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Galindo Alberto - - 2010
Introduction: Second-trimester fetal screening for congenital heart defects (CHD) included in routine obstetric care provides relevant information for decision making. The aim of this study was to describe the clinical practice of prenatal detection of CHD in terms of the process and results. Methods: The characteristics and results of ultrasound ...
Sarfraz Aa - - 2010
Please cite this paper as: Sarfraz A, Samuelsen S, Eskild A. Changes in fetal death during 40 years-different trends for different gestational ages: a population-based study in Norway. BJOG 2010; DOI: 10.1111/j.1471-0528.2010.02819.x. Objective  To study changes in gestational-age-specific fetal death risks during a 40-year period. Design  Register-based observational study. Setting  The ...
Sipsma Heather L HL Yale University School of Public Health, and Yale Center for Interdisciplinary Research on AIDS, 60 College Street, New Haven, CT 06510, USA. - - 2011
Research has suggested the importance of pregnancy desire in explaining pregnancy risk behavior among adolescent females. Much of the literature, however, uses cross-sectional study designs to examine this relationship. Because bias may strongly influence these results, more prospective studies are needed to confirm the relationship between pregnancy desire and pregnancy ...
Pagnoux Christian - - 2010
Objectives. To describe pregnancies of women with systemic necrotizing vasculitides (SNVs), i.e. PAN, WG, Churg-Strauss syndrome (CSS) or microscopic polyangiitis (MPA), followed over the past 15 years at four French centres. Methods. Retrospective analysis of women whose SNV appeared during pregnancy or who became pregnant after SNV diagnosis. Results. Among ...
Evans Patricia - - 2011
We have investigated factors affecting iron distribution in the first-trimester gestational sac, by the measurement of transferrin, non-transferrin-bound iron (NTBI) and pro-hepcidin (Hep) in maternal serum, coelomic fluid (CF) and amniotic fluid (AF) and by immunostaining for Hep in villous and secondary yolk sac biopsies. These samples were obtained from ...
Guimaraes Carolina V A - - 2010
BACKGROUND: Twin reversed arterial perfusion sequence (TRAP) is a rare complication in multifetal monochorionic pregnancies in which a normal "pump" twin provides circulation to an abnormal acardiac co-twin, resulting in high-output cardiac dysfunction in the pump twin. OBJECTIVE: To define fetal MRI findings of TRAP sequence. MATERIALS AND METHODS: Fetal ...
Gedikbasi Ali A Istanbul Bakirkoy Maternity and Children Diseases Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey. - - 2011
Mirror syndrome (Ballantyne's syndrome) refers to the association of fetal hydrops and maternal preeclampsia. The aim of this study was to determine the relation and incidence between fetal hydrops and preeclampsia in our clinic. A retrospective review of patients associated with fetal hydrops and findings with preeclampsia was used. Seventy-five ...
Madi José M JM Obstetric and Gynecology Department, Hospital Geral, Caxias do Sul University, Caxias do Sul, RS, Brazil. - - 2012
Analyze maternal and perinatal aspects related to chronic hypertension (CH) in pregnancy. Cross-section and retrospective study. Maternal, obstetric, and neonatal variables inserted in a database of the SPSS program, version 16.0, were analyzed. Student's t-test was applied to the continuous variables and the chi-square test to the dichotomous variables, considering ...
Marchaudon V - - 2010
INTRODUCTION: Chronic histiocytic intervillositis of unknown etiology (CIUE) is a rare placental inflammatory disease, associated with severe obstetric complications. Its pathophysiologic mechanism remains to be elucidated. AIM: To establish anatomical-clinical correlations to improve our understanding of CIUE pathophysiology. MATERIAL AND METHODS: Retrospective study of all cases of CIUE occurring during ...
Vedmedovska Natalija - - 2010
OBJECTIVES: One of the causes of intrauterine fetal growth restriction (FGR) can be pathology of the placenta. The aim of this study was to compare macroscopic and microscopic changes of the placentas from intrauterine growth restricted fetuses with those from normally developed fetuses, in order to test the hypothesis that ...
Gibson Catherine S - - 2010
Objective. To investigate the roles of inherited polymorphisms in the MBL2 gene and exposure to viral infection in the development of a range of adverse pregnancy outcomes, including birthweight <10th percentile (small-for-gestational age, SGA), antepartum hemorrhage (APH), pregnancy-induced hypertensive disorders (PIHD), and preterm birth (PTB). Methods. This was a case-control study using DNA ...
Rusterholz Corinne C Laboratory for Prenatal Medicine, Department of Biomedicine, University Hospital Basel, Basel, Switzerland. - - 2011
Preeclampsia is a common disorder of the second half of pregnancy that complicates 2% to 7% of all pregnancies worldwide and remains a major cause of maternal and fetal morbidity and mortality. Although the origin of the disease is still elusive, population-based studies have suggested that it might implicate genetic, ...
Nama Vivek - - 2010
BACKGROUND: Current dogma states that there is a mid-trimester fall in blood pressure (BP) in uncomplicated pregnancy. In the early stages of a longitudinal study of microcirculatory changes in pregnancy, we noted an absence of this mid-trimester fall. METHOD: We prospectively studied this phenomenon in all our subsequent recruits. From ...
Paglia Michael J - - 2010
PURPOSE OF REVIEW: Gestational diabetes mellitus (GDM) is a common complication of pregnancy. There has been controversy and debate about how to optimally diagnose GDM and whether treatment modifies outcomes. We review the current controversies in both the screening and diagnosis of GDM and the benefits of treating GDM. RECENT ...
Burdorf A - - 2010
Objective To investigate the influence of maternal working conditions on fertility and pregnancy outcomes. Methods 8880 women were enrolled in a large prospective birth cohort during early (76%), mid (21%) or late pregnancy (3%) (61% participation). Complete questionnaire information was available for 6302 women (71% response). Outcomes were prolonged time ...
Bourjeily Ghada - - 2011
Symptoms of sleep-disordered breathing are more common in pregnant women compared with nonpregnant women. It is likely that physiology of pregnancy predisposes to the development or worsening of sleep-disordered breathing, but some physiologic changes may also be protective against the development of this disease. Clinical presentation may be less predictive ...
Schmid Seraina M - - 2010
INTRODUCTION: In the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While the symptoms are unresponsive to antiemetic ...
Brito Veronica - - 2011
Community-acquired pneumonia (CAP) can affect pregnancy, posing risks to mother and fetus. CAP is the most common fatal nonobstetric infectious complication and a common cause of hospital readmission. Risk factors of pneumonia in pregnancy relate to anatomic and physiologic respiratory changes and immune changes. Aspiration can occur during labor, can ...
Murphy Vanessa E - - 2011
Worldwide the prevalence of asthma among pregnant women is on the rise, and pregnancy leads to a worsening of asthma for many women. This article examines the changes in asthma that may occur during pregnancy, with particular reference to asthma exacerbations. Asthma affects not only the mother but the baby ...
Zhang S - - 2010
Women entering pregnancy with a high body weight and fat mass have babies at increased risk of becoming overweight or obese in childhood and later life. It is not known, whether exposure to a high level of maternal nutrition before pregnancy and exposure to a high transplacental nutrient supply in ...
Spada Eva - - 2011
Canine leishmaniasis during pregnancy is rarely reported, even in countries where the infection in dogs is endemic. The authors report a case of a 4 yr old bitch with leishmaniasis treated with meglumine antimoniate during pregnancy. The pregnancy and delivery were normal and the bitch presented improvement of the infection ...
Brandes M - - 2011
BACKGROUND Unexplained infertility is one of the most common diagnoses in fertility care. The aim of this study was to evaluate the outcome of current fertility management in unexplained infertility. METHODS In an observational, longitudinal, multicentre cohort study, 437 couples were diagnosed with unexplained infertility and were available for analysis. ...
Park Jung H - - 2011
To compare socioeconomic status and pregnancy outcomes in relation to different pre-pregnancy body mass index (BMI) levels, and to determine whether gestational weight gain is related to socioeconomic status and pregnancy outcomes. This was a retrospective cohort study of 3554 singleton pregnancies. Gravidas were grouped into three BMI categories and ...
Bliddal Sofie - - 2011
Treatment of Graves' disease during pregnancy with antithyroid drugs (ATDs) poses a risk of inducing hypothyroidism and, thus, development of a goiter to the fetus. We report two patients referred to our department after discovery of a fetal goiter by ultrasound examination in the second trimester of pregnancy. The women ...
Gyimadu Adam O - - 2011
Retroperitoneal hemorrhage following ruptured renal angiomyolipoma is usually managed surgically or by embolization. But when the same episode occurs in pregnancy, surgery which predisposes to preterm delivery and its subsequent sequelae, the unknown influences of radiation exposure on the fetus makes the management of such cases very challenging. A 21-year-old ...
McClure Candace K CK Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. - - 2011
There is growing interest in the relationship between gestational weight gain (GWG) and long-term maternal and child outcomes, yet little is known about the accuracy of long-term maternal recall of GWG. Our objective was to assess the accuracy of maternal recall of GWG at 4-12 years postpartum (mean, 8 years) ...
Vitoratos Nikolaos - - 2011
To investigate changes in maternal serum resistin levels during pregnancy and postpartum and clarify their relationship to insulin resistance. Thirty normal pregnant women were compared to 30 women diagnosed with gestational diabetes mellitus (GDM). Serum resistin levels were collected at the time of glucose challenge test (26-28 weeks), at 38 ...
Luewan Suchaya - - 2010
Impetigo herpetiformis is a rare disease and its occurrence is specific for pregnancy. The lesions are characterized by sterile, pustular eruptions. The disorder is usually seen in the third trimester, but cases of impetigo herpetiformis appearing in the first trimester have also been reported. The lesions are expected to disappear ...
Wranning Caiza A - - 2010
BACKGROUND Uterus transplantation (UTx) research aims towards the introduction of UTx as a treatment for uterine factor infertility. The rat model is the principal rodent model used and this study aims to assess the potential for pregnancy and to assess effects on pregnancy outcome. METHODS Female Lewis rats underwent hysterectomy ...
Lindehammer Sabina Resic - - 2011
Islet autoantibodies are currently used to classify type 1 diabetes at diagnosis as they reflect the autoimmune pathogenesis of the disease. The presence of maternal autoantibodies reactive with pancreatic islet antigens is thought to increase the risk for type 1 diabetes in the offspring. The objective of this study was ...
Koshy Gibby - - 2011
ADHD prevalence has risen in parallel with rising prevalence of pregnancy smoking and childhood obesity. The objective was to determine the epidemiological association of pregnancy smoking and childhood obesity with ADHD. A cross-sectional community study was conducted in 2006 using a parental questionnaire. A total of 1,074 schoolchildren aged 5-11 years ...
Didenco Svetlana - - 2011
The transfer of vitamin E across the placenta is limited, but no data exist on the concentrations of vitamin E metabolites carboxyethyl hydroxychromans (α- and γ-CEHCs) in the fetal circulation. We measured α- and γ-CEHC concentrations in maternal and umbilical cord blood pairs and examined their relations to circulating vitamin ...
Boers K E - - 2011
Small for gestational age (SGA) is associated with increased neonatal morbidity and mortality. At present, evidence on whether these pregnancies should be managed expectantly or by induction is lacking. To get insight in current policy we analysed data of the National Dutch Perinatal Registry (PRN). We used data of all ...
Alfaraj M A - - 2011
To compare perinatal and infant surgical outcomes in fetuses with gastroschisis with and without gastric dilation in a single-center cohort. This was a retrospective study of all singleton pregnancies with a prenatal diagnosis of gastroschisis managed at University of Toronto perinatal centers between January 2001 and February 2010. Digital prenatal ...
Ognjanovic S - - 2011
Infant leukaemia is likely initiated in utero. We examined whether analgesic use during pregnancy was associated with risk by completing telephone interviews of the mothers of 441 infant leukaemia cases and 323 frequency-matched controls, using unconditional logistic regression. With the exception of a reduced risk for infant acute myeloid leukaemias ...
Freeman Hugh-James HJ Department of Medicine (Gastroenterology), University of British Columbia Hospital, 2211 Wesbrook Mall, Vancouver, BC V6T1W5, Canada. - - 2010
Celiac disease is a mucosal disorder of the small intestine that may be triggered by dietary exposure to gluten in genetically-susceptible individuals. The disorder is often associated with diarrhea, malabsorption and weight loss along with other extra-intestinal complications. Reproductive changes have been described, including impaired fertility and adverse pregnancy outcomes ...
Kelleher Meredith Anne - - 2010
Progesterone and its neuroactive metabolite, allopregnanolone, are present in high concentrations during pregnancy, but drop significantly following birth. Allopregnanolone influences fetal arousal and enhances cognitive and behavioural recovery following traumatic brain injury. Inhibition of allopregnanolone synthesis increases cell death in fetal animal brains with experimental hypoxia. We hypothesised that complications ...
Jakovski Zlatko - - 2011
Proving incest from tissue obtained by abortion early in pregnancy can be a challenge. Problems include the small quantity of embryonic tissue in the products of conception, and the mixing of DNA from mother and embryo. In many cases, this amorphous material cannot be grossly segregated into maternal and fetal ...
Nigro Giovanni - - 2010
PURPOSE OF REVIEW: To review current prenatal diagnosis and management of congenital cytomegalovirus (CMV) infections with emphasis on maternal screening and available interventions. RECENT FINDINGS: Recent findings include an enhanced understanding of the epidemiology, pathogenesis, and treatment of CMV infections; a knowledge of high-risk women particularly those with chronic exposure ...
Silva Sara - - 2010
Abstract Although popularly designated as "identical", monozygotic (MZ) twins are rarely identical. Much has been speculated on the origin of MZ twins and several theories have been proposed. Post-fertilization events, such as chromosomal mosaicism, skewed X-inactivation and imprinting mechanisms, as well as other epigenetic mechanisms are responsible for the differences ...
- - 2011
Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies, characterized by the development of unbalanced chronic blood transfer from one twin, defined as donor twin, to the other, defined as recipient, through placental anastomoses. If left untreated, TTTS is associated with very high perinatal mortality and ...
Deka Deepika - - 2010
BACKGROUND: Rupture of the uterus, especially in a scarred uterus, intrapartum is well known. The risk of uterine rupture in women with a previous lower segment caesarean section is 0.2-1.5%, whereas in an unscarred uterus it is extremely rare. CASE: Case 1 A 26-year-old woman in her third pregnancy was ...
Gorgal Rosário - - 2010
Objective: To evaluate the contribution of prenatal and postmortem examinations in establishing the aetiology of acrania. Methods: Retrospective evaluation of 14 cases of acrania managed through elective termination of pregnancy. Results: The median maternal age was 30 years (range 18-40) and median gestational age at diagnosis was 13 weeks (range ...
Marzena Laskowska - - 2010
Objective. The aim of this study was to evaluate maternal asymmetric dimethylarginine (ADMA) levels in pregnancies complicated by isolated fetal intrauterine growth restriction (IUGR), in preeclamptic pregnancies with and without IUGR, and in healthy normotensive pregnant women with proper weight fetuses. Patients and methods. The study was carried out on 54 normotensive ...
Nold Christopher - - 2010
Objective. To evaluate the optimal time for delivery in singleton pregnancies with preterm premature rupture of membranes (PPROM) when delivered between 32 and 36 6/7 weeks gestational age (GA). Study design. We performed a retrospective cohort study of all singleton pregnancies with PPROM who delivered between 32 and 36 6/7 weeks gestation ...
Talic Amira - - 2010
Objective. To assess differences of fetal behavior in normal and high-risk pregnancies. Methods. In the 1-year period (1 January 2007-31 December 2007), four-dimensional ultrasound has been used to assess Kurjak antenatal neurodevelopmental test (KANET) in low- and high-risk pregnancies after randomization in prospective longitudinal cohort study. Based on the KANET scores, the ...
Castorino Kristin - - 2011
The treatment of diabetes in pregnancy has potentially far-reaching benefits for both pregnant women with diabetes and their children and may provide a cost-effective approach to the prevention of obesity, type 2 diabetes mellitus, and metabolic syndrome. Early and accurate diagnosis of diabetes in pregnancy is necessary for optimizing maternal ...
Yu Zhangbin - - 2010
Congenital heart defects (CHD) are the most common form of major birth defect, affecting almost 1% of live births. These defects place a significant economic burden on the National Health Service and on the psychological wellbeing of affected families. The early screening and identification of neonates with CHD could reduce ...
Khresheh Reham - - 2010
OBJECTIVE: to explore the strategies used by Jordanian women to manage heartburn during pregnancy. DESIGN: an exploratory descriptive study. PARTICIPANTS AND SETTING: 235 Jordanian women from the three regions of Jordan, aged between 18 and 54 years, who were pregnant at the time of the study or had previously had ...
Tamási Lilla - - 2011
Asthma is one of the most common diseases complicating pregnancy and a risk factor for several maternal and fetal complications, posing a special challenge for physicians treating asthmatic pregnant women. Asthma influences the outcome of pregnancy and - vice versa - pregnancy affects asthma severity with bidirectional immunological interactions that ...
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