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Results 51 - 100 of 1151
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Jawaheer Damini D Children's Hospital Oakland Research Institute, Oakland, California 94609, USA. - - 2011
To assess whether onset of rheumatoid arthritis (RA) prior to conception is associated with a delayed time to pregnancy (TTP). The study included pregnant women from across Denmark who enrolled in the Danish National Birth Cohort between 1996 and 2002 and had planned or partly planned the cohort pregnancy. RA ...
Van Calsteren K - - 2011
Based on an estimated incidence of cancer during pregnancy of 1 per 1000-1500 pregnancies, annualy 3000-5000 new patients can be expected in Europe. The treatment of cancer in pregnant women is a challenge since both the maternal and the foetal well-being need to be considered. This study was initiated to ...
Scioscia Crescenzio - - 2011
Rheumatoid arthritis is associated with an increased risk of adverse pregnancy outcomes. TNF inhibitors are effective in the treatment of signs and symptoms of the disease although their safety during pregnancy is debated. Two cases of women with rheumatoid arthritis in complete remission of the disease with etanercept who decided ...
van de Geijn Fleur E - - 2011
Rheumatoid arthritis (RA) improves during pregnancy and flares after delivery. It has been hypothesized that high levels of the complement factor mannose-binding lectin (MBL) are associated with a favourable disease course of RA by facilitating the clearance of pathogenic immunoglobulin G (IgG) lacking galactose sugar moieties. During pregnancy, increased galactosylation ...
Jauniaux Eric - - 2010
To evaluate the impact of early pregnancy complications involving placentation and early placental development on adverse obstetric outcome in ongoing and subsequent pregnancies. We found an increased risk of adverse outcome (odds ratio >2.0) in ongoing pregnancies of preterm delivery (PTD), very preterm delivery (VPTD), placental abruption, small for gestational ...
Fox Nathan S - - 2010
The purpose of this study was to define normal second-trimester cervical length (CL) measurements and to estimate the association between second-trimester CL and spontaneous preterm birth (SPTB) in twin pregnancies. A retrospective cohort of 309 asymptomatic patients with twin pregnancies who had routine outpatient CL assessment in the second trimester ...
Smith Graeme N - - 2010
This secondary analysis of a randomized placebo-controlled trial was to hypothesize on mechanisms for the improved neonatal outcomes with the use of nitroglycerin (GTN) for preterm labor. Women in the original trial who delivered at term were excluded. A composite of severe neonatal outcomes, gestational age at delivery, and corticosteroid ...
Stock Sarah - - 2010
The association between multiple pregnancy and preterm labour is well-established, with >50% of multiple births delivering before 37 weeks. However, there remains limited understanding of the factors predisposing to early delivery of twins. Physiological stimuli to the onset of parturition, including stretch, placental corticotrophin-releasing hormone and lung maturity factors, may ...
Conde-Agudelo Agustín - - 2010
To investigate the accuracy of cervicovaginal fetal fibronectin in predicting preterm birth in women with multiple pregnancies. Systematic review and meta-analysis of predictive test accuracy. Cohort or cross-sectional studies were identified through searches in databases, reference lists, proceedings, and reviews. Study selection, quality assessment, and data extraction were performed. We ...
Wikström Anna-Karin - - 2011
We hypothesized that preeclampsia partly shares pathophysiology with stillbirth, placental abruption, spontaneous preterm birth, and giving birth to a small-for-gestational-age infant, and that women who develop preeclampsia in the first pregnancy may have increased risks of the other outcomes in the second pregnancy, even in the absence of preeclampsia. In ...
Jnifen Asma - - 2010
Background: Pregnancy beyond age 40 is considered as a high risk pregnancy associated with high rates of maternal and fetal complications. Aim: To analyze particularities of pregnancy and labor and to examine obstetrical and neonatal outcomes among women age 40 years and older. Methods : There was a retrospective study ...
Omokhodion Folashade O - - 2010
To identify the determinants of low birth weight (LBW), preterm birth, and stillbirth, and the factors associated with paid or domestic work that affected pregnancy outcome in Ibadan, Nigeria. A cross-sectional study of women who delivered live or stillborn singleton neonates at 4 hospitals between February and June 2008. Participants ...
Szekessy D P - - 2010
Focal and symmetric necrotic lesions of the brainstem are thought to result from fetal hypotension or cardiac arrest in the perinatal period and thus occur in the course of postnatal intensive care rather than in utero. Here, we report for the first time on brainstem necrosis in a preterm stillborn ...
Weintraub Adi Y - - 2011
To investigate whether colonization with GBS in a previous pregnancy is associated subsequently with adverse obstetric and perinatal outcomes. A retrospective study was undertaken comparing pregnancy complications of patients with and without colonization with GBS in a previous pregnancy from 1988 to 2006. Women with a positive GBS culture in ...
Jones Nicole M - - 2010
Recent findings suggest that the association between inflammation-related genes and preterm delivery may be stronger in the presence of bacterial vaginosis (BV). Tumor necrosis factor-alpha (TNFα) and interleukin 1-beta (IL-1β) are pro-inflammatory cytokines capable of inducing preterm labor in non-human primates. In this study the authors tested associations among two ...
Llop Sabrina - - 2010
Research has shown that prenatal exposure to air pollutants may have a detrimental effect on fetal development, with the strength of the relationship depending on the effect being studied. The evidence to date, however, is insufficient to establish a direct causal link between such exposure and preterm delivery. This study ...
Klein Katharina - - 2010
The incidence of preterm delivery has been increasing, and our aim was to estimate the influence of fetal sex on the risk of preterm delivery in dichorionic twins after spontaneous conception. 125 spontaneously conceived dichorionic twin gestations, with viable fetuses, born after 24 weeks and delivered spontaneously before 37 weeks, ...
Morken Nils-Halvdan - - 2011
To assess the risk of spontaneous and iatrogenic preterm delivery in singleton pregnancies when comparing in vitro fertilization (IVF) pregnancies with intracytoplasmic sperm injection (ICSI) pregnancies. A national population-based cohort study using Norwegian Medical Birth Register data during 1999 through 2006 was designed. The cohort included 5824 singleton pregnancies after ...
Ratzon Ronit - - 2011
To assess the independent role of prenatal care in preventing recurrent preterm delivery (<37 weeks gestation) and in reducing adverse pregnancy outcomes in recurrent preterm delivery. A population-based retrospective cohort study. Participants were 1470 Bedouin women in Southern Israel who at their first delivery (parity 1) gave birth preterm (<37 ...
Zlatnik Marya G - - 2010
To determine the optimal gestational age of delivery for women with placenta previa by accounting for both neonatal and maternal outcomes. A decision-analytic model was designed comparing total maternal and neonatal quality-adjusted life years for delivery of women with previa at gestational ages from 34 to 38 weeks. At each ...
Hernandez Rohini K - - 2010
Despite the frequent intake of decongestants during pregnancy, only one study to date has evaluated the association of decongestants with preterm delivery, and it identified a reduced risk. We examined this association in more detail. Using a population-based random sample of 3271 Massachusetts live-born births without major malformations, we categorized ...
Singhal Savita Rani - - 2010
Arthrogryposis multiplex congenita (AMC) is a symptom complex of congenital joint contractures associated with neurogenic and myopathic disorders. It is diagnosed at birth and often progresses to a state of significant disability. Pregnancy in a woman with AMC is at high risk due to diminished pulmonary reserve, increased risk of ...
Hofmeister Carolina - - 2010
To compare cervical length (CL) at 18-21 and 22-25 weeks' gestation in twin pregnancies in prediction of spontaneous preterm delivery and to examine cervical shortening. Retrospective cohort study of CL measured at 18-21 and 22-25 weeks' gestation in twin pregnancies. Receiver operating characteristics (ROC) curve revealed area of 0.64 (95% ...
Watson Lyndsey F - - 2010
The prevalence and intractability of preterm birth is known as is its association with reproductive history, but the relationship with sequence of pregnancies is not well studied. The data were from a population-based case-control study, conducted in Victoria, Australia. The study recruited women giving birth between April 2002 and April ...
Lin Chia-Hui - - 2010
Intact amniotic membranes may serve to protect the extremely fragile preterm infant from some of the mechanical forces caused by strong uterine contraction. This article introduces the technique of "en caul" cesarean delivery and reviews the experience of the National Taiwan University Hospital. This is a prospective study carried out ...
Motazedian Shahdokht - - 2010
Preterm labor (PTL) is a common medical problem during pregnancies and is associated with neonatal mortality and morbidity. Beta-adrenergic agonists are among the most commonly used tocolytic agents. The aim of this study was to compare the effectiveness, safety and adverse effects of terbutaline with those of salbutamol in the ...
Vigeh Mohsen - - 2011
Objectives Although occupational and environmental exposures to lead have been dramatically reduced in recent decades, adverse pregnancy outcomes have been observed at 'acceptable' levels of blood lead concentrations (≤10 μg/dl). Methodology Blood samples were collected from 348 singleton pregnant women, aged 16-35 years, during the first trimester of pregnancy (8-12 weeks) for lead ...
Gehring Ulrike - - 2011
Objectives There is growing evidence for an adverse effect of maternal exposure to air pollution on pregnancy outcomes. As European data on this topic are limited, the aim of this study was to evaluate the impact of maternal exposure to traffic-related air pollution during different periods of pregnancy on preterm ...
Jelliffe-Pawlowski Laura L - - 2010
To examine the relationship between typically collected second trimester maternal serum biomarkers and preterm birth among pregnancies without intrauterine-growth-retardation or other specific risk factors. Included were 102 861 singleton pregnancies without specific risks that resulted in the live birth of an infant of normal birth weight for gestational age without ...
Ananth Cande V - - 2010
OBJECTIVE: Preeclampsia, small for gestational age (SGA), and abruption are considered ischemic placental diseases (IPD), and are major contributors to both maternal and fetal morbidity and mortality. Although the placenta is considered a fetal organ, these conditions can present clinically with either maternal or fetal manifestations, but their relationship to ...
Norman Shayna M - - 2010
OBJECTIVE: To estimate the association between the ultrasonographic diagnosis of subchorionic hemorrhage and adverse pregnancy outcomes. METHODS: This was a retrospective cohort study of all consecutive women undergoing routine ultrasonography before 22 weeks with a singleton gestation at one institution from 1994 to 2008. Presence or absence of subchorionic hemorrhage ...
Petraglia Felice - - 2010
The complex mechanisms controlling human parturition involves mother, fetus, and placenta, and stress is a key element activating a series of physiological adaptive responses. Preterm birth is a clinical syndrome that shares several characteristics with term birth. A major role for the neuroendocrine mechanisms has been proposed, and placenta/membranes are ...
Butt Fatima T - - 2011
Objective.?The purpose of this study was to evaluate the role of transabdominal amnioinfusion in the management of oligohydramnios with the view to improving pregnancy outcome. Methods.?The study consisted of a retrospective analysis of 17 pregnant women presenting with oligohydramnios who were treated with amnioinfusion during pregnancy in a period from ...
Diav-Citrin Orna - - 2010
OBJECTIVE: We sought to examine the fetal safety of colchicine. STUDY DESIGN: This was a prospective observational comparative cohort study regarding colchicine exposure during pregnancy including contacts to 2 Teratology Information Services in Israel from 1994 through 2006. RESULTS: In all, 238 colchicine-exposed pregnancies (97.0% first trimester) and 964 pregnancies ...
Roman A - - 2010
To compare radiofrequency ablation (RFA) and bipolar cord coagulation (BPC) methods for selective fetal reduction in the treatment of complicated monochorionic (MC) multifetal gestations. This was a retrospective review of patients who underwent selective reduction by RFA and BPC. Computer-generated random sampling was performed to match patients who had undergone ...
Haddow James E - - 2010
OBJECTIVE: To further evaluate the relationship between thyroid antibodies and preterm births. METHODS: This is a prospective study of pregnancy outcome and demographic data combined with retrospective measurement of thyroperoxidase and thyroglobulin antibodies. Sera were obtained at 11-13 and 15-18 weeks of gestation from 10,062 women with singleton viable pregnancies ...
Mercer Brian M - - 2010
Generation of reactive oxygen species (ROS) has been suggested as a mechanism of fetal membrane (FM) weakening leading to rupture, particularly with preterm premature rupture of the fetal membranes (PROM). In vitro, FM incubation with tumor necrosis factor (TNF) mimics physiological FM weakening, concomitant with generation of ROS and collagen ...
Phillips Julie K JK Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Vermont, Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, Vermont, USA. - - 2010
To determine differences in maternal and fetal characteristics in pregnancies complicated by preterm versus term preeclampsia. Using our electronic database we identified 143 women who met the American College of Obstetricians and Gynecologists criteria for preeclampsia between January 1995 and August 2003. We collected data on age, smoking status, maternal ...
Aggarwal Neelam - - 2011
Autoimmune hepatitis (AIH) is a chronic disease of unknown cause, characterized by progressive hepatocellular inflammation and necrosis, frequently leading to cirrhosis. AIH usually affects young women and may influence fertility and pregnancy in them. Nearly 200 pregnancies have been reported so far in the world literature in women with AIH, ...
Conde-Agudelo Agustín - - 2010
To assess the accuracy of transvaginal sonographic cervical length (CL) in predicting spontaneous preterm birth in women with twin pregnancies. Systematic review and metaanalysis of predictive test accuracy. Twenty-one studies (16 in asymptomatic women and 5 in symptomatic women) with a total of 3523 women met the inclusion criteria. Among ...
Moscuzza Francesca - - 2011
Introduction. Placental anatomopathologic lesions are usually associated with pregnancy complications and neonatal impaired outcome. Patients and methods. We included in our study 122 patients with gestational age of 26-35 weeks. From the analysis of three pathological aspects (chorioamnionitis, funisitis and chronic hypoxia), a score was assigned to each lesion depending on the ...
Lim Jenny J Y - - 2010
OBJECTIVE: To estimate maternal and neonatal outcomes in women with preterm prelabour rupture of membranes (PPROM) who delivered at 34+0 to 36+6 weeks' gestation, particularly in those who had an obstetrically indicated delivery. METHODS: We conducted a population-based study of late preterm singleton births complicated by PPROM, using data from ...
Hallman Mikko - - 2010
Enhancing functional maturity of the high-risk preterm fetus is aimed at decreasing the life-threatening neonatal disorders that increase the burden of chronic disease. A course of antenatal glucocorticoids before 35 weeks of pregnancy substitutes endogenous activation of the hypothalamic-adrenal axis that spontaneously enhances functional maturity and augments cytokine-induced preterm lung ...
Oliveira Alcione Maria Soares Dutra - - 2011
Periodontitis has been associated with adverse pregnancy outcomes. Results from intervention studies are few and controversial. The present study assessed the effects of non-surgical periodontal treatment in the occurrence of adverse pregnancy outcomes. Two hundred forty-six eligible women were randomly divided into two groups: periodontitis intervention (n = 122; undergoing non-surgical treatment ...
Kang Jiunn-Horng - - 2010
Population-based data regarding pregnancy outcomes for patients who experienced stroke during pregnancy is sparse and mainly from Western populations. The authors investigate the association between strokes and pregnancy outcomes in Chinese women through a nationwide case-controlled study. A total of 161 women having live singleton births between 2001 and 2003 ...
Davis Jonathan M - - 2010
The study of the interplay of the generation of reactive oxygen and nitrogen species with their related antioxidant enzymes at the maternal-placental-fetal interfaces during normal and abnormal pregnancy is in its 'infancy'. Our understanding of the role of antioxidant systems during fetal and neonatal development is constantly changing with research ...
Elaveyini U - - 2011
This paper illustrates a retrospective study of the outcome of those pregnancies that continued from an initial episode of bleeding in first trimester. Neural networks is used for the prediction of preterm delivery, using various inputs such as the age of women, gestational age when the bleeding occurred, duration of ...
Cooley Sharon M - - 2010
AIMS: To investigate the relationship between levels of insulin-like growth factors 1 and 2 (IGF-1, IGF-2), and insulin-like growth factor binding protein 3 (IGFBP-3) in antenatal maternal serum and gestational age at delivery. METHODS: Prospective cohort study of 1650 low-risk Caucasian women in a London University teaching hospital. Maternal IGF-1, ...
Danesh Azar - - 2010
OBJECTIVES: The aim of this study was to assess the effect of high dose zinc (Zn) supplement during pregnancy in pregnancy outcome in healthy pregnant women with a previous preterm delivery in Isfahan, Iran. METHODS: A double-blind placebo-controlled randomized clinical trial was conducted between January 2007 and June 2008. Eighty-four ...
Walsh Jennifer - - 2010
Cervical cerclage may be indicated in specific clinical situations in an attempt to reduce the risk of preterm delivery. Preterm prelabour rupture of membranes (PPROM) occurs sometimes in the presence of a cerclage, and these pregnancies are at substantial risk of adverse maternal, fetal, and neonatal outcomes that may be ...
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