Search Results
Results 301 - 350 of 1406
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Genova L - - 2013
Twin anemia-polycythemia sequence (TAPS) is a rare condition which may occur either spontaneously in uncomplicated monochorionic twin pregnancies or may develop after laser treatment in twin-twin transfusion syndrome. TAPS is characterized by a large intertwin discordance in hemoglobin levels without discordance in amniotic fluid levels, and may lead to severe ...
Alves Elisabete - - 2013
Abstract Background: Hypertensive disorders complicating pregnancy increase the risk of adverse obstetric and perinatal outcomes. Aim: To assess the impact of age, education, family history of cardiovascular disease, pre-pregnancy overweight/obesity and weight gain during pregnancy on hypertensive disorders, among primiparae and multiparae. Subjects and methods: In a birth cohort study, ...
Svirsky Ran - - 2013
Abstract Aims: To determine first trimester maternal serum placental protein 13 (PP13) in singletons vs. twins with and without severe preeclampsia (PE). Methods: Serum samples were prospectively collected at 8-14 weeks of gestation. PP13 was determined by solid-phase immunoassay. Patients were recruited in community clinics throughout the country, and from ...
Antsaklis Aris - - 2013
Abstract Aim: To investigate the characteristics of twin pregnancies and their mode of delivery over a 30-year period, in order to define the current trends in clinical practice regarding twin deliveries and the factors that influence these practices. Materials and methods: A retrospective study of twin deliveries at ≥24 weeks ...
Turunen Kaisa - - 2013
Intrahepatic cholestasis of pregnancy has been shown to have a genetic predisposition. We studied whether Finnish women who had suffered from the disorder reported their first degree relatives to have had liver dysfunction during their pregnancies. Questionnaires were sent in autumn 2010 to a total of 544 former intrahepatic cholestasis ...
Okby Rania - - 2013
Abstract OBJECTIVE: The aim of this study was to investigate whether induction of labor in twin pregnancies is associated with higher rates of maternal complications as compared to singletons. METHODS: A retrospective population-based study was conducted to compare maternal complications following induction of labor in twin pregnancies and singletons at ...
Ashoor Ghalia - - 2013
Background: Thyroid disease during pregnancy may be associated with increased risk of various pregnancy complications. It is known that serum thyroid stimulating hormone (TSH) is suppressed by human chorionic gonadotrophin (hCG) in early pregnancy, and that higher hCG levels in twin pregnancies may cause a more pronounced physiologic suppression, this ...
Davanzo Julie - - 2013
We investigate factors affecting women's decisions to terminate pregnancies in Matlab, Bangladesh, using logistic regression on high-quality data from the Demographic Surveillance System on more than 215,000 pregnancies that occurred between 1978 and 2008. Variables associated with the desire not to have another birth soon (very young and older maternal ...
Pagani Giorgio - - 2013
OBJECTIVES: The aims of this study were to ascertain the outcome of twin reversed arterial perfusion (TRAP) sequence cases managed in our unit and to systematically review the cases reported in the literature treated using intrafetal laser therapy. METHODS: This was a retrospective cohort study of all TRAP sequence cases ...
Hjortø Sofie - - 2013
Abstract Objectives: To investigate the effect of chorionicity and twin-to-twin delivery time interval on short-term outcome in the second twin. Additionally, to investigate predictors of adverse outcome in both twins. Methods: Data included vaginally delivered twins (≥ 36 weeks) from Copenhagen University Hospitals (2001-09). The association between delivery interval and ...
Segal Nancy L - - 2013
The twin children who survived the Holocaust and the horrific medical experiments conducted by Nazi doctors are sometimes overlooked in the relevant literature. This topic and more were discussed as part of an annual conference hosted by students from Yeshiva University's Medical Ethics Society in October 2012. A selective summary ...
Byers Benjamin D - - 2013
To evaluate the perinatal outcomes in twin pregnancies discordant for single umbilical artery (SUA). This was a retrospective cohort study. Our database was searched for all cases of twin gestation and SUA from 1997-2009. We reviewed all the maternal and neonatal records and placental pathology reports. The outcomes of the ...
Al Riyami Nihal - - 2013
The aim of this study is to compare the neonatal outcomes of monochorionic and dichorionic twin pregnancies. A retrospective cohort study involving 51 twin pregnancies followed and delivered at Sultan Qaboos University Hospital was conducted between January 2006 and December 2011. Thirty six (71%) pregnancies were dichorionic diamniotic (DCDA), 14 ...
Dragović Milan - - 2013
Lateralization of brain functions such as language and manual dominance (hand preferences and fine motor control) are most likely under genetic control. However, this does not preclude the effect of various environmental factors on functional brain lateralization. A strong association of non-right-handedness (left- and mixed-handedness) with various neurodevelopmental conditions (e.g. ...
Zhao D P - - 2013
INTRODUCTION: Most monochorionic (MC) twin pregnancies have an uncomplicated course, but some develop severe complications including selective intrauterine growth restriction (sIUGR), twintwin transfusion syndrome (TTTS) and twin anemia-polycythemia sequence (TAPS). The underlying pathogenesis of these various complications is associated with the ubiquitous presence of vascular anastomoses in MC placentas. METHODS: ...
Flöck A - - 2013
OBJECTIVE: Nuchal translucency (NT) measurement in assisted reproduction treatment (ART) twins is less extensively investigated. Therefore, the present study compared NT measurements of spontaneously conceived twins with ART twins in dichorionic (DC) and monochorionic (MC) pregnancies. METHODS: Retrospective analysis of 706 unaffected twins between 11 + 0 and 13 + 6 weeks conceived either ...
Yogev Yariv - - 2013
Abstract OBJECTIVE: To compare the performance of the 50g-glucose challenge test (GCT) and the 100g-oral glucose tolerance test (OGTT) in twin versus singleton pregnancies. METHODS: A retrospective study of all women who underwent a GCT (24 to 28 weeks) and delivered in a single tertiary medical center (2001-2012). The performance ...
De Paepe Monique E - - 2013
Abstract Approximately 20% of all twin pregnancies are monochorionic. Between 9% and 15% of all monochorionic twin gestations are complicated by severe chronic twin-to-twin transfusion syndrome (TTTS), characterized by a gradual shift of blood volume from the donor twin to the recipient twin through placental vascular connections 1-3. The prognosis ...
Ruano Rodrigo - - 2013
OBJECTIVE: To document perinatal outcomes following the "Solomon technique" in the selective photocoagulation of placental anastomoses for severe twin-twin transfusion syndrome (TTTS). METHODS: Between January 2010 and July 2012, data were collected from 102 consecutive monochorionic twin pregnancies complicated by severe TTTS that underwent fetoscopic laser ablation. We compared outcomes ...
Biederman Joseph - - 2013
Objective. Preclinical studies link prenatal nicotine exposure with the development of both ADHD-like phenotype in rodents and blockade of extinction learning in a fear conditioning paradigm, a preclinical model of posttraumatic stress disorder (PTSD). While these findings suggest that either ADHD, prenatal nicotine exposure, or both could be a risk ...
Kutuk Mehmet S - - 2013
Backround: The schisis theory suggests that neural tube defect (NTD), cleft lip and palate (CL/P), omphalocele and diaphragmatic hernia are associated to each other more frequently than at the expected random combination rates in a given fetus. However, it is unusual to see schisis-associated defects concordantly in dichorionic twin pregnancy ...
Yamamoto Ryo - - 2013
Introduction: The appropriate effectiveness of inter-twin amniotic fluid discordance (AFD) in the early second trimester for the prediction of severe twin-twin transfusion syndrome (TTTS) was evaluated. Materials and Methods: The largest AFD between 16 and 18 weeks' gestation was analyzed in correlation with TTTS development defined by polyhydramnios with a ...
Leung Tak Y - - 2013
OBJECTIVE: To provide an individualized assessment of fetal trisomy 21 and trisomy 18 status for twin pregnancies by maternal plasma DNA sequencing. METHOD: Massively parallel sequencing was performed on the plasma/serum DNA libraries of eight twin pregnancies and 11 singleton pregnancies. The apparent fractional fetal DNA concentrations between genomic regions ...
Mulder Eduard J H - - 2013
OBJECTIVE: Maternal administration of 17-alpha-hydroxyprogesterone caproate (17OHPC) is increasingly utilized to prevent preterm birth, but fetal safety of 17OHPC is still a matter of concern. This study aimed to assess whether exposure to 17OHPC during the second and third trimesters of pregnancy affects fetal biometry in twin gestations. METHODS: We ...
Fox Nathan S - - 2013
Objective Twin pregnancy is associated with an increased incidence of preeclampsia. However, it is unknown if the risk factors for preeclampsia in twin pregnancies are the same as those in singleton pregnancies.Methods Case-control analysis of all twin pregnancies managed by one maternal-fetal medicine practice from 2005 to 2012. Patients with ...
Nathan S Fox - - 2013
Abstract Objective: To describe pregnancy characteristics associated with the occurrence of spontaneous version in twin pregnancies from 20 weeks until delivery. Study Design: Review of ultrasound and pregnancy data for all twin pregnancies delivered >24 weeks by one Maternal-Fetal Medicine practice from June 2005 - May 2012. For each 4-week ...
Hugon-Rodin Justine - - 2013
Abstract Cord accidents are the principal cause of the high rates of morbidity and mortality associated with monoamniotic twins. Observation of an umbilical artery notch might be a highly specific sign for cord entanglement involving a tight cord knot. It thus justifies the implementation of intense surveillance and should be ...
Argoti Pedro S - - 2013
INTRODUCTION: Single fetal demise in monochorionic twin gestations represents a significant risk for co-twin demise and neurodevelopmental morbidity. Indirect observations have led to a theory of acute exsanguination of the normal twin into the dying twin as the proposed mechanism. CASE: A 22-year-old G3P2 (2002) female with Quintero Stage IV ...
Lee Hanmin - - 2013
Objective: To report the North American Fetal Therapy Network (NAFTNet) Registry data on the outcomes of using radiofrequency ablation to treat twin-reversed arterial perfusion (TRAP). Methods: This was a retrospective review of the records of all patients who underwent percutaneous radiofrequency ablation of an acardiac twin after referral to 12 ...
Davidoff Dahlia F - - 2013
Twin-twin transfusion syndrome (TTTS) is an antenatal complication of monochorionic multiple gestations. There have been few studies exploring the role of laser photocoagulation or outcomes following treatment in monochorionic triplet pregnancies with TTTS. We present a case where TTTS and twin anemia-polycythemia sequence (TAPS) complicated a monochorionic triplet pregnancy. Following ...
York Timothy P TP Department of Human and Molecular Genetics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA. - - 2013
Although there is increasing evidence that genetic factors influence gestational age, it is unclear to what extent this is due to fetal and/or maternal genes. In this study, we apply a novel analytical model to estimate genetic and environmental contributions to pregnancy history records obtained from 165,952 Swedish families consisting ...
Asnafi Nesa - - 2013
Abstract Objective: In singleton pregnancy, short cervix is associated with the risk of spontaneous preterm delivery (SPD). On the otherhand, twin pregnancy increases rate of preterm delivery, so this study was designed to evaluate the transvaginal sonographic (TVS) measurement of cervical length (CL) to predict preterm birth in twin pregnancy.Methods: ...
Lopes Lilian M - - 2013
BACKGROUND: The aim of this study was to determine the accuracy of prenatal echocardiography in the diagnosis of intracardiac malformations and the degree of cardiac fusion in conjoined twins presenting to a single center over a 25-year period. METHODS: The study group included 53 sets of conjoined twins from 1987 ...
Lenis Cordoba Natalia - - 2013
Abstract Aim To compare the rate of pregnancy loss between twin pregnancies undergoing a genetic amniocentesis (AC) and a control group with similar characteristics. Methods Prospective observational study on a population of twin pregnancies referred to our prenatal diagnosis unit for screening from 1990 to 2010. Those women referred for ...
Larner A J - - 2013
A patient with delusion of pregnancy as an early feature of frontotemporal dementia with motor neurone disease (FTD/MND) who was reported some years ago was posthumously found to harbor the C9ORF72 hexanucleotide repeat expansion, now known to be the most common genetic cause of FTD/MND. Some series have found psychosis ...
Kawata Mitsuhiro - - 2013
Fetuses positioned next to littermates of the opposite sex may develop different sexually related traits and aggressive behaviour in later life. These effects of intrauterine position are due to hormonal transfer between fetuses. Testosterone from a male fetus that crosses the fetal membrane of an adjacent female fetus can affect ...
Nobili Elena - - 2013
To investigate the indications for offering selective fetal reduction in monochorionic (MC) and dichorionic (DC) twins and to correlate obstetric outcome with the antenatal procedure. All cases of MC and DC twins discordant for structural anomalies and for chromosomal/genetic abnormalities were included. Selective reductions performed for twin-to-twin transfusion syndrome or ...
Harper Lorie M - - 2013
Objectives We aimed to determine the accuracy of sonographic formulas for estimating birth weight in twin pregnancies. Methods We conducted a retrospective cohort study of consecutive twin pregnancies undergoing sonography at within 1 week of delivery. Pregnancies were included if biometric measurements and birth weight were available and excluded if ...
Teoh Mark - - 2013
To evaluate the performance of a collaborative fetal therapy service for treatment for twin-twin transfusion syndrome (TTTS). The Victorian Fetal Therapy Service (VFTS) was developed in 2006. It is a state-based three-centre collaborative service comprising a surgical team and clinical leadership group, designed to optimise access to, and performance of, ...
Jacob Francois D - - 2013
Trisomy 21 is the most common viable trisomy. Although it is invariably associated with mild to severe developmental delay and intellectual disability, no gross central nervous system malformation has been consistently identified in individuals with trisomy 21. We present the case of a monozygotic twin pregnancy in which both fetuses ...
Mouawia Hussein H Department of Biology, Faculty of Science, Lebanese University, Beirut, Lebanon ; Paris Descartes University, Paris, - - 2013
Detection of Circulating Fetal Trophoblastic Cells (CFTC) by single cell genotyping not only allows to identify fetal cells from maternal blood, but also to characterize their bi-parental genome. We have tested intact fetal trophoblastes recovered at 4th to 10th weeks of gestation (WG) from blood (10 ml per mother) of ...
Werder Emily E Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20852, - - 2013
To evaluate the effect of maternal chronic disease on obstetric complications among twin pregnancies. Multicenter, retrospective, observational study. Clinical centers (19 hospitals). Twin pregnancies (n = 4,821) delivered ≥ 23 weeks of gestation and classified by maternal chronic disease (either none or any of the following: asthma, depression, hypertension, diabetes, ...
Brady Paula C - - 2013
OBJECTIVE: To describe the early β-hCG trends in vanishing twins compared with normally progressing singleton and twin pregnancies. DESIGN: Retrospective cohort study. SETTING: University-based infertility clinic. PATIENT(S): Women undergoing fresh IVF/intracytoplasmic sperm injection (ICSI) cycles between 1998 and 2010. INTERVENTION(S): Early β-hCG level increase in vanished twin pregnancies was compared with ...
Trojner-Bregar Andreja - - 2013
OBJECTIVE: To evaluate the puerperal complications following twin deliveries. STUDY DESIGN: We conducted a population-based analysis of puerperal delivery-related complications of twins born in Slovenia for comparing three groups of births (vaginal, elective and emergent cesarean). RESULTS: A total of 1,001 elective, 1,109 emergent cesarean sections, and 2,204 vaginal twin ...
Haas Dorothea - - 2013
Smith-Lemli-Opitz (SLOS), or RSH syndrome, is an autosomal recessive deficiency of 7-dehydrocholesterol reductase (DHCR7) resulting in an accumulation of 7- and 8-dehydrocholesterol (7- and 8-DHC) in tissues and body fluids. At birth patients have variable malformations of CNS, heart, kidney, genitalia, and limbs, which may be life-limiting. In later course, ...
Zanardo Vincenzo - - 2013
Background and objective: Intrauterine growth restriction (IUGR) may be associated with significantly higher aortic intima-media thickening (aIMT) values. It is unknown if fetal aIMT is associated with glomerulosclerosis and amniotic albuminuria in utero. Design, setting, participants, and measurements: Fetal abdominal aIMT and amniotic albumin/creatinine ratio (ACR) were measured in 126 ...
Sparks Teresa N TN Department of Obstetrics & Gynecology, Brigham and Women's Hospital/Massachusetts General Hospital , Boston, MA 02115, USA. - - 2013
Examine whether dichorionic (DC) and monochorionic (MC) twins exhibit different rates and severity of preeclampsia. Retrospective cohort study of 695 twin pregnancies from 2002 to 2007. DC pregnancies were compared to MC pregnancies, with the primary outcome of interest being development of preeclampsia, and the secondary outcome being severity of ...
Khalil Mohamed Ibrahim - - 2013
OBJECTIVE: To assess the association between cervical length (CL) and change of CL over two measurements and preterm birth (PTB) at <32 weeks in asymptomatic twin pregnancies. STUDY DESIGN: This study was undertaken in the multiple pregnancy antenatal clinic at the Security Forces Hospital (SFH), a tertiary care hospital in ...
Murata Masaharu - - 2013
AIM: To clarify perinatal outcomes of monoamniotic (MM) twin pregnancies. MATERIAL AND METHODS: MM twins delivered in seven tertiary perinatal centers during the last decade were retrospectively evaluated. All pregnant women were scheduled to begin inpatient management at around 24 weeks of gestation and undergo a planned cesarean section beyond ...
Nir Amiram - - 2013
Singleton pregnancy in patients with single ventricle after the Fontan operation has been reported with significant offspring and maternal complications. We report a twin pregnancy and premature delivery, in a patient following the Fontan operation.
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