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Nejad Ensieh Shahrokh Tehrani - - 2011
This study is designed to compare the results of in vitro fertilisation (IVF) in polycystic ovary syndrome (PCOS) and tubal factor disorders. This was a cohort study performed in Royan Institute from 2007 to 2009. For this evaluation, 183 patients with PCOS and 183 patients with tubal factor (control group), ...
Cheng J - - 2010
This pilot study evaluated the effects of coadministration of metformin with clomiphene citrate (CC) and human menopausal gonadotrophin (HMG) in women with CC-resistant polycystic ovary syndrome (PCOS). Sixty women with PCOS were randomly assigned to receive 3 months' treatment with metformin or placebo together with CC and HMG. Transvaginal ultrasound ...
Farhi Jacob - - 2010
OBJECTIVE: To examine leading follicle size on human chorionic gonadotropin (hCG) day and pregnancy rate in anovulatory polycystic ovary syndrome (PCOS) patients treated with clomiphene citrate (CC). DESIGN: Retrospective cohort study. SETTING: Fertility clinics in women's health centers. PATIENTS: Data on 291 infertile women with PCOS and irregular cycles who ...
Devesa Marta - - 2010
OBJECTIVE: To determine the efficacy of the flare-up agonist and the antagonist protocols in patients with poor prognosis for ovarian response. METHODS: A randomised trial was conducted on two hundred and twenty-one women considered as having poor prognosis for ovarian response to stimulation, based on previous cycles or clinical criteria. ...
Asimakopoulos Byron - - 2010
The aim of this study was to measure circulating and intrafollicular concentrations of three inflammatory cytokines from women undergoing ovarian stimulation in order to determine their prognostic value in the outcome of intracytoplasmic sperm injection/embryo transfer cycles. MATERIALS AND METHODS: A total of 72 women following ovarian stimulation and intracytoplasmic ...
Abu Hashim Hatem - - 2010
To compare the effect of letrozole with laparoscopic ovarian diathermy (LOD) for ovulation induction in clomiphene citrate (CC) resistant women with polycystic ovary syndrome (PCOS). Two hundred and sixty anovulatory women with CC-resistant PCOS were selected in this randomized controlled trial. Group A (n = 128) received 2.5 mg letrozole daily for 5 days ...
Abu Hashim Hatem - - 2011
Aim.?To compare the effect of combined metformin?clomiphene citrate (CC) with highly purified urinary FSH (HP-uFSH) for ovulation induction in CC-resistant women with polycystic ovary syndrome (PCOS). Methods.?One-hundred fifty-three anovulatory women with CC-resistant PCOS were selected in this randomised controlled trial. Patients received combined metformin?CC (n?=?75, 205 cycles) or HP-uFSH (n?=?78, ...
Nicopoullos James D M - - 2011
To determine optimal management with one or two mature follicles after stimulation. Retrospective analysis. Lister fertility clinic. A total of 1,350 IVF/intracytoplasmic sperm injection cycles (7.3% of total) during 1998-2009 were found to have one or two mature follicles. Group 1 (n = 807) comprised those who proceeded to vaginal ...
Kupka Markus S - - 2011
To our knowledge, this is the first analysis in which male and female weights have been combined. The registry dataset covering a 12-year period was analysed for all treatment cycles where an embryo transfer was reported. In all, 706,360 cycles were analysed. Treatments include IVF, ICSI, IVF/ICSI and CPE. The ...
Yoldemir Tevfik - - 2011
Aim. To determine if endometrial trauma during embryo transfer trials (ETTs) improves implantation and clinical pregnancy rates in intracytoplasmic sperm injection treatment cycles. Patients. One-hundred fifty women undergoing their first IVF treatment were included in a prospective randomised study in a University hospital clinic. ETTs were performed either on day 21 of ...
Bentov Yaakov - - 2010
OBJECTIVE: To report an ongoing pregnancy after in vitro fertilization (IVF) with ovarian stimulation using a gonadotropin-releasing hormone (GnRH) antagonist that resulted in two waves of follicular growth. DESIGN: Case report. SETTING: University of Toronto affiliated infertility clinic. PATIENT(S): A 33-year-old woman with a 3-year history of secondary infertility. INTERVENTION(S): ...
Chambers Georgina M - - 2010
To compare a strategy of two cycles of intrauterine insemination with controlled ovarian hyperstimulation (IUI/COH) vs one in vitro fertilisation (IVF) treatment programme (one fresh plus associated frozen embryo cycles) in couples presenting with unexplained, mild male or mild female subfertility. A retrospective cohort design was used and analysed according ...
Hosseini Marzieh Agha - - 2010
Gonadotropin-releasing hormone (GnRH) antagonists have reduced the incidence of severe ovarian hyper stimulation syndrome (OHSS) and rate of hospitalization due to severe OHSS, especially in polycystic ovarian syndrome (PCOS) patients. The present study aimed to compare the outcomes of patients with PCOS undergoing controlled ovarian hyperstimulation (COH) with GnRH agonist ...
Yanushpolsky Elena - - 2011
To compare patterns of luteal phase bleeding (LPB) in IVF cycles supplemented with Crinone and with intramuscular progesterone (IMP) and to evaluate the impact of luteal estrogen supplementation on LPB. Prospective, randomized trial and post hoc analysis. University-affiliated IVF unit. Women under age 40 with day 3 FSH <15 mIU/mL ...
Jukic Anne Marie Z - - 2010
Previous studies of hormone patterns after clinical miscarriage suggest reduced pituitary function. Hormonal effects of very early pregnancy loss (before 6 weeks gestation) have not been described. We used within-woman differences between menstrual cycles in urinary hormone measurements from women in the North Carolina Early Pregnancy Study to describe hormonal ...
Freour Thomas - - 2010
The purpose of this study was to evaluate the significance of converting an IVF stimulation cycle with poor ovarian response to an IUI cycle. Between January and December 2007, 47 cycles of IVF conversion to IUI were retrospectively studied in 44 infertile women who had a low response to ovarian ...
Baran Safak - - 2010
To compare the efficacy of metformin and clomiphene citrate (CC) therapies for ovulation induction in anovulatory infertile women with polycystic ovary syndrome (PCOS). A total of 69 consecutive infertile, anovulatory women with PCOS were enrolled in this prospective, non-randomized trial. The women were prescribed either 1,700 mg/day metformin or CC ...
Kini Suresh - - 2010
To evaluate the role of Anti-mullerian hormone (AMH) in predicting cumulative pregnancy outcome during in-vitro fertilization (IVF) treatment. Serum AMH levels on day 6 of ovarian stimulation were taken from 180 women undergoing IVF with or without intracytoplasmic sperm injection (ICSI). The main outcome measures were ongoing pregnancy in the ...
Vrontikis Alaina - - 2010
Antral follicle count (AFC) is used as a marker of ovarian response. We assessed its value in predicting pregnancy outcomes in ovum donation cycles by retrospective review. Oocyte donors (n = 94) underwent ovarian hyperstimulation using rFSH and GnRH-antagonists. Recipients were synchronized using GnRH-agonist down-regulation followed by fixed dose of ...
Vause Tannys D R - - 2010
To review current non-pharmacologic and pharmacologic options for ovulation induction in women with polycystic ovary syndrome (PCOS). This guideline reviews the evidence for the various options for ovulation induction in PCOS. Ovulation, pregnancy and live birth rates, risks, and side effects are the outcomes of interest. Published literature was retrieved ...
Cho Suhyun - - 2010
Female patients with atopic dermatitis (AD) often experience cutaneous deterioration associated with their pregnancy or menstrual cycle. We wanted to determine the prevalence of symptom aggravation as related to pregnancy and the menstrual cycle in female patients with AD. One hundred female patients with AD were included in the study ...
Johnson N P - - 2010
Ovulation induction treatment with metformin, either alone or in combination with clomiphene citrate (CC), remains controversial even though previous randomized trials have examined this. A double blinded multi-centre randomized trial was undertaken including 171 women with anovulatory or oligo-ovulatory polycystic ovary syndrome. Women with high body mass index (BMI) > ...
Bonduelle Maryse - - 2010
BACKGROUND: A concern for new compounds in fertility treatment is the possible risk of perinatal complications or birth defects. To demonstrate long-term safety of ganirelix (GnRH antagonist) treatment in controlled ovarian stimulation (COS), follow-up data on pregnancy and neonatal outcome were analysed for 1000 fetuses (>or=16 gestational weeks). METHODS: Obstetrical ...
Yovich John L - - 2010
In a sequential crossover study of IVF conducted from 2002 to 2006, growth hormone (GH) supplementation was assessed in poor-prognosis patients, categorized on the basis of past failure to conceive (mean 3.05 cycles) due to low response to high-dose stimulation (<3 metaphase II oocytes) or poor-quality embryos. Pregnancy rates in ...
Raffone Emanuela - - 2010
OBJECTIVE: The aim of this study was to compare the effectiveness of myo-inositol (MYO) and metformin, in monotherapy or in association with recombinant follicle stimulating hormone (r-FSH), in the treatment of menstrual irregularities, chronic anovulation, and female infertility in patients with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS: One hundred ...
Vlaisavljevi? Veljko - - 2010
BACKGROUND: The development of new fertility treatment options has facilitated individualized assisted reproductive technology (ART) protocols to improve outcomes. Manufacturing improvements to recombinant human follitropin alfa have allowed precise dosing based on mass (filled-by-mass; FbM) rather than bioactivity (filled-by-bioassay; FbIU). Continued monitoring and reporting of follitropin alfa treatment outcomes in ...
Jinno Masao - - 2010
OBJECTIVE: Insulin resistance is associated with aging and stress, both common among patients repeatedly failing to conceive with in vitro fertilization (IVF repeaters). In the present study we examined whether low-dose metformin could improve the outcome in IVF repeaters without polycystic ovary syndrome (PCOS). DESIGN: Study I was a preliminary ...
Mann Jessica S - - 2010
Patients undergoing first IVF cycle using MDL from October 2005 to November 2008 had serum FSH, LH, and estradiol (E2) levels measured prior to and 2 days after initiation of MDL; and evidence of a follicular flare, defined as a doubling in endogenous gonadotropins, was evaluated and correlated with clinical ...
Jerzak MaƂgorzata - - 2010
PROBLEM: Does addition of enoxaparin to sildenafil and etanercept immunotherapy improve IVF outcome? METHODS: Report of a striking case with 15 IVF failures. RESULT: When enoxaparin was added, the 16th IVF cycle generated a healthy male baby. CONCLUSIONS: Combination therapy that includes a heparin may allow successful IVF outcome and ...
Al-Inany Hesham - - 2010
To study the effectiveness of clomiphene citrate (CC) in preventing a premature LH surge during controlled ovarian stimulation in women undergoing assisted reproduction. Prospective, randomized, controlled trial. University hospital. Two-hundred thirty couples with mild male factor, or unexplained infertility. Couples were randomized to receive human menopausal gonadotrophins (hMG) followed by ...
Kyrou Dimitra - - 2010
OBJECTIVE: The purpose of this study is to assess the effect of luteal phase supplementation (LPS) on pregnancy rates in human chorionic gonadotropin (hCG)-induced natural frozen-thawed (FET) cycles. STUDY DESIGN: All performed hCG-induced natural FET cycles from January 2006 until August 2007 were retrospectively identified. The study group consisted of ...
Elgindy Eman A - - 2010
This randomized controlled trial tested the hypothesis that addition of N-acetyl cysteine (NAC) can increase the probability of pregnancy in intracytoplasmic sperm injection (ICSI) cycles using the long agonist protocol. Women undergoing ICSI cycles due to male factor were randomly assigned to receive either long protocol (group A, 38 women) ...
Coskun Serdar - - 2010
OBJECTIVES: The aim of this study was to investigate the prognosis in future IVF cycles of patients with empty follicle syndrome (EFS). STUDY DESIGN: EFS cases and their future cycles were reviewed. Clinical pregnancy rate per started cycle was taken as the primary outcome in assessing the future outcome in ...
Farhi Jacob - - 2010
AIMS: To compare the results of IVF cycles following coasting in patients treated with long versus short GnRH agonist protocols. METHODS: A retrospective comparative study in which all women aged 35 years or less attending the IVF unit from 2000 to 2006 in whom coasting was used in GnRH agonist ...
Requena Antonio - - 2010
OBJECTIVE: To assess if the luteinizing hormone/human chorionic gonadotropin present in some gonadotropin formulations may be of benefit in protocols with GnRH antagonists. METHODS: Open, quasi-experimental, multicenter, prospective, parallel-controlled study compared 136 women undergoing in vitro fertilization--intracytoplasmic sperm injection after stimulation with highly purified human menopausal gonadotropin (hp-hMG) (n = ...
Li H W Raymond - - 2010
Gonadotrophin-induced ovulation (GnOI) is generally an effective treatment when anti-estrogen therapy is unsuccessful. It remains uncertain how appropriate it is in older and obese women. We carried out an analysis of a GnOI programme between 2000 and 2008, including 514 treatment cycles in 140 women with World Health Organisation Group ...
Cheong Ying - - 2010
The objectives of this systematic review were to determine the effectiveness of (a) acupuncture and (b) Chinese herbal medicine on the treatment of male and female subfertility by assisted reproductive technologies (ART). All reports from RCTs of acupuncture and/or Chinese herbal medicine in ART were obtained via searches through The ...
Kim Yong Jin - - 2010
PURPOSE: This study was performed to compare the outcomes of controlled ovarian stimulation (COH) and IVF between women with PCOS and those with sonographic PCO-only in GnRH antagonist cycles. METHODS: This was a retrospective study of women with PCOS (n = 42) and those with sonographic PCO-only (n = 54) ...
Risso A - - 2010
Two experiments were conducted to investigate the effects of the GnRH antagonist acyline (330 microg/kg, given sc) on ovarian follicular development and ovulation, as well as on pregnancy maintenance in domestic cats. In the first experiment, seven queens in proestrus (total of 24 proestrus periods), were randomly assigned to treatment ...
Norian John M - - 2010
To examine cycle outcomes among patients demonstrating an attenuated ovarian response that proceeded to oocyte retrieval to those converted to intrauterine insemination (IUI). Retrospective cohort study. Large private fertility center. First planned autologous assisted reproductive technology (ART) cycles among women demonstrating a poor ovarian response to hyperstimulation (≤4 follicles≥14 mm, ...
Gholami H - - 2010
OBJECTIVE: To compare the pregnancy outcome in patients undergoing in vitro fertilization-embryo transfer (IVF-ET) cycles, using human derived follicle-stimulating hormone (FSH) or recombinant FSH for ovarian stimulation protocols. DESIGN: Prospective, multi-centre, randomized controlled trial. PATIENTS: 115 infertile patients undergoing a first attempt of in vitro fertilization and embryo transfer were ...
Ercan Cihangir Mutlu - - 2010
Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrinopathy and a major cause of infertility. PCOS may be associated with chronic anovulation and endometrial hyperplasia. Conservative treatment should be considered in young women wishing to preserve their fertility. Standard treatment for complex endometrial hyperplasia is the use ...
Fatemi Human Mousavi - - 2010
To assess whether there is a difference in the ongoing pregnancy rate after transferring frozen-thawed embryos in natural cycles with spontaneous LH-P rise compared with natural cycles controlled by hCG for final oocyte maturation and ovulation. Randomized controlled trial. Tertiary referral center. A total of 168 patients were assigned randomly ...
Kilic Sevtap - - 2010
OBJECTIVE: Ovarian responsiveness to ovulation induction agents is essential for a successful clinical outcome in assisted reproductive technology (ART) cycles. We aimed to evaluate the accuracy of multinominal logistic models for the prediction of ovarian reserve and pregnancy in women undergoing ART cycles. PATIENTS AND METHODS: 1,970 patients who underwent ...
Stuckey Bronwyn G A - - 2010
OBJECTIVE: Our objective is to report observed changes in thyroid-stimulating hormone (TSH) in two patients undergoing super-ovulation for IVF. DESIGN: Case report. SETTING: Private assisted reproduction practices. PATIENT(S): Two hypothyroid women taking thyroxine replacement therapy undergoing super-ovulation for IVF. INTERVENTION(S): Laboratory records for TSH taken during ovulation induction cycles were ...
Check J H - - 2010
To demonstrate the benefits of using lower dosage FSH stimulation for follicular maturation in in vitro fertilization (IVF) cycles and in non-IVF cycles. Several studies are evaluated in which either high or lower dosage gonadotropins were used in IVF and non-IVF cycles. The patient population were women either with diminished ...
Badawy A - - 2010
The objective of this study was to test the use of letrozole in combination with follicle-stimulating hormone (FSH) vs clomiphene citrate (CC) with FSH for ovarian hyperstimulation prior to intrauterine insemination (IUI). A prospective randomised trial in which 280 women with unexplained infertility were randomised to 100 mg of CC ...
Zeinalzadeh Mahtab - - 2010
OBJECTIVE: To compare the efficacy of letrozole with clomiphene citrate for ovulation induction in patients with polycystic ovarian syndrome (PCOS). STUDY DESIGN: In this clinical trial, 107 infertile patients with PCOS received either 100 mg clomiphene citrate (n = 57) or 5 mg letrozole (n = 50) daily since day ...
Pelinck Marie-Jos? - - 2010
OBJECTIVE: Singletons born after IVF treatment are at risk for adverse pregnancy outcome, the cause of which is unknown. The aim of the present study was to investigate the influence of ovarian stimulation on perinatal outcome. STUDY DESIGN: In this single-centre retrospective study, perinatal outcome of singleton pregnancies resulting from ...
Narvekar Sachin A - - 2010
Management of repeated implantation failure despite transfer of good-quality embryos still remains a dilemma for ART specialists. Scrapping of endometrium in the nontransfer cycle has been shown to improve the pregnancy rate in the subsequent IVF/ET cycle in recent studies. The objective of this randomized controlled trial (RCT) was to ...
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