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Ippolito Danielle L DL Department of Clinical Investigation (D.L.I.) and Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology (M.A.L., S.K.F.-N.), Madigan Army Medical Center, Tacoma, Washington USA; Department of Obstetrics and Gynecology, Naval Medical Center, Portsmouth, Virginia USA (J.E.B.); and Department of Obstetrics and Gynecology, University of Arkansas for the Medical Sciences, Little Rock, Arkansas USA - - 2014
The objectives of this systematic review were to examine the reproducibility of sonographic estimates of amniotic fluid volume (AFV) in twin pregnancies, compare the association of sonographic estimates of AFV with dye-determined AFV, and correlate AFV with antepartum, intrapartum, and perinatal outcomes in twin pregnancies. Studies were included if they ...
Stirrup O T OT MRC Clinical Trials Unit at UCL, University College London, London, - - 2014
To generate reference charts for expected fetal growth in dichorionic diamniotic (DCDA) and monochorionic diamniotic (MCDA) twin pregnancies and to compare these with those from singleton pregnancies. This was a retrospective study of biometric measurements from serial ultrasound examinations of twin pregnancies in the second and third trimesters, from 14 ...
Aurioles-Garibay Alma A Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Md., - - 2014
Objective: To examine the association between an umbilical artery notch and fetal deterioration in monochorionic/monoamniotic (MC/MA) twins. Methods: Six MC/MA twin pregnancies were admitted at 24-28 weeks of gestation for close fetal surveillance until elective delivery at 32 weeks or earlier in the presence of signs of fetal deterioration. Ultrasound ...
Hyman Jordana H JH Department of Obstetrics and Gynecology, MUHC Reproductive Center F6.58, Royal Victoria Hospital, McGill University, 687 Pine Ave.West, Montreal, QC, H3A1A1, - - 2014
This case reports the first twin live births achieved in a woman with a serum FSH of such magnitude -80 IU/L, after following early hCG administration in natural cycle in vitro fertilization (IVF). Case report. A 27-year-old with 2 years of primary infertility presented with regular menses since menarche. FSH following clomiphene ...
Aduloju Olusola Peter OP Department of Obstetrics and Gynaecology, Ekiti State University , Ado-Ekiti , - - 2014
Abstract Background: Twin pregnancy is considered a high risk pregnancy due to associated adverse obstetric outcomes. The objective was to determine the prevalence, complications and the obstetric outcomes of twin deliveries in EKSUTH. Material and methods: A retrospective analysis of twin gestations managed at the Ekiti State University Teaching Hospital, ...
Domingues Ana Patrícia AP Obstetrics Department - Maternidade Dr Daniel de Matos, Coimbra University Hospitals, - - 2014
Abstract Objective: To evaluate the influence of the local of prenatal surveillance of twin pregnancies in the obstetrical results. Methods: A prospective cohort study of multiple pregnancies delivered over a period of 16 years in a tertiary centre was conducted. Were included 861 twin pregnancies. They were compared about obstetric ...
Garretto Diana D Department of Obstetrics, Gynecology and Reproductive Medicine, Stony Brook University, Stony Brook, - - 2014
Early recognition and timely treatment of an interstitial pregnancy is imperative to avoid the high morbidity and mortality of this type of ectopic pregnancy. We report a case of twin interstitial pregnancy that was initially missed on initial sonogram and was subsequently recognized at our institution by transvaginal sonography. The ...
Huber Georgine G Department of Obstetrics and Gynecology, University Regensburg, St. Hedwig Hospital, Regensburg, - - 2014
Abstract Objective. To compare the effectiveness and safety of oral misoprostol versus vaginal dinoprostone for the induction of labor in twin pregnancies. Methods. All twin pregnancies ? 34 weeks 0 days that were induced with either misoprostol or dinoprostone in St. Hedwig Hospital between 2002 and 2013 were included in ...
Nayak Shalini S SS Department of Medical Genetics, Kasturba Medical College, Manipal, Karnataka, - - 2014
We report on two unrelated fetuses born to nonconsanguineous couples with fetal akinesia deformation sequence (FADS). The fetuses shared facial features, micrognathia, fetal finger pads, bulbous digital tips, pterygia, clubfeet, ventriculomegaly, and cerebellar anomalies. Both had loss/absence of Purkinje cells in cerebellum. The first family had a similarly affected previous ...
Osmundson Sarah S SS Departments of Obstetrics and Gynecology, Medicine, and Pathology, Stanford University School of Medicine, Stanford, and the Department of Obstetrics and Gynecology, Santa Clara Valley Medical Center, San Jose, - - 2014
To compare 24-hour urinary protein excretion in twin and singleton pregnancies not complicated by hypertension. We prospectively evaluated mean 24-hour urinary protein excretion in twin and singleton pregnancies between 24 0/7 weeks and 36 0/7 weeks of gestation. Women with urinary tract infections, chronic hypertension, pregestational diabetes, and renal or ...
Vogell Alison A Department of Obstetrics and Gynecology, Jefferson Medical College, and the Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, - - 2014
Bell palsy is a facial nerve neuropathy that is a rare disorder but occurs at higher frequency in pregnancy. Almost 30% of cases are associated with preeclampsia or gestational hypertension. Bilateral Bell palsy occurs in only 0.3%-2.0% of cases of facial paralysis, has a poorer prognosis for recovery, and may ...
Kubotani Juliana Sayuri JS Pelvic Floor Sector, Department of Obstetrics, Federal University of São Paulo, São Paulo, - - 2014
The purpose of this study was to compare the morphologic characteristics of the pelvic floor musculature between women with twin and singleton pregnancies. We conducted a cross-sectional case-control study of 40 nulliparous women aged 20 to 38 years to compare women with singleton pregnancies (n = 23) to women with ...
Stach Sonia Leme SL Department of Obstetrics and Gynecology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, - - 2014
We aimed to examine maternal postpartum complications of twin deliveries according to mode of delivery and investigate the associated risk factors. This was a retrospective cohort review of twin pregnancies with delivery after 26 weeks at a tertiary teaching hospital (1993-2008). The rates of maternal postpartum complications were compared among ...
Himoto Yuki Y Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, - - 2014
To assess the use of magnetic resonance imaging (MRI) for prenatal differentiation between complete hydatidiform mole with a twin live fetus (CHMTF) and placental mesenchymal dysplasia (PMD). Three CHMTF cases and three PMD cases, from two institutions over a 6-year period, were retrospectively included in this study. Clinical findings including ...
Baud David D Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, - - 2014
Both "early" (< 16 weeks' gestation) and "late" (> 26 weeks' gestation) presentations of twin-twin transfusion syndrome (TTTS) are rare and challenging complications of monochorionic/diamniotic twin pregnancies. Growing evidence suggests that fetoscopic laser therapy for both "early" and "late" TTTS is feasible, safe, and yields similar outcomes to cases treated ...
Peeters Suzanne H P SH Department of - - 2014
To evaluate management and outcome of iatrogenic monoamniotic twins (iMAT) compared to twins with intact intertwin dividing membranes after laser surgery for twin-to-twin transfusion syndrome (TTTS). Retrospective analysis of twins treated for TTTS with laser surgery at our center between 2004 and 2012 with and without iatrogenic rupture of the ...
Tendais Iva - - 2014
Abstract Aims: To evaluate the differences in linear and complex heart rate dynamics in twin pairs according to fetal sex combination [male-female (MF), male-male (MM), and female-female (FF)]. Methods: Fourteen twin pairs (6 MF, 3 MM, and 5 FF) were monitored between 31 and 36.4 weeks of gestation. Twenty-six fetal ...
Guillén M A MA Division of Diabetes, Department of Endocrinology and Nutrition, Hospital Universitario La Paz, Madrid, - - 2014
To evaluate the influence of gestational diabetes mellitus on neonatal birthweight, macrosomia and weight discrepancy in twin neonates METHODS: An observational retrospective study was performed. One hundred and six women with gestational diabetes and twin pregnancy and 166 twin controls who delivered viable fetuses > 24 weeks were included. Impact of maternal ...
Zanardini Cristina C Maternal-Fetal Medicine Unit, Department of Obstetrics and Gynaecology, University of Brescia, - - 2014
To assess myocardial performance index (MPI) measured by conventional Doppler and by tissue Doppler imaging (MPI') at 18 weeks' gestation in monochorionic diamniotic twins for the prediction of twin-to-twin transfusion syndrome (TTTS). Single-center observational study from 2009 to 2012. MPI and MPI' were obtained in the left (LV) and right ...
Moon-Grady Anita J AJ Division of Cardiology, Department of Pediatrics and Fetal Treatment Center, University of California San Francisco Benioff Children's Hospital, San Francisco, - - 2014
Twin-twin transfusion syndrome is a complex disease process affecting monochorionic twin pregnancies that has implications for the cardiovascular system in both recipient and donor cotwins. Systolic, diastolic, and structural cardiac changes can occur; these have been the subject of intense study over the past two decades, and the use of ...
Esin S S Department of Obstetrics and Gynecology, Hacettepe University School of Medicine , Ankara , - - 2014
Our objective was to compare the latency periods after preterm premature rupture of membranes (PPROM) and determine its subsequent impact on maternal and fetal outcomes for singleton and twin gestations > 24 weeks' and ≤ 34 weeks' gestation. Delivery in the first 72 h after the rupture of membranes was ...
Kazemier Bm B Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, the - - 2014
Information about the recurrence of spontaneous preterm birth in subsequent twin/singleton pregnancies is scattered. To quantify the risk of recurrence of spontaneous preterm birth in different subtypes of subsequent pregnancies. An electronic literature search in OVID MEDLINE and EMBASE, complemented by PubMed, to find recent studies. Studies comparing the risk ...
Dior Uri P UP Department of Obstetrics and Gynecology, The Hebrew University-Hadassah Medical Center, P.O.B. 12272, Jerusalem 91120, Israel; Braun School of Public Health, The Hebrew University-Hadassah Medical Center, P.O.B. 12272, Jerusalem 91120, Israel. Electronic address: - - 2014
To examine the association of maternal and/or paternal smoking during pregnancy with offspring cardio-metabolic risk (CMR) factors at adolescence and early adulthood, taking into account socio-demographic, medical and lifestyle characteristics of parents and offspring, as well as offspring common genetic variation. We used a population-based cohort of all 17 003 ...
Pickle Sarah S Department of Family Medicine and Community Health, Rutgers Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, Medical Education Building Room 262, New Brunswick, NJ 08901, USA. Electronic address: - - 2014
This article summarizes the literature regarding the epidemiology and prevention of unintended pregnancy in the United States. Because of the Affordable Care Act and its accompanying contraceptive provision, there is a need for more primary care clinicians to provide family planning services. Office-based interventions to incorporate family planning services in ...
Taguchi Takako T Department of Maternal Fetal Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, - - 2014
The aim of this study was to identify the incidence, clinical features, and prenatal risk factors for hypertensive disorders, including gestational hypertension (GH) and pre-eclampsia (PE), in twin pregnancies. We carried out a retrospective cohort study of twin pregnancies managed from the first trimester onward at a single center from ...
Kaveh Mahbod M Department of Pediatrics, Tehran University of Medical Science, Bahrami Hospital, Tehran, - - 2014
Dicephalic parapagus tribrachius conjoined twin is a very rare condition. We present a case of 5-days-old male dicephalic parapagus conjoined twins. The conjoined twins were diagnosed in 4(th) month of pregnancy by ultrasonography. The pregnancy terminates at 36 weeks by cesarean section and triplets were born. The babies were male ...
Knight Ba B NIHR Exeter Clinical Research Facility, University of Exeter, Exeter, UK Royal Devon and Exeter NHS Foundation Trust, Exeter, - - 2014
Recent studies from India have suggested that low vitamin B12 (<150 pmol/l) concentrations in pregnancy are associated with obesity, gestational diabetes, and permanent diabetes 5 years later.(1) These associations may not be present in a Western European Caucasian population, where micronutrient deficiencies are thought to be less common. To assess ...
Breslin E E University Hospitals of Leicester, Leicester, - - 2014
Monochorionic-diamniotic (MCDA) twin pregnancies occur in approximately 1:400 pregnancies and are associated with significant perinatal morbidity and mortality. Whilst there is robust evidence regarding the antenatal management of these pregnancies, the recommended mode of delivery is more controversial with an unquantified risk of acute intrapartum twin-to-twin transfusion syndrome (TTTS). The ...
Darke J J Newcastle University, Newcastle, - - 2014
To compare maternal characteristics and pregnancy outcomes in twin pregnancies to women with and without pre-gestational diabetes. We analysed data on 27 women with pre-gestational diabetes (54 twins) and 6407 women (12,814 twins) without diabetes from the Northern Survey of Twin and Multiple Pregnancy (NorSTAMP) during 1998-2010. Descriptive statistics were ...
Szittya L L Department of Obstetrics and Gynaecology, Cork University Maternity Hospital, Cork, - - 2014
Twin births represent 1.8% of all births in Ireland. These pregnancies are at a greater risk for adverse perinatal outcomes compared to their singleton counterparts. Early diagnosis of amnionicity and chorionicity is essential as monochorionic pregnancies have a 3-5-fold increased risk of fetal morbidity and mortality compared to dichorionic pregnancies. ...
Doherty E E Aberdeen Maternity Hospital, Aberdeen, - - 2014
Chorionicity of twin pregnancies are important to determine for their clinical management. Routine ultrasound examination can determine this, but the accuracy and reliability of ultrasound is uncertain. To determine the accuracy of antenatal ultrasound versus naked eye examination as a predictor of chorionicity of twin pregnancies in our unit. All ...
Chong Dm D Countess of Chester Hospital NHS Foundation Trust, Chester, - - 2014
NICE has introduced a multiple pregnancy national guideline in September 2011 with recommendations for care of these high-risk patients. The management and outcome of twin pregnancies in the Countess of Chester Hospital over a 12-month period were reviewed using NICE guidelines as standards. Retrospective electronic case notes review was undertaken ...
Higgins M M Obstetrics and Gynaecology, University College Dublin, National Maternity Hospital, Dublin, Ireland Maternal Fetal Medicine, Mount Sinai Hospital, Toronto, - - 2014
Chorangiomas (placental haemangiomas) are rarely diagnosed antenatally but have been associated with cardiac failure and poor outcome. The aim of this study was to review cases of antenatally diagnosed placental chorangiomas within in a large tertiary level unit. Retrospective cohort study Between January 2004 and March 2013, over 67,000 infants ...
Hillman Sc S University of Birmingham, Birmingham, - - 2014
Fetoscopic laser coagulation (FLC) has been shown to improve survival and reduce neurological morbidity in twin to twin transfusion syndrome (TTTS). Varying techniques for ablation exist with "Solomonisation" being a selective laser coagulation of placental vessels (SLCPV) with the addition of a subsequent surface coagulation of the placenta between the ...
Kent Em E Perinatal Ireland Research Consortium, Dublin, - - 2014
To evaluate the significance of an abnormal cerebroplacental ratio (CPR) in twin pregnancies. In the prospective multicenter ESPRiT study, twin pregnancies underwent serial sonographic evaluation including multi-vessel Doppler studies. CPR was expressed as the ratio of the pulsatility index (PI) of the middle cerebral artery to the PI of the ...
Siddiqui Anwar Hasan AH Department of Physiology, Jawaharlal Nehru Medical College, Aligarh, - - 2014
Objective: Pregnancy brings about significant changes in respiratory function, as evidenced by alterations in lung volumes and capacities, which are attributable to the mechanical impediment caused by the growing foetus. This study was undertaken in order to identify changes in respiratory function during normal pregnancy and to determine whether such ...
Temple Richard R Naval Hospital Camp Lejune Family Medicine Residency, Camp Lejeune, NC, USA. Email: - - 2014
The death of a fetus late in pregnancy can be devastating. Your role: Help the mother through the physical process, conduct a postdelivery evaluation, and provide support to the grieving family.
Boyer Ananda A Div. of Fetal Imaging, Dept. of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, 3601 W. 13 Mile Rd. Royal Oak, MI, USA 48073. Electronic address: - - 2014
To determine the clinical significance of amniotic fluid sludge in twin pregnancies with a short cervix. We evaluated twin pregnancies with a short cervical length that had an ultrasound between 16 and 26 weeks (n= 78). Pregnancy outcomes in those with sludge (n= 27) and those without (n=51) were compared. ...
Fox Nathan S NS Maternal Fetal Medicine Associates, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: - - 2014
Preeclampsia and IUGR are correlated in singleton pregnancies. The objective of this study was to estimate their relationship in twin pregnancies. Cohort of 578 patients with twin pregnancies delivered by one maternal fetal medicine practice from 2005-2013. Patients with chronic hypertension, monochorionic-monoamniotic placentation, twin-twin transfusion, and major congenital anomalies were ...
Lucovnik Miha M Department of Perinatology, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, - - 2014
Abstract Objective: To examine the impact of pre-pregnancy obesity on adverse outcomes in twin compared to singleton pregnancies. Methods: Dichorionic twin gestations with maternal body mass index >30 were matched to 3 singleton controls. Both obese groups were matched (1:3) with non-obese controls. Rates of preeclampsia, gestational diabetes, cesarean section, ...
Shen Ori O Department of Radiology, Tel Aviv Medical Center, Tel Aviv, - - 2014
Molar tooth sign (MTS) is pathognomonic for Joubert syndrome (JS) and related disorders. We report a case in which MTS was suspected in an 'at risk' patient at 16 weeks' gestation by sonography and at 18 weeks by additional ultrasound. It was then confirmed at 20 weeks by MRI. A ...
Leeners Brigitte B Clinic for Reproductive Endocrinology, University Hospital - - 2014
Abstract Objective: Hypertensive diseases in pregnancy (HDP) occur in 5-8% of all pregnancies and represent one of the most important causes of maternal and fetal morbidity. Even after a normal pregnancy/delivery adaptation to parenthood is a major challenge. However, a successful adjustment is important for future family health. As pregnancy ...
Benoit Richard M RM Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, - - 2014
Clinical Problem Twin-to-twin transfusion syndrome (TTTS) increases perinatal morbidity and mortality for 10 to 15% of monochorionic (MC) gestations. Pathophysiology MC gestations are at risk due to the angioarchitecture of the shared placenta, with anastomoses of varying type, size, and quantity. TTTS results from progression of a chronic perfusion imbalance across unbalanced ...
Baschat Ahmet A AA Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, - - 2014
Twin anemia-polycythemia sequence (TAPS) is a recently described complication of monochorionic placentation characterized by discordance in hemoglobin (Hgb) levels in the absence of amniotic fluid abnormality characteristic of classical twin-twin transfusion syndrome (TTTS). The placental angioarchitecture that predisposes to TAPS consists of small diameter arteriovenous anastomoses and the absence of ...
Bergh Eric E From the Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai - - 2014
Abstract Objective: We sought to estimate the association between CL and fFN and each pathway leading to preterm birth in twin pregnancies. Methods: Cohort study of 560 patients with twin pregnancies who underwent routine serial CL and fFN screening from 22-32 weeks in one maternal fetal medicine practice from 2005-2013. ...
Williams-Wyss Olivia O University of - - 2014
Exposure to poor maternal nutrition around the time of conception results in an early prepartum activation of the fetal pituitary-adrenal axis and in increased adrenal growth and stress response after birth associated with epigenetic changes in a differentially methylated region (DMR) of adrenal IGF2/H19. We have determined the effects of ...
Figueiredo Rita Feguri RF Federal University of Mato Grosso, - - 2014
Orofacial clefts (OFCs) have complex and multifactorial etiologies. Periconceptional folic acid supplementation can significantly reduce the risk of OFC. Evaluate the role of folate and other factors in preventing OFC by analyzing the health and socio-demographic data collected from a population sample. Retrospective case-control study in which mothers with children ...
Okby Rania R Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, POB 151, 84101, Beer Sheva, Israel, - - 2014
To investigate the influence of gestational diabetes mellitus (GDM) on maternal and neonatal outcomes in twin pregnancies. A retrospective population-based study was conducted, comparing maternal and neonatal outcome in women carrying twins with and without GDM. Deliveries occurred in a tertiary medical center between the years 1988 and 2010. Multivariable ...
Springer Stephanie S Medical University of Vienna, Department of Obstetrics and Feto-maternal Medicine, Vienna, - - 2014
To evaluate the prevalence of congenital heart disease (CHD) in monochorionic (MC) twin pregnancies with and without twin-to-twin transfusion syndrome (TTTS) in an unselected cohort, which underwent pre- and postnatal echocardiography. This was a retrospective cohort study including 451 MC twin pregnancies between 2002 and 2012. Complete outcome data were ...
Galjaard Sander S Department of Development and Regeneration, KU Leuven; Department of Obstetrics and Gynecology, University Hospitals Leuven, - - 2014
Monochorionic (MC) twin pregnancies are at increased risk of adverse outcome because of the vascular anastomoses that connect the two fetal circulations. MC monoamniotic (MA) twins are at an even higher risk due to the almost universal cord entanglement and possible compression, which can cause an acute transfusion imbalance between ...
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