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Results 101 - 150 of 1154
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Cooley Sharon M - - 2010
AIMS: To investigate the relationship between levels of insulin-like growth factors 1 and 2 (IGF-1, IGF-2), and insulin-like growth factor binding protein 3 (IGFBP-3) in antenatal maternal serum and gestational age at delivery. METHODS: Prospective cohort study of 1650 low-risk Caucasian women in a London University teaching hospital. Maternal IGF-1, ...
Danesh Azar - - 2010
OBJECTIVES: The aim of this study was to assess the effect of high dose zinc (Zn) supplement during pregnancy in pregnancy outcome in healthy pregnant women with a previous preterm delivery in Isfahan, Iran. METHODS: A double-blind placebo-controlled randomized clinical trial was conducted between January 2007 and June 2008. Eighty-four ...
Walsh Jennifer - - 2010
Cervical cerclage may be indicated in specific clinical situations in an attempt to reduce the risk of preterm delivery. Preterm prelabour rupture of membranes (PPROM) occurs sometimes in the presence of a cerclage, and these pregnancies are at substantial risk of adverse maternal, fetal, and neonatal outcomes that may be ...
Romero Roberto - - 2010
The purpose of this study was to determine whether maternal/fetal single nucleotide polymorphisms (SNPs) in candidate genes are associated with spontaneous preterm labor/delivery. A genetic association study was conducted in 223 mothers and 179 fetuses (preterm labor with intact membranes who delivered <37 weeks of gestation [preterm birth (PTB)]), and ...
Chmait Ramen H - - 2010
OBJECTIVE: Vasa previa is associated with increased perinatal morbidity and mortality because of fetal exsanguination at time of membrane rupture. We report our experience in the treatment of type II vasa previa via in utero laser ablation in the third trimester. METHODS: Two cases of type II vasa previa were ...
Melamed Nir - - 2010
OBJECTIVE: To assess the effect of fetal gender on pregnancy outcome. METHODS: Retrospective study of all singleton pregnancies at a tertiary hospital during 1995-2006. RESULTS: Of the 66,387 women studied, 34,367 (51.8%) delivered male and 32,020 (48.2%) delivered female neonates. The rate of preterm delivery (as early as 29 weeks) ...
Genc Mehmet R - - 2010
PURPOSE OF REVIEW: There is overwhelming evidence that intrauterine infection and inflammation play an important role in the pathogenesis of spontaneous preterm labor, preterm prelabor rupture of the membranes and fetal injury resulting in long-term sequelae. Early diagnosis of subclinical infection and inflammation may therefore aid clinicians institute interventions focusing ...
Lata Indu - - 2010
This study was undertaken to estimate the incidence of bacterial vaginosis (BV) and other vaginal infections during pregnancy and its association with urinary tract infections (UTI) and its consequences on pregnancy outcome, maternal and fetal morbidity and mortality. Prospective cohort study. The present prospective cohort study was conducted on 200 ...
Patel Kunjal - - 2010
Conflicting results have been reported among studies of protease inhibitor (PI) use during pregnancy and preterm birth. Uncontrolled confounding by indication may explain some of the differences among studies. In total, 777 human immunodeficiency virus (HIV)-infected pregnant women in a prospective cohort who were not receiving antiretroviral (ARV) treatment at ...
Kim Chong Jai - - 2010
Acute chorioamnionitis is a well-established lesion of the placenta in cases with intra-amniotic infection. In contrast, the clinicopathological significance of chronic chorioamnionitis is unclear. This study was conducted to determine the frequency and severity of chronic chorioamnionitis in normal pregnancy and in various pregnancy complications. Placentas from the following patient ...
DiGiulio Daniel B DB Department of Medicine, Stanford University School of Medicine, Stanford, CA, - - 2010
The role played by microbial invasion of the amniotic cavity (MIAC) in preterm pre-labor rupture of membranes (pPROM) is inadequately characterized, in part because of reliance on cultivation-based methods. Amniotic fluid from 204 subjects with pPROM was analyzed with both cultivation and molecular methods in a retrospective cohort study. Broad-range ...
Briese Volker - - 2011
In the present study, the efficacy and tolerability of the local acting antiseptic octenidine hydrochloride/phenoxyethanol (OHP) for the treatment of vaginal dysbiosis (VD) and/or bacterial vaginosis (BV) in pregnancy and its potential influence on preterm births and low-weight newborns were examined. One-hundred nine pregnant women with increased pH values (>4.5) ...
Papanna R - - 2010
OBJECTIVE: To examine the incidence of preterm premature rupture of membranes (PPROM) in pregnancies affected by twin-twin transfusion syndrome (TTTS) treated with laser photocoagulation where an absorbable gelatin sponge was used as a chorioamnion sealant of the fetoscopic access port. METHOD: A retrospective review was undertaken of consecutive cases undergoing ...
Werner Claudia L - - 2010
OBJECTIVE: To examine whether preterm birth is related to the loop electrosurgical excision procedure (LEEP) itself or intrinsic to the women undergoing the procedure. METHODS: Rates of preterm birth, defined as births before 37 weeks of gestation, as well as causes were analyzed in women undergoing LEEP before or after ...
Refuerzo Jerrie S JS Department of Obstetrics and Gynecology at University of Texas Health Science Center at Houston, Houston, Texas 77030, USA. - - 2010
We compared neonatal outcomes in twin pregnancies following moderately preterm birth (MPTB), late preterm birth (LPTB), and term birth. A secondary analysis of a multicenter, randomized controlled trial of multiple gestations was conducted. MPTB was defined as delivery between 32 (0)/(7) and 33 (6)/(7) weeks and LPTB between 34 (0)/(7) ...
Bosetti Cristina - - 2010
To review epidemiologic evidence on maternal exposure to particulate matter and adverse pregnancy outcomes, we performed a MEDLINE search of the literature up to June 2009. We considered all original studies published in English including information on total suspended particles (TSP), respirable (PM(10)) or fine (PM(2.5)) particles and the risk ...
Rosier-van Dunn? Fleur M - - 2010
BACKGROUND: In preterm born infants abnormal general movements (GMs) generally normalize before three months post term, but may persist when perinatal brain injury is present. AIMS: To assess the continuity of GM quality from fetal to early neonatal period and its relation to brain echogenicity changes. STUDY DESIGN: Prospective study ...
Ali Yuce Mehmet - - 2010
The incidence of multiple pregnancies is increasing with the availability of assisted reproductive techniques. Preterm labor and preterm rupture of membranes are major complications in such pregnancies. Preterm delivery of the first fetus is often followed by delivery of the remaining fetuses. However, conservative management in such circumstances might allow ...
Mazaki-Tovi Shali - - 2010
Adiponectin, an anti-inflammatory and anti-diabetogenic adipokine, has an important regulatory effect on both the innate and adaptive limbs of the immune response. The objective of this study was to determine whether adiponectin is present in amniotic fluid (AF) and if its concentration changes with gestational age, in the presence of ...
Chi Ching-Chi - - 2010
Pregnant women may have skin conditions that require topical corticosteroids. However, little is known about their safety in pregnancy. We sought to evaluate the available evidence concerning the safety of topical corticosteroids in pregnancy. We systematically searched 17 databases and trial registers, and contacted pharmaceutical companies. Randomized controlled trials and ...
Suhag Anju - - 2010
We estimated the optimal gestational age for placement of a history-indicated cerclage in a retrospective cohort study of pregnancies during the period between 1994 to 2007. Pregnancies were divided into two groups: group 1, cerclage <14 weeks (N = 83), and group 2, cerclage >or=14 weeks (N = 59). The ...
Donders Gilbert G - - 2010
AIM.: To study the relationship between abnormal vaginal flora (AVF) in the first trimester as a risk factor for shortening cervix length (CL) at second and third trimester, and to assess the combination of these factors in predicting preterm delivery. METHODS.: 1026 unselected low risk women seen before 16 weeks ...
Luewan Suchaya - - 2011
To determine maternal and fetal outcomes of women complicated with hyperthyroidism compared with those in normal pregnant women. This cohort study was conducted on singleton pregnant women complicated by hyperthyroidism without other medical complications between January 1994 and December 2008, at tertiary center. The normal controls were identified to match ...
Deffieux Xavier - - 2010
OBJECTIVE: To report fertility and pregnancy outcomes following transvaginal cervicoisthmic cerclage with a polypropylene sling during a previous pregnancy. METHODS: A continuous series of 57 women who underwent prophylactic cervicoisthmic cerclage during a previous (reference) pregnancy were enrolled. Telephone interviews were carried out to evaluate each patient's subsequent fertility. RESULTS: ...
Balci Osman - - 2010
To evaluate the effect of antenatal treatment with a single dose of betamethasone between the 34th and the 36th week of pregnancy on the maturation of fetal lung. To study 100 pregnant women in their 34th-36th week of pregnancy who were diagnosed as susceptible to have preterm delivery. Fifty patients ...
Ugwumadu Austin - - 2010
Mid-trimester pregnancy loss defined as miscarriage at 14-23 weeks' gestation and preterm birth between 24 and 28 weeks are in essence clinical manifestations of the same disease process. The pathogenic and socio-biologic risk factors are the same, but the timing of onset of uterine activity and cervical dilatation may be ...
Tara F - - 2010
The aim was to determine if selenium supplementation during pregnancy reduces the occurrence of premature (pre-labour) rupture of membranes (PROM). A total of 166 primigravid pregnant women in the first trimester of pregnancy, were randomised to receive 100 microg of selenium (n = 83, drop-outs = 22) or a placebo ...
Einarson A - - 2010
OBJECTIVE: To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy. METHODS: At The Motherisk Program, we analyzed pregnancy outcomes of 1,243 women in our database who took various antidepressants ...
Di Ferdinando A - - 2010
This work stands as a pilot study in assessing the reliability of metalloproteinase-9 (MMP-9) as a marker for intraamiotic infection and preterm birth already in early pregnancy. 100 amniotic fluids taken at the Midwife Obstetrics and Gynaecological Clinic of the University of L'Aquila (Italy). Our results show that MMP-9 is ...
Seki N - - 2010
OBJECTIVE: The purpose of the present study was to evaluate the efficacy of diagnostic laser conization and the obstetric outcomes of patients undergoing diagnostic laser conization during pregnancy. STUDY DESIGN: The study population consisted of a consecutive series of 47 patients who presented with histologically proven carcinoma in situ microinvasive ...
Becher Naja - - 2010
High concentrations of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have been identified in the cervical mucus plug (CMP) at term of pregnancy. Their physiological and pathophysiological implications, however, remain to be elucidated, and CMPs from preterm labor have never been examined. This study was therefore conducted to ...
Sokolowski Peter - - 2010
Uterine wall tension is thought to be an important determinant of the onset of labor in pregnant women. We characterize human uterine wall tension using ultrasound from the second trimester of pregnancy until parturition and compare preterm, term and twin pregnancies. A total of 320 pregnant women were followed from ...
Gravett Michael G - - 2010
Normal and abnormal processes of pregnancy and childbirth are poorly understood. This second article in a global report explains what is known about the etiologies of preterm births and stillbirths and identifies critical gaps in knowledge. Two important concepts emerge: the continuum of pregnancy, beginning at implantation and ending with ...
Kusanovic Juan Pedro - - 2010
Intra-amniotic infection/inflammation (IAI) is one of the most important mechanisms of disease in preterm birth. Triggering receptor expressed on myeloid cells (TREM)- 1 is a transmembrane glycoprotein expressed by neutrophils, macrophages and mature monocytes. TREM-1 is upregulated in biological fluids and tissues infected by Gram (+) and Gram (-) bacteria ...
Alexander Sophie - - 2010
Repeat digital cervical assessment (RDCA - examination of the cervix with a finger) has been promoted as a routine intervention in the antenatal clinic as a screening test for the risk of preterm birth (that is, birth occurring before 37 weeks of gestation). To assess the effect of repeat digital ...
Lyon Debra - - 2010
Preterm birth (PTB; spontaneous delivery prior to 37 weeks gestation) affects one out of eight infants born in the United States and is the most common cause of neonatal morbidity and mortality. Although the pathogenesis of PTB is multifactorial, a growing body of literature supports the hypothesis that one cause ...
Singla Anshuja - - 2010
OBJECTIVE: To evaluate the effect of transabdominal amnioinfusion on prolongation of pregnancy, and maternal and neonatal outcomes in preterm premature rupture of membranes (pPROM). METHODS: We conducted a prospective randomized controlled study of women with pPROM during singleton live pregnancy-between 26 and 33+6weeks-whose amniotic fluid index (AFI) was less than ...
Clifton Vicki L - - 2009
OBJECTIVE: To determine if there are sex differences in risk and incidence of stillbirth, preterm delivery and small-for-gestational age (SGA) in pregnancies complicated by maternal asthma relative to a non-asthmatic population. STUDY DESIGN: Univariant and multiple regression analysis of the incidence of preterm delivery, SGA and stillbirth in singleton pregnancies ...
Kusanovic Juan Pedro - - 2009
Circulating soluble human leukocyte antigen-G (sHLA-G) has been associated with pregnancy complications, and determination of sHLA-G concentrations in amniotic fluid (AF) has been reported in normal pregnancies. Our aim was to determine if the AF concentrations of sHLA-G change with advancing gestation, spontaneous labor at term, and in patients with ...
Goldenberg Robert L - - 2009
OBJECTIVES: To estimate women's understanding of the definition of full term and the gestational age at which it is safe to deliver an otherwise healthy pregnancy. METHODS: A national sample of 650 insured women who recently gave birth were surveyed about their beliefs related to the meaning of full term ...
Fox Nathan S - - 2009
OBJECTIVE: To determine whether pregnancy associated plasma protein-A (PAPP-A) can be used to identify pregnancies at risk for poor perinatal outcomes among patients with second trimester fetal growth restriction (FGR). METHODS: We analyzed outcomes for singleton pregnancies of patients with evidence of FGR in the second trimester who also had ...
Chaiworapongsa Tinnakorn - - 2009
An imbalance between angiogenic and anti-angiogenic factors in maternal blood has been observed in several obstetrical syndromes including preeclampsia, pregnancies with fetal growth restriction and fetal death. Vascular lesions have been identified in a subset of patients with spontaneous preterm labor (PTL). It is possible that PTL may be one ...
van de Vijver A - - 2010
OBJECTIVE: To assess pregnancy outcome after conisation. DESIGN: Retrospective cohort study. SETTING: Belgium, data from a university hospital. POPULATION: Fifty-five pregnancies in 34 women after conisation, and 55 pregnancies in 54 women without a history of conisation or cervical intraepithelial neoplasia (CIN). METHODS: Hospital data were reviewed and questionnaires were ...
Ortoft G - - 2010
OBJECTIVE: To determine the effects of one or two conisations on preterm delivery and perinatal mortality in subsequent pregnancies. DESIGN: A population-based cohort study. SETTING: Aarhus University Hospital. POPULATION: Preterm delivery and mortality rates were evaluated in 721 deliveries after one conisation, and in 37 deliveries after two conisations, and ...
Piccoli Giorgina Barbara - - 2010
Although successful pregnancy is rare, results attained with higher dialysis efficiency and the spread of dialysis to different cultural and religious settings are changing the panorama. In this study, we systematically review the recent literature (2000 through 2008) on pregnancy in dialysis. Medline on OVID was searched in November 2008, ...
Belkin Avner - - 2009
OBJECTIVE: To investigate pregnancy and perinatal outcomes in women with immune thrombocytopenic purpura (ITP). METHODS: A retrospective study comparing all singleton pregnancies of women with and without ITP was conducted. Deliveries occurred between the years 1988 and 2007. Multiple logistic regression models were performed to control for confounders. RESULTS: During ...
Apel-Sarid Liat - - 2010
The present study was aimed to compare term versus preterm placental pathologies associated with fetal growth restriction (FGR). A retrospective cohort study was performed, including all singleton deliveries of FGR with placental pathology examination. Comparison of placental findings was performed between neonates who were born at term versus preterm. Preterm ...
Jensen Dorte M - - 2010
To study the association between microalbuminuria and development of preeclampsia and preterm delivery in pregnant women with type 1 diabetes. This was a population-based prospective study in 846 normoalbuminuric or microalbuminuric women with type 1 diabetes without antihypertensive treatment in early pregnancy. Data were collected prospectively by one to three ...
Fox Nathan S - - 2010
We sought to evaluate the change in cervical length (CL) as a predictor of preterm birth in asymptomatic twin pregnancies. We studied a historical cohort of 121 twin pregnancies with CL testing between 18-24 weeks who had a follow-up CL 2-6 weeks after the initial CL. A total of 19 ...
Flick Amy A - - 2010
We examined pregnancy outcomes in women receiving nifedipine tocolysis having recurrent preterm labor (RPTL). Singleton gestations enrolled for outpatient nursing surveillance and prescribed nifedipine tocolysis were identified (N = 4748). Women hospitalized for RPTL at <35 weeks then resuming outpatient surveillance were included (N = 1366). Pregnancy outcomes of women ...
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