Search Results
Results 451 - 500 of 1457
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van der Heijden Olivier W H - - 2004
OBJECTIVE: The progressive increase in uterine blood flow (UBF) during pregnancy is accommodated by morphologic changes in the uterine artery (UA) in a process defined as arterial remodeling. This process is accompanied by changes in cytoskeletal architecture of the arterial smooth muscle cells (SMCs) and surrounding extracellular matrix (ECM). Aging ...
Carbillon L - - 2004
OBJECTIVE: Uterine artery flow velocity was prospectively assessed using Doppler ultrasound at 12-14 and 22-24 weeks of gestation in the prediction of subsequent complications related to uteroplacental insufficiency: preeclampsia, pregnancy-induced hypertension, fetal growth restriction, fetal death and placental abruption, and to elucidate its relationship with birth weight. METHODS: Uterine artery ...
Bats A-S - - 2004
OBJECTIVE: To evaluate the efficacy of a uniform management protocol in antiphospholipid-antibody-positive obstetric patients with at least one second- or third-trimester intra-uterine fetal death. STUDY DESIGN: A prospective study of 33 successive pregnancies in antiphospholipid-antibody-positive patients, diagnosed after an intra-uterine fetal death. The management included treatment by a combination of ...
Schwarze A - - 2005
AIM: The aim of this prospective study was to assess the role of uterine artery colour Doppler waveform analysis in the prediction of adverse pregnancy outcome such as preeclampsia, intrauterine growth retardation, placental abruption or a combination of outcome parameters. METHODS: Various uterine artery Doppler ultrasound parameters (RI>0.58, RI>0.7 and ...
Axt-Fliedner R - - 2005
AIM: The aim of this prospective study was to assess the role of uterine artery color Doppler waveform analysis in the prediction of adverse pregnancy outcome such as preeclampsia, intrauterine growth retardation, placental abruption or a combination of outcome parameters in risk pregnancies (n=52). METHODS: Various uterine artery Doppler ultrasound ...
McLean Lynn K - - 2004
OBJECTIVE: The purpose of this study was to determine the clinical outcome of isoimmunized pregnancies managed primarily by middle cerebral artery peak systolic velocity. STUDY DESIGN: A retrospective chart review was conducted of isoimmunized pregnancies that underwent ultrasound examinations from January 1, 2001, through May 1, 2003. Ultrasound reports, laboratory ...
Papageorghiou Aris T - - 2004
The complications of placental insufficiency, pre-eclampsia and fetal growth restriction (FGR) are major causes of perinatal as well as maternal morbidity and mortality. In normal pregnancy, impedance to flow in the uterine arteries decreases with gestation, and histopathological studies suggest that this is due to trophoblastic invasion of the spiral ...
Chanprapaph Pharuhas - - 2004
OBJECTIVE: To evaluate the validity of systolic/diastolic (S/D) ratio of the umbilical artery in predicting intrauterine growth restriction (IUGR). STUDY DESIGN: Diagnostic test study. SETTING: Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University. SUBJECTS: Two hundred and twelve singleton pregnancies between 30 and 42 weeks' gestation with clinical suspicion of ...
Spinillo Arsenio - - 2004
BACKGROUND: The role of antenatal risk factors associated with the occurrence of fetal growth restriction complicated by abnormal umbilical artery Doppler studies has not yet been studied extensively. We evaluated the role and the interactions of antenatal antecedents of fetal growth restriction complicated by abnormal umbilical artery end-diastolic velocities. METHODS: ...
Boulanger C - - 2004
OBJECTIVE: We report the case of a 36-yr-old woman with nesidioblastosis treated throughout pregnancy with high doses of octreotide. We studied the course of blood glucose, foetal growth and development. METHODS: Blood samples were obtained every month throughout pregnancy and taken at birth from the umbilical cord. Sonography was performed ...
Gratacós E - - 2004
OBJECTIVE: To evaluate the incidence and clinical relevance of intermittent absent and/or reversed diastolic flow on umbilical artery Doppler in different groups of monochorionic twin pregnancies. METHODS: This was a prospective study involving three groups of monochorionic pregnancies: Group 1: controls followed fortnightly from the first trimester (n = 80); ...
Scheier M - - 2004
OBJECTIVE: In red blood cell (RBC) isoimmunized pregnancies fetal anemia is associated with a hyperdynamic circulation. The aim of the present study was to examine further the possible value of fetal middle cerebral artery peak systolic velocity (MCA-PSV) in the management of affected pregnancies. METHODS: A reference range of fetal ...
Galia M - - 2004
We assessed the accuracy of voiding color Doppler ultrasonography (US) with echo enhancement for diagnosis or exclusion of vesicoureteral reflux (VUR) versus voiding cystourethrography (VCUG) and evaluated patient tolerance of the echo-enhancing agent. One hundred twenty-two patients (ages range, 1 month to 17 years) with 244 ureterorenal units underwent voiding ...
Van Schoubroeck D - - 2004
OBJECTIVE: Heavy bleeding in the late postpartum has, in some cases, been attributed to subinvolution of the placental bed and enhanced myometrial vascularity (EMV) as seen on color Doppler imaging. The aim of this study was to investigate the incidence and spontaneous evolution of areas of enhanced vascularization over the ...
Segata Maria - - 2004
PURPOSE OF REVIEW: The purpose of this review is to summarize recently published studies on noninvasive diagnosis of fetal anemia in order to give recommendations for the use of these new tools. RECENT FINDINGS: Red cell alloimmunization remains one of the most common causes of fetal anemia. Amniocentesis and cordocentesis ...
Aardema M W - - 2004
The 'classical' concept that pregnancy-induced hypertension (PIH) and pre-eclampsia (PE) primarily originate from defective placentation in early pregnancy has been challenged recently. There is growing evidence that other factors, including maternal predisposing conditions, also play a significant role in the pathophysiology of PIH and PE. The aim of the present ...
Raio Luigi - - 2004
OBJECTIVE: To explore the sonographic vascular architecture and the hyaluronan amount and distribution of umbilical cords of healthy and trisomy 21 fetuses in early gestation. MATERIAL AND METHODS: Umbilical cord sonographic morphology and morphometry of 112 consecutive normal fetuses and 11 trisomy 21 fetuses were assessed between 10 and 15 ...
Baytur Yesim Bulbul - - 2005
Dilatation of the fetal intra-abdominal umbilical vein is a rare entity. It is unclear whether prenatally diagnosed umbilical vein dilatation is associated with an increased risk of fetal anomalies or poor perinatal outcome. Umbilical artery waveform notching may be a predictor of cord abnormalities. It seems reasonable following the baby ...
Hilgers Rob H P - - 2004
To test whether membrane-bound angiotensin I-converting enzyme (t-ACE) is involved in arterial remodeling, we applied unilateral carotid artery (CA) ligation and studied uterine arteries (UA) before, during, and after pregnancy in t-ACE-/- and t-ACE+/+ mice. RESULTS- In CA of t-ACE-/- mice, blood pressure, outer diameter (D), and medial cross-sectional area ...
López-Quesada Eva - - 2004
OBJECTIVES: (a) To evaluate the predictive value of uterine Doppler velocimetry for pregnancy complications, (b) to study the relationship between abnormal uterine Doppler velocimetry and plasma homocysteine, and (c) to determine whether homocysteine measurement improves the predictive value of uterine Doppler screening. STUDY DESIGN: Prospective study including 94 pregnant women ...
Detti Laura - - 2004
The introduction of new techniques for evaluating fetal status, particularly fetuses at theoretical risk for hypoxic ischemic encephalopathy, requires the most rigorous evaluation before widespread clinical deployment. The considerations extend beyond clinical value to the significant medicolegal implications of a failure to predict or ascertain compromise. The attitudes to clinical ...
Simchen Michal J - - 2004
OBJECTIVE: Our aim was to study the hemodynamic effects of betamethasone on fetuses with intrauterine growth restriction (IUGR) with absent or reversed end-diastolic (ARED) umbilical artery flow. STUDY DESIGN: Color/pulsed Doppler waveforms were obtained before and after intramuscular injections of betamethasone in 19 consecutive fetuses with IUGR/ARED and 6 control ...
Descargues G - - 2004
BACKGROUND: The long-term effects of uterine artery embolization for the control of postpartum haemorrhage on menses, fertility and future pregnancy evolution have not been assessed. METHODS: Between November 1993 and July 1999, 31 women with obstetric haemorrhage underwent arterial embolization. Four patients underwent a hysterectomy. Gynaecological information on 25 of ...
Smith Simone A - - 2004
OBJECTIVES: The study was undertaken to obtain normal values for characteristics of the peripheral arterial pulse wave, in nonpregnant women and in pregnant women at three different stages of gestation, with two devices, to describe cardiovascular hemodynamic variables induced by pregnancy. STUDY DESIGN: Sixty pregnant women were enrolled in the ...
Baschat A A - - 2004
This article provides an opinion on a study of relationships between umbilical artery (UA) Doppler, ductus venosus (DV) Doppler, fetal heart rate variation, and perinatal outcome in preterm, intrauterine growth-restricted (IUGR) fetuses published in the same issue of this journal by Bilardo and coworkers. Recent evidence on venous Doppler surveillance ...
Kaufmann P - - 2004
In this second review, we describe the main morphological events which accompany the development of the fetoplacental vascular system throughout normal human pregnancy and summarize findings on the expression of angiogenic growth factors and their receptors. Fetoplacental vasculogenesis starts at day 21 after conception by formation of haemangioblastic cords. In ...
Mäkikallio K - - 2004
BACKGROUND: We hypothesized that impaired trophoblast invasion leads to umbilicoplacental blood flow disturbances that could be detected by Doppler ultrasonography during the first trimester of the pregnancy. METHODS: After successful fresh IVF or ICSI programme, 41 of 47 enrolled subjects were followed up every 1-2 weeks between weeks 6 and ...
Prefumo F - - 2004
BACKGROUND: Defective trophoblastic invasion in early pregnancy is involved in the pathogenesis of pre- eclampsia. This study investigates the relationship between Doppler assessment of uterine artery resistance and endovascular trophoblastic invasion in the first trimester of pregnancy. METHODS: Patients undergoing termination of pregnancy for non-medical reasons were categorized as having ...
Gudnasson Haraldur M - - 2004
BACKGROUND: Impaired trophoblast invasion is suggested as the main cause of reduced placental perfusion, which results in fetal growth restriction and preeclampsia. Immunological response against the invading tissue has been given as the explanation. Preeclampsia frequently recurs during the next pregnancy. Doppler ultrasound can predict increased vascular impedance in the ...
Axt-Fliedner R - - 2004
One main goal of antenatal care is to improve the outcome of pregnancy in terms of perinatal morbidity and perinatal mortality by identifying women at risk of complications such as preeclampsia, intrauterine growth retardation, placental abruption and intrauterine death. The association between pre-eclampsia, intrauterine growth retardation and increased uterine artery ...
Ertan A Kubilay - - 2004
OBJECTIVE: To study changes in uteroplacental and fetal circulation after maternal exercise in appropriate-for-gestational-age fetuses (AGA) and intrauterine-growth-retarded fetuses (IUGR). MATERIALS AND METHOD: 33 women with an uncomplicated course of pregnancy and ten women with IUGR were examined. Physical stress was caused through a bicycle ergometer with 1.25 W/kg maternal ...
Haberman Shoshana - - 2004
OBJECTIVE: To determine the value of Doppler measurements obtained by a new multigate Doppler modality, the spectral Doppler index mapping (SDIM) technique, to predict adverse outcome among pregnant women with normal conventional umbilical artery (UA) Doppler indices. DESIGN: A cross-sectional prospective cohort study. SUBJECTS: 183 women with well-dated singleton pregnancies ...
Gojnic M - - 2004
Myomas during pregnancy must be evaluated carefully, especially in relation to possible premature delivery or spontaneous miscarriage. We wanted to find out whether the addition of Doppler assessment could help in the management of these cases. We found that from all cases of myomas during pregnancy, the most common association ...
Prefumo F - - 2004
OBJECTIVES: To investigate the relationship between second-trimester uterine artery Doppler findings and parity in a large pregnant population. METHODS: Uterine artery Doppler studies were performed in all singleton pregnancies at 18-23 weeks of gestation. The mean uterine artery resistance index and the presence or absence of protodiastolic notches were recorded. ...
Spiropoulos K - - 2004
BACKGROUND: The body position may have an effect on gas exchange though the magnitude of this effect has not been studied thoroughly during the three trimesters of pregnancy. OBJECTIVES: This study analyzes the effect of body position change on arterial oxygen tension (PaO2) and arterial carbon dioxide tension (PaCO2) in ...
Wareing Mark M Maternal and Fetal Health Research Center, University of Manchester, St. Mary's Hospital, Manchester, UK. - - 2004
Our aim was to compare placental chorionic plate small artery function in normal pregnancies and those complicated by preeclampsia and intrauterine growth restriction. In particular we wished to test the hypothesis that the constrictive potential of placental small arteries is modified in compromised pregnancy. Biopsies were obtained from term placentas ...
Boito Simona M - - 2003
OBJECTIVES: To determine fetal liver volume and its relation with umbilical venous volume flow and maternal glycosylated haemoglobin (HbA1c) in pregnancies complicated by diabetes mellitus type I. DESIGN: A cross sectional matched control study. Obstetric out patient clinic, Erasmus MC-University Medical Centre, Rotterdam. POPULATION: Data from fetuses of diabetic women ...
Dib F R - - 2003
OBJECTIVES: To establish normal values for renal artery resistance index (RI) and pulsatility index (PI) during gestation and, by comparison with non-pregnant controls, to determine if pregnancy affects these indices. METHODS: This was a prospective longitudinal study involving 36 normal pregnant women who underwent a total of 280 examinations at ...
Kuczera Bartłomiej - - 2003
Vascularisation of an organ is an index of its metabolic activity. The suprarenal glands are of crucial importance in the development of pregnancy. No data were found by the authors to describe the volume of the human foetal suprarenal arteries throughout pregnancy. The study was designed to form a database ...
Makh D S - - 2003
OBJECTIVE: To evaluate the utility of middle cerebral artery (MCA) and umbilical artery (UA) Doppler to predict anemia in intrauterine growth restricted (IUGR) fetuses. METHODS: Fetuses with an abdominal circumference < 5th percentile had UA and MCA Doppler prior to delivery. The UA pulsatility index (PI), MCA PI, ratio between ...
Hamill Neil - - 2003
BACKGROUND: Chorioangiomas are benign vascular tumors of the placenta. Complications occur when their size exceeds 5 cm. CASE: We report the use of peak systolic velocity in the middle cerebral artery, fetal hemoglobin levels in maternal circulation, and maternal serum alpha-fetoprotein levels in the diagnosis and management of fetal anemia ...
Brawley L - - 2004
Protein restriction in rat pregnancy programmes the development of elevated systolic blood pressure and vascular dysfunction in the offspring. A recent study has shown that hypertension is reversed by maternal glycine supplementation. Whether this protective effect is exerted directly on the embryo and fetus, or indirectly via effects on the ...
Warnes K E - - 2003
While the impact of exogenous glucocorticoids on the fetal cardiovascular system has been well defined, relatively few studies have characterised the role of endogenous fetal glucocorticoids in the regulation of arterial blood pressure (BP) during late gestation. We have therefore infused metyrapone, an inhibitor of cortisol biosynthesis, into fetal sheep ...
Alshimmiri M M - - 2003
OBJECTIVES: To study the correlation of peak systolic velocity in the middle cerebral artery with hemoglobin concentration in fetuses at risk of anemia due to Rhesus isoimmunization. DESIGN: Peak systolic velocity of middle cerebral artery (MCA-PSV) was measured before 66 cordocentesis procedures in 20 isoimmunized fetuses. Reference values were derived ...
Barkehall-Thomas Andrea - - 2003
OBJECTIVES: It has been previously shown that glucocorticoids alter umbilical artery flow velocity waveforms in singleton pregnancies complicated by umbilical artery absent end diastolic flow. Whether similar effects are evident in multiple pregnancies where one fetus has umbilical artery absent end diastolic flow is not known. METHODS: Women with a ...
Smith Richard P - - 2003
OBJECTIVE: To determine whether fetal response to needling resembles the fetal 'brain sparing' response seen with hypoxaemia. DESIGN: Prospective observational study. SETTING: Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, London. POPULATION: Eighty-five pregnant women undergoing invasive procedures associated with fetal prenatal diagnosis and/or management. METHODS: The femoral artery ...
Vergani Patrizia - - 2003
OBJECTIVE: The study was undertaken to assess whether prenatal Doppler variables can identify cases of fetal growth restriction (FGR) approaching term who are at risk for adverse neonatal outcome. STUDY DESIGN: From a cohort of FGR cases delivered at >or=34 weeks, fetal biometry and pulsatility indices (PI) of fetal arteries ...
Li Hui - - 2003
BACKGROUND: An impaired placental circulation is involved in the mechanism of late fetal heart rate (FHR) decelerations. OBJECTIVES: To explore umbilical artery (UA) Doppler velocimetry changes in response to uterine contractions during the oxytocin challenge test (OCT) and assess the potentially clinical value of 'OCT Doppler velocimetry'. METHODS: 111 women ...
Hollis B - - 2003
OBJECTIVES: To determine reference values for first-trimester uterine artery resistance index (RI) in healthy pregnant women with uncomplicated pregnancies and to investigate the relationship between uterine artery Doppler indices and birth weight. METHODS: This was a cross-sectional study of 265 consecutive pregnant women attending routine ultrasound examination at 11-14 weeks' ...
Scharf Alexander - - 2003
The pathophysiologic continuum of poor uterine and placental blood flow associated with fetal growth restriction has to be considered the major cause of poor birth outcomes. The main attention in this context is drawn to the possibilities of an early diagnosis of imminent fetal compromise prior to and under delivery. ...
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