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Ozdemici Safak S Etlik Zubeyde Hanim Women's Health Education and Research Hospital, Ankara, - - 2014
Abstract Objective: To evaluate the influence of threatened miscarriage on obstetric complications during pregnancy and early postpartum period. Methods: In this case-control study, hospital records of 12,050 first-trimester patients between January 2011 and December 2012 at the Research and Educational Hospital in Ankara, Turkey, were used. Of the 12,050 patients, ...
Gordin Daniel D Division of Nephrology, Department of Medicine, Helsinki University Central Hospital , Helsinki , - - 2014
Diabetic women carry a 2-4 times increased risk of a hypertensive pregnancy compared to non-diabetic people. This risk is related to presence of diabetic nephropathy, but also poor glycaemic control. Efforts to improve glycaemic control have decreased perinatal morbidity and mortality related to diabetic nephropathy. Despite good glycaemic control, overt ...
Kappou D D 1st Department of Obstetrics and Gynaecology, University of Athens Medical School, Alexandra Hospital, Athens, Greece; Department of Obstetrics & Gynecology, University Hospital of Heraklion, Crete, Greece. Electronic address: - - 2014
To investigate the placental expression of angiopoietin (Ang)-1, Ang-2 and their receptor, Tie-2, in preeclampsia (PE) with or without intrauterine growth restriction (IUGR). Case-control study including placentas from 28 PE pregnancies, 30 PE-IUGR pregnancies and 40 controls. The expression status of the genes was evaluated by quantitative real-time PCR. In both PE ...
Vajda Frank J E FJ Departments of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, - - 2014
To assess the effectiveness of the newer antiepileptic drugs (AEDs)-in particular lamotrigine, topiramate, and levetiracetam-in controlling epileptic seizures in pregnant women. Analysis of data in the Australian Register of Antiepileptic Drugs in Pregnancy concerning seizure control in 1,534 pregnancies in women with AED-treated epilepsies. In AED monotherapy (1,111 pregnancies), use ...
Fan Xuemei X Departments of Ultrasonography (X.F., Q.Z., S.Z., J.Z., Q.P., M.Z.) and Obstetrics and Gynecology (Y.D.), Second Xiangya Hospital, Central South University, Changsha, - - 2014
To investigate changes in fetal myocardial deformation in intrahepatic cholestasis of pregnancy. Patients with intrahepatic cholestasis of pregnancy were divided into 2 groups according to the total maternal serum bile acid concentration: mild cholestasis (10-40 μmol/L) and severe cholestasis (>40 μmol/L). Fetal echocardiography and velocity vector imaging were performed on ...
Ockhuijsen Henrietta D L HD Department of Reproductive Medicine and Gynaecology, University Medical Centre Utrecht, P.O. Box 85500, 3508, GA, Utrecht, The - - 2014
Pregnant women who have had miscarriages face challenges in responding to the loss of the previous pregnancy and the uncertainties of the early pregnancy that follows. The research question in this qualitative study was: How do women experience miscarriage, conception, and the early pregnancy waiting period, and what types of ...
Simsek Gokce G ENT Department, Faculty of Medicine, Kırıkkale University, 71450, Kirikkale, Turkey, - - 2014
Pregnancy seems to be related with a significant change in olfaction. Here, we investigate this theory by testing the odor identification abilities of uncomplicated pregnant women and compare the results with non-pregnant controls. The study included 31 healthy pregnant women in the first trimester (Group 1), 30 in the second ...
Tabatabaei Negar N School of Dietetics and Human Nutrition, McGill University, Ste-Anne-de-Bellevue, Quebec, - - 2014
The purpose of this study was to investigate circulating concentrations of osteocalcin, a bone-derived protein, while accounting for 25-hydroxyvitamin D (25(OH)D) throughout pregnancy, and whether early gestation concentrations and changes in osteocalcin predict the subsequent diagnosis of gestational diabetes mellitus (GDM). This was a nested case-control study involving 48 GDM ...
Moberg Christian C Department of Women's and Children's Health, Uppsala University , Uppsala , - - 2014
Endometriosis affects fertility in many women and may partly be due to decreased endometrial receptivity. Several mechanisms have been suggested, notably, progesterone resistance for which a number of candidate biomarkers have been suggested. Here we demonstrate aberrant levels of steroid hormone receptors and the small heat shock protein αB-crystallin in ...
Yadav Sonali S Department of Pathology, King George's Medical University, Lucknow, 226003, Uttar Pradesh, - - 2014
To identify whether CGRP and PTHrP serve as screening biomarkers for early detection of preeclampsia or even before the development of preeclampsia in early pregnancy. It was a nested case-control study. The subjects were divided into normotensive (controls) and preeclamptic (cases) groups. Serum samples of 132 cases and 132 controls ...
Kirbas Ayse A Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. Electronic address: - - 2014
In this study, we aimed to investigate the relationship between neutrophil-to-lymphocyte ratio (NLR) and total bile acid (TBA) concentration in pregnant women with intrahepatic cholestasis of pregnancy (ICP). Fasting and postprandial TBA, NLR, and aminotransferase (AST/ALT) levels in the blood samples of 65 pregnant women with intrahepatic cholestasis were examined ...
Coker Elise E Department of Women's Health, Royal North Shore Hospital, University of Sydney, Sydney, NSW, 2065, Australia, - - 2014
We examined prospectively changes in current BMI and body weight dissatisfaction in women with and without eating disorders (EDs) during and after pregnancy compared to prepregnancy. We assessed pregnant women with (ED group, N = 18) and without an ED (Control group, N = 129) using current BMI and the discrepancy between current and ...
Danve Abhijeet A Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97006. Electronic address: - - 2014
Pregnancy can lead to flares in systemic lupus erythematosus (SLE), and the presence of SLE in pregnancy could lead to a poor outcome for the mother and the fetus. To describe a patient whose active SLE (including lupus nephritis) was managed with the use of belimumab throughout pregnancy. A case ...
Meyer John D JD Icahn-Mount Sinai School of Medicine, New York, NY, USAUniversity of Connecticut Health Center, Farmington, CT, - - 2014
Pregnancy represents a dynamic period when both work conditions and worker assessment of occupational psychosocial stressors may change. We undertook longitudinal repeated measurements of job control, efforts, reward, and overcommitment in pregnant working women to assess direction and magnitude of change across pregnancy. The Job Content and Effort-Reward Imbalance (ERI) ...
Magee LA L University of British Columbia, Vancouver, - - 2014
Most obstetricians believe that BP normalisation in pregnancy reduces maternal complications, but may increase adverse perinatal outcomes. No adequately powered trials of differential BP control have been performed. Determine best management of non-severe pregnancy hypertension. In an open pragmatic international multicentre trial, women at 14(+0)-33(+6) wk gestation with non-proteinuric pre-existing ...
Beneventi Fausta F Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo and University of Pavia, Pavia, - - 2014
To target gestational diabetes mellitus (GDM) by means of temporal variation in pregnancy-associated plasma protein A (PAPP-A) and soluble human leukocyte antigen-G (sHLA-G). Retrospective analysis of PAPP-A and sHLA-G blood levels in historical samples of 112 GDM and 112 controls, drawn at first trimester, and prospective study in 18 GDM ...
Almog Benny B Sarah Racine IVF Unit , Tel Aviv , Israel - - 2014
Abstract This retrospective matched case control study was conducted to evaluate the effects of poor ovarian response in a group of young women (20-30 years) on embryos quality in controlled ovarian hyperstimulation (COH) for in vitro fertilization. Thirty-nine young patients with poor ovarian response (≤5 oocytes on retrieval) were enrolled ...
Puente Cecilia Peñacoba CP Department of Psychology, Universidad Rey Juan Carlos, Avda de Atenas s/n, 28922, Alcorcón, Madrid, Spain, - - 2014
Most studies about coping in pregnancy focus on risk pregnancies where it has generally been found that the use of religious coping has a positive effect, although to our knowledge there are no studies that associate religious coping to locus of control. We analyzed, in a sample of 285 Spanish ...
Lupo Philip J PJ Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA, - - 2014
Previous assessments of childhood rhabdomyosarcoma have indicated maternal and birth characteristics may be associated with tumor development; however, much work remains to identify novel and confirm suspected risk factors. Our objective was to evaluate the associations between maternal and birth characteristics and childhood rhabdomyosarcoma. This case-control study included 322 cases ...
Vinter Christina Anne CA Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark; University of Southern Denmark, - - 2014
To study the effects of lifestyle intervention in pregnancy on weight retention six months postpartum among obese women from the "Lifestyle in Pregnancy" (LiP)-study, and to determine associations between breastfeeding with postpartum maternal weight. Six months postpartum follow-up after a randomized controlled intervention trial. Two university hospitals in Denmark. 360 ...
Policiano Catarina C Department of Obstetrics and Gynecology, Central Hospital of Lisbon North, Hospital of Santa Maria, Lisbon, Portugal. Electronic address: - - 2014
To evaluate the delivery route and the indications for cesarean delivery after successful external cephalic version (ECV). A retrospective matched case-control study was conducted at a hospital in Lisbon, Portugal, between 2002 and 2012. Each woman who underwent successful ECV (n=44) was compared with the previous and next women who ...
Logan Dustin M DM a Department of Psychology , Brigham Young University , Provo , UT , - - 2014
Current literature on cognitive functioning in pregnancy and postpartum is mixed, with most research showing deficits in memory and attention during pregnancy or no difference between pregnant participants and controls with little emphasis on the postpartum period. In the current study, we used a longitudinal controlled design and 42 primarily ...
Mavrogenis Stelios S National Institute of Oncology, Department of Uro-oncology, Budapest, - - 2014
Abstract Objective. The evaluation of pregnancy complication of mothers who delivered boys with isolated hypospadias (IHS) to estimate their roles in the higher rate of low birthweight and preterm birth in cases with IHS. Methods. The incidence of prospectively and medically recorded pregnancy complications in the prenatal maternity logbook was ...
Hernández-Díaz Sonia S Department of Epidemiology, Harvard School of Public Health, Boston, MA. Electronic address: - - 2014
Maternal use of anticonvulsants during the first trimester of pregnancy has been associated with an elevated risk of major congenital malformations in the offspring. Whether the increased risk is caused by the specific pharmacological mechanisms of certain anticonvulsants, the underlying epilepsy, or common genetic or environmental risk factors shared by ...
Visconti Kevin C KC Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Tennessee Medical Center, Knoxville, - - 2014
Objective The aim of the study is to evaluate whether chronic opiate use in pregnancy affects newborn head circumference (HC). Study Design All newborns from January 1, 2010, to June 30, 2012, admitted to the neonatal intensive care unit for treatment of neonatal abstinence syndrome were prospectively collected. The demographic, obstetrical, neonatal, ...
Boulis Tharwat Stewart TS Hofstra North Shore-LIJ School of Medicine, Manhasset, - - 2014
The objective of this study was to evaluate the association between maternal serum analytes and placenta previa. Chart review of deliveries from 2004 to 2012 with two comparison groups: placenta previa without accreta and a control group. Patients in the control group were randomly selected from deliveries without placenta previa. ...
Liao Can C Prenatal Diagnostic Center, Guangzhou Women & Children Medical Center affiliated to Guangzhou Medical College, Guangzhou, Guangdong, - - 2014
Abstract α-thalassemia is a common inherited disease in southern China. The severest form is Hb Bart's hydrops fetalis, in which the affected fetuses almost always die in utero or shortly after birth, and the mothers are at high risk for severe morbidity. Therefore, this condition should be controlled, especially prenatally. ...
Mavrogenis Stelios S National Institute of Oncology, Department of Uro-oncology, Budapest, - - 2014
The objective of the study was to evaluate the possible association of maternal factors with the risk of isolated true undescended testis (ITUT) diagnosed at third postnatal month because our knowledge is limited regarding the origin of ITUT. Acute and chronic diseases with related drug treatments were compared in the ...
Polat Mehtap M Anatolia IVF and Women Health Center, Ankara, - - 2014
This study is to assess whether transient intrauterine fluid accumulation (IUFA) first noted during controlled ovarian hyperstimulation that does not persist on the day of embryo transfer not due to any identifiable pelvic pathology has any detrimental effect on in vitro fertilization (IVF) outcome. From a database of 16,900 cycles, ...
Davison A Z AZ Early Pregnancy and Gynaecology Assessment Unit, Suite 8, Golden Jubilee Wing, King's College Hospital, Denmark Hill, London SE5 9RS, - - 2014
To establish if women obtain any measurable short term psychological benefit or perceived benefit from having a test to determine the probability of their pregnancy being on-going when this is uncertain on ultrasound examination. This was a prospective randomised controlled study conducted January 2012-June 2012 at the EPU of King's ...
Founds Sandra A SA 1School of Nursing, University of Pittsburgh, Pittsburgh, PA, - - 2014
The purpose of this study was to examine circulating maternal follistatin-like 3 (FSTL-3) by gestational age and obesity in pregnancy and preeclampsia. FSTL-3 was quantified in maternal plasma collected in each trimester from prepregnancy body mass index-determined groups: 15 lean and 24 obese controls and 20 obese women who developed ...
Nooij Linda S - - 2014
Objective: Hypertensive disorders in pregnancy remain a major cause of maternal morbidity and mortality. Blood pressure control is essential for maternal and neonatal outcome. Therefore, we analyzed the potency and side effects of two treatment options (nicardipine compared to labetalol) in order to gain insight in improved treatment of severe ...
Mansour Ghada M GM Department of Obstetrics and Gynecology, Ain shams university, Cairo, - - 2014
Abstract Purpose: To obtain three dimensional power Doppler (3DPD) indices of placenta in pregnancies complicated with preeclampsia compared to normal pregnancies and correlated to umbilical artery Doppler and albuminuria. Methods: A case-control study, was conducted at Ain Shams university maternity hospital. Evaluation of placental vascular indices, vascularization index (VI), flow ...
Eadie Mervyn J MJ University of Queensland, Honorary Consultant Neurologist, School of Medicine and Biomedical Science , 4th Floor, Ladhope Chambers, 131 Wickham Terrace, 4000 Brisbane , Australia +61 7 38311704 ; +61 7 33719886 ; M.Eadie@ - - 2014
Introduction: The management of epilepsy during pregnancy involves achieving the best compromise between the sometimes competing aims of maintaining the well-being of the prospective mother and that of her foetus. Recently available knowledge helps achieve this by providing a better understanding of the hazards that intrauterine exposure to antiepileptic drugs ...
Zainul Rashid M R MR Department of Obstetrics and - - 2014
Abstract Background: Gestational hypertension (GH) remains one of the main causes of high maternal and perinatal morbidity and mortality worldwide with the highest incidence among primigravidae of about 10%-15%. However, it was noted that the incidence of GH in primigravidae who conceived following assisted reproductive technique (ART) or intrauterine insemination ...
Csáky-Szunyogh Melinda - - 2014
The aim of this study was to assess the risk factors in the origin of lethal or surgically corrected isolated atrial septal defect secundum. The population-based Hungarian Case-Control Surveillance of Congenital Abnormalities (conducted between 1980 and 1996) comprised 472 atrial septal defect secundum cases, 678 matched controls and 38,151 available ...
Heo Y T YT Department of Animal Sciences, Chungbuk National University, Cheongju, South - - 2014
There are different methods for cryopreservation of mammalian embryos with variable degrees of success. These methods require specific vessels for embryo vitrification, thawing, and transfer. Here, we report a simple and inexpensive way to vitrify, thaw and transfer mammalian blastocysts in one straw. This in-straw vitrification solution with microdrop (ISVDM) ...
Aye C Y L CY Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, Oxfordshire, United Kingdom. Electronic address: - - 2014
To investigate the effect of syntocinon augmentation on the fetal cardiotocogram (CTG) using computerised analysis. We hypothesised that syntocinon will have no direct effects on the fetal heart rate if used correctly. A retrospective, nested case-control study. Intrapartum CTG records from the digital archive at the John Radcliffe Hospital, Oxford, ...
Warby Ann-Christin - - 2014
Abstract Objective: To determine whether certain rheumatic diseases will affect the fetal thymus diameter when compared to uncomplicated singleton pregnancies. Additionally, we created a reference chart for fetal thymus size in healthy singleton pregnancies from 19 to 37 weeks of gestation. Methods: Sonographic fetal thymus size was retrospectively evaluated in ...
Hönger Gideon G Transplantation Immunology and Nephrology, University Hospital Basel, Basel, - - 2014
Non-HLA antibodies against the angiotensin II type 1 receptor (AT1 R) and the C-terminal fragment of perlecan (i.e., LG3) are associated with the development of renal allograft rejection. It is currently unknown how humans develop anti-AT1 R or anti-LG3 antibodies. The aim of this study was to investigate whether pregnancy-as ...
Jaakkola Johanna J Department of Clinical Sciences, University of Turku, Finland; Functional Foods Forum, University of Turku, - - 2014
As pregnancy may trigger overweight in women, new means for its prevention are being sought. The aim here was to investigate the effect of individual dietary counselling during and after pregnancy on post-partum weight and waist circumference up to 4 years post-partum. A cohort of women (n = 256) were randomized to ...
Hashish N M NM Department of Obstetrics and Gynaecology, Assisted Reproduction Unit, Faculty of Medicine, Cairo University, - - 2014
Follicular fluid of mature oocytes is rich in growth factors and cytokines that may exert paracrine and autocrine effects on implantation. The aim of this study was to investigate if flushing the endometrial cavity with follicular fluid after oocyte retrieval improved pregnancy rates in subfertile women undergoing intracytoplasmic sperm injection ...
Gould Jacqueline F JF Women's and Children's Health Research Institute, Adelaide, Australia (JFG and MM); the Disciplines of Paediatrics (JFG and MM) and Public Health (LGS), the University of Adelaide, Adelaide, Australia; the South Australian Health and Medical Research Institute, Adelaide, Australia (MM); and the Schiefelbusch Institute for Life Span Studies and Department of Psychology, University of Kansas, Lawrence, KS - - 2014
Docosahexaenoic acid (DHA) accumulates in the hippocampus and frontal lobes of the fetal brain during the last trimester of pregnancy. These areas of the brain contribute to attention and working memory and inhibitory control (WMIC). We evaluated the effect of maternal omega-3 (n-3) long-chain polyunsaturated fatty acid supplementation in pregnancy ...
Votava-Smith Jodie K JK Department of Pediatrics, Division of Pediatric Cardiology, Columbia University Medical Center, Morgan Stanley Children's Hospital, New York, NY, - - 2014
We compared the proportion of conception with and without in vitro fertilization (IVF) in fetuses with and without congenital heart disease (CHD). This was a retrospective review of fetal echocardiograms at Columbia University from 2007 to 2010, to identify the mode of conception. Echocardiography was performed on 2828 fetuses, and ...
Blais Lucie L Faculty of Pharmacy, Université de Montréal, Montréal, Québec, - - 2014
Abstract Objectives: To assess the associations of maternal asthma severity and control with pregnancy-induced hypertension (PIH), gestational diabetes, and cesarean delivery. Methods: A cohort of 41,660 pregnancies from women with and without asthma who delivered between 1990 and 2002 was constructed by linking Québec's administrative databases. Maternal asthma was defined ...
Feuermann Yonatan Y Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of - - 2014
Development of mammary alveolar epithelium during pregnancy is controlled by prolactin, through the transcription factors STAT5A/B that activate specific sets of target genes. Here we asked whether some of STAT5's functions are mediated by microRNAs. The miR-21 promoter sequence contains a bona-fide STAT5 binding site and miR-21 levels increased in ...
Sklavos Martha M MM Human Papillomavirus Immunology Laboratory, Leidos Biomedical Research, Incorporated, Frederick National Laboratory for Cancer Research, Building 469, Room 111, 1050 Boyles Street, Frederick, MD 21702, - - 2014
Background. A delayed time to pregnancy was recently reported for women who had a loop electrosurgical excision procedure (LEEP) to remove cervical intraepithelial neoplasia (CIN) grade 2 or 3. The objective of the current study was to determine if treatment of CIN with LEEP is associated with decreased levels of ...
Grieger Jessica A - - 2014
Asthma is the most prevalent chronic disease to complicate pregnancies worldwide, affecting around 12% of pregnant women in Australia. Oxidative stress and inflammation manifest during pregnancy; however asthma in pregnancies further intensifies oxidative stress. Consumption of antioxidant-rich foods has been shown to be beneficial for asthma control in non-pregnant asthmatic ...
Eszes Noémi N Department of Pulmonology, Semmelweis University, Budapest, - - 2014
Uncontrolled asthma is a risk factor for pregnancy-related complications. Hyaluronic acid (HA), a potential peripheral blood marker of tissue fibrosis in various diseases, promotes eosinophil survival and plays a role in asthmatic airway inflammation as well as in physiological processes necessary to maintain normal pregnancy; however the level of circulating ...
Zha J - - 2014
The current study aims to establish reference ranges for thyroid hormones in normal pregnant women during their pregnancy period. A one-time cross-sectional survey was conducted on 490 normal pregnant women and 51 nonpregnant women (control). The serum thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free tetraiodothyronine (FT4) levels were ...
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