Search Results
Results 201 - 250 of 1758
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Rabinson Jacob - - 2009
To examine pregnancy rate in patients undergoing controlled ovarian hyperstimulation (COH) with use of multidose GnRH antagonists in multiple repeated IVF cycle attempts, we conducted a survey in 785 consecutive IVF cycles in our unit. Although pregnancy rate significantly decreased beyond the second IVF cycle attempt, no significant decrease was ...
Orvieto Raoul - - 2009
In an attempt to examine and compare the effect of the two commercially available recombinant FSH on ovarian stimulation characteristics and IVF cycle outcome, we studied 264 IVF cycles in patients with a favorable prognosis a priori, 198 in patients using follitropin-alpha, and 68 in patients using follitropin-beta. Although both ...
Hayden Catherine - - 2008
The ability to prevent an endogenous LH surge revolutionised the efficacy of assisted reproductive techniques (ART) such that GnRH agonists were rapidly adopted in the 1980s. Prior to this, premature luteinisation occurred in up to 25% of superovulated cycles leading to cycle cancellation and severely compromised outcomes. Analogues have been ...
Pearson Kimberly R - - 2009
Among 2,245 women, those who experienced a chemical pregnancy that failed to progress to a clinically recognized pregnancy or a spontaneous abortion on their first IVF cycle were more likely to discontinue IVF treatment than those whose first cycle ended before embryo transfer or who did not have a positive ...
Requena Antonio - - 2008
Letrozole is the third-generation aromatase inhibitor (AI) most widely used in assisted reproduction. AIs induce ovulation by inhibiting estrogen production; the consequent hypoestrogenic state increases GnRH release and pituitary follicle-stimulating hormone (FSH) synthesis. A systematic search of the literature was performed for both prospective and retrospective studies. Meta-analyses of randomized ...
Schimberni Mauro - - 2009
OBJECTIVE: To determine the role of the natural cycle for in vitro fertilization (IVF) in poor responder patients. DESIGN: Retrospective survey. SETTING: Private center for assisted reproduction. PATIENT(S): 294 women who were poor responders in a previous IVF cycle. INTERVENTION(S): Analysis of 500 consecutive natural cycles IVF. MAIN OUTCOME MEASURE(S): ...
Bozdag Gurkan - - 2008
Recurrent implantation failure (RlF) may be due to unrecognized uterine pathology. Hysterosalpingography, transvaginal ultrasonography, saline infusion sonography and hysteroscopy are the tools to assess the inner architecture of the uterus. Hysteroscopy is considered to be the gold standard; however, the validity of hysteroscopy may be limited in the diagnosis of ...
Dmitrovic Romana - - 2008
To detect the endometrial volume change in conception cycles. Additionally we measured endometrium in three planes, to see if the hypothesized endometrial volume differences will be detectable by this surrogate technique. Following the embryo transfer, a three-dimensional ultrasound exam was performed on average days 22 and 28 of the cycle. ...
Takasaki Akihisa - - 2008
OBJECTIVE: To evaluate the benefit of colony-stimulating factor-1 (CSF-1) adjuvant therapy to poor responders during a controlled ovarian hyperstimulation (COH) cycle. DESIGN: Prospective clinical study. SETTING: University hospital, general hospital, and private IVF clinic in Japan. PATIENT(S): Thirty normogonadotropic patients who did not respond to conventional COH protocols. INTERVENTION(S): Eight ...
Lai Tsung-Hsuan - - 2009
OBJECTIVE: To evaluate the relationship between serum P:E(2) ratio on the day of hCG administration and the clinical outcomes in infertile women with normal ovarian reserve treated with a long GnRH agonist (GnRH-a) protocol. DESIGN: Retrospective analysis of IVF-embryo transfer data. SETTING: University teaching hospital. PATIENT(S): One hundred thirty-nine infertile ...
Erdem Ahmet - - 2009
OBJECTIVE: To determine the impact of luteal phase support on pregnancy rates in ovarian stimulation and intrauterine insemination (IUI) cycles with gonadotropins in couples with unexplained infertility. DESIGN: Prospective randomized controlled trial. SETTING: University-based infertility clinic. PATIENT(S): Two hundred fourteen couples with unexplained infertility who were treated during 427 ovarian ...
Haydardedeoglu Bulent - - 2009
OBJECTIVE: To determine whether conversion of high-response gonadotropin/intrauterine insemination (IUI) cycles to "rescue" in vitro fertilization (IVF) yields a higher implantation and pregnancy rate as found in matched IVF controls. DESIGN: A prospective study with a retrospective controlled section. SETTING: Baskent University Department of Obstetrics and Gynecology. PATIENT(S): Thirty-two patients ...
Badawy Ahmed - - 2009
OBJECTIVE: To compare clomiphene citrate (CC) and letrozole used for superovulation before intrauterine insemination (IUI) in unexplained infertility. DESIGN: Prospective randomized trial. SETTING: A university teaching hospital and a private practice setting. PATIENT(S): Four hundred and twelve infertile women with unexplained infertility. INTERVENTION(S): Patients were randomized to treatment with 100 ...
De Muro Pierina - - 2009
OBJECTIVE: To evaluate transforming growth factor beta1 (TGF-beta1) and glycosaminoglycans (GAG) changes in human plasma and urine during the menstrual cycle, IVF-ET, and pregnancy. DESIGN: Prospective clinical study. SETTING: University hospital. PATIENT(S): Thirteen women with apparently normal menstrual cycle (group 1); 18 women undergoing IVF-ET (group 2); and 14 low-risk ...
Jungheim Emily S ES Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Washington University in Saint Louis, Saint Louis, MO 63108, USA. - - 2009
To determine whether morbid obesity is associated with decreased pregnancy and live birth rates after IVF in women with polycystic ovary syndrome (PCOS). Retrospective cohort study. University-based fertility center. Seventy-two women with PCOS who completed their first IVF cycle between 2001 and 2006. Outcomes of IVF were compared between women ...
van Rumste M M E - - 2008
BACKGROUND: The influence of multifollicular growth on pregnancy rates in subfertile couples undergoing intrauterine insemination (IUI) with controlled ovarian hyperstimulation (COH) remained unclear. METHODS: Relevant papers were identified by searching MEDLINE, EMBASE and the Cochrane Library. A meta-analysis was performed and Mantel-Haenszel pooled odd ratios (ORs) and risk differences with ...
Yarali Hakan - - 2009
To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). Retrospective, case-control study. Anatolia Women and IVF Center. Eight hundred eighty-five consecutive patients (1383 cycles) predicted to have or with a history of ...
Taberner E - - 2008
The Catalonian donkey breed is in danger of extinction, and much needs to be learned about the reproductive features of its females if breeding and conservation programmes are to be successful. This study reports the oestrous behaviour, oestrus cycle characteristics and dynamic ovarian events witnessed during 50 oestrous cycles (involving ...
Weitzman Vanessa N - - 2009
OBJECTIVE: To compare IVF outcomes in poor-responder patients undergoing stimulation after luteal phase E(2) patch/GnRH antagonist (LPG) protocol versus microdose GnRH agonist protocol. DESIGN: Retrospective analysis. SETTING: University-based IVF center. PATIENT(S): Forty-five women undergoing ovarian stimulation for IVF using the LPG protocol were compared with 76 women stimulated with the ...
Orvieto Raoul - - 2009
To evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in patients with repeated IVF failures and poor embryo quality we compared the stimulation characteristics of ten cycles which included ultrashort flare GnRH agonist combined with flexible multidose GnRH antagonist with the patients' earlier failed IVF attempts. The use of ultrashort ...
Platteau Peter - - 2008
The objective of this study was to compare the live birth rates resulting from ovarian stimulation with highly purified human menopausal gonadotrophin (HP-HMG), which combines FSH and human chorionic gonadotrophin-driven LH activities, or recombinant FSH (rFSH) alone in women undergoing IVF cycles. An integrated analysis was performed of the raw ...
Cheon Kang Woo - - 2008
This study was aimed to evaluate the efficacy of a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) as compared with daily administrations of short-acting GnRHa in controlled ovarian hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) cycles. The mean dosage of recombinant follicle-stimulating hormone (rFSH) required for ...
Erdem Ahmet - - 2008
The objective of this cross-sectional study was to identify the prognostic factors that influence the outcome of ovarian stimulation with intrauterine insemination (IUI) cycles using gonadotrophins in couples with unexplained and mild male-factor subfertility. A total of 838 cycles in 456 women with unexplained and mild male-factor subfertility attending a ...
Kurzawa Rafal - - 2008
Embryological and clinical efficacy of gonadotropin-releasing hormone (GnRH) antagonist and agonist stimulation protocols in non-obese women with polycystic ovarian syndrome (PCOS) were compared. A prospective randomized study. Setting: Medical University Hospital. Patients: 70 infertile PCOS patients; 33 in GnRH antagonist and 37 in GnRH agonist group. Similar mature metaphase II ...
Snaifer Elie - - 2008
To report a case of empty follicle syndrome (EFS) after human error occurring in hCG administration and discuss the specific management of this event in a GnRH antagonist cycle. Case report. A university hospital. A 27-year-old woman admitted for a first oocyte retrieval resulting in empty follicle syndrome. The cause ...
Goossens V - - 2008
The eighth report of the European Society of Human Reproduction and Embryology PGD Consortium is presented documenting cycles collected for the calendar year 2005 and follow-up of the pregnancies and babies born until October 2006 which resulted from these cycles. For the first time, the delivery rates for each indication ...
Baruah Jinee - - 2009
OBJECTIVES: To compare the effects of letrozole and clomiphene citrate (CC) on endometrial response in PCOS using subendometrial spiral artery Doppler. METHODS: Fifty consecutive patients of anovulatory PCOS were recruited. Twenty-five patients (58 cycles) received 2.5-5 mg of letrozole; 25 patients (56 cycles) received 50-100 mg of CC (both orally ...
Phillips Rebecca Sellin - - 2008
The objective of this study was to determine if sexual swellings in mandrills (Mandrillus sphinx) are a reflection of reproductive endocrine state. Urine samples were assayed using an enzyme immunoassay measuring pregnanediol-3-glucuronide (PdG) and estrone conjugates (E(1)C). Hormone patterns of ovarian cycles, pregnancy and lactation were characterized and compared with ...
Wang Chia-Woei - - 2008
Tamoxifen has been reported to be oestrogenic on the lower genital tract. To evaluate its potential positive effect on the endometrium, and consequently early miscarriage and ongoing pregnancy rate, a prospective study was employed in patients for intrauterine insemination who failed to develop an adequate endometrial thickness in a previous ...
Randolph John F JF - - 2008
INTRODUCTION: The relationship between reproductive physiology and reproductive behavior, a central theme in Professor Lorraine Dennerstein's career, is complex but presumably serves to optimize human reproduction. AIM: To review the endocrinology of the reproductive years and significant work by Professor Dennerstein relating that endocrinology with reproductive behavior. METHODS/MAIN OUTCOME MEASURES: ...
Rajashekar Lavanya - - 2008
Polycystic ovary syndrome (PCOS) is one of the most common (15-20%) endocrine disorders in women of childbearing age. Although it is a major cause of infertility, its etiology remains unknown and its treatment difficult. To evaluate the incidence, treatment and outcome of patients with PCOS. Retrospective analysis. PCOS patients (914 ...
Bosch E - - 2008
BACKGROUND: Highly purified hMG (hp-hMG) has recently shown better cycle outcome than the recombinant FSH (rFSH) when compared in GnRH agonist long protocol cycles. However, they have not yet been compared in GnRH antagonist cycles. METHODS: A RCT comparing the ongoing pregnancy rate (primary end-point) in 280 patients undergoing IVF/ICSI ...
Haadsma M L - - 2008
BACKGROUND: The predictive value of ovarian reserve tests (ORTs) for spontaneous pregnancy is unclear. Our study aimed to determine whether ORTs have added value to previously identified prognostic factors for spontaneous pregnancy in subfertile ovulatory couples. METHODS: A prospective cohort study was performed on 474 subfertile ovulatory couples in two ...
Verhagen T E M - - 2008
BACKGROUND: Dropouts in IVF-programmes affect cumulative pregnancy rates (CPRs), but it is unknown what the impact of loss to follow-up is. METHODS: Data were obtained from 588 couples starting IVF treatment ('as treated group'). Cycle-based and real-time-based CPRs were calculated using three assumptions for dropouts: dropouts having no probability of ...
Senturk Levent M - - 2008
PURPOSE OF REVIEW: To review the etiology, diagnosis and clinical importance of thin endometrium during assisted reproductive technology cycles and to find out better ways to deal with it. RECENT FINDINGS: Precise and specific endometrial maturational development is crucial in allowing implantation following assisted reproduction. As endometrial biopsy is invasive ...
Wang Lina - - 2008
OBJECTIVE: To determine the effect of luteinized unruptured follicle (LUF) cycles on frozen thawed embryo transfer (FET). DESIGN: A retrospective analysis comparing the clinical outcomes after FET among 144 cases of luteinized unruptured follicle (LUF) cycles and 866 cases of ovulation cycles. SETTING: Reproductive medical center, Beijing China. PATIENTS: Chinese ...
Rashid M R Zainul - - 2008
The long agonistic protocol for controlled ovarian hyperstimulation (COH) is effective and used most often, thus is considered the gold standard. Therefore any new regimen has to be compared in its results with those obtained with the long protocol. This report compares the efficacy of GnRH agonist and antagonist in ...
Horikawa Takashi - - 2008
To evaluate the cystectomy-induced damage on the follicular growth and ovulation of an affected ovary during natural cycles. Twenty-eight infertile patients with unilateral ovarian endometriomas who underwent laparoscopic cystectomy were retrospectively evaluated. The ovulation rate of an affected ovary during natural cycles was compared before and after cystectomy in each ...
Pelinck M J - - 2008
In modified natural cycle IVF (MNC-IVF), treatment is aimed at using the one follicle that spontaneously develops to dominance, using a GnRH-antagonist together with gonadotrophins in the late follicular phase only. The MNC-IVF is of interest because of its low-risk and patient-friendly profile. The effect of application of MNC-IVF preceding ...
Homburg Roy - - 2009
To examine whether and when conception may be achieved in multiple repeated in vitro fertilization cycles, we surveyed the outcome of 2760 consecutive cycles in our unit. The pregnancy rate statistically significantly decreased after the third cycle attempt, but no statistically significant decrease was observed between cycles 4 and 20; ...
Nakayama Masato - - 2008
Gonadotropin-releasing hormone agonist (GnRH-a) therapy is frequently applied to reduce the volume of uterine leiomyomas (UL). In addition, the possible relationship between mast cells (MC) within UL and the development of UL has been suggested, but the role of MC in UL remains to be determined. UL with or without ...
Pal Lubna - - 2008
To determine if attempts to maximize oocyte yield during ovarian stimulation translates into improved outcome of in vitro fertilization (IVF) cycles. Retrospective study. Academic tertiary care IVF center. 806 de-identified nondonor IVF cycles. Evaluation of fresh nondonor IVF cycles (n = 806) for the period January 1, 1999, to December ...
Moon Hwa Sook - - 2008
OBJECTIVE: To evaluate the effect of short coasting, by withdrawing both gonadotropins and gonadotropin-releasing hormone (GnRH) agonist, on the prevention of severe ovarian hyperstimulation syndrome (OHSS) without compromising pregnancy outcome. DESIGN: Retrospective study. SETTING: Large urban medical center. PATIENT(S): Forty-four women who had been coasted during controlled ovarian hyperstimulation (COH) ...
Cole Laurence A - - 2009
OBJECTIVE: To address conflicts in the normal variabilities of the menstrual cycle using the newest generation test methods and to establish normal ranges for use in clinical practice. DESIGN: Daily urine samples were collected from 167 women eager to achieve pregnancy. Samples were tested prospectively for LH and total hCG. ...
Sullivan Elizabeth - - 2008
BACKGROUND: The aim of this study was to calculate assisted reproductive technology (ART) success rates for fresh autologous and donor cycles in women aged > or = 45 and the resultant cost per live birth. METHODS: We performed a retrospective population-based study of 2339 ART cycles conducted in Australia, 2002-2004 ...
Lainas Trifon G - - 2008
BACKGROUND: Although initial studies in poor responders using GnRH antagonists have reported encouraging results, they are limited in number, only a few of them are prospective, while the majority is characterized by limited power to detect a clinically important difference. METHODS: A randomized controlled trial was performed in patients with ...
Homburg Roy - - 2009
The failure of tests of ovarian reserve to predict clinical pregnancy in women 40 years old and older prompted this study of the predictive value of information obtained during the first cycle of in vitro fertilization (IVF). Stimulation characteristics during the first IVF cycle attempt were unhelpful in predicting the ...
Matsuura Toshiki - - 2008
Although many reports support stimulated in vitro fertilization, several patients do not respond to it well. Furthermore, stimulated treatment could be associated with reduced ovarian response. We describe three successful cases involving patients of advanced age from whom dominant follicles were retrieved during the natural cycle. All patients had failed ...
Lim Jin-Ho - - 2009
To determine a successful method of selecting patients for natural cycle IVF combined with in vitro maturation (IVM) of immature oocytes and to determine treatment efficacy. Retrospective analysis of IVF treatments. Hospital IVF clinic. Women with infertility according to ovarian reserve and endocrine profile were selected for different treatments. According ...
Baker Valerie L - - 2009
OBJECTIVE: To compare the efficacy of highly purified human urinary follicle stimulating hormone (HP-hFSH) versus human recombinant follitropin-alpha (rFSH) in volunteers undergoing controlled ovarian stimulation for IVF. DESIGN: A randomized, controlled, investigator-blind trial. SETTING: Four assisted reproductive technology centers. PATIENT(S): One hundred fifty-two IVF patients. INTERVENTION(S): Volunteers, aged 18-39, were ...
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