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St Clair John J Pieta Research, Edinburgh, - - 2014
Monozygotic (MZ) twinning is generally considered to be rare in species other than human. We inspected sex ratios in European zoo-bred ring-tailed lemurs (Lemur catta), revealing a significant excess of same-sex twins. Of 94 pairs, 60 (64%) were either both males or both females (p = .004). Application of the ...
Allaf M Baraa MB Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine, Pavilion for Women-Texas Children's Fetal Center, 6651 Main St, Suite F1020, Houston, TX 77030 USA. - - 2014
Objectives- The purpose of this study was to investigate whether discordant nuchal translucency and crown-rump length measurements in monochorionic diamniotic twins are predictive of adverse obstetric and neonatal outcomes. Methods- We conducted a multicenter retrospective cohort study including all monochorionic diamniotic twin pregnancies with two live fetuses at the 11-week ...
Zuberi Zia Z Department of Cardiology, King College Hospital, Denmark Hill, - - 2014
We describe a patient presenting with incessant ectopic atrial tachycardia during a high risk twin pregnancy. Tachycardia was resistant to escalating doses of beta-blockade with digoxin. Because of increasing left ventricular dysfunction early in the third trimester, catheter ablation was performed successfully at 30 weeks gestation. Electro-anatomic mapping permitted the ...
Nguyen Ngoc Minh Phuong NM Department of Human Genetics, McGill University Health Centre Research Institute, Montreal, Quebec Canada ; Department of Obstetrics and Gynecology, McGill University Health Centre Research Institute, Montreal, Quebec - - 2014
Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma, ...
Felekis Theodoros T 0000-0002-7059-476X Department of Obstetrics and Gynecology, "G. Hatzikosta" General State Hospital, Makrygianni Avenue, 45445 Ioannina, - - 2014
Heterotopic triplet pregnancy is an exceptionally rare medical condition. The broad use of assisted reproductive technologies has contributed to the increase of ectopic and subsequently heterotopic pregnancy rate, masking a life-threatening condition for the gravid and the intrauterine pregnancy. We describe a case of a woman with heterotopic triplets at ...
Kyvernitakis Ioannis I Department of Prenatal and Perinatal Medicine, Clara Angela Foundation, Koenigsallee 36, 14193 Berlin, Germany ; Department of Pre- and Perinatal Medicine, Center of Mother and Child, University Hospital of Giessen and Marburg, Philipps University of Marburg, Campus Marburg, Baldinger Straße 1, 35043 Marburg, - - 2014
Radical and repeated cone biopsies are associated with a high risk of spontaneous preterm birth. A 30-year-old gravida 1 presented with a spontaneous dichorionic twin pregnancy. She had a history of two radical surgical conizations. By speculum examination, no cervical tissue was detected. A history-indicated transabdominal cervicoisthmic cerclage was performed ...
R Kalyani K Associate Professor, Department of Pathology, ESIC Medical College & PGIMSR , Bangalore, Karnataka, India - - 2014
Twin reversed arterial perfusion (TRAP) syndrome is a rare condition (0.3:10,000 births) that occurs in monochorionic twin pregnancies, resulting in coexistence of a normal "pump" twin and an acardiac twin. The acardiac twin is dependent upon the normal twin to provide circulation by means of vascular anastomosis. Many of the ...
Akhanoba Folasade F Department of Obstetrics and Gynaecology, Addenbrooke's Hospital, Cambridge, - - 2014
A 41-year-old nulliparous woman, with a medical history of unexplained infertility and multiple in vitro fertilisation (IVF) cycles with immunosuppressive therapy, was admitted to our tertiary obstetrics unit with sepsis at 18 weeks of pregnancy with dichorionic diamniotic twins. Candida glabrata was grown from her blood cultures, then subsequently from ...
Nigam Aruna A Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, New Delhi, - - 2014
Acardiac twin is a rare congenital anomaly and is exclusively associated with monochorionic twin pregnancies. The abnormalities occur due to abnormal communication between the two fetuses in the form of arterioarterial and venovenous communications, resulting in a grossly abnormal acardiac twin with reduction anomalies mainly of the upper body and ...
Gan Lu - - 2014
Studies of twin pairs discordant for autoimmune conditions provide a unique opportunity to explore contributing factors triggered by complex gene-environment interactions. In this cross-sectional study, thirty-one monozygotic or dizygotic twin pairs discordant for myositis or systemic lupus erythematosus (SLE), along with matched healthy controls were evaluated for antibodies against a ...
Luo Qi-Guang QG Department of Obstetrics and Gynecology, Sainte-Justine Hospital, University of Montreal, Montreal, Canada; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, - - 2014
Pregnancy-induced or gestational hypertension is a common pregnancy complication. Paradoxically, gestational hypertension has been associated with a protective effect against perinatal mortality in twin pregnancies in analytic models (logistic regression) without accounting for survival time. Whether this effect is real remains uncertain. This study aimed to validate the impact of ...
Boukhanni Lahcen L 0000-0002-2006-9465 Department of Obstetrics and Gynecology, University Hospital of Marrakesh, Cadi Ayyad University, 40 000 Marrakesh, Morocco ; Department of Obstetrics & Gynecology, Mother and Child Hospital, Mohammed VI University Hospital, Cadi Ayyad University, School of Medicine, 40 000 Marrakesh, - - 2014
Intramyometrial pregnancy is a rare form of ectopic pregnancy. It makes a diagnostic and therapeutic challenge. If misdiagnosed the intramyometrial pregnancy can cause a uterine rupture and become life-threatening condition. We report a case of intramyometrial pregnancy in twin pregnancy following IVF with spontaneous abortion of the first twin At ...
De la Calle M - - 2014
Prevalence ofanencephaly in dichorionic twins is higher than in singleton pregnancies. The authors report two cases with two different management strategies. Spontaneous dichorionic diamniotic twin pregnancy with the second twin diagnosed with anencephaly at 12 weeks gestation. Selective feticide was performed at the age of 13.2 weeks. Vaginal delivery occurred ...
Cakiroglu Yigit Y Department of Obstetrics and Gynecology, Kocaeli University School of Medicine, Umuttepe Kampusu, Kocaeli, - - 2014
Pentalogy of Cantrell is a rare malformation described in the literature. We report a case of pentalogy of Cantrell associated with left limb deficiency in a twin pregnancy. The fetus with multiple anomalies revealed kyphosis, ectopia cordis, and a large defect with protruding liver and bowel loops at 12 weeks ...
Miyazaki Masahide M Department of Obstetrics and Gynecology, Tagawa Municipal Hospital, Fukuoka, - - 2014
We report a case of reversal of twin-to-twin transfusion syndrome (Stage IV TTTS) at 24 weeks of gestation after fetoscopic laser photocoagulation (FLP) for communicating vessels. The pathology of reversal of TTTS found that the 'initial' donor developed polyhydramnios whereas the 'initial' recipient developed oligohydramnios. With careful follow-up, the hydrops ...
Rutherford Julienne N JN Department of Women, Children, and Family Health, College of Nursing, University of Illinois at Chicago, Chicago, Illinois, United States of America; Department of Anthropology, University of Illinois at Chicago, Chicago, Illinois, United States of - - 2014
The impact of the intrauterine environment on the developmental programming of adult female reproductive success is still poorly understood and potentially underestimated. Litter size variation in a nonhuman primate, the common marmoset monkey (Callithrix jacchus), allows us to model the effects of varying intrauterine environments (e.g. nutrient restriction, exposure to ...
Papoutsis D - - 2014
This is the second case in literature of posterior reversible encephalopathy syndrome (PRES) in a twin pregnancy complicated by preeclampsia-eclampsia. A 27-year-old primigravida with dichorionic diamniotic twin pregnancy was admitted at 36 weeks of gestation for induction of labour due to preeclampsia. On the second day postpartum, the patient developed ...
Mehata Suresh S 0000-0003-3426-2108 Nepal Health Sector Support Programme, Ministry of Health and Population, Ramshah Path, Kathmandu 44600, - - 2014
Contraceptive use during the postpartum period is critical for maternal and child health. However, little is known about the use of family planning and the determinants in Nepal during this period. This study explored pregnancy spacing, unmet need, family planning use, and fertility behaviour among postpartum women in Nepal using ...
Kubotani Juliana Sayuri JS Pelvic Floor Sector, Department of Obstetrics, Federal University of São Paulo (UNIFESP), Rua Carlos Weber, 956 Apartment 113 Visage, Vila Leopoldina, 05303-000 São Paulo, SP, - - 2014
The aims of this study were to compare perineal distensibility between women with twin and singleton pregnancies and to correlate these women's perineal distensibility with anthropometric data. This prospective cross-sectional case-control study was conducted among nulliparous women, of whom 20 were pregnant with twins and 23 with a single fetus. ...
Aggarwal Ieera I Department of Gynaecological Oncology, KK Women's and Children Hospital, Singapore, - - 2014
Spontaneous haemoperitoneum in pregnancy (SHiP) is a rare but serious condition associated with an adverse pregnancy outcome. We present a case of previable twin pregnancy presenting with SHiP secondary to endometriosis, necessitating an emergency laparotomy and hysterotomy as a life-saving measure to achieve haemostasis. At laparotomy there was massive haemoperitoneum ...
Tokmak Aytekin A 0000-0001-5739-5689 Department of Obstetrics and Gynecology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, 06240 Ankara, - - 2014
The aim of this study is to discuss a rare association of iniencephaly and holoprosencephaly and to state the importance of pregnancy termination in early gestational weeks. An 18-year-old nullipara was admitted to our perinatology service with a diagnosis of neural tube defect. Based on the ultrasonographic findings of alobar ...
Egic Amira S AS High-Risk Pregnancy Department, Obstetric and Gynecology Clinic "Narodni Front", University of Belgrade, Street Kraljice Natalije 62, 11000 Belgrade, - - 2014
Objective. Our objective was to estimate degree and rate of discordant growth and its impact on perinatal outcome in dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared to those conceived spontaneously. Study Design. Growth discordance was defined as 90th percentiles for the study population. Adverse perinatal outcome was ...
Kurdoglu Zehra Z Department of Obstetrics and Gynecology, Faculty of Medicine, Yuzuncu Yil University, 65080 Van, Turkey ; Yuzuncu Yil Universitesi Tip Fakultesi, Kadin Hastaliklari ve Dogum Anabilim Dali, Dursun Odabas Tip Merkezi, Kampus, 65080 Van, - - 2014
Brain tumors are rarely diagnosed during pregnancy. Accelerated growth of intracranial meningiomas during pregnancy sometimes requires urgent surgical intervention. We describe a 41-year-old pregnant woman with severe neurological decompensation requiring immediate neurosurgery. Cesarean section resulted in maternal death. Meningioma diagnosed during a viable pregnancy should be managed according to the ...
Ruano Rodrigo R Department of Obstetrics and Gynecology, Faculdade de Medicinda da Universidade de São Paulo, São Paulo, - - 2013
to report a case of fetal urethral stenosis diagnosed and treated by fetal cystoscopy. We report a fetus with severe megabladder, 'keyhole' sign that underwent fetal cystoscopy at 22 weeks. There was a familial history of mild urethral atresia. Fetal cystoscopy revealed a congenital urethral atresia. A guidewire was advanced ...
Gee Rebekah E RE Louisiana State University Department of Obstetrics and Gynecology and School of Public Health, New Orleans, LA 70130. Electronic address: - - 2013
To determine the contribution of monozygotic twining to IVF multiple births STUDY DESIGN: We performed a retrospective analysis of the incidence of monozygotic twining in multiple births resulting from fresh embryo transfers using 2006-2010 data from the Society for Reproductive Technology Clinic Outcome Reporting System (SART CORS). The number of ...
Weisz B B Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel; Sackler school of medicine, Tel-Aviv University, Tel-Aviv; Talpiot medical leadership program, Sheba Medical - - 2013
Monochorionic twins, treated by laser due to twin-twin-transfusion syndrome (TTTS) are at increased risk of neurodevelopment impairment. Our aim was to evaluate the additional value of Diffusion Weighted Imaging (DWI) over fetal sonography and T2-MRI in detection of acute ischemic cerebral lesions shortly following fetoscopic laser coagulation (FLC). This is ...
Huang Xuan X Fetal Medicine Center, Department of Obstetrics and Gynecology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, - - 2013
To assess the performance of non-invasive prenatal testing for trisomy 21 and 18 based on massively parallel sequencing of cell-free DNA from maternal plasma in twin pregnancies. A double-blind study was performed over 12 months. A total of 189 pregnant women carrying twins were recruited from seven hospitals. Maternal plasma DNA ...
Inklaar M J MJ Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The - - 2013
To estimate incidence and risk factors of severe cerebral injury in survivors from monochorionic pregnancies with selective intrauterine growth restriction (sIUGR) and/or birth weight discordance (BWD). Electronic databases were searched for studies describing perinatal and neurologic outcome in monochorionic twins with sIUGR and/or BWD. Exclusion criteria were twin-twin transfusion syndrome, ...
Chaveeva Petya P Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, - - 2013
Objective: To describe a new technique for embryo reduction (ER) in dichorionic triplet (DCT) pregnancies. Methods: In 22 DCT pregnancies, ER to dichorionic twins was carried out at 11.3-13.9 weeks' gestation by ultrasound-guided laser ablation of the pelvic vessels of one of the monochorionic twins. Results: Intrafetal laser was successfully ...
Caserta D D Department of Gynaecologic-Obstetrical Sciences and Urological Sciences, University of Rome Sapienza, S. Andrea Hospital, Rome, Italy. Electronic address: - - 2013
To compare maternal and perinatal outcomes in twin pregnancies conceived via assisted reproductive techniques (ART) compared with spontaneous twin pregnancies. This retrospective study examined 345 dichorionic, di-amniotic twin pregnancies (207 conceived spontaneously and 138 conceived via ART), delivered between January 2007 and June 2011 at the San Pietro Fatebenefratelli Hospital, ...
Mocarzel Carolina Carvalho CC Grupo Perinatal, Rio de Janeiro, - - 2013
Objective: The aim of this study was to assess fetal urinary production rates (FUPR) in twin gestations using 3D ultrasonography with VOCAL® (virtual organ computer-aided analysis) and to develop a curve of normal values for the target population. Methods: A cross-sectional study was performed in 30 normal twin pregnancies with ...
Morikawa Mamoru - - 2013
Abstract Aim: It is unknown whether weekly maternal weight gain differs between Japanese women with singleton, twin, and triplet pregnancies. Methods: Gestational weight gain defined as net weight gain during pregnancy was analyzed in 135,036 pregnant Japanese women, including 128,838 with singletons, 5573 with twins, and 132 with triplets, who ...
Maymon R R Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel, affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, - - 2013
The impact of nuchal translucency (NT) screening in assisted reproduction technology (ART) twins is still not properly addressed in the literature. The current study aim was to assess the NT thickness in twins following various modes ART's, to compare this with spontaneous twins conception and to differentiate results with regard ...
Soundararajan Lakshmi Priya LP Wessex Maternal Fetal medicine Unit, University hospitals Southampton NHS foundation trust, Southampton, United - - 2013
Starry sky appearance is a sonographic pattern described in diffuse liver pathology, characterized by clearly identified portal venules (stars) and diminished parenchymal echogenicity (sky) that accentuates the portal venule walls(1) . Starry sky pattern has been reported previously in a single case report in association with twin twin transfusion syndrome ...
Lewi Liesbeth L Fetal Medicine Unit, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address: - - 2013
Poor growth is a common problem in twin pregnancies, and management poses some unique challenges as the wellbeing of both twins have to be taken into account at all times. The decision to deliver the twins to prevent an intrauterine demise of the growth-restricted twin will, therefore, depends on the ...
Oohashi Masanao - - 2013
To assess the outcome of monochorionic diamniotic (MD) twins with the aid of the MD-twin score. We enrolled 112 MD-twin women in a tertiary perinatal center from 1997 to 2009. The MD-twin score was prospectively applied once per week to women who did not have twin-to-twin transfusion syndrome (TTTS) after ...
Berretta Roberto - - 2013
Interstitial pregnancy is considered one of the most hazardous types of ectopic pregnancies, with a mortality rate of 2-2.5%. We describe a case of a viable monochorionic twin pregnancy in a 35-year-old woman successfully treated with systemic methotrexate associated with bilateral uterine arteries' embolization. β-hCG was undetectable 67 days after ...
Diehl Werner W University Medical Centre Hamburg-Eppendorf, Department of Obstetrics and Foetal Medicine, Martinistraße 52, 20246 Hamburg, Germany. Electronic address: - - 2013
Twin-twin transfusion syndrome complicates up to 15% of monochorionic pregnancies in the mid-trimester, and results in high perinatal mortality and morbidity if left untreated. Although some humoral factors play a role in the pathogenesis of the disease, an unequal placental sharing and the presence of placental vascular anastomoses at the ...
Huang Xuekun - - 2013
Pregnancy in Sheehan's syndrome (SS) is extremely rare. We present the first reported case of twin pregnancy with complete hydatiform mole (CHM) and a coexistent fetus (CHCF) in a patient with SS. A 29-year-old Chinese patient with SS became pregnant following one cycle of ovulation induction with human menopausal gonadotropin ...
Struble Craig A CA Ariosa Diagnostics, Inc., San Jose, Calif., - - 2013
Objective: To estimate fetal fraction (FF) in monozygotic and dizygotic twin pregnancies. Methods: Maternal plasma samples were obtained from 35 monochorionic twin pregnancies with male fetuses (monozygotic) and 35 dichorionic pregnancies discordant for fetal sex (dizygotic) at 11-13 weeks' gestation. Cell-free DNA was extracted and chromosome-selective sequencing with digital analysis ...
Makrydimas George G Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Stavros Niarchos Avenue, 45500 Ioannina, Greece. Electronic address: - - 2013
About 13% of twins are born before 34 weeks and 7% before 32 weeks. The prediction of preterm birth in twins is based on the same tests as in singleton pregnancies. In twin pregnancies, the cut-off for short cervix at the second trimester scan is less than 25 mm (compared with ...
D'Antonio F - - 2013
The aim of this study was to determine the association between biometry discordance at the time of the anomaly scan and adverse perinatal outcomes in twin pregnancies. Retrospective cohort study. Nine hospitals in the Southwest Thames Region of London Obstetric Research Collaborative (STORK). Population multicentre retrospective study of all twin ...
Wang Xike X Children's Heart Center, Xinhua Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200092, P.R. - - 2013
The present study aimed to investigate genetic and environmental factors involved in the pathogenesis of congenital heart disease (CHD). A total of 61 familial pedigrees with CHD were analyzed, and 134 patients out of 761 family members had a diagnosis of CHD confirmed. The present study revealed that the prevalence of ...
Miller Elizabeth E Division of Adolescent Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15213, USA. Electronic address: - - 2013
Reproductive coercion (RC) - birth control sabotage and coercion by male partners to become pregnant and to control the outcome of a pregnancy - has been associated with a history of both intimate partner physical and sexual violence (IPV) and unintended pregnancy among females utilizing reproductive health services. The temporal ...
D'Antonio Francesco F Fetal Medicine Unit, Division of Developmental Sciences, St George's University of London, London SW17 0RE, - - 2013
Early ultrasound assessment and accurate determination of chorionicity is crucial so that appropriate care of multiple pregnancy can be provided. It is best achieved in the first trimester of pregnancy using the Lambda 'λ' and 'T' signs. Accurate labelling of the twins is needed to ensure that the same individual ...
Alptekin Hüsnü - - 2013
The extended use of assisted reproductive technologies is increasing the heterotopic pregnancies, leading to a potentially dangerous condition for the intrauterine pregnancy and the mother. We report a case of unruptured heterotopic pregnancy following IVF-ET at 6 weeks of gestation and the patient was treated with salpingostomy under spinal anesthesia. ...
Rode Line L Center of Fetal Medicine, Department of Obstetrics, Copenhagen University Hospital, 2100 Rigshospitalet, - - 2013
The incidence of twin gestation has increased markedly over the past decades, mostly because of increased use of assisted reproductive technologies. Twin pregnancies are at increased risk of preterm delivery (i.e. birth before 37 weeks of gestation). Multiple gestations therefore account for 2-3% of all pregnancies but constitute at least ...
Dias Tiran T Department of Obstetrics and Gynecology, District General Hospital, Ampara, Sri Lanka. Electronic address: - - 2013
Timing of delivery of twins should be decided when the benefit of prolonging the pregnancy outweighs the risk of stillbirth. Perinatal mortality of singletons is increased significantly after 42 weeks, whereas perinatal mortality in twins starts to increase significantly after 37 weeks. Recent, large cohort studies have showed significantly higher ...
Shek Noel Wan Man NW Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong Special Administrative Region; Fetal Medicine Centre, Birmingham Women's Foundation NHS Trust, Edgbaston, Birmingham, UK. Electronic address: - - 2013
Single-twin demise can pose substantial risks for the surviving co-twin, including increased risk of fetal loss, preterm delivery, neurovascular injury, and end-organ damage. In this chapter, we summarise recently published research on the causes of single twin demise, the pathophysiology of injury to the surviving co-twin, and the evidence for ...
Oliver Edward R - - 2013
Objectives- The purpose of this study was to test the hypothesis that using the formula of a prolate ellipsoid to estimate parabiotic twin mass correlates better with findings of pump twin compromise than using the sonographic method of Moore et al (Am J Obstet Gynecol 1990; 163:907-912). Methods- A 10-year ...
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