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David Natan de ND Centro de Estudos em Células Tronco, Terapia Celular e Genética Toxicológica (CeTroGen), Núcleo de Hospital Universitário (NHU), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Mato Grosso do Sul, Brasil; Programa de Mestrado em Farmácia, Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, Mato Grosso do Sul, - - 2014
Gochnatia polymorpha ssp. floccosa is used in folk medicine to treat inflammation and infections. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly consumed medications during pregnancy in women with inflammatory diseases. However, the relationship between the use of NSAIDs and the risk of miscarriage and birth defects and/or benefits is ...
Yesiltepe Mutlu Gul G Division of Pediatric Endocrinology and Diabetes, School of Medicine, Kocaeli University, Kocaeli, - - 2014
Aim/Background: Vitamin D supplementation during pregnancy is a well-accepted recommendation worldwide; however, the debate about the correct dose is ongoing. We aimed to compare daily doses of 600, 1,200, and 2,000 IU in this randomized, controlled study. Methods: The study group consisted of 91 pregnant women aged 16-42 years admitted ...
Bellone Michael M Division of Transfusion Medicine, Department of Pathology, North Shore University Hospital and Hofstra North Shore-LIJ School of Medicine, Manhasset, New - - 2014
Maternal D alloimmunization detected in early gestation requires aggressive intervention to prevent severe fetal anemia. An intrauterine transfusion (IUT) is indicated to prevent fetal death once severe fetal anemia has been detected, but is not without risk. Protocols combining therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIG) have been described, ...
Vostrotin V V - - 2014
Abstract Purpose: The estimation of plutonium fetal transfer and the calculation of individual in utero and postnatal doses for the Mayak Production Association (PA) offspring cohort. Materials and methods: The model developed by the International Commission on Radiological Protection (ICRP) for the transfer of plutonium to the fetus following maternal ...
Osborne Lauren M LM Division of Behavioral Medicine, Department of Psychiatry, Columbia University Medical Center, 630 W. 168th Street, PH 1540G, New York, NY, 10032, USA, - - 2014
Managing depression and anxiety during pregnancy and the postpartum period is challenging. Both pharmacological treatment and the lack thereof can pose threats to a fetus. SSRIs are the drugs of choice for use during pregnancy, but there is considerable evidence for the safety and efficacy of older antidepressants during pregnancy ...
Brady Paula C PC Department of Obstetrics, Gynecology and Reproductive Biology, Division of Reproductive Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, - - 2014
To evaluate the association between serum progesterone (P) levels on the day of embryo transfer (ET) and pregnancy rates in fresh donor IVF/ICSI cycles. Fresh donor cycles with day 3 ET from 10/2007 to 8/2012 were included (n = 229). Most cycles (93 %) were programmed with a gonadotropin releasing hormone (GnRH) agonist; ...
Sfakianaki Anna K AK Sections of Maternal-Fetal Medicine and Family Planning, Department Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 333 Cedar St, PO Box 208063, New Haven, CT 06520 USA. - - 2014
Objectives- Induction of fetal demise before second-trimester termination is performed for a number of reasons. One method for inducing fetal demise is via sonographically guided intracardiac potassium chloride (KCl) injection. We performed a retrospective cohort study to determine the efficacy and safety of intracardiac KCl injection as a method of ...
Luke Barbara B Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing, Michigan. Electronic address: - - 2014
To evaluate factors associated with monozygosity (MZ) (number of fetal heartbeats on early ultrasound greater than the number of embryos transferred) and the risk of recurrence in subsequent pregnancies using a national assisted reproduction database. Historical cohort study. Clinic-based data. 197,327 pregnancies (including 2,824 with evidence of MZ) from cycles ...
Weber-Schoendorfer Corinna C Pharmakovigilanz- und Beratungszentrum für Embryonaltoxikologie, Institute for Clinical Teratology and Drug Risk Assessment in Pregnancy, Charité Universitätsmedizin Berlin and Department of Mathematics, Beuth Hochschule für Technik Berlin (University of Applied Sciences), Berlin, - - 2013
Objective. There is increasing awareness of the potential impact of paternal exposures on pregnancy outcome. In particular this applies to MTX, which is used in low doses for the treatment of RA and other inflammatory diseases. MTX is associated with a specific pattern of malformations in fetuses of exposed women, ...
Bracken Hillary H Gynuity Health Projects, New York, NY 10010, USA. Electronic address: - - 2013
To assess whether buccal misoprostol is effective for the treatment of intrauterine fetal death. This double-blind randomized trial was conducted at five tertiary-level hospitals in the United States and Vietnam. One hundred fifty-three women with an intrauterine fetal death at 14-28 weeks of pregnancy received either 100 mcg buccal misoprostol ...
Backhausen Mette G - - 2013
Objective To investigate the extent to which Danish women attending antenatal care plan their pregnancies and to determine the association between pregnancy planning and the intake of folic acid, alcohol consumption and smoking habits prior to conception and before the 16th week of gestation. Methods A cross-sectional survey of 258 ...
Clark Crystal T - - 2013
Little information is available on the need for dosage changes for lamotrigine in pregnant women with bipolar disorder. The authors present new data on serial serum levels of lamotrigine in pregnant patients on lamotrigine monotherapy. They also review the epilepsy literature on use of lamotrigine during pregnancy. Lamotrigine serum samples ...
Martín María Cecilia MC From the Argentine Teratogenic Agents Information Service "Fetal Health", Argentine National Center of Medical Genetics, ANLIS "Malbrán", Buenos Aires, - - 2013
Methotrexate (MTX) is a potent teratogen when used in high doses for cáncer or termination of tubal pregnancy. In contrast, it has been perceived as safe when used once weekly at low dose for rheumatological conditions. A prospective observational scontrolled tudy of women exposed to low dose MTX. The control ...
Ticku Jonathan - - 2013
The management of acute lymphoblastic leukemia (ALL) during pregnancy requires treatment with high-dose chemotherapy that can pose risks to both the mother and fetus. Special consideration to chemotherapy regimen and its doses and to fetal gestational age at the time of chemotherapy administration should be taken in order to limit ...
Saraiva Joana - - 2013
Prolactinomas are a common cause of gonadal dysfunction and infertility. We present the case of a 38-year-old woman with history of amenorrhea and infertility. At seven weeks of pregnancy she presented neuro-ophthalmologic complaints of headaches, diplopia, and right ptosis. The work-up study revealed an invasive pituitary macroadenoma with a maximum ...
Ahmad Shema - - 2013
Pregnancy is a state of many hormonal changes that can make interpretation of thyroid function tests difficult. Measuring trimester-specific reference values of thyrotropin and free thyroxine is recommended. Because overt maternal hypothyroidism negatively affects the fetus, timely recognition and treatment are important. Women taking levothyroxine prepregnancy require a ≤50% dose ...
Kunnen A - - 2013
Periodontitis, mostly associated with Porphyromonas gingivalis, has frequently been related to adverse pregnancy outcomes. We therefore investigated whether lipopolysaccharides of P. gingivalis (Pg-LPS) induced pregnancy complications in the rat. Experiment 1: pregnant rats (day 14) received increasing Pg-LPS doses (0.0-50.0 μg kg(-1) bw; n = 2/3 p per dose). Maternal intra-aortic blood pressure, urinary albumin ...
Khalifeh A - - 2013
Unfractionated heparin has largely been replaced by low molecular weight heparin in the treatment and prevention of thrombosis and recurrent miscarriage in pregnancy. There is little information, however, about the efficacy and safety of tinzaparin, which has the advantage of being administered as a single daily dose. To evaluate the ...
Vajda Frank J - - 2013
To study the relationships between maternal valproate dose in pregnancy and the pattern of various fetal malformations. Analysis of data in the Australian Register of Antiepileptic Drugs in Pregnancy collected from 1999 to 2012. The specific type of fetal malformation in offspring exposed to valproate in utero was correlated with ...
Patil Avinash S - - 2013
Romiplostim, a thrombopoietin mimetic, is a novel therapeutic option for patients with chronic immune thrombocytopenic purpura. We report on the effects of romiplostim use throughout pregnancy. A 28-year-old primigravid woman with chronic immune thrombocytopenic purpura initiated a planned pregnancy on romiplostim. The second and third trimesters were marked by a ...
Onyeneho Nkechi G - - 2013
To investigate the characteristics of women in Nigeria who are likely to take sulfadoxine/pyrimethamine (SP) as recommended for the prevention of malaria in pregnancy to reduce maternal and child mortality rates. A cross-sectional survey of 1380 women was conducted using a structured questionnaire. The women had given birth within 6months ...
Ringelstein M - - 2013
Neuromyelitis optica (NMO) predominantly affects women, some in childbearing age, and requires early therapeutic intervention to prevent disabling relapses. We report an anti-AQP4 antibody-seropositive patient who became pregnant seven months after low-dose (100 mg) rituximab application. Pregnancy showed no complications, and low-dose rituximab restarted two days after delivery resulted in ...
Uyar Ibrahim - - 2013
To evaluate ovarian reserve in women with ectopic pregnancy treated with single-dose systemic methotrexate in the early post-treatment period. Prospective study. Women's health education and research hospital. Eighty-two patients with ectopic pregnancy and 80 healthy women in the same age group were included in the study. Of the 82 patients, ...
McDowell Simon - - 2013
Clomiphene citrate is a widely used treatment for ovulatory dysfunction in women seeking pregnancy. The major adverse consequence of clomiphene use is the increased risk of multiple and higher-order multiple pregnancy. Mechanisms for multiple pregnancy include dosing variation, adjuvant therapies, pretreatment weight loss and a cumulative effect of multiple clomiphene ...
Kriplani Alka - - 2013
Background & objectives: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Prophylactic oral iron is recommended during pregnancy to meet the increased requirement. In India, women become pregnant with low baseline haemoglobin level resulting in high incidence of moderate to severe anaemia in pregnancy where oral ...
Ozkan Mehmet - - 2013
Prosthetic valve thrombosis (PVT) during pregnancy is life-threatening for mother and fetus, and the treatment of this complication is unclear. Cardiac surgery in pregnancy is associated with very high maternal and fetal mortality and morbidity. Thrombolytic therapy (TT) has been rarely used in these patients. The aim of this study ...
Gutman Julie - - 2013
Background. Malaria in pregnancy (MIP) is associated with low birth weight (LBW) and increased perinatal mortality, especially among primigravidae. Despite increasing prevalence of malaria parasite resistance to sulfadoxine-pyrimethamine (SP), SP continues to be recommended for intermittent preventive treatment in pregnancy (IPTp).Methods. HIV-uninfected women were enrolled upon delivery. Data on number of SP ...
Bennardello Francesco - - 2013
In 2010, the Italian Society of Immunohaematology and Transfusion Medicine (SIMTI) carried out a survey of the incidence of haemolytic disease of the newborn (HDN) and the prevention of HDN caused by anti-Rh(D) in Italian Transfusion Structures (TS). A questionnaire divided into the following five sections was administered: (i) types ...
Cossette Benoit - - 2013
BACKGROUND: Asthma during pregnancy usually requires treatment with controller medications about which more safety information is needed. The objectives are to assess the impact of the use of long-acting β2-agonists (LABAs) and the dose of inhaled corticosteroids (ICSs) during pregnancy on the prevalence of low birth weight (LBW), preterm birth ...
Kalogerakos K - - 2013
Breast cancer constitutes the first gynaecological malignancy in pregnancy with a frequency of 1 : 3,000 - 10,000 pregnancies. Pregnancy itself does not seem to affect the odds of developing breast cancer or its prognosis. Breast ultrasonography constitutes the diagnostic method of choice, whereas magnetic resonance imaging (MRI) can be ...
Gaviraghi A - - 2013
In buffaloes, AI with sexed semen is not fully optimized, and the procedure has only been performed using the approach currently in use for cattle. The objective of the present work was to compare the pregnancy rates in Mediterranean Italian buffalo cows inseminated with sexed frozen-thawed semen at 2, 4, ...
Yu Xiaohui - - 2013
In this study, we researched the pattern of thyroid function of subclinical hypothyroid (SCH) women with levothyroxine (LT4) throughout pregnancy and determined the optimal dosages of LT4 for such women. 56 SCH pregnant women were followed regularly prospectively. They were divided into three groups: group A (n = 29. Baseline TSH between ...
Krissi Haim - - 2013
OBJECTIVE: To evaluate potential risk factors at admission for failed single-dose methotrexate injection in women with ectopic pregnancy. METHODS: File review of a tertiary medical center in Israel yielded 102 consecutive patients with ectopic pregnancy initially treated with single-dose methotrexate. Overall successful treatment was defined as normalization of human chorionic ...
Wortman Alison - - 2013
: Selective embolization in pregnancy for treatment of renal hemorrhage has been reported infrequently in the literature; the possibility of minimizing radiation dose to the fetus by using dose-sparing fluoroscopy techniques is not commonly appreciated by the obstetric community. : We describe performing partial renal embolization with the use of ...
Zhao Shuquan - - 2013
Bilobar thyroid agenesis is one of rare diseases. Genetic and environmental factors may associate with bilobar thyroid agenesis. But the mechanism is still not completely understood. It had been showed that I-131 administration during pregnancy may induce thyroid dysfunction in newborn. Here we reported a case of female hospital staff ...
Yasa C - - 2013
The aim was to investigate the impact of low-dose letrozole usage along with gonadotropin treatment in vitro fertilization (IVF) cycles in comparison to gonadotropin treatment alone. Fifty patients were prospectively included in this randomized study and were divided into two groups. Age, demographic features, causes, and period of infertility were ...
Rouzi A A - - 2013
Termination of pregnancy in the second trimester for an intrauterine death of a fetus with anencephaly in a woman with previous three cesarean sections is a difficult clinical dilemma. A 34-year-old, gravida 4, para 3 woman was admitted at 20 weeks gestation for termination of pregnancy due to intrauterine death ...
de Carvalho L P Fogarolli - - 2013
To evaluate the morphological aspects in rats subjected to an association of the antiretroviral drugs zidovudine/lopinavir/ritonavir in different doses administered throughout the gestational period. Forty pregnant rats were randomly allocated into four groups: control (Ctrl) and experimental (Exp1, Exp2, and Exp3), which received zidovudine/lopinavir/ritonavir in the doses of 10/13.3/3.3, 30/39.9/9.9, ...
Yilmaz Nafiye - - 2012
BACKGROUND: In recent years, it has become evident that ovarian stimulation, although a central component of in vitro fertilization (IVF), may itself has detrimental effects on oogenesis, embryo quality, endometrial receptivity, and perhaps also perinatal outcomes. OBJECTIVE: To evaluate the effect of higher gonadotrophin dose on clinical pregnancy rate in ...
Cleary Bj - - 2012
AIMS: This study aimed to i) describe methadone dosing before, during and after pregnancy, ii) to compare the incidence of neonatal abstinence syndrome (NAS) between those with dose decreases and those with steady or increasing doses and iii) to describe prescribed medication use among opioid-dependent pregnant women. DESIGN: Prospective cohort ...
Fierro Sergio - - 2012
This review considers the use of prostaglandin F(2α) and its synthetic analogues (PG) for controlling the estrous cycle of the ewe. Aspects such as phase of the estrus cycle, PG analogues, PG doses, ovarian follicle development pattern, CL formation, progesterone synthesis, ovulation rate, sperm transport, embryo quality, and fertility rates ...
Kasum Miro - - 2012
The aim of the present study was to analyze retrospectively the safety and success rates of single- and two-dose methotrexate (MTX) protocols for the treatment of hemodynamically stable cases of ectopic pregnancy at University Department of Gynecology and Obstetrics, Zagreb University Hospital Center, during a five-year period. The study evaluated ...
Cardonick Elyce - - 2012
: To estimate the effect of dose-dense chemotherapy during pregnancy on maternal and neonatal outcomes. : This is a retrospective cohort study in which women were identified from the international Cancer and Pregnancy Registry at Cooper Medical School at Rowan University in Camden, New Jersey. A chart analysis was completed ...
De Sancho Maria T - - 2012
To assess the rate and type of maternal and infant complications among pregnant women receiving low-molecular-weight heparin (LMWH). Retrospective study of pregnant women on LMWH referred to two university hematology clinics from January 2001 to December 2010. We recorded the number of pregnancies, indication, dose and dose adjustments for LMWH, ...
Ramprasad Menaka - - 2012
Thyroid disorders are common in pregnancy and the most common disorder is subclinical hypothyroidism. Due to the complex hormonal changes during pregnancy, it is important to remember that thyroxine requirements are higher in pregnancy. According to recent American Thyroid Association (ATA) guidelines, the recommended reference ranges for TSH are 0.1 ...
Salisbury Amy L - - 2012
To determine pre- and post-dosing effects of prenatal methadone compared to buprenorphine on fetal wellbeing. A secondary analysis of data derived from the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a double-blind, double-dummy, randomized clinical trial. Six United States sites and one European site that provided comprehensive opioid-dependence treatment ...
Devarajah S - - 2012
The number of opiate users is well documented; however, the severity of opiate use has received little attention. This retrospective study in a North of England hospital updates the progression in the severity of addiction in pregnancy. Patients treated were reviewed and the doses of prescribed methadone documented. Historical data ...
Wang Zhengguang - - 2012
Three experiments were conducted to examine the effects of green tea polyphenols (GTP) during IVM and IVC on apoptosis and relative transcript abundance (RA) of three genes controlling antioxidant enzymes, as well as subsequent pregnancy rates. In experiment 1, oocytes were matured in the presence of 0, 10, 15, or ...
Ribot Blanca - - 2012
Currently, there is no consensus regarding the optimum iron supplementation during pregnancy. The aim of this study is to evaluate the effect of different iron supplementation doses (including no supplementation) during pregnancy on the iron status of the mother and on the health of the neonate. A longitudinal study was ...
Poulasouchidou Maria K - - 2012
To examine whether the concentrations of maternal serum TSH and free thyroxine (fT4) through pregnancy, the presence of thyroid autoimmunity (TAI) or the dose of levo-thyroxine (LT4) replacement can predict the occurrence of maternal or fetal/neonatal complications in pregnant women treated for maternal hypothyroidism. The study included 92 women with ...
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