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Ribeiro Aa - - 2012
The luteal phase on pregnant and non-pregnant bitches is characteristic of this species and resembles significantly with respect to the growth pattern and luteal regression. Histological and immunostaining studies of the corpus luteum (CL) may help to elucidate differences between the CL of pregnant and non-pregnant bitches. The purpose of ...
Goeritz F - - 2012
Assisted reproduction technologies are essential for propagating endangered wild felids. Artificial insemination (AI) has been reported in several wild feline species, but pregnancy rates are low, partially owing to failures of current hormonal stimulation protocols. Therefore, this study describes the application of reliable methods to monitor ovarian activity and the ...
Reynolds Simone A - - 2012
Evidence suggests that in response to in utero insults, male versus female infants have greater disadvantages in pregnancy outcome. In addition, there is a growing body of evidence suggesting that there is a sex-specific fetal response to maternal disease during pregnancy. We considered that a sex-specific relationship may exist between ...
Bazer Fuller W - - 2012
I developed a passion for reproductive biology when taking a course in Physiology of Reproduction at Louisiana State University while preparing to apply for Veterinary School at Texas A&M University. My career path changed. I entered graduate school, obtained a Ph.D. and have enjoyed an academic career conducting research in ...
Karthikeyan T - - 2012
The Gestational Age (GA) is frequently over or under estimated, as the conventional gestational estimation is based on the Last Menstrual Period (LMP) and on ultrasonography (USG). Many people are unaware of their LMP and irregular menstruations and USG is bound to have a bias, thereby posing difficulties in the ...
Goetzinger Katherine R KR MSCI, Department of Obstetrics and Gynecology, Washington University School of Medicine, 4911 Barnes-Jewish Hospital Plaza, Campus Box 8064, St Louis, MO 63110, USA. - - 2012
To estimate the association between isolated second-trimester short femur length and fetal growth restriction as well as other adverse perinatal outcomes. We conducted a retrospective cohort study of patients with singleton gestations presenting for sonography between 16 and 24 weeks' gestation from 1990 to 2009. Cases of aneuploidy, skeletal dysplasia, ...
de Carvalho Ana Alice Vidal - - 2012
OBJECTIVE: To investigate the association between the midtrimester presence of short femur and short humerus and intrauterine growth restriction. METHODS: This retrospective study included ultrasound examinations of 1043 fetuses. Fetuses with normal-length bones were compared with fetuses that had femoral or humeral lengths below the 5(th) percentile for gestational age ...
Larsson Anders - - 2012
Background: Insulin-like growth factor (IGF) binding protein-1 (IGFBP-1) is the main binder of IGFs in secretory endometrium and decidualized stromal endometrial cells and IGFBP-1 has been shown to modulate IGF bioactivities and influence fetal growth. To be able to evaluate IGFBP-1 values during pregnancy it is important to establish normal ...
Cappelletti M - - 2012
INTRODUCTION: The state of activation of dendritic cells (DCs) at the feto-maternal interface critically contributes to optimal decidual immune responses needed to support fetal-placental development. We recently demonstrated that during healthy pregnancy also peripheral blood DCs (PBDCs), which are easily accessible, are activated as well. In this study, to investigate ...
Schoner Katharina - - 2012
OBJECTIVE: Fetal pathology aims to recognize syndromal patterns of anomalies for goal-directed mutation analyses, genetic counseling, and early prenatal diagnosis in consecutive pregnancies. Here, we report on five fetuses with Peters' plus syndrome (PPS) from two distinct families aborted after prenatal ultrasound diagnosis of hydrocephaly. METHOD: We performed fetal autopsies ...
Kulandavelu Shathiyah - - 2012
It is not known whether eNOS deficiency in the mother or the conceptus (ie, placenta and fetus) causes fetal growth restriction in mice lacking the endothelial NO synthase gene (eNOS knockout [KO]). We hypothesized that eNOS sustains fetal growth by maintaining low fetoplacental vascular tone and promoting fetoplacental vascularity and ...
Jeric Milka - - 2012
PURPOSE: Maternal nutritional status is one of the most important factors of fetal growth and development. Consequently, the currently increasing prevalence of underweight women worldwide has come in the focus of interest of perinatal medicine. The aim of the study was to assess the effect of low pre-pregnancy body mass ...
Rifai Kinan - - 2012
Abstract Objective. Focal nodular hyperplasia (FNH) is a benign liver tumor considered to develop under the influence of estrogens. Whether women with known FNH are at higher risk of growth progression and complications during pregnancy is still controversially discussed. The authors investigated the growth pattern of FNH during pregnancy and ...
Grazul-Bilska Anna T AT Department of Animal Sciences, Center for Nutrition and Pregnancy, North Dakota State University, Fargo, North Dakota, USA. - - 2013
The origin of embryos including those created through assisted reproductive technologies might have profound effects on placental and fetal development, possibly leading to compromised pregnancies associated with poor placental development. To determine the effects of embryo origin on fetal size, and maternal and fetal placental cellular proliferation and global methylation, ...
Gootwine E - - 2012
A meta-analysis was performed to study the relationship between ovine fetal BW and body length during the last month of pregnancy in sheep gestated under normal conditions and under different natural and experimental maternal- placental- and fetal- directed constraints. Means of crown-rump length (CRL) and BW records, as well as ...
Spinillo Arsenio - - 2012
OBJECTIVE: The objective of the study was to evaluate the association between placental histological patterns and umbilical artery (UA) Doppler velocimetry in pregnancies complicated by fetal growth restriction (FGR). METHODS: A cohort of 126 FGR pregnancies was followed according to a standard protocol. Placental lesions were diagnosed according to consensus ...
Mayeur Sylvain - - 2012
Low birth weight is associated with an increased risk to develop type 2 diabetes and metabolic diseases. The placental capacity to supply nutrients and oxygen to the fetus represents the main determiner of fetal growth. However, few studies have investigated the effects of maternal diet on the placenta. We explored ...
Goetzinger K R - - 2013
To evaluate the performance of clinical estimation of fetal weight as a screening test for fetal growth disorders and then to estimate the effect of maternal body mass index (BMI) on its screening efficiency. This was a retrospective cohort study of patients referred for third trimester ultrasound for the indication ...
Luria Oded - - 2012
OBJECTIVES: To investigate the role of three-dimensional (3D) power Doppler ultrasonography in the assessment of fetal growth-restriction (FGR) with various degrees of severity and onset, and compare the results with the analysis of two-dimensional (2D) Doppler. STUDY DESIGN: Vascular indices extracted from 3D Doppler measurements of the placenta were compared ...
Himes K P KP Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, - - 2013
Monoallelic expression of imprinted genes, including ones solely expressed in the placenta, is essential for normal placental development and fetal growth. To better understand the role of placental imprinting in placental development and fetal growth, we examined conceptuses developing in the absence of maternally derived DNA (cytosine-5-)-methyltransferase 1o (DNMT1o). Absence ...
Ergaz Zivanit - - 2012
High sucrose low copper diet induces fetal growth restriction in the three strains of the Cohen diabetic rats: an inbred copper deficient resistant (CDr), an inbred copper deficient sensitive (CDs that become diabetic on high sucrose low copper diet -HSD) and an outbred Wistar derived Sabra rats. Although those growth ...
Unterscheider Julia - - 2012
OBJECTIVE: To identify maternal and pregnancy-related physiological and pathological variables associated with fetal growth and birthweight in Ireland and to develop customized birthweight centile charts for the Irish population that will aid in appropriate identification and selection of growth-restricted fetuses requiring increased antenatal surveillance. STUDY DESIGN: Prospectively collected outcome data ...
McDonald Thomas J TJ Department of Obstetrics and Gynecology, Center for Pregnancy and Newborn Research, University of Texas Health Sciences Center, San Antonio, TX 78229, USA. - - 2013
Mechanisms linking maternal nutrient restriction (MNR) to intra-uterine growth restriction (IUGR) and programming of adult disease remain to be established. The impact of controlled MNR on maternal and fetal amino acid metabolism has not been studied in non-human primates. We hypothesised that MNR in pregnant baboons decreases fetal amino acid ...
Walsh Jennifer M - - 2012
OBJECTIVE: To prospectively examine the prevalence of hypovitaminosis D in pregnancy and to correlate maternal and fetal vitamin D to fetal anthropometry. DESIGN: A prospective cohort study. SETTING: Tertiary referral maternity hospital. PATIENT(S): Sixty pregnant women. INTERVENTION(S): Serum 25-hydroxyvitamin D (25OHD) was measured in early pregnancy, at 28 weeks, and ...
Singh-Jagatia Pritpal - - 2012
The musculoskeletal function of vitamin D has been well defined, prompting the population to supplement with vitamin D and calcium to maximise bone growth. However the role of vitamin D in pregnancy has not been systematically studied and is permeated with continuing controversy regarding the cause and effect relationship of ...
Elmadfa Ibrahim - - 2012
Vitamins are essential nutrients for many body functions and particularly important during growth. Adequate supply in pregnancy and in early infancy is therefore crucial, but there is still a lack of knowledge about the needed amounts of vitamins of children older than six months and also during pregnancy. Recommendations for ...
Tung Elena - - 2012
Growth hormone (GH) is important in maternal adaptation to pregnancy, and maternal circulating GH concentrations are reduced in human growth-restricted pregnancies. In the pig, maternal GH treatment throughout early-mid pregnancy increases fetal growth, despite constraining effects of adolescent and primiparous pregnancy, high litter size and restricted maternal nutrition. Since GH ...
Menai Mehdi - - 2012
The objective of this study is to investigate the potential effect of maternal environmental cadmium (Cd) exposure on birth weight and fetal growth restriction (FGR). A total of 901 pregnant women from the EDEN cohort study were enrolled from two maternity units. Blood Cd was measured at mid-pregnancy and associations ...
Tan Yang - - 2012
Several epidemiological investigations, including previous work by our laboratory, indicate that maternal caffeine consumption is associated with intrauterine growth retardation and impaired fetal length growth. Skeletal development is critical for length growth. In the present study, our goals were to determine the effects of prenatal caffeine exposures on fetal skeletal ...
Woolnough C - - 2012
Placental development requires coordinated angiogenesis regulated by multiple factors including angiopoietins. Previously we demonstrated that the concentration of Angiopoietin-2 (Ang-2) in the sera of women rises markedly in pregnancy in early gestation. This increase is reduced in pregnancies subsequently complicated by intrauterine growth restriction (IUGR). We now show that the ...
Cecati Monia - - 2012
Abstract Objective: The neurotrophin family comprises molecules involved in growth, differentiation, survival, regeneration, normal functions of the neuronal system, and in angiogenesis. We have investigated the expression pattern of neurotrophic signaling molecules in pregnancies complicated by elevated liver enzyme, and low platelet (HELLP) syndrome and intrauterine growth restriction (IUGR). Methods: ...
Constant Marc - - 2012
Introduction: The purpose of this study was to obtain precise knowledge of fetal biometric measurements, in particular crown-rump length (CRL). Our results have been carefully compared to equations found in the literature. Materials and Methods: Single-operator measurements of 2,123 spontaneous pregnancies from a general French population provided new statistical relationships ...
Papapostolou Thalis - - 2012
Abstract Objective: To describe associations among maternal/gestational/neonatal characteristics and midpregnancy amniotic fluid concentrations of the main angiogenic markers vascular endothelial growth factor (VEGF) and placental growth factor (PlGF). Methods: In a cohort of 206 normal full-term pregnancies, midpregnancy amniotic fluid VEGF and PlGF reference values were recorded. Possible associations among ...
Walsh Jennifer M - - 2012
Evidence for a role of vitamin D in maintaining normal glucose homeostasis is inconclusive. We sought to clarify the relationship between maternal and fetal insulin resistance and vitamin D status. This is a prospective cohort study of 60 caucasian pregnant women. Concentrations of 25-hydroxyvitamin D (25-OHD), glucose, insulin, and leptin ...
Corcoran Jemma J - - 2012
Context:Discrete regulation of the uterine and placental vasculatures is an important feature of uteroplacental perfusion and pregnancy success because appropriate maternal/fetal exchange of nutrients and gases is crucial for normal fetal growth. Placental vasculature lacks autonomic innervation so tone is controlled by locally derived vasoactive factors. IGF-I, which is produced ...
Brouillet S - - 2012
Identifiable causes of fetal growth restriction (FGR) account for 30 % of cases, but the remainders are idiopathic and are frequently associated with placental dysfunction. We have shown that the angiogenic factor endocrine gland-derived VEGF (EG-VEGF) and its receptors, prokineticin receptor 1 (PROKR1) and 2, (1) are abundantly expressed in human ...
Shavit Tal - - 2012
Abstract Objectives: Infants with intrauterine growth restriction (IUGR) have increased morbidity and mortality. The decision whether to induce labor at term or to expectantly manage these pregnancies is controversial. The aim of this study was to assess the outcomes of these two management strategies in term pregnancies. Study design: This ...
- - 2012
PROFFERED PAPERS Growth cessation is not the necessary norm during the final weeks of gestation Amanda Mummert(1), Michelle Lampl(1) & Philippe Jeanty(2) (1)Department of Anthropology, Emory University, Atlanta, GA, USA (2)Women's Ultrasound, Nashville, TN, USA Background: The cessation of growth in late gestation is considered to be a universal consequence ...
Bedaiwy Mohamed A - - 2012
To measure amniotic fluid levels of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and transforming growth factor (TGF)-beta2 and to characterize their levels with respect to advancing gestational age and pregnancy-related complications. Amniotic fluid was collected from a total of 37 patients, 2 of whom had twin ...
Thompson Jennifer L - - 2012
Fetal growth restriction is a complex problem in modern obstetrics. It is a condition of suboptimal fetal growth based on a genetically predetermined potential and affects approximately 5% to 10% of pregnancies. It is traditionally defined as an estimated fetal weight less than the 10th percentile. Those pregnancies that are ...
Vaughan Owen R - - 2012
Stresses during pregnancy that increase maternal glucocorticoids reduce birth weight in several species. However, the role of natural glucocorticoids in the mother in fetal acquisition of nutrients for growth remains unknown. This study aimed to determine whether fetal growth was reduced as a consequence of altered amino acid supply when ...
Kawakita Tetsuya - - 2012
Fetal growth restriction (FGR) is frequently associated with uteroplacental insufficiency. Placental lakes are avillous spaces filled with maternal venous blood that usually do not compromise the pregnancy outcome; however, a few reports describe FGR in association with placental lakes. Reversed middle cerebral artery (MCA) end-diastolic flow is a rare event ...
Zollner Ursula - - 2012
Abstract Pregnancies that occur after infertility treatment, particularly after assisted reproduction, constitute high-risk pregnancies. Occurrences of conditions such as high blood pressure, preeclampsia, growth retardations and bleeding are higher in comparison with the norm of spontaneously entered pregnancies. The rate of premature births and the frequency of intrauterine deaths are ...
Pillay Priya - - 2012
The present study was conducted to compare the gravidogram and ultrasound in the detection of intrauterine growth restriction. This study was conducted in the Department of Obstetrics and Gynecology, Voluntary Health Services, Chennai (TN) from August 2007-May 2009. The study included 321 women with singleton pregnancy in a longitudinal lie. ...
Frederice Claudia Pignatti - - 2012
Aim:  To evaluate pelvic floor muscle (PFM) function and its association with urinary symptoms in the third trimester of pregnancy. Material and Methods:  A cross-sectional study was conducted among 91 nulliparous women at 30-34 weeks of pregnancy. PFM was evaluated by surface electromyography (sEMG) and manual muscle testing, while urinary symptoms ...
Thame M - - 2012
To describe a series of studies conducted which investigated maternal nutrition and its effect on birth outcome. Seven hundred and twelve women attending their first antenatal clinic visit at the University Hospital of the West Indies were invited to join a prospective study. The women were followed throughout their pregnancies ...
Dastjerdi Marzieh Vahid - - 2012
To determine whether the phosphodiesterase type 5 inhibitor, Sildenafil citrate, affects uteroplacental perfusion. Based on a randomized double-blinded and placebo-controlled trial, forty one pregnant women with documented intrauterine growth retardation at 24-37 weeks of gestation were evaluated for the effect of a single dose of Sildenafil citrate on uteroplacental circulation ...
Yusuf Kamran - - 2012
Abstract Objective: Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are associated with abnormal placentation. Heme oxygenase (HO) and carbon monoxide (CO) are involved in normal placental development and function and vasomotor control in the placenta. The objective of our study was to measure CO levels, as assessed by carboxyhemoglobin (COHb) ...
Clayton Douglass B - - 2012
Prenatal ultrasound is an integral part of caring for pregnant women in the United States. Although surprisingly few data exist to support the clinical benefit of screening ultrasound during pregnancy, its use continues to rise. Urologic anomalies are among the most commonly identified, with overall detection sensitivity approaching 90%. Prenatal ...
Ueda Yusuke - - 2012
Whether to manage placenta previa percreta surgically or conservatively has been a controversial issue. A 30-year-old woman with placenta percreta with bladder involvement was treated conservatively. A planned cesarean section was performed at 33 weeks' gestation. A 1768-g female infant was delivered through a transverse fundal uterine incision with the placenta ...
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