Search Results
Results 201 - 250 of 661
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Parveen Zahida - - 2004
Gestational trophoblastic disease consists of a broad spectrum of conditions ranging from an uncomplicated partial hydatidiform molar pregnancy to stage-IV choriocarinoma with cerebral metastases. We describe a partial molar change in the placenta that was associated with a normal female fetus that was delivered at term and is alive and ...
Ulug Ulun - - 2004
Hydatiform mole is a gestational trophoblastic disease characterized by the dominance of dispermic fertilization. Micromanipulation techniques in assisted reproduction technologies have enabled direct evaluation of the zygotes and the formation of pronuclei in the zygote. Intracytoplasmic sperm injection (ICSI) of oocytes ensures that only a single spermatozoon enters the ooplasma. ...
Corapcioglu Funda - - 2004
Wilms' tumor in adults is rare, and no treatment guidelines have been established. Spinal cord compression has also been rarely reported in all age groups. In this case report, we present a 19-year-old adolescent with recurrent Wilms' tumor, a paraspinal dumbbell mass, metastatic involvement of the vertebral bodies, lung metastasis, ...
Breslau Naomi - - 2004
BACKGROUND: Partial PTSD, employed initially in relation to Vietnam veterans, has been recently extended to civilian victims of trauma. We examined the extent to which partial PTSD is distinguishable from full DSM-PTSD with respect to level of impairment. METHOD: A representative sample of 2181 persons was interviewed by telephone to ...
Kosaki Kenjiro - - 2004
We report a family in which a healthy, unrelated couple had a male fetus with bilateral ventriculomegaly, a normal liveborn girl, a hydatidiform molar pregnancy, a female fetus with ventriculomegaly and situs abnormalities, and a male fetus with hydrocephalus, a three-lobed left lung, and defective tracheal cilia with absent inner ...
Sebire N J - - 2004
AIM: To determine whether immunohistochemical staining for p57(KIP2), the product of the maternally expressed gene CDKN1C, can be used to differentiate between gestational trophoblastic tumours arising from a complete hydatidiform mole and those originating from non-molar pregnancies. METHODS: The immunohistochemical expression of p57(KIP2) was investigated in 23 cases of choriocarcinoma ...
Fisher Rosemary A - - 2004
This article reviews published data on familial recurrent hydatidiform mole with particular reference to the genetic basis of this condition, the likely outcome of subsequent pregnancies in affected women and the risk of persistent trophoblastic disease following molar pregnancies in these families. Familial recurrent hydatidiform mole is characterized by recurrent ...
Maxwell Cynthia - - 2004
OBJECTIVE: Primary bone and soft-tissue tumors occur rarely in pregnancy. The objective of this study was to describe the outcome of a large cohort of pregnant patients with these rare tumors. METHODS: Pregnant women diagnosed with bone or soft-tissue tumors during pregnancy or within 3 months after delivery were identified ...
Matsui Hideo - - 2004
OBJECTIVE: To analyze the outcome of the first pregnancy following chemotherapy for gestational trophoblastic tumor (GTT). STUDY DESIGN: A total of 393 patients with GTT (87 with high-risk and 306 with low-risk GTT) underwent chemotherapy at Chiba University Hospital between 1974 and 2000. Of them, 137 (19 with high-risk and ...
Seckl Michael J - - 2004
OBJECTIVE: To assess whether a complete hydatidiform mole (CHM) carries an increased risk of later requiring chemotherapy in pregnancies continued to term. STUDY DESIGN: The Charing Cross gestational trophoblastic neoplasia (GTN) database was screened between 1973 and 2002 to identify registered singleton CHMs with a known gestational age at the ...
Smith Harriet O - - 2004
OBJECTIVE: To analyze gestational trophoblastic neoplasia (GTN) trends among American Indians (AI) using population-based data. STUDY DESIGN: GTN incidence, by race and age, was calculated using data collected by the New Mexico Tumor Registry over 29 years (1973-2001). Live birth, pregnancy and women at risk were tabulated using data derived ...
Ozarpaci Cemalettin - - 2005
A 28-year-old patient gravida 3, para 2 was admitted at 16 weeks' gestation with the diagnosis of complete hydatidiform mole with coexistent live fetus (CHMCF) in dichorionic twin gestation. The betaHCG level was 530,000 mIU/ml. The pregnancy was terminated by hysterotomy. Histopathologic analysis revealed a hydatidiform mole and a 17-week-old ...
Rajput Ali H - - 2004
The objective of this study was to identify dopamine (DA) metabolism pattern in Lewy body Parkinson's disease (PD) patients with dyskinesia (Dysk) only, with wearing-off (WO) only, or no motor complications (NMC) induced by levodopa (LD). DA, homovanillic acid (HVA), 3,4-dihydroxyphenylacetic acid (DOPAC), and 3-methoxytyramine (3-MT) were measured individual basal ...
Maslovitz Sharon S Department of Obstetrics and Gynecology, Lis Maternity Hospital, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel. - - 2004
Uterine re-evacuation samples taken in cases of suspected residua after curettage are occasionally negative for gestational tissue. We aimed at evaluating the occurrence of such postcurettage re-evacuation-negative samples and at exploring factors that may influence their occurrence. This was a cross-sectional comparative retrospective study of 69 consecutive women who underwent ...
Obiechina, NJA; ;
A retrospective analysis of all cases of molar pregnancies managed at St. Charles Borromeo Hospital, Onitsha, from 1991 to 2000 was done. Fifty-nine patients were treated, but fifty-three case-notes were retrieved. The ages parity, clinical presentation, pregnancy outcome and complications following treatment, extracted the age range was 17-43 years, mean ...
Bovicelli L - - 2004
A complete mole coexisting with dichorionic twins was diagnosed by the combined use of sonography and chorionic villus sampling at 10 weeks gestation. The pregnancy resulted in the death of one fetus at 31 weeks from presumed feto-maternal haemorrhage, while the other fetus survived in good condition. A summary of ...
Pongcharoen S - - 2004
To clarify the Fas and Fas-ligand status of normal and molar trophoblast, the expression of Fas and FasL by placental trophoblast populations in partial and complete hydatidiform moles was compared with that in normal first trimester and term pregnancies using an avidin-biotin peroxidase technique on frozen and formalin-fixed paraffin-embedded placental ...
Andria Louis M - - 2004
A cephalometric analysis was designed to evaluate several factors that may affect the sagittal position of the maxillary first permanent molar. A total of 184 Class II and Class I malocclusion patients were randomly selected before orthodontic treatment. The mandibular and palatal planes were related to Frankfort Horizontal and used ...
Ngan H Y S - - 2004
The FIGO 2000 gestational trophoblastic neoplasia (GTN) staging and classification has recommended three major changes in the management of GTN. The criteria for diagnosis of GTN following molar pregnancy were defined. The methods used for investigation of spread of the disease were recommended. A major change in the concept of ...
Moore-Maxwell Crystal A - - 2004
OBJECTIVE: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic disease. Little is known about its pathogenesis and natural history. METHODS: This report describes two cases that arose in patients with documented complete hydatidiform moles and summarizes the antecedent prenatal histories of PSTTs based on a detailed ...
Shaarawy Mohamed - - 2004
Seventy-two patients with gestational trophoblastic tumors (GTTs) and 20 first-trimester healthy pregnant women (controls) participated in this study. According to the WHO scoring system, GTTs were subgrouped into 24 hydatiform mole spontaneous regression (HMSR), 18 postmolar high-risk (PMHR) and 16 low- and 14 high-risk cases of choriocarcinoma. Patients with choriocarcinoma ...
Picone O - - 2003
BACKGROUND: Cerebral metastasis of choriocarcinoma during pregnancy is rare. Described is the fourth case in the literature. CASE: A pregnant women at 28 weeks' gestation sought care for headaches followed by loss of consciousness. The diagnosis of choriocarcinoma metastases was made on the basis of the combination of cerebral and ...
Sasaki Shigeru - - 2003
We can now detect molar pregnancy at a much earlier gestational age than before by using high resolution vaginal ultrasonography. As a result, the current clinical presentation of complete hydatidiform moles has clearly changed compared to that of the classic type of mole. The diagnosis of molar pregnancy is nearly ...
Kim Seung Jo - - 2003
Placental site trophoblastic tumour (PSTT) is a very rare and unique form of gestational trophoblastic disease (GTD). This tumour represents a neoplastic transformation of intermediate trophoblastic cells that normally play a critical role in implantation. PSTT can occur after a normal pregnancy, abortion, term delivery, ectopic pregnancy or molar pregnancy. ...
Khashoggi Tariq Y - - 2003
OBJECTIVE: To study the incidence and time trends of gestational trophoblastic disease in the Kingdom of Saudi Arabia (KSA). METHODS: A retrospective study of medical records of 64,762 pregnancies registered and treated at Security Forces Hospital, Riyadh, KSA, from January 1988 through to December 1998. RESULTS: Fifty-nine cases of hydatidiform ...
Garner Elizabeth - - 2003
Current therapy for molar pregnancy and gestational trophoblastic neoplasias (GTNs) has resulted in high cure rates with preservation of fertility, even in the setting of chemotherapy for widespread metastatic disease. Data from the New England Trophoblastic Disease Center on later pregnancies following complete and partial mole, as well as persistent ...
Steigrad Stephen James - - 2003
The epidemiology of gestational trophoblastic diseases is unclear. Problems with collection and interpretation of differing data abound. Hydatidiform mole (HM) is associated with abnormal gametogenesis and/or fertilization. This is further influenced by age, ethnicity and a prior history of an HM suggesting a genetic basis for its aetiology. Whilst a ...
Xue W C - - 2003
AIMS: To assess the proliferative activity of gestational trophoblastic disease (GTD) using one of the novel proliferation markers (MCM7) and to determine its prognostic value in hydatidiform mole (HM). METHODS AND RESULTS: Immunohistochemical staining for MCM7 was performed on 122 samples of paraffin-embedded trophoblastic tissues including 22 normal first-trimester placentas, ...
Namba Akira - - 2003
BACKGROUND: Recent developments in genetic analysis allow determination of the origin of choriocarcinoma (ie, gestational or nongestational), which helps determine the strategy for clinical treatment of the disease. CASE: We present a case of ovarian choriocarcinoma forming a huge ovarian mass 40 days after the patient's last menstrual period. Deoxyribonucleic ...
Al-Hussaini T K - - 2003
OBJECTIVES: To present a series of women with recurrent molar pregnancies, including rare familial cases, and discuss etiology and treatment options. METHODS: We performed a detailed clinical evaluation and pedigree analysis of five Egyptian women with recurrent pregnancy loss due to molar pregnancy. RESULTS: The women had a history of ...
Peretz Benjamin - - 2003
No standardized therapeutic interventions have been reported for patients diagnosed with breast cancer during pregnancy. A high risk for malformations in the fetus has been claimed when chemotherapy is administered during the first trimester of the pregnancy. Tooth formation of the primary teeth begins at 11 to 14 weeks of ...
Kumar Neeta - - 2003
BACKGROUND: Gestational trophoblastic disease (GTD) adversely affects pregnancy by the development of Hydatidiform mole and placental site gestational tumor. GTD is a discrete pool of epidemiological and clinicopathological entities. Therefore, every geographical region should be studied separately. The Indian subcontinent is under-reported for this disease. This paper analyses the data ...
Vardimon Alexander D - - 2003
PURPOSE: To examine contact point (CP) tightness of the mandibular dental arch in cases with a unilateral first molar (M1) missing, and also investigate the influence of time since extraction on CPs tightness. METHODS: CPs tightness was measured with a tightness of dental contact point device in 29 patients (9 ...
Fallahian M - - 2003
Familial molar pregnancies and gestational trophoblastic disease are exceedingly rare. In this case report, a family including four sisters and their cousin had molar pregnancies. Eldest sister had repeated molar pregnancies. Second sister had early abortion at her first pregnancy and partial molar pregnancy following blighted ovum by intrauterine insemination ...
Ajithkumar T V - - 2003
Placental site trophoblastic tumor (PSTT) is an uncommon form of gestational trophoblastic disease (GTD) with variable spectrum of clinical behavior. PSTT can occur after a normal pregnancy, spontaneous abortion, termination of pregnancy, ectopic pregnancy or molar pregnancy. Surgery is the primary treatment. Chemotherapy has an established role in loco-regionally advanced ...
Ozerdemoglu Remzi A - - 2003
STUDY DESIGN: A retrospective review with statistical correlations of 112 patients having both scoliosis and syringomyelia was performed. OBJECTIVE: To determine whether there were significant correlations between the type of scoliosis, location of the syrinx, size of the syrinx, clinical manifestation of the syrinx, and associated lesions such as cord ...
Tham B W L - - 2003
OBJECTIVE: To determine the incidence and trends of gestational trophoblastic disease in the Asian population of Northern England and North Wales.A prospective observational study. SETTING: Trophoblastic Screening and Treatment Centre, Weston Park Hospital. POPULATION: A total of 3660 women registered with gestational trophoblastic disease between 1991 and 1999. MAIN OUTCOME ...
Fisher R A - - 2003
The abnormal pregnancy hydatidiform mole (HM) can be classified as complete (CHM) or partial (PHM) on the basis of both morphology and genetic origin. PHM are diandric triploids while almost all CHM are androgenetic. Thus the characteristic trophoblastic hyperplasia seen in both CHM and PHM is usually associated with the ...
Hegab H M - - 2003
Circulating CA 125, CA 19-9, CA 15-3 and carcinoembryonic antigen (CEA) levels were studied in sixty patients with hydatidiform mole and in twenty normal pregnant women of a corresponding duration of pregnancy. Serum levels of CA 125, CA 15-3 and CEA are not affected by molar pregnancy. The mean level ...
Sebire N J - - 2003
Hydatidiform moles are genetically abnormal conceptions which are associated with an increased risk of development of persistent trophoblastic disease and choriocarcinoma. With the introduction of ultrasound examination as part of the routine clinical management of early pregnancy complications, the majority of molar pregnancies are now evaluated in the first trimester ...
Brivet M - - 2003
The patient was the first child of healthy consanguineous parents. She presented at birth with hypotonia, mild facial dysmorphism, periventricular cysts, marked metabolic acidosis, hyperlactacidemia with normal lactate/pyruvate molar ratios, normoglycemia, and normal ammonia. Hyperlactacidemia was severe (5-14 mmol/l) and not corrected with bicarbonate, thiamine (10 mg/d), 2-chloropropionate (100 mg/kg/d) ...
Matsui Hideo - - 2003
OBJECTIVE: This study analyzed the outcome of the first pregnancy following chemotherapy for gestational trophoblastic tumor (GTT). METHODS: A total of 387 patients with GTT (85 patients with high-risk GTT and 302 patients with low-risk GTT) underwent chemotherapy at Chiba University Hospital between 1974 and 2000. Of these patients, 130 ...
Fenner Kathrin - - 2003
The joint persistence (JP) quantifies the environmental persistence of a parent compound and a selection of relevant transformation products. Here, the importance as well as the uncertainty of the JP in comparison to the persistence of the parent compound alone (primary persistence, PP) are investigated. To demonstrate the effect of ...
Shioji Mitsunori - - 2003
Sonography has achieved a position of preeminence in the diagnostic evaluation of molar gestation. However, little information is available about the serial change of the transvaginal sonographic features of molar pregnancy. We describe a case of complete hydatidiform mole, and present serial transvaginal views taken during the early gestational period.
Garner Elizabeth I O - - 2003
BACKGROUND: Patients with arteriovenous malformations (AVMs) are at risk for significant vaginal hemorrhage, and are traditionally managed surgically. In the patient desiring future fertility, conservative management via selective arterial embolization is a reasonable option. Only a few cases have been previously reported of successful pregnancy after this procedure in the ...
Enoki Carla - - 2003
Early treatment for Class II malocclusion was undertaken with the objective of correcting skeletal disproportion by altering the growth pattern. A case of Class II, Division 1 malocclusion in the mixed dentition was corrected to Class I molar relationship using orthopedic cervical headgear, with nonextraction edgewise therapy. Cephalometric analysis indicated ...
Meinecke B - - 2003
Molar transformations of the bovine placenta are extremly rare phenomenona and the aetiology of this genuine placental disease is still unknown. In the present study, an uncommon case of a German Holstein Friesian foetus co-twinned with a hydatidiform mole is described. Cytogenetic and fluorescence in situ hybridization analysis of cell ...
Matsui Hideo - - 2003
BACKGROUND: The aim of this population-based retrospective study was to evaluate the trend in the incidence of molar pregnancy. METHODS: Questionnaires about the occurrence of hydatidiform mole were mailed to all clinics and hospitals in Chiba Prefecture between 1974 and 2000. The diagnosis of hydatidiform mole was based on the ...
Ozalp S - - 2003
This epidemiological study was performed in order to determine the frequency of hydatidiform mole (HM) in the rural part of Eski┼čehir, Turkey. Four mole cases and 6,274 pregnancies were determined in 2,032, women aged 15-49 which was 85% of the target population. Mean age, mean marriage age and mean marriage ...
Sebire N J - - 2003
OBJECTIVE: To determine pregnancy outcome, including the rate of repeat molar pregnancy, following histologically confirmed complete or partial hydatidiform mole. DESIGN: Retrospective review of a large supraregional database of registrations for gestational trophoblastic disease. SETTING: Supraregional Trophoblastic Disease Unit, London. SAMPLE: Women with pregnancies affected by complete or partial hydatidiform ...
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