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Murphy Michelle M - - 2007
Compromised cobalamin status during pregnancy may put both mother and child at risk of deficiency during lactation and subsequent development. We investigated whether changes in cobalamin status during pregnancy are associated with impaired status in the mother and the cord. Plasma cobalamin, methylmalonic acid (MMA), and holotranscobalamin (holoTC) concentrations were ...
Farina Mariana Gabriela - - 2007
The release of arachidonic acid from membrane glycerophospholipids through the action of phospholipases (PLs) is the first step in the biosynthesis of prostaglandins (PGs). In reproductive tissues, the most important PLs are cytosolic PLA(2) (cPLA(2)) and types IIA and V of the secretory isoform (sPLA(2)). The aim of this work ...
Joesch Jutta M JM Battelle Centers for Public Health Research and Evaluation, 1100 Dexter Avenue N, Suite 400, Seattle, WA 98109-3598, USA. - - 2008
To provide for the United States yearly estimates of first-time (primary) cesareans prior to labor and to examine factors associated with 1979-2004 trends. We estimated the annual percent of total, primary, and repeat cesareans with and without labor for 15- to 44-year-old women with live births in the 1979-2004 National ...
Carbillon Lionel - - 2007
Tyzio et al. (Reports, 15 December 2006, p. 1788) reported that maternal oxytocin triggers a transient excitatory-to-inhibitory switch of gamma-aminobutyric acid (GABA) signaling during labor, thus protecting the fetal rat brain from anoxic injury. However, a body of evidence supports the possibility that oxytocin is released from the fetal pituitary ...
Thirumagal Bavananthan - - 2007
BACKGROUND: A rectal tear with an intact anal sphincter is an unusual presentation. Failure to recognize or repair perineal and rectal lesions increases the chance of fistulas and incontinence. CASE: A 37-year-old woman, para 1, was admitted with spontaneous onset of labor at 36 weeks following an uncomplicated pregnancy. During ...
Brown Donald Corey - - 2007
This paper reviews the benefits and effectiveness of hypnosis in obstetrics and labor and delivery, demonstrating significant reductions in the use of analgesics and anesthesia and in shorter Stages 1 and 2 labors. It presents empirical and theoretical rationales for use of hypnosis in preterm labor (PTL) and labor and ...
Schifrin Barry S - - 2007
Despite almost universal fetal monitoring during labor, debates over its role and benefits persist in the medical community and in obstetric negligence lawsuits. Irrespective, there is widespread agreement that improvement in perinatal outcome is possible and that the events of labor contribute significantly to perinatal hazards. Timely application and proper ...
Korell Allison N - - 2007
BACKGROUND: Severe obstructed labor with a pelvic fistula is associated with significant fetal and maternal morbidity and mortality. It is rare in the developed world due to access to health care and availability of cesarean section for labor dystocia. CASE: A 25-year-old primigravida in denial of her pregnancy due to ...
Norwitz Errol R - - 2007
The timely onset of labor and birth is an important determinant of perinatal outcome. Prolonged (postterm) pregnancy--defined as delivery at or beyond 42 weeks' gestation--complicates 10% of all gestations and is associated with increased risks to both fetus (stillbirth, macrosomia, birth injury, meconium aspiration syndrome) and mother (cesarean delivery, severe ...
Evron Shmuel - - 2007
PURPOSE OF REVIEW: This article reviews the challenging practice of systemic analgesia as an alternative to epidural analgesia for labor pain, and places remifentanil within the context of opioid analgesics suitable for managing for labor pain. RECENT FINDINGS: Although systemic opioids have long been used for labor analgesia, they have ...
Garfield Robert E RE University of Texas Medical Branch, Department of Obstetrics and Gynecology, Division of Reproductive Sciences, 301 University, Route 1062, Galveston, TX 77555, United States. - - 2007
Presently, there is no effective treatment for preterm labor. The most obvious reason for this anomaly is that there is no objective manner to evaluate the progression of pregnancy through steps leading to labor, either at term or preterm. Several techniques have been adopted to monitor labor, and/or to diagnose ...
Srinivas Sindhu K - - 2007
OBJECTIVE: To identify a group of clinical factors that could be used to accurately predict failure in women attempting vaginal birth after cesarean (VBAC). METHODS: We conducted a planned secondary analysis of a retrospective cohort study of women who were offered VBAC from 1996 to 2000 in 17 community and ...
Vayssiere C - - 2007
OBJECTIVE: To determine the diagnostic value of fetal ST-segment analysis (STAN) in predicting neonatal acidosis. METHODS: The STAN S21 was used to monitor singleton fetuses in labor with abnormal FHR. Physicians later reviewed tracings to identify any ST events dictating intervention. Outcome measures were umbilical artery pH< or =7.15 and ...
Reichman Orna O Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel. - - 2008
Our purpose was to study prospectively the efficacy of digital rotation in reducing the prevalence of persistent occipito-posterior position (POP) and its consequences. Sixty-one women with a singleton pregnancy were enrolled prospectively between July 2003 and July 2004. They were in the second stage of labor with the fetal head ...
Manzanares S - - 2007
OBJECTIVE: To evaluate the outcome of active induction of labor for isolated oligohydramnios in low-risk term gestation. METHODS: This retrospective study analyzed the obstetric and perinatal outcome of 412 singleton term pregnancies with cephalic presentation and no maternal risk factors or fetal abnormalities. Two groups were compared: 206 deliveries after ...
Heimstad Runa - - 2007
OBJECTIVE: To compare induction of labor at gestational age 41 weeks with expectant management in regard to neonatal morbidity. Secondary aims were to assess the effect of these managements on mode of delivery and maternal complications. METHODS: Between September 2002 and July 2004, postterm women with singleton cephalic presentation and ...
Peregrine Elisabeth - - 2007
OBJECTIVE: To assess clinical and sonographic fetal head position before induction of labor, position at delivery, and whether occiput posterior (OP) position is associated with adverse delivery outcome. METHODS: Abdominal palpation and ultrasonographic fetal head and spine position were determined at 36 weeks or more of gestation in 289 women ...
Grobman William A - - 2007
OBJECTIVE: To compare pregnancy outcomes in women with one prior low-transverse cesarean delivery after induction of labor with pregnancy outcomes after spontaneous labor. METHODS: This study is an analysis of women with one prior low-transverse cesarean and a singleton gestation who underwent a trial of labor and who were enrolled ...
Breuiller-Fouche Michèle - - 2007
BACKGROUND: Studies on the human myometrium have reported on different microarrays containing different sets of genes or ESTs. However each study profiled only a small number of patients due to various constraints. More profiling information would be an addition to our knowledge base of parturition. METHODS: We compiled from five ...
Bueno B - - 2007
OBJECTIVE: To analyze the clinical and sonographic variables that predicts the success of labor induction. STUDY DESIGN: We studied the Bishop score, cervical length and parity in 196 pregnant women in the prediction of successful vaginal delivery within 24 h of induction. Logistic regression and segmentation analysis were performed. RESULTS: ...
Grammatopoulos Dimitris K - - 2007
The mechanism of human labor remains a scientific enigma. Corticotropin-releasing hormone (CRH), a hypothalamic peptide that controls the response of the body to stress and which is also produced by the placenta and intrauterine tissues during pregnancy is potentially involved in the onset of labor. CRH is part of a ...
Tanase Yasuhito - - 2007
Spontaneous pneumothorax is rare during pregnancy. A case of spontaneous pneumothorax occurring at 34 weeks' gestation in a healthy 25-year-old primigravida is described. Its occurrence was accompanied by sudden onset of dyspnea and pleuritic chest pain while the patient was walking. Diagnosis was made by chest radiograph and treatment was ...
Weiss Amir - - 2007
The role of the matrix metalloproteinases (MMPs) in the decidua, fetal membranes and amniotic fluid (AF) has been receiving more and more attention. The MMPs are not only important intermediaries in pathological processes leading to preterm labor but it seems that they also play a crucial role in the activation ...
Szunyogh Norbert - - 2007
OBJECTIVES: To assess ductus venosus (DV) indices during the first stage of labor and the effect of ruptured membranes, meconium stained liquor and epidural analgesia (EDA). METHODS: Prospective cross-sectional study. Eighty-one women with low-risk singleton term pregnancies participated, 51 had normal labor (Group 1), and 30 experienced ruptured membranes and/or ...
Mota-Rojas Daniel - - 2007
Oxytocin is extensively used to induce or augment uterine contractions, especially to facilitate the third stage of labor in humans. Administration of oxytocin to parturient sows reduces duration of labor whereas mortality of the offspring may remain unchanged. This study aimed to evaluate whether time of administration of oxytocin during ...
Sadan Oscar - - 2007
Umbilical cords often become encircled around portions of the fetus, usually the neck. The incidence ranges from 21% in one loop to 0.2% in three loops. In the present study, we assessed the practice of severing the cord, which was encircled once around the neck of the fetus, after delivery ...
Pomini Francesco - - 2007
Preterm labor is one of the most important factors limiting the advancement of fetal surgery programs. While prostaglandins (PGs) have long been indicated as the key factor in the initiation of labor in humans, there is significant evidence showing that the chorionic membrane acts as a powerful barrier between the ...
Vasconcelos Marcos Salem - - 2007
BACKGROUND: The etiology of obsessive-compulsive disorder (OCD) remains unknown, although it is thought to involve an interaction of genetic and environmental factors. This study aimed to identify prenatal, perinatal, and postnatal risk factors in OCD. METHODS: We compared retrospectively 68 OCD patients to 70 control subjects based on responses given ...
Chen Sheng-Huan - - 2006
A 32-year-old parturient requested epidural analgesia for labor. A lumbar epidural block was performed at the L1-2 interspace. Thirty minutes after the loading dose of the local anesthetic mixture, she suffered numbness in both arms and high sensory block up to the C6 dermatome without significant motor blockade. The retained ...
Peaceman Alan M - - 2006
OBJECTIVE: The purpose of this study was to determine the influence of change in infant birth weight between pregnancies on the outcome of a trial of labor for women whose first cesarean delivery was performed for dystocia. STUDY DESIGN: Secondary analysis of 7081 patients with 1 previous cesarean delivery and ...
Danon D - - 2007
OBJECTIVE: To evaluate the maternal and neonatal outcomes of pregnancies complicated with isolated oligohydramnios at term, managed by induction of labor. METHODS: We conducted a retrospective case-control study. 138 women with uncomplicated oligohydramnios at term [amniotic fluid index (AFI) < or =5 cm] and a low Bishop score (< or ...
Lamvu Georgine M - - 2006
OBJECTIVE: To conduct a retrospective, cohort study to determine the impact of abnormal outpatient fetal heart rate (FHR) testing on maternal interventions in labor, including labor induction, operative vaginal delivery and unplanned cesarean section. STUDY DESIGN: Our cohort consisted of 1,386 women with singleton gestations who had outpatient fetal nonstress ...
Lin Monique G - - 2006
Criteria for failed labor induction have not been standardized. The increasing prevalence of labor induction and the lack of a definition for failed induction contribute to unnecessary abdominal deliveries. Labor duration, cervical dilation, and uterine activity necessary to attain the active phase are reviewed. A practical definition of failed induction ...
Althaus Janyne E - - 2006
OBJECTIVE: The purpose of this study was to determine if intrapartum contractions of a particular shape (rapid rise with slower return to baseline) are predictive of cephalopelvic disproportion (CPD). STUDY DESIGN: In an institutional review board (IRB)-approved study, cohorts of 100 women who underwent spontaneous vaginal delivery (SVD) and 100 ...
Caughey Aaron B - - 2006
OBJECTIVE: Studies of cesarean delivery (CD) rates among women undergoing induction of labor (IOL) often compare such women to women experiencing spontaneous labor at similar gestational ages. We sought to examine the association between IOL at various gestational ages and CD, accounting for the effect of increased gestational age among ...
Allen Victoria M - - 2006
OBJECTIVE: To examine the cumulative costs of hospital care in the first and subsequent pregnancies associated with different methods in the initial delivery of nulliparous women. METHODS: An 18-year population-based cohort study (1985-2002) using the Nova Scotia Atlee Perinatal Database compared cumulative delivery costs in the first and subsequent pregnancies. ...
Strobel E - - 2006
OBJECTIVES: To determine the ability of Bishop score and sonographic cervical length to predict time to spontaneous onset of labor and time to delivery in prolonged pregnancy. METHODS: Ninety-seven women underwent transvaginal ultrasound examination and palpation of the cervix at 291-296 days' gestation according to ultrasound fetometry at 12-20 weeks' ...
Heimstad Runa - - 2006
OBJECTIVE: The aim of the study was to evaluate pregnancy outcomes by weeks of gestation. A second aim was to assess the outcomes in groups with spontaneous or induced labor. METHODS: This was a prospective cohort study of singleton pregnancies delivered after 37 weeks of pregnancy covering a well defined ...
Hwa Hsiao-Lin - - 2006
BACKGROUND/PURPOSE: Regional analgesia for labor pain relief is effective and widely used. This study evaluated the controversial association between mode of operative delivery and patient-elective labor regional analgesia. METHODS: We retrospectively compared the rates of instrumental vaginal and cesarean deliveries in parturients before the introduction, in the first 15 months ...
Reinheimer Torsten M - - 2006
Preterm labor (PTL) affects up to 25% of human pregnancies in developing countries, but there are few therapeutic options. Based on the key role of oxytocin (OXT) in labor and parturition, OXT antagonists are a potentially useful class of drugs for PTL. Barusiban is a new selective, potent, and long-acting ...
Jao Mei-Shan - - 2006
BACKGROUND: Anaphylaxis is an uncommon event during pregnancy, but if it does arise, it can lead to serious fetal consequences even if there are no serious long-term maternal complications. CASE: A parturient developed anaphylaxis in the labor unit shortly after intravenous cefazolin chemoprophylaxis had begun for perinatal group B streptococcal ...
Orbach-Zinger S - - 2006
AIM: To identify parturients at risk of inability to extend labor epidural analgesia in whom alternative methods of anesthesia should be considered for Cesarean section (CS). METHODS: For 6 months, we prospectively studied women undergoing CS with a functioning epidural catheter in place from the delivery ward. All parturients received ...
Allen Victoria M - - 2006
OBJECTIVE: To estimate the maternal morbidity associated with cesarean deliveries performed at term without labor compared with morbidity associated with induction of labor at term. METHODS: A 15-year population-based cohort study (1988-2002) using the Nova Scotia Atlee Perinatal Database compared maternal outcomes in nulliparous women delivering by cesarean delivery without ...
Pacheco Luis D - - 2006
The purpose of this study was to evaluate the efficacy of the concomitant use of subcutaneous terbutaline and oxytocin for the management of uterine hyperstimulation. Patients in active labor receiving intravenous oxytocin who developed uterine hyperstimulation were randomly assigned to receive either oxytocin discontinuation or administration of subcutaneous terbutaline while ...
Hong J Y - - 2006
BACKGROUND: Many studies have addressed the specific perinatal risks of surgery and anesthesia during pregnancy, but there is still much undetermined. The objective of this retrospective review was to compare the adverse pregnancy outcome in patients undergoing laparoscopy and laparotomy with inhalational or regional anesthesia for adnexal mass in pregnancy. ...
Goto Kenji - - 2006
BACKGROUND: A microperforate hymen is a rare congenital hymenal anomaly frequently mistaken for an imperforate hymen. While an imperforate hymen is suggested when hematocolpos is present and the hymen bulges and is discolored by retained menstrual blood, a microperforate hymen is an incomplete obstructive anomaly usually permitting normal menstrual flow. ...
Tan Peng Chiong - - 2006
OBJECTIVE: To determine coital incidence at term and to estimate its effect on labor onset and mode of delivery. METHODS: Healthy women with uncomplicated pregnancies and established gestational age were recruited to keep a diary of coital activity from 36 weeks of gestation until birth and to answer a short ...
Briggs Gerald G - - 2006
PURPOSE: The drug therapy of common conditions and complications during labor and delivery and the fetal and neonatal effects of this therapy are examined. SUMMARY: The pharmacologic therapy of common conditions that occur in labor and delivery primarily involves oxytocin and prostaglandins for cervical ripening and labor induction and systemic ...
Le Ray C - - 2006
OBJECTIVE: To analyze the influence of level of perinatal care of the maternity unit on the rate of cesarean delivery during labor among women with low-risk pregnancies. METHODS: Using data from the PREMODA (PREsentation et MODe d'Accouchement: presentation and mode of delivery) study of 138 French maternity units, the delivery ...
Wölfler Monika M - - 2006
OBJECTIVE: We aimed to determine whether isosorbide mononitrate (IMN) given simultaneously with dinoprostone in term pregnancies is superior to dinoprostone alone to promote delivery. STUDY DESIGN: One hundred and twenty nulliparous women at term were randomly assigned to receive per vaginam IMN 40 mg or placebo in addition to 3 ...
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