Search Results
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Bertrand Gerald - - 2011
Fetal/neonatal alloimmune thrombocytopenia is the most common cause of severe thrombocytopenia in the fetus and in an otherwise healthy newborn. To counter the consequences of severe fetal thrombocytopenia, antenatal therapies have been implemented. Predictive parameters for fetal severe thrombocytopenia are important for the development of noninvasive strategy and tailored intervention. ...
Cripe Swee May SM Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195-7236, USA. - - 2011
We evaluated the risks of preterm delivery and hypertensive disorders of pregnancy among pregnant women with mood and migraine disorders, using a cohort study of 3432 pregnant women. Maternal pre-pregnancy or early pregnancy (<20 weeks gestation) mood disorder and pre-pregnancy migraine diagnoses were ascertained from interview and medical record review. ...
Kuleva M - - 2011
OBJECTIVE: To investigate maternal cardiac function in a cohort of uncomplicated twin gestations assessed at different intervals of pregnancy. METHODS: Women with twin pregnancy were prospectively enrolled and submitted to serial maternal echocardiography (20-23 weeks; 26-29 weeks and 30-33 weeks). Patients were eventually removed if any of these complications occurred ...
Durmuş Büşra - - 2011
Maternal smoking during pregnancy increases the risk of obesity in the offspring. Not much is known about the associations with other measures of body composition. We assessed the associations of maternal smoking during pregnancy with the development of subcutaneous fat mass measured as peripheral and central skinfold thickness measurements in ...
Belics Zoran - - 2011
OBJECTIVES: The aim of this study was to present our results of the sonographic measurement of the fetal iliac angle during the first and second trimesters of pregnancy. METHODS: A total of 2168 fetal iliac angle measurements were performed in a transverse section of the fetal pelvis. The iliac angle ...
Belics Zoran - - 2011
The aim of this study was to present our results of the sonographic measurement of the fetal iliac angle during the first and second trimesters of pregnancy. A total of 2168 fetal iliac angle measurements were performed in a transverse section of the fetal pelvis. The iliac angle measurements were ...
Kupferminc Michael J - - 2011
Objectives. The aim of this study was to investigate the effect of low molecular weight heparin (LMWH) on incidence of adverse outcome in women with thrombophilias and previous severe pregnancy complications. Materials and methods. The study included 116 women with history of severe preeclampsia, fetal growth restriction (FGR) ≤5th percentile, severe placental abruption ...
Edlow Andrea G - - 2011
OBJECTIVE: To assess karyotypes and outcomes of monochorionic diamniotic (MCDA) twin pregnancies discordant for markedly enlarged nuchal translucency (NT) in the first trimester. METHOD: Brigham and Women's Hospital's ultrasound database was queried to identify all MCDA gestations in which one twin had NT ≥ 3.5 mm and the co-twin had ...
Deveer Rüya - - 2011
Objective. We aimed to investigate possible alterations in circulating levels of the high sensitivity (hs)-C-reactive protein (CRP) reflecting tissue inflammation in patients who conceived with an intrauterine device (IUD) and in pregnancies after IUD removal in early pregnancy. Methods. Serum hs-CRP levels were measured in 30 pregnant women with retained IUD and ...
Ocer Fahri - - 2011
Objective. To determine the factors affecting the accuracy of ultrasonographic weight estimation in twins. Methods. 152 sets of twins delivered vaginally, were included. Effects of fetal weights, inter-twin weight discordance, chorionicity, early rupture of membranes, intrauterine growth restriction, and presentations of twins on errors of estimated fetal weights were evaluated. The primary ...
Rizzo Giuseppe - - 2011
Objective. The aim of this study was to evaluate the feasibility to visualize central nervous system (CNS) diagnostic planes from three-dimensional (3D) brain volumes obtained in ultrasound facilities with no specific experience in fetal neurosonography. Methods. Five sonographers prospectively recorded transabdominal 3D CNS volumes starting from an axial approach on 500 consecutive ...
Al-Khan A - - 2011
Workshops are an important part of the IFPA annual meeting. At IFPA Meeting 2010 diverse topics were discussed in twelve themed workshops, six of which are summarized in this report. 1. The placental pathology workshop focused on clinical correlates of placenta accreta/percreta. 2. Mechanisms of regulation of trophoblast invasion and ...
Iñiguez Carmen - - 2011
Background In utero tobacco exposure has been associated with adverse pregnancy outcomes but few studies have used longitudinal ultrasound measurements to asses the effects on fetal growth. The aim of this study was to examine the impact of active and passive smoking during pregnancy on fetal biometry in a cohort ...
Porta M - - 2011
The teratogenic consequences of angiotensin-converting enzyme inhibitors angiotensin receptor blockers (ARBs) during the second and third trimesters of pregnancy are well described. However, the consequences of exposure during the first trimester are unclear, especially in diabetes. We report the experience from DIRECT (DIabetic REtinopathy and Candesartan Trials), three placebo-controlled studies ...
Bäumler Marcel Andreas - - 2011
OBJECTIVE:: The aim of this study was to investigate the accuracy of the prenatal axial three-dimensional ultrasound method in predicting the absence or presence of cleft palate when there is cleft lip. METHODS:: 81 cases with a prenatal 2D screening diagnosis of unilateral or bilateral cleft lip at 22-25 weeks ...
Persico Nicola - - 2011
OBJECTIVE:: To assess the accuracy of fetal echocardiography at 11-13 weeks performed by a well-trained obstetrician using a high frequency linear ultrasound transducer. METHODS:: Fetal echocardiography was performed by obstetricians immediately before chorionic villous sampling for fetal karyotyping at 11-13 weeks. Digital video clips of the examination stored by the ...
Saini Vandana - - 2011
BACKGROUND: Recurrent pregnancy loss (RPL) is defined as the occurrence of three or more consecutive miscarriages prior to 20weeks gestation. Exaggerated maternal immune response to fetal antigens has been proposed to be one of the mechanisms underlying recurrent pregnancy loss. METHOD: A comprehensive literature search was conducted from the websites ...
Ronco Ana Maria - - 2011
Several cardiovascular diseases (CVD) observed in adulthood have been associated with environmental influences during fetal growth. Here, we show that maternal exposure to cadmium, a ubiquitously distributed heavy metal and main component of cigarette smoke is able to induce cardiovascular morpho-functional changes in the offspring at adult age. Heart morphology ...
Drabble Laurie A - - 2011
Conceptualizations of risks related to women's alcohol use during pregnancy, and the attendant response to preventing fetal alcohol spectrum disorder (FASD), are examined in six countries: the United States, Canada, the United Kingdom, Uganda, Uruguay, and China. Considerable differences were found in how risks were conceptualized across countries and in ...
Handisurya Ammon - - 2011
Abstract Objective: To assess differences in congenital anomalies, infant mortality, and obstetrical complications as well as risk factors associated with an adverse pregnancy outcome in women with type 1 (T1DM) and type 2 diabetes mellitus (T2DM). Methods: This observational study was performed at a university clinic and included a total ...
Folic Marko M MM Pharmacology Department, Medical Faculty, University of Kragujevac, Kragujevac, - - 2012
Investigation of methyldopa and nifedipine effects on maternal and fetal hemodynamics in women with mild gestational hypertension during the third pregnancy trimester. A prospective cohort study. Methyldopa effects were followed in 28 patients, and nifedipine effects in another 28 patients. There were also 28 healthy controls. Uterine artery blood velocity ...
Olusanya Bolajoko O BO Maternal and Child Health Unit, Department of Community Health and Primary Care, College of Medicine, University of Lagos, Surulere, Lagos, Nigeria. - - 2012
To determine adverse perinatal outcomes that portend neuro-developmental problems in the offspring of mothers with hypertensive disorders of pregnancy (HDP) in a low-income country. A cross-sectional study of surviving mother-infant pairs in southwest Nigeria. Of 3491 mothers enrolled, 216 (6.2%) were diagnosed with HDP comprising chronic hypertension (4.6%), pregnancy-induced hypertension ...
Gérardin Marie - - 2011
PURPOSE: Because of the increase of cannabis use, healthcare professionals are more and more confronted with pregnancies which have been exposed to this drug. There may be health consequences during the course of pregnancy and also for the babies throughout their development. We have made a study in order to ...
Lawlor Debbie A - - 2011
Background- Maternal diabetes mellitus in pregnancy results in greater offspring adiposity at birth. It is unclear whether it is associated with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or shared familial characteristics. Methods and Results- A record-linkage prospective cohort study of 280 866 singleton-born ...
Mendelson Tamar T Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. - - 2011
Alteration to blood flow in the maternal-foetal compartment has been proposed as a mechanism underlying maternal psychological effects on pregnancy outcomes. This study characterised the progression of umbilical and uterine blood flow resistance in healthy pregnancies and evaluated concurrent and longitudinal associations with maternal anxiety and other psychological factors. The ...
Gérardin Marie - - 2011
Because of the increase of cannabis use, healthcare professionals are more and more confronted with pregnancies which have been exposed to this drug. There may be health consequences during the course of pregnancy and also for the babies throughout their development. We have made a study in order to evaluate ...
Brown Mark A MA Department of Renal Medicine, St. George Hospital and University of NSW, Sydney, NSW, Australia. - - 2012
Mercury sphygmomanometry is being replaced with automated blood pressure (BP) recording. We tested the potential impact of this change on the outcomes of pregnant women with hypertension. Following routine detection of hypertension by mercury sphygmomanometry, 220 pregnant women with hypertension were randomized to have all subsequent BPs recorded with either ...
Cruz-Martinez Rogelio - - 2011
OBJECTIVE: To evaluate the incidence and clinical outcome of inadvertent septostomy after fetoscopic laser therapy for twin-twin transfusion syndrome (TTTS). METHODS: In a cohort of 414 consecutive monochorionic twin pregnancies treated with laser, the incidence of post-operative septostomy within one week of the procedure was prospectively recorded, and the rate ...
Lee J - - 2011
Fetal lung maturation and respiratory outcomes are influenced by the exposure to intrauterine inflammation. Funisitis is considered as the histologic hallmark of fetal inflammatory response. This study was performed to determine if there is a difference in the rate of neonatal respiratory distress syndrome (RDS) according to the presence or ...
Oddsdóttir Charlotta - - 2011
During late gestation in the mare, rapid fetal growth is accompanied by considerable placental growth and further invasion of the endometrium by microvilli. This growth requires extensive remodeling of the extracellular matrix (ECM). In early pregnancy, we know that matrix metalloproteinase (MMP)-9 and -2 are involved in the endometrial invasion ...
Courbiere Blandine - - 2011
To evaluate the obstetric outcome of women with IVF pregnancies hospitalized for ovarian hyperstimulation syndrome (OHSS). A case-control study. Department of Obstetrics-Gynecology and Reproductive Medicine. All IVF patients hospitalized for OHSS with a positive pregnancy test matched to an IVF pregnancy control group who did not develop OHSS. Retrospective study ...
Akolekar Ranjit - - 2011
Objective: To examine the feasibility of fetal RHD genotyping at 11-13 weeks' gestation from analysis of circulating cell-free fetal DNA (ccffDNA) in the plasma of RhD negative pregnant women using a high-throughput robotic technique. Methods: Stored plasma (0.5 ml) from 591 RhD negative women was used for extraction of ccffDNA ...
Triche Elizabeth W - - 2011
Increasing interest has focused on maternal nutrition and micronutrient status during pregnancy and respiratory disease development in the offspring. To examine the relationship between maternal anemia in pregnancy with wheeze and asthma in early childhood. The cohort included children of women followed through pregnancy and recontacted when the child was ...
Al Qahtani Nourah H - - 2011
OBJECTIVE: To review the pregnancy outcome in women with previous complete uterine rupture. METHODS: Hospital records of uterine rupture were reviewed from January 1981 to June 2010. All files of these patients were reviewed and patients were contacted by telephone calls to inquire about any further pregnancies after the uterine ...
Tuuli M G - - 2011
Oxygen is necessary for life yet too much or too little oxygen is toxic to cells. The oxygen tension in the maternal plasma bathing placental villi is <20 mm Hg until 10-12 weeks' gestation, rising to 40-80 mm Hg and remaining in this range throughout the second and third trimesters. ...
Umbers Alexandra J - - 2011
The pathogenetic mechanisms of fetal growth restriction associated with placental malaria are largely unknown. We sought to determine whether placental malaria and related inflammation were associated with disturbances in the insulin-like growth factor (IGF) axis, a major regulator of fetal growth. We measured IGF-1 and IGF-2 concentrations in plasma from ...
Hou Y-P - - 2011
The dynamics of nickel (Ni) uptake, transfer, retention and clearance in fetuses and late gestational rats were investigated by assessing its distributions in placenta, maternal and fetal organs and tissues during the 24 h period after a single dose of (63)Ni intraperitoneal injection on gestational day 20. Peak (63)Ni radioactivity was ...
Brunton Paula J - - 2011
The major changes in highly dynamic neuroendocrine systems that are essential for establishing and maintaining pregnancy are outlined from studies on rodents. These changes optimise the internal environment to provide the life support system for the placenta, embryo and fetus. These include automatic prevention of further pregnancy, blood volume expansion, ...
Bianchi Vincenza - - 2011
AIMS: Contrasting data are available on the diagnostic accuracy of carbohydrate-deficient transferrin (CDT) during pregnancy. These differences may depend in part on how CDT was evaluated and expressed. Here, we report on variations of CDT levels in pregnant women using the high performance liquid chromatography (HPLC) candidate reference method. METHODS: ...
Cabrera Yasmina - - 2011
Background:  The development of safe and effective techniques for second-trimester abortion (associated or not with fetal death) has become a major clinical challenge. Aims:  To compare the efficacy and safety of sublingual versus vaginal misoprostol for mid-trimester pregnancy termination. Methods:  We conducted a meta-analysis of published randomised controlled trials that ...
Figueras Francesc - - 2011
Intrauterine growth restriction (IUGR) remains one of the main challenges in maternity care. Improvements have to start from a better definition of IUGR, applying the concept of the fetal growth potential. Customized standards for fetal growth and birthweight improve the detection of IUGR by better distinction between physiological and pathological ...
Petroff M G MG Department of Anatomy & Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA. - - 2011
Pregnancy induces priming of the maternal cellular and humoral immune systems. The paternally-inherited fetal antigens that influence maternal T and B cells include both major and minor histocompatibility antigens - the same antigens that are problematic in allotransplantation. Animal models have facilitated our understanding of the lymphocyte responses to fetal ...
Fujita Yasuyuki - - 2011
The isovolumetric contraction time (ICT) is known to be an index of cardiac contractility. In this study, we examined the relationship between the fetal ICT and fetal heart rate (FHR) and evaluated the usefulness of ICT in the assessment of fetal cardiac contractility in cases with fetal tachyarrhythmia. Seven cases ...
Yazawa Hiroyuki - - 2011
Although a uterine leiomyomectomy or adenomyomectomy is an accepted procedure to treat symptoms such as dysmenorrhea or hypermenorrhea to enhance fertility, the risk of future uterine rupture is a major concern for patients who become pregnant following these surgery. Although uterine rupture very rarely occurs, this is the most feared ...
Thomas Jan E - - 2011
Scand J Caring Sci; 2011 Fathering in the first few months Becoming a parent is a major event in life. Pregnancy is a time when both physical and emotional changes affect the lives of expectant parents as they prepare for parenthood. The aim of this study was to focus on ...
Zhang Lin - - 2011
OBJECTIVE: We estimated the success rates of cytogenetic analyses in different tissue samples after intrauterine fetal deaths and analyzed the value of cytogenetic testing for determining the causes. METHODS: Women with intrauterine fetal deaths (occurring at > 10 weeks of gestation) were offered either invasive testing before medical induction of ...
Santo Susana - - 2011
OBJECTIVE: The aim of this study is to outline the aetiology and outcome of a series of fetuses with non-immune hydrops (NIH), detected prenatally. The findings are compared with a comprehensive review of recent reports. METHODS: This is a retrospective study reviewing all pregnancies complicated by NIH in the fetus ...
Kirkegaard Ida - - 2011
To evaluate whether measuring pregnancy-associated plasma protein A (PAPP-A) and free β-human chorionic gonadotrophin (β-hCG) before 10 weeks of gestation affect the association between these biomarkers and adverse pregnancy outcomes. Singleton pregnant women (9450) who attended the prenatal screening program, Aarhus University Hospital, Denmark, were included. Maternal serum levels of ...
Maloney Elizabeth - - 2011
Background:  Previous research suggests that alcohol use during pregnancy and breastfeeding has a negative impact on birth and neonatal outcomes. No threshold for this effect has been determined. The aim of this study is to determine the prevalence and correlates of alcohol use in pregnancy and lactation in a large ...
Hill Melissa M Fetal Medicine Unit, University College London Hospitals NHS Foundation Trust, London, - - 2011
Fetal sex determination is performed for women who carry X-linked conditions, for example Duchenne muscular dystrophy (DMD), or those associated with ambiguous genitalia, for example congenital adrenal hyperplasia (CAH). Non-invasive prenatal diagnosis (NIPD) using cell-free fetal DNA (cffDNA) in maternal plasma is an alternative to invasive prenatal diagnosis (IPD), which ...
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