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Sadakata Hisanobu H Department of Obstetrics and Gynecology, Gunma University Graduate School of Medicine, Gunma, - - 2014
A 43-year-old woman (gravida 0, para 0) was diagnosed with thyroid carcinoma and had been receiving radioactive iodine for remnant ablation. Eventually, her pregnant status became apparent; during radiation, she was at 5 gestational weeks. She decided to continue the pregnancy and delivered a boy of 2362 g at 37 gestational ...
Maynard Matthew R MR J Crayton Pruitt Family Departmet of Biomedical Engineering, University of Florida, Gainesville, FL - - 2014
Efforts to assess in utero radiation doses and related quantities to the developing fetus should account for the presence of the surrounding maternal tissues. Maternal tissues can provide varying levels of protection to the fetus by shielding externally-emitted radiation or, alternatively, can become sources of internally-emitted radiation following the biokinetic ...
Benchamanon R R Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University , Bangkok , - - 2014
The purpose of this study was to examine the effectiveness, side-effects and acceptability of a single dose of oral misoprostol 600 μg for treatment of 1st trimester pregnancy failure. A prospective descriptive study was conducted on pregnant women of < 13 weeks' gestation, diagnosed as 1st trimester pregnancy failure. Patients ...
Zetstra-van der Woude Priscilla A PA Unit of PharmacoEpidemiology and PharmacoEconomics, Department of Pharmacy, University of Groningen, Groningen, The - - 2014
Low-dose folic acid supplementation (0.5 mg) taken during pregnancy has been associated with an increased risk for childhood asthma. The effect of high-dose folic acid (5 mg) advised to women at risk for having a child with neural tube defect has not been assessed so far. Our aim was to investigate the ...
Aldámiz-Echevarría Luis L Division of Metabolism, Cruces University Hospital , Barakaldo, Bizkaia , Spain - - 2014
Abstract Purpose: A woman with phenylketonuria (PKU) was diagnosed through neonatal screening, her PAH mutation was p.V388M/p.I65T, for which she received treatment with phenylalanine restriction, and was administered oral sapropterin dihydrochloride (6R-BH4) from the age of thirty. The purpose of this article is to describe the treatment with BH4 during ...
Chan Wee-Shian WS Vancouver - - 2014
Objective: To present an approach, based on current evidence, for the diagnosis, treatment, and thromboprophylaxis of venous thromboembolism in pregnancy and postpartum. Evidence: Published literature was retrieved through searches of PubMed, Medline, CINAHL, and The Cochrane Library from November 2011 to July 2013 using appropriate controlled vocabulary (e.g. pregnancy, venous ...
Hon Ms M University Hospital Southampton NHS Foundation Trust, Southampton, - - 2014
: A 37 year old multip presented at 34 weeks with shortness of breath on exertion and yellowed sclera. Investigations showed her to have a haemolytic anaemia (Hb 56 g/l) and abnormal LFTs (ALT 67, bilirubin 58). Liver imaging and virology were normal. The haematologists recommended a bone marrow biopsy ...
Mohamedally Smm S University of Leicester, Medical School, Leicester, - - 2014
NICE recommends that patients should be informed about the importance of maintaining Vitamin D levels during pregnancy. To ensure that 100% of pregnant women are aware of the need to supplement Vitamin D during pregnancy. We created a cross sectional survey of pregnant women to assess knowledge and intake of ...
Sarween N N University Hospital Birmingham, Birmingham, - - 2014
Fibromuscular dysplasia (FMD) is the most frequent cause of renovascular hypertension in women of fertile age. We present a 36 year old identified in early pregnancy with severe resistant hypertension caused by bilateral FMD. A 36-year-old primigravida with no past medical history was referred to the renal-obstetric services at 11 ...
Eissa Aa A Royal Free Hospital Hampstead NHS Foundation Trust, London, - - 2014
: Maternal hypothyroidism complicates 2-5% of pregnancies. Thyroxine (T₄) replacement is known to improve obstetric outcomes (rates of miscarriage, premature labour and low birth weight), although there is no evidence that it modifies neurological development in the offspring. This descriptive study looks at the thyroxine requirements, trends in Thyroid Stimulating ...
Wu Wenming W Institute of Digestive Diseases, Chinese PLA General Hospital, Beijing, China; Department of Gastroenterology and Hepatology, General Hospital of Ji'nan Military Command Region, Ji'nan, - - 2014
Gallstone diseases are common during pregnancy. In most cases, patients are asymptomatic and do not require any treatment. However, choledocholithiasis, cholangitis, and gallstone pancreatitis may potentially become life-threatening for both mother and fetus and often require urgent intervention. Although endoscopic retrograde cholangiopancreatography (ERCP) has become the standard technique for removing ...
Lee Kyung-Hee KH Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, - - 2014
To evaluate whether letrozole incorporated in a gonadotrophin-releasing hormone (GnRH) antagonist multiple dose protocol (MDP) improved controlled ovarian stimulation (COS) and in vitro fertilization (IVF) results in poor responders who underwent IVF treatment. In this retrospective cohort study, a total of 103 consecutive IVF cycles that were performed during either ...
Atkinson Paul P Royal Hospital for Women, Randwick NSW, - - 2014
Gonadotropin releasing hormone agonist triggers are very effective in eliminating early-onset ovarian hyperstimulation syndrome (OHSS). However, in most studies they result in inferior pregnancy rates compared to hCG triggers in fresh autologous transfers. This is not due to an effect on embryo quality but rather due to inadequate corpus luteum ...
Kupryś-Lipińska Izabela I Department of Internal Medicine, Asthma and Allergy, Norbert Barlicki Memorial University Hospital No 1 in Lodz, Medical University of Lodz, Poland. Head of Department: Prof. Piotr Kuna MD, - - 2014
The article presents case reports of 2 women who became pregnant during therapy with omalizumab. Both subjects suffered from very severe asthma and were treated chronically with all available medications including systemic steroids (first - 20 mg prednisolone/day, second - 40 mg prednisolone/day). Both were enrolled into treatment with omalizumab ...
Govaere Jlj J Department of Reproduction, Obstetrics and Herd Health, Ghent University, Ghent, - - 2014
Deep intra-uterine insemination is commonly accepted as a routine procedure for artificial insemination in horses. The motives and principles of deep insemination are well described, but the equipment used may differ. In this trial, the efficiency of two different insemination pipettes for deep intra-uterine insemination in the mare was compared ...
David Natan de ND Centro de Estudos em Células Tronco, Terapia Celular e Genética Toxicológica (CeTroGen), Núcleo de Hospital Universitário (NHU), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Mato Grosso do Sul, Brasil; Programa de Mestrado em Farmácia, Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Mato Grosso do Sul, - - 2014
Gochnatia polymorpha ssp. floccosa is used in folk medicine to treat inflammation and infections. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly consumed medications during pregnancy in women with inflammatory diseases. However, the relationship between the use of NSAIDs and the risk of miscarriage and birth defects and/or benefits is ...
Yesiltepe Mutlu Gul G Division of Pediatric Endocrinology and Diabetes, School of Medicine, Kocaeli University, Kocaeli, - - 2014
Aim/Background: Vitamin D supplementation during pregnancy is a well-accepted recommendation worldwide; however, the debate about the correct dose is ongoing. We aimed to compare daily doses of 600, 1,200, and 2,000 IU in this randomized, controlled study. Methods: The study group consisted of 91 pregnant women aged 16-42 years admitted ...
Bellone Michael M Division of Transfusion Medicine, Department of Pathology, North Shore University Hospital and Hofstra North Shore-LIJ School of Medicine, Manhasset, New - - 2014
Maternal D alloimmunization detected in early gestation requires aggressive intervention to prevent severe fetal anemia. An intrauterine transfusion (IUT) is indicated to prevent fetal death once severe fetal anemia has been detected, but is not without risk. Protocols combining therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) have been described, ...
Vostrotin V V - - 2014
Abstract Purpose: The estimation of plutonium fetal transfer and the calculation of individual in utero and postnatal doses for the Mayak Production Association (PA) offspring cohort. Materials and methods: The model developed by the International Commission on Radiological Protection (ICRP) for the transfer of plutonium to the fetus following maternal ...
Osborne Lauren M LM Division of Behavioral Medicine, Department of Psychiatry, Columbia University Medical Center, 630 W. 168th Street, PH 1540G, New York, NY, 10032, USA, - - 2014
Managing depression and anxiety during pregnancy and the postpartum period is challenging. Both pharmacological treatment and the lack thereof can pose threats to a fetus. SSRIs are the drugs of choice for use during pregnancy, but there is considerable evidence for the safety and efficacy of older antidepressants during pregnancy ...
Brady Paula C PC Department of Obstetrics, Gynecology and Reproductive Biology, Division of Reproductive Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, - - 2014
To evaluate the association between serum progesterone (P) levels on the day of embryo transfer (ET) and pregnancy rates in fresh donor IVF/ICSI cycles. Fresh donor cycles with day 3 ET from 10/2007 to 8/2012 were included (n = 229). Most cycles (93 %) were programmed with a gonadotropin releasing hormone (GnRH) agonist; ...
Sfakianaki Anna K AK Sections of Maternal-Fetal Medicine and Family Planning, Department Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 333 Cedar St, PO Box 208063, New Haven, CT 06520 USA. - - 2014
Objectives- Induction of fetal demise before second-trimester termination is performed for a number of reasons. One method for inducing fetal demise is via sonographically guided intracardiac potassium chloride (KCl) injection. We performed a retrospective cohort study to determine the efficacy and safety of intracardiac KCl injection as a method of ...
Luke Barbara B Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing, Michigan. Electronic address: - - 2014
To evaluate factors associated with monozygosity (MZ) (number of fetal heartbeats on early ultrasound greater than the number of embryos transferred) and the risk of recurrence in subsequent pregnancies using a national assisted reproduction database. Historical cohort study. Clinic-based data. 197,327 pregnancies (including 2,824 with evidence of MZ) from cycles ...
Onyebuchi Azubike Kanario AK Department of Obstetrics and Gynecology, Federal Teaching Hospital, Abakaliki, - - 2014
Intermittent preventive treatment of malaria for pregnant women (IPTp) is a very important strategy for the control of malaria in pregnancy in malaria-endemic tropical countries, where mosquito bites easily occur during evening outdoor activities. Issues related to provision, cost, and acceptability may affect the use of IPTp in some developing ...
Jindal Rita R Department of Gynaecology and Obstetrics, Hindu Rao Hospital, New Delhi, - - 2014
A 22-year-old lactating mother presented with symptoms of uneasiness, palpitation, tachycardia and exophthalmos. She had an abdominal lump suggestive of 26 weeks uterine size but her urine pregnancy test was negative. Her thyroid profile was suggestive of hyperthyroidism. Gynaecological and ultrasonographic findings revealed a hydatidiform mole. She had a low β-human ...
Schramm Amelie M AM Department for Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, - - 2014
Preeclampsia, the onset of hypertension and proteinuria during pregnancy, is a common medical disorder with high maternal and fetal mortality and morbidity. The underlying pathology remains poorly understood and includes inflammation, endothelial dysfunction, and an unbalanced thromboxane A2/prostacyclin ratio. For women with systemic lupus erythematosus (SLE), particularly those with preexisting ...
Damen L L Division of Neonatology, Department of Pediatrics, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The - - 2014
Benzodiazepines are one of the most frequently prescribed psychotropic drugs during pregnancy. Despite the fact that these drugs have been in use for a long time, there is still debate about the safety for the developing fetus and neonate. We present a case of a newborn with an apparent life-threatening ...
Hosomi Jorge Kioshi JK Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, - - 2014
Drugs used in preterm labor (PTL) have side effects. Research into new tocolytic agents is recommended. The plant Bryophyllum pinnatum (Lam.) Oken (Kalanchoe pinnata (Lam.) Pers) is used in Anthroposophic Medicine for PTL, insomnia, and emotional disturbances. The aim of this study was to evaluate the effects of B. pinnatum ...
Weber-Schoendorfer Corinna C Pharmakovigilanz- und Beratungszentrum für Embryonaltoxikologie, Institute for Clinical Teratology and Drug Risk Assessment in Pregnancy, Charité Universitätsmedizin Berlin and Department of Mathematics, Beuth Hochschule für Technik Berlin (University of Applied Sciences), Berlin, - - 2013
Objective. There is increasing awareness of the potential impact of paternal exposures on pregnancy outcome. In particular this applies to MTX, which is used in low doses for the treatment of RA and other inflammatory diseases. MTX is associated with a specific pattern of malformations in fetuses of exposed women, ...
Bracken Hillary H Gynuity Health Projects, New York, NY 10010, USA. Electronic address: - - 2013
To assess whether buccal misoprostol is effective for the treatment of intrauterine fetal death. This double-blind randomized trial was conducted at five tertiary-level hospitals in the United States and Vietnam. One hundred fifty-three women with an intrauterine fetal death at 14-28 weeks of pregnancy received either 100 mcg buccal misoprostol ...
Backhausen Mette G - - 2013
Objective To investigate the extent to which Danish women attending antenatal care plan their pregnancies and to determine the association between pregnancy planning and the intake of folic acid, alcohol consumption and smoking habits prior to conception and before the 16th week of gestation. Methods A cross-sectional survey of 258 ...
Clark Crystal T - - 2013
Little information is available on the need for dosage changes for lamotrigine in pregnant women with bipolar disorder. The authors present new data on serial serum levels of lamotrigine in pregnant patients on lamotrigine monotherapy. They also review the epilepsy literature on use of lamotrigine during pregnancy. Lamotrigine serum samples ...
Martín María Cecilia MC From the Argentine Teratogenic Agents Information Service "Fetal Health", Argentine National Center of Medical Genetics, ANLIS "Malbrán", Buenos Aires, - - 2013
Methotrexate (MTX) is a potent teratogen when used in high doses for cáncer or termination of tubal pregnancy. In contrast, it has been perceived as safe when used once weekly at low dose for rheumatological conditions. A prospective observational scontrolled tudy of women exposed to low dose MTX. The control ...
Ticku Jonathan - - 2013
The management of acute lymphoblastic leukemia (ALL) during pregnancy requires treatment with high-dose chemotherapy that can pose risks to both the mother and fetus. Special consideration to chemotherapy regimen and its doses and to fetal gestational age at the time of chemotherapy administration should be taken in order to limit ...
Saraiva Joana - - 2013
Prolactinomas are a common cause of gonadal dysfunction and infertility. We present the case of a 38-year-old woman with history of amenorrhea and infertility. At seven weeks of pregnancy she presented neuro-ophthalmologic complaints of headaches, diplopia, and right ptosis. The work-up study revealed an invasive pituitary macroadenoma with a maximum ...
Ahmad Shema - - 2013
Pregnancy is a state of many hormonal changes that can make interpretation of thyroid function tests difficult. Measuring trimester-specific reference values of thyrotropin and free thyroxine is recommended. Because overt maternal hypothyroidism negatively affects the fetus, timely recognition and treatment are important. Women taking levothyroxine prepregnancy require a ≤50% dose ...
Kunnen A - - 2013
Periodontitis, mostly associated with Porphyromonas gingivalis, has frequently been related to adverse pregnancy outcomes. We therefore investigated whether lipopolysaccharides of P. gingivalis (Pg-LPS) induced pregnancy complications in the rat. Experiment 1: pregnant rats (day 14) received increasing Pg-LPS doses (0.0-50.0 μg kg(-1) bw; n = 2/3 p per dose). Maternal intra-aortic blood pressure, urinary albumin ...
Khalifeh A - - 2013
Unfractionated heparin has largely been replaced by low molecular weight heparin in the treatment and prevention of thrombosis and recurrent miscarriage in pregnancy. There is little information, however, about the efficacy and safety of tinzaparin, which has the advantage of being administered as a single daily dose. To evaluate the ...
Vajda Frank J - - 2013
To study the relationships between maternal valproate dose in pregnancy and the pattern of various fetal malformations. Analysis of data in the Australian Register of Antiepileptic Drugs in Pregnancy collected from 1999 to 2012. The specific type of fetal malformation in offspring exposed to valproate in utero was correlated with ...
Onyeneho Nkechi G - - 2013
To investigate the characteristics of women in Nigeria who are likely to take sulfadoxine/pyrimethamine (SP) as recommended for the prevention of malaria in pregnancy to reduce maternal and child mortality rates. A cross-sectional survey of 1380 women was conducted using a structured questionnaire. The women had given birth within 6months ...
Patil Avinash S AS Department of Obstetrics & Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA. - - 2013
Romiplostim, a thrombopoietin mimetic, is a novel therapeutic option for patients with chronic immune thrombocytopenic purpura. We report on the effects of romiplostim use throughout pregnancy. A 28-year-old primigravid woman with chronic immune thrombocytopenic purpura initiated a planned pregnancy on romiplostim. The second and third trimesters were marked by a ...
Ringelstein M - - 2013
Neuromyelitis optica (NMO) predominantly affects women, some in childbearing age, and requires early therapeutic intervention to prevent disabling relapses. We report an anti-AQP4 antibody-seropositive patient who became pregnant seven months after low-dose (100 mg) rituximab application. Pregnancy showed no complications, and low-dose rituximab restarted two days after delivery resulted in ...
Uyar Ibrahim - - 2013
To evaluate ovarian reserve in women with ectopic pregnancy treated with single-dose systemic methotrexate in the early post-treatment period. Prospective study. Women's health education and research hospital. Eighty-two patients with ectopic pregnancy and 80 healthy women in the same age group were included in the study. Of the 82 patients, ...
McDowell Simon - - 2013
Clomiphene citrate is a widely used treatment for ovulatory dysfunction in women seeking pregnancy. The major adverse consequence of clomiphene use is the increased risk of multiple and higher-order multiple pregnancy. Mechanisms for multiple pregnancy include dosing variation, adjuvant therapies, pretreatment weight loss and a cumulative effect of multiple clomiphene ...
Kriplani Alka - - 2013
Background & objectives: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Prophylactic oral iron is recommended during pregnancy to meet the increased requirement. In India, women become pregnant with low baseline haemoglobin level resulting in high incidence of moderate to severe anaemia in pregnancy where oral ...
Ozkan Mehmet - - 2013
Prosthetic valve thrombosis (PVT) during pregnancy is life-threatening for mother and fetus, and the treatment of this complication is unclear. Cardiac surgery in pregnancy is associated with very high maternal and fetal mortality and morbidity. Thrombolytic therapy (TT) has been rarely used in these patients. The aim of this study ...
Gutman Julie - - 2013
Background. Malaria in pregnancy (MIP) is associated with low birth weight (LBW) and increased perinatal mortality, especially among primigravidae. Despite increasing prevalence of malaria parasite resistance to sulfadoxine-pyrimethamine (SP), SP continues to be recommended for intermittent preventive treatment in pregnancy (IPTp).Methods. HIV-uninfected women were enrolled upon delivery. Data on number of SP ...
Bennardello Francesco - - 2013
In 2010, the Italian Society of Immunohaematology and Transfusion Medicine (SIMTI) carried out a survey of the incidence of haemolytic disease of the newborn (HDN) and the prevention of HDN caused by anti-Rh(D) in Italian Transfusion Structures (TS). A questionnaire divided into the following five sections was administered: (i) types ...
Cossette Benoit - - 2013
BACKGROUND: Asthma during pregnancy usually requires treatment with controller medications about which more safety information is needed. The objectives are to assess the impact of the use of long-acting β2-agonists (LABAs) and the dose of inhaled corticosteroids (ICSs) during pregnancy on the prevalence of low birth weight (LBW), preterm birth ...
Kalogerakos K - - 2013
Breast cancer constitutes the first gynaecological malignancy in pregnancy with a frequency of 1 : 3,000 - 10,000 pregnancies. Pregnancy itself does not seem to affect the odds of developing breast cancer or its prognosis. Breast ultrasonography constitutes the diagnostic method of choice, whereas magnetic resonance imaging (MRI) can be ...
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