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Results 101 - 150 of 1457
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Avagliano Laura - - 2010
Thrombosis of the umbilical vessels has been associated with conditions like fetal death, cerebral palsy, and severe fetal distress, which are common causes for litigation in today's obstetrics practice. Although different anatomical conditions of the umbilical cord as well as maternal or fetal pathologies are considered risk factors, the etiology ...
Hickey M - - 2010
Digit ratio (2D:4D) is widely used as a marker of prenatal androgen exposure. However, there are no published prospective studies where prenatal androgen exposure has been measured and correlated with digit ratio in adult life. We aimed to establish the prospective relationship between prenatal androgen exposure in the second and ...
Palomba S - - 2010
OBJECTIVE: To study the impedance to blood flow through the uterine artery in pregnant women with polycystic ovary syndrome (PCOS), and to evaluate its predictive value for adverse pregnancy and perinatal outcomes in this population. DESIGN: Prospective case-control study. SETTING: Academic Departments of Obstetrics and Gynaecology in Italy. POPULATION: Seventy-three ...
Patterson Tamula M - - 2010
We sought to validate center-specific published medians and estimate the effects of sonologist and Doppler measurement techniques on middle cerebral artery (MCA) peak systolic velocity (PSV) values. We studied 154 gravidas with normal singletons who underwent MCA PSV measurement at 18 to 35 weeks' gestation by one of three experienced ...
Akolekar Ranjit R Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, - - 2011
To determine if development of preeclampsia is preceded by altered maternal plasma P-selectin and if the levels are related with uterine artery pulsatility index. Plasma P-selectin and uterine artery pulsatility index were measured at 11-13 weeks in 121 cases that subsequently developed preeclampsia, 87 cases that developed gestational hypertension and ...
Barda G - - 2010
To evaluate the effect on the maternal and fetal circulation of progesterone administered to prevent preterm birth. We used an observational cohort study design. The study group included 44 women at 18-32 weeks' gestation who presented with an episode of preterm labor, with or without history of delivery before 34 ...
Plasencia W - - 2010
OBJECTIVES: To assess the influence of the presence of nuchal cord (NC) on the evaluation of the fetal ductus venosus flow velocity waveform (DV-FVW). METHODS: This prospective study included 1174 normal non-selected singleton pregnancies between 11 and 13 + 6 weeks' gestation. We recorded the presence or absence of NC ...
Tug Niyazi - - 2011
It was aimed to investigate the effects of short-term maternal fasting on fetal biophysical profile (BPP) scores and obstetric doppler indices. Thirty healthy uncomplicated singleton pregnancy cases were enrolled into the study. Fasting decreased BPP reversibly, but not to a level below 8/10. AFI, umbilical and MCA impedances were unchanged ...
Marcolin Alessandra C - - 2010
The aim of this study was to establish normal ranges of blood flow velocities and indices in the fetal ductus venosus (DV) during the second half of normal pregnancy. A Doppler study of 60 healthy pregnant women without fetal pathologies was performed during the second half of pregnancy. The peak ...
Leung K Y - - 2010
OBJECTIVE: To compare the predictive values of three ultrasonographic parameters: placental thickness (PT), fetal cardiothoracic ratio (CTR) and middle cerebral artery peak systolic velocity (MCA-PSV), alone or in combination, in pregnancies affected by homozygous alpha(0)-thalassemia at 12-20 weeks' gestation. METHODS: Pregnant women at risk of carrying a fetus affected by ...
Sherer David M - - 2010
Short umbilical cords are associated with fetal anomalies, often including those with decreased or absent fetal movement, fetal akinesia/hypokinesia sequence, and restrictive dermopathies and aneuploidy. In normal fetuses, abnormally short umbilical cords have been associated with an increased risk of umbilical vessel hematomas, thrombosis, rupture, thrombocytopenia, cord compression, variable fetal ...
Bano Shahina - - 2010
The aim of our study was to evaluate the usefulness of the pulsatility index (PI) of the umbilical artery (UA) and that of the fetal middle cerebral artery (MCA), as well as the ratio of the MCA PI to the UA PI (C/U ratio), in the diagnosis of small-for-gestational-age (SGA) ...
Arroyo Juan A - - 2010
Intrauterine growth restriction (IUGR) is a disease responsible for neonatal morbidity and mortality and perinatal death affecting 8% of all pregnancies. In sheep, IUGR that mimics the human IUGR disease closely can be brought on by environmental hyperthermia. Endothelial nitric oxidase synthase (eNOS) and nitric oxide (NO) are important in ...
Khalil Asma - - 2010
The aim of this study was to examine the potential effect of chorionic villus sampling (CVS) on placental perfusion by examining the change in uterine artery pulsatility index (PI) between the first and second trimesters of pregnancy. This was a prospective screening study for pregnancy complications which included measurement of ...
Lindqvist Pelle G - - 2010
OBJECTIVE: Growth arrest specific protein 6 (GAS6) is a newly discovered antiapoptotic protein related to cell survival. We hypothesized that GAS6 might be involved in the fetal adaptation to intrauterine growth restriction (IUGR). DESIGN: A nested case-control study. SETTING: A retrospective study of 25 small-for-gestational age and 36 appropriate-for-gestational age ...
Erdemoglu M - - 2010
The aim of the study was to determine the risk factors and perinatal outcomes of umbilical cord prolapse (UCP). This study was performed at Dicle University between January 2000 and December 2008 on 79 cases in which deliveries were complicated by umbilical cord prolapse. 0.36% of all deliveries were complicated ...
Sousa Tatiana - - 2010
Vitamin K1 is frequently used in the treatment and prevention of hypoprothrombinemia and hemorrhagic disease of the newborn. It also serves as an antidote to anticoagulants. Erythematous, indurated, pruritic plaques uncommonly occur in adults after intramuscular injection with vitamin K1. We present a case of a localized cutaneous reaction to ...
Becker Rolf - - 2010
OBJECTIVE: Our purpose was to assess the relation between the depth of notch in the uterine arteries at 20-23 weeks and the incidence and severity of subsequent pregnancy complications. METHODS: The Notch Index (NI) was defined as (C - D)/C, with C = postsystolic zenith and D = postsystolic nadir. ...
Dane Banu - - 2010
The aim of this study was to assess the correlation between first trimester maternal serum free beta-human chorionic gonadotropin (fBHCG), pregnancy-associated plasma protein A (PAPPA), second-trimester uterine artery (UA) Doppler measurements and adverse pregnancy outcomes. Serum levels of PAPPA and fBHCG were determined at the first trimester, and patients underwent ...
Umemura Kota - - 2010
Vaginal radical trachectomy (RT) ligates and cuts several arteries supplying the uterus. Changes of blood supply to the uterus in two patients who experienced pregnancy and delivery were studied by using 3-D CT scanning. Effects of changes of blood supply to the uterus on the pregnancy courses were also examined. ...
Wang Lina - - 2010
This is a prospective study of 182 women (38 yrs or younger) undergoing IVF-ET. Endometrial thickness, echo pattern and blood flow on transvaginal ultrasonography were recorded eight hours prior to hCG administration. The patients were divided into three groups: A (n = 10) with undetectable endometrial blood flow; B (n ...
Jacquemyn Y Y Department of Obstetrics and Gynaecology, Antwerp University Hospital UZA, Antwerpen. - - 2010
Inadequate trophoblast invasion of the spiral arteries in early pregnancy, an increased inflammatory response and changes in the immune answer to paternal antigens are considered aetiological factors in preeclampsia. Searching for factors related to these angiogenic, anti-angiogenic, immunologic and inflammatory mechanisms may provide methods to determine which patient will develop ...
Atkinson Andrew L AL Saba University School of Medicine, - - 2010
We report a 37 year old multi-parous lady, who in her third trimester of pregnancy, presented to the emergency room with acute diffuse abdominal pain and involuntary guarding. Findings on physical examination were consistent with peritonitis and a decision was made by the admitting team to perform an urgent laparotomy ...
de Melo Brena Carvalho Pinto BC Department of Maternal and Child Healthcare, Professor Fernando Figueira Maternal and Child Healthcare Institute (IMIP), Recife, PE, - - 2010
To assess uterine artery Doppler velocimetry performed in the third trimester of pregnancy in women with severe preeclampsia as a predictor of adverse postpartum outcome. A cohort study including 154 women, conducted in a teaching hospital in Recife, Brazil. Uterine artery Doppler was performed at admission to hospital and postpartum ...
Stampalija Tamara T Department of Obstetrics and Gynaecology, Children's Hospital "V. Buzzi", Via Castelvetro 32, Milano, Italy, - - 2010
Impaired placentation can cause some of the most important obstetrical complications such as pre-eclampsia and intrauterine growth restriction and has been linked to increased fetal morbidity and mortality. The failure to undergo physiological trophoblastic vascular changes is reflected by the high impedance to the blood flow at the level of ...
Alfirevic Zarko Z School of Reproductive and Developmental Medicine, Division of Perinatal and Reproductive Medicine, The University of Liverpool, First Floor, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, UK, L8 - - 2010
One of the main aims of routine antenatal care is to identify the 'at risk' fetus in order to apply clinical interventions which could result in reduced perinatal morbidity and mortality. Doppler ultrasound study of umbilical artery waveforms helps to identify the compromised fetus in 'high-risk' pregnancies and, therefore, deserves ...
Adamczak Joanna E - - 2010
Normal changes in blood pressure during pregnancy are well documented in the second and third trimesters. Little is known about first-trimester changes, particularly compared with preconceptional values. This knowledge might allow for early prediction of conditions such as preeclampsia or intrauterine growth restriction. Prior studies utilized a laboratory setting. We ...
Polisca A - - 2010
The aim of this work was to evaluate the hemodynamic changes in the utero-placental arterial vessels in rabbits (Orictolagus cuniculus) throughout pregnancy as well as those in the umbilical cord, aorta, and caudal vena cava of fetuses to establish their normal reference ranges for systolic peak velocity (SPV), end diastolic ...
To William W K - - 2009
OBJECTIVE: To compare Doppler measurements of umbilical arteries (UAs) and veins (UV) in diabetic and nondiabetic pregnancies near term. METHODS: Consecutive patients with gestational diabetes mellitus (GDM) were prospectively recruited from a regional obstetric service over an 18-month period. Doppler assessment of the UA and UV done within 10 days ...
Dicke Jeffrey M - - 2009
OBJECTIVE: The purpose of this study was to compare the screening efficiency of the umbilical artery systolic to diastolic ratio (S/D), pulsatility index (PI), and absent end-diastolic flow (AEDF) for adverse pregnancy outcomes and placental abnormalities in small for gestational age (SGA) fetuses. METHODS: We conducted a retrospective cohort study ...
Rizzo Giuseppe - - 2009
OBJECTIVE: The purpose of this study was to investigate the first-trimester placental volume and 3-dimensional (3D) power Doppler vascularization of pregnancies with low serum pregnancy-associated plasma protein A (PAPP-A) levels and to relate these findings to pregnancy outcomes. METHODS: Three-dimensional power Doppler sonography of the placenta was performed at gestational ...
Hill Martin - - 2010
The boost in placental production of CRH in late pregnancy is specific for human. CRH receptors are expressed in the fetal zone of the fetal adrenal (FZFA). Hence, we evaluated the associations between the steroid metabolome and gestational age (GA). The levels of 69 steroids and steroid polar conjugates such ...
Leung Tak Yeung - - 2009
OBJECTIVE: To estimate whether fetal bradycardia-to-delivery interval or decision-to-delivery interval was related to cord arterial pH according to different causes of fetal distress. METHODS: Women who delivered singleton neonates by urgent cesarean delivery because of intrapartum fetal bradycardia were retrospectively categorized into three groups according to the cause of fetal ...
Rafik Hamad Rangeen - - 2009
To assess left ventricular (LV) structure and function in preeclampsia, a serious vascular-related pregnancy disorder, by Doppler tissue imaging (DTI) in combination with the levels of cardiovascular biomarkers. Thirty-five pregnant women with preeclampsia and 30 with normal pregnancy, matched for age and gestational age were examined during pregnancy and 3-6 ...
Poon L C Y - - 2009
OBJECTIVES: To examine the performance of screening for hypertensive disorders in pregnancy at 11-13 weeks by a combination of the maternal history, uterine artery Doppler imaging and blood pressure. METHODS: This was a prospective screening study for pre-eclampsia (PE) requiring delivery before 34 weeks (early PE), late PE and gestational ...
Horton Amanda L - - 2010
We sought to determine the rate of adverse perinatal outcomes in pregnancies diagnosed with an isolated single umbilical artery (SUA). We performed a retrospective review comparing 68 pregnancies with an isolated SUA to 68 pregnancies with a three-vessel cord (3VC). Pregnancies with structural or karyotypic anomalies were excluded. Gestational age ...
Tantbirojn P - - 2009
OBJECTIVE: To evaluate umbilical cord abnormalities predisposing to mechanical cord compression and determine their relationship to adverse clinical outcomes and stasis-associated histologic changes in the placenta. METHODS: Placental slides of 224 singleton pregnancies with gross cord abnormality (true knots, long cords, nuchal/body cords, abnormal cord insertion, hypercoiled cords, narrow cords ...
Tasnim Nasira - - 2009
OBJECTIVE: To find out the predictive value of intrapartum Cardiotocograph (CTG) in terms of fetal acid base status at birth in women undergoing emergency caesarean section for a suboptimal CTG trace. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: At the MCH Centre, Pakistan Institute of Medical Sciences, Islamabad, ...
Maffei Pietro - - 2010
BACKGROUND: Only six women who were treated with somatostatin analogues (SSAs) throughout their pregnancies have been described so far. The influence of SSAs on the course of pregnancy and newborn outcomes remains largely unknown. Many aspects of SSAs pharmacokinetics in mother and foetus have not yet been defined. METHODS AND ...
Cruz-Martinez Rogelio - - 2009
Placental-associated diseases account for most cases of adverse perinatal outcome in developing countries. Uterine Doppler evaluation predicts most instances of early-onset preeclampsia and intrauterine growth restriction, but there is no evidence in favour of any prophylactic strategy in cases of an abnormal screening result. Umbilical artery Doppler investigation allows identifying ...
Hsu Te-Yao - - 2009
OBJECTIVE: To investigate the changes in Doppler indices of the fetal ductus venosus (DV) and umbilical artery (UMA) after amnioinfusion in pregnant women with preterm premature rupture of membranes (pPROM). Pregnancies with pPROM and severe oligohydramnios cause sequelae in newborns and mothers. MATERIALS AND METHODS: This cross-sectional study included a ...
Wang Kuo-Gon - - 2009
Abnormal umbilical artery flow with absent or reversed end-diastolic velocity (AREDV) during pregnancy is a strong indication of placental insufficiency. When AREDV occurs prenatally, a close follow-up or expeditious delivery should be contemplated. AREDV in the umbilical artery is associated with intraventricular hemorrhage, bronchopulmonary dysplasia, and perinatal mortality. It may ...
Anumba Dilly O C - - 2009
OBJECTIVES: Defective implantation is a mechanism for recurrent pregnancy loss (RPL). We sought to determine whether the serum expression of human relaxin-2 (RLX) is impaired in women with a history of RPL. STUDY DESIGN: Employing a prospective case-controlled design we studied 20 pregnant women with a history of RPL and ...
Dobrijević Lj J - - 2009
To examine fetal auditory perception in low- and high-risk pregnancies in period from 27 to 31 weeks gestational age with the aim to establish diagnostic parameters in prenatal detection of the degree of hearing development in a fetus. Method of prenatal hearing screening was applied on 80 women divided in ...
Torrance Helen L - - 2009
BACKGROUND: Fetal hypoxia is an important determinant of neonatal encephalopathy caused by birth asphyxia, in which hypoxia-induced free radical formation plays an important role. HYPOTHESIS: Maternal treatment with allopurinol, will cross the placenta during fetal hypoxia (primary outcome) and reduce S-100B and free radical formation (secondary outcome). METHODS: In a ...
Blanco P G - - 2009
The aim of this study was to describe the changes in the resistance index (RI) and systolic/diastolic ratio (S/D) of the uterine arteries during mid-pregnancy abortion induction in the dog. Sixteen 30-35 day pregnant bitches were randomly assigned to either a pharmacological protocol to interrupt gestation (n = 8) or ...
Tongsong Theera - - 2010
OBJECTIVE: To establish a reference range of splenic artery peak systolic velocity 1(SpA-PSV) in the normal singleton pregnancies (14-40 weeks). METHODS: A prospective descriptive study was conducted on uncomplicated singleton pregnancies with normal fetuses and accurate gestational age were recruited into the study. The Doppler measurements of SpA-PSV were performed ...
Gyselaers Wilfried - - 2009
Changes of Doppler velocity measurements of distinct hepatic vein (HV) Doppler wave components were evaluated during uncomplicated pregnancy (UP) as a reference to measurements in pre-eclampsia (PE). Women with UP (n = 13) were submitted to standardised duplex scanning of HV at 11 stages of pregnancy between 10 and 38 ...
Abd-El-Aal Diaa-Eldeen M - - 2009
OBJECTIVE: To assess the effect of short-term maternal fasting on uterine, umbilical, and middle cerebral artery Doppler indices, and on maternal serum glucose levels and fetal behavior. METHODS: Maternal serum glucose levels, fetal biophysical profiles, and uterine, umbilical, and middle cerebral artery Doppler indices were assessed in 110 healthy women ...
To William W K - - 2009
Objective. To compare Doppler measurements of umbilical arteries (UAs) and veins (UV) in diabetic and nondiabetic pregnancies near term. Methods. Consecutive patients with gestational diabetes mellitus (GDM) were prospectively recruited from a regional obstetric service over an 18-month period. Doppler assessment of the UA and UV done within 10 days ...
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