by ...
Chambers Dennis G - - 2009
A six-year audit of clinical outcomes following the treatment of suction termination of pregnancy-retained products of conception symptoms with 200 microg of misoprostol orally or sublingually three times a day for six doses showed that it was 93% effective and it reduced the repeat dilation and curettage rate by 79.6% ...
Chambers Dennis G - - 2009
OBJECTIVE: To compare the outcomes of 4 different perioperative misoprostol regimens for surgical termination of first-trimester pregnancy. METHODS: Retrospective analysis of the records of 4000 women (4 cohorts of 1000 each) who underwent surgical termination of pregnancy. The 4 cohorts received: no misoprostol; 200 microg of oral misoprostol 30 minutes ...
Parkar A P - - 2009
BACKGROUND: Ultrasound screening has been part of antenatal care for several decades, and warrants high expertise to meet the criteria for a worthwhile screening program. In particular, the rate of false positives should be low. PURPOSE: To examine time trends of pregnancy terminations for fetal abnormality after 12 weeks' gestation, ...
de Costa Caroline M - - 2009
The case that established the lawfulness of terminating pregnancy to preserve women's health.
Valiente C - - 2009
Gonadotropin-releasing hormone (GnRH) antagonists are particularly useful when a rapid inhibitory effect on the gonadal axis is required. The aim of this study was to test the efficacy and clinical safety of a low and high dose of the third generation GnRH antagonist, acyline, on pregnancy termination in female dogs. ...
Habiba M - - 2009
OBJECTIVE: To compare the experience and attitude of obstetricians in Europe towards late termination of pregnancy and the factors affecting their responses. DESIGN: Cluster sampling cross-sectional survey. All neonatal intensive care unit (NICU)-associated maternity units were recruited (census sampling) in Luxembourg, the Netherlands and Sweden. In France, Germany, Italy, Spain ...
da Silva Dalben Gisele - - 2009
Elective termination of pregnancy is prohibited in many countries, even after prenatal diagnosis of oral clefts. Though some studies address registries on termination of pregnancy, many investigations include only livebirths. This may lead to underestimation of the overall occurrence of oral clefts, influencing their reported prevalence. This paper does not ...
Mahjabeen - - 2009
OBJECTIVE: To compare the efficacy and safety of oral versus vaginal administration of misoprostol for second trimester pregnancy termination. STUDY DESIGN: Interventional, quasi experimental study. PLACE AND DURATION OF STUDY: The Department of Obstetrics and Gynaecology Unit-II, Fatima Jinnah Medical College/Sir Ganga Ram Hospital, Lahore, from August, 2003 to October, ...
Karsidag A Yasemin Karageyim - - 2009
OBJECTIVE: To compare the efficacy of vaginal versus sublingual misoprostol for second-trimester pregnancy termination, and to evaluate the effect on the blood flow of the uterine and umbilical arteries. METHODS: Forty-nine patients were randomized to receive either 200 microg of vaginal misoprostol every 6 hours or 200 microg of misoprostol ...
Kushwah Beenu - - 2009
OBJECTIVE: To compare the efficacy of misoprostol administered sublingually or orally for uterine evacuation after early pregnancy failure. METHOD: Forty-eight hours after receiving 200 mg of mifepristone orally, 100 women were randomized to receive misoprostol sublingually or orally. RESULTS: The evacuation rates were 92% in the sublingual and 84% in ...
Dickinson Jan E - - 2009
OBJECTIVE: Evaluation of factors influencing the duration of second-trimester pregnancy interruption with vaginal misoprostol for fetal abnormality. METHODS: All medical terminations >or=13 weeks of gestation 1/1997 to 12/2007 were prospectively identified. Cases receiving vaginal misoprostol 400 microg 6-hourly were extracted from the database and outcomes reviewed. RESULTS: This consecutive case ...
Niinimäki Maarit - - 2009
OBJECTIVE: To compare the frequency and risk factors for repeat abortions after surgical compared with medical termination of pregnancy. METHODS: Frequency of and risk factors for repeat abortions after medical (performed with mifepristone alone, or with a combination of mifepristone and misoprostol or other prostaglandins) compared with surgical (dilation and ...
Mirmilstein Vadim - - 2009
In Australia, the most common method of mid-trimester termination of pregnancy (TOP) is by medical induction with the prostaglandin E 1 analog misoprostol. This study was undertaken to compare the pregnancy outcomes of women who had undergone a misoprostol mid-trimester TOP in their last pregnancy with those of a similar ...
Teng Chieh-Lin - - 2009
Hemophagocytic lymphohistiocytosis (HLH), presenting with fever, cytopenia, liver dysfunction, hepatosplenomegaly, hypertriglyceridemia, and hyperferritinemia, is associated with various etiologies, including infections, collagen vascular diseases, and malignancies. The present report describes a 28-year-old woman who developed HLH combined with autoimmune hemolytic anemia (AIHA) at 23 weeks of gestation. Without response to corticosteroid, ...
Saichua Chatawan - - 2009
OBJECTIVES: To compare complete abortion rate, duration of abortion, and side effects between 600 microg powdery sublingual misoprostol and 600 microg sublingual misoprostol tablet for management of embryonic death or anembryonic pregnancy. MATERIALS AND METHODS: Fifty-four pregnant women up to 13 weeks of gestation diagnosed with embryonic death or anembryonic ...
Van Mensel Kristin - - 2009
Objective. To compare effectiveness, side effects, and patients' perception of vaginal misoprostol versus intravenous sulprostone for ending pregnancy after fetal death between 14 and 42 weeks gestation. Method. Multicenter randomized controlled trial, using block randomization, central allocation, and prior power analysis. Outcome measures. Induction-delivery interval, gastrointestinal side effects, use of ...
Ayati Sedigheh - - 2008
OBJECTIVE: To evaluate the efficacy of medical abortion at first trimester of pregnancy with vaginal misoprostol. METHODS: This is a descriptive analytic study. It was performed on 100 women at first trimester of pregnancy referred to teaching hospitals related to the Medical Sciences of Mashhad University, Mashhad, Iran for termination ...
Behrashi M - - 2008
The purpose of this study was to compare the efficacy and side effects of two different misoprostol regimens for second-trimester pregnancy termination. Sixty women in second trimester of gestation with indications for pregnancy termination were randomly assigned in two equal groups to receive either vaginal or oral misoprostol. The dosing ...
Macones George A - - 2008
In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed: Marc I, Rainville P, Masse B, et al. Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial. ...
Abigail Wendy - - 2008
AIMS AND OBJECTIVES: This article reports a systematic review of trend studies (1995-2006) which answers five questions: What are the patterns of: 1 Age of women seeking termination of pregnancy; 2 First ever pregnancy ending in a termination; 3 Contraception usage at the time of conception; 4 Contraception chosen immediately ...
Jansen Nicoline E - - 2008
OBJECTIVE: To compare two methods for second trimester termination of pregnancy: mifepristone and misoprostol versus Dilapan and sulprostone. METHODS: This was a randomized study involving 16 patients with a singleton live fetus with congenital malformations or genetic disorders. Eight patients were treated with 200 mg mifepristone orally followed by 200 ...
Hill James B - - 2009
We compared labor induced by vaginal misoprostol versus a supracervical Foley catheter and oral misoprostol. Singleton pregnancies at > or = 24 weeks' gestation were randomized to either an initial 25-microg dose of intravaginal misoprostol, followed by 50-microg intravaginal doses at 3- to 6-hour intervals, or a supracervical Foley balloon ...
von Hertzen Helena - - 2009
BACKGROUND: To identify an effective misoprostol-only regimen for the termination of second trimester pregnancy, we compared sublingual and vaginal administration of multiple doses of misoprostol in a randomized, placebo-controlled equivalence trial. METHODS: Six hundred and eighty-one healthy pregnant women requesting medical abortion at 13-20 weeks' gestation were randomly assigned within ...
Mulayim Baris - - 2009
OBJECTIVE: To assess the efficacy of sublingual misoprostol after surgical management of early termination of pregnancy (ETP) regarding duration and amount of bleeding, presence of retained products of conception (RPOC), and endometrial thickness. DESIGN: Prospective, randomized clinical trial. SETTING: University hospital. PATIENT(S): One hundred five patients admitted for possible management ...
Gipson Jessica D - - 2008
We conducted a mixed-method study in rural southwestern Bangladesh, a country in which an estimated 730,000 elective pregnancy terminations occur each year, to explore women's and couples' motivations to terminate pregnancies. Quantitative data derived from a 1998 cross-sectional survey and a longitudinal demographic surveillance system (1998-2003) were combined with qualitative ...
Lo T K - - 2008
OBJECTIVE: To explore whether the outcomes of second-trimester pregnancy termination for fetal abnormalities are affected by fetal diagnoses. METHODS: This was a retrospective review of cases undergoing second-trimester pregnancy termination for the fetal diagnoses of hemoglobin Barts, trisomy 21, and trisomy 18 during the period from 1999 to 2006. The ...
Chervenak Frank A - - 2008
Referral of pregnant patients for termination of pregnancy by physicians morally opposed to the procedure is ethically controversial, with polarized positions taken by physician organizations. Based on the ethical principles of beneficence and respect for autonomy, we establish the distinction between direct and indirect referral. Direct referral is beneficence based ...
Lipp Allyson - - 2008
AIM: To review the literature on attitudes of health care professionals to termination of pregnancy and draw out underlying themes. BACKGROUND: The controversy surrounding therapeutic abortion is unremitting with public opinion often polemic and unyielding. Nurses and midwives are at the centre of this turmoil, and as more termination of ...
Sloan Eileen P - - 2008
OBJECTIVES: To determine what evidence exists to support the practice of viewing the deceased fetus by women terminating pregnancy for fetal anomalies. DATA SOURCES: Electronic databases searched (1966-2007) were Medline, PubMed, Cumulative Index to Nursing and Allied Health Literature, and Dissertation Abstracts Index. STUDY SELECTION: Literature was reviewed that either ...
Ponnusamy S - - 2008
OBJECTIVE: To develop an in vivo model to determine fetal-cell enrichment efficiency of novel noninvasive prenatal diagnosis methods. METHODS: Efficiency of our three-step enrichment protocol was determined in vitro before fetal nucleated red blood cells (FNRBCs) were enriched from first-trimester maternal blood samples collected from the same patients pre- and ...
Abigail Wendy - - 2008
OBJECTIVES: The purpose of this study was to assess emerging trends in five characteristics: age, first ever pregnancy, contraception at time of conception, contraception choices post-operatively and referral source of women presenting for a termination of pregnancy (1996-2006) from a southern service in Adelaide, South Australia. METHOD: A time-series study, ...
Lo T K - - 2008
OBJECTIVE: To explore the effect of gestational age on the outcome of second-trimester termination of pregnancies for foetal abnormalities. METHOD: A retrospective study was conducted on 280 pregnancies terminated for foetal abnormalities in the second trimester using vaginal misoprostol. The gestational age at termination was divided into three groups: 13-16 ...
Carroll Mary A - - 2008
To compare markers of maternal bone metabolism between women who received a single compared with multiple courses of antenatal corticosteroids. This is an analysis of serum samples from a previously reported randomized, placebo-controlled, multicenter trial. Women at risk for preterm delivery after an initial course of corticosteroids were randomly assigned ...
Kaguelidou Florentia - - 2008
AIMS: Outcome of foetuses diagnosed with tetralogy of Fallot (TOF) or pulmonary atresia with ventricular septal defect (PA-VSD) and the reliability of foetal echocardiography to predict post-natal surgical outcome. METHODS AND RESULTS: Outcome of 218 foetuses having been diagnosed with TOF (n = 153) or PA-VSD (n = 65) was ...
Aladdin Yasser - - 2008
First-time seizure and status epilepticus during pregnancy have been previously reported as the initial manifestation of intracranial cavernous hemangioma. We report a woman with no history of seizures who presented with refractory status epilepticus at 10 weeks gestation. Cranial MRI revealed a right frontal cavernous hemangioma. The seizures remained refractory ...
Boza Alejandro Velazco - - 2008
Outdated second trimester abortion methods are still being used in some countries, and very few studies have compared them to currently recommended methods. To this end, we studied the efficacy and safety of vaginal misoprostol used alone for abortions in 189 women at 13-20 weeks gestation, in 2004-2006. We also ...
Rennie Janet M - - 2008
We have reviewed the current UK guidance regarding withholding and withdrawing life-prolonging treatment in the infant and termination of pregnancy for fetal malformation. We provide summaries of the key cases. The framework provided by professional bodies and the law in this difficult area stresses the importance of good and frequent ...
Pongsatha Saipin - - 2008
AIM: To compare the effectiveness of vaginal misoprostol between dry tablet insertion and gel form for second trimester pregnancy termination. METHODS: A non-blinded block randomized controlled trial was conducted on 148 pregnant women with live fetuses in the second trimester undergoing pregnancy termination. They were randomly allocated to receive vaginal ...
Wang Xuan - - 2008
The uncontrolled formation of amyloid fibers is the hallmark of more than twenty human diseases. In contrast to disease-associated amyloids, which are the products of protein misfolding, E. coli assembles functional amyloid fibers called curli on its surface using an elegant biogenesis machine. Composed of a major subunit, CsgA, and ...
- - 2008
(1) Misoprostol, a synthetic prostaglandin E1 analogue, is used to treat gastric and duodenal ulcers, and, in combination with mifepristone, for medical abortion. (2) The French and American summaries of product characteristics, based on data submitted to the relevant regulatory agencies, mention no teratogenicity in animals. However, some studies showed ...
Meyers, P; ;
The implementation of the Choice on Termination of Pregnancy Act, Act No. 92 of 1996 brought many challenges for the registered nurses/midwife assisting in the termination of pregnancy. In the gynaecological wards at a tertiary level hospital, registered nurses/midwives assist with the termination of pregnancies for women in the second ...
Pye Seonaid M - - 2008
Imatinib has now been in use for almost 10 years. Despite this cumulative experience, little is known about its effects on pregnancy; as a result, there are few published data to facilitate the counseling of women who conceive while taking imatinib. The results we now present provide information which may ...
Prasad Sudha - - 2009
OBJECTIVES: To assess the efficacy, safety, and acceptability of early termination of pregnancy by vaginal administration of a single dose of misoprostol. SETTING: Healthy women seeking abortion in an institutional research environment in a tertiary-care hospital. DESIGN: Prospective randomized controlled clinical trial. PARTICIPANTS: One hundred forty women seeking termination of ...
Lawton Beverley A - - 2008
BACKGROUND: Sexually transmitted infections increase the risk of postoperative complications after termination of pregnancy. Mycoplasma genitalium is sexually transmitted and associated with adverse clinical outcomes in both males and females. The prevalence of M. genitalium is not yet known in New Zealand women or among women presenting for termination of ...
Pasquini L - - 2008
We report our experience with intracardiac administration of potassium chloride as safe and effective method for late termination of pregnancy (TOP) and to document the indications for feticide in a major tertiary unit. During the study period (January 2000 and December 2005), 239 late terminations of pregnancy were performed at ...
Fawole Adeniran O - - 2008
BACKGROUND: Although supported by research evidence, misoprostol for induction of labour remains contentious. OBJECTIVE: To assess perception and practice of obstetricians regarding use of misoprostol for labour induction. METHODOLOGY: Cross-sectional questionnaire-based survey of Senior Registrars and Consultant Obstetricians in southwestern Nigeria. RESULTS: One hundred and six questionnaires were completed (52.8% ...
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