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Results 301 - 350 of 1349
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Bloomfield Frank H - - 2013
Fetal growth is largely regulated by nutritional supply. The placenta is responsible for fetal nutrient supply for much of pregnancy, but in early pregnancy nutrition is histiotrophic. Both placental size and efficiency, and fetal growth, may be affected by maternal nutritional state before and during very early pregnancy. In contrast, ...
Haram Kjell - - 2013
The growth of the fetus, which is strongly associated with the outcome of pregnancy, reflects interplay of several physiological and pathological factors. The assessment of fetal growth is based on comparison of birthweight (BW) or estimated fetal weight (EFW) to standards which define reference ranges at a spectrum of gestational ...
Fung Alison M - - 2013
The objective of this study is to determine whether obstructive sleep apnea (OSA) is associated with reduced fetal growth, and whether nocturnal oxygen desaturation precipitates acute fetal heart rate changes. We performed a prospective observational study, screening 371 women in the second trimester for OSA symptoms. 41 subsequently underwent overnight ...
Talmor Alon - - 2013
The relationship between Doppler measurements, size and growth rate in fetal growth restriction has not been defined. We used functional linear discriminant analysis (FLDA) to investigate these parameters taking account of the difficulties inherent in exploring relationships between repeated observations from a small number of cases. In 40 fetuses with ...
Jabbari Hossein - - 2013
Maternal nutritional is the most important environmental factor influencing pregnancy outcome. While studies showed association between maternal iron-micronutrient deficiencies with pregnancy outcome, data examining impact of micronutrient supplementation on growth rate beyond birth are sparse. Present study examined the relationship between iron and multivitamins supplementation on growth rate of babies ...
Gokina Natalia I - - 2013
Decreased peroxisome proliferator-activated receptor gamma (PPARγ) activity is thought to have a major role in preeclampsia through abnormal placental development. However, the role of PPARγ in adaptation of the uteroplacental vasculature that may lead to placental hypoperfusion and fetal growth restriction during pregnancy is not known. Here, pregnant Sprague-Dawley rats ...
Awwad Johnny J Department of Obstetrics and Gynecology, American University of Beirut Medical Center, P.O. Box 113-6044, Beirut, - - 2013
Background. Desmoids are benign tumors, with local invasive features and no metastatic potential, which have rarely been described to be pregnancy associated. Case. We described the rapid growth of an anterior abdominal wall mass in a 40-year-old pregnant woman. Due to its close proximity to the enlarged uterus, it was ...
Singh Mandeep M Women's Hospital, Kensington Building, Leicester Royal Infirmary, Leicester LE1 5WW, - - 2013
Changes in circulating levels of maternal serum transforming growth factor beta-1 (TGF- β 1), collected from 98 women (AGA) at different gestational ages (10-38 weeks) were measured and comparisons were made between levels in pregnant and nonpregnant controls and also between 10 women with small-for-gestational age (SGA) and 7 with ...
Hromadnikova Ilona I Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, Ruska 87, 100 00 Prague, Czech - - 2013
The objective of the study was to identify the profile of circulating C19MC microRNAs (miR-516-5p, miR-517∗, miR-518b, miR-520a∗, miR-520h, miR-525, and miR-526a) in patients with established preeclampsia (n = 63), fetal growth restriction (n = 27), and gestational hypertension (n = 23). We examined the correlation between plasmatic concentrations and ...
Larkin Jacob J Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, - - 2013
Intrauterine mammalian development depends on the preservation of placental function. The expression of the protein N-myc downstream-regulated gene 1 (NDRG1) is increased in placentas of human pregnancies affected by fetal growth restriction and in hypoxic primary human trophoblasts, where NDRG1 attenuates cell injury. We sought to assess the function of ...
Liberato Selma C SC Menzies School of Health Research, Charles Darwin University, Darwin, - - 2013
Maternal diet during pregnancy is one of the most important factors associated with adequate fetal growth. There are many complications associated with fetal growth restriction that lead to lifelong effects. The aim of this review was to describe the studies examining the effects of protein energy supplementation during pregnancy on ...
Alers Nicole O NO The Ritchie Centre, Monash Institute of Medical Research, Monash University, Clayton, Victoria, - - 2013
Fetal growth restriction complicates about 5% of pregnancies and is commonly caused by placental dysfunction. It is associated with increased risks of perinatal mortality and short-term and long-term morbidity, such as cerebral palsy. Chronic in utero hypoxaemia, inflammation and oxidative stress are likely culprits contributing to the long-term neurological sequelae ...
Whitehead Clare - - 2013
Hypoxia in utero can lead to stillbirth and severe perinatal injury. While current prenatal tests can identify fetuses that are hypoxic, none can determine the severity of hypoxia/acidemia. We hypothesized a hypoxic/acidemic fetus would up-regulate and release hypoxia-induced mRNA from the fetoplacental unit into the maternal circulation, where they can ...
Ciavattini Andrea A Woman's Health Sciences Department, Faculty of Medicine, Polytechnic University of Marche, Via Corridoni 11, 60123 Ancona, - - 2013
Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically apparent in a large part of reproductive aged women. Clinically, they present with a variety of symptoms: excessive menstrual bleeding, dysmenorrhoea and intermenstrual bleeding, chronic pelvic pain, and pressure symptoms such as a sensation of bloatedness, increased urinary ...
Laskowska Marzena M Department of Obstetrics and Perinatology, Medical University of Lublin, ul. Jaczewskiego 8, Lublin, Poland. - - 2013
The aim of our study was to investigate the association between homocysteine and asymmetric dimethylarginine in preeclamptic women with and without intrauterine growth restriction compared with normal healthy uncomplicated pregnancies and normotensive pregnancies complicated by idiopathic isolated intrauterine fetal growth restriction. The maternal serum homocysteine and asymmetric dimethylarginine concentrations were ...
Zanello Margherita - - 2012
OBJECTIVE: To evaluate the alteration in epidermal growth factor-like domain 7 (EGFL7) mRNA expression in maternal blood from pregnancies affected by early-onset intrauterine growth restriction (IUGR) at 20-24 weeks. METHOD: Case-control study encompassing six women with pregnancies affected by IUGR (cases) matched in a 1 : 7 ratio for gestational age and fetal ...
Hernandez Teri L TL Division of Endocrinology, Metabolism, and Diabetes, University of Colorado, Anschutz Medical Campus, Aurora, Colorado 80045, USA. - - 2013
The power of continuous glucose monitoring system (CGMS) technology to profile glycemic patterns throughout a 24-h period has benefited the care of individuals with diabetes mellitus for over 10 years. Recently, this technology has been utilized to better understand glucose patterns in pregnancy, especially as they relate to abnormal fetal ...
Mullins Edward - - 2012
Fetal growth restriction (FGR) is a major complication of pregnancy with unknown etiology which results in marked fetal, neonatal and long-term morbidity, and mortality. FGR is likely to result from suboptimal placental implantation and perturbed immunological interactions. The diagnostic criteria for FGR vary between studies and the condition often occurs ...
Snijder Claudia A - - 2013
Background: Prenatal exposure to bisphenol A (BPA) has been associated with adverse birth outcomes, but findings of previous studies have been inconsistent.Objective: We investigated the relation of prenatal BPA exposure with intrauterine growth and evaluated the effect of the number of measurements per subject on observed associations.Methods: This study was ...
de Steenwinkel Florentien D O - - 2012
BACKGROUND: High rheumatoid arthritis (RA) disease activity during pregnancy is associated with a lower birth weight. Active RA is characterised by high circulating levels of cytokines, which can mediate placental growth and remodelling. OBJECTIVES: To assess the influence of maternal serum cytokine levels on birth weight in RA pregnancy. METHODS: ...
Gindes L - - 2012
Purpose: To identify the fetal anal canal and sphincter using 3-dimensional (3 D) ultrasound. Materials and Methods: 3 D volumes of the fetal pelvis were acquired prospectively in 52 fetuses between 10 and 39 gestational weeks. A standard method for evaluating the fetal anal canal and sphincter was developed. Measurements of mucosal ...
Al-Khan A - - 2012
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, five of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of clinical ...
Ahmed M S MS Department of Obstetrics and Gynaecology, University of Texas Medical Branch, Galveston, TX, - - 2013
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, four of which are summarized in this report. These workshops related to various aspects of placental biology: 1) epigenetics and imprinting in the ...
Adami Fausto - - 2012
Abstract We report on a young pregnant woman developing distal leg edema and hypoalbuminemia, who was lately diagnosed with AL amyloidosis. Fetal growth retardation led to a caesarian section in the 27th week of gestation. A live birth healthy female, 710 g weight, was admitted to the neonatal intensive care unit ...
Van Scheltinga Josien A Terwisscha - - 2012
OBJECTIVE: Guidelines define hypertension diagnosed before 20 weeks gestation as chronic hypertension (CH) and thereafter as gestational hypertension (GH). We tested the hypothesis whether hypertension diagnosed before 20 weeks is preceded by CH and if pregnancy outcome depends on the time of onset of hypertension. DESIGN: Retrospective cohort study. SETTING: ...
Aye I L M H - - 2012
Adiponectin has well-established insulin-sensitizing effects in non-pregnant individuals. Pregnant women who are obese or have gestational diabetes typically have low circulating levels of adiponectin, which is associated with increased fetal growth. Lean women, on the other hand, have high circulating levels of adiponectin. As a result, maternal serum adiponectin is ...
Kim Hye Won - - 2012
SCOPE: We examined the effect of paternal folate deficiency on the folate content, the percentage of 5-methycytosine (percentage of 5-mC) in the total DNA, and the protein expression of insulin-like growth factor-2 (IGF-2) in the fetal whole brain. METHODS AND RESULTS: Rats were mated after males were fed a folic ...
Barrientos Gabriela - - 2012
Early pregnancy is characterized by decidual adaption to the developing embryo involving angiogenesis and vascular growth. Failure of decidual vascular expansion is linked to diseases of pregnancy. Dendritic cells (DC) have been associated with vascular growth during early gestation, though it is unknown whether their capacity to modulate angiogenesis is ...
Baken L - - 2012
Introduction: Aneuploidy is associated with fetal growth restriction already present from the first trimester of pregnancy onwards. With three-dimensional (3D) ultrasound it is possible to measure Embryonic Volume (EV). The innovative 3D Virtual-Reality (VR) approach is a fast and reliable way to measure EV. The relative increase in EV is ...
Bamberg Christian - - 2012
Macrosomia is diagnosed when excessive intrauterine fetal growth occurs and the birth weight surpasses an established limit. The causes and risk factors for fetal macrosomia are diverse. Pregnancies with fetal macrosomia are considered high risk and require intensive antenatal care. Prenatal ultrasound appears to be the best method for performing ...
Kovo M - - 2012
OBJECTIVE: Our objective was to investigate the placental component in early- and late-onset fetal growth restriction (FGR) compared to placentas from neonates appropriate for gestational age (AGA). STUDY DESIGN: Placentas from normotensive women who gave birth at 24-42 weeks to neonates with a birth-weight below the 10th percentile (FGR group), ...
Shimon Ginath - - 2012
Abstract Objective: To describe the normal appearance and the growth of the fetal vermis, pons and midline brainstem by ultrasound from 18 weeks of gestation to term in order to produce developmental nomograms. Methods: Serial ultrasound examinations of the fetal brain were performed in 21 fetuses between 18 and 39 ...
van Uitert Evelyne M - - 2012
Worldwide periconceptional folic acid supplement use is recommended to prevent neural tube defects. This also stimulated research on maternal folate status in association with fetal growth, an important predictor of perinatal and future development and health. We provide an overview of literature on associations between maternal folate status during pregnancy ...
Ribeiro Aa - - 2012
The luteal phase on pregnant and non-pregnant bitches is characteristic of this species and resembles significantly with respect to the growth pattern and luteal regression. Histological and immunostaining studies of the corpus luteum (CL) may help to elucidate differences between the CL of pregnant and non-pregnant bitches. The purpose of ...
Goeritz F - - 2012
Assisted reproduction technologies are essential for propagating endangered wild felids. Artificial insemination (AI) has been reported in several wild feline species, but pregnancy rates are low, partially owing to failures of current hormonal stimulation protocols. Therefore, this study describes the application of reliable methods to monitor ovarian activity and the ...
Reynolds Simone A - - 2012
Evidence suggests that in response to in utero insults, male versus female infants have greater disadvantages in pregnancy outcome. In addition, there is a growing body of evidence suggesting that there is a sex-specific fetal response to maternal disease during pregnancy. We considered that a sex-specific relationship may exist between ...
Bazer Fuller W - - 2012
I developed a passion for reproductive biology when taking a course in Physiology of Reproduction at Louisiana State University while preparing to apply for Veterinary School at Texas A&M University. My career path changed. I entered graduate school, obtained a Ph.D. and have enjoyed an academic career conducting research in ...
Karthikeyan T - - 2012
The Gestational Age (GA) is frequently over or under estimated, as the conventional gestational estimation is based on the Last Menstrual Period (LMP) and on ultrasonography (USG). Many people are unaware of their LMP and irregular menstruations and USG is bound to have a bias, thereby posing difficulties in the ...
Goetzinger Katherine R KR MSCI, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes-Jewish Hospital Plaza, Campus Box 8064, St Louis, MO 63110, USA. - - 2012
To estimate the association between isolated second-trimester short femur length and fetal growth restriction as well as other adverse perinatal outcomes. We conducted a retrospective cohort study of patients with singleton gestations presenting for sonography between 16 and 24 weeks' gestation from 1990 to 2009. Cases of aneuploidy, skeletal dysplasia, ...
de Carvalho Ana Alice Vidal - - 2012
OBJECTIVE: To investigate the association between the midtrimester presence of short femur and short humerus and intrauterine growth restriction. METHODS: This retrospective study included ultrasound examinations of 1043 fetuses. Fetuses with normal-length bones were compared with fetuses that had femoral or humeral lengths below the 5(th) percentile for gestational age ...
Larsson Anders - - 2012
Background: Insulin-like growth factor (IGF) binding protein-1 (IGFBP-1) is the main binder of IGFs in secretory endometrium and decidualized stromal endometrial cells and IGFBP-1 has been shown to modulate IGF bioactivities and influence fetal growth. To be able to evaluate IGFBP-1 values during pregnancy it is important to establish normal ...
Cappelletti M - - 2012
INTRODUCTION: The state of activation of dendritic cells (DCs) at the feto-maternal interface critically contributes to optimal decidual immune responses needed to support fetal-placental development. We recently demonstrated that during healthy pregnancy also peripheral blood DCs (PBDCs), which are easily accessible, are activated as well. In this study, to investigate ...
Schoner Katharina - - 2012
OBJECTIVE: Fetal pathology aims to recognize syndromal patterns of anomalies for goal-directed mutation analyses, genetic counseling, and early prenatal diagnosis in consecutive pregnancies. Here, we report on five fetuses with Peters' plus syndrome (PPS) from two distinct families aborted after prenatal ultrasound diagnosis of hydrocephaly. METHOD: We performed fetal autopsies ...
Kulandavelu Shathiyah - - 2012
It is not known whether eNOS deficiency in the mother or the conceptus (ie, placenta and fetus) causes fetal growth restriction in mice lacking the endothelial NO synthase gene (eNOS knockout [KO]). We hypothesized that eNOS sustains fetal growth by maintaining low fetoplacental vascular tone and promoting fetoplacental vascularity and ...
Jeric Milka - - 2012
PURPOSE: Maternal nutritional status is one of the most important factors of fetal growth and development. Consequently, the currently increasing prevalence of underweight women worldwide has come in the focus of interest of perinatal medicine. The aim of the study was to assess the effect of low pre-pregnancy body mass ...
Rifai Kinan - - 2012
Abstract Objective. Focal nodular hyperplasia (FNH) is a benign liver tumor considered to develop under the influence of estrogens. Whether women with known FNH are at higher risk of growth progression and complications during pregnancy is still controversially discussed. The authors investigated the growth pattern of FNH during pregnancy and ...
Grazul-Bilska Anna T AT Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University, Fargo, North Dakota, USA. - - 2013
The origin of embryos including those created through assisted reproductive technologies might have profound effects on placental and fetal development, possibly leading to compromised pregnancies associated with poor placental development. To determine the effects of embryo origin on fetal size, and maternal and fetal placental cellular proliferation and global methylation, ...
Gootwine E - - 2012
A meta-analysis was performed to study the relationship between ovine fetal BW and body length during the last month of pregnancy in sheep gestated under normal conditions and under different natural and experimental maternal- placental- and fetal- directed constraints. Means of crown-rump length (CRL) and BW records, as well as ...
Spinillo Arsenio - - 2012
OBJECTIVE: The objective of the study was to evaluate the association between placental histological patterns and umbilical artery (UA) Doppler velocimetry in pregnancies complicated by fetal growth restriction (FGR). METHODS: A cohort of 126 FGR pregnancies was followed according to a standard protocol. Placental lesions were diagnosed according to consensus ...
Mayeur Sylvain - - 2012
Low birth weight is associated with an increased risk to develop type 2 diabetes and metabolic diseases. The placental capacity to supply nutrients and oxygen to the fetus represents the main determiner of fetal growth. However, few studies have investigated the effects of maternal diet on the placenta. We explored ...
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