Search Results
Results 301 - 350 of 1758
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Gregoriou Odysseas - - 2008
OBJECTIVE: To compare the efficacy of letrozole to recombinant FSH for ovarian stimulation combined with IUI in a group of patients that had failed to conceive after clomiphene citrate (CC) and IUI. DESIGN: Prospective randomized trial with human subjects. SETTING: University-based fertility center. PATIENT(S): Fifty couples with unexplained infertility that ...
van Vliet Huib A A M - - 2008
INTRODUCTION: Activated protein C (APC) resistance is associated with an increased risk of venous thrombosis. High levels of estradiol and progesterone, e.g. during ovarian stimulation and pregnancy, as well as exogenously administered estrogens and progestagens during oral contraceptive use, induce an acquired form of APC resistance. Several coagulation factors display ...
Papaleo Enrico - - 2007
BACKGROUND: Polycystic ovary syndrome (PCOS) is often characterized by chronic oligo- or anovulation (usually manifested as oligo- or amenorrhea), and hyperandrogenism. In addition, 30-40% of PCOS women have impaired glucose tolerance, and a defect in the insulin signaling pathway (inositol-containing phosphoglycan mediators) seems to be implicated in the pathogenesis of ...
Quintero Rudolfo B - - 2007
OBJECTIVE: To compare pregnancy rates (PR) for letrozole and gonadotropins in individuals who failed to conceive with clomiphene citrate (CC). DESIGN: Retrospective cohort study. SETTING: University reproductive center. PATIENT(S): Individuals treated with letrozole or gonadotropins who failed to conceive with CC. INTERVENTION(S): Controlled ovarian hyperstimulation (COH), transvaginal ultrasound, ovulation induction, ...
Eskandar Mamdoh A - - 2007
OBJECTIVE: The purpose of the present study was to determine if the use of a gonadotropin-releasing hormone (GnRH) agonist can improve pregnancy and live-birth rates during superovulation and intrauterine insemination (IUI). SUBJECTS AND METHODS: In this prospective study, which started in January 2004 and finished in October 2006, women aged ...
van Weert Janne-Meije - - 2007
Patients' preferences for intrauterine insemination (IUI) relative to IVF were assessed using trade-off interviews, and the number of IUI cycles they would undergo before changing to IVF. A total of 73 couples undergoing IUI with a total of 111 interviews were included. Scenarios were offered where pregnancy chance after IUI ...
Erdem Mehmet - - 2008
OBJECTIVE: To determine the predictive value of basal antral follicle count (AFC) as a marker for pregnancy, live birth rate, and ovarian response in COH and intrauterine insemination (IUI) cycles in couples with unexplained subfertility. DESIGN: Prospective analysis. SETTING: University-based infertility clinic. PATIENT(S): One hundred forty-five women who were treated ...
Huirne J A - - 2007
We believe that appropriate comparison of optimal GnRH agonist and antagonist regimens has not been performed yet. Currently available meta-analyses included all comparative studies between GnRH agonists and antagonists performed so far, including less than optimal GnRH antagonist regimens. After critical appraisal of the various studied GnRH antagonist regimens in ...
Nargund G - - 2007
IVF is performed with oocytes collected in natural and stimulated cycles. Different approaches to ovarian stimulation have been employed worldwide. Following the introduction of GnRH antagonists and strategies to reduce multiple births such as single embryo transfer, there is a genuine scientific interest in the revival of natural cycle and ...
Zhang Heng - - 2007
Serine proteases and their cognate serpin-class inhibitors are involved in the controlled proteolytic events during follicular development, ovulation, formation, and maintenance of the corpus luteum (CL). In this study, we investigated the expression patterns of prostasin serine protease and protease nexin-1 (PN-1), a serine protease inhibitor also called serpin-E2, in ...
Nejad, Ensieh Shahrokh Tehrani
Background: Although the uterine fibroids are common, their influence on fertility remains controversial. The association of submucosal fibroid with subfertility is well recognized, but debate persists as to whether intramural fibroids can cause infertility and the evidence for its effect on pregnancy in cycles of assisted conception remains unclear. Objective: ...
Kaufmann Robert - - 2007
OBJECTIVE: To provide evidence of efficacy and safety for use of lutropin alfa in inducing follicular development and pregnancy in hypogonadotrophic hypogonadal women with profound gonadotrophin deficiency. DESIGN: An open-label, noncomparative extension of a randomized, double-blind, placebo-controlled study PATIENTS: A total of 31 hypogonadotrophic hypogonadal women with profound gonadotrophin deficiency ...
Detti Laura - - 2008
In this retrospective cohort study of 102 ovarian stimulation cycles for IVF/intracytoplasmic sperm injection using GnRH antagonist and gonadotropins, we sought to assess the effect of high E(2) levels on endometrial stripe thickness and its association with pregnancy outcomes and serum E(2) levels. We found no significant correlation between serum ...
Hompes Peter G A - - 2008
OBJECTIVE: To compare the effectiveness of highly purified hMG with recombinant FSH (rFSH) in IVF-intracytoplasmic sperm injection patients who were treated with a GnRH agonist. DESIGN: An open-label, prospective, randomized comparison of fixed gonadotropin regimens. SETTING: Eighteen Dutch IVF centers. PATIENT(S): Six hundred twenty-nine patients who were selected for IVF-intracytoplasmic ...
El-Toukhy Tarek - - 2008
OBJECTIVE: To examine the relationship between endometrial thickness and outcome of medicated frozen-thawed embryo replacement (FER) cycles. DESIGN: A retrospective observational study. SETTING: Assisted conception unit at a university hospital. PATIENT(S): All patients who underwent an FER cycle between 1997 and April 2006 and met the inclusion criteria. INTERVENTION(S): For ...
Gómez-Palomares Jose Luis - - 2008
To determine whether including a GnRH antagonist in controlled ovarian stimulation-intrauterine insemination cycles would increase pregnancy rates. Prospective randomized study. Private reproductive medicine clinic in Spain. Three hundred sixty-seven women with primary or secondary infertility. Patients were randomly assigned to controlled ovarian stimulation with recombinant FSH (75-150 IU/d) alone (controls, ...
Orvieto Raoul - - 2008
To evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in poor responders, we compared the stimulation characteristics of 21 cycles, which included the ultrashort gonadotropin-releasing hormone (GnRH) agonist combined with the flexible multidose GnRH antagonist, to the patients' previous failed in vitro fertilization attempts. The use of an ultrashort GnRH-agonist/GnRH-antagonist ...
Engmann Lawrence - - 2008
OBJECTIVE: To determine whether the use of luteal phase vaginal E(2) supplementation improves clinical pregnancy rates in patients undergoing IVF treatment. DESIGN: Prospective randomized controlled trial. SETTING: University-based tertiary fertility center. PATIENT(S): One hundred sixty-six patients undergoing their first cycle of IVF treatment. INTERVENTION(S): Patients underwent three different protocols for ...
Martin-Johnston Meredith - - 2007
The objective of this retrospective analysis was to compare the clinical outcomes of recombinant FSH (r-FSH) with combination r-FSH plus human menopausal gonadotrophin (HMG) protocols in a large private practice using a single IVF laboratory, from 2001 to 2003. Patients underwent ovarian stimulation by standard gonadotrophin-releasing hormone (GnRH) antagonist protocol ...
Lenton Elizabeth A - - 2007
Natural cycle IVF, without the use of LH down-regulation, is difficult because women start spontaneous LH surges at any time of the day and on any day of the week. This is not readily compatible with delivery of a routine IVF service and so historically the natural cycle has been ...
Moe William M - - 2007
Fluctuating pollutant concentrations pose challenges in the design and operation of air pollution control devices such as biofilters. Effective load equalization could decrease or eliminate many of these difficulties. In research described here, experiments were conducted to evaluate effects of cycle length and fraction of time contaminants are supplied on ...
Teramoto Shokichi - - 2007
Enclomiphene, an isomeric component of clomiphene citrate, acts antagonistically to the oestradiol receptor at the hypothalamus level, inhibiting both negative and positive feedback, and resulting in the induction of ovarian stimulation and suppression of ovulation. The minimal ovarian stimulation protocol takes full advantage of these characteristics of clomiphene citrate. Administration ...
Pacchiarotti Arianna - - 2007
To evaluate the efficacy of using both urinary and recombinant FSH in a combined protocol for ovarian stimulation in an IVF treatment program. A total of 119 infertile couples undergoing ICSI treatment were randomized prospectively in this study. After a standard down-regulation with GnRH analogue, the patients were randomized in ...
Elgindy Eman A - - 2008
OBJECTIVE: To measure serum anti-Müllerian hormone (AMH) during different phases of the menstrual cycle and to correlate the measurements with ovarian response and clinical-pregnancy rates in intracytoplasmic sperm injection cycles. DESIGN: Prospective cohort study. SETTING: University IVF unit. PATIENT(S): Thirty-three patients undergoing their first intracytoplasmic sperm injection treatment cycle with ...
Isikoglu Mete - - 2007
OBJECTIVE: To investigate the effect of continuous administration of gonadotropin-releasing hormone agonist (GnRHa) during the luteal phase in an intracytoplasmic sperm injection program. STUDY DESIGN: One hundred eighty-one women underwent a down-regulation protocol of GnRHa administered from the 21st day of the preceding cycle. Patients were randomized at initiation of ...
Killick Stephen R - - 2007
Ultrasound imaging can be used to assess the endometrium in a number of ways. In particular, time-lapse video recordings can show that the lining of the uterus undergoes rhythmical contractions that vary in strength and intensity throughout the ovarian cycle. These contractions appear to assist in sperm transport at the ...
Scarpa Bruno - - 2007
OBJECTIVE: To find optimal clinical rules that maximize the probability of conception while limiting the number of intercourse days required. DESIGN: Multicenter prospective study. Women were followed prospectively while they kept daily records of menstrual bleeding, intercourse, and mucus symptom characteristics. In some cycles, women sought to conceive, whereas in ...
Carrera-Rotllan J - - 2007
Prediction of IVF outcome on the first days of ovarian stimulation has focused clinical research for many years. The aim of this work is to predict the probability of pregnancy on the fourth day of ovarian stimulation for IVF cycle, using parameters usually determined in this stage--estradiol, antral follicle count--together ...
Casper Robert F - - 2009
Letrozole is at least as effective as clomiphene for inducing ovulation and achieving pregnancy in patients with polycystic ovarian syndrome. Potential advantages of letrozole include reduced multiple pregnancies, absence of antiestrogenic adverse effects, and the subsequent need for less intensive monitoring.
Pelinck M J - - 2007
BACKGROUND: In modified natural cycle IVF (MNV-IVF), treatment is aimed at using the one follicle that spontaneously develops to dominance, using a GnRH antagonist together with gonadotrophins in the late follicular phase only. METHODS: In this single-centre cohort study, nine cycles of MNV-IVF were offered to 268 patients. Cumulative pregnancy ...
Lee Jung Ryeol - - 2007
OBJECTIVE: To assess any detrimental effect of gonadotropin-releasing hormone (GnRH) antagonists on oocyte quality and embryo development by comparing the outcome of cryopreserved-thawed blastocyst transfers for cycles using a GnRH agonist or GnRH antagonist protocol for the controlled ovarian stimulation in the oocyte retrieval cycle. DESIGN: Retrospective comparative study. SETTING: ...
Ubaldi F - - 2007
Over the last two decades, easier and less expensive stimulation treatments have been largely replaced by more complex and more demanding protocols. Since the mid-nineties, long-term gonadotrophin-releasing hormone agonist stimulation protocols have been widely used. Such lengthy expensive regimens are not free from short- and long-term risks and complications. Mild ...
Moon Shin Yong - - 2007
AIM: To compare the efficacy and safety of a new recombinant human follicle-stimulating hormone (FSH; DA-3801) with follitropin-alpha (Gonal-F) in women undergoing controlled ovarian hyperstimulation (COH) for assisted reproductive technology (ART). METHODS: This was a phase III, multicenter, randomized, non-inferiority study. A total of 97 women were randomized to receive ...
Kafy Souzan - - 2007
PURPOSE OF REVIEW: To review recent advances in ovulation induction. RECENT FINDINGS: Aromatase inhibitors can replace clomiphene citrate as ovulation-inducing substances. The most widely used aromatase inhibitor for this purpose is letrozole and the optimal dose is 5 mg daily for 5 days. Compared to clomiphene citrate, it is associated ...
Vyjayanthi S - - 2007
Patients with anovulatory infertility, who received treatment at one unit over a four year period, were assessed to determine the pregnancy rate and the incidence of complications while undergoing ovulation induction with gonadotropins. The patients in this group who had further in vitro fertilization (IVF) treatment were followed up, and ...
Gera Puja S - - 2008
OBJECTIVE: To determine the role of saline infusion sonography (SIS) in uterine evaluation before a frozen embryo transfer (FET) cycle. DESIGN: Retrospective cohort analysis. SETTING: University hospital. PATIENT(S): Thirty-six patients who had uterine evaluation by SIS before FET cycle. INTERVENTION(S): The SIS was performed in the follicular phase of the ...
Orvieto Raoul - - 2007
In a study on the influence of methotrexate (MTX) treatment on ovarian stimulation characteristics during the subsequent IVF cycle, 14 patients admitted to our department with the diagnosis of ectopic pregnancy and successfully treated with MTX were evaluated. No differences were observed in ovarian stimulation characteristics between the IVF cycle ...
Sneeringer Rita - - 2008
OBJECTIVE: To determine if there is an association between first IVF cycle outcome and subsequent delivery rate for women over 40 years. DESIGN: Retrospective data analysis. SETTING: Large, private academically affiliated IVF center. INTERVENTION(S): Patients over 40 years of age undergoing IVF. MAIN OUTCOME MEASURE(S): Delivery rate compared between patients ...
Fumuso Elida Ana - - 2007
Our objective was to characterize immune parameters in susceptible (SM) and resistant (RM) mares, with and without artificial insemination (AI) and immunomodulation. Eight RM and eight SM were selected based on their reproductive history and functional tests. Both groups of mares were evaluated during three consecutive cycles: Cycle 1, untreated ...
Al-Inany H G - - 2007
Gonadotrophin-releasing hormone (GnRH) antagonists suppress gonadotrophin secretion resulting in dramatic reduction in treatment cycle duration. Assuming comparable clinical outcomes, these benefits may justify changing the standard long GnRH agonist protocol to GnRH antagonist regimens. To evaluate the evidence, databases (e.g. Cochrane Library, MEDLINE, EMBASE) were electronically searched, hand searches were ...
Greco E - - 2007
Italian legislation regarding reproductive medicine limits the number of embryos transferred per attempt to three. Thus, in order to achieve pregnancy, more IVF cycles may be required, generating a need for methods of ovarian stimulation with fewer side effects. The gonadotrophin-releasing hormone (GnRH) antagonists have several advantages in this respect, ...
Moini Ashraf - - 2007
OBJECTIVE: To determine the effect of low-dose aspirin on ovarian response, implantation and pregnancy rates in patients undergoing in-vitro fertilization (IVF) cycles. METHODS: We performed a randomized analysis of 145 infertile women with a mean+/-SD age of 29.6 +/- 4.47 years who underwent cycles of IVF. Patients received 100 mg ...
Lim Jin-Ho - - 2007
Natural cycle IVF produced the world first successful live birth, but slowly this treatment has been replaced by ovarian stimulated cycle IVF, because it has been believed ovarian stimulated cycle IVF will increase the number of available embryos for transfer. Therefore, it directly increases the chance of pregnancy from the ...
Kadoch Isaac Jacques - - 2007
The objective of this retrospective analysis is to evaluate whether patients developing a dominant follicle in an in-vitro maturation (IVM) programme can be included in a natural cycle IVF (nIVF) programme. In a university teaching hospital, a total of 38 patients with polycystic ovarian syndrome were treated by metformin before ...
Engmann Lawrence - - 2008
OBJECTIVE: To determine whether there are any differences in the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rates in high-risk patients undergoing IVF using a protocol consisting of GnRH agonist trigger after cotreatment with GnRH antagonist or hCG trigger after dual pituitary suppression protocol. DESIGN: Prospective randomized controlled trial. ...
Griesinger Georg - - 2007
OBJECTIVE: To report the outcome of frozen-thawed embryo replacement cycles after GnRH-agonist triggering of final oocyte maturation in the collecting cycle with GnRH-antagonist. DESIGN: Prospective, observational, multicentric clinical study. SETTING: Tertiary university-affiliated IVF centers. PATIENT(S): Patients under observation previously had been recruited into two concurrently performed, independent, randomized controlled trials ...
Cantineau Astrid E P - - 2007
OBJECTIVE: To reveal the prevalence of premature LH surges in an IUI program. Furthermore, to investigate whether these LH surges influence treatment outcome and whether the prevalence of LH surges differs between cycles stimulated with clomiphene citrate (CC) and cycles stimulated with recombinant follicle-stimulating hormone (rFSH). DESIGN: Prospective cohort study. ...
Kolibianakis Efstratios M - - 2007
OBJECTIVE: To evaluate the effect of different human chorionic gonadotropin (hCG) doses on the ongoing pregnancy rates in patients with polycystic ovary syndrome (PCOS). DESIGN: Prospective, randomized, controlled trial. SETTING: Tertiary university referral center. PATIENT(S): Eighty PCOS patients. INTERVENTION(S): Patients were randomized to receive 10,000 IU (n = 28), 5000 ...
Esmailzadeh Seddigheh - - 2007
OBJECTIVES: To investigate whether endometrial thickness on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. DESIGN: A retrospective study. PATIENT(S): Two hundred forty-nine women undergoing IUI cycles. SETTING: University hospital-based infertility center. INTERVENTION(S): Endometrial thickness on the day of hCG administration, cycle parameters, and sperm ...
Sakhel Khaled - - 2007
To compare the in vivo effectiveness of recombinant (r) hCG with urinary (u) hCG during controlled ovarian hyperstimulation and intrauterine insemination (COH-IUI) cycles. Prospective controlled clinical study. Private IVF center. Two hundred eighty-four subjects undergoing COH-IUI cycles. Women were randomized into receiving r-hCG or u-hCG for final maturation and induction ...
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