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Results 201 - 250 of 1082
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Luks Andrew M - - 2007
An obese body habitus may interfere with diagnosis of potentially life-threatening conditions. This report describes an obese woman who presented with acute hypoxemic respiratory failure and diffuse infiltrates. Her body habitus disguised her parturient abdomen and she could not provide a history because she was intubated and paralysed. Only after ...
Smart D J - - 2008
AIM: The primary purpose of this study was to investigate the relationship between the pre-game to post-game changes in creatine kinase concentration (Delta[CK]) and impact-related game statistics in elite rugby union players. METHODS: Twenty-three elite male rugby union players each provided interstitial fluid samples obtained via electrosonophoresis (ESoP) 210 min ...
Luksha Leanid - - 2008
We hypothesized that in preeclampsia (PE), contribution of endothelium-derived hyperpolarizing factor (EDHF) and the mechanism/s of its action differ from that in normal pregnancy (NP). We aimed to assess endothelial function and morphology in arteries from NP and PE with particular focus on EDHF. Arteries ( approximately 200 mum) were ...
Miller Raymond S - - 2007
We evaluated the influence of maternal pre-pregnancy body mass index (BMI), based on reported pre-pregnancy weight and height, on blood pressure (BP) levels during pregnancy by using information from a prospective cohort of 1733 women recruited before 20 weeks' gestation. Maternal antenatal BP values were abstracted from medical records, and ...
Feske Steven K - - 2007
Although pregnancy-associated stroke is uncommon, the risk of stroke is greatly increased above the low baseline rate in young patients during late pregnancy and, even more so, during the puerperium. Stroke is a major contributor to the serious morbidity and mortality of pregnancy. The physiological hormonally mediated changes in circulation, ...
Arechavaleta-Velasco F - - 2008
BACKGROUND: We demonstrated recently that adeno-associated virus-2 (AAV-2) DNA was detected significantly more frequently in placental trophoblast cells from cases of severe pre-eclampsia than from normal term deliveries. Here, we sought to determine if maternal AAV-2 infection early in pregnancy preceded adverse outcomes resulting from placental dysfunction. METHODS: We collected ...
van de Geijn Fleur E - - 2007
Both immunological and placental factors are involved in the pathogenesis of pre-eclampsia. The complement factor mannose-binding lectin (MBL) is associated with adverse pregnancy outcomes and has been suggested to play a role in abnormal placentation. We investigated whether MBL genotypes are associated with the systemic maternal syndrome pre-eclampsia. MBL2 gene ...
Bachour Adel - - 2008
OBJECTIVES: To evaluate pregnancy-associated sleep disorders, pregnancy outcomes and inflammatory markers in pre-eclampsia and normal pregnancy (control). PATIENTS AND METHODS: We studied 15 consecutive pre-eclamptic women and 14 controls. Pre-eclamptic women underwent overnight pulse oximetry and nasal pressure measurements at a university teaching hospital, and the sleep study for the ...
Rizzo Giuseppe - - 2008
OBJECTIVE: To compare the efficacy of uterine artery Doppler velocimetry and three-dimensional ultrasound placental volume calculation alone or in combination in predicting at 11-14 weeks of gestation those pregnancies who will develop pre-eclampsia. STUDY DESIGN: This was a prospective study of 348 nulliparous women scheduled for a routine prenatal ultrasound ...
Roopnarinesingh R - - 2007
Pre-eclampsia remains an enigma despite extensive research. It is a common obstetric disorder and has multi-system ramifications. Previous research has concluded that the parameters of forced spirometry remain unchanged in normal pregnancy compared with non-pregnant controls. This study revealed that pre-eclampsia significantly alters lung function and implies that non-pregnant spirometric ...
Ademuyiwa Oladipo - - 2007
To assess the antioxidant capacity of pregnant women in Ogun State, Nigeria. The activities of total superoxide dismutase (total SOD), manganese superoxide dismutase (Mn-SOD), catalase (CAT), glutathione transferase(GST), aminolevulinic acid dehydratase (ALAD), and the concentrations of glutathione (GSH), were determined in the plasma and red blood cells of non-pregnant (n=20), ...
Lakshmi R - - 2007
Postpartum eclampsia is a serious and unexpected complication. A relative increase in the incidence of postpartum eclampsia has been noted in the last few years. Late postpartum eclampsia, though initially controversial, is now recognised up to four weeks after delivery. We present such a case occurring in a 26-year-old woman. ...
Raijmakers Maarten T M - - 2008
OBJECTIVES: Glutathione, an intracellular tripeptide, functions in the protection of cells against free radicals and toxins of endogenous and exogenous origin. To maintain the intracellular redox status in presence of reactive oxygen species, glutathione (GSH) and other thiols are oxidized. The oxidative status of thiols is reflected by the free-to-oxidized ...
Rogers Mike S - - 2007
Pre-eclampsia is a multisystem disorder of pregnancy, usually characterized by the appearance of high blood pressure and the excretion of protein in the urine of a previously healthy woman. Symptoms and signs vary in intensity from woman to woman; from a borderline rise in blood pressure, to convulsions (eclampsia), stroke ...
Almeida John A - - 2007
Properly assessing the safety of pharmacological therapies for gastrointestinal conditions encountered during pregnancy is a challenge on account of both the often limited controlled data available and the potentially confounding effect of the underlying disorders requiring treatment on fetal outcomes. Here, the available data with regard to gastrointestinal disorders specific ...
Obed Sa - - 2007
Summary To find out the reproductive performance of patients in the immediate pregnancy following an eclampsia. Longitudinal survey. Obstetrics Unit of Department of Obstetrics and Gynaecology in a teaching hospital. Three hundred and ninety seven women whose previous pregnancies were complicated by eclampsia were followed up based on a schedule ...
Howarth C - - 2007
BACKGROUND: Maternal diabetes increases the risk of pre-eclampsia and abnormalities of fetal growth. We studied the additional impact of maternal vascular disease on these risks. METHODS: The first viable (> 23 weeks) pregnancies of 138 women with Type 1 diabetes mellitus (Type 1 DM), delivered between 1994 and 2003 at ...
Onderoglu Lutfu S - - 2007
Cortical blindness is a rare and dramatic complication of pre-eclampsia. The precise nature of the pathogenesis of this condition has not previously been understood. Three preeclamptic patients with unremarkable previous medical history presented with acute blindness between the 28th and 33rd weeks of pregnancy. They were all diagnosed as posterior ...
Houben Alphons J H M - - 2007
OBJECTIVE: To test the hypothesis that during pre-eclampsia microvascular function and structure are disturbed, which contributes to raised venular resistance. METHODS: The microcirculation of the skin and bulbar conjunctiva was studied in 11 women with preeclampsia and nine parous controls, both in the third trimester and 3 months postpartum. Using ...
Moura A N - - 2007
The aim of this study was to evaluate the benthic diatom composition from the estuary sediment in the Pernambuco State, based on 32 samples. Samples were collected monthly from September through December 1999 (dry period) and from April through July 2000 (rainy period) during four pre established sampling stations. Results ...
Odden Nancy - - 2007
This study is the first to report high molecular weight (HMW) adiponectin in newborns from normal and pre-eclamptic pregnancies (PE). Adiponectin is adversely related to Metabolic Syndrome-linked diseases such as obesity, dyslipidaemia, insulin resistance and hypertension. It is abundant in human plasma where it circulates as several characteristic multimeric forms ...
De Las Heras V - - 2007
OBJECTIVES: To study the management of pregnancy in multiple sclerosis (MS) patients on immunomodulatory therapy (IMT) in routine clinical practice and to analyze pregnancy outcomes and the clinical course of MS around pregnancy. METHODS: Retrospective, multicentric study in Spain in MS patients receiving IMT before conception and followed for at ...
Pryor-Koishi K - - 2007
OBJECTIVE: To characterise the follistatin-related gene (FLRG) in pre-eclampsia, one of the differentially expressed genes in pre-eclamptic placenta. DESIGN AND METHODS: We examined and compared the messenger RNA (mRNA) and protein levels of FLRG in placentas and maternal sera from women with uncomplicated pregnancy, and those with pre-eclampsia using real-time ...
Berends A L - - 2007
The STOX1 gene, identified as a candidate gene for pre-eclampsia in Dutch women, is placentally expressed and subject to imprinting with preferential transmission of the maternal allele. In our study, STOX1-Y153H frequencies were similar in 157 women with pre-eclampsia (65%) and in 157 controls (64%) from the general Dutch population. ...
Tskitishvili E - - 2008
The human tumor-associated antigen RCAS1 (receptor-binding cancer antigen expressed on SiSo cells) is considered to play a role in the escape of tumor cells from immune surveillance and, at the same time, participates in the inhibition of the maternal immune response during pregnancy. The aim of our study was to ...
Nishizawa Haruki - - 2007
PROBLEM: It has been demonstrated that allogeneic fetal rejection in normal pregnancy is prevented by placental indoleamine 2,3-dioxygenase (IDO). Further, an immunological etiology has been implicated in pre-eclampsia. METHOD OF STUDY: We examined the differences in placental IDO activity between normal and pre-eclamptic pregnancies. RESULTS: IDO mRNA expression and enzyme ...
Lakhdar H - - 2007
BACKGROUND: Chloasma, or melasma, is a pigmentary disorder that can affect between 50% and 70% of pregnant women. During pregnancy, chloasma does not require any particular treatment beside the use of an effective sunscreen and avoiding the use of any photosensitizing products or inappropriate skin care routine. However, there exist ...
Luo Zhong-Cheng - - 2007
Pre-eclampsia has been dubbed as 'a disease of primiparity'. However, the effects and mechanisms of the association of primiparity with pre-eclampsia have not been clearly defined. We conducted a systematic review of studies evaluating the effect of primiparity on the risk of pre-eclampsia, and studies (published between January 1966 and ...
Lie Rolv T - - 2007
Population-based data that cover reproductive health outcomes across two complete generations have recently become available in the Nordic countries. Such data enable estimation of recurrence risks from one generation to the next of different conditions such as birth defects or pre-eclampsia. Risks related to a singleton pregnancy involve the contribution ...
Rahman M A - - 2007
Eclampsia-a common pregnancy induced disorder that poses a great threat to the fetus secondary to the placental changes. Since placenta is mostly vascular organ, the present comparative study was designed to examine microscopic vascular changes as well as to observe their impact on the macroscopic dimensions of the placenta and ...
Brown M A - - 2007
OBJECTIVE: To estimate the rates of recurrence of pre-eclampsia or gestational hypertension in a subsequent pregnancy and to determine factors predictive of recurrence. DESIGN: Retrospective cohort study. SETTING: St George Public and Private Hospitals, teaching hospitals without neonatal intensive care units. PARTICIPANTS: A total of 1515 women with a diagnosis ...
Newhouse S M - - 2007
Highly purified (>99.99%) primary villous cytotrophoblasts from uncomplicated pregnancies and pregnancies complicated with intrauterine growth restriction (IUGR) alone, IUGR with pre-eclampsia (IUGR-PE) and PE alone were cultured for 5days and the extent of differentiation into syncytiotrophoblasts measured in terms of syncytialisation and secretion of chorionic gonadotropin (hCG) and placental lactogen ...
Askie Lisa M LM Centre for Perinatal Health Services Research, University of Sydney, Sydney, Australia. - - 2007
Pre-eclampsia is a major cause of mortality and morbidity during pregnancy and childbirth. Antiplatelet agents, especially low-dose aspirin, might prevent or delay pre-eclampsia, and thereby improve outcome. Our aim was to assess the use of antiplatelet agents for the primary prevention of pre-eclampsia, and to explore which women are likely ...
Rosenberg Karen R - - 2007
Preeclampsia/eclampsia is a dangerous condition unique to humans that is associated with an energetically expensive developing fetal brain and extremely invasive implantation of the trophoblast. We review here the evolutionary history of human pregnancy and childbirth to set a context for evolutionary hypotheses about the origin of preeclampsia. Humans are ...
Solomon G M - - 2007
BACKGROUND: Pesticide exposures and poisoning are common and generally under-reported in poorly resourced countries where women are mainly involved in agricultural work. Cases of organophosphate poisoning in pregnancy are unusual. CASE REPORT: A 22-year-old woman in her 29th week of pregnancy presented to King Edward VIII Hospital, Durban, South Africa ...
Germain Sarah J - - 2007
Systemic inflammatory responsiveness was studied in normal human pregnancy and its specific inflammatory disorder, pre-eclampsia. Compared with nonpregnancy, monocytes were primed to produce more TNF-alpha throughout normal pregnancy, more IL-12p70 in the first and second trimesters, and more IL-18 in the first trimester only. Intracellular cytokine measurements (TNF-alpha and IL12p70) ...
Brosens Ivo A - - 2007
BACKGROUND: We postulated that impaired endometrial differentiation in women with pelvic endometriosis predisposes for pre-eclampsia. METHODS: A retrospective case-control study set at the University of Ghent IVF centre. The incidence of pre-eclampsia and pregnancy-induced hypertension (PIH) following the clinical and/or laparoscopic diagnosis of endometriosis-associated infertility (case group; n = 245 ...
Desilva Tara M - - 2007
The major brain abnormality underlying cerebral palsy in premature infants is periventricular leukomalacia (PVL), a lesion of the immature cerebral white matter. Oligodendrocyte precursors (pre-OLs; O4(+)O1(-)) predominate in human cerebral white matter during the peak time frame for PVL (24-32 gestational weeks) and are vulnerable to excitotoxicity. We hypothesize that ...
Kim Shin Y - - 2007
OBJECTIVE: Pre-pregnancy obesity poses risks to both pregnant women and their infants. This study used a large population-based data source to examine trends, from 1993 through 2003, in the prevalence of pre-pregnancy obesity among women who delivered live infants. RESEARCH METHODS AND PROCEDURES: Data from the Pregnancy Risk Assessment Monitoring ...
Baumann Marc U - - 2007
Pre-eclampsia, a pregnancy-specific disorder, contributes substantially to perinatal morbidity and mortality of both, mother and newborn. An increasing number of biochemical agents were evaluated as markers for predicting pre-eclampsia. None of them has been proved to be of clinical value yet. Much effort has been put into assessing novel potential ...
Marchi Rita - - 2007
We have studied some biophysical properties of the fibrin network during the normal state of pregnancy and in patients with recurrent miscarriage (RM), in the first trimester of pregnancy. The fibrin polymerization process, followed by turbidity, showed that the rate of fibrin monomer assembly and the final turbidity was increased ...
Laury Angela - - 2007
Fresh pre- and postrigor pork sausage patties were manufactured in the Iowa State University Meat Laboratory and packaged either in modified atmosphere (MAP) with 0.4% carbon monoxide (CO) and 99.6% carbon dioxide (CO2) or on foam trays overwrapped with oxygen-permeable film (OW). Packages were stored at 2 to 40C under ...
Crocker I I Division of Human Development, The Medical School, University of Manchester, UK. - - 2007
Placental apoptosis is exaggerated in pre-eclampsia and cytotrophoblast proliferation is enhanced. This imbalance may be a primary pathogenic event, whereby excessive syncytiotrophoblast apoptosis counters cytotrophoblast fusion, promoting the liberation of syncytial material which perturbs the maternal vascular endothelium. We have previously shown that primary trophoblasts and explant cultured villous fragments ...
Malberg H - - 2007
Pre-eclampsia (PE) is a serious disorder with high morbidity and mortality occurring during pregnancy; 3%-5% of all pregnant women are affected. Early prediction is still insufficient in clinical practice. Although most pre-eclamptic patients show pathological uterine perfusion in the second trimester, this parameter has a positive predictive accuracy of only ...
Knox K S - - 2007
Pre-eclampsia affects 6-10% of pregnancies and is one of the primary causes of premature birth. It is widely accepted that inappropriate placental development, combined with environmental factors, plays a major role in disease pathogenesis. The p57(Kip2) mouse is the only mouse model of pre-eclampsia that recapitulates the full spectrum of ...
Crowley A - - 2007
BACKGROUND: The aim of this study was to quantify maternal plasma fetal DNA and total DNA in early pregnancy in intrauterine growth restriction (IUGR) or pre-eclampsia (PET). METHODS: A nested case control study was carried out in a University Teaching Hospital. Plasma samples were obtained from 1993 women before 20 ...
Jeyabalan Arundhathi - - 2007
An appreciation of the maternal physiologic adaptations that occur in the renal system during pregnancy is fundamental to the understanding and proper clinical management of normal pregnancy, renal disorders in the gravid patient, and pregnancy-specific conditions such as pre-eclampsia. In this article, the authors first address the anatomic changes that ...
Pearson D W M - - 2007
The relationships between markers of pregnancy planning and pre-pregnancy care and adverse outcomes (early pregnancy loss, major congenital anomaly and perinatal death) were examined in 423 singleton pregnancies in women with pre-gestational type I diabetes mellitus. Pregnancy planning and markers of pre-pregnancy care were associated with reduced risks of adverse ...
Matsuo Koji - - 2007
OBJECTIVE: To investigate the clinical features of hyperemesis gravidarum in Eastern Asian women. METHOD: Retrospective cohort study was conducted based on delivery records. Hyperemesis gravidarum was defined as a pregnancy with severe nausea and vomiting necessitating hospitalization with a body weight loss of over 5% from pre-pregnancy weight with ketonuria. ...
Kronborg Camilla S - - 2007
BACKGROUND: Alternatively activated macrophages expressing the CD163 and CD206 surface receptors are the dominant immune-cell type found in the placenta. The placental number and distribution of macrophages is altered in pre-eclampsia, and the generalised inflammatory reaction associated with pre-eclampsia might lead to shedding of soluble CD163 into the circulation. METHODS: ...
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