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Results 101 - 150 of 1076
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Rattasumpun Prapa - - 2008
PURPOSE: To gain an understanding of the lived experience of pregnant women in Thailand who have preterm labor. STUDY DESIGN AND METHODS: Phenomenology using purposeful sampling with pregnant Thai women diagnosed with preterm labor and admitted to two government hospitals in Bangkok, Thailand. A semi-structured interview was conducted in the ...
Fonseca Linda - - 2008
OBJECTIVE: The purpose of this study was to compare the vaginal delivery rate in women who undergo labor induction with preinduction misoprostol or oxytocin alone. STUDY DESIGN: Women with singleton pregnancies and Bishop scores <5 with labor induction at > or = 24 weeks of gestation were eligible; they were ...
Field Tiffany - - 2008
This review covers research from the last 5 years on the most popular complementary and alternative therapies used during pregnancy and labor and potential underlying biological bases for their effects. MEDLINE was searched and papers were reviewed for the most popular complementary and alternative therapies used during pregnancy and labor, ...
Chaiworapongsa Tinnakorn - - 2008
The fetus is thought to play a central role in the onset of labor. Pulmonary surfactant protein (SP)-A, secreted by the maturing fetal lung, has been implicated in the mechanisms initiating parturition in mice. The present study was conducted to determine whether amniotic fluid concentrations of SP-A and SP-B change ...
Mancuso Melissa S - - 2008
Cesarean delivery is indicated at any stage in the labor process in the presence of nonreassuring fetal status or when conservative measures fail in the setting of abnormal labor. In the absence of maternal or fetal indications for expedited delivery, cesarean delivery is not indicated for latent phase disorders. When ...
Gotsch Francesca - - 2008
Caspase-1 is a component of the NALP3 inflammasome, a cytosolic multiprotein complex that mediates the processing of pro-inflammatory caspases and cytokines. The inflammasome represents the first line of defense against cellular stress and is a crucial component of innate immunity. Caspase-1 is the enzyme responsible for the cleavage and activation ...
Mittal Pooja - - 2008
CXCL6 is a potent pro-inflammatory neutrophil chemoattractant and activator whose activity during pregnancy is not well-established. The purpose of this study was to determine if CXCL6 is present in amniotic fluid (AF) and if CXCL6 concentrations in AF change with labor (pre-term and term) or intra-amniotic infection/inflammation (IAI). A cross-sectional ...
Divon Michael Y - - 2008
The standard definition of a prolonged pregnancy is 42 completed weeks of gestation. The incidence of prolonged pregnancy varies depending on the criteria used to define gestational age at birth. It is estimated that 4 to 19% of pregnancies reach or exceed 42 weeks gestation. Several studies that have used ...
Heng Yujing J - - 2008
OBJECTIVE: The objective of the study was to investigate temporal changes in interleukin-1 receptor antagonist (IL-1ra) in human cervicovaginal fluid (CVF) in term pregnancy and labor. STUDY DESIGN: CVF was collected weekly from 155 multiparous women from 36 weeks' gestation until labor. High vaginal swabs were collected for microbiology assessment. ...
Orji Ernest - - 2008
OBJECTIVE: To evaluate the progress of labor in nulliparas and multiparas using the modified World Health Organization (WHO) partograph. METHOD: In a prospective study 259 nulliparas and 204 multiparas were compared for rates of normal labor progression in the active phase; of cervical dilatation plots crossing the alert line of ...
Kashanian Maryam - - 2008
OBJECTIVE: To evaluate the effect of dexamethasone administration on labor duration. METHOD: In this controlled trial 122 nulliparous women with a full-term pregnancy and a Bishop score of 7 or greater were randomly assigned to receive a single 8-mg dose of dexamethasone or placebo 6 hours before initiation of labor ...
Liu Baogang B Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1009, - - 2008
Labor pain derives primarily from stimulation of afferents innervating the uterine cervix and lower uterine segment. The authors have previously shown that the excitability of these afferents is regulated by sex hormones and test in this study whether pregnancy also alters their excitability. After animal care committee approval, Sprague-Dawley rats ...
Velez Digna R - - 2008
BACKGROUND: Preterm birth (PTB) is hypothesized to be an inflammatory response disease. However, no single factor alone is likely to explain PTB risk. It is more probable that coordinated networks of cytokines affect risk. METHODS: Therefore, we examined the relationships between amniotic fluid (AF) cytokines/chemokines and related biomarkers in PTB ...
Barrows Jeffrey - - 2008
Despite the legislation passed in the 19th century outlawing human slavery, it is more widespread today than at the conclusion of the civil war. Modern human slavery, termed human trafficking, comes in several forms. The most common type of human trafficking is sex trafficking, the sale of women and children ...
Nicholson James M - - 2008
The purpose of this study was to compare birth outcomes that result from the active management of risk in pregnancy at term (AMOR-IPAT) to those outcomes that result from standard management. This was a randomized clinical trial with 270 women of mixed parity. AMOR-IPAT used preventive labor induction to ensure ...
Mo A - - 2008
OBJECTIVES: To characterize patterns of uteroplacental separation during the third stage of labor, and to investigate their association with previous history of Cesarean section (CS), delays in placental separation and blood loss. METHODS: In this cohort observational study, continuous ultrasound imaging of uteroplacental separation was performed during the third stage ...
Kim Hyun Hee - - 2008
Sophrology, based on a combination of Western relaxation therapy and Eastern yoga and meditation might decrease maternal stress during labor. This study aimed to evaluate whether prenatal sophrologic childbirth preparation may decrease maternal and neonatal adverse response associated with delivery. In a nested case-control study, 69 nulliparous, singleton pregnant women ...
Hill Christina C - - 2008
Pregnancy is associated with physiologic changes that affect virtually every organ system in the mother. These physiologic changes allow the parturient to support the growing uterus and fetus and to withstand labor and the postpartum course. Because the gravida may require surgery while pregnant, it is important to have an ...
Mantha V R R - - 2008
BACKGROUND: This prospective, randomized study was performed to see if intermittent labor epidural analgesia was protective against maternal intrapartum fever, compared to continuous epidural infusion. METHODS: Ninety-two healthy, term, nulliparous women in spontaneous labor were assigned to either intermittent (ILEA) or continuous labor epidural analgesia (CLEA), 46 in each group. ...
Vankayalapati P - - 2008
OBJECTIVES: To evaluate the usefulness of sonographic assessment of cervical length in the prediction of spontaneous onset of labor and of vaginal delivery. METHODS: Two hundred and six women who attended a dedicated postdates clinic at 41 + 3 weeks of pregnancy and agreed to the assessment of cervical length ...
Jakovljevic Mihajlo - - 2008
OBJECTIVES: In countries with high income, tocolytic therapy with beta-mimetic agents is a cost-effective strategy compared to placebo. In our study, the cost-effectiveness of two beta-mimetic agents, ritodrine and fenoterol, used in the management of preterm labor was compared in the setting of a low-middle-income transitional country, Serbia & Montenegro. ...
Lee Si Eun - - 2008
OBJECTIVES: The role of prostaglandins (PGs) in the onset of human parturition has been controversial. Specifically, some investigators have proposed that PGs are the consequence rather than the cause of labor. An important question is whether or not amniotic fluid (AF) PG concentrations increase before the onset of labor in ...
Shi Shao-Qing SQ Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, - - 2008
This study was undertaken to use artificial neural networks on uterine electromyography data to identify term and preterm labor in rats. Controls (group 1: n = 4) and preterm labor models (group 2: n = 4, treated with onapristone) were used. Uterine electromyography and intrauterine pressure (IUP) variables were measured ...
Fox Nathan S - - 2008
OBJECTIVE: To compare the accuracy of clinically estimated fetal weight (EFW) obtained at the beginning and end of labor. METHODS: The clinical EFWs obtained by obstetricians at the beginning (initial EFW) and end (repeat EFW) of labor were compared to determine the accuracy of the estimates in 138 women with ...
Ojala Kati - - 2008
OBJECTIVE: To study interobserver agreement in the assessment of intrapartum automated fetal electrocardiogram ST interval analysis (STAN). DESIGN: Observational study. SETTING: Labor ward in tertiary level university hospital. Sample. Two hundred (140 reassuring and 60 non-reassuring) STAN recordings on non-selected women with singleton, vertex, term pregnancies were selected from our ...
Tanir H M - - 2008
OBJECTIVE: This study was designed in an aim to compare the efficacies of three labor induction methods, dinoprostone (PGE2) vaginal insert with or without concomittant oxytocin and misoprostol (PGE1) combined with oxytocin infusion. METHODS: This was a prospective observational trial of nulliparous women undergoing labor induction from December 2006 to ...
Wiberg-Itzel Eva - - 2008
OBJECTIVES: To assess whether there is an association between high lactate concentration in amniotic fluid (AF) and labor dystocia. DESIGN: Prospective observational study. SETTING: Labor ward at General South Hospital, Stockholm, Sweden. POPULATION AND METHODS: Women in active labor attending labor ward, having at least two consecutive measurements of lactate ...
Baciuk Erica P - - 2008
ABSTRACT: BACKGROUND: To evaluate the association between water aerobics, maternal cardiovascular capacity during pregnancy, labor and neonatal outcomes. METHODS: A randomized, controlled clinical trial was carried out in which 34 pregnant women were allocated to a water aerobics group and 37 to a control group. All women were submitted to ...
Vidaeff A C - - 2008
Much of our understanding and knowledge of human parturition has been blurred by conjecture and extrapolation. The limited available data on human parturition reflect the inability to directly experiment with pregnant human subjects. In spite of this obvious impediment and the scarcity of longitudinal data on fundamental physiological changes in ...
Wiser Amir - - 2008
OBJECTIVE: To evaluate whether C-reactive protein (CRP) levels in maternal serum at post-date follow-up can predict the mode of onset of spontaneous delivery in term pregnancies and the interval to delivery. STUDY DESIGN: Women at 40 completed weeks of gestation were recruited. The interval from CRP sampling to delivery and ...
Schaub Andreas F - - 2008
OBJECTIVE: To determine whether the obstetric gel shortens the second stage of labor and exerts a protective effect on the perineum. METHOD: A total of 251 nulliparous women with singleton low-risk pregnancies in vertex position at term were recruited. A total of 228 eligible women were randomly assigned to Group ...
Hasegawa Junichi - - 2008
OBJECTIVES: It was the aim of this study to examine intrapartum fetal heart rate (FHR) patterns in oligohydramnios. METHODS: Subjects comprised 24 singleton pregnant women diagnosed with oligohydramnios and 470 controls. FHR patterns were analyzed at the end of the first stage and throughout the whole second stage of labor. ...
Hamill Neil - - 2008
CCL20, also known as MIP-3 alpha, is a chemokine that participates in chemotaxis of immature dendritic cells, effector/memory T-cells, and B-lymphocytes. The objectives of this study were to determine whether CCL20 can be detected in amniotic fluid (AF) and if AF concentration of this chemokine changes with advancing gestational age, ...
Habek Dubravko - - 2008
AIM: We present and discuss delivery (maternal and fetal) outcome of macerated stillbirths in the third trimester. MATERIAL AND METHODS: In this retrospective observational study, the course of labor was analyzed in 10 stillborn fetuses with a varying grade of maceration during the third trimester. Medical documentation on the course ...
Tingåker Berith K - - 2008
Cervical ripening is a prerequisite for a normal obstetrical outcome. This process, including labor, is a painful event that shares features with inflammatory reactions where peripheral nociceptive pathways are involved. The capsaicin and heat receptor TRPV1 is a key molecule in sensory nerves involved in peripheral nociception, but little is ...
Romero Roberto - - 2007
Fetal development and growth occur in a sterile amniotic cavity while first exposure to microorganisms happens at birth. However, at least 25% of all preterm births, the leading cause of perinatal morbidity and mortality worldwide, occur in mothers with microbial invasion of the amniotic cavity. Microbial attack of the fetus ...
Mitchell Murray D - - 2008
Endocannabinoids have been implicated in the mechanisms of implantation, maintenance of pregnancy, and parturition in women. Intrauterine prostaglandin production and actions are also critical in each of these mechanisms. Hence, we have evaluated the effects of cannabinoids on prostaglandin biosynthesis by human gestational membranes. Explants of term amnion and choriodecidua ...
Clark Steven - - 2007
OBJECTIVE: The purpose of this study was to examine the effects of a conservative and specific checklist-based protocol for oxytocin administration on maternal and newborn outcome. The protocol was based on maternal and fetal response to oxytocin rather than infusion rate. STUDY DESIGN: This was a retrospective chart review and ...
Gómez Ponce de León R - - 2007
The frequency of intrauterine fetal death (IUFD) with retained fetus varies, but is estimated to occur in 1% of all pregnancies. The vast majority of women will spontaneously labor and deliver within three weeks of the intrauterine death. The complexity in medical management increases significantly when the cervix is unripe ...
Facchinetti Fabio - - 2007
OBJECTIVE: To determine the better performer among cervical ripening agents for the elective induction of labor. STUDY DESIGN: An open-label, randomized study was done in consecutive patients undergoing elective induction of labor at the 41st week and beyond. Inclusion criteria were: singleton pregnancy, gestational age ascertained through first-trimester ultrasound, Bishop ...
Varner Michael W - - 2007
OBJECTIVE: To estimate success rates and risks with a trial of labor after one previous cesarean delivery for multifetal gestation compared with one previous cesarean delivery for a singleton pregnancy. METHODS: Patients from the National Institute of Child Health and Human Development Maternal Fetal Medicine Units Network Cesarean Registry with ...
Altay M Metin - - 2007
AIM: To investigate how the location of the placenta at term pregnancies affects the duration of the third stage of labor and to discuss the possible mechanisms affecting the duration of the third stage. We believe that this is the first prospective study comparing the duration of the third stage ...
Mawaldi L - - 2008
OBJECTIVE: To compare the effectiveness, safety, and possible adverse effects of terbutaline and nifedipine in prolonging pregnancy beyond 48 h. METHODS: A randomized controlled trial was conducted with 174 pregnant women admitted with preterm labor randomized into 2 groups, which were given terbutaline (95 patients) and nifedipine (79 patients), respectively. ...
El Kady Dina - - 2007
Traumatic injuries although uncommon (affect 6% to 7% of all pregnancies) are associated with poor maternal, fetal, neonatal, and infant outcomes. The magnitude of the problem is most likely largely underestimated secondary to lack of standardized reporting. Newer data are available that stratify maternal risk by type of injury sustained, ...
Ekele B A - - 2007
CONTEXT: Induction of labor is always a challenge to many an obstetrician more so when the cervix is unfavorable. OBJECTIVES: To determine the efficacy and safety ofmisoprostol in cervical ripening and labour induction. MATERIALS AND METHOD: Aprospective study spanning 2 years and involving 151 patients admitted for cervical ripening and ...
Beebe Kathleen R - - 2007
OBJECTIVE: To describe levels of anxiety and self-efficacy for childbirth in nulliparous women during the late third trimester and to identify relationships among those variables, prehospitalization labor pain, management strategies, and hospital admission status. DESIGN: A longitudinal, descriptive study. PARTICIPANTS: Thirty-five English-speaking nulliparous women, 18 to 40 years of age, ...
Jin Dan - - 2007
It has been suggested that corticotropin-releasing hormone (CRH) receptors CRH-R1 and CRH-R2 might be involved in the modulation of uterine activity during pregnancy. The authors determine the localization, concentrations, and variants of CRH-R1 and CRH-R2 in the human pregnant myometrium from patients undergoing labor and patients not undergoing labor. Biopsies ...
Beilin Yaakov - - 2007
BACKGROUND: The influence of the labor epidural local anesthetic (LA) on mode of delivery has not been adequately studied. In this study, we sought to determine if there is a difference in mode of delivery among parturients who receive epidural bupivacaine, ropivacaine, or levobupivacaine. METHODS: Nulliparous women at term requesting ...
Florio P - - 2007
OBJECTIVE: Placental corticotropin-releasing factor (CRF) affects myometrial contractility and the secretion of several uterotonins such as prostaglandins (PGs); however, the activity of CRF is counteracted by CRF-binding protein (CRF-BP). At term and pre-term labor, CRF levels in maternal plasma are highest whereas those of CRF-BP are falling, and the cause ...
Battista Leah - - 2007
OBJECTIVE: The purpose of this study was to examine complications of labor induction compared to spontaneous labor in multiparas. STUDY DESIGN: This was a retrospective cohort study of multiparous women with live, singleton pregnancies at term, who had no contraindications to labor or labor induction. Cesarean delivery was the primary ...
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