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Wright A - - 1998
The results of a postal questionnaire survey conducted between December 1992 and March 1993 indicated that a third of mated female South American camelids in the United Kingdom failed to produce offspring. This failure did not include abortions or stillbirths, which accounted for up to 4 per cent and up ...
McLean K A - - 1998
Maternal oestrogen and progesterone have been shown to be important in the initiation of maternal behaviour. Thirty-three Large White x Landrace gilts, housed in groups during pregnancy, were observed and aggressive interactions recorded. Individuals had jugular catheters implanted 14.5 (s.e. 0.34) days before their expected parturition date (EPD). Five days ...
Hambartsoumian E - - 1998
The expression of leukemia inhibitory factor (LIF) by murine uterus was shown to be regulated by maternal hormones and was not dependent on the presence of an embryo. The objective of this study was to investigate whether in humans the secretion of LIF during early pregnancy is under maternal control ...
Chang F Y - - 1998
We investigated whether various periods of pregnancy might disturb rat gastrointestinal motility. When the proestrus of female rats occurred, they were housed with male rats. Motility studies were conducted on day 7 (first period), day 14 (second) and day 21 (third) of pregnancy, respectively. After the orogastric feeding of radiochromium ...
Ismail K - - 1998
A 36-year-old female presented with seizures and transient dysphasia in her 31 week of pregnancy. Neuroradiological investigations revealed a large falx meningioma. A decision was taken to deliver the infant and excise the tumor before term because of the risk of an increase in the size of the tumour and ...
Gibbons W E - - 1998
OBJECTIVE: To compare the efficacy of a vaginal progesterone preparation with our standard IM preparation within a donor egg program. DESIGN: Prospective randomized trial. SETTING: Donor egg program at a university assisted reproductive therapy program (Jones Institute for Women's Health). PATIENT(S): Couples accepted into the donor egg program because of ...
Lo Y M YM Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong - - 1998
It is a long-term goal of human genetics to develop prenatal diagnostic tests that are noninvasive and which do not constitute a risk to the mother or fetus. Such tests would be highly desirable compared with current techniques that require the sampling of fetal tissues by invasive measures such as ...
Sekizawa A - - 1998
Prenatal diagnosis of hereditary diseases is usually performed by collecting fetal samples using amniocentesis, chorionic villus sampling (CVS), or cordocentesis. However, these procedures are associated with some degree of risk. For example, abortion owing to hemorrhage or infection occurs in 0.2-0.4% of patients undergoing amniocentesis. Furthermore, CVS reportedly presents the ...
Montoneri C - - 1997
After mating with a sexually active male, groups of female Sprague-Dawley rats were injected with cysteamine (400 mg/kg, subcutaneously) at day 0 (controls), day 5 (early-stage pregnancy), and day 18 (late-stage pregnancy) of pregnancy. In contrast to late-stage pregnancy rats, early-stage pregnancy animals showed a decrease of cysteamine-induced gastroduodenal lesions. ...
Murri L - - 1997
This study was undertaken to determine plasma allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one, A-PREG) and pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one, PREG) concentrations in the luteal phase (22nd to 24th day of the ovarian cycle) in 15 women with partial epilepsy and catamenial exacerbation of the seizures in the intercritical phase and in 15 healthy women matched for ...
Cummings A M - - 1997
Ketoconazole (KCZ) is an imidazole antifungal agent that also affects P450 enzymes of the mammalian steroidogenic system. Several steps in the ovarian steroidogenesis pathway are known to be inhibited by KCZ, but previous work has failed to address the ramifications of such inhibition with respect to early pregnancy. In initial ...
Goh CL - - 1997
This report identifies 4 pregnancy-induced dermatoses: (1) pemphigoid gestationis, (2) polymorphic eruption of pregnancy, (3) prurigo of pregnancy, and (4) pruritic folliculitis of pregnancy. According to 1 study of 3192 pregnancies, 0.06% of the women had pemphigoid gestationis (PG), 0.5% had polymorphic eruption of pregnancy (PEP), 0.2% had prurigo of ...
Weiner C P - - 1997
We have hypothesized that an alteration in the production of endothelium-dependent factors by sex hormones is a potential unifying mechanism for both the decreased arterial contractility and the redistribution of cardiac output characteristic of normal pregnancy. Thus, the effect of pregnancy/ estradiol on any one vascular bed will reflect the ...
Dombroski R A - - 1997
5Alpha-dihydroprogesterone (5alpha-DHP) is the immediate precursor of 5alpha-pregnan-3alpha-ol-20-one, a potent anxiolytic/anesthetic agent in all vertebrate animals tested, including humans. The levels of 5alpha-DHP in the plasma of pregnant women are very high; and during the third trimester of pregnancy, the blood production rate of this steroid may exceed 100 mg/24 ...
Moriyoshi M - - 1997
We attempted to measure the gestagen concentration in the feces of pigs by using a commercial bovine milk progesterone quantitative test EIA kit, and investigated the possibility of applying of this method of gestagen concentration measurement to early pregnancy diagnosis in the sow. Feces were collected from the rectum of ...
Michelin D - - 1997
We examined the in vivo effect of estrogen, progesterone, RU 486, and pregnancy on the upstream regulatory region (URR) of human papillomavirus (HPV) 18 transgenic mice. The mice contain the bacterial reporter beta-galactosidase gene under control of the HPV 18 URR. Pregnant transgenic mice were sacrificed on various days of ...
Bacq Y - - 1997
The aim of this prospective study was to analyze the characteristics of intrahepatic cholestasis of pregnancy (ICP) in a French population. From 1989 to 1995 we studied 50 consecutive pregnant women with ICP (41 single, 7 twin, and 2 triplet pregnancies) referred for hepatologic consultation. All patients suffered from pruritus ...
Hardie L - - 1997
OBJECTIVE: To investigate whether leptin is linked to reproduction, circulating levels were measured longitudinally throughout spontaneous menstrual cycles and during pregnancy in normal women. DESIGN: Longitudinal blood samples were collected from normal volunteers, either during regular menstrual cycles or during successful singleton pregnancies. PATIENTS: Six healthy, regularly cycling, women volunteers ...
Talwar G P - - 1997
PROBLEM: To develop a self-administered, orally delivered method for abrogation of early pregnancy. METHOD: Use of purified Neem extracts containing immunomodulators stimulating Th1 cells and macrophages; test animals, rats, baboons, and monkeys, onset of pregnancy confirmed by surgery and counting of implants on day 7 in rats and by chorionic ...
Engeland I V - - 1997
Two qualitative on-farm milk progesterone test kits were used for early pregnancy diagnosis in goats. One kit was based on latex agglutination (LA) and the other on enzyme-linked immunosorbent assay (ELISA). The accuracy of early pregnancy diagnosis by these two methods was compared with the accuracy of oestrous observation (OeO) ...
Raghupathy R - - 1997
PROBLEM: Does Th1/Th2 balance determine pregnancy outcome, and if so, what determines Th1/Th2 balance in pregnancy? METHOD: Review and synthesis of existing data. RESULTS: A bias toward Th1 is strongly correlated with pregnancy failure in mice and humans. Pregnancy usually shifts the balance toward Th2 and placental factors/progesterone and progesterone-stimulated ...
Check J H - - 1997
PROBLEM: An immunomodulatory protein known as the progesterone induced blocking factor (PIBF) has been found to positively correlate with early pregnancy beta human chorionic gonadotropin (B-hCG) levels. The study presented herein evaluated PIBF levels from conception to the end of the first trimester to determine if lower levels will correlate ...
Fleming A S - - 1997
Two studies were undertaken (1) to determine whether human mothers undergo a change in maternal responsiveness during pregnancy before the birth of the baby, as shown for other mammalian species, and (2) to establish whether a relation exists between changes in maternal feelings and attitudes and changes in hormones. In ...
Ricoul M - - 1997
It was necessary to consider the risks of exposure of pregnant women, not only in relation to the child, but also in relation to their own hypersensitivity. We have demonstrated that pregnancy increases radiosensitivity of chromosome in the mouse at the end of gestation. This is of importance since it ...
Rao B R - - 1997
Seventeen alpha hydroxyprogesterone (17-OHP, is an anti-angiogenic steroid. The existence of a significant negative correlation between the levels of 17-OHP and the appearance of highly vascularized brain and spinal tumours seen during pregnancy is described. However, glioma appears to be an exception to this rule. This exception may be due ...
Milligan S R - - 1997
A study of the degree of progesterone support required for the maintenance of various stages of pregnancy was undertaken in mice. Mated females were ovariectomized at various stages of pregnancy and progesterone and oestradiol support provided by s.c. Silastic implants with known release characteristics. In the earliest stages of pregnancy ...
Haluska G J - - 1997
OBJECTIVES: Uterine quiescence during mammalian pregnancy is attributed to progesterone. However. systemic progesterone levels remain elevated in primates before parturition. Epostane, a selective 3beta-hydroxysteroid dehydrogenase inhibitor, and progesterone (with or without epostane) were administered to late pregnant rhesus monkeys to clarify the role of progesterone in primate parturition. STUDY DESIGN: ...
Aqarwal S P - - 1997
Sixteen anestrous adult female camels (Camelus dromedarius ) in good health and with inactive ovaries were selected from the herd during the month of June (non-breeding season). The camels were randomly divided into 4 equal groups. To induce ovarian activity, camels in Groups I,II and III were given an intramuscular ...
Crossley K J - - 1997
The high rate of progesterone synthesis by the placenta in late gestation exposes the ovine fetus to high concentrations of progesterone and its metabolites that may affect activity of the fetal brain. The aim of this study was to determine the effect of inhibiting maternal progesterone synthesis on sleep-wake activity ...
Hojo M - - 1997
Calcium homeostasis is an important aspect of maternal and fetal physiology during gestation, since fetal bone mineralization requires adaptive adjustments in maternal calcium regulation. In the third trimester, for example, calcium is deposited in the fetal skeleton at the rate of 200mg/day. In addition, women double their urinary excretion of ...
Cabrera R J - - 1996
The proposed modulatory role of progesterone on dopaminergic nerve terminal activity in the striatum was examined in pregnant rats. Endogenous dopamine concentration and the in vitro effect of exogenous progesterone in association with N-methyl-D-aspartic acid (NMDA) upon [3H]dopamine release from striatal slices were determined. Striatal dopamine and 3,4-dihidroxyphenylacetic acid (Dopac) ...
Engeland I V - - 1996
The effect of Toxoplasma gondii inoculation on pregnancy and on endocrine foetal-placental function in pregnant goats was studied. Five susceptible goats were inoculated subcutaneously with T. gondii bradyzoites at 71 +/- 2 days of gestation. Another five goats were used as controls. Plasma was analysed for progesterone, oestrone sulphate and ...
Veress G - - 1996
The high level of progesterone during pregnancy may enhance the transcription and replication of genital human papillomaviruses (HPV) through the glucocorticoid/progesterone response element found in the long control region of the viral genome. In this study, cytologically and colposcopically healthy pregnant women were subjected to a follow-up examination. Samples from ...
Miller K F - - 1996
PURPOSE: Our purpose was to determine if the progesterone concentration on the day of HCG administration is associated with the establishment of pregnancy in IVF patients. METHODS: Concentrations of progesterone on the day of hCG were examined retrospectively in 293 patients with ovarian hyperstimulation induced by GnRH agonist with hMG ...
Salomon R - - 1996
We previously reported that lactose handling was significantly improved during late-phase pregnancy in women with a genetically determined adult-type hypolactasia. However, the adaptive mechanisms underlying the enhanced lactose digestion during pregnancy are not clear. Progesterone therapy has been associated in animals with increased intestinal lactase activity. To investigate the potential ...
Zhang X - - 1996
In the mouse, estrogen and progesterone are required to prime the uterus for decidual cell reaction (DCR) in response to an intraluminal stimulus and, once DCR is induced, progesterone is required to maintain DCR. However, some evidence indicates that certain nonprogestational steroid hormones may also be involved in regulating DCR. ...
Mavrelos K - - 1996
Twelve women underwent laparoscopic removal of benign ovarian cysts during pregnancy. Gestational age at the time of surgery ranged from 12 to 20 weeks (mean 15 wks). Cyst size ranged from 6 to 9 cm (mean 7.1 cm). In all 12 patients a cystectomy was performed. Estimated blood loss ranged ...
Mochtar M H - - 1996
Two different regimens of luteal support in gonadotrophin hormone-releasing hormone (GnRH) analogue/human menopausal gonadotrophin (GnRHa/HMG)-induced in-vitro fertilization cycle (IVF) were compared in a randomized clinical trial. After embryo transfer, either vaginal progesterone alone was administered (n = 89, P group), or a combination of vaginal progesterone and human chorionic gonadotrophin ...
Deprest JA - - 1996
Laser coagulation of anastomosing placental chorionic plate vessels was suggested as a treatment of severe twin-twin transfusion syndrome in midtrimester. An anteriorly located placenta may hamper access and visualization of the vessels involved. We treated six women with completely anterior placenta at 18 to 22 weeks' gestation. Through a 2- ...
Batt RE - - 1996
In this prospective cohort study, 30 women diagnosed at laparoscopy with mild endometriosis were treated expectantly and followed for 10 years. Eleven women had primary infertility and 19 secondary infertility. Before the diagnosis of endometriosis, 19 women had a total of 32 pregnancies: the female live birth rate was 25%, ...
Gassibe EF - - 1996
During laparoscopy for a ruptured ectopic tubal pregnancy, two gestational sacs with the embryos were found free in the pelvis. The patient did not have ovulation-induction treatment. A triple-loop salpingectomy was performed. The woman's postoperative course was uneventful. Studies to diagnose monozygocity or dizygocity were not performed.
Moriyoshi M - - 1996
We attempted to measure the qualitative saliva progesterone concentration in the sow using a commercial bovine milk progesterone qualitative test EIA kit (qualitative kit), which can measure the progesterone concentration in approximately 10 min, and investigated the possibility of applying this method of progesterone concentration measurement to early pregnancy diagnosis ...
Roemisch M - - 1996
We evaluated the safety of laparoscopic myomectomy in 114 women (average age 37.1 yrs, mean 34.1 &plusmn; 3.6 yrs) who desired future pregnancy. The indications were pain (77.8%), abnormal bleeding (53.1%), and infertility (20.8%). Follow-up data were obtained by reviewing patient charts or returned questionnaires. Student's nonpaired two-way t test ...
García-Rio F - - 1996
STUDY OBJECTIVE: To examine if the perception of dyspnea during normal pregnancy may be related to an inappropriate ventilatory response to the increased metabolic rate, due to a higher chemosensitivity. PATIENTS AND INTERVENTIONS: At weeks 12, 24, and 36 of gestation and 4 months after delivery, 11 healthy pregnant women ...
Yang B - - 1996
AIM: To clarify the role of DL111-IT when combined with mifepristone (Mif) on termination of early pregnancy. METHODS: Progesterone receptors (PR) was measured using radioligand assay (RA), and peroxidase-antiperoxidase (PAP) immuno-histochemistry. Decidual cells (DC) were estimated using cell culture and histological examination (HE) (including fetus). RESULTS: DL111-IT 100 mg.kg-1 i.m., ...
- - 1996
Second-trimester screening of a pregnant woman's serum for markers of such congenital abnormalities as fetal trisomy 21 (Down syndrome) and neural tube defects has become an important part of antenatal care. The protocol most commonly used is the triple marker screen, which measures serum levels of alpha-fetoprotein (AFP), unconjugated estriol ...
Nowak M - - 1996
A study on the release of 17 beta-estradiol and progesterone from d,l-lactide and epsilon-caprolactone copolymer was performed. The copolymer was used in the form of microsphere, d,l-lactide content in the copolymer was 83%. It was found that nearly constant rate of hormone release during 100 days of experiment can be ...
Mukherjee S - - 1996
The use of neem (Azadirachta indica) seed extracts (Praneem) given orally for abrogation of pregnancy in subhuman primates is described. Oral administration of Praneem was initiated after confirmation of pregnancy using Leydig cell bioassay estimating rising levels of chorionic gonadotropin (CG) in the blood from day 25 onwards of the ...
Chiu L - - 1996
PROBLEM: The immunological mechanism of an effective immunotherapy with paternal lymphocytes for unexplained recurrent spontaneous abortion (RSA) is not yet clear. Previous studies revealed that progesterone plays an important role in maintaining normal pregnancy and lower expression of progesterone receptor (PGR) on lymphocytes was found in RSA. Therefore, it was ...
Kelly R W - - 1996
A role for inflammatory mechanisms in ovulation and parturition has been proposed on many occasions. In addition, many agents directly implicated in parturition, such as cytokines and prostaglandins, can be pro-inflammatory. The cervix can be softened and labour induced in women by mechanical trauma (sweeping the membranes), prostaglandins, antiprogestins or ...
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