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Nair R R - - 2013
C+3953T IL-1 B single-nucleotide polymorphism (SNP) genotyping was carried out in 140 unrelated early pregnancy loss (EPL) patients and in 198 fertile healthy control women and in chorionic villous samples by PCR-RFLP. In Indian population, this is the first report on association of IL-1 B SNP C+3953T polymorphism and EPL.
Magdoud K - - 2013
Transforming growth factor β1 (TGF-beta-1) plays a significant role in pregnancy outcome. We investigated the association of TGFB1 exon 1 (rs1800471, rs1800470) and promoter region (rs1800469, rs1800468) polymorphisms with recurrent pregnancy loss (RPL) in 675 Tunisian women: 304 women with a history of three consecutive pregnancy losses of unknown etiology ...
Kim Ji Hyang - - 2013
OBJECTIVE: To investigate the association between one-carbon metabolism and recurrent pregnancy loss (RPL). One-carbon metabolism is important for maintaining pregnancy, and the enzymes codified by these genes are relevant to this metabolic pathway. DESIGN: Case-control study. SETTING: An urban university-based hospital in South Korea. PATIENT(S): A cohort of 353 RPL ...
Bonaventure Audrey - - 2013
PURPOSE: This study aimed to analyze the associations between childhood acute leukemia (AL) and maternal caffeinated beverage consumption during pregnancy, and to explore interactions between caffeinated and alcoholic beverage consumption and polymorphisms of enzymes involved in caffeine and ethanol metabolisms. METHODS: The data were generated by the French ESCALE study, ...
van Rij M C - - 2013
This study aims to give an overview of the number of prenatal tests for Huntington's disease (HD), test results, and pregnancy outcomes in the Netherlands between 1998 and 2008 and to compare them with available data from the period 1987-1997. A total of 126 couples underwent prenatal diagnosis (PND) on ...
Hönger G - - 2013
The aim of this study was to define the frequency and determinants of pregnancy-induced child-specific sensitization shortly after full-term delivery using sensitive single HLA-antigen beads (SAB) and high resolution HLA-typing of the mothers and their children (n = 301). A positive SAB result was defined by a background normalized ratio ...
Asgari Nooshin N Department of biology, Sciences and Research Branch Islamic Azad University, Tehran, - - 2013
Numerous lines of evidence implicate Apolipoprotein E (Apo E) in lipid metabolism during pregnancy. Hence, a role for its polymorphism has been envisaged in recurrent pregnancy loss (RPL) considering major structural and functional differences between different Apo E genotypes. A case control study of 81 women with two or more ...
DovĨ-Drnovšek Tadeja - - 2013
Immunoprophylaxis with IgG anti-D is a standard prevention of hemolytic disease of the fetus and newborn. Fetal Rhesus D (RhD) blood group genotyping from maternal plasma of RhD-negative pregnant women allows targeted prophylaxis with IgG anti-D in RhD-positive pregnancies only. We set up a reliable protocol for prenatal RHD genotyping. ...
Nair Rohini R - - 2012
Glutathione S-transferase theta 1 (GSTT1) and glutathione S-transferase Mu 1 (GSTM1) enzymes of the glutathione detoxification pathway protect the embryo from oxidative stress. This study investigated GSTT1 and GSTM1 in relation to their role in conferring genetic susceptibility to pregnancy loss. In a case-control study, 174 early pregnancy loss (EPL) ...
Grande M - - 2012
OBJECTIVE: This study aims to assess the suitability of non-invasive prenatal RHD genotyping in non-immunized midtrimester pregnant women from a mixed ethnic population, to prevent unnecessary anti-D immunoglobulin prophylaxis and to identify RHD variants METHODS: Rhesus D-negative pregnant women were offered fetal RHD genotyping at 24 gestational weeks. A total ...
Gleicher Norbert N Center for Human Reproduction, New York, NY 10021, USA. - - 2013
To investigate whether androgen conversion rates after supplementation with dehydroepiandrosterone (DHEA) differ, and whether differences between patients with diminished ovarian reserve (DOR) are predictive of pregnancy chances in association with in vitro fertilization (IVF). In a prospective cohort study we investigated 213 women with DOR, stratified for age (≤ 38 ...
Hur Jinhee - - 2012
Excessive iron consumption during pregnancy can lead to increased oxidative stress in the maternal body, which may result in adverse pregnancy outcomes. Glutathione S-transferases (GSTs) originate from a superfamily of detoxifying enzymes that play a role in reducing xenobiotic compounds and oxidative stress. The aim of this study was to ...
Le Toriellec Emilie - - 2012
BACKGROUND: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is due to maternal alloimmunization against fetal platelet (PLT) antigens. Antenatal management strategies have been developed to avoid complications such as intracranial hemorrhage. The aim of this study was to set up two reliable, noninvasive fetal genotyping assays to determine the fetal risk ...
Tang Ke-Qiong - - 2012
Progesterone receptor (PGR) and estrogen receptor alpha (ESRα), which mediate the biological effects of the steroid hormones progesterone and estrogen, play a central role in the establishment and maintenance of pregnancy. The objectives of this study were to detect bovine PGR and ESRα genes polymorphisms and analyze their relationships with ...
Muniz Ludmila - - 2012
Haplotypes formed by polymorphisms (T-786C, rs2070744; a variable number of tandem repeats in intron 4, and Glu298Asp, rs1799983) of the eNOS gene were associated previously with gestational hypertension (GH) and preeclampsia (PE). However, no study has explored the Tag SNPs rs743506 and rs7830 in these disorders. The aim of the ...
Parveen Farah - - 2012
OBJECTIVE: To determine association of cytokine gene polymorphism with risk for recurrent miscarriages (RM). DESIGN: Retrospective case-control study on northern Indian RM cases versus control subjects. SETTING: Medical facility. PATIENT(S): A total of 200 women with at least three unexplained spontaneous abortions before 20 weeks of gestation. INTERVENTION(S): Subjects were ...
Rezende Vania B - - 2012
Hypertension is the most common medical disorder in pregnancy, and a leading cause of maternal and neonatal morbidity and mortality. Vitamin D endocrine system has important influence on immune modulation and endothelial function, which play a role in preeclampsia (PE) and gestational hypertension (GH). Vitamin D receptor (VDR) is present ...
Nardi Fabiola da Silva - - 2012
PROBLEM: HLA-G expression is related as an immune modulator of fetal-maternal tolerance, and its levels was correlated with pregnancy outcome. In a case-control study, we investigate the association between the genetic variability of the HLA-G gene and serum levels of soluble HLA-G in cases of embryo implantation failure. METHOD OF ...
Loisel Dagan A DA Department of Human Genetics, The University of Chicago, 920 E 58th St., Chicago, IL 60637, - - 2013
The non-classical major histocompatibility complex molecule, human leukocyte antigen (HLA)-G, is thought to contribute to maternal immune tolerance and successful placentation during pregnancy. Genetic polymorphisms in HLA-G are known to influence expression levels as well as the relative expression of individual protein isoforms. As diminished or aberrant HLA-G expression patterns ...
Tyrrell Jessica J European Centre for Environment and Human Health, University of Exeter, The Knowledge Spa, Truro, - - 2012
Maternal smoking during pregnancy is associated with low birth weight. Common variation at rs1051730 is robustly associated with smoking quantity and was recently shown to influence smoking cessation during pregnancy, but its influence on birth weight is not clear. We aimed to investigate the association between this variant and birth ...
Zhang Youcheng - - 2012
The purpose of this research was to attempt a preliminary study of noninvasive prenatal diagnosis of Down syndrome in Southwest Chinese gravidas by using the plasma placental RNA allelic ratio. The genotypes of the single-nucleotide polymorphisms (SNPs) located in the transcribed regions of the gene PLAC4 were detected in population ...
Samli H - - 2012
Vascular endothelial growth factor (VEGF) regulates endothelial cell proliferation, migration and differentiation. VEGF plays a critical role in angiogenesis during placenta formation. We investigated whether VEGF gene polymorphisms are associated with recurrent pregnancy loss. Thirty-eight women with recurrent pregnancy loss and 30 control women with live-born children were recruited from ...
Thakur Geeta A - - 2012
Despite strong pharmacological evidence implicating the norepinephrine transporter in ADHD, genetic studies have yielded largely insignificant results. We tested the association between 30 tag SNPs within the SLC6A2 gene and ADHD, with stratification based on maternal smoking during pregnancy, an environmental factor strongly associated with ADHD. Children (6-12 years old) ...
Bonilla Carolina C School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom. - - 2012
Vitamin B-12 is essential for the development and maintenance of a healthy nervous system. Brain development occurs primarily in utero and early infancy, but the role of maternal vitamin B-12 status during pregnancy on offspring cognitive function is unclear. In this study we assessed the effect of vitamin B-12 status ...
Groves Allison K AK University of North Carolina at Chapel Hill, NC 27599, USA. - - 2012
Intimate partner violence (IPV) during pregnancy has been associated with multiple negative health outcomes including emotional distress during pregnancy. However, little is known about IPV during pregnancy and its association with emotional distress among South African women. The objectives of this study were to determine the prevalence of both emotional ...
Becker Jeroen H - - 2011
Objective. To evaluate the added value of the baseline T/QRS ratio to other known risk factors in predicting adverse outcome and interventions for suspected fetal distress. Design. Prospective cohort study. Setting. Three academic and six non-academic teaching hospitals in the Netherlands. Population. Laboring women with a high-risk cephalic singleton pregnancy ...
Bekkers Marga B M - - 2012
Previous studies have suggested possible adverse side-effects of maternal use of folic acid-containing supplements (FACSs) during pregnancy on wheeze and asthma in early childhood. We investigated the association between maternal use of FACSs and childhood respiratory health and atopy in the first 8 yrs of life. Data on maternal use ...
Helbig A - - 2011
Please cite this paper as: Helbig A, Kaasen A, Malt U, Haugen G. Psychological distress after recent detection of fetal malformation: short-term effect on second-trimester uteroplacental and fetoplacental circulation. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03155.x. We examined the short-term effect of severe maternal psychological distress on the placental circulation in second trimester ...
Lee Chee-Hong - - 2011
We report a woman presenting with respiratory failure due to a right-sided pleural effusion, lung metastases and lymphangitis carcinomatosis from advanced lung adenocarcinoma in the third trimester of pregnancy, who showed good response to EGFR tyrosine kinase inhibitor.
Courouble Patricia - - 2011
Extracorporeal membrane oxygenation (ECMO) is a technique that provides support to selected patients with severe respiratory failure. During the 2009 H1N1 influenza infection outbreak, ECMO was used with a good impact on survival for pregnant women, who are at higher risk of H1N1 influenza infection. However, there is little information ...
Oliveira Sergio M - - 2011
The gerbil female prostate is located paraurethrally and has all the histological components of the male prostate, like secretor epithelium and fibromuscular stroma. This gland, like the prostate in males, is targeted by testosterone action, which promotes morphofunctional development. Furthermore, estrogens are required to maintain the male and female prostate ...
Friedman Brooke E - - 2011
To investigate the relationship between air bubble position after blastocyst transfer (BT) and pregnancy rates (PRs). Retrospective cohort study. University-based infertility center. Three hundred fifteen consecutive nondonor BTs by a single provider. Catheters were loaded with 25 μL of culture media, 20 μL of air, 25 μL of media containing ...
Kansal Kalra Suleena - - 2011
To study the association of perinatal outcome and IVF transfer type in a group of infertility patients with standardized treatment and similar prognosis. Retrospective cohort study. University-based infertility center, January 1998 to June 2006. Two hundred eighteen IVF pregnancies after fresh embryo transfer (ET); 122 IVF pregnancies after frozen ET. ...
Sifer Christophe - - 2011
In this prospective observational study, the onset of a clinical pregnancy after elective single embryo transfer (eSET) was significantly associated with: 1) the woman's age as well as the number of good- and top-quality embryos; and 2) the day of the embryo transfer (day 3>day 2). Good-quality embryos had the ...
Wiener-Megnazi Zofnat - - 2011
To examine whether the oxidative status of an individual embryo before transfer may predict chances of implantation. A prospective laboratory study. An IVF unit in a university-affiliated hospital. One hundred thirty-three women undergoing IVF-ET treatment cycles. Before ET, 10 μL of embryo culture medium was retrieved individually from each embryo ...
Wininger J David - - 2011
To report a clinical pregnancy after rebiopsy and vitrification of blastocysts following allele dropout (ADO) of biopsied day 3 embryos. Case report. Private center. Thirty-year-old woman and her 33-year-old husband who carries the single-gene condition paraganglioma. In vitro fertilization with day 3 embryo biopsy-ET-blastocyst biopsy and vitrification-subsequent frozen ET cycle. ...
Bos-Mikich Adriana - - 2011
A common observation in oocyte in vitro maturation (IVM) cycles is poor embryo quality. However, no study was dedicated to assess zygote and early cleavage embryo quality in IVM cycles. The objective of this study is to analyze fertilization outcome, embryo development and the resulting pregnancy and births in unstimulated ...
Farhi Jacob - - 2010
To assess the effect of obesity on implantation rate, pregnancy rate and course of pregnancy in young women undergoing IVF in whom only high-quality embryos were transferred, a cohort study included women attending the IVF unit in 2006-2007 with favourable parameters to achieve pregnancy (<38years, fewer than three IVF cycles, ...
Asemota Obehi A - - 2011
To report the occurrence of Candida glabrata chorioamnionitis complicating an in vitro fertilization (IVF) pregnancy. Case report. University hospital. A 30-year-old woman, primagravida, with an IVF dichorionic-diamniotic pregnancy who presented at 15 weeks with vaginal bleeding. Before embryo transfer in next IVF cycle, vaginal culture from the patient revealed colonization ...
Benagiano Giuseppe - - 2010
Establishing the proportion of fertilized oocytes and early human embryos that proceed to term may help policy makers in their evaluation of when the life of a new human individual begins and in determining the nature of protection to be accorded to it. The rate of spontaneous abortions, although increasing ...
Orris John J - - 2010
to determine if embryo banking with PGS is more optimal than proceeding with PGS regardless of embryo number. patients were divided into 2 groups, group 1 were those that banked embryos and proceeded through another round of IVF prior to PGS, and group 2 underwent PGS regardless of embryo number. ...
Okohue J E - - 2010
BACKGROUND: The Human Fertilization and Embryology Authority is considering limiting the number of embryos that can be transferred to single embryo per cycle as has been done in several European countries, with the aim of reducing the rate of multiple pregnancies and its attendant complications following in vitro fertilization (IVF) ...
Shahine Lora K - - 2011
Day 2 embryo transfer has been suggested as a method to improve pregnancy rates in poor responders compared with day 3 transfer. Our prospective randomized controlled trial does not show a difference in outcomes based on day of embryo transfer.
Luke Barbara - - 2010
To evaluate the effect of embryo transfer number on singleton and twin pregnancy outcomes with one and two fetal heartbeats on early ultrasound, respectively. The study included 23,645 singleton and 14,083 twin live births from the SART-CORS Online database of assisted reproductive technology cycles for 2004-2006. The data were limited ...
Tsoumpou Ioanna - - 2011
To investigate the hypothesis that women achieving pregnancy after two or more failed embryo transfers (ETs) of good quality embryos have increased incidence of preeclamptic toxemia (PET) or fetal growth restriction (FGR) compared with those conceiving in the first ET after in vitro fertilization (IVF). Case-control study. Tertiary infertility center. ...
Martin J Ryan - - 2011
To compare the impact of mandated IVF insurance coverage on ET practices and resulting multiple pregnancy rates. Retrospective analysis of all fresh, nondonor IVF cycles performed in the United States in 2006. United States. A total of 91,753 fresh, nondonor IVF cycles in the United States. None. Pregnancy rate, live-birth ...
Schmidt M - - 2010
The aim of this study was to report from a larger study with pregnancy and delivery results after transfer of cloned transgenic/non-transgenic Large White or minipig embryos to Large White sow recipients. The effect of both total numbers of transferred embryos as well as site of their deposition (uni- vs. ...
Kahraman Semra - - 2010
The objective of this study was to compare the post-warming survival rates of biopsied and non-biopsied day-3 embryos vitrified on day 4 and to evaluate the clinical outcomes of following transfers. This study included 18 preimplantation genetic diagnosis (PGD) patients and 18 non-PGD patients treated between January 2005 and January ...
Makrakis Evangelos - - 2010
PURPOSE OF REVIEW: To update information on the findings of hysteroscopy in women with implantation failures after in-vitro fertilization (IVF) as well as on the effect of the procedure on subsequent pregnancy rates. RECENT FINDINGS: Information from three review publications indicates that the incidence of abnormal hysteroscopic findings in women ...
Goto Sakae - - 2011
To present an estimation of the pregnancy rate after IVF or intracytoplasmic sperm injection stratified by blastocyst morphology and age. Retrospective analysis. Private IVF clinic. A total of 1,488 single frozen-thawed blastocyst transfer cycles. All frozen-thawed blastocysts used in the study were obtained in the patients' first oocytes retrieval cycles. ...
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