Search Results
Results 301 - 350 of 857
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Schmidt Peter - - 2007
INTRODUCTION: First-trimester screening according to Nicolaides uses maternal age to obtain a common background risk for trisomy 21. The likelihood ratios by nuchal translucency, free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A are not with respect to maternal age. It was the aim of this study to investigate if likelihood ...
Johnson Hope L - - 2007
Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider's ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in ...
Maher Jane Maree - - 2007
The visibility of pregnancy in contemporary societies through various forms of medical imaging has often been interpreted by feminist critics as negative for the autonomy and experience of pregnant women. Here, I consider the representation of pregnancy in Virginia Woolf's novel, Orlando, and Sally Potter's film of the same name ...
Valinen Yrtti - - 2007
OBJECTIVE: The purpose of this study was to compare the efficacy of both separate and combined maternal serum testing and fetal nuchal translucency measurement in the first trimester screening for Down syndrome in northern Finland. STUDY DESIGN: The following screening tests were evaluated: measurement of nuchal translucency (NT) alone; serum ...
Gallot D - - 2007
OBJECTIVES: To describe the true incidence, prenatal detection rate and fetal outcome of congenital diaphragmatic hernia (CDH) in a systematically registered population over an 18-year period and to determine any change in trends over time. METHODS: This was a retrospective study of all cases of CDH registered in the Central-Eastern ...
Wiwanitkit Viroj - - 2007
Urine pregnancy diagnostic test is easily available. It is a requirement of the screening program for Myanmar workers who pursue employment in Thailand. Only a few studies have estimated population pregnancy rates using objective and laboratory-based criteria. Here, the authors performed a study on laboratory-measured pregnancy rates among Myanmar workers ...
Au W Y - - 2007
Increasing numbers of successful pregnancies are reported in recipients of allogeneic hemopoietic stem cell transplantation (HSCT). These may occur naturally, or more commonly, through assisted reproduction. The pregnancy outcomes are usually normal. There are currently no guidelines on the prenatal management of pregnancies involving HSCT recipients. HSCT recipients are unique ...
Misra A A Ophthalmology Department, Addenbrookes Hospital, Cambridge, UK. - - 2008
To investigate whether current UK retinopathy of prematurity (ROP) screening guidelines miss the early development of pre-threshold type 1 ROP in some neonates born small for gestational age (SGA) and consider if the guidelines should be changed. Data were collected on neonates of < or =31 completed weeks gestation and/or ...
Lurie Samuel - - 2008
OBJECTIVE: To establish leukocyte count and leukocyte differential percentiles in normal uncomplicated pregnancy. STUDY DESIGN: This retrospective longitudinal study was performed in an outpatient facility for routine antenatal care. The study population comprised of 726 healthy women from the 5th to the 41st week of pregnancy. Altogether, there were 1749 ...
Cowans Nicholas J - - 2007
OBJECTIVES: To evaluate whether first-trimester levels of PAPP-A and serum free-beta-human chorionic gonadotrophin (free beta-hCG) vary with maternal blood group and rhesus status and to assess whether this has implications for first-trimester screening for chromosomal anomalies. METHODS: Blood group and rhesus status information was extracted from birth records for women ...
Morris J K - - 2007
Two equations are given to estimate the risk of a woman having a Down's syndrome pregnancy according to maternal age: one for use in estimating antenatal screening performance and the other for use in estimating an individual woman's risk of having an affected pregnancy. Because Down's syndrome pregnancies have an ...
Morris J K - - 2007
OBJECTIVES: It is widely thought that correlations between screening markers will tend to degrade screening performance. We performed a computer simulation study to investigate the quantitative effect of correlations between two markers on screening performance, using prenatal screening for Down's syndrome as an example, although the results apply generally. METHODS: ...
Palomaki Glenn E - - 2007
Prenatal screening for Down syndrome in the late first trimester involves the measurement of maternal serum markers and the fetal ultrasound marker, nuchal translucency (NT). In addition to the established first trimester maternal serum markers, pregnancy-associated plasma protein-A (PAPP-A), and the free beta-subunit of hCG (free beta), studies have indicated ...
Christiansen Michael - - 2007
BACKGROUND: Human placental lactogen (hPL) is synthesised by the placenta and found in maternal serum. We analysed the potential of hPL as a first-trimester maternal serum-screening marker for fetal Down syndrome (DS). MATERIALS AND METHODS: hPL was quantified by ELISA in 47 DS pregnancies and 136 controls in gestational weeks ...
- - 2007
In the last decade, numerous markers and strategies for Down syndrome screening have been developed. Algorithms that combine ultrasound and serum markers in the first and second trimesters have been evaluated. Furthermore, the practice of using age cutoffs to determine whether women should be offered screening or invasive diagnostic testing ...
Celentano Claudio - - 2007
OBJECTIVE: To investigate the relationship between maternal serum screening markers and pregnancy outcome in fetuses with cystic hygroma at 15-18 weeks of gestation. STUDY DESIGN: We retrospectively reviewed case-notes of 34 consecutive singleton fetuses with cystic hygroma referred at 15-18 weeks of gestation. All cases had maternal blood sampled for ...
Chueh Ho-Yen - - 2007
BACKGROUND: To assess pre- and post-procedural maternal anxiety about nuchal translucency thickness screening for Down syndrome in the first trimester of pregnancy, and the psychological impact of positive screening results. METHODS: A total of 172 women whose screens were positive for excess fetal nuchal translucency thickness, and 180 women whose ...
Quinton Ann E AE Discipline of Obstetrics and Gynaecology, The University of Sydney, Nepean Hospital, Penrith, NSW, Australia. - - 2007
To develop normal ranges of endothelial function in normal human pregnancy to use as a screening test for preeclampsia. In this longitudinal study, women were studied five times during pregnancy and once postpartum using flow-mediated dilatation (FMD). FMD is a noninvasive ultrasound technique used to assess endothelial function. Healthy nonpregnant ...
McGovern Peter G - - 2007
We investigated the prevalence of abnormal screening results (questionnaire and testing for other causes of oligo-ovulation, male or tubal factor infertility) in a group of 1,313 oligo-ovulatory women (included and excluded subjects) whose condition was screened for inclusion in the Pregnancy in Polycystic Ovary Syndrome trial, a multicenter clinical trial ...
Ramos-Corpas Domingo - - 2006
AIM: The aim of the present study is to determine whether the use of population parameters derived from meta-analysis produces better test characteristics in the first-trimester combined screening than those obtained from large single studies, when screening for Down syndrome (DS) in singleton pregnancies. METHODS: Retrospective analysis was done on ...
Kadir R A - - 2006
A pilot study was conducted over a 6-month period to evaluate antenatal screening for factor XI (FXI) deficiency amongst Ashkenazi Jewish women booking for their pregnancy in a single obstetric unit. Fifty-four women of Ashkenazi Jewish origin were recruited during their visit for the routine first trimester ultrasound scan. They ...
Hellmeyer L - - 2006
The objective of this study was to prospectively investigate the effect of pregnancy on biochemical markers of bone turnover in healthy pregnant women. During the course of our longitudinal study, biochemical markers of bone remodeling were measured in all three trimester of pregnancy (first trimester: 12.5+/-1.8 SD, second trimester: 21.6+/-1 ...
Sumeksri Permsak - - 2006
OBJECTIVE: To assess the prevalence of GDM in pregnant women aged 30 to 34 years old who were screened by glucose challenge test (GCT) at Phramongkutklao Hospital. MATERIAL AND METHOD: The cross-sectional data were collected from 1332 pregnant women aged between 30-34 years who attended the antenatal care clinic and ...
Su L L - - 2006
Antepartum foetal monitoring is crucial for the detection of foetuses at risk so that timely intervention can improve the perinatal outcome. The evidence underlying the most common modalities of antepartum foetal monitoring used are appraised and presented in this article. Foetal movement chart should be used in high-risk pregnancies but ...
Laigaard Jennie - - 2006
BACKGROUND: A Disintegrin And Metalloprotease 12 (ADAM 12) is a glycoprotein synthesised by placenta and it has been shown to be a potential first-trimester maternal serum marker for Down syndrome (DS) in two small series. Here we analyse further, the potential of ADAM 12 as a marker for DS in ...
Konialis Christopher P - - 2007
OBJECTIVE: The implementation and evaluation of a proposed wide-scale prenatal screening strategy, based on DNA isolated from dried blood spots in the first trimester of pregnancy, for the early detection of pregnancies at risk for cystic fibrosis (CF). METHODS: The screening was performed in conjunction with routine biochemical marker screening ...
Rissanen Anne - - 2007
OBJECTIVE: To evaluate whether first trimester screening markers are altered in pregnancies affected both by other chromosomal defects than trisomy 21 and structural anomalies and whether it is possible to detect these pregnancies by combined ultrasound and biochemical screening test. METHODS: Altogether 4,776 singleton pregnancies underwent first trimester screening. Of ...
Nabi Bidhendi Gholamreza - - 2007
This research demonstrates the quick guthion monitoring with the help of a sensitive method called fast Fourier transformation continuous cyclic voltammetry (FFTCV). Fortunately, FFTCV illustrates the benefits of precision, determination speed, cost-effectiveness, accuracy and simplicity, in comparison with formerly reported techniques. In particular, this method was applied to a gold ...
Wald Nicholas J - - 2006
OBJECTIVE: To compare the Integrated test in three policies for prenatal Down syndrome screening: Integrated screening for all women, sequential screening (first-trimester tests allowing early completion of screening for high-risk pregnancies), and Contingent screening (early completion of screening for high- and low-risk pregnancies). DESIGN AND METHODS: Estimation of detection rates ...
Craig Wendy Y - - 2006
BACKGROUND: Smith-Lemli-Opitz syndrome (SLOS) is a rare hereditary disorder of cholesterol metabolism. We examine the feasibility of identifying SLOS as a part of a routine prenatal screening and evaluate diagnostic testing in maternal urine (or serum), in addition to amniotic fluid. METHODS: Our SLOS risk algorithm utilized three Down syndrome ...
Schielen P C J I - - 2006
OBJECTIVES: This is the first report on the results of a first-trimester combined-test screening programme in the Netherlands in a multi-centre routine clinical setting. METHODS: Between July 2002 and May 2004, blood samples were taken from subjects in 44 centres in the Netherlands and sent to our laboratory to assay ...
Palomaki Glenn E - - 2006
OBJECTIVES: To confirm that measuring pregnancy-associated plasma protein-A (PAPP-A) in both first- and second-trimester serum samples improves Down syndrome screening. METHODS: We selected paired first- and second-trimester stored serum samples from 34 Down syndrome pregnancies (cases) and 514 unaffected pregnancies (controls) and tested the second-trimester samples for PAPP-A and dimeric ...
Lambert-Messerlian G - - 2006
OBJECTIVE: To determine whether first- and second-trimester Down syndrome screening markers and screen-positive rates are altered in pregnancies conceived using assisted reproductive technologies (ARTs). METHODS: ART pregnancies in the multicenter FASTER trial were identified. Marker levels were evaluated for five types of ART: in vitro fertilization with ovulation induction (IVF-OI), ...
Laigaard Jennie - - 2006
BACKGROUND: Maternal serum ADAM12 is reduced, on average, in early first-trimester Down and Edwards' syndrome pregnancies but the extent of reduction declines with gestation. Here we study levels at 9-12 weeks when the marker might be used concurrently with other established markers. METHODS: Samples from 16 Down and 2 Edwards' ...
Crane Elizabeth - - 2006
The risk of having a pregnancy with Down syndrome increases with maternal age. The percentage of all births in England and Wales to mothers aged 35 and over increased from 9% in 1989 to 19% in 2003. A 51% increase in the numbers of pregnancies with Down syndrome has been ...
Barsoom Michael J - - 2006
Severe preeclampsia rarely occurs prior to 20 weeks of gestation except in pregnancies with triploidy. The patient reported herein is a 29-year-old primigravida who developed severe preeclampsia at 20 weeks of gestation. Evaluation of the pregnancy demonstrated a markedly abnormal quadruple screen. Amniocentesis demonstrated a fetus with triploidy, despite a ...
Wang Yuan-Yuan - - 2006
OBJECTIVES: To compare the performance of double screening (measuring maternal serum levels of alpha-fetoprotein [AFP] and total beta-human chorionic gonadotrophin [hCG] as markers for Down syndrome) with that of triple screening (also measuring levels of unconjugated estriol [uE3]) in the second trimester of pregnancy, and to compare ethnic variance between ...
Wald Nicholas J - - 2006
OBJECTIVE: To examine the performance of Integrated Down syndrome screening (first- and second-trimester measurements integrated into a single screening test) when ratios of the levels of the same serum markers measured in both these trimesters (cross-trimester ratios) are added as new screening markers. METHODS: Using data from Serum Urine and ...
Gyselaers W J A - - 2006
OBJECTIVE: To design a trisomy 21 screening protocol for sequential triage in the first trimester, and to evaluate whether it reduces the need for advanced ultrasound scanning to such an extent that this could be dealt with by a limited number of well-trained sonographers only. METHODS: Screening results of 31 ...
McPherson B - - 2006
OBJECTIVE: Click-evoked otoacoustic emissions (CEOAEs) are widely used in universal neonatal hearing screening programs. A common finding in many such programs is a relatively high false-positive rate. This is often due to infant physiological noise adversely affecting the emission recording, leading to a "refer" screening outcome. In an attempt to ...
Weisz Boaz - - 2006
Since the introduction of antenatal serum screening for Down's syndrome (DS) more than two decades ago, several screening approaches have been utilized in routine clinical practice. The current DS screening strategies involve mid-trimester serum biochemistry tests, first trimester tests combining sonographic markers and serum biochemistry and integration of first and ...
O'Leary Peter - - 2006
OBJECTIVE: This study assessed fetal outcomes for pregnancies identified at increased risk for Down syndrome by first-trimester combined ultrasound examination and maternal serum biochemistry screening. METHODS: First-trimester combined screening data were obtained from ultrasound clinics across Western Australia between August 2001 and October 2003. Prenatal screening data were linked with ...
Lawson Karen L - - 2006
OBJECTIVE: The purpose of this study was to examine whether maternal serum screening (MSS) is associated with lower maternal attachment to pregnancy. METHODS: One hundred one pregnant women identified as at risk for fetal anomaly due to advanced maternal age completed a survey targeting their decisions regarding prenatal testing and ...
Varma Rajesh - - 2006
Recent research has suggested that women who experience preterm delivery (PTD) may be identified earlier in pregnancy and before onset of symptoms. Interventions commenced at this earlier asymptomatic stage may offer an opportunity to prevent PTD or lengthen gestation sufficiently to reduce adverse perinatal outcome. Our objective was to examine ...
Cooke Deirdre M - - 2006
This paper reports on the construct validity (scale design and convergent validity) and ecological validity of the Occupational Therapy Adult Perceptual Screening Test (OT-APST). The performance of 208 participants following stroke on the OT-APST and a reference tool (either the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) or the LOTCA-Geriatric version ...
Xia Yan-ping - - 2006
To investigate the efficiency of maternal serum triple screening for the genetic abnormality in second-trimester and the morbidity of adverse pregnancy outcome in false positive results of the test. A total of 4,680 pregnant women with singleton pregnancies assigned in Obs & Gyn Hospital, Fudan University, underwent triple screening test ...
Jones N - - 2006
To investigate asymptomatic vagino-rectal carriage of group B streptococcus (GBS) in pregnant women. Women in the final trimester of pregnancy were recruited. A single vagino-rectal swab was taken, with consent, for culture of GBS. Two microbiological methods for isolation of GBS from vagino-rectal swabs were compared. The distribution of capsular ...
Ip Wan Yim - - 2006
The GHQ-12 is a widely used instrument designed to screen for psychological disturbance (defined as the inability to carry out normal psychological functions and/or the emergence of new distressing phenomena), in a wide variety of clinical groups. The Chinese version of the GHQ-12 is widely used in Hong Kong to ...
Dacus John - - 2006
The cost effectiveness of prenatal screening for cystic fibrosis needs to be reexamined. This will require further study. At the time prenatal screening for CF carrier status was initiated, newborn screening for cystic fibrosis was not commonly available. The benefit of screening in our population was detection of 68 female ...
Whittle W - - 2006
Serious placental insufficiency results in perinatal death or preterm birth from ischemic-thrombotic pathology, a process which has its origins in placental maldevelopment in the first trimester. A proportion of at-risk pregnancies may be identified from abnormalities in first or second trimester serum screening data, uterine artery Doppler waveforms or placental ...
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